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CN105456887A - Pharmaceutical for treating aplastic anemia - Google Patents

Pharmaceutical for treating aplastic anemia Download PDF

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Publication number
CN105456887A
CN105456887A CN201510932438.8A CN201510932438A CN105456887A CN 105456887 A CN105456887 A CN 105456887A CN 201510932438 A CN201510932438 A CN 201510932438A CN 105456887 A CN105456887 A CN 105456887A
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parts
radix
fructus
herba
rhizoma
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不公告发明人
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    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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Abstract

The invention discloses a pharmaceutical for treating aplastic anemia, made from traditional Chinese medicinal materials in the following parts by weight: 30-40 parts of Radix Rehmanniae, 30-40 parts of Radix Rehmanniae Preparata, 10-20 parts of Radix Ophiopogonis, 10-20 parts of Fructus Lycii, 10-20 parts of Semen Cuscutae, 10-15 parts of Herba Ecliptae, 5-10 parts of Fructus Mori, 15-20 parts of Colla Corii Asini, 10-20 parts of Radix Polygoni Multiflori, 20-30 parts of Rhizoma Dioscoreae, 10-20 parts of Radix Astragali, 10-20 parts of Radix Ginseng, 6-10 parts of Fructus Psoraleae, 6-10 parts of Radix Angelicae Sinensis, 15-20 parts of Poria, 10-20 parts of Radix Glycyrrhizae, 10-20 parts of Fructus Ligustri Lucidi, 15-25 parts of Cortex Moutan, 10-20 parts of Rhizoma Atractylodis Macrocephalae, 20-30 parts of Semen Sesami Nigri, 10-20 parts of Radix Scrophularia, 15-25 parts of Rhizoma Polygoni Cuspidati, 10-20 parts of Radix Asparagi, 15-20 parts of Herba Agrimoniae, 10-20 parts of Rhizoma Curculiginis, 10-20 parts of Colla Carapacis et Plastri Testudinis, 10-20 parts of Colla Cornus Cervi, 10-20 parts of Herba Epimedii, 10-20 parts of Placenta Hominis, 10-15 parts of Caulis Spatholobi, 10-15 parts of Radix Notoginseng, 10-15 parts of Fructus Amomi, and 10-15 parts of Herba Cynomorii. The herbs are matched by differentiation, and the pharmaceutical is effective in nourishing and suppressing Yang, tonifying kidney to secure essence, softening hardness to dissipate stagnation, abating fever to eliminate steam, cooling blood and expelling blood-stasis, astringing to stop bleeding, harmonizing nutrition to nourish blood and the like, and are highly efficient in treating aplastic anemia without toxic or side effect.

Description

A kind of medicine being used for the treatment of aplastic anemia
Technical field
The present invention relates to a kind of medicine for the treatment of aplastic anemia.
Background technology
Aplastic anemia, aplastic anemia is often referred to primary bone marrow hemopoietic function exhaustion syndrome, etiology unknown, and main manifestations is hemopoietic hypofunction of marrow, pancytopenia and anemia, hemorrhage, infect.According to the state of an illness of patient, bone marrow smear and prognosis, heavy and non-heavy type can be divided into.Heavy onset is anxious, and state of an illness weight, minority can be in progress by non-Severe aplastic anemia.Non-Severe aplastic anemia onset and progress comparatively slow, anemia, infection and hemorrhage degree are gently heavier, control nonresponder for a long time and intracranial hemorrhage and threat to life can occur.Clinical manifestation is mainly anemia: pale, weak, dizzy, cardiopalmus and the symptom Progressive symmetric erythrokeratodermia such as to breathe hard increase the weight of, most of patients has heating, the most common with respiratory tract infection, secondly digestive tract, urogenital tract and skin mucosa etc., skin can have petechia or large stretch of ecchymosis, and oral mucosa has bleeding blister, epistaxis, gingival hemorrhage, conjunctiva palpebrae is hemorrhage.
Mainly immunosuppressant and the hormone therapy etc. of current clinical treatment, not only price, side effect is many, and relapse rate is high, and light-duty case and young woman's case are also not suitable for the treatment of androgen.
Summary of the invention
The object of the present invention is to provide a kind of medicine being used for the treatment of aplastic anemia, this medicine has the advantages such as cost is low, curative effect is good.
Technical scheme of the present invention comprises:
A kind of medicine being used for the treatment of aplastic anemia, it is made by the raw material of Chinese medicine of following weight: Radix Rehmanniae 30-40 part, Radix Rehmanniae Preparata 30-40 part, Radix Ophiopogonis 10-20 part, Fructus Lycii 10-20 part, Semen Cuscutae 10-20 part, Herba Ecliptae 10-15 part, Fructus Mori 5-10 part, Colla Corii Asini 15-20 part, Radix Polygoni Multiflori 10-20 part, Rhizoma Dioscoreae 20-30 part, Radix Astragali 10-20 part, Radix Ginseng 10-20 part, Fructus Psoraleae 6-10 part, Radix Angelicae Sinensis 6-10 part, Poria 15-20 part, Radix Glycyrrhizae 10-20 part, Fructus Ligustri Lucidi 10-20 part, Cortex Moutan 15-25 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Semen Sesami Nigrum 20-30 part, Radix Scrophulariae 10-20 part, Rhizoma Polygoni Cuspidati 15-25 part, Radix Asparagi 10-20 part, Herba Agrimoniae 15-20 part, Rhizoma Curculiginis 10-20 part, Colla Plastri Testudinis 10-20 part, Colla cornus cervi 10-20 part, Herba Epimedii 10-20 part, Placenta Hominis 10-20 part, Caulis Spatholobi 10-15 part, Radix Notoginseng 10-15 part, Fructus Amomi 10-15 part, Herba Cynomorii 10-15 part.
Preferably, the weight of above-mentioned each raw material of Chinese medicine is: 35 parts, the Radix Rehmanniae, 35 parts, Radix Rehmanniae Preparata, Radix Ophiopogonis 15 parts, Fructus Lycii 15 parts, Semen Cuscutae 15 parts, Herba Ecliptae 12 parts, 7 parts, Fructus Mori, 17 parts, Colla Corii Asini, the Radix Polygoni Multiflori 15 parts, Rhizoma Dioscoreae 25 parts, the Radix Astragali 15 parts, Radix Ginseng 15 parts, Fructus Psoraleae 8 parts, Radix Angelicae Sinensis 8 parts, 17 parts, Poria, 15 parts, Radix Glycyrrhizae, Fructus Ligustri Lucidi 15 parts, Cortex Moutan 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Semen Sesami Nigrum 25 parts, Radix Scrophulariae 15 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Asparagi 15 parts, Herba Agrimoniae 17 parts, Rhizoma Curculiginis 15 parts, Colla Plastri Testudinis 15 parts, Colla cornus cervi 15 parts, Herba Epimedii 15 parts, Placenta Hominis 15 parts, Caulis Spatholobi 12 parts, 12 parts, Radix Notoginseng, Fructus Amomi 12 parts, Herba Cynomorii 12 parts.
Described medicine specifically adopts following step to make:
A takes raw material of Chinese medicine respectively according to above-mentioned weight proportion, soaks 1 hour after merging, then decocts 2 hours, filters, obtains filtrate one and medicinal residues;
Gained medicinal residues in step a are decocted with water 1 hour by b again, filter, obtain filtrate two and medicinal residues;
Filtrate one and filtrate two merge by c, obtain medicine.
Pharmacology of the present invention and beneficial effect:
Effect that the Radix Rehmanniae has clearing away heat and cooling blood, tonifying YIN promotes the production of body fluid;
Radix Rehmanniae Preparata has the effect of YIN nourishing of enriching blood;
There is YIN nourishing and the production of body fluid promoting Radix Ophiopogonis, effect that lung moistening clears away heart-fire;
Fructus Lycii has the effect reducing blood glucose, anti-fatty liver;
Semen Cuscutae has effect of the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, solid tire stopping leak;
Herba Ecliptae has effect of convergence, hemostasis, invigorating the liver and kidney;
Fructus Mori has effect of good anti-cancer, defying age, antiulcer, antiviral;
Colla Corii Asini has enriching blood, stops blooding, nourshing Yin and drynsessmoistening prescription effect;
The Radix Polygoni Multiflori has effect of blood YIN nourishing, loosening bowel to relieve constipation;
Rhizoma Dioscoreae has spleen reinforcing nourishing the stomach, effect of the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission;
The Radix Astragali has effect of invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation;
Radix Ginseng has physical strength reinforcing, regulates hormone, reduces blood glucose and controls blood pressure, controls effect of liver index;
Fructus Psoraleae has effect of kidney invigorating and YANG supporting, spleen reinforcing stomach invigorating;
Radix Angelicae Sinensis has benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation, anticancer, anti-ageing anti-old, immune effect;
Poria has effect of eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming;
Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain;
Fructus Ligustri Lucidi has effect of liver and kidney tonifying, improving eyesight, clearind deficient heat;
Cortex Moutan has effect of clearing away heat and cooling blood, activating blood circulation to dissipate blood stasis, reducing the asthenic fever;
The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect;
Effect that Semen Sesami Nigrum has invigorating the liver and kidney, benefiting essence-blood, intestine moistening dry;
Radix Scrophulariae has effect of clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing;
Rhizoma Polygoni Cuspidati has effect of heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm;
Radix Asparagi has effect of replenishing YIN and removing heat;
Herba Agrimoniae has effect of hemostasis, heart tonifying, strong, dysentery relieving and antiinflammatory;
Rhizoma Curculiginis has effect of reinforcing the kidney and supporting YANG, benefiting essence-blood, bone and muscle strengthening and promoting the circulation of blood detumescence;
Colla Plastri Testudinis has effect of nourishing YIN for suppressing the hyperactive YANG, replenishing kidney and strengthening bone;
Colla cornus cervi has effect of temperature compensation Liver and kidney, beneficial intensive culture blood;
Herba Epimedii has effect of kidney-replenishing, bone and muscle strengthening, wind-damp dispelling;
Placenta Hominis has the merit of the kidney invigorating and essence nourishing, benefiting QI and nourishing blood;
Caulis Spatholobi has effect of blood circulation promoting and enriching, menstruction regulating and pain relieving, relaxing muscles and tendons and activating QI and blood in the collateral;
Radix Notoginseng has effect of hemostasis, loose blood;
Fructus Amomi has removing dampness appetizing, warming spleen and stopping diarrha, antiabortive effect of regulating the flow of vital energy;
Herba Cynomorii has the kidney invigorating, benefit essence, the effect of moisturizing, and above-mentioned all medicines, through dialectical compatibility, have nourishing YIN for suppressing the hyperactive YANG, supplementing the kidney to control the nocturnal, hard masses softening and resolving, bring down a fever except steaming, cooling blood and dissolving stasis, astringing to arrest bleeding and honor such as to be nourished blood at the effect.
Clinical data
1, case selection: the routine aplastic anemia clients of Stochastic choice 90, man 42 example, female 48 example, minimum 13 years old of age, oldest 45 years old, treatment group 21 man, 24 female, take Chinese medicine decoction of the present invention, matched group 21 man, 24 female, (CSA+ATG) treats;
2, clinical primary symptom: acute and chronic aplastic anemia, green around the gills, weak, dizzy, cardiopalmus, cutaneous manifestations are petechia or large stretch of ecchymosis, occasionally has hemoptysis;
3, Therapeutic Method: oral, a 100ml, twice on the one;
4, points for attention: to quit smoking, wine and pungent, raw and cold, greasy food; Anemia of pregnant woman should take under doctor instructs;
5, curative effect judging standard: (with take within 30 days, be one the course for the treatment of standard)
Cure: symptom all disappears;
Effective: symptom alleviates;
Invalid: symptom is rear unchanged before the treatment.
6, therapeutic effect
Table 1
Patient Number of cases Cure/example Effectively/example Invalid/example Effective percentage
Treatment group 45 18 23 4 91.1%
Matched group 45 8 22 15 66.7%
7, model case
Beam, man, 25 years old, in April, 2013 examined, and patient is gradual fatigue and weak in this year, dizzy lower limb is soft, and full color is pale, occasionally has tooth epistaxis, feverish palms, be afraid of cold, poor appetite, is diagnosed as aplastic anemia, with testosterone propionate and treatment of blood transfusion invalid and to our hospital for half a year.Health check-up: anemia looks, skin is dispersed in petechia, and superficial lymph knot is little, and sclera is without xanthochromia, and 2 grades, apical region of heart systolic murmur, lung (), liver spleen does not touch, lower limb are slight convex sunken property edema, thready pulse CHI-pulse being weak slightly number, pale tongue, white and thin fur.Chemical examination: hemoglobin 30 grams | rise, erythrocyte 14*109| liter, leukocyte 15*109| liter, platelet 20*109| liter, nets red 0.2, sour hemolytic experiment ().Myelosis severe is low, and grain, erythrocyte obviously reduce, and lymphocyte significantly increases, and megalokaryocyte has no, and platelet is few.Diagnosis: chronic aplastic anemia.Chinese medical discrimination: insufficiency of vital energy and blood, liver spleen kidney is all empty.Take Chinese medicine of the present invention after 1 month, hemogram starts to rise, and after half a year, hemogram obviously rises, and stops blood transfusion.In May, 2013, check hemoglobin 139 grams | rise, leukocyte 43*109| liter, platelet 78*109| liter, nets red 2.2, and myelosis is enlivened, and grain, children two are hypertrophy, and lymphocyte is slightly high, and megalokaryocyte is visible, and platelet is less slightly.Continue above-mentioned Chinese medicine after treatment 3 months after leaving hospital, be transitioned into upper full class gradually by first class, during institute's check afterwards in 1 year, hemogram full recovery is normal, recurrence that so far there are no; Efficacy determination: recovery from illness.
Detailed description of the invention
Embodiment 1:
Take 35 parts, the Radix Rehmanniae, 35 parts, Radix Rehmanniae Preparata, Radix Ophiopogonis 15 parts, Fructus Lycii 15 parts, Semen Cuscutae 15 parts, Herba Ecliptae 12 parts, 7 parts, Fructus Mori, 17 parts, Colla Corii Asini, the Radix Polygoni Multiflori 15 parts, Rhizoma Dioscoreae 25 parts, the Radix Astragali 15 parts, Radix Ginseng 15 parts, Fructus Psoraleae 8 parts, Radix Angelicae Sinensis 8 parts, 17 parts, Poria, 15 parts, Radix Glycyrrhizae, Fructus Ligustri Lucidi 15 parts, Cortex Moutan 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Semen Sesami Nigrum 25 parts, Radix Scrophulariae 15 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Asparagi 15 parts, Herba Agrimoniae 17 parts, Rhizoma Curculiginis 15 parts, Colla Plastri Testudinis 15 parts, Colla cornus cervi 15 parts, Herba Epimedii 15 parts, Placenta Hominis 15 parts, Caulis Spatholobi 12 parts, 12 parts, Radix Notoginseng, Fructus Amomi 12 parts, Herba Cynomorii 12 parts.Above-mentioned weight proportion raw material of Chinese medicine soaks 1 hour after merging, and then decocts 2 hours, filters, obtains filtrate one and medicinal residues; Gained medicinal residues are decocted with water 1 hour again, filters, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, obtains medicine.
Embodiment 2:
Take 30 parts, the Radix Rehmanniae, 30 parts, Radix Rehmanniae Preparata, Radix Ophiopogonis 15 parts, Fructus Lycii 15 parts, Semen Cuscutae 15 parts, Herba Ecliptae 12 parts, 7 parts, Fructus Mori, 17 parts, Colla Corii Asini, the Radix Polygoni Multiflori 15 parts, Rhizoma Dioscoreae 25 parts, the Radix Astragali 15 parts, Radix Ginseng 15 parts, Fructus Psoraleae 8 parts, Radix Angelicae Sinensis 8 parts, 17 parts, Poria, 15 parts, Radix Glycyrrhizae, Fructus Ligustri Lucidi 15 parts, Cortex Moutan 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Semen Sesami Nigrum 25 parts, Radix Scrophulariae 15 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Asparagi 15 parts, Herba Agrimoniae 15 parts, Rhizoma Curculiginis 15 parts, Colla Plastri Testudinis 15 parts, Colla cornus cervi 15 parts, Herba Epimedii 15 parts, Placenta Hominis 15 parts, Caulis Spatholobi 15 parts, 12 parts, Radix Notoginseng, Fructus Amomi 15 parts, Herba Cynomorii 15 parts.Above-mentioned weight proportion raw material of Chinese medicine soaks 1 hour after merging, and then decocts 2 hours, filters, obtains filtrate one and medicinal residues; Gained medicinal residues are decocted with water 1 hour again, filters, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, obtains medicine.
Embodiment 3:
Take 40 parts, the Radix Rehmanniae, 30 parts, Radix Rehmanniae Preparata, Radix Ophiopogonis 15 parts, Fructus Lycii 15 parts, Semen Cuscutae 15 parts, Herba Ecliptae 12 parts, 7 parts, Fructus Mori, 17 parts, Colla Corii Asini, the Radix Polygoni Multiflori 15 parts, Rhizoma Dioscoreae 25 parts, the Radix Astragali 15 parts, Radix Ginseng 15 parts, Fructus Psoraleae 10 parts, Radix Angelicae Sinensis 8 parts, 17 parts, Poria, 15 parts, Radix Glycyrrhizae, Fructus Ligustri Lucidi 15 parts, Cortex Moutan 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Semen Sesami Nigrum 20 parts, Radix Scrophulariae 15 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Asparagi 15 parts, Herba Agrimoniae 15 parts, Rhizoma Curculiginis 15 parts, Colla Plastri Testudinis 15 parts, Colla cornus cervi 15 parts, Herba Epimedii 15 parts, Placenta Hominis 15 parts, Caulis Spatholobi 10 parts, 10 parts, Radix Notoginseng, Fructus Amomi 10 parts, Herba Cynomorii 10 parts.Above-mentioned weight proportion raw material of Chinese medicine soaks 1 hour after merging, and then decocts 2 hours, filters, obtains filtrate one and medicinal residues; Gained medicinal residues are decocted with water 1 hour again, filters, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, obtains medicine.
Embodiment 4:
Take 40 parts, the Radix Rehmanniae, 40 parts, Radix Rehmanniae Preparata, Radix Ophiopogonis 15 parts, Fructus Lycii 15 parts, Semen Cuscutae 15 parts, Herba Ecliptae 12 parts, 7 parts, Fructus Mori, 17 parts, Colla Corii Asini, the Radix Polygoni Multiflori 15 parts, Rhizoma Dioscoreae 25 parts, the Radix Astragali 15 parts, Radix Ginseng 15 parts, Fructus Psoraleae 8 parts, Radix Angelicae Sinensis 8 parts, 15 parts, Poria, 15 parts, Radix Glycyrrhizae, Fructus Ligustri Lucidi 10 parts, Cortex Moutan 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Semen Sesami Nigrum 25 parts, Radix Scrophulariae 15 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Asparagi 15 parts, Herba Agrimoniae 17 parts, Rhizoma Curculiginis 15 parts, Colla Plastri Testudinis 15 parts, Colla cornus cervi 15 parts, Herba Epimedii 15 parts, Placenta Hominis 15 parts, Caulis Spatholobi 10 parts, 10 parts, Radix Notoginseng, Fructus Amomi 10 parts, Herba Cynomorii 10 parts.Above-mentioned weight proportion raw material of Chinese medicine soaks 1 hour after merging, and then decocts 2 hours, filters, obtains filtrate one and medicinal residues; Gained medicinal residues are decocted with water 1 hour again, filters, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, obtains medicine.
Embodiment 5:
Take 30 parts, the Radix Rehmanniae, 40 parts, Radix Rehmanniae Preparata, Radix Ophiopogonis 15 parts, Fructus Lycii 15 parts, Semen Cuscutae 15 parts, Herba Ecliptae 15 parts, 5 parts, Fructus Mori, 15 parts, Colla Corii Asini, the Radix Polygoni Multiflori 15 parts, Rhizoma Dioscoreae 25 parts, the Radix Astragali 15 parts, Radix Ginseng 15 parts, Fructus Psoraleae 8 parts, Radix Angelicae Sinensis 8 parts, 15 parts, Poria, 15 parts, Radix Glycyrrhizae, Fructus Ligustri Lucidi 10 parts, Cortex Moutan 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Semen Sesami Nigrum 25 parts, Radix Scrophulariae 15 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Asparagi 15 parts, Herba Agrimoniae 17 parts, Rhizoma Curculiginis 15 parts, Colla Plastri Testudinis 15 parts, Colla cornus cervi 15 parts, Herba Epimedii 15 parts, Placenta Hominis 10 parts, Caulis Spatholobi 10 parts, 10 parts, Radix Notoginseng, Fructus Amomi 10 parts, Herba Cynomorii 10 parts.Above-mentioned weight proportion raw material of Chinese medicine soaks 1 hour after merging, and then decocts 2 hours, filters, obtains filtrate one and medicinal residues; Gained medicinal residues are decocted with water 1 hour again, filters, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, obtains medicine.
Embodiment 6:
Take 30 parts, the Radix Rehmanniae, 35 parts, Radix Rehmanniae Preparata, Radix Ophiopogonis 15 parts, Fructus Lycii 15 parts, Semen Cuscutae 15 parts, Herba Ecliptae 15 parts, 5 parts, Fructus Mori, 15 parts, Colla Corii Asini, the Radix Polygoni Multiflori 15 parts, Rhizoma Dioscoreae 25 parts, the Radix Astragali 15 parts, Radix Ginseng 15 parts, Fructus Psoraleae 6 parts, Radix Angelicae Sinensis 6 parts, 15 parts, Poria, 15 parts, Radix Glycyrrhizae, Fructus Ligustri Lucidi 10 parts, Cortex Moutan 10 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Semen Sesami Nigrum 30 parts, Radix Scrophulariae 15 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Asparagi 15 parts, Herba Agrimoniae 17 parts, Rhizoma Curculiginis 15 parts, Colla Plastri Testudinis 15 parts, Colla cornus cervi 15 parts, Herba Epimedii 15 parts, Placenta Hominis 10 parts, Caulis Spatholobi 15 parts, 10 parts, Radix Notoginseng, Fructus Amomi 10 parts, Herba Cynomorii 15 parts.Above-mentioned weight proportion raw material of Chinese medicine soaks 1 hour after merging, and then decocts 2 hours, filters, obtains filtrate one and medicinal residues; Gained medicinal residues are decocted with water 1 hour again, filters, obtain filtrate two and medicinal residues; Filtrate one and filtrate two are merged, obtains medicine.

Claims (3)

1. one kind is used for the treatment of the medicine of aplastic anemia, it is characterized in that, it is made by the raw material of Chinese medicine of following weight: Radix Rehmanniae 30-40 part, Radix Rehmanniae Preparata 30-40 part, Radix Ophiopogonis 10-20 part, Fructus Lycii 10-20 part, Semen Cuscutae 10-20 part, Herba Ecliptae 10-15 part, Fructus Mori 5-10 part, Colla Corii Asini 15-20 part, Radix Polygoni Multiflori 10-20 part, Rhizoma Dioscoreae 20-30 part, Radix Astragali 10-20 part, Radix Ginseng 10-20 part, Fructus Psoraleae 6-10 part, Radix Angelicae Sinensis 6-10 part, Poria 15-20 part, Radix Glycyrrhizae 10-20 part, Fructus Ligustri Lucidi 10-20 part, Cortex Moutan 15-25 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Semen Sesami Nigrum 20-30 part, Radix Scrophulariae 10-20 part, Rhizoma Polygoni Cuspidati 15-25 part, Radix Asparagi 10-20 part, Herba Agrimoniae 15-20 part, Rhizoma Curculiginis 10-20 part, Colla Plastri Testudinis 10-20 part, Colla cornus cervi 10-20 part, Herba Epimedii 10-20 part, Placenta Hominis 10-20 part, Caulis Spatholobi 10-15 part, Radix Notoginseng 10-15 part, Fructus Amomi 10-15 part, Herba Cynomorii 10-15 part.
2. a kind of medicine being used for the treatment of aplastic anemia according to claim 1, it is characterized in that: the weight of each raw material of Chinese medicine is: 35 parts, the Radix Rehmanniae, 35 parts, Radix Rehmanniae Preparata, Radix Ophiopogonis 15 parts, Fructus Lycii 15 parts, Semen Cuscutae 15 parts, Herba Ecliptae 12 parts, 7 parts, Fructus Mori, 17 parts, Colla Corii Asini, the Radix Polygoni Multiflori 15 parts, Rhizoma Dioscoreae 25 parts, the Radix Astragali 15 parts, Radix Ginseng 15 parts, Fructus Psoraleae 8 parts, Radix Angelicae Sinensis 8 parts, 17 parts, Poria, 15 parts, Radix Glycyrrhizae, Fructus Ligustri Lucidi 15 parts, Cortex Moutan 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Semen Sesami Nigrum 25 parts, Radix Scrophulariae 15 parts, Rhizoma Polygoni Cuspidati 20 parts, Radix Asparagi 15 parts, Herba Agrimoniae 17 parts, Rhizoma Curculiginis 15 parts, Colla Plastri Testudinis 15 parts, Colla cornus cervi 15 parts, Herba Epimedii 15 parts, Placenta Hominis 15 parts, Caulis Spatholobi 12 parts, 12 parts, Radix Notoginseng, Fructus Amomi 12 parts, Herba Cynomorii 12 parts.
3. a kind of medicine being used for the treatment of aplastic anemia according to claim 2, is characterized in that: described medicine specifically adopts following step to make:
A takes raw material of Chinese medicine respectively according to above-mentioned weight proportion, soaks 1 hour after merging, then decocts 2 hours, filters, obtains filtrate one and medicinal residues;
Gained medicinal residues in step a are decocted with water 1 hour by b again, filter, obtain filtrate two and medicinal residues;
Filtrate one and filtrate two merge by c, obtain medicine.
CN201510932438.8A 2015-12-15 2015-12-15 Pharmaceutical for treating aplastic anemia Withdrawn CN105456887A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105833203A (en) * 2016-06-05 2016-08-10 王秀芹 Medicine for treating chronic aplastic anemia
CN112891492A (en) * 2021-04-12 2021-06-04 邓来军 Chinese medicinal fleece-flower root marrow-benefiting composition and preparation method of capsule and paste thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
于材声等: "中药生髓补血方合并康力龙治疗慢性再生障碍性贫血39例的疗效观察", 《中医药信息》 *
朱德湘: "温肾益髓汤治疗再生障碍性贫血20例", 《湖南中医杂志》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105833203A (en) * 2016-06-05 2016-08-10 王秀芹 Medicine for treating chronic aplastic anemia
CN112891492A (en) * 2021-04-12 2021-06-04 邓来军 Chinese medicinal fleece-flower root marrow-benefiting composition and preparation method of capsule and paste thereof

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