CN105534372B - It is a kind of with antibacterial, disinfection towel and preparation method thereof of going to the lavatory - Google Patents
It is a kind of with antibacterial, disinfection towel and preparation method thereof of going to the lavatory Download PDFInfo
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- CN105534372B CN105534372B CN201610081915.9A CN201610081915A CN105534372B CN 105534372 B CN105534372 B CN 105534372B CN 201610081915 A CN201610081915 A CN 201610081915A CN 105534372 B CN105534372 B CN 105534372B
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- towel
- lavatory
- going
- extract
- parts
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- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 54
- 238000004659 sterilization and disinfection Methods 0.000 title claims abstract description 47
- 238000002360 preparation method Methods 0.000 title claims description 23
- 239000000284 extract Substances 0.000 claims abstract description 126
- 239000012530 fluid Substances 0.000 claims abstract description 67
- 239000004744 fabric Substances 0.000 claims abstract description 39
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- 239000000470 constituent Substances 0.000 claims abstract description 17
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 65
- 238000000034 method Methods 0.000 claims description 36
- 239000000047 product Substances 0.000 claims description 29
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- 235000019441 ethanol Nutrition 0.000 claims description 23
- 239000007788 liquid Substances 0.000 claims description 22
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 18
- 235000013599 spices Nutrition 0.000 claims description 15
- 239000000654 additive Substances 0.000 claims description 13
- 230000000996 additive effect Effects 0.000 claims description 13
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 12
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- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 5
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims description 5
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- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims description 5
- 229940116229 borneol Drugs 0.000 claims description 5
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims description 5
- 235000013399 edible fruits Nutrition 0.000 claims description 5
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 claims description 4
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 claims description 3
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- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 3
- 240000005250 Chrysanthemum indicum Species 0.000 claims description 2
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- WIONIXOBNMDJFJ-UHFFFAOYSA-N Dictamnine Chemical group C1=CC=C2C(OC)=C(C=CO3)C3=NC2=C1 WIONIXOBNMDJFJ-UHFFFAOYSA-N 0.000 description 4
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- 238000005213 imbibition Methods 0.000 description 4
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- VVOAZFWZEDHOOU-UHFFFAOYSA-N magnolol Chemical group OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 description 4
- 239000000463 material Substances 0.000 description 4
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- 210000004877 mucosa Anatomy 0.000 description 3
- GOHMRMDXUXWCDQ-UHFFFAOYSA-N pseudolaric acid B Natural products CC(=O)OC12CCC(C)=CCC11C(=O)OC(C)(C=CC=C(C)C(O)=O)C2CC1 GOHMRMDXUXWCDQ-UHFFFAOYSA-N 0.000 description 3
- VDGOFNMYZYBUDT-YDRCMHEVSA-N pseudolaric acid b Chemical group C([C@@]12OC(C)=O)CC(C(=O)OC)=CC[C@@]11C(=O)O[C@](C)(\C=C\C=C(/C)C(O)=O)[C@@H]2CC1 VDGOFNMYZYBUDT-YDRCMHEVSA-N 0.000 description 3
- VDGOFNMYZYBUDT-UHFFFAOYSA-N pseudolarix acid B Natural products CC(=O)OC12CCC(C(=O)OC)=CCC11C(=O)OC(C)(C=CC=C(C)C(O)=O)C2CC1 VDGOFNMYZYBUDT-UHFFFAOYSA-N 0.000 description 3
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- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
- HKODIGSRFALUTA-ZJQCNOOHSA-N Integerrimine Natural products CC=C1C[C@H](C)[C@@](C)(O)C(=O)OCC2=CCN3CC[C@@H](OC1=O)[C@H]23 HKODIGSRFALUTA-ZJQCNOOHSA-N 0.000 description 2
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- BTHCJHQOYFUIMG-UHFFFAOYSA-N platyphylline Natural products O1C(=O)C(=CC)CC(C)C(C)(O)C(=O)OCC2CCN3C2C1CC3 BTHCJHQOYFUIMG-UHFFFAOYSA-N 0.000 description 2
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- OZPMZVHQAUHYCP-UHFFFAOYSA-N senecionine Natural products CC=C/1CC(C)C(C)(O)C(=O)OC2=CCN3CCC(OC1=O)C23 OZPMZVHQAUHYCP-UHFFFAOYSA-N 0.000 description 2
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- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
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- 240000000774 Cunila origanoides Species 0.000 description 1
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- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 235000014866 Dictamnus albus Nutrition 0.000 description 1
- 241000131458 Elsholtzia Species 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
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- 244000303040 Glycyrrhiza glabra Species 0.000 description 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
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- 244000246386 Mentha pulegium Species 0.000 description 1
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- 229960003872 benzethonium Drugs 0.000 description 1
- UREZNYTWGJKWBI-UHFFFAOYSA-M benzethonium chloride Chemical compound [Cl-].C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 UREZNYTWGJKWBI-UHFFFAOYSA-M 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47K—SANITARY EQUIPMENT NOT OTHERWISE PROVIDED FOR; TOILET ACCESSORIES
- A47K10/00—Body-drying implements; Toilet paper; Holders therefor
- A47K10/16—Paper towels; Toilet paper; Holders therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention relates to a kind of with antibacterial, disinfection towel of going to the lavatory, and the towel of going to the lavatory is formed by the base fabric for having adsorbed antibacterial disinfection medical fluid;The medical fluid includes the active constituent of following parts by weight:8-12 parts of Cortex Dictamni extract, 12-18 parts of Cortex Pseudolaricis extract, 10-15 parts of Herba Senecionis Scandentis extract, 6-10 parts of Magnolia cortex P.E.The towel of going to the lavatory has the effect of the remaining urine of the absorption small private parts after an action of the bowels of women, to keep pudendum cleaning dry and comfortable;Meanwhile the medical fluid of absorption has antibacterial, sterilization and antiinflammation, provides good articles for the small cleaning after an action of the bowels of women, has broad application prospects.
Description
Technical field
The present invention relates to a kind of with antibacterial, disinfection towel of going to the lavatory, while being related to the preparation of above-mentioned towel of going to the lavatory.
Background technique
As attention degree of the masses for personal hygiene aggravates, with antibacterial, disinfection hygienic articles at present
As much-sought-after item.Such as:
Chinese patent CN1062467C discloses a kind of clean-preserving agent, borneol, the original pharmaceutical content for being 1-3 ‰ by weight ratio
For every milliliter 0.3-0.5 grams, the alcohol composition that remaining is 10-15% concentration, crude drug in whole includes climbing groundsel, cortex dictamni, radix saposhnikoviae, Chinese mugwort
Leaf, frutus cnidii, Chinese gall, borneol, which is added, when preparation, after primary medicinal alcohol is soaked, leaked can be prepared by.Keep a public place clean above-mentioned
First woven fabric is penetrated into agent can be made into moist-retaining tissues, can be used in preventing and treating skin disease and gynaecological disease.
Although above-mentioned clean-preserving agent has preferable antibacterial, disinfection and antiinflammation, found in practical application, exist with
Lower Railway Project:
1) women is small after an action of the bowels, and private parts itself is due to there are urine left, needing to inhale using the excellent paper handkerchief of the water imbibition of dry state
Urine, clean is received, and the small requirement for absorbing urine cleaning private parts after an action of the bowels is not achieved in wet tissue.
2) borneol has refrigerant experience sense, and human body is also easy to produce dependence, and the reproductive system for being harmful to women is used for a long time
Health.
Chinese patent CN101869537B discloses a kind of wet tissue of clean yin of Ms that can be sterilized, sterilize.The Ms is clean
The solution of dark and damp towel is made of lactic acid, benzethonium chloride, propylene glycol, sorbierite, medicinal menthol, water.When preparation, cut,
The cotton spun laced fabric sterilize, sterilized is immersed in leaching in prepared solution (being equivalent to antibacterial, disinfection medical fluid)
3-5 hour is steeped, sealed, sterile packs to obtain wet tissue.Wet tissue sealed package, is easy to carry about with one made from above-mentioned medical fluid, user
Just.Place need not be avoided, be not necessarily to cleaning ware, only needing wet tissue one to open can reach clean purpose into lavatory wiping.
Although above-mentioned wet tissue has preferable sterilizing cleaning effect, found in practical application, there are wet tissues inherently
It is hygrometric state, the remaining urine of the small private parts after an action of the bowels of women can not be absorbed, be not able to maintain the shortcomings that private parts dry and comfortable effect.
In addition to the above-mentioned known product enumerated, on the market much with wet tissue that is antibacterial, sterilizing, drug ingedient is in addition to containing
There are certain medicinal herb components, while being also added to some chemical drug ingredient such as benzethonium chlorides, long-time service has skin and mucous membrane
Irritation, and the normal pH value of vagina is easily influenced, it is easy to the breeding of germ, mould instead.
Therefore, need to be proposed that one kind is antibacterial, disinfection is significant and urine convenient for female cleans the dry state women paper used
Towel.
Summary of the invention
To overcome the above disadvantages, the present invention provides a kind of with antibacterial, disinfection towel of going to the lavatory, the towel of going to the lavatory
Base fabric by having adsorbed antibacterial disinfection medical fluid is formed;The medical fluid includes the active constituent of following parts by weight:Cortex Dictamni extract
8-12 parts, 12-18 parts of Cortex Pseudolaricis extract, 10-15 parts of Herba Senecionis Scandentis extract, 6-10 parts of Magnolia cortex P.E.
The concrete mode of above-mentioned " absorption " includes infiltration or spraying etc..
Above-mentioned parts by weight are μ g, mg, g, one of kg well known in the art, or are its multiple, such as 1/100,1/10,10
Times, 100 times etc..
Preferably, the medical fluid includes the active constituent of following parts by weight:10 parts of Cortex Dictamni extract, Cortex Pseudolaricis extract
15 parts, 12 parts of Herba Senecionis Scandentis extract, 8 parts of Magnolia cortex P.E.
Medical fluid of the present invention provides active constituent with cortex dictamni, Golden Larch Bark, climbing groundsel, Cortex Magnoliae Officinalis combination, wherein shaggy-fruited dittany
The main component of bark extract is dictamine, and the main component of Cortex Pseudolaricis extract is Pseudo laric acid B, Herba Senecionis Scandentis extract master
Wanting ingredient is senecionine, and the main active of Magnolia cortex P.E is magnolol, above-mentioned active constituent compatible use, it is ensured that
Quality of liquid medicine.
Ordinary commercial products can be used in above-mentioned active constituent, in order to ensure medical fluid/towel of going to the lavatory is antibacterial, the effect of disinfection,
Cortex Dictamni extract of the present invention, Cortex Pseudolaricis extract, Herba Senecionis Scandentis extract, Magnolia cortex P.E preferably pass through as described below
Method is extracted to obtain.
The extracting method of the Cortex Dictamni extract is as follows:By cortex dictamni grinding and sieving (preferably 30 mesh), according to 1:15-
1:20 solid-liquid ratio (g:Ml), 80-90min is extracted with the EtOH Sonicate of volume fraction 85%-95%, concentrated extracting solution is at medicinal extract
(preferably relative density be 1.1-1.3 medicinal extract) to get, wherein the frequency of preferred ultrasonic extraction is 20-60kHz, and power is
400-1200W;
It is preferred that cortex dictamni is smashed it through 30 meshes, according to 1:16-1:19 solid-liquid ratio (g:Ml), volume fraction is used
The EtOH Sonicate of 88%-92% extracts 83-87min, concentrated extracting solution at the medicinal extract of relative density 1.1-1.3 to get, wherein
The frequency of ultrasonic extraction is 40kHz, power 500W.
Using said extracted method, the recovery rate of effective component dictamine can be made to greatly improve, make the suppression in prescription
Bacterium bactericidal effect is also improved simultaneously.
The extracting method of the Cortex Pseudolaricis extract is as follows:By Golden Larch Bark grinding and sieving (preferably 30 mesh), according to 1:10-
1:18 solid-liquid ratio (g:Ml), 15-25min is extracted with the EtOH Sonicate of volume fraction 80%-90%, concentrated extracting solution is at medicinal extract
(preferably relative density be 1.1-1.3 medicinal extract) to get;Wherein, preferably the frequency of ultrasonic extraction is 20-60kHz, and power is
400-1200W;
Using said extracted method, it can be ensured that the recovery rate of Pseudo laric acid B, it is ensured that prescription has good antibacterial kill
Bacterium effect.
It is preferred that Golden Larch Bark is smashed it through 30 meshes, according to 1:12 solid-liquid ratio (g:Ml), with volume fraction 88%-92%
EtOH Sonicate extract 18-22min, concentrated extracting solution at relative density be 1.1-1.3 medicinal extract to get;Wherein, ultrasonic extraction
Frequency be 40kHz, power 500W.
Using above-mentioned preferred extracting method, the recovery rate of effective component Pseudo laric acid B can be further increased, is promoted
Rate may be up to 0.2%-0.3%.
The extracting method of the Herba Senecionis Scandentis extract is as follows:Climbing groundsel is put in 55-65 DEG C of insulating box dry 0.5-2h,
Grinding and sieving (preferably 30 meshes);2-4 is extracted at 55-65 DEG C with the 50-70% ethyl alcohol for being equivalent to 10-14 times of its quality
Secondary, extraction time is 1-3h every time, respectively combined extract and be condensed into medicinal extract (preferably relative density be 1.1-1.3 leaching
Cream);
It is preferred that climbing groundsel is put in 60 DEG C of insulating boxs dry 1h, 30 meshes are smashed it through;With being equivalent to 12 times of its quality
60% ethyl alcohol extracts 3 times at 60 DEG C, and extraction time is respectively 2h, 1.5h, 1h, combined extract and is condensed into relatively close respectively
Degree be 1.1-1.3 medicinal extract to get.
Using said extracted method, the recovery rate of effective component senecionine can be made to greatly improve, other have antibacterial function
The phenolic acid compound recovery rate of effect can also be promoted, so that the restraining and sterilizing bacteria effect in prescription is also improved simultaneously.
Magnolia cortex P.E be after Cortex Magnoliae Officinalis is crushed with after ethanol solution alcohol extracting through being concentrated to get.
Specifically, the extracting method of the Magnolia cortex P.E is as follows:By Cortex Magnoliae Officinalis fruit grinding and sieving (preferably 30 meshes),
It is extracted 2-4 times at 55-65 DEG C with the 50-70% ethyl alcohol for being equivalent to 8-12 times of its quality, extraction time is 1-3h every time, respectively
Combined extract and be condensed into medicinal extract (preferably relative density be 1.1-1.3 medicinal extract);
It is preferred that Cortex Magnoliae Officinalis fruit is smashed it through 30 meshes, extracted at 60 DEG C with 60% ethyl alcohol for being equivalent to 10 times of its quality
3 times, extraction time is respectively 2h, 1.5h, 1h, combined extract and is condensed into the medicinal extract that relative density is 1.1-1.3 respectively, i.e.,
?.
Using said extracted method, the recovery rate of effective component magnolol can be made to greatly improve, make the suppression in prescription
Bacterium bactericidal effect is also improved simultaneously.
Medical fluid of the present invention still further comprises solvent in addition to above-mentioned active constituent, i.e., the described medical fluid by activity at
Dispersion is formed in a solvent.It is preferred that the dosage of the solvent is 200-900 parts by weight.
Specifically, medical fluid of the present invention is used as solvent with ethanol water, water, propylene glycol, glycerine etc., with more advantageous
In dispersion of active ingredients, it is ensured that medical fluid/towel of going to the lavatory quality.
When the solvent is ethanol water, volumetric concentration is advisable in 50-75%, preferably 60-70%.
It further include spice additive in medical fluid of the present invention, the odor additive includes pure natural spice or artificial fragrant
Material.
Wherein, the pure natural spice is selected from one or more of elscholtiza, borneol, oriental wormwood, peppermint hydrosol and yellow wormwood artemisia;Institute
It states plants essential oil and is selected from Chinese torreya essential oil, mother chrysanthemum flower essential oil, daphne odera essential oil, pinecone essential oil, mugwort oil, thyme essential oil, You Jia
One or more of sharp essential oil, tea tree ethereal oil and camphor tree essential oil.
Preferably, various plants essential oils and chemical synthesis essence, especially Elsholtzia cilita essential oil, argy wormwood may be selected in the artificial flavors
Oil, daphne odera essential oil and camphor tree essential oil, such essential oil is preferably to be added medical fluid of the present invention, further to adjust gas
Taste increases effect.
The dosage of above-mentioned spice additive, which is subject to, can make the medical fluid form pleasant fragrance, when selection plants essential oil
When, ideal dosage is 0.1%-0.3%, can specifically be adjusted according to actual conditions.
Towel of the present invention of going to the lavatory is wet tissue or dry towel, and the base fabric is selected from non-woven fabrics or domestic paper, the domestic paper
It is preferred that wettable domestic paper.Wherein, domestic paper refers to paper for daily use, refer to for look after it is personal at home, it is outgoing it is equal used in all kinds of defend
Raw wiping paper, including roll toilet paper, extraction-type toilet paper, Boxed facial tissue, pocket face-tissue, paper handkerchief, napkin paper, wiping hand
Paper, kitchen towels.Wettable domestic paper refers to that wet strength is preferable in domestic paper, can wipe at home and not allow in the case where getting wet
Easily rupturable paper.
When the towel of going to the lavatory is wet tissue, non-woven fabrics or domestic paper is may be selected in the base fabric, i.e., the medical fluid is infiltrated institute
Stating base fabric can be obtained towel wet tissue of going to the lavatory.This field conventional technology can be used in the preparation method for towel wet tissue of going to the lavatory, in order to
Obtain the optimal towel wet tissue of going to the lavatory of effect, the present invention is preferably during towel wet tissue is gone to the lavatory in infiltration, use of the medical fluid with respect to base fabric
Amount is 4-6ml/g, after infiltration, drains the moisture for towel of going to the lavatory, reaches the wet tissue water content of this field routine.For
Medical fluid is set preferably to play antibacterial, disinfection, the infiltration amount that the present invention preferably controls final products herb liquid is 4.5-
5.5g/g being advisable.
When the towel of going to the lavatory is dry towel, domestic paper is may be selected in the base fabric, the needle slurry of the preferably described domestic paper
Usage amount is 85% or more, and moisture is less than 9.0%.
Alternatively, the index of the ideal domestic paper at least meets 3 of following index or more (preferably meeting):Thickness
For 0.05-0.07mm, longitudinal dry tensile strength is 2000-3200mN, and lateral dry tensile strength is 290-370mN, elongation 9%-11%,
2mm~5mm hole eye number≤6/m2, single layer transverse direction suction range is not less than 20mm/100s, and the double-deck transverse direction suction range is not less than
40mm/100s。
Preferably, the wettable domestic paper with a thickness of 0.05-0.06mm, longitudinal dry tensile strength is 2480-3000mN,
Lateral dry tensile strength is 290-320mN, elongation 10%-11%, 2mm~5mm hole eye number≤6/m2, single layer transverse direction suction range
Not less than 20mm/100s, the double-deck transverse direction suction range is not less than 40mm/100s.
The life stationery base fabric that the present invention can select further includes such as permanent wettable water paper handkerchief of peace product promise.
The present invention goes to the lavatory the medicine liquid spray the dry towel of towel to obtain the final product on base fabric (and can be described as body paper), the specific spray of medical fluid
The amount of spilling can be by those skilled in the art depending on the conventional selection of this field, foundation actual conditions, and medical fluid of the present invention exists
Fountain height in base fabric is preferably 0.006-0.008ml/g, and what this fountain height was prepared go to the lavatory, and towel medicine liquid spray is uniform, humidity
It is suitable for being easy to use.
In addition, above-mentioned base fabric has preferably covered one layer of smears, such base fabric softness moisturizing, while water imbibition on its surface
It is good, more skin-friendly strong with the towel water lock ability of going to the lavatory that this base fabric is prepared.The smears can be selected from commonly used in the art
Substance plays optimal effect in order to enable smears can preferably cooperate with medical fluid described herein, and the present invention is preferred
Above-mentioned smears is selected from one of moisturizer, softening agent, creams or a variety of, and (smears is opposite for its further preferred coating weight
In the mass percent dosage of base fabric) it is 18-25%.Wherein, the moisturizer be selected from glycerol, polyglycereol, transparent Bronsted acid sodium,
One or more of aloe extract.
Invention also provides the preparation methods of above-mentioned towel of going to the lavatory, as one of technical solution of the present invention, when described
When towel of going to the lavatory is wet tissue, preparation method specifically comprises the following steps:
(1) 8-12 parts of Cortex Dictamni extract, 12-18 parts of Cortex Pseudolaricis extract, 10-15 parts of Herba Senecionis Scandentis extract, Cortex Magnoliae Officinalis are taken
It is 6-10 parts of extract, spare;
(2) each component in step (1) is dissolved in partial solvent, is stirred evenly;
(3) step (2) acquired solution is filtered, deposit is removed, takes supernatant, further add solvent thereto, it is fixed
Hold to 700-900 parts;Or it is further added in the supernatant and adds solvent constant volume again after spice additive and disappear to get antibacterial
Poison liquid;
(4) by the antibacterial disinfection medical fluid infiltration base fabric to get.
Preferably, step (4) herb liquid is 4-6ml/g with respect to the dosage of base fabric.
Preferably, the solvent is 50-75% ethanol solution or water.
Wherein, step (2) is predissolve step, and the partial solvent preferably accounts for the 8-12% of total solvent volume, predissolve
The abundant dissolution for facilitating active constituent, improves the quality of medical fluid.
As another technical solution of the invention, when the towel of going to the lavatory is dry towel, preparation method specifically include as
Lower step:
(1) 8-12 parts of Cortex Dictamni extract, 12-18 parts of Cortex Pseudolaricis extract, 10-15 parts of Herba Senecionis Scandentis extract, Cortex Magnoliae Officinalis are taken
It is 6-10 parts of extract, spare;
(2) each component in step (1) is dissolved in partial solvent, is stirred evenly;
(3) step (2) acquired solution is filtered, deposit is removed, takes supernatant, further add solvent thereto, it is fixed
Hold to 200-400 parts;Or it is further added in the supernatant and adds solvent constant volume again after spice additive and disappear to get antibacterial
Poison liquid;
(4) by the antibacterial disinfection medical fluid be sprayed at scrim surfaces to get.
Fountain height of the medical fluid of the present invention in base fabric is preferably 0.006-0.008ml/g,
Preferably, the solvent is 50-75% ethanol solution or glycerine.
Step (2) is predissolve step, and the partial solvent preferably accounts for the 8-12% of total solvent volume, and predissolve facilitates
The abundant dissolution of active constituent, improves the quality of medical fluid.
Currently, life paper conversion mainly includes two processes:Preceding processing and post-processing.Preceding processing refers to that body paper produces, rear to add
Work refer to the body paper after cutting is embossed, the processing such as Amscomatic.The present invention is in order to enable final products are more soft wet
Profit, pro-skin sense is stronger, and each layer of paper handkerchief is tightly combined, and is easy to use, and in this application, has been especially added with completely new middle processing skill
Art, which is to carry out roller coating or spray treatment to body paper using smears before post-processing, in addition, changing existing
" being first embossed, rear to fold " mode, using completely new " first folding, rear to be embossed " mode.
Concrete operations are:In step (4), first base fabric is coated using smears, is then cut into base fabric specified
Breadth, then folded, be embossed, fold and embossing process in by the antibacterial disinfection medical fluid or antibacterial disinfection medical fluid
It is sprayed on the surface of base fabric with fragrance, finally product is packed, is sterilized.
The specification of towel of the present invention of going to the lavatory can be adjusted according to actual conditions, and optimal size is:10cm × 14cm, thickness
16 layers, white embossing, with the fragrance tasteless, the fragrant and a variety of different type of Chinese medicine is light.
Towel of the present invention of going to the lavatory has the following advantages that:
(1) Cortex Dictamni extract in the present invention, Cortex Pseudolaricis extract, Herba Senecionis Scandentis extract, four kinds of Magnolia cortex P.E at
It point is used in combination, there is heat-clearing and damp-drying drug, eliminate dampness with aromatics, restraining and sterilizing bacteria, can prevent microorganism infection, when use has cleaning, relaxes
Suitable, health-care effect.
(2) medical fluid tool of the invention is antibacterial, sterilization and antiinflammation, to skin and vaginal mucosa without any irritation and
Side effect, it is fragrant odour, easy to carry.
(3) go to the lavatory towel soft comfortable, good water absorption, the fungistatic effect prepared using medical fluid of the present invention is significant and has
The features such as easily disperse.
(4) the advantages that medical fluid of the present invention and towel of going to the lavatory are provided with low in cost, long shelf-life, high stability.
Detailed description of the invention
Fig. 1 is the preparation technology flow chart of towel dry towel of the invention of going to the lavatory.
Specific embodiment
The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention..
All raw materials of the present invention are known commercially available product, and the detection method being related to or operation are such as without special
Explanation is the common detection methods or operation of this field.Cortex Dictamni extract involved in following embodiment, a thousand li light extraction
Object, Cortex Pseudolaricis extract, Magnolia cortex P.E extract by the following method.
Cortex Dictamni extract:Cortex dictamni is smashed it through into 30 meshes, according to 1:18 solid-liquid ratio (g:Ml), volume fraction is used
90% EtOH Sonicate extracts 85min, and concentrated extracting solution is at the medicinal extract of relative density 1.1~1.3 to get, wherein ultrasonic extraction
Frequency be 40kHz, power 500W.
Herba Senecionis Scandentis extract:Climbing groundsel is put in 60 DEG C of insulating boxs dry 1h, smashes it through 30 meshes;With being equivalent to it
12 times of 60% ethyl alcohol of quality extracts 3 times at 60 DEG C, and extraction time is respectively 2h, 1.5h, 1h, combined extract and is concentrated respectively
At relative density be 1.1-1.3 medicinal extract to get.
Cortex Pseudolaricis extract:Golden Larch Bark is smashed it through into 30 meshes, according to 1:12 solid-liquid ratio (g:Ml), volume fraction is used
90% EtOH Sonicate extracts 20min, concentrated extracting solution at the medicinal extract that relative density is 1.1-1.3 to get, wherein ultrasound mentions
The frequency taken is 40kHz, power 500W.
Magnolia cortex P.E:Cortex Magnoliae Officinalis fruit is smashed it through into 30 meshes, with being equivalent to 60% ethyl alcohol of 10 times of its quality 60
It is extracted 3 times at DEG C, extraction time is respectively 2h, 1.5h, 1h, respectively combined extract and to be condensed into relative density be 1.1-1.3
Medicinal extract to get.
Although a kind of above-mentioned specific embodiment for being only exemplified by each extract, it will be appreciated by those skilled in the art that
Be be not limited to other extracting methods (method especially in the limited range of the present invention) of ad hoc fashion similarly can be with
It realizes essentially identical extraction effect, can be used for realizing the present invention, this is no longer particularly limited.
Only as explaining, such as Cortex Dictamni extract obtained may be equally applied to the present invention in accordance with the following methods:
Cortex Dictamni extract:Cortex dictamni is smashed it through into 30 meshes, according to 1:16 or 1:19 solid-liquid ratio (g:Ml), body is used
Fraction 88 or 92% EtOH Sonicate extract 83-87min, concentrated extracting solution at the medicinal extract of relative density 1.1~1.3 to get,
Wherein, the frequency of ultrasonic extraction is 60kHz, power 400W.
The parameter of wettable domestic paper used in following embodiment is as follows:With a thickness of 0.05-0.06mm, longitudinal dry tensile strength
For 2480-3000mN, lateral dry tensile strength is 290-320mN, elongation 10%-11%, 2mm~5mm hole eye number≤6/m2, single
The lateral suction range of layer is not less than 20mm/100s, and the double-deck transverse direction suction range is not less than 40mm/100s.
It will be appreciated by persons skilled in the art that other suitable paper products can in addition to above-mentioned preferred wettable domestic paper
It is equally used for realizing the present invention.
Embodiment 1
Present embodiments provide a kind of with antibacterial, disinfection towel of going to the lavatory, which is wet tissue, towel Chinese medicine of going to the lavatory
The infiltration amount of liquid is 4-6g/g;Wherein the base fabric is non-woven fabrics;The specific prescription of the medical fluid is as follows:Cortex Dictamni extract 8
Part, 12 parts of Cortex Pseudolaricis extract, 10 parts of Herba Senecionis Scandentis extract, 6 parts of Magnolia cortex P.E, 1 part of daphne odera essential oil, 800 parts of water.
Embodiment 2
Present embodiments provide a kind of with antibacterial, disinfection towel of going to the lavatory, which is dry towel, the towel of going to the lavatory
Base fabric by having adsorbed antibacterial disinfection medical fluid is formed, and the base fabric is wettable domestic paper;The specific prescription of the medical fluid is as follows:It is white
10 parts of fresh hide extract, 15 parts of Cortex Pseudolaricis extract, 12 parts of Herba Senecionis Scandentis extract, 8 parts of Magnolia cortex P.E, 1 part of daphne odera essential oil,
60% 300 parts of ethyl alcohol, medical fluid are 0.006-0.008ml/g to the fountain height of wettable domestic paper.
Embodiment 3
Present embodiments provide a kind of with antibacterial, disinfection towel of going to the lavatory, which is dry towel, the towel of going to the lavatory
Base fabric by having adsorbed antibacterial disinfection medical fluid is formed;The base fabric is wettable domestic paper;The specific prescription of the medical fluid is as follows:It is white
12 parts of fresh hide extract, 18 parts of Cortex Pseudolaricis extract, 15 parts of Herba Senecionis Scandentis extract, 10 parts of Magnolia cortex P.E, 300 parts of glycerine,
Medical fluid is 0.006-0.008ml/g to the fountain height of wettable domestic paper.
Embodiment 4
Present embodiments provide a kind of with antibacterial, disinfection towel of going to the lavatory, which is dry towel, the towel of going to the lavatory
Base fabric by having adsorbed antibacterial disinfection medical fluid is formed;The base fabric is wettable domestic paper;The specific prescription of the medical fluid is as follows:It is white
10 parts of fresh hide extract, 16 parts of Cortex Pseudolaricis extract, 15 parts of Herba Senecionis Scandentis extract, 9 parts of Magnolia cortex P.E, 70% 300 parts of ethyl alcohol,
Antibacterial disinfection medical fluid is 0.006-0.008ml/g to the fountain height of wettable domestic paper.
Embodiment 5
A kind of method prepared described in embodiment 1 with antibacterial, disinfection towel of going to the lavatory is present embodiments provided, specifically
Include the following steps:
(1) Cortex Dictamni extract, Herba Senecionis Scandentis extract, Cortex Pseudolaricis extract, Magnolia cortex P.E are dissolved in 80 parts of water, are stirred
It mixes uniformly;
(2) step (1) acquired solution is filtered, deposit is removed, takes supernatant, daphne odera essential oil is added thereto, so
After add remaining water, be uniformly mixed up to antibacterial disinfection medical fluid;
(3) non-woven fabrics that the antibacterial disinfection medical fluid infiltration is cut into suitable dimension, is packed to obtain the final product.
Embodiment 6
A kind of method prepared described in embodiment 2 with antibacterial, disinfection towel of going to the lavatory is present embodiments provided, specifically
Include the following steps (as shown in Figure 1):
(1) Cortex Dictamni extract, Herba Senecionis Scandentis extract, Cortex Pseudolaricis extract, Magnolia cortex P.E are dissolved in 30 part of 60% second
In alcohol, stir evenly;
(2) step (1) acquired solution is filtered, deposit is removed, takes supernatant, daphne odera essential oil is added thereto, is mended
Add remaining ethyl alcohol, is uniformly mixed up to antibacterial disinfection medical fluid;
(3) first wettable domestic paper (and can claim body paper) is coated with using rolling method using glycerol (coating weight 20%), then
Paper product is cut into 10cm × 14cm breadth, then folded, be embossed, by the antibacterial disinfection in folding and embossing process
Medical fluid (fountain height 0.006-0.008ml/g) is sprayed on the surface of paper product, is finally packed to product, ethylene oxide sterilizing
To obtain the final product.
Embodiment 7
A kind of method prepared described in embodiment 3 with antibacterial, disinfection towel of going to the lavatory is present embodiments provided, specifically
Include the following steps:
(1) Cortex Dictamni extract, Herba Senecionis Scandentis extract, Cortex Pseudolaricis extract, Magnolia cortex P.E are dissolved in 36 parts of glycerine
In, it stirs evenly;
(2) step (1) acquired solution is filtered, deposit is removed, takes supernatant, add remaining glycerine, is uniformly mixed
Up to antibacterial disinfection medical fluid;
(3) first wettable domestic paper is coated with using polyglycereol (coating weight 18%) using rolling method, then cuts paper product
It at 10cm × 14cm breadth, then folded, be embossed, be sprayed on the antibacterial disinfection medical fluid in embossing process folding
The surface (fountain height 0.006-0.008ml/g) of paper product, finally product is packed, ethylene oxide sterilizing to obtain the final product.
Embodiment 8
A kind of method prepared described in embodiment 4 with antibacterial, disinfection towel of going to the lavatory is present embodiments provided, specifically
Include the following steps:
(1) Cortex Dictamni extract, Herba Senecionis Scandentis extract, Cortex Pseudolaricis extract, Magnolia cortex P.E are dissolved in 24 part of 70% second
In alcohol, stir evenly;
(2) step (1) acquired solution is filtered, deposit is removed, takes supernatant, add remaining ethyl alcohol, is uniformly mixed i.e.
Obtain antibacterial disinfection medical fluid;
(3) first wettable domestic paper is used using softening agent SME-4 (polyoxyethylene stearic acid ester, coating weight 25%) and is sprayed
Method coating, then cuts into 10cm × 14cm breadth for paper product, is then folded, is embossed, will in folding and embossing process
The antibacterial disinfection medical fluid is sprayed on the surface (fountain height 0.006-0.008ml/g) of paper product, is finally packed, is gone out to product
Bacterium to obtain the final product.
Below by way of fungistatic effect, the stability etc. for testing medical fluid of the present invention and towel of going to the lavatory, the present invention is protected
Technical solution be further described.
The experiment of one fungistatic effect of experimental example
1, medical fluid fungistatic effect is tested
1.1 experiment reagents (see Table 1 for details):
Table 1:
Licorice, camomile extract and aloe extract etc. can be right by commercially available in above-mentioned control group
Preparation according to Fructus Gleditsiae Abnormalis extract in group 6 can refer to China application CN103340816.
1.2 experimental method
Experimental strain:Staphylococcus aureus, Candida albicans, Escherichia coli, Pseudomonas aeruginosa, hemolytic streptococcus;Tool
The reference of body experimental procedure《15979-2002 disposable sanitary articles sanitary standard》Regulation.
1.3 experimental result
Experimental result is shown in Table 2:
Table 2:Bacteriostasis rate (%)
Above-mentioned experiment is repeated with the medical fluid of other embodiments of the present invention, obtains essentially identical experiment conclusion.
2, wet tissue fungistatic effect is tested
2.1 experiment reagents (see Table 3 for details):
Table 3:
Experimental group 1 | The preparation-obtained wet tissue of embodiment 5 (the infiltration amount of medical fluid is 5g/g, and liquid formula is with embodiment 1) |
Compare blank group | With experimental group 1, difference is only that wet tissue preparation method:Non-woven fabrics is infiltrated using physiological saline |
Control group 1 | With experimental group 1, difference is only that wet tissue preparation method:Using the active constituent of control group 1 |
Control group 2 | With experimental group 1, difference is only that wet tissue preparation method:Using the active constituent of control group 2 |
Control group 3 | With experimental group 1, difference is only that wet tissue preparation method:Using the active constituent of control group 3 |
Control group 4 | With experimental group 1, difference is only that wet tissue preparation method:Using the active constituent of control group 4 |
Control group 5 | With experimental group 1, difference is only that wet tissue preparation method:Using the active constituent of control group 5 |
Control group 6 | With experimental group 1, difference is only that wet tissue preparation method:Using the active constituent of control group 6 |
2.2 experimental method:
With 2.1.
2.3 experimental result
See Table 4 for details for experimental result.
Table 4:Bacteriostasis rate (%)
3, dry towel fungistatic effect experiment
3.1 experiment reagents (see Table 5 for details):
Table 5:
3.2 experimental method:With 2.2;
3.3 experimental result
See Table 6 for details for experimental result.
Table 6:Bacteriostasis rate (%)
4, wet tissue and the experiment of the long-time stability of dry towel
Experimental subjects:Table 3 after placing 3,6,12 and 24 months after preparation respectively and wet tissue and dry towel in table 5;
Experimental method:With 2.2 and 3.2;
Experimental result is shown in Table 7.
Table 7:Bacteriostasis rate (%)
Two wet tissue of experimental example, dry towel skin irritation test
Laboratory sample:Dry towel in wet tissue and table 2 in table 1
Experimental method:Experiment before rabbit back spinal diamond wool is cut for 24 hours, unhairing range or so give 5cm × 5cm, one
For testing, skin is cleaned for compareing, using warm water in side for side, then wipes laboratory sample on a side test skin,
Wiping 1 time daily, 1h observes skin wound repair after wiping, and continuous wiping 30 days records experimental result.
Experimental result:As shown in table 8.
8 skin irritation test result of table:
Three wet tissue of experimental example, the experiment of dry towel vaginal irritation
Laboratory sample:Dry towel in wet tissue and table 2 in table 1
Experimental method:SD rat is taken, female, regular grade, weight 220-240g is randomly divided into 16 groups, every group 4.Reference
3.8 in disinfection technology standard (third edition) 1999.11, dry towel, wet tissue are placed in animal intravaginal, contacted with vagina mucosa
2h, puts to death animal after 12h, takes out vagina local organization, and observation is whether there is or not congested, oedema phenomenon, referring to disinfection technology standard (the
Three editions) the standards of grading scoring of skin wound repair intensity and skin irritatin strength grading in 1999.11, it carries out to vagina mucosa
The evaluation of stimulus intensity.
Experimental result:It is shown in Table 9.
9 vaginal irritation experimental result of table:
Wet tissue of the present invention, dry towel are 0 to rat vagina mucosal irritation reaction top mean value, belong to nonirritant,
Shelf-life is 36 months or more.
Experimental example four is gone to the lavatory towel comprehensive quality test experiments
1, by carrying out test discovery to towel of going to the lavatory described in embodiment 6~8, the towel of going to the lavatory being related in above-described embodiment
Dry towel can reach index as shown in table 10, and properties are superior to GB/T 20808-2011 to the regulation of super soft paper.
It goes to the lavatory described in 10 embodiment 6-8 of table the product index of the dry towel of towel
2, to embodiment 6 go to the lavatory towel and common commercially available towel products compare, three control groups, control group are set
The 1 nose noble's face tissue produced for Japanese king's paper industry, control group 2 is a tissue of Ni Piao company production, and control group 3 is
Heng An group heart chief minister's seal tea family of languages column paper handkerchief, as a result as shown in table 11.
Table 11 is gone to the lavatory towel product actual measurement physical index and correlation data
As can be seen from Table 11, the present invention goes to the lavatory, and towel moisture content is suitable, and pliability is good, and has good dry drawing
Power and wet tensile strength, entire product sense of touch is soft and moist, and pro-skin sense is strong.
Experimental example five is gone to the lavatory towel material test experiments
The present invention further compared going to the lavatory the material of towel and conventional paper handkerchief, and specific targets are as follows:
1, body-sensing
Body-sensing refers to comfort when consumer's physical examination product, and the comfort of product is better, and body-sensing is better.Material
Body-sensing comfort be realized by improving 3 indexs of moisture feeling of the flexibility of paper, surface sophistication and paper, and then reach with
Nowadays the domestic paper that women generally uses is compared, and has apparent sense of touch otherness.
(1) flexibility
The pliability of domestic paper includes bulk softness and Surface softness.Bulk softness refers to when people with the hands squeeze
The softness of paper can be experienced when platen towel;Surface softness refers to finger tip slight amount, and touches paper back and forth and felt
Softness by paper.According to GB/T 20808-2011 to the regulation of super soft paper, single-part stationery pliability is necessary≤40mN.
(2) surface sophistication
Currently without specific detection means, mainly by user's finger tip slight amount, and paper is touched back and forth and is felt
Judged by the softness of paper, belongs to an importance in body-sensing.
(3) moisture feeling
Moisture feeling belongs to the new concept in domestic paper, is put forward for the first time for the application.According to GB/T 20808-2011 to super soft paper
Regulation, delivery moisture be≤9%.
2, water imbibition
Mainly measured by lateral suction range, according to GB/T 20808-2011 to the regulation of super soft paper, single-part stationery
Lateral suction range is greater than 20mm/100s.
3, breaking up property
For tissue Related product, breaking up property is mainly influenced by the additive amount of wet strength agent.Good paper product can reach
It abandons after to use in closestool, does not block closestool and sewer, it is degradable, it is free from environmental pollution.
4, toughness
Lateral tensile index and longitudinal wet tensile index are better than GB/T 20808-2011 to the regulation of super soft paper, to reach
To that will not be broken easily when body paper normal use use, deform.
It is found by comparison, its pliability of currently marketed paper handkerchief is of the present invention small generally between 38-40mN
Solution its pliability of towel is 30 ± 2mN, belongs to the high-class product in super soft paper;The moisture of paper handkerchief is commonly 7% or so on Vehicles Collected from Market,
The present invention goes to the lavatory, and towel water conservation moisture pick-up properties is good, and paper handkerchief moisture content remains between 15-18%, and exquisiteness is good, and sense of touch is soft
Profit, pro-skin sense are strong;In addition, the present invention goes to the lavatory, the water imbibition of towel also meets national standard, and has good easily disperse, uses
After abandon in closestool, do not block closestool and sewer, it is degradable, it is free from environmental pollution.
In addition to this, table 12 has also listed other differences of go to the lavatory towel and conventional paper handkerchief of the invention.
Table 12 is gone to the lavatory the difference of towel and conventional paper handkerchief
Experimental example six is gone to the lavatory towel market questionnaire investigation
The present invention has carried out questionnaire investigation to towel of going to the lavatory simultaneously, as a result as shown in table 13:There is 70.29% women to think very
Like going to the lavatory the texture of towel, 26.43% women waits and see.Generally speaking, the public to the degree of recognition of product close to 80%,
There are extraordinary market prospects.
Degree of recognition of 13 public of table to towel product of going to the lavatory at this stage
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this
The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, this is to this
It is for the technical staff of field it will be apparent that these changes and improvements all fall within the protetion scope of the claimed invention.This hair
Bright claimed range is defined by the appending claims and its equivalent thereof.
Claims (21)
1. a kind of with antibacterial, disinfection towel of going to the lavatory, it is characterised in that:The towel of going to the lavatory is by having adsorbed antibacterial disinfection medical fluid
Base fabric formed;By weight, the active constituent of the medical fluid is as follows:8-12 parts of Cortex Dictamni extract, Cortex Pseudolaricis extract
12-18 parts, 10-15 parts of Herba Senecionis Scandentis extract, 6-10 parts of Magnolia cortex P.E;
The extracting method of the Cortex Dictamni extract is as follows:By cortex dictamni grinding and sieving, according to 1:15-1:20 solid-liquid ratio,
Extract 80-90min with the EtOH Sonicate of volume fraction 85%-95%, concentrated extracting solution at medicinal extract to get;
The extracting method of the Cortex Pseudolaricis extract is as follows:By Golden Larch Bark grinding and sieving, according to 1:10-1:18 solid-liquid ratio,
Extract 15-25min with the EtOH Sonicate of volume fraction 80%-90%, concentrated extracting solution at medicinal extract to get;
The extracting method of the Herba Senecionis Scandentis extract is as follows:Climbing groundsel is put in 55-65 DEG C of insulating box dry 0.5-2h, is crushed
After be sieved;It is extracted 2-4 times at 55-65 DEG C with the 50-70% ethyl alcohol for being equivalent to 10-14 times of its quality, extraction time is every time
1-3h combined extract and is condensed into medicinal extract respectively;
The extracting method of the Magnolia cortex P.E is as follows:By Cortex Magnoliae Officinalis fruit grinding and sieving, with being equivalent to 8-12 times of its quality
50-70% ethyl alcohol extracts 2-4 times at 55-65 DEG C, and extraction time is 1-3h every time, combined extract and is condensed into leaching respectively
Cream.
2. towel of going to the lavatory as described in claim 1, it is characterised in that:By weight, the active constituent of the medical fluid is as follows:It is white
10 parts of fresh hide extract, 15 parts of Cortex Pseudolaricis extract, 12 parts of Herba Senecionis Scandentis extract, 8 parts of Magnolia cortex P.E.
3. towel of going to the lavatory as claimed in claim 1 or 2, it is characterised in that:The extracting method of the Cortex Dictamni extract is as follows:It will
Cortex dictamni smashes it through 30 meshes, according to 1:16-1:19 solid-liquid ratio is extracted with the EtOH Sonicate of volume fraction 88%-92%
83-87min, concentrated extracting solution at the medicinal extract of relative density 1.1-1.3 to get;
And/or:
The extracting method of the Cortex Pseudolaricis extract is as follows:Golden Larch Bark is smashed it through into 30 meshes, according to 1:12 solid-liquid ratio is used
The EtOH Sonicate of volume fraction 88%-92% extracts 18-22min, and concentrated extracting solution is the medicinal extract of 1.1-1.3 at relative density,
To obtain the final product;
And/or:
The extracting method of the Herba Senecionis Scandentis extract is as follows:Climbing groundsel is put in 60 DEG C of insulating boxs dry 1h, smashes it through 30
Mesh;It is extracted 3 times at 60 DEG C with 12 times of 60% ethyl alcohol of its quality is equivalent to, extraction time is respectively 2h, 1.5h, 1h, difference
Combined extract and be condensed into relative density be 1.1-1.3 medicinal extract to get;
And/or:
The extracting method of the Magnolia cortex P.E is as follows:Cortex Magnoliae Officinalis fruit is smashed it through into 30 meshes, with being equivalent to 10 times of its quality
60% ethyl alcohol extracted 3 times at 60 DEG C, extraction time is respectively 2h, 1.5h, 1h, combined extract and is condensed into opposite respectively
Density be 1.1-1.3 medicinal extract to get.
4. towel of going to the lavatory as claimed in claim 1 or 2, it is characterised in that:The medical fluid with ethanol water, water, propylene glycol or
Glycerine is as solvent.
5. towel of going to the lavatory as claimed in claim 4, it is characterised in that:The dosage of the solvent is 200-900 parts by weight.
6. towel of going to the lavatory as claimed in claim 3, it is characterised in that:The medical fluid is with ethanol water, water, propylene glycol or the third three
Alcohol is as solvent.
7. towel of going to the lavatory as claimed in claim 6, it is characterised in that:The dosage of the solvent is 200-900 parts by weight.
8. the towel of going to the lavatory as described in any one of claim 1,2,6, it is characterised in that:It further include fragrance addition in the medical fluid
Agent, the spice additive include pure natural spice or artificial flavors.
9. towel of going to the lavatory as claimed in claim 3, it is characterised in that:It further include spice additive in the medical fluid, the fragrance
Additive includes pure natural spice or artificial flavors.
10. towel of going to the lavatory as claimed in claim 4, it is characterised in that:It further include spice additive in the medical fluid, the fragrance
Additive includes pure natural spice or artificial flavors.
11. towel of going to the lavatory as claimed in claim 8, it is characterised in that:The pure natural spice is selected from elscholtiza, borneol, oriental wormwood, thin
One or more of lotus hydrosol and yellow wormwood artemisia;The artificial flavors include plants essential oil and chemical synthesis essence;The plant essence
Oil is selected from Chinese torreya essential oil, mother chrysanthemum flower essential oil, daphne odera essential oil, pinecone essential oil, mugwort oil, thyme essential oil, eucalyptus quintessence oil, tea
Set one or more of essential oil and camphor tree essential oil.
12. the towel of going to the lavatory as described in any one of claim 1,2,6,9,10,11, it is characterised in that:The towel of going to the lavatory is wet
Towel or dry towel.
13. towel of going to the lavatory as claimed in claim 3, it is characterised in that:The towel of going to the lavatory is wet tissue or dry towel.
14. towel of going to the lavatory as claimed in claim 4, it is characterised in that:The towel of going to the lavatory is wet tissue or dry towel.
15. towel of going to the lavatory as claimed in claim 8, it is characterised in that:The towel of going to the lavatory is wet tissue or dry towel.
16. towel of going to the lavatory as described in claim 1, it is characterised in that:The base fabric is selected from non-woven fabrics or domestic paper.
17. towel of going to the lavatory as claimed in claim 16, it is characterised in that:When the towel of going to the lavatory is wet tissue, base fabric is selected from non-woven fabrics
Or domestic paper, when the towel of going to the lavatory is dry towel, base fabric is selected from/domestic paper.
18. towel of going to the lavatory as claimed in claim 12, it is characterised in that:The base fabric is selected from non-woven fabrics or domestic paper.
19. towel of going to the lavatory as claimed in claim 18, it is characterised in that:When the towel of going to the lavatory is wet tissue, base fabric is selected from non-woven fabrics
Or domestic paper, when the towel of going to the lavatory is dry towel, base fabric is selected from domestic paper.
20. a kind of preparation method for towel of going to the lavatory, it is characterised in that:It is described go to the lavatory towel be wet tissue, preparation method specifically include as
Lower step:
(1) 8-12 parts of Cortex Dictamni extract, 12-18 parts of Cortex Pseudolaricis extract, 10-15 parts of Herba Senecionis Scandentis extract, Cortex Magnoliae Officinalis is taken to extract
It is 6-10 parts of object, spare;
(2) each component in step (1) is dissolved in partial solvent, is stirred evenly;
(3) step (2) acquired solution is filtered, deposit is removed, takes supernatant, further add solvent thereto, be settled to
700-900 parts;Or it is further added in the supernatant after spice additive and adds solvent constant volume again to get antibacterial disinfectant
Liquid;
(4) by the antibacterial disinfection medical fluid infiltration base fabric to get;
Or, the towel of going to the lavatory is dry towel, preparation method specifically comprises the following steps:
(1) 8-12 parts of Cortex Dictamni extract, 12-18 parts of Cortex Pseudolaricis extract, 10-15 parts of Herba Senecionis Scandentis extract, Cortex Magnoliae Officinalis is taken to extract
It is 6-10 parts of object, spare;
(2) each component in step (1) is dissolved in partial solvent, is stirred evenly;
(3) step (2) acquired solution is filtered, deposit is removed, takes supernatant, further add solvent thereto, be settled to
200-400 parts;Or it is further added in the supernatant after spice additive and adds solvent constant volume again to get antibacterial disinfectant
Liquid;
(4) by the antibacterial disinfection medical fluid be sprayed at scrim surfaces to get.
21. the preparation method for towel of going to the lavatory as claimed in claim 20, it is characterised in that:When preparing dry towel, step (4) it is specific
Operation is:First base fabric is coated using smears, then base fabric is cut into specified breadth, then folded, pressed
The antibacterial disinfection medical fluid or antibacterial disinfection medical fluid and fragrance are sprayed on the surface of base fabric by flower in folding and embossing process,
Finally product is packed, is sterilized to obtain the final product.
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CN107651484A (en) * | 2016-08-25 | 2018-02-02 | 佛山市瑞信无纺布有限公司 | A kind of auto-folder reel of non-woven fabrics |
WO2018039849A1 (en) * | 2016-08-29 | 2018-03-08 | 张柳 | Disinfectant |
CN107952104A (en) * | 2017-12-04 | 2018-04-24 | 株洲千金药业股份有限公司 | A kind of feminine hygiene articles for preventing menstruation infection and preparation method thereof |
CN107753998A (en) * | 2017-12-04 | 2018-03-06 | 株洲千金药业股份有限公司 | A kind of feminine hygiene articles of bacteriostatic and disease prevention and preparation method thereof |
CN112514922A (en) * | 2020-12-03 | 2021-03-19 | 杭州象外环保科技有限公司 | Purifier essential oil with sterilization function and preparation method thereof |
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CN1300623A (en) * | 1999-12-20 | 2001-06-27 | 张发平 | Chinese patent medicine |
CN2707226Y (en) * | 2004-07-13 | 2005-07-06 | 林道兴 | Convenient and practical sanitary napkin |
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CN2201082Y (en) * | 1994-08-22 | 1995-06-21 | 王昌珍 | Napkins for sexual intercourse |
CN1300623A (en) * | 1999-12-20 | 2001-06-27 | 张发平 | Chinese patent medicine |
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