CN105326659A - Skin-whitening anti-wrinkle essence - Google Patents
Skin-whitening anti-wrinkle essence Download PDFInfo
- Publication number
- CN105326659A CN105326659A CN201510703507.8A CN201510703507A CN105326659A CN 105326659 A CN105326659 A CN 105326659A CN 201510703507 A CN201510703507 A CN 201510703507A CN 105326659 A CN105326659 A CN 105326659A
- Authority
- CN
- China
- Prior art keywords
- parts
- skin
- essence
- wrinkle
- whitening
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000001153 anti-wrinkle effect Effects 0.000 title abstract 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 239000008367 deionised water Substances 0.000 claims abstract description 12
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 12
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims abstract description 11
- 102000008186 Collagen Human genes 0.000 claims abstract description 11
- 108010035532 Collagen Proteins 0.000 claims abstract description 11
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims abstract description 11
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims abstract description 11
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 11
- 230000002087 whitening effect Effects 0.000 claims abstract description 11
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract description 9
- 229930195725 Mannitol Natural products 0.000 claims abstract description 9
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000000594 mannitol Substances 0.000 claims abstract description 9
- 235000010355 mannitol Nutrition 0.000 claims abstract description 9
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229960003987 melatonin Drugs 0.000 claims abstract description 9
- 239000011782 vitamin Substances 0.000 claims abstract description 8
- 235000013343 vitamin Nutrition 0.000 claims abstract description 8
- 229940088594 vitamin Drugs 0.000 claims abstract description 8
- 229930003231 vitamin Natural products 0.000 claims abstract description 8
- 108010075526 keratohyalin Proteins 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 7
- -1 compound vitamin Chemical class 0.000 claims description 8
- 239000002253 acid Substances 0.000 claims description 7
- 239000008176 lyophilized powder Substances 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 3
- 238000007872 degassing Methods 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 18
- 230000037303 wrinkles Effects 0.000 abstract description 10
- 229920001436 collagen Polymers 0.000 abstract description 4
- 230000008929 regeneration Effects 0.000 abstract description 4
- 238000011069 regeneration method Methods 0.000 abstract description 4
- 239000000843 powder Substances 0.000 abstract description 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract description 2
- 229920002674 hyaluronan Polymers 0.000 abstract description 2
- 229960003160 hyaluronic acid Drugs 0.000 abstract description 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002085 irritant Substances 0.000 abstract 1
- 231100000021 irritant Toxicity 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 25
- 229940074410 trehalose Drugs 0.000 description 8
- 230000003020 moisturizing effect Effects 0.000 description 7
- 230000003796 beauty Effects 0.000 description 6
- 239000002537 cosmetic Substances 0.000 description 6
- 235000013305 food Nutrition 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 206010040880 Skin irritation Diseases 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000036556 skin irritation Effects 0.000 description 3
- 231100000475 skin irritation Toxicity 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 241000124008 Mammalia Species 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 2
- 229910021502 aluminium hydroxide Inorganic materials 0.000 description 2
- 229940024545 aluminum hydroxide Drugs 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 210000000170 cell membrane Anatomy 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000002500 effect on skin Effects 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 230000008439 repair process Effects 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 235000019605 sweet taste sensations Nutrition 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- DPVHGFAJLZWDOC-PVXXTIHASA-N (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol;dihydrate Chemical compound O.O.O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 DPVHGFAJLZWDOC-PVXXTIHASA-N 0.000 description 1
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- RSWGJHLUYNHPMX-UHFFFAOYSA-N Abietic-Saeure Natural products C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- 108010022355 Fibroins Proteins 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000001132 Osteoporosis Diseases 0.000 description 1
- 235000005205 Pinus Nutrition 0.000 description 1
- 241000218602 Pinus <genus> Species 0.000 description 1
- KHPCPRHQVVSZAH-HUOMCSJISA-N Rosin Natural products O(C/C=C/c1ccccc1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KHPCPRHQVVSZAH-HUOMCSJISA-N 0.000 description 1
- 208000007107 Stomach Ulcer Diseases 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 229920001222 biopolymer Polymers 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 230000002308 calcification Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229940112822 chewing gum Drugs 0.000 description 1
- 235000015218 chewing gum Nutrition 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 210000000589 cicatrix Anatomy 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 238000002242 deionisation method Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- GXGAKHNRMVGRPK-UHFFFAOYSA-N dimagnesium;dioxido-bis[[oxido(oxo)silyl]oxy]silane Chemical compound [Mg+2].[Mg+2].[O-][Si](=O)O[Si]([O-])([O-])O[Si]([O-])=O GXGAKHNRMVGRPK-UHFFFAOYSA-N 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 208000000718 duodenal ulcer Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000002360 explosive Substances 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 210000002503 granulosa cell Anatomy 0.000 description 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000007917 intracranial administration Methods 0.000 description 1
- 230000004410 intraocular pressure Effects 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 201000002364 leukopenia Diseases 0.000 description 1
- 231100001022 leukopenia Toxicity 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 239000000391 magnesium silicate Substances 0.000 description 1
- 229940099273 magnesium trisilicate Drugs 0.000 description 1
- 229910000386 magnesium trisilicate Inorganic materials 0.000 description 1
- 235000019793 magnesium trisilicate Nutrition 0.000 description 1
- DGMJZELBSFOPHH-KVTDHHQDSA-N mannite hexanitrate Chemical compound [O-][N+](=O)OC[C@@H](O[N+]([O-])=O)[C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)CO[N+]([O-])=O DGMJZELBSFOPHH-KVTDHHQDSA-N 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 210000002752 melanocyte Anatomy 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 210000003463 organelle Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000004223 radioprotective effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 238000001223 reverse osmosis Methods 0.000 description 1
- 239000002884 skin cream Substances 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 description 1
- 229940074409 trehalose dihydrate Drugs 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
- A61K2800/33—Free of surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
- A61K2800/34—Free of silicones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
Skin-whitening anti-wrinkle essence is prepared from, by weight, 2 parts of EGF freeze-dried powder, 17 parts of silk peptides, 23 parts of keratohyalin, 0.7 part of melatonin, 5 parts of collagen, 5 parts of trehalose, 2 parts of compound vitamins, 2 parts of mannitol, 5 parts of hyaluronic acid and the balance deionized water according to a formula, wherein the total weight is 100 parts. The using amount and physical and chemical properties of the raw materials produce the synergic effect, and accordingly the wrinkle-removing, anti-wrinkle and cell regeneration promote effects are achieved. The PH value of the skin-whitening anti-wrinkle essence is approximate to the PH value of the human skin, and the skin-whitening anti-wrinkle essence is non-irritant to the skin. After the skin-whitening anti-wrinkle essence is used, the skin is comfortable and soft, without greasy feeling, and the skin-whitening anti-wrinkle essence has the obvious wrinkle removal, skin restoration, skin whitening and face beautifying effects.
Description
Technical field
The present invention relates to cosmetic field, be specifically related to the whitening anti-wrinkling essence that a kind of wrinkle removing is crease-resistant, promote cell regeneration, to skin, there is good wrinkle removing reparation, the effect of beauty face-whitening-nourishing.
Background technology
Essence is the superfine product in skin care item, composition is exquisite, effect is powerful, Be very effective, remains the noble quality that it has and mystery.Essence, is applicable to any skin or inclined oiliness skin quality, should puts in the vial, take at any time.After essence is used for cosmetic water, before protective skin cream.Essence contains trace element, collagen protein, serum, and its effect has anti-aging, crease-resistant, moisturizing, whitening, removes speckle etc.Essence divides water preparation, oil preparation two kinds, and that extracts is high nutrient and is concentrated.The moisturizing ingredient concentration such as the hyaluronic acid in essence are higher than products such as common astringent, emulsion, facial creams, and concentrated type essence plays a role mainly through massaging, and just should wash after 20 minutes.After using, the skin that collagen is abundant, moisture naturally osmotic, flowing, nutritional labeling absorbing power promotes, and skin water is tender flexible.
Summary of the invention
The object of the present invention is to provide the whitening anti-wrinkling essence that a kind of wrinkle removing is crease-resistant, promote cell regeneration, to skin, there is good wrinkle removing reparation, the effect of beauty face-whitening-nourishing.
Present invention employs such technical scheme: described invention is applicable to the essence of any skin, the raw material in its formula and weight ratio respectively: EGF lyophilized powder 2 parts, silk peptide 17 parts, keratohyalin 23 parts, melatonin 0.7 part, collagen protein 5 parts, trehalose 5 parts, compound vitamin 2 parts, 2 parts, mannitol, transparent angle acid 5 parts, deionized water adds to 100 parts.
Weight proportion of the present invention is through that the present inventor's lot of experiments obtains, and proves to have ideal wrinkle removing reparation, the effect of beauty face-whitening-nourishing to skin reaching in the practical application of 2 years.
Raw material described in the present invention:
EGF lyophilized powder: lyophilized powder has very strong prosthetic, for sensitivity skin, red blood streak or just done the skin after changing the postoperative skin of skin, speckle dispelling have strengthen repair effect.Main uses: Red blood streak dispelling, reparation horny layer, strengthens the thickness of skin; Build up resistance, allow your skin sensitivity no longer come; Repair cicatrix.
Silk peptide: (silkpeptide) is the catabolite of fibroin, is that natural silk is hydrolyzed and obtains under felicity condition.Effect purposes: silk peptide has radioprotective with the absorption preventing leukopenia, reduction human body to metabolism of lipid and cholesterol, promotes the effect such as wound healing and removing toxic substances; When being used as cosmetics additive, silk peptide can provide required nutrient for the homergy of skin and hair, thus increase natural gloss and the elasticity of skin and hair, it to the wetting action of skin and whitening effect also very remarkable, and have and absorb feature that is fast, good film-forming property; Silk peptide also can be used for health toothpaste and soap etc.Silk peptide has the effect suppressing dermal melanin to generate, good skin protection moisturizing and hair care effect.Can be used in cream, frost, emulsion class cosmetics and hair washing, hair care, bath product.
Keratohyalin: be the irregular granule varied in size of a kind of profile seen in the Granulosa cells of mammalian epidermis.Main component: the protein being rich in histidine.
Melatonin: (melatonin), a kind of amine bormones mainly produced by the pinus of mammal and the mankind.Be also called: U.S.A draw ketone peaceful, press down melanocyte, melatonin.Main uses: slow down aging; Resist tumor; Improving water flood; Immunity moderation.
Collagen protein: outer literary fame: collagen.Biopolymer, the main component in animal connective tissue, is also the functional protein that mammal in-vivo content is maximum, distribution is the widest, accounts for 25% ~ 30% of total protein.With the transmission of the formation organized, maturation, cell-tocell, and joint lubrication, wound healing, calcification, blood coagulation and aging etc. have close relationship.Collagen protein is also one of critical raw material of biotech industry most, in all extensive application such as medical material, cosmetics, food industry.
Trehalose: (Trehalosedihydrate), outward appearance: white powder crystallization, is dissolved in hot ethanol, is insoluble to ether.Main uses: trehalose has the effect of stabilate film (cell membrane) and protein structure and resist drying, for its application illustrates wide prospect.Trehalose is applied to biological product protection.In addition, trehalose has the effect suppressing ossein to be decomposed, and thus can be used for improving osteoporosis.Trehalose also can be used to preserve research biological product, as engineered enzyme and other enzyme, cell membrane, antibody, antigen, organelle etc., and food processing, fine chemistry industry etc.
Compound vitamin: (VitaminU, AluminiumHydroxide) is a kind of by vitamin, aluminium hydroxide, magnesium trisilicate making.Indication: be applicable to gastric and duodenal ulcers.
Mannitol: (Mannitol) is the isomers of Sorbitol.Another name: the close alcohol of D-manna; D-mannital; D-C6H14O6.Character: soluble in water, is the solid of white clear, has the sweet taste of similar sucrose.Main uses: mannitol is being pharmaceutically good diuretic, reduces the diluent of intracranial pressure, intraocular pressure and treatment kidney medicine, dehydrant, sugar succedaneum, the excipient being also used as tablet and solid, liquid; In food, the water absorption of these product in sugar and sugar alcohol is minimum, and has tasty and refreshing sweet taste, antiseized for food such as maltose, chewing gum, new year cakes, and is used as the antiseized powder of general cake; Also can be used as the sweeting agent of the low heat values such as diabetics food, body-building food, low sugar; Also for rosin ester processed and artificial glycerol resin, explosive, detonator (nitromannite), in plastics industry, be used as the plasticizer of polrvinyl chloride, in cosmetics, make wetting agent etc.
The acid of transparent angle: time skin most important moisturizing materials, the same with broken uric acid, lactic acid, be the moisturizing acid of skin.
Deionized water: deionized water (deionizedwater) refers to and eliminates the pure water after in ionic species impurity." deionization " that International Organization for Standardization ISO/TC147 specifies is defined as: " deionized water removes ionic species completely or by halves, mainly refers to adopt ion exchange resin treatment method." present technique mainly adopts the method for RO reverse osmosis to produce.
The consumption of each raw material of the present invention and physicochemical property produce coordinative role, and good effect is: wrinkle removing is crease-resistant, promotion cell regeneration.The pH value of pH value and human body skin is close, to no skin irritation; Use obviously to feel comfortably cool afterwards, soft, without greasy feeling, skin is had to the effect of obvious wrinkle removing reparation, beauty face-whitening-nourishing.
Result of use Experimental comparison of the present invention: address: Dengfeng City of Henan Province Dong Guanjie " certain famous brand name cosmetology and health mechanism ".
First group: participate in experiment number 183, be certain famous brand name cosmetology and health mechanism client women, age 18-39 year.Use certain enterprise's reputable brand essence, life cycle is 4 months, on average uses 1-2 time everyone every day.Experimental result: satisfaction rate 66.7%; Be satisfied with standard: obviously to feel comfortably cool after use, soft, without greasy feeling, there is obvious moisturizing effect.
Second group: participate in experiment number 190, be certain famous brand name cosmetology and health mechanism client women, age 18-42 year.Use whitening anti-wrinkling essence of the present invention, life cycle is 4 months, on average uses 1-2 time for each person every day.Experimental result: satisfaction rate 88.5%; Be satisfied with standard: to no skin irritation, use obviously to feel comfortably cool afterwards, soft, without greasy feeling, to skin, there is good wrinkle removing reparation, the effect of beauty face-whitening-nourishing.
Experiment contrast result: whitening anti-wrinkling essence of the present invention, to no skin irritation, use obviously to feel comfortably cool afterwards, soft, without greasy feeling, there is obvious moisturizing effect, to skin, there is good wrinkle removing reparation, the effect of beauty face-whitening-nourishing.
Detailed description of the invention
Described whitening anti-wrinkling essence, the raw material in its formula and weight ratio respectively: EGF lyophilized powder 2 parts, silk peptide 17 parts, keratohyalin 23 parts, melatonin 0.7 part, collagen protein 5 parts, trehalose 5 parts, compound vitamin 2 parts, 2 parts, mannitol, transparent angle acid 5 parts, deionized water adds to 100 parts.Its preparation method is:
Step one: add in appropriate amount of deionized water by EGF lyophilized powder, silk peptide, keratohyalin, melatonin, collagen protein, trehalose, is heated to 75 DEG C of mixing and stirring;
Step 2: by step (one) material degassing, adds wherein by compound vitamin, mannitol and the acid of transparent angle, stirs, then add remaining deionized water, stir, standing 20h finished product.
Claims (2)
1. a whitening anti-wrinkling essence, it is characterized in that, the raw material in formula and weight ratio respectively: EGF lyophilized powder 2 parts, silk peptide 17 parts, keratohyalin 23 parts, melatonin 0.7 part, collagen protein 5 parts, trehalose 5 parts, compound vitamin 2 parts, 2 parts, mannitol, transparent angle acid 5 parts, deionized water adds to 100 parts.
2. according to essence according to claim 1, it is characterized in that, the preparation method of described whitening anti-wrinkling essence is:
Step one: add in appropriate amount of deionized water by EGF lyophilized powder, silk peptide, keratohyalin, melatonin, collagen protein, trehalose, is heated to 75 DEG C of mixing and stirring;
Step 2: by step (one) material degassing, adds wherein by compound vitamin, mannitol and the acid of transparent angle, stirs, then add remaining deionized water, stir, standing 20h finished product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510703507.8A CN105326659A (en) | 2015-10-16 | 2015-10-16 | Skin-whitening anti-wrinkle essence |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510703507.8A CN105326659A (en) | 2015-10-16 | 2015-10-16 | Skin-whitening anti-wrinkle essence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105326659A true CN105326659A (en) | 2016-02-17 |
Family
ID=55277572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510703507.8A Pending CN105326659A (en) | 2015-10-16 | 2015-10-16 | Skin-whitening anti-wrinkle essence |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105326659A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106176459A (en) * | 2016-08-29 | 2016-12-07 | 秦艳红 | A kind of anti-wrinkle essence |
| CN106562915A (en) * | 2016-10-25 | 2017-04-19 | 青岛金达利电子商务有限公司 | Beer moisturizing water-replenishing essence liquid |
-
2015
- 2015-10-16 CN CN201510703507.8A patent/CN105326659A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106176459A (en) * | 2016-08-29 | 2016-12-07 | 秦艳红 | A kind of anti-wrinkle essence |
| CN106562915A (en) * | 2016-10-25 | 2017-04-19 | 青岛金达利电子商务有限公司 | Beer moisturizing water-replenishing essence liquid |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103565728B (en) | A kind of black Fructus Lycii whitening skin and preserving moisture toner/smoothing toner and preparation method thereof | |
| CN103156801B (en) | Whitening tendering skin-maintaining toner and preparing method thereof | |
| CN102525870A (en) | Traditional Chinese medicine beauty mask | |
| CN103705428B (en) | For the nonionic composition and method of making the same of cutin of dispelling | |
| CN104173251A (en) | Whitening mask containing yak ossein peptide and preparation method of whitening mask | |
| CN104906015A (en) | Cubilose whitening and beautifying mask | |
| CN106265439A (en) | Nidus collocaliae white beauty mask only | |
| CN108670901B (en) | A kind of skin softening lotion using macadamia nut protein peptide and green skin extract as active ingredients and preparation method thereof | |
| CN106420482A (en) | Skin energy activating sparkling essence | |
| CN106562904A (en) | Facial mask containing passion fruit extract and preparation method of facial mask | |
| CN104490713A (en) | Super-soft living spring skin care product with functions of removing foul, tightening, resisting wrinkles and activating skin | |
| JP2008255066A (en) | New cosmetic composition for pack | |
| KR100837879B1 (en) | Functional strengthening cosmetic composition containing collagen extracted from deer antler and manufacturing method thereof | |
| RU2410079C1 (en) | Method of eye skin care | |
| CN105326659A (en) | Skin-whitening anti-wrinkle essence | |
| CN103585093B (en) | A kind of moisturizing whitening toner/smoothing toner and preparation method thereof | |
| CN104188854A (en) | Nutritional alcohol-free nourishing astringent lotion | |
| CN114515002A (en) | Combined formula for benefiting qi, nourishing blood, supplementing calcium, maintaining beauty, keeping young and resisting aging | |
| CN104997714A (en) | Tea mask | |
| CN106361676A (en) | External skin-protection cream and preparation method thereof | |
| CN109481323A (en) | A kind of Aloe original juice moisturizing oil and preparation method thereof | |
| CN102266281A (en) | Anti-dandruff anti-itch cream shampoo | |
| CN105012212A (en) | Essence capable of removing acne | |
| CN106389284A (en) | Blacking and nourishing hair mask and preparation method of blacking and nourishing hair mask | |
| CN104887600A (en) | Living cell anti-wrinkling mask |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160217 |