CN105477015A - External-use traditional Chinese medicine lotion for postoperative anal fistula and preparation method thereof - Google Patents
External-use traditional Chinese medicine lotion for postoperative anal fistula and preparation method thereof Download PDFInfo
- Publication number
- CN105477015A CN105477015A CN201610017323.0A CN201610017323A CN105477015A CN 105477015 A CN105477015 A CN 105477015A CN 201610017323 A CN201610017323 A CN 201610017323A CN 105477015 A CN105477015 A CN 105477015A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- anal fistula
- preparation
- medicine lotion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 38
- 208000004680 Rectal Fistula Diseases 0.000 title claims abstract description 30
- 206010002156 anal fistula Diseases 0.000 title claims abstract description 30
- 239000006210 lotion Substances 0.000 title claims abstract description 16
- 238000002360 preparation method Methods 0.000 title claims description 19
- 230000002980 postoperative effect Effects 0.000 title abstract description 5
- 229910021538 borax Inorganic materials 0.000 claims abstract description 17
- 239000004328 sodium tetraborate Substances 0.000 claims abstract description 17
- 235000010339 sodium tetraborate Nutrition 0.000 claims abstract description 17
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 16
- RSIJVJUOQBWMIM-UHFFFAOYSA-L sodium sulfate decahydrate Chemical compound O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=O RSIJVJUOQBWMIM-UHFFFAOYSA-L 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 17
- 230000008569 process Effects 0.000 claims description 15
- 239000002994 raw material Substances 0.000 claims description 12
- 239000000843 powder Substances 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 3
- 238000010298 pulverizing process Methods 0.000 claims description 2
- 230000035876 healing Effects 0.000 abstract description 10
- 208000024891 symptom Diseases 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 9
- 206010030113 Oedema Diseases 0.000 abstract description 8
- 230000001737 promoting effect Effects 0.000 abstract description 5
- 208000003251 Pruritus Diseases 0.000 abstract description 4
- 230000008961 swelling Effects 0.000 abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 4
- 238000005469 granulation Methods 0.000 abstract description 3
- 230000003179 granulation Effects 0.000 abstract description 3
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 abstract description 2
- 238000005406 washing Methods 0.000 abstract description 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- 229940105847 calamine Drugs 0.000 abstract 1
- 230000003467 diminishing effect Effects 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 229910052864 hemimorphite Inorganic materials 0.000 abstract 1
- 239000010446 mirabilite Substances 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
- 235000014692 zinc oxide Nutrition 0.000 abstract 1
- 239000011787 zinc oxide Substances 0.000 abstract 1
- CPYIZQLXMGRKSW-UHFFFAOYSA-N zinc;iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[Fe+3].[Fe+3].[Zn+2] CPYIZQLXMGRKSW-UHFFFAOYSA-N 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 description 7
- 208000027418 Wounds and injury Diseases 0.000 description 7
- 201000010099 disease Diseases 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 206010053692 Wound complication Diseases 0.000 description 6
- 201000004624 Dermatitis Diseases 0.000 description 4
- 230000003110 anti-inflammatory effect Effects 0.000 description 4
- 208000010668 atopic eczema Diseases 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 239000012286 potassium permanganate Substances 0.000 description 4
- 230000001139 anti-pruritic effect Effects 0.000 description 3
- 239000003908 antipruritic agent Substances 0.000 description 3
- 230000008030 elimination Effects 0.000 description 3
- 238000003379 elimination reaction Methods 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 239000003440 toxic substance Substances 0.000 description 3
- 206010007247 Carbuncle Diseases 0.000 description 2
- 206010016717 Fistula Diseases 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- 208000033809 Suppuration Diseases 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 238000004090 dissolution Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000003890 fistula Effects 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000000242 pagocytic effect Effects 0.000 description 2
- 230000000391 smoking effect Effects 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 206010048946 Anal abscess Diseases 0.000 description 1
- 206010002153 Anal fissure Diseases 0.000 description 1
- 208000016583 Anus disease Diseases 0.000 description 1
- 241000193738 Bacillus anthracis Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 208000011231 Crohn disease Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 208000009531 Fissure in Ano Diseases 0.000 description 1
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000475481 Nebula Species 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000191963 Staphylococcus epidermidis Species 0.000 description 1
- 241000193996 Streptococcus pyogenes Species 0.000 description 1
- 210000002255 anal canal Anatomy 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000009414 anorectal function Effects 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 239000003907 antipyretic analgesic agent Substances 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 208000010217 blepharitis Diseases 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- 230000009172 bursting Effects 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 210000000589 cicatrix Anatomy 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000010339 dilation Effects 0.000 description 1
- 201000001747 discharging ear Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000013210 hematogenous Diseases 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000008338 local blood flow Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 210000001616 monocyte Anatomy 0.000 description 1
- 210000000865 mononuclear phagocyte system Anatomy 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000004224 protection Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/22—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides an external-use traditional Chinese medicine lotion for the postoperative anal fistula. The traditional Chinese medicine lotion is prepared from, by weight, 25-35 parts of mirabilite, 15-25 parts of borax, 5-15 parts of alumen, 25-35 parts of roasted calamine and 5-15 parts of borneol. The prepared lotion is dissolved in water for fuming and washing and a hip bath, and has the effects of eliminating or relieving wound surface pain, edema, seepage, healing delaying and other symptoms of the postoperative anal fistula, resolving toxin with clearing coolness, relieving itch and diminishing swelling and achieving astringing and promoting granulation.
Description
Technical field
The present invention relates to technical field of Chinese medicine, being specifically related to a kind of for eliminating or the Chinese medicine preparation alleviating the symptoms such as anal fistula after operation wound pain, edema, sepage, healing delay and preparation method thereof.
Background technology
Chinese medicine anal fistula refers to that anal abscess becomes pus from bursting or cutting the rear tube chamber left over.Have inside and outside two mouthfuls, collar extension often has pus or excrement juice to flow out, and has streak thing under it, and internal orifice is positioned at the sick class disease of fistula that anus tooth trace portion is main manifestations; Anal fistula is common clinical, surgical operation is the method for unique healing at present, but due to the particularity of diseased region, general wound surface is comparatively large and structure is more complicated, the process of postoperative wound surface reparative regeneration is longer, and wound is easily infected, common wound pain, edema, sepage, delayed union etc., operation and complication often affect anorectal function, bring larger misery to patient.The generation of primary disease, bursts for carbuncle around anal orifice and rectal intestine and does not close up for a long time afterwards, and damp and hot residual poison end is most, hematogenous blockage; Or because of the dirty loss of spleen lung kidney three, or damage because of anal fissure and infect, cause fistulization; The primary symptom of anal fistula for suppurating, pain, pruritus, heating in various degree can be had time serious or with becoming thin, anemia, body be empty etc., and long-term chronic consumes symptom.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine for outer use for anal fistula after operation having elimination or alleviate the symptoms such as anal fistula after operation wound pain, edema, sepage, healing delay.
Another object of the present invention is to the preparation method that a kind of above-mentioned Chinese medicine preparation is provided.
In order to solve the problems of the technologies described above, the technical solution used in the present invention is: a kind of external application Chinese medicine lotion for anal fistula after operation, described Chinese medicine preparation is prepared from by the powder raw material of following weight portion: 25 ~ 35 parts, Natrii Sulfas, Borax 15 ~ 25 parts, Alumen 5 ~ 15 parts, process Calamina 25 ~ 35 parts, Borneolum Syntheticum 5 ~ 15 parts.
Preferably, described Chinese medicine preparation is prepared from by the powder raw material of following weight portion: 25 ~ 30 parts, Natrii Sulfas, Borax 15 ~ 20 parts, and Alumen 5 ~ 10 parts processs Calamina 25 ~ 30 parts, Borneolum Syntheticum 5 ~ 10 parts.
Optimum proportioning is: in described Chinese medicine lotion, the weight portion of each component is 30 parts, Natrii Sulfas, Borax 20 parts, and Alumen 10 parts processs Calamina 30 parts, Borneolum Syntheticum 10 parts.
A preparation method for above-mentioned Chinese medicine preparation, specifically comprises the following steps:
A. each component in described Chinese medicine is ground respectively,
B. the raw material mix homogeneously of each weight portion of pulverizing is taken by proportioning.
The purposes of above-mentioned Chinese medicine preparation: medicament dissolution is washed demibain in water smoking, first smokes and washes afterwards, 2 times/day, each 15-20min, temperature 40-45 DEG C.
In Chinese medicine preparation of the present invention, each component pharmacology is as follows:
Natrii Sulfas: salty in the mouth is bitter, cold in nature, enters stomach, large intestine channel, under rushing down, softening the hard mass, heat clearing away., constipation due to dry stool, sore, carbuncle and painful swelling stagnant for excess-heat.In addition, the main contains sodium sulfate of Natrii Sulfas, still assorted have Sal, calcium sulfate, magnesium sulfate etc.Modern study thinks that Natrii Sulfas has obvious stimulation to reticuloendothelial system, its hypertrophy phenomenon and phagocytic activity being strengthened to some extent, strengthens the antiinflammatory action of body, by stimulating the neural reflex of body, regional flow's blood supply being enriched, accelerate lymphocyte to generate, have anti-inflammatory analgetic effect.Can make local vascular dilation after Natrii Sulfas external, blood flow is accelerated, and improves microcirculation, thus transfer the resistance against diseases of body, make phagocytic activity of monocyte strengthen simultaneously, accelerate absorption and the dissipation of inflammation, and it has height and oozes effect, also accelerate dissipation and the absorption of swollen tissue.
Borax: nature and flavor are sweet, salty, cool in nature.Tool heat clearing away expectorant, anticorrosion effect of detoxifying.Modern medicine surface, Borax is a weak base, and it is the same with boric acid weak bacteriostasis. all have inhibitory action to escherichia coli, bacillus pyocyaneus, anthrax bacillus, staphylococcus, Candida albicans etc., the sterilization that can be used for skin mucosa is anticorrosion.
Alumen: sour, puckery, cold, enters lung, spleen, liver, large intestine channel.External removing toxic substances parasite killing, dampness removing to stop itchin; Hemostasis antidiarrheal for oral administration, dispels wind-phlegm.Dried Alumen removing dampness sore, hemostasisization is rotten.For eczema eczema, Ting discharging ear, pudendal pruritus leukorrhagia.In addition, Alumen water can make serum precipitate immediately in vitro, has the effect of strong coagulated protein, and it is hemorrhage to treat anal fistula after operation.
Process Calamina: sweet in the mouth, property are flat, enter liver, stomach warp, removing toxic substances improving acuity of vision and removing nebula, removing dampness promoting tissue regeneration and ulcer healing.For cataract, marginal blepharitis eye, ulcer being unable to heal, skin eczema.Pharmacological research shows that it has good inhibitory action to staphylococcus aureus, staphylococcus epidermidis and Streptococcus hemolyticus, can absorb the secretions of wound surface simultaneously, has anticorrosion, antiinflammatory, antipruritic and protection wound surface effect.
Borneolum Syntheticum: acrid in the mouth is bitter, cold nature, enters the heart, spleen, lung meridian, refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.Can antipyretic analgesic, promote granulation tissue growth, there is the effect of bacteria growing inhibiting simultaneously.
Beneficial effect of the present invention: the normal indolence of anal fistula otch, easy recurrence, Natrii Sulfas, Alumen mass dissipating and swelling eliminating in Chinese medicine preparation provided by the invention (five disappear in vain fistula fall apart), to restrain antipruritic be monarch drug altogether, Borax refreshing and detoxicating, antiinflammatory sore are minister, assistant is with the antipruritic sore of Calamina removing dampness, with Borneolum Syntheticum heat-clearing and toxic substances removing, convergence granulation promoting.Thus medicament prepared by the present invention is conducive to promoting wound healing, prevents recurrence, prevention local scar is formed, and improves local blood circulation.Fang Zhong, with Natrii Sulfas, Borax, Alumen, process Calamina, Borneolum Syntheticum medicine carries out rational proportion, the hemorrhoid complicated by anal fistula lotion made, for the clinical symptoms of anal fistula after operation, there is effect of refreshing and detoxicating, relieving itching and eliminating swelling, convergence granulation promoting, can eliminate or alleviate the symptoms such as anal fistula after operation wound pain, edema, sepage, healing delay.
Clinical experiment
1, patient data
Choose anal fistula seton art postoperative patient 150 example of being in hospital in my section year January in January, 2013 to 2015; All cases all meet the diagnostic criteria of anal fistula in " the anal fistula clinical diagnosis and treatment guide " of Society of Surgery of China's anorectal surgical group formulation in 2004, are divided into treatment group and matched group according to random digits table, matched group 72 example, treatment group 78 example.In matched group 72 example, man 38 example, female 34 example; 21 ~ 68 years old age, average (31 ± 2) year; The course of disease 1 month to 6 years, average (2 ± 1) year.In treatment group 78 example, man 43 example, female 35 example; 16 ~ 58 years old age, average (30 ± 2) year; The course of disease 2 months to 5.5 years, average (2 ± 0.5) year.The physical data such as two groups of Genders, age, courses of disease compare, and no significant difference (P > 0.05), has comparability.
2, case inclusive criteria
Case inclusive criteria: (1) meets the diagnostic criteria of anal fistula; (2) age was at 16 ~ 68 years old; (3) all patients did not adopt fumigation-washing medicine to treat in 1 week; (4) without following situations: 1. with tuberculosis infection anal fistula, Crohn disease, carcinous anal fistula, anal eczema person; 2. anal canal, the rectum person that has occupying lesion; 3. patient is associated with other system major disease person; 4. trimester of pregnancy or age of sucking patient; (5) row operative treatment person is first; (6) voluntary participation clinical observation.
3, treatment and observational technique
Treatment group: select medicament dissolution of the present invention to wash demibain in water smoking, first smoke and wash afterwards, 2 times/day, each 15-20min, temperature 40-45 DEG C;
Matched group: use 1:5000 potassium permanganate solution, first smokes and washes afterwards, 2 times/day, each 15-20min, temperature 40-45 DEG C.
4, efficacy result
It is fixed that criterion of therapeutical effect is drawn up certainly with reference to " traditional Chinese medical science anorectum department disease Standardization of diagnosis and curative effect ", and take healing time as evaluation criterion, namely wound surface epithelium covers completely, cicatrix is solid, without false healing, observes wound surface do not fester again through 1 week, local edema pain symptom disappears, without hemorrhage for curing.
Two groups for the treatment of times compare, and the results are shown in Table 1
As shown in table 1,2 groups of patients all cure, and adopting Chinese medicine of the present invention relative to potassium permanganate, treatment time obviously shortens, thus proves that it is more better than potassium permanganate in the symptoms such as elimination or alleviation anal fistula after operation wound pain, edema, sepage, healing delay.
Analyze through Ridit, adopt Chinese medicine of the present invention elimination or alleviate in the symptoms such as anal fistula after operation wound pain, edema, sepage, healing delay with potassium permanganate matched group ratio, curative effect is significantly good.
Detailed description of the invention
Embodiment 1
1. the preparation method for the external application Chinese medicine lotion of anal fistula after operation: specifically comprise the following steps:
A. by raw material Natrii Sulfas, Borax, Alumen, process Calamina, Borneolum Syntheticum is pulverized respectively;
B. the powder raw material taking following weight portion is mixed with and forms: 25 parts, Natrii Sulfas, Borax 15 parts, and Alumen 5 parts processs Calamina 25 parts, Borneolum Syntheticum 5 parts.
Embodiment 2
1. the preparation method for the external application Chinese medicine lotion of anal fistula after operation: specifically comprise the following steps:
A. by raw material Natrii Sulfas, Borax, Alumen, process Calamina, Borneolum Syntheticum is pulverized respectively;
B. the powder raw material taking following weight portion is mixed with and forms: 35 parts, Natrii Sulfas, Borax 25 parts, and Alumen 15 parts processs Calamina 35 parts, Borneolum Syntheticum 15 parts.
Embodiment 3
1. the preparation method for the external application Chinese medicine lotion of anal fistula after operation: specifically comprise the following steps:
A. by raw material Natrii Sulfas, Borax, Alumen, process Calamina, Borneolum Syntheticum is pulverized respectively;
B. the powder raw material taking following weight portion is mixed with and forms: 30 parts, Natrii Sulfas, Borax 20 parts, and Alumen 10 parts processs Calamina 30 parts, Borneolum Syntheticum 10 parts.
Claims (4)
1. for an external application Chinese medicine lotion for anal fistula after operation, it is characterized in that: described Chinese medicine preparation is prepared from by the powder raw material of following weight portion: 25 ~ 35 parts, Natrii Sulfas, Borax 15 ~ 25 parts, Alumen 5 ~ 15 parts, process Calamina 25 ~ 35 parts, Borneolum Syntheticum 5 ~ 15 parts.
2. a kind of external application Chinese medicine lotion for anal fistula after operation as claimed in claim 1, it is characterized in that: described Chinese medicine preparation is prepared from by the powder raw material of following weight portion: 25 ~ 30 parts, Natrii Sulfas, Borax 15 ~ 20 parts, Alumen 5 ~ 10 parts, process Calamina 25 ~ 30 parts, Borneolum Syntheticum 5 ~ 10 parts.
3. a kind of external application Chinese medicine lotion for anal fistula after operation as claimed in claim 1, it is characterized in that: in described Chinese medicine lotion, the weight portion of each component is 30 parts, Natrii Sulfas, Borax 20 parts, Alumen 10 parts processs Calamina 30 parts, Borneolum Syntheticum 10 parts.
4. a preparation method for Chinese medicine lotion as claimed in claim 1, is characterized in that: specifically comprise the following steps:
Each component in described Chinese medicine is ground respectively,
The raw material mix homogeneously of each weight portion of pulverizing is taken by proportioning.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610017323.0A CN105477015A (en) | 2016-01-12 | 2016-01-12 | External-use traditional Chinese medicine lotion for postoperative anal fistula and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610017323.0A CN105477015A (en) | 2016-01-12 | 2016-01-12 | External-use traditional Chinese medicine lotion for postoperative anal fistula and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105477015A true CN105477015A (en) | 2016-04-13 |
Family
ID=55664530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610017323.0A Pending CN105477015A (en) | 2016-01-12 | 2016-01-12 | External-use traditional Chinese medicine lotion for postoperative anal fistula and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105477015A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108653356A (en) * | 2018-05-30 | 2018-10-16 | 安徽德睿轩科技服务有限公司 | A kind of pharmaceutical composition and its application for treating anorectal disease |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1089498A (en) * | 1993-01-11 | 1994-07-20 | 绵竹县中医医院 | Fumigant for curing anal and intestinal disease |
| CN1493350A (en) * | 2003-09-18 | 2004-05-05 | 江苏扬子江药业集团有限公司 | Chinese medicine compound preparation for treating piles and preparing process thereof |
-
2016
- 2016-01-12 CN CN201610017323.0A patent/CN105477015A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1089498A (en) * | 1993-01-11 | 1994-07-20 | 绵竹县中医医院 | Fumigant for curing anal and intestinal disease |
| CN1493350A (en) * | 2003-09-18 | 2004-05-05 | 江苏扬子江药业集团有限公司 | Chinese medicine compound preparation for treating piles and preparing process thereof |
Non-Patent Citations (2)
| Title |
|---|
| 崔世超、王荣: "一效膏配合痔疮散促进肛周脓肿术后创面愈合32例", 《中医外治杂志》 * |
| 颜永惠: "中药熏洗治疗肛瘘术后54例疗效观察", 《航空航天医药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108653356A (en) * | 2018-05-30 | 2018-10-16 | 安徽德睿轩科技服务有限公司 | A kind of pharmaceutical composition and its application for treating anorectal disease |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103263534B (en) | Traditional Chinese medicine composition for treating haemorrhoids and preparation method thereof | |
| CN108619362A (en) | A kind of acne cream and preparation method thereof | |
| CN103599229B (en) | A kind of anus washing liquid and preparation method thereof | |
| CN107184703A (en) | A kind of three sub- anti-itching lotions and its preparation technology and application | |
| CN103272019B (en) | Traditional Chinese medicinal composition for treating wind-heat and intestine-dryness type haememorrhoids | |
| CN105477015A (en) | External-use traditional Chinese medicine lotion for postoperative anal fistula and preparation method thereof | |
| CN105288071A (en) | Traditional Chinese medicine formula used for treatment of hemorrhoid and postoperative nursing and preparation method | |
| CN115381875A (en) | Traditional Chinese medicine composition for external hemorrhoid and mixed hemorrhoid postoperation, lotion and application | |
| CN113209179A (en) | External washing medicine for hemorrhoids and fistula and preparation method and application method thereof | |
| CN102772485A (en) | External multi-functional ointment for clearing away heat and toxic materials | |
| CN1217683C (en) | Prescription of lotion for treating pile and fistula and its preapring process | |
| WO2022011881A1 (en) | Medication for preventing and treating hemorrhoids and use thereof | |
| CN100355437C (en) | Medicine for treating scald and burn and preparing method | |
| CN101406583A (en) | Externally applied Chinese medicine ointment for treating pyogenic skin infection caused by skin traumatism | |
| CN108114090A (en) | A kind of Chinese medicine composition for treating hemorrhoid and burn and scald | |
| CN104547757A (en) | Traditional Chinese medicine for treating amygdalitis and adenoidal hypertrophy | |
| CN115429869B (en) | Traditional Chinese medicine composition for treating cold-dampness obstruction type lumbago and preparation method thereof | |
| CN103720749A (en) | Traditional Chinese medicinal preparation for treating elytritis | |
| CN108771702A (en) | A kind of external fumigation and washing bacteriostatic agent for human body anal skin | |
| CN107854542A (en) | A kind of Chinese medicine preparation for treating inside and outside hemorrhoid and preparation method thereof | |
| CN108186864A (en) | A kind of Chinese medicine for treating acne | |
| CN107080762B (en) | Application of sweet potato as medicine for treating hemorrhoids | |
| Lamina et al. | Shortwave diathermy in the management of chronic pelvic inflammatory disease pain | |
| CN104189154B (en) | A kind of Chinese medicine preparation for the treatment of viral conjunctivitis | |
| Liu et al. | The Efficacy of Sophora Flavescens Fumigation in Improving Anal Health After Anal Fistula Surgery. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160413 |
|
| RJ01 | Rejection of invention patent application after publication |