CN105520758B - A closure device for patent foramen ovale or small atrial septal defect - Google Patents
A closure device for patent foramen ovale or small atrial septal defect Download PDFInfo
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- CN105520758B CN105520758B CN201610035276.2A CN201610035276A CN105520758B CN 105520758 B CN105520758 B CN 105520758B CN 201610035276 A CN201610035276 A CN 201610035276A CN 105520758 B CN105520758 B CN 105520758B
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- septal defect
- closure
- atrial septal
- foramen ovale
- patent foramen
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- 208000035478 Interatrial communication Diseases 0.000 title claims abstract description 55
- 206010003664 atrial septal defect Diseases 0.000 title claims abstract description 55
- 208000013914 atrial heart septal defect Diseases 0.000 title claims abstract description 54
- 208000008883 Patent Foramen Ovale Diseases 0.000 title claims abstract 15
- 230000002093 peripheral effect Effects 0.000 claims abstract 3
- 239000007769 metal material Substances 0.000 claims description 10
- 239000002184 metal Substances 0.000 claims description 5
- 229910052751 metal Inorganic materials 0.000 claims description 5
- 229910000906 Bronze Inorganic materials 0.000 claims description 3
- 229910000639 Spring steel Inorganic materials 0.000 claims description 3
- 239000010974 bronze Substances 0.000 claims description 3
- 229910001000 nickel titanium Inorganic materials 0.000 claims description 3
- 229910052790 beryllium Inorganic materials 0.000 claims 1
- ATBAMAFKBVZNFJ-UHFFFAOYSA-N beryllium atom Chemical compound [Be] ATBAMAFKBVZNFJ-UHFFFAOYSA-N 0.000 claims 1
- KUNSUQLRTQLHQQ-UHFFFAOYSA-N copper tin Chemical compound [Cu].[Sn] KUNSUQLRTQLHQQ-UHFFFAOYSA-N 0.000 claims 1
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 238000002513 implantation Methods 0.000 abstract 1
- 210000004491 foramen ovale Anatomy 0.000 description 16
- 230000004308 accommodation Effects 0.000 description 8
- 230000007547 defect Effects 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 210000004027 cell Anatomy 0.000 description 4
- 210000002837 heart atrium Anatomy 0.000 description 4
- 230000001605 fetal effect Effects 0.000 description 3
- 229910045601 alloy Inorganic materials 0.000 description 2
- 239000000956 alloy Substances 0.000 description 2
- 210000003157 atrial septum Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- KHYBPSFKEHXSLX-UHFFFAOYSA-N iminotitanium Chemical compound [Ti]=N KHYBPSFKEHXSLX-UHFFFAOYSA-N 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 210000003141 lower extremity Anatomy 0.000 description 2
- 238000011017 operating method Methods 0.000 description 2
- 230000002980 postoperative effect Effects 0.000 description 2
- 238000002601 radiography Methods 0.000 description 2
- 238000004064 recycling Methods 0.000 description 2
- 210000001364 upper extremity Anatomy 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 208000002330 Congenital Heart Defects Diseases 0.000 description 1
- 229910000863 Ferronickel Inorganic materials 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- VHHVGPDQBHJHFB-UHFFFAOYSA-N [Ti].[Cr].[Ni] Chemical compound [Ti].[Cr].[Ni] VHHVGPDQBHJHFB-UHFFFAOYSA-N 0.000 description 1
- 208000033571 alveolar capillary dysplasia with misalignment of pulmonary veins Diseases 0.000 description 1
- 210000001742 aqueous humor Anatomy 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 206010008118 cerebral infarction Diseases 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 208000028831 congenital heart disease Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000013020 embryo development Effects 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 208000025339 heart septal defect Diseases 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 201000007119 infective endocarditis Diseases 0.000 description 1
- 210000005246 left atrium Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000036244 malformation Effects 0.000 description 1
- 208000004594 persistent fetal circulation syndrome Diseases 0.000 description 1
- 230000036593 pulmonary vascular resistance Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 210000005245 right atrium Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00601—Implements entirely comprised between the two sides of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00623—Introducing or retrieving devices therefor
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Abstract
本发明属于植入人体的医疗器械领域，具体涉及一种卵圆孔未闭或小房间隔缺损闭合装置及一种卵圆孔未闭或小房间隔缺损闭合装置的输送装置。所述卵圆孔未闭或小房间隔缺损闭合装置包括闭合单元，所述闭合单元包括两个闭合器，所述两个闭合器相对设置；所述闭合器端部为嵌入部，所述嵌入部为卷曲状，可嵌入卵圆孔未闭或房间隔缺损处周侧；所述输送装置包括推送鞘管及一闭合器容纳装置，所述闭合器容纳装置置于所述推送鞘管内，所述第一闭合器及第二闭合器在所述闭合器容纳装置内。本发明的有益效果：具有置入装置小，易定位，可反复释放回收，进而实现确保在准确设置闭合器的基础上，阻断房水平分流。
The invention belongs to the field of medical devices implanted in the human body, in particular to a patent foramen ovale or small atrial septal defect closing device and a delivery device for a patent foramen ovale or small atrial septal defect closing device. The patent foramen ovale or small atrial septal defect closing device includes a closing unit, and the closing unit includes two closing devices, and the two closing devices are arranged oppositely; the end of the closing device is an embedded part, and the embedded part is The portion is curled and can be embedded in the peripheral side of the patent foramen ovale or atrial septal defect; the delivery device includes a pusher sheath and a occluder accommodating device, and the occluder accommodating device is placed in the pusher sheath, so The first closer and the second closer are in the closer accommodating device. The beneficial effects of the invention are as follows: the implantation device is small, easy to locate, and can be repeatedly released and recovered, thereby ensuring that the horizontal shunt of the room can be blocked on the basis of accurately setting the closure device.
Description
Technical field
The invention belongs to be implanted into the medical instruments field of human body, and in particular to a kind of acleistocardia or Small Atrial Septal Defect
Closing device.
Background technique
Oval foramen (Patent foramen oval, PFO) is the normal channel of the blood of fetal period, is a check valve
Door, its role is to fetal periods, and room blood to be made to flow to atrium sinistrum from atrium dextrum by oval foramen, normal to guarantee
Fetal circulation.After breathing occurs in fetal birth, as pulmonary vascular resistance reduces, oval foramen one-way cock is closed, room horizontal traffic
It disappears.But in normal adult crowd, there are about 1/3 Adult Groups oval foramens to be not off, and still retains a small aqueous humor and divides equally
Stream (is less than 5mm, be greater than 5mm and be known as atrial septal defect).Under normal circumstances, such crowd due to oval foramen shunt volume it is few, both
It is asymptomatic, also without long term complication.But at present evidence show, in this part population, occur infectious endocarditis and in it is old
The risk that cerebral infarction occurs for the term is higher than normal population.
Atrial septal defect (Atrial septal defect, ASD) is a kind of common congenital heart disease, is atrial septum
Occur exception in embryo development procedure, causes to leave hole between left and right atrium.Atrial septal defect can individually occur, can also be with
Other kinds of cardiovascular malformation is simultaneously deposited.Most atrial septal defect diameters are greater than 5mm, larger greater than 5mm for diameter at present
Atrial septal defect fit through surgical operation or minimally invasive transcatheter operative treatment, but surgery operating wound is big, operation risk
Height, post-operative recovery time is long, and transcatheter operation then needs to place a biggish metal atrial septal defect plugging device in vivo.
Due to internal cardiac structures complexity, postoperative short-term and the occurrence risk at a specified future date that may all will increase complication, and biggish envelope are intervened
Stifled device is placed in heart, and many patients are not easily accepted by, and furthermore transcatheter is difficult to release recycling repeatedly.
Summary of the invention
For deficiency present in background technique, the purpose of the present invention is to provide a kind of acleistocardia or cubicle every
Defect closing device, for treating the acleistocardia or atrial septal defect of 1-5mm.
Technical scheme is as follows: a kind of acleistocardia or Small Atrial Septal Defect closing device, the oval foramen
Patent or Small Atrial Septal Defect closing device include a closed cell, and the closed cell end is embedded division, the embedded division
To be curly, side at embeddable acleistocardia or Small Atrial Septal Defect.
Further, the closed cell includes two closers, and described two closers are oppositely arranged；
The closer includes an extension and an embedded division, and described two closers are connected by extension, and two prolong
The junction of extending portion connects a delivery guidewire jointly, and the embedded division is embedded in side at acleistocardia or Small Atrial Septal Defect,
Position embedded by described two embedded divisions is opposite.
Further, the extension is elastic metallic material；The embedded division is memory metal material.
Further, the elastic metallic material is beryllium-bronze or spring steel；The memory metal material is Ni-Ti conjunction
Gold.
The conveying device of a kind of acleistocardia or Small Atrial Septal Defect closing device, for conveying above-mentioned oval foramen not
It closes or Small Atrial Septal Defect closing device, the conveying device includes pushing sheath tube and a closer storing apparatus, the closure
Device storing apparatus is placed in the pushing sheath tube, and the closed cell is accommodated in the closer storing apparatus.
Further, the pushing sheath tube front end is through-hole, and the front end of the through hole extends a closer release portion, described
Closer release portion is cylindrical shape, and closer release portion cylindrical shape inner section diameter is identical as the through-hole diameter size；
The pushing sheath tube front end outer side is provided with spacing block set；
The guide portion of smooth surface is equipped with outside closer release portion.
Further, the through-hole is equipped with closer storing apparatus slideway in contrast to the side in closer release portion, is used for
Closer storing apparatus is guided to through hole.
Further, there is an accommodation space, the accommodation space is cylindrical shape, described in the closer storing apparatus
The interior diameter of accommodation space is less than the diameter of through-hole, and the overall diameter of storing apparatus is greater than the diameter of through-hole.
Further, the first closer and the second closer are placed in two sides opposite in closer accommodation space.
Method of closing at a kind of acleistocardia or Small Atrial Septal Defect, using above-mentioned acleistocardia or cubicle
Every the conveying device of defect closing device, the method are as follows:
A) application guidance seal wire, through upper limb/veins of lower extremity, until atrium dextrum, reaches at oval foramen or atrial septal defect, and convex
It extends through at oval foramen or atrial septal defect；
B) pushing sheath tube of closing device is delivered at oval foramen or atrial septal defect along guidance seal wire, portion to be guided
Into after defect, extraction guidance seal wire pushes delivery guidewire, extension and embedded division is made to enter left room side；
C) further push delivery guidewire, the extension be unfolded, the embedded division contradict in acleistocardia or
Side at atrial septal defect；
D) in 6-10 minutes, radiography observes the conflict position of embedded division, and adjustment contradicts position and pulls delivery guidewire, makes
Embedded division is embedded in defect side, and after 10-15 minutes, memory metal completes curling, the embedded division curling insertion oval foramen
Closure is completed in side at patent or atrial septal defect, discharges closing device.
Beneficial effects of the present invention: according to the technical solution of the present invention, it can be achieved that the acleistocardia or room for being less than 5mm
Septal defect carries out minimally invasive closure, and embedded device is small, easily positions, and can discharge recycling repeatedly, and then realization ensures in accurate position
Setting closer is set, and resistance flowing effect is strong.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the embodiment of the present invention；
Fig. 2 is the closing device installation procedure figure that the embodiment of the present invention proposes.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right
The present invention is explained in further detail.It should be appreciated that described herein, the specific embodiments are only for explaining the present invention, not
For limiting the present invention.
On the contrary, the present invention covers any substitution done on the essence and scope of the present invention being defined by the claims, repairs
Change, equivalent method and scheme.Further, in order to make the public have a better understanding the present invention, below to of the invention thin
It is detailed to describe some specific detail sections in section description.
As shown in Figure 1, being the structural schematic diagram of one embodiment of the invention, which shows a kind of oval
The overall structure of hole patent or atrial septal defect closing device, the acleistocardia or Small Atrial Septal Defect closing device are set
It sets in defect point.
The acleistocardia or atrial septal defect closure include the first closer 1 and the second closer 2, and described first closes
Clutch 1 and second closer 2 will hook at atrial septal defect jointly to be closed, 2 structure of first closer 1 and the second closer
It is identical.
First closer 1 include the first extension 11 and the first embedded division 12, first extension 11 with it is described
The connection of first embedded division 12, second closer 2 include the second extension 21 and the second embedded division 22, second extension
21 connect with second embedded division 22, and first extension 11 is connect with the second extension 21 by central connection point 3,
And the described central connection point 3 connects delivery guidewire 6, by delivery guidewire 6, it can be achieved that the same of the first, second closer 1,2
When control.
First extension 11 and the second extension 21 are connected in delivery guidewire 6 by screw joining manner.
First embedded division 12 and the second embedded division 22 be extend on the inside of central connection point 3 it is curly,
In the state that one closer 1 and the second closer 2 are thoroughly opened, first embedded division 12 and the second embedded division 22 are embedded in institute
Side at acleistocardia or atrial septal defect is stated, specially the first embedded division 12 is with place embedded by the second embedded division 22
At acleistocardia or atrial septal defect at position opposite on side, and combine the first extension 11 and the second extension 21 will
Conjunction is completely hooked at atrial septal defect.
Wherein first extension 11 and the second extension 21 are elastic metallic material, concretely in the prior art,
With elastic metal material, such as beryllium-bronze, spring steel etc.；First embedded division 12 and the second embedded division 22
For memory metal material, concretely Ni-Ti alloys such as ambrose alloy, titanium ferronickel, titanium nickel chromium triangle by the emperor himself.
The present invention also provides one for acleistocardia or the conveying device of atrial septal defect closing device, the conveying dress
It sets including pushing sheath tube 4 and a closer storing apparatus 5, the closer storing apparatus 5 is placed in the pushing sheath tube 4, institute
Stating 4 front end of pushing sheath tube is through-hole 41, and a closer release portion 42 is extended in the 41 front end side of through-hole, and the closer is released
Portion 42 is put as cylindrical shape, and the cylindrical inner is smooth, cylindric inner section diameter is identical as 41 diameter of through-hole,
42 side of closer release portion is provided with the guide portion 45 of smooth surface, the guide portion 45 generally smooth surface,
After reaching at acleistocardia or atrial septal defect, by the guidance of smooth surface so that closer release portion 42 is placed in oval foramen
Centre at patent or atrial septal defect, the through-hole 41 are accommodated in contrast to the side in closer release portion 42 equipped with closer
Device slideway 43, for guiding closer storing apparatus 5 to through-hole 41；Setting limit is also possible on the outside of the pushing sheath tube 4
Device 44 processed, the limits device 44 are convex block, for being stuck in outside at atrial septal defect, closer release portion 42 are avoided to protrude out
Excessively.
There is an accommodation space in the closer storing apparatus 5, first closer 1 and the second closer 2 are set
In in the accommodation space, and the accommodation space is cylindrical shape, and the interior diameter of the accommodation space is slightly less than the diameter of through-hole 41,
The overall diameter of storing apparatus 5 is slightly larger than the diameter of through-hole 51.
When the first closer 1 and the second closer 2 are to draw close state, the first closer 1 and the second closer 2 are placed in
Opposite two sides.
As shown in Fig. 2, being closed the present invention also provides a kind of above-mentioned conveying device of application to acleistocardia or atrial septal defect
The operating method for the placement set is attached together, the operating method of the placement specifically comprises the following steps:
A) application guidance seal wire, through upper limb/veins of lower extremity, until atrium dextrum, reaches at oval foramen or atrial septal defect, and convex
It extends through at oval foramen or atrial septal defect；
B) pushing sheath tube of closing device is delivered at oval foramen or atrial septal defect along guidance seal wire, portion to be guided
Into after defect, extraction guidance seal wire pushes delivery guidewire, extension and embedded division is made to enter left room side；
C) further push delivery guidewire, the extension be unfolded, the embedded division contradict in acleistocardia or
Side at atrial septal defect；
D) in 6-10 minutes, radiography observes the conflict position of embedded division, and adjustment contradicts position and pulls delivery guidewire, makes
Embedded division is embedded in defect side, and after 10-15 minutes, memory metal completes curling, the embedded division curling insertion oval foramen
Closure is completed in side at patent or atrial septal defect, discharges closing device；Realize that hooking conjunction acleistocardia or atrial septum completely lacks
Damage is completed to place, if place inaccuracy, by drawing seal wire within the effective time before memory metal deformation, is led
Draw, under the position restriction effect of storing apparatus front end, the first closer and the second closer is recovered to closer and accommodate dress
In setting, position is adjusted again, discharges closer, until accurate installation.
Claims (6)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610035276.2A CN105520758B (en) | 2016-01-19 | 2016-01-19 | A closure device for patent foramen ovale or small atrial septal defect |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610035276.2A CN105520758B (en) | 2016-01-19 | 2016-01-19 | A closure device for patent foramen ovale or small atrial septal defect |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105520758A CN105520758A (en) | 2016-04-27 |
| CN105520758B true CN105520758B (en) | 2019-01-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610035276.2A Active CN105520758B (en) | 2016-01-19 | 2016-01-19 | A closure device for patent foramen ovale or small atrial septal defect |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113827285B (en) * | 2021-09-15 | 2025-06-24 | 宁波迪创医疗科技有限公司 | Closure devices for tissue defects |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7338514B2 (en) * | 2001-06-01 | 2008-03-04 | St. Jude Medical, Cardiology Division, Inc. | Closure devices, related delivery methods and tools, and related methods of use |
| US20050192627A1 (en) * | 2003-10-10 | 2005-09-01 | Whisenant Brian K. | Patent foramen ovale closure devices, delivery apparatus and related methods and systems |
| US20070198057A1 (en) * | 2006-02-21 | 2007-08-23 | Daniel Gelbart | Method and device for closing holes in tissue |
| US20080039743A1 (en) * | 2006-08-09 | 2008-02-14 | Coherex Medical, Inc. | Methods for determining characteristics of an internal tissue opening |
| CN101234042B (en) * | 2008-01-31 | 2010-08-11 | 上海交通大学 | Method for knitting degradable heart atrial septal defect plugging device |
| US8821532B2 (en) * | 2009-01-30 | 2014-09-02 | Cook Medical Technologies Llc | Vascular closure device |
| CA2801923A1 (en) * | 2010-06-11 | 2011-12-15 | Entourage Medical Technologies, Inc. | System and method for transapical access and closure |
| HK1220339A1 (en) * | 2013-03-14 | 2017-05-05 | Jc Medical, Inc. | Tissue and vascular closure devices and methods of use thereof |
| CN205458820U (en) * | 2016-01-19 | 2016-08-17 | 高伟 | Acleistocardia or little atrial septal defect's closing device and conveyor thereof |
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Effective date of registration: 20231017 Address after: 100037 Beijing City, Xicheng District No. 167 North Patentee after: FUWAI HOSPITAL, CHINESE ACADEMY OF MEDICAL SCIENCES Address before: No. 167 Beilishi Road, Xicheng District, Beijing, 100035 Patentee before: Gao Wei |