CN105535094A - Traditional Chinese medicine composition for facilitating beast, bird and fish production performance - Google Patents
Traditional Chinese medicine composition for facilitating beast, bird and fish production performance Download PDFInfo
- Publication number
- CN105535094A CN105535094A CN201610016270.0A CN201610016270A CN105535094A CN 105535094 A CN105535094 A CN 105535094A CN 201610016270 A CN201610016270 A CN 201610016270A CN 105535094 A CN105535094 A CN 105535094A
- Authority
- CN
- China
- Prior art keywords
- extract
- chinese medicine
- angelicae sinensis
- flos lonicerae
- radix astragali
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 42
- 239000000203 mixture Substances 0.000 title claims abstract description 24
- 241000251468 Actinopterygii Species 0.000 title abstract description 5
- 238000004519 manufacturing process Methods 0.000 title abstract description 5
- 239000000284 extract Substances 0.000 claims abstract description 64
- 239000009636 Huang Qi Substances 0.000 claims description 31
- 241000628997 Flos Species 0.000 claims description 29
- 239000009188 angelicae sinensis extract Substances 0.000 claims description 26
- 238000002360 preparation method Methods 0.000 claims description 22
- 238000010438 heat treatment Methods 0.000 claims description 10
- 230000035558 fertility Effects 0.000 claims description 9
- 238000002844 melting Methods 0.000 claims description 9
- 230000008018 melting Effects 0.000 claims description 9
- 239000002552 dosage form Substances 0.000 claims description 8
- 229940079593 drug Drugs 0.000 claims description 8
- 239000008187 granular material Substances 0.000 claims description 8
- 244000144977 poultry Species 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 7
- 239000002775 capsule Substances 0.000 claims description 6
- -1 sublimed preparation Substances 0.000 claims description 6
- 239000003826 tablet Substances 0.000 claims description 6
- 239000002674 ointment Substances 0.000 claims description 3
- 239000006187 pill Substances 0.000 claims description 3
- 239000006196 drop Substances 0.000 claims description 2
- 239000007924 injection Substances 0.000 claims description 2
- 238000002347 injection Methods 0.000 claims description 2
- 239000000243 solution Substances 0.000 claims description 2
- 239000007921 spray Substances 0.000 claims description 2
- 239000000829 suppository Substances 0.000 claims description 2
- 235000006533 astragalus Nutrition 0.000 abstract description 4
- 241001061264 Astragalus Species 0.000 abstract description 2
- 210000004233 talus Anatomy 0.000 abstract description 2
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 235000011203 Origanum Nutrition 0.000 abstract 1
- 241001529744 Origanum Species 0.000 abstract 1
- 239000003921 oil Substances 0.000 description 24
- 210000004369 blood Anatomy 0.000 description 15
- 239000008280 blood Substances 0.000 description 15
- 239000012467 final product Substances 0.000 description 8
- 229920001353 Dextrin Polymers 0.000 description 7
- 239000004375 Dextrin Substances 0.000 description 7
- 235000019425 dextrin Nutrition 0.000 description 7
- 239000000047 product Substances 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 206010012735 Diarrhoea Diseases 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 210000000952 spleen Anatomy 0.000 description 6
- 241000252230 Ctenopharyngodon idella Species 0.000 description 5
- 239000000654 additive Substances 0.000 description 5
- 230000000996 additive effect Effects 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- 230000001737 promoting effect Effects 0.000 description 5
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 description 4
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 4
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 description 4
- 229940074393 chlorogenic acid Drugs 0.000 description 4
- 235000001368 chlorogenic acid Nutrition 0.000 description 4
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 4
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 description 4
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 description 4
- 201000006549 dyspepsia Diseases 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 210000004185 liver Anatomy 0.000 description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 3
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 229930195725 Mannitol Natural products 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- 229930006000 Sucrose Natural products 0.000 description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 3
- 241000282887 Suidae Species 0.000 description 3
- 229940024606 amino acid Drugs 0.000 description 3
- 235000001014 amino acid Nutrition 0.000 description 3
- 150000001413 amino acids Chemical class 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000029087 digestion Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- LRDGATPGVJTWLJ-UHFFFAOYSA-N luteolin Natural products OC1=CC(O)=CC(C=2OC3=CC(O)=CC(O)=C3C(=O)C=2)=C1 LRDGATPGVJTWLJ-UHFFFAOYSA-N 0.000 description 3
- 235000009498 luteolin Nutrition 0.000 description 3
- 239000000594 mannitol Substances 0.000 description 3
- 235000010355 mannitol Nutrition 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 235000019698 starch Nutrition 0.000 description 3
- 229940032147 starch Drugs 0.000 description 3
- 239000005720 sucrose Substances 0.000 description 3
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 241000045403 Astragalus propinquus Species 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 239000003390 Chinese drug Substances 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- 206010057190 Respiratory tract infections Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 239000005844 Thymol Substances 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- RECUKUPTGUEGMW-UHFFFAOYSA-N carvacrol Chemical compound CC(C)C1=CC=C(C)C(O)=C1 RECUKUPTGUEGMW-UHFFFAOYSA-N 0.000 description 2
- HHTWOMMSBMNRKP-UHFFFAOYSA-N carvacrol Natural products CC(=C)C1=CC=C(C)C(O)=C1 HHTWOMMSBMNRKP-UHFFFAOYSA-N 0.000 description 2
- 235000007746 carvacrol Nutrition 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 230000036737 immune function Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- WYXXLXHHWYNKJF-UHFFFAOYSA-N isocarvacrol Natural products CC(C)C1=CC=C(O)C(C)=C1 WYXXLXHHWYNKJF-UHFFFAOYSA-N 0.000 description 2
- 239000008101 lactose Substances 0.000 description 2
- 239000000314 lubricant Substances 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- IQPNAANSBPBGFQ-UHFFFAOYSA-N luteolin Chemical compound C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(O)C(O)=C1 IQPNAANSBPBGFQ-UHFFFAOYSA-N 0.000 description 2
- 210000002540 macrophage Anatomy 0.000 description 2
- 235000019359 magnesium stearate Nutrition 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- 230000035755 proliferation Effects 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 230000035882 stress Effects 0.000 description 2
- 229960000790 thymol Drugs 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- QIJRTFXNRTXDIP-UHFFFAOYSA-N (1-carboxy-2-sulfanylethyl)azanium;chloride;hydrate Chemical compound O.Cl.SCC(N)C(O)=O QIJRTFXNRTXDIP-UHFFFAOYSA-N 0.000 description 1
- KSEBMYQBYZTDHS-HWKANZROSA-M (E)-Ferulic acid Natural products COC1=CC(\C=C\C([O-])=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-M 0.000 description 1
- WMBOCUXXNSOQHM-FLIBITNWSA-N (Z)-3-butylidenephthalide Chemical compound C1=CC=C2C(=C/CCC)/OC(=O)C2=C1 WMBOCUXXNSOQHM-FLIBITNWSA-N 0.000 description 1
- IQVQXVFMNOFTMU-FLIBITNWSA-N (Z)-ligustilide Chemical compound C1CC=CC2=C1C(=C/CCC)/OC2=O IQVQXVFMNOFTMU-FLIBITNWSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 1
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 241000208173 Apiaceae Species 0.000 description 1
- SMDOOINVMJSDPS-UHFFFAOYSA-N Astragaloside Natural products C1=C(O)C(OC)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)OC2C(C(OC3C(C(O)C(O)C(CO)O3)O)C(O)C(CO)O2)O)=C1 SMDOOINVMJSDPS-UHFFFAOYSA-N 0.000 description 1
- 208000004429 Bacillary Dysentery Diseases 0.000 description 1
- 244000001582 Canarium odontophyllum Species 0.000 description 1
- 235000016299 Canarium odontophyllum Nutrition 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 229920000858 Cyclodextrin Polymers 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 241000316770 Deschampsia cespitosa var. alpina Species 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 208000015220 Febrile disease Diseases 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 241000222336 Ganoderma Species 0.000 description 1
- 206010017915 Gastroenteritis shigella Diseases 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 244000303199 Lamium album Species 0.000 description 1
- 235000009199 Lamium album Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 229920000881 Modified starch Polymers 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 241000238370 Sepia Species 0.000 description 1
- 241000607762 Shigella flexneri Species 0.000 description 1
- 206010041925 Staphylococcal infections Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
- IQVQXVFMNOFTMU-DHZHZOJOSA-N Z-ligustilide Natural products C1CC=CC2=C1C(=C/CCC)\OC2=O IQVQXVFMNOFTMU-DHZHZOJOSA-N 0.000 description 1
- 235000011054 acetic acid Nutrition 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 235000010419 agar Nutrition 0.000 description 1
- 229940072056 alginate Drugs 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 229910000288 alkali metal carbonate Inorganic materials 0.000 description 1
- 150000008041 alkali metal carbonates Chemical class 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 239000003674 animal food additive Substances 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000000146 antalgic effect Effects 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 230000002180 anti-stress Effects 0.000 description 1
- 230000002785 anti-thrombosis Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 238000009360 aquaculture Methods 0.000 description 1
- 244000144974 aquaculture Species 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- QMNWISYXSJWHRY-XWJCTJPOSA-N astragaloside Chemical compound O1[C@H](C(C)(O)C)CC[C@]1(C)[C@@H]1[C@@]2(C)CC[C@]34C[C@]4(CC[C@H](O[C@H]4[C@@H]([C@@H](O)[C@H](O)CO4)O)C4(C)C)C4[C@@H](O[C@H]4[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O4)O)CC3[C@]2(C)C[C@@H]1O QMNWISYXSJWHRY-XWJCTJPOSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- NKWPZUCBCARRDP-UHFFFAOYSA-L calcium bicarbonate Chemical compound [Ca+2].OC([O-])=O.OC([O-])=O NKWPZUCBCARRDP-UHFFFAOYSA-L 0.000 description 1
- 229910000020 calcium bicarbonate Inorganic materials 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 235000010216 calcium carbonate Nutrition 0.000 description 1
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical compound [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 description 1
- 239000008116 calcium stearate Substances 0.000 description 1
- 235000013539 calcium stearate Nutrition 0.000 description 1
- 230000006652 catabolic pathway Effects 0.000 description 1
- 230000032677 cell aging Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 208000035850 clinical syndrome Diseases 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000002508 compound effect Effects 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 210000004351 coronary vessel Anatomy 0.000 description 1
- 229960001305 cysteine hydrochloride Drugs 0.000 description 1
- ACYGYJFTZSAZKR-UHFFFAOYSA-J dicalcium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Ca+2].[Ca+2].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O ACYGYJFTZSAZKR-UHFFFAOYSA-J 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- KSEBMYQBYZTDHS-HWKANZROSA-N ferulic acid Chemical compound COC1=CC(\C=C\C(O)=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-N 0.000 description 1
- 235000001785 ferulic acid Nutrition 0.000 description 1
- 229940114124 ferulic acid Drugs 0.000 description 1
- KSEBMYQBYZTDHS-UHFFFAOYSA-N ferulic acid Natural products COC1=CC(C=CC(O)=O)=CC=C1O KSEBMYQBYZTDHS-UHFFFAOYSA-N 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 208000003512 furunculosis Diseases 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 210000000224 granular leucocyte Anatomy 0.000 description 1
- 239000007952 growth promoter Substances 0.000 description 1
- 230000003394 haemopoietic effect Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000008821 health effect Effects 0.000 description 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 230000002607 hemopoietic effect Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 230000002443 hepatoprotective effect Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
- 235000011167 hydrochloric acid Nutrition 0.000 description 1
- 230000031891 intestinal absorption Effects 0.000 description 1
- FZWBNHMXJMCXLU-BLAUPYHCSA-N isomaltotriose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)O1 FZWBNHMXJMCXLU-BLAUPYHCSA-N 0.000 description 1
- 239000010977 jade Substances 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 150000002596 lactones Chemical class 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- WMBOCUXXNSOQHM-UHFFFAOYSA-N n-butylidenephthalide Natural products C1=CC=C2C(=CCCC)OC(=O)C2=C1 WMBOCUXXNSOQHM-UHFFFAOYSA-N 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229940068968 polysorbate 80 Drugs 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000000384 rearing effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 201000005113 shigellosis Diseases 0.000 description 1
- 150000003376 silicon Chemical class 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000002639 sodium chloride Nutrition 0.000 description 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
- 239000001540 sodium lactate Substances 0.000 description 1
- 229940005581 sodium lactate Drugs 0.000 description 1
- 235000011088 sodium lactate Nutrition 0.000 description 1
- 235000010262 sodium metabisulphite Nutrition 0.000 description 1
- 229940080313 sodium starch Drugs 0.000 description 1
- 235000010265 sodium sulphite Nutrition 0.000 description 1
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
- 235000019345 sodium thiosulphate Nutrition 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 235000010356 sorbitol Nutrition 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 208000015339 staphylococcus aureus infection Diseases 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229960004793 sucrose Drugs 0.000 description 1
- 239000001117 sulphuric acid Substances 0.000 description 1
- 235000011149 sulphuric acid Nutrition 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine composition for facilitating the beast, bird and fish production performance. The traditional Chinese medicine composition is prepared from, by weight, 50-200 g of an extract from angelica sinensis, 50-200 g of an extract from astragalus, 50-200 g of an extract from honeysuckle and 30-200 g of origanum oil.
Description
Technical field:
The present invention relates to a kind of Chinese medicine compound pharmaceutical composition, particularly a kind of Chinese medicine compound pharmaceutical composition promoting poultry and Fish fertility performance.
Background technology:
In intensive culture, poultry because of farrowing, wean etc. stress, produce irritability syndrome.Stress in poultry be in sub-health state, insufficiency of vital energy and blood, produce dyspepsia, diarrhoea, cause fertility performance, immune function is low, has a strong impact on growth promoter.The traditional Chinese medical science is said, should to regulate QI and blood, QI invigorating strengthening the spleen, to improve poultry own bodies state.
The traditional Chinese medical science, Chinese medicine are good at conditioning the most.Under the theory of " healthy aquaculture ", an organism, in optimum health state, could effectively play best fertility performance, produce top quality livestock products.Due to Chinese medicine and preparation rich in proteins, aminoacid, vitamin and trace element, so have nutrition and medicinal two attribute concurrently.Can growth of animal be promoted as feed additive, improve fertility performance.Meanwhile, improve the fertility performance of animal as coordination body physiological function with Chinese medicine additive, toxic and side effects is little, does not produce drug resistance, noresidue, has incomparable advantage and deep theoretical basis.Therefore, exploitation Chinese medicine additive substitutes the feedstuff additive products such as existing chemicals, feeding antibiotic, has broad application prospects in breeding production.
Chinese medicine thinks that the basic of gas is united at kidney in lung spleen.Blood follows in row body, the nutrition whole body.Disease is if any short, sluggish, the absurd row of QI and blood.The cause of disease or by caloric stimulation, or prolonged illness consume, or because of farrowing, wound, bleed too much.For asthenia of qi and blood, animals with spleen deficiency exploitation Chinese medicine compound according to instruction of Chinese Medicine theory for clinical syndromes such as insufficiency of vital energy and blood, dyspepsia, diarrhoea, from " vigorate qi and replenish the blood, detoxicating, killing bacteria.Facilitating digestion absorb, improve the price of deed " etc. aspect start with, with Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract, Herba Origani oil composition disease-resistant growth-promoting Chinese medicine compound, develop the herbal medicine additive for promoting poultry and Fish fertility performance.
Summary of the invention:
The present invention prepares a kind of Chinese medicine composition, described Chinese medicine composition with Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract, Herba Origani oil for raw material, is prepared from by the crude drug of following weight proportion:
Radix Angelicae Sinensis extract 50-250g Radix Astragali extract 50-250g Flos Lonicerae extract 50-200g Herba Origani oil 30-200g
Preferably, Chinese medicine composition of the present invention, is prepared from by the crude drug of following weight proportion:
Radix Angelicae Sinensis extract 150-250g Radix Astragali extract 150-250g Flos Lonicerae extract 150-200g Herba Origani oil 50-150g
It is most preferred,
Radix Angelicae Sinensis extract 200g, Radix Astragali extract 200g, Flos Lonicerae extract 150g, Herba Origani oil 100g
Chinese medicine composition of the present invention, wherein said:
The present invention treats with Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract, Herba Origani oil or alleviates insufficiency of vital energy and blood, dyspepsia, diarrhoea for herbal medicine patent medicine prepared by raw material.For promoting poultry, fish growth; Improve product quality.There is vigorate qi and replenish the blood, detoxicating, killing bacteria, invigorating the spleen to arrest diarrhea.Facilitating digestion absorbs, improve the functions such as the price of deed.
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature.Return liver, the heart, spleen channel.Can enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation, be applicable to heart-liver blood deficiency card.Radix Angelicae Sinensis polysaccharide activates macrophage, lymphocyte etc. in hematopoieticmicroenviron-ment by direct and (or) degradation pathways, also muscular tissue can be stimulated, promote that it produces the hematopoietic regulation factor, and then promotion functions hematopoietic stem cell granular leukocyte macrophage colony becomes the proliferation and differentiation of unit (CFU-GM), stimulate proliferation of Bone Marrow CFU-GM hemopoietic.In addition, when giving back, there is antithrombotic, anti-inflammatory and antalgic, blood sugar lowering, protecting the liver the effects such as sharp liver.Radix Angelicae Sinensis extract is the root of Umbelliferae archangel Radix Angelicae Sinensis.Constituent: containing ligustilide (ligusiilide), n-butene acyl lactone (n-butylidenephthalide), ferulic acid, nicotinic acid, sucrose and several amino acids, and the composition such as sesquiterpenoids, product specification: Rhizoma Ligustici lactone content 1%.
The Radix Astragali: the sweet temperature of property, returns lung meridian, has tonifying Qi and lifting yang, function that benefit defends consolidating superficial resistance.Through the precious Ganoderma of conventional Radix Astragali compatibility fine jade decoct soup or soaked generation tea-drinking, there is good disease-prevention health effect.Modern medicine study shows, the Radix Astragali have enhancing human body immunity function,
protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.The Radix Astragali can not only coronary artery dilator, improves blood supply of cardiac muscle, improves immunologic function, and can the process of delaying cell aging.Radix Astragali extract: the dry root of leguminous plant Radix Astagali Astragalusmembranaceus (Fisch.) Bge.Var.mongholicus (Bge) Hsiao or pod membrane Radix Astragali Astragalusmembranaceus (Fisch.) Bge..Product characteristics: brown color fine powder.Product specification: astragalus polysaccharides Polysacchrides50%; Astragaloside 0.2%.
Flos Lonicerae: Flos Lonicerae effect mainly heat-clearing and toxic substances removing, cures mainly epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furunculosis etc.Modern study proves, Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, stronger restraint is had to the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc., in addition also can enhancing immunity, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, can be used for the treatment of respiratory tract infection, bacillary dysentery, acute urinary, hypertension etc. with other medicines compatibility.Flos Lonicerae extract: effective ingredient is chlorogenic acid (chlorogenicacid) and Luteolin (Luteolin) sepia or yellow-brown solid powder, bitter in the mouth; HPLC detects containing chlorogenic acid 5%
Herba Origani oil: Herba Origani oil is the volatile oil extracted from plant ' Adeps Bovis seu Bubali ', is pale yellow oily liquid body, is mainly made up of carvacrol, thymol.Wherein carvacrol >=88% and thymol >=2%, there is heat clearing away, removing dampness, drive away summer heat, induce sweat, regulate the flow of vital energy extremely strong sterilization, bacteriostasis, the volatile oil extracted from Adeps Bovis seu Bubali, commonly causing enteritis antibacterial and shigella flexneri to 31 kinds, is the pure Chinese medicine additive most with broad-spectrum antiseptic.
Above composition of the present invention is by weight as proportioning, can increase according to corresponding proportion when producing or reduce, as large-scale production can by kilogram in units of, or in units of ton, small-scale production also can in units of milligram, weight can increase or reduce, but the constant rate of raw medicinal herbs weight proportion between each composition.
The ratio of above weight proportion is through that science screening obtains, for special circumstances, as serious symptom or mild, fat or modest, can the proportioning of amount of corresponding adjustment composition, and increase or reduce being no more than 100%, drug effect is constant.
Single medicinal material more than in composition, especially ministerial drug and adjuvant drug, also can be replaced by the suitable Chinese medicine with the identical property of medicine, its drug effect of the Chinese medicine preparation after replacement is constant.
Chinese medicine composition of the present invention is by the pharmaceutically active substance of above-mentioned formula is prepared into pharmaceutical dosage forms according to galenic pharmacy routine techniques.
When being prepared into pharmaceutical preparation, medicine acceptable carrier can be added if desired, preparing according to the routine techniques of galenic pharmacy.Pharmaceutical dosage forms of the present invention, exists in a unit, and described unit dosage form refers to the unit of preparation, as every sheet of tablet, and every capsules of capsule, granule every bag etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, capsule, granule, pill, powder, unguentum, sublimed preparation, powder, solution, injection, suppository, spray, drop, patch.Preparation of the present invention, preferably peroral dosage form, as: capsule, tablet, oral liquid, granule, pill, powder, sublimed preparation, unguentum etc.
Chinese medicine preparation of the present invention, the preparation of its oral administration can containing conventional excipient, such as binding agent, filler, diluent, tablet agent, lubricant, disintegrating agent, coloring agent, flavoring agent and wetting agent.The filler be suitable for comprises starch, sucrose, cellulose, mannitol, lactose and other similar filler.Suitable disintegrating agent comprises starch, polyvinylpyrrolidone and starch derivatives, such as sodium starch glycollate.Suitable lubricant comprises, such as magnesium stearate.By mixing, fill, the method that tabletting etc. are conventional prepares solid oral composition.Repeatedly mix and active substance can be made to be distributed in those compositionss of a large amount of filler of whole use, conventional adjunct ingredient comprises: mannitol, sorbitol, sodium pyrosulfite, sodium sulfite, sodium thiosulfate, cysteine hydrochloride, TGA, methionine, vitamin C, EDETATE SODIUM, Ethylenediaminetetraacetic Acid Calcium Salt, the alkali-metal carbonate of monovalence, acetate, phosphate or its aqueous solution, hydrochloric acid, acetic acid, sulphuric acid, phosphoric acid, aminoacid, sodium chloride, potassium chloride, sodium lactate, xylitol, maltose, glucose, fructose, dextran, glycine, starch, sucrose, lactose, mannitol, silicon derivative, cellulose and its derivates, alginate, gelatin, polyvinylpyrrolidone, glycerol, POLYSORBATE 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Preparation of the present invention according to condition determination usage and dosage, can take 1-2 time in use every day, each by per kilogram of body weight 0.5-5g dosage.
The present invention further provides the preparation method of Chinese medicine composition of the present invention, described preparation method, step is as follows:
Get Herba Origani oil heating and melting, add the 3 taste extracts such as Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract, be uniformly mixed, dry, pulverized 100 mesh sieves, and added appropriate dextrin, mixing, makes 1000g, subpackage and get final product.
Wherein said Herba Origani oil, Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract are purchase on market and obtain, and meet the product of pharmaceutical standards.
Confirm through study of pharmacy, this preparation process is stablized, and is applicable to large production.
The present invention finds unexpectedly, and the collocation of each component of the present invention has synergistic function, has treatment or alleviates insufficiency of vital energy and blood, dyspepsia, diarrhoea.For promoting that suckling piglet grows; Improve fattening pig meat.There is vigorate qi and replenish the blood, detoxicating, killing bacteria, invigorating the spleen to arrest diarrhea.Facilitating digestion absorbs, improve the functions such as the price of deed.
Below by way of experimental data, beneficial effect of the present invention is described:
Pharmacodynamics is tested
1. this Chinese medicine is to the experimental result of Performance of Finishing Pigs:
Laboratory animal: age in days is the DABAI hybridization growing and fattening pigs 80 of 60 days, and be divided into 2 groups, Chinese drug-treated group counterpoise 24.5 ± 0.5kg, matched group 24.7 ± 0.8kg, grouping situation is in table 1.
This Chinese prescription of table 1 is on the impact of Performance of Finishing Pigs
2. this Chinese medicine is to the result of the test of broiler chicken
Pulling out the healthy commodity chickling of beneficial family carries out test in 7 weeks to select 1 age in days to like.Rearing conditions is that hassock material flat supporting in all-in and all-out ground is given up, and keeps clean, notes ventilating, make a record.Free choice feeding, freely drinks water.
Table 2 Chinese drug-treated group is on the impact of fertility performance
* significant difference P<0.05
On the impact of Ctenopharyngodon idellus
Get each 40 tails of the normal Ctenopharyngodon idellus of body constitution at random, average weight (115.24 ± 2.05) g.Be divided into two groups at random to support in laboratory water tank.Duration of test water temperature is 22-24 DEG C.Matched group Ctenopharyngodon idellus is thrown something and fed foundation bait, and experimental group Ctenopharyngodon idellus is thrown something and fed and be with the addition of the bait of 0.2% Chinese medicine compound.Feedstuff is thrown something and fed 2 times every day.Feeding volume rests in can to ingest 24h and showing a small surplus for fish.Cleaning fish box every 1d and change water, quantity of exchanged water is that the 1/2-2/3 of whole water volume raises 20d.
Table 3 is each group Growth of Grass Carps Ctenopharyngodon Idellus result after raising 20d
As can be seen from Table 3, Chinese medicine compound effect is better than matched group
Detailed description of the invention:
Further illustrate the present invention by the following examples, but not as limitation of the present invention.
Embodiment 1
Radix Angelicae Sinensis extract 200g, Radix Astragali extract 200g, Flos Lonicerae extract 150g, Herba Origani oil 100g
The preparation method of granule is as follows:
Get Herba Origani oil heating and melting, add the 3 taste extracts such as Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract, be uniformly mixed, dry, pulverized 100 mesh sieves, and added appropriate dextrin, mixing, makes 1000g, subpackage and get final product.
Embodiment 2
Radix Angelicae Sinensis extract 200g, Radix Astragali extract 200g, Flos Lonicerae extract 150g, Herba Origani oil 100g
The preparation method of tablet is as follows:
Get Herba Origani oil heating and melting, add the 3 taste extracts such as Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract, be uniformly mixed, dry, pulverized 100 mesh sieves, and added appropriate dextrin, tabletting subpackage and get final product.
Embodiment 3
Radix Angelicae Sinensis extract 200g, Radix Astragali extract 200g, Flos Lonicerae extract 150g, Herba Origani oil 100g
The preparation method of capsule is as follows:
Get Herba Origani oil heating and melting, add the 3 taste extracts such as Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract, be uniformly mixed, dry, pulverized 100 mesh sieves, and added appropriate dextrin, mixing, encapsulated and get final product.
Embodiment 4
Radix Angelicae Sinensis extract 200g, Radix Astragali extract 200g, Flos Lonicerae extract 150g, Herba Origani oil 100g
The preparation method of oral liquid is as follows:
Get Herba Origani oil heating and melting, add the 3 taste extracts such as Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract, be uniformly mixed, dry, pulverized 100 mesh sieves, add water subpackage and get final product.
Embodiment 5
Radix Angelicae Sinensis extract 200g, Radix Astragali extract 200g, Flos Lonicerae extract 150g, Herba Origani oil 100g
The preparation method of granule is as follows:
Get Herba Origani oil heating and melting, add the 3 taste extracts such as Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract, be uniformly mixed, dry, pulverized 100 mesh sieves, and added appropriate dextrin, mixing, makes 1000g, subpackage and get final product.
Embodiment 6
Radix Angelicae Sinensis extract 200g, Radix Astragali extract 200g, Flos Lonicerae extract 150g, Herba Origani oil 100g
The preparation method of granule is as follows:
Get Herba Origani oil heating and melting, add the 3 taste extracts such as Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract, be uniformly mixed, dry, pulverized 100 mesh sieves, and added appropriate dextrin, mixing, makes 1000g, subpackage and get final product.
Embodiment 7
Radix Angelicae Sinensis extract 200g, Radix Astragali extract 200g, Flos Lonicerae extract 150g, Herba Origani oil 100g
The preparation method of granule is as follows:
Get Herba Origani oil heating and melting, add the 3 taste extracts such as Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract, be uniformly mixed, dry, pulverized 100 mesh sieves, and added appropriate dextrin, mixing, makes 1000g, subpackage and get final product.
Claims (5)
1. promote a Chinese medicine composition for poultry and Fish fertility performance, it is characterized in that, be prepared from by the crude drug of following weight proportion: Radix Angelicae Sinensis extract 50-200g, Radix Astragali extract 50-200g, Flos Lonicerae extract 50-200g, Herba Origani oil 30-200g.
2. Chinese medicine composition according to claim 1, is characterized in that, is prepared from by the crude drug of following weight proportion:
Radix Angelicae Sinensis extract 200g, Radix Astragali extract 200g, Flos Lonicerae extract 150g, Herba Origani oil 100g.
3. compositions according to claim 1 is any pharmaceutically useful dosage form.
4. compositions according to claim 3, described dosage form is selected from: tablet, capsule, granule, pill, powder, unguentum, sublimed preparation, powder, solution, injection, suppository, spray, drop, patch.
5. the preparation method of compositions according to claim 1, step is as follows: get the Rhizoma Anemarrhenae, Bulbus Fritillariae Uninbracteatae, get Herba Origani oil heating and melting, add the 3 taste extracts such as Radix Angelicae Sinensis extract, Radix Astragali extract, Flos Lonicerae extract, be uniformly mixed, dry, pulverized 100 mesh sieves, and made compositions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610016270.0A CN105535094A (en) | 2016-01-11 | 2016-01-11 | Traditional Chinese medicine composition for facilitating beast, bird and fish production performance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610016270.0A CN105535094A (en) | 2016-01-11 | 2016-01-11 | Traditional Chinese medicine composition for facilitating beast, bird and fish production performance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105535094A true CN105535094A (en) | 2016-05-04 |
Family
ID=55815019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610016270.0A Pending CN105535094A (en) | 2016-01-11 | 2016-01-11 | Traditional Chinese medicine composition for facilitating beast, bird and fish production performance |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105535094A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106334003A (en) * | 2016-10-20 | 2017-01-18 | 中悦民安（北京）科技发展有限公司 | Chinese herbal compound for livestock labor induction and preparation method thereof and application |
| CN106421114A (en) * | 2016-10-09 | 2017-02-22 | 北京农学院 | Traditional Chinese medicine composition for promoting livestock delivery |
| CN109007455A (en) * | 2018-10-11 | 2018-12-18 | 内江师范学院 | A kind of fish meal and preparation method thereof containing angelica extract |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102379931A (en) * | 2011-11-17 | 2012-03-21 | 刘清泉 | Novel application of Chinese medicinal composition |
| CN102552379A (en) * | 2012-01-06 | 2012-07-11 | 韩健宝 | Veterinary drug composition capable of enhancing immunity and preparation method of veterinary drug composition |
-
2016
- 2016-01-11 CN CN201610016270.0A patent/CN105535094A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102379931A (en) * | 2011-11-17 | 2012-03-21 | 刘清泉 | Novel application of Chinese medicinal composition |
| CN102552379A (en) * | 2012-01-06 | 2012-07-11 | 韩健宝 | Veterinary drug composition capable of enhancing immunity and preparation method of veterinary drug composition |
Non-Patent Citations (2)
| Title |
|---|
| 李春红等: "当归补血散对高龄蛋鸡生产性能及蛋品质的影响", 《中国饲料》 * |
| 李益和等: "中草药添加剂在家禽生产中的应用", 《养禽与禽病防治》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106421114A (en) * | 2016-10-09 | 2017-02-22 | 北京农学院 | Traditional Chinese medicine composition for promoting livestock delivery |
| CN106334003A (en) * | 2016-10-20 | 2017-01-18 | 中悦民安（北京）科技发展有限公司 | Chinese herbal compound for livestock labor induction and preparation method thereof and application |
| CN109007455A (en) * | 2018-10-11 | 2018-12-18 | 内江师范学院 | A kind of fish meal and preparation method thereof containing angelica extract |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102940155B (en) | Duckling feed for cherry valley duck and preparation method thereof | |
| CN103749982B (en) | Feed for improving egg yield, traditional Chinese medicine additive and preparation method thereof | |
| CN103238756A (en) | Compound feed for finishing pigs and preparation method thereof | |
| CN103039745A (en) | Daily ration concentrated feed of egg-laying sheldrake and preparation method thereof | |
| CN105497879A (en) | Anti-stress traditional Chinese medicine compound capable of improving product flavor | |
| CN104491204A (en) | Traditional Chinese medicine composition for preventing and treating bacterial and virus infection of livestock and poultry and preparation method of traditional Chinese medicine composition | |
| CN104206786A (en) | Traditional Chinese medicine microecological preparation for meat chicken, preparation method and applications thereof | |
| CN105166544A (en) | Pig mixed feed and preparation method thereof | |
| CN105535163A (en) | Traditional Chinese medicine composition for improving flavor quality of livestock and poultry and aquatic products | |
| CN105535094A (en) | Traditional Chinese medicine composition for facilitating beast, bird and fish production performance | |
| CN104543576B (en) | Prevent and treat composite vegetables extractive feed addictive and its preparation method application of grice diarrhoea | |
| CN101601756A (en) | Chinese medicine composition of treatment chicken colibacillosis and preparation method thereof | |
| CN105010891A (en) | Chicken feed containing Chinese herbal medicine additive | |
| CN108853343A (en) | It is a kind of to prevent and treat the Chinese materia medica preparation of chicken mycotoxicosis, preparation method and application | |
| CN103609893A (en) | Cattle feed for promoting digestion | |
| CN104970220A (en) | Compound feed for sows in suckling period and preparation method thereof | |
| CN104547770A (en) | Fermented traditional Chinese medicament for promoting growth of livestock and poultry and preparation method for fermented traditional Chinese medicament | |
| CN103960542A (en) | Feed and traditional Chinese medicine composition for preventing and treating swine eperythrozoonosis | |
| CN106213029A (en) | Broiler fodder | |
| CN107019774B (en) | Traditional Chinese medicine composition for treating intestinal diseases of livestock and poultry and application thereof | |
| CN106135667A (en) | The poultry of a kind of alternative antibiotic local flavor zacate additive and preparation method thereof | |
| CN105166484A (en) | Chicken feed containing Chinese herbal medicine additives | |
| CN110812389A (en) | Soluble granule for improving pig immunity and preparation method thereof | |
| CN103610975A (en) | Preparation method of cattle medicine for promoting digestion | |
| CN110179009A (en) | A kind of natural plant feed raw material compound and preparation method thereof for improving laying hen premunition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information |
Inventor after: Yin Peng Inventor after: Zhao Tianjun Inventor after: Yu Xiaohong Inventor after: Liang Bing Inventor before: Yin Peng Inventor before: Shi Yaran Inventor before: Yu Xiaohong Inventor before: Liang Bing |
|
| COR | Change of bibliographic data | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160504 |
|
| RJ01 | Rejection of invention patent application after publication |