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CN105343358A - Traditional Chinese medicine capsules for treating coronary heart disease - Google Patents

Traditional Chinese medicine capsules for treating coronary heart disease Download PDF

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Publication number
CN105343358A
CN105343358A CN201510950131.0A CN201510950131A CN105343358A CN 105343358 A CN105343358 A CN 105343358A CN 201510950131 A CN201510950131 A CN 201510950131A CN 105343358 A CN105343358 A CN 105343358A
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heart disease
coronary heart
traditional chinese
chinese medicine
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高松武
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to traditional Chinese medicine capsules for treating a coronary heart disease. The traditional Chinese medicine capsules comprise traditional Chinese medicines by mass as follows: 5 g of ginkgo leaves, 5 g of pseudo ginseng, 5 g of pilose asiabell roots, 4 g of szechuan lovage rhizome, 4 g of Chinese angelica, 3 g of longhairy antenoron herb, 2 g of hiraute shiny bugleweed herb, 2 g of Chinese taxillus twigs, 2 g of grape seeds, 2 g of astragalus membranaceus and 2 g of safflower, wherein the grape seeds are fermented. According to the traditional Chinese medicine capsules, the traditional Chinese medicines are matched, have a good treatment effect on the coronary heart disease and take effect well when used clinically. 38 cases of patients in four years show that the traditional Chinese medicine capsules can effectively treat the coronary heart disease, the effective rate reaches 92.11%, and the capsules also have a good curative effect on rheumatic heart diseases and cardiomyopathy.

Description

A kind of Chinese medicinal capsule for the treatment of coronary heart disease
Technical field
The present invention relates to a kind of Chinese medicinal capsule for the treatment of coronary heart disease, belong to Chinese medicine formula technical field.
Background technology
Coronary atherosclerotic heart disease is coronary artery generation atherosclerotic lesion and causes lumen of vessels stenosis or occlusion, causes myocardial ischemia, anoxia or downright bad and heart disease that is that cause, is usually called as " coronary heart disease ".But the scope of coronary heart disease may be more extensive, also comprises inflammation, thromboembolism etc. and cause luminal stenosis or obturation.Coronary heart disease is divided into 5 large classes by World Health Organization (WHO): silent ischemia (latent coronary heart disease), angina pectoris, myocardial infarction, ischemic heart failure (ischemic heart desease) and sudden death 5 kinds of Clinical types.Stable coronary heart disease and acute coronary syndrome is usually divided in clinical.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicinal capsule for the treatment of coronary heart disease, to treat for patients with coronary heart disease better, improve therapeutic effect.
To achieve these goals, technical scheme of the present invention is as follows.
A kind of Chinese medicinal capsule for the treatment of coronary heart disease, be made up of following Chinese medicine: Folium Ginkgo, Radix Notoginseng, Radix Codonopsis, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Herba Lysimachiae, Herba Lycopi, parasitism, Semen Vitis viniferae, Radix Astragali Flos Carthami, the quality of upper each component is: Folium Ginkgo 5 grams, Radix Notoginseng 5 grams, Radix Codonopsis 5 grams, Rhizoma Chuanxiong 4 grams, Radix Angelicae Sinensis 4 grams, Herba Lysimachiae 3 grams, Herba Lycopi 2 grams, parasitism 2 grams, Semen Vitis viniferae 2 grams, the Radix Astragali 2 grams, 2 grams, Flos Carthami, wherein, Semen Vitis viniferae is the Semen Vitis viniferae after fermentation.
Above-mentioned Chinese medicinal capsule preparation method is: smashed the Chinese medicine of above-mentioned each component to pieces powdered, be prepared into capsule after giving mix homogeneously, every 0.5g or 0.4g.
The concrete instructions of taking of above-mentioned Chinese medicinal capsule is, when the heart state of an illness is not serious, each 5 ~ 6, every day 3 times, takes about 5 days; Move back time every day 3 times, each 4, take about 5 days; Move back time every day 3 times again, each 3.Now enter the program of nourishing heart, if felt heart after 12 days, all have been normal, withdrawal; Because entering the program of nourishing heart, long-term taking.
When above-mentioned Chinese medicinal capsule uses, should be noted that following item:
1) after this medicine takes about two days, chest has pain, is not heart (can try with deep breathing pole) in fact, but chest soft tissue, blood stasis starts from breaking body here and goes out, and this symptom is slept and just substantially disappeared an evening.
2) heart pulse in about 3 days is dynamic obviously strong, and sensation uncomfortable in chest disappears completely, the complete proper flow of promoting the circulation of blood of heart.
3) after, gradually can carry out certain outdoor activities, but sexual life less as well, large motion and ass work wouldn't be applicable to.
4) the smoked deep fried foodstuff of ban on opium-smoking and the opium trade.
5) patient that heart did operation (support, bridging) can use this medicine under the management of doctor.
The herbal function of above-mentioned each tcm components is as follows:
Folium Ginkgo: control chest pain, heart beating is overrun, and reduces blood concentration, vessel softening.
Radix Notoginseng: blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, antithrombotic, heart ischemia, tissue regeneration promoting of enriching blood.
Radix Codonopsis: blood fat reducing, the blood that disappears blocks up, QI invigorating, spleen invigorating.
Rhizoma Chuanxiong: blood-activating and qi-promoting, wind-expelling pain-stopping, changes knot dissipating depression of QI.
Radix Angelicae Sinensis: anti-hypoxia, immunity moderation function, enriches blood and invigorates blood circulation, vessel softening.
Herba Lysimachiae: anti-cardiac-cerebral ischemia, soft blood vessel, diuresis.
Herba Lycopi: invigorate blood circulation, controls blood stasis, antiinflammatory diuresis.
Parasitic: nutrient blood side is empty, invigorating the liver and kidney of nourishing blood.
Semen Vitis viniferae: soft heart cerebrovascular, reduces blood fat, anti-sclerosis.
The Radix Astragali: vessel softening, primordial QI reinforcing reinforcing, adds excitometabolic and gastrointestinal function.
Flos Carthami: invigorating blood circulation can be through, blood stasis removing pain relieving, antithrombotic.
This beneficial effect of the invention is: the Chinese medicinal capsule in the present invention has following effect: antiinflammatory disappears bitterly, and clear thrombosis.Make blood vessel, blood flow obtains proper flow.The operation of complete each function of heart, reinforces cardiovascular greatly, the defensive ability/resistance ability of cardiac muscle.Often take, pathological changes factor can be disappeared in bud in advance, the risk of next time showing effect can be postponed greatly, even no longer occur.All medicines coordinates, and has better therapeutic effect to coronary heart disease, clinical use often receive good effect.In 4 years, by showing the use of 38 patients, this medicine effectively can treat coronary heart disease, and effective percentage reaches 92.11%.This capsule also has good curative effect to rheumatic heart disease and cardiomyopathy.
Detailed description of the invention
Below in conjunction with embodiment, the specific embodiment of the present invention is described, better to understand the present invention.
Embodiment
The Chinese medicinal capsule of the treatment coronary heart disease in the present embodiment, be made up of following Chinese medicine: Folium Ginkgo, Radix Notoginseng, Radix Codonopsis, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Herba Lysimachiae, Herba Lycopi, parasitism, Semen Vitis viniferae, Radix Astragali Flos Carthami, the quality of upper each component is: Folium Ginkgo 5 grams, Radix Notoginseng 5 grams, Radix Codonopsis 5 grams, Rhizoma Chuanxiong 4 grams, Radix Angelicae Sinensis 4 grams, Herba Lysimachiae 3 grams, Herba Lycopi 2 grams, parasitism 2 grams, Semen Vitis viniferae 2 grams, the Radix Astragali 2 grams, 2 grams, Flos Carthami, wherein, Semen Vitis viniferae is the Semen Vitis viniferae after fermentation.
Above-mentioned Chinese medicinal capsule preparation method is: smashed the Chinese medicine of above-mentioned each component to pieces powdered, be prepared into capsule after giving mix homogeneously, every 0.5g or 0.4g.
The concrete instructions of taking of above-mentioned Chinese medicinal capsule is, when the heart state of an illness is not serious, each 5 ~ 6, every day 3 times, takes about 5 days; Move back time every day 3 times, each 4, take about 5 days; Move back time every day 3 times again, each 3.Now enter the program of nourishing heart, if felt heart after 12 days, all have been normal, withdrawal; Because entering the program of nourishing heart, also can long-term taking.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data: inventor have collected 76 routine patients with coronary heart disease between in October ,-2015 in October, 2012 altogether, wherein, 20 years old ~ 50 years old age, 1 month ~ half a year of the state of an illness.Be divided at random: treatment group 38 example, matched group 38 example.The data there was no significant differences such as two groups of ages, have comparability.
2, test method: (1) matched group takes certain city's TONGXINLUO JIAONANG, takes to specifications.21 days courses for the treatment of.(2) the oral capsule of the present invention for the treatment of group, early, middle and late each once.21 days courses for the treatment of.(3) criterion of therapeutical effect and therapeutic outcome: criterion of therapeutical effect: recovery from illness: the clinical symptoms of coronary heart disease all disappears.Take a turn for the better: the clinical symptom relief of coronary heart disease, the state of an illness is controlled.Invalid: the clinical symptoms of coronary heart disease is without being clearly better or increasing the weight of.With recovery from illness and the calculating effective percentage that takes a turn for the better.Treatment statistical result is in table 1.
Table 1 liang group comparitive study
As can be seen here, the medicine adopting prescription of the present invention obtained can safe and effective treatment coronary heart disease.
Toxicity test:
Test drug is the powder in the embodiment of the present invention 2.Experimental animal is ICR kind white mice, body weight 18 ~ 22 grams, male and female half and half, totally 40.Test method is, fasting, after 12 hours, gives mice lavage 4 months by 20 grams/kilogram, and long term toxicity test result shows, white mice body weight, Liver and kidney function, hemogram etc. and matched group no significant difference, shows that the safety of this medicine is large, belongs to nontoxic rank.
The above is the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications are also considered as protection scope of the present invention.

Claims (3)

1. treat the Chinese medicinal capsule of coronary heart disease for one kind, it is characterized in that: be made up of following Chinese medicine: Folium Ginkgo, Radix Notoginseng, Radix Codonopsis, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Herba Lysimachiae, Herba Lycopi, parasitism, Semen Vitis viniferae, Radix Astragali Flos Carthami, the quality of upper each component is: Folium Ginkgo 5 grams, Radix Notoginseng 5 grams, Radix Codonopsis 5 grams, Rhizoma Chuanxiong 4 grams, Radix Angelicae Sinensis 4 grams, Herba Lysimachiae 3 grams, Herba Lycopi 2 grams, parasitism 2 grams, Semen Vitis viniferae 2 grams, the Radix Astragali 2 grams, 2 grams, Flos Carthami, wherein, Semen Vitis viniferae is the Semen Vitis viniferae after fermentation.
2. the Chinese medicinal capsule for the treatment of coronary heart disease according to claim 1, is characterized in that: described Chinese medicinal capsule preparation method is: smashed the Chinese medicine of above-mentioned each component to pieces powdered, be prepared into capsule after giving mix homogeneously, every 0.5g or 0.4g.
3. the Chinese medicinal capsule for the treatment of coronary heart disease according to claim 1, is characterized in that: the concrete instructions of taking of described Chinese medicinal capsule is, when the heart state of an illness is not serious, each 5 ~ 6, every day 3 times, takes 5 days; Move back time every day 3 times, each 4, take 5 days; Move back time every day 3 times again, each 3; Now enter the program of nourishing heart, if felt heart after 12 days, all have been normal, withdrawal; Because entering the program of nourishing heart, also can long-term taking.
CN201510950131.0A 2015-12-18 2015-12-18 Traditional Chinese medicine capsules for treating coronary heart disease Pending CN105343358A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113209283A (en) * 2021-06-03 2021-08-06 绵阳德康疼痛医院 Nerve rehabilitation powder and preparation and use methods thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1030183A (en) * 1987-06-30 1989-01-11 马德林 A kind of manufacture method of preventing and treating the coronary heart disease medicine for external use
CN1726975A (en) * 2005-07-28 2006-02-01 乔国强 Chinese traditional medicine for treating coronar yheart disease an high blood pressure
CN101172141A (en) * 2005-05-24 2008-05-07 马希文 Drug for curing coronary disease
CN101721638A (en) * 2009-11-27 2010-06-09 湖北民康制药有限公司 Oral liquor for treating coronary heart disease
CN102526673A (en) * 2012-02-06 2012-07-04 王健 Chinese medicine capsule, Chinese medicine liquid and health-care oral liquid for treating dilated cardiomyopathy and manufacture method
CN104189668A (en) * 2014-08-01 2014-12-10 济南环太机电技术有限公司 Traditional Chinese medicine composition for treating coronary heart disease

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1030183A (en) * 1987-06-30 1989-01-11 马德林 A kind of manufacture method of preventing and treating the coronary heart disease medicine for external use
CN101172141A (en) * 2005-05-24 2008-05-07 马希文 Drug for curing coronary disease
CN1726975A (en) * 2005-07-28 2006-02-01 乔国强 Chinese traditional medicine for treating coronar yheart disease an high blood pressure
CN101721638A (en) * 2009-11-27 2010-06-09 湖北民康制药有限公司 Oral liquor for treating coronary heart disease
CN102526673A (en) * 2012-02-06 2012-07-04 王健 Chinese medicine capsule, Chinese medicine liquid and health-care oral liquid for treating dilated cardiomyopathy and manufacture method
CN104189668A (en) * 2014-08-01 2014-12-10 济南环太机电技术有限公司 Traditional Chinese medicine composition for treating coronary heart disease

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113209283A (en) * 2021-06-03 2021-08-06 绵阳德康疼痛医院 Nerve rehabilitation powder and preparation and use methods thereof

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Application publication date: 20160224