CN105250671A

CN105250671A - Medicine for treating hyperlipoidemia

Info

Publication number: CN105250671A
Application number: CN201510755075.5A
Authority: CN
Inventors: 谢桂斌
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-11-09
Filing date: 2015-11-09
Publication date: 2016-01-20

Abstract

The invention discloses a medicine for treating hyperlipoidemia. The medicine is mainly prepared from the following raw materials in parts by weight: 15-21 parts of Chinese taxillus twig, 15-25 parts of prepared manyflower solomonseal rhizome, 12-18 parts of danshen root, 12-18 parts of tuber fleeceflower root, 12-18 parts of manyflower solomonseal rhizome, 12-18 parts of oriental waterplantain rhizome, 12-18 parts of hawthorn fruit, 15-25 parts of kudzuvine root, 12-18 parts of cassia seed, 10-15 parts of lotus leaf and 12-18 parts of Chinese angelica. The medicine for treating hyperlipoidemia, disclosed by the invention, adopts 11 types of natural traditional Chinese medicines in compatibility and is simple in formula, and all the raw materials act synergistically to achieve the effects of nourishing liver and kidney, reinforcing qi and nourishing blood; the medicine is quick in response, can treat both symptoms and root causes and does not have toxic or side effects; moreover, the preparation method of the medicine is simple, the medicine is convenient to take and is low in cost, and the effective rate is not less than 95%.

Description

Be used for the treatment of the medicine of hyperlipidemia

Technical field

The present invention relates to Chinese medicine, specifically a kind of medicine being used for the treatment of hyperlipidemia.

Background technology

Hyperlipidemia refers to that blood lipid level is too high, directly can cause the disease of some serious harm healths, as atherosclerosis, coronary heart disease, pancreatitis etc.Hyperlipidemia can be divided into constitutional and Secondary cases two class.Constitutional is relevant with heredity with congenital, due to single-gene defect or polygenes defect, make the receptor of the transhipment of participation lipoprotein and metabolism, enzyme or apolipoprotein caused by abnormal, or cause due to environmental factors (diet, nutrition, medicine) with by unknown mechanism.Secondary cases is multiple is born in metabolic disorder disease (diabetes, hypertension, myxedema, hypothyroidism, obesity, hepatorenal disease, adrenal cortex function are hyperfunction), or with other factor age, sex, season, drink, smoking, diet, physical exertion, psychentonia, emotional activity etc. be relevant.The clinical manifestation of hyperlipidemia is the xanthoma of lipid caused by intradermal deposition and the arteriosclerosis of lipid caused by blood vessel endothelium deposition mainly.Although hyperlipidemia can cause xanthoma, its incidence rate is also not bery high; And atherosclerotic generation and development are a kind of slowly progressive processes.Therefore under normal conditions, most of patients non-evident sympton and abnormal sign.Many people raise owing to just finding that there is blood plasma lipoprotein level when other reasons carries out blood biochemical inspection.Dyslipidemia person is often with multiple cardiovascular risk factors.Blood lipid level and decline can make the incidence rate of cardiovascular disease and mortality rate reduce along with the decline of serum total cholesterol and LDL-C level.

Present is main mainly with Western medicine control and treatment, but side effect is comparatively large, and easily recurs, and can not effect a radical cure, cause certain burden to patient's economy and physiology.And the therapeutic efficiency of some current Chinese medicines is also not satisfactory, treatment cycle is long, and curative effect is not remarkable.

Summary of the invention

The object of this invention is to provide the medicine being used for the treatment of hyperlipidemia that a kind of good effect, short treating period, cost are low, have no side effect.

The technical scheme realizing the object of the invention is:

Be used for the treatment of a medicine for hyperlipidemia, the raw material primarily of following weight parts proportioning is made:

Herba Taxilli 15-21 part, Rhizoma Polygonati (processed) 15-25 part, Radix Salviae Miltiorrhizae 12-18 part, Radix Polygoni Multiflori 12-18 part, Rhizoma Polygonati 12-18 part, Rhizoma Alismatis 12-18 part, Fructus Crataegi 12-18 part, Radix Puerariae 15-25 part, Semen Cassiae 12-18 part, Folium Nelumbinis 10-15 part, Radix Angelicae Sinensis 12-18 part.

The above-mentioned medicine being used for the treatment of hyperlipidemia, optimum weight part proportioning of each raw material is:

Herba Taxilli 18 parts, Rhizoma Polygonati (processed) 20 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Polygoni Multiflori 15 parts, Rhizoma Polygonati 15 parts, Rhizoma Alismatis 15 parts, Fructus Crataegi 15 parts, Radix Puerariae 20 parts, Semen Cassiae 15 parts, 12 parts, Folium Nelumbinis, Radix Angelicae Sinensis 15 parts.

Described raw medicinal material is in shop of Chinese medicines and commercially available.

The preparation method of medicine of the present invention is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 30-40min, merges decoction liquor, filter and remove residue, it is the extractum of 1.20-1.30 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.

In the present invention, pharmacology, effect of each crude drug are as follows:

Herba Taxilli: have wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, the effect of antiabortive unit.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, and metrorrhagia is through many, and blood leaking in gestation, frequent fetal movement, has a dizzy spell.

Rhizoma Polygonati (processed): nourishing kidney lung moistening, invigorating the spleen and replenishing QI.For lung-dryness syndrome due to deficiency of YIN, the few expectorant of dry cough, and the chronic cough chronic cough etc. of YIN-deficiency of the lung and kidney; Weakness of the spleen and stomach, both tonifying spleen-yin, again strengthening the spleen gas; Deficiency of kidney essence, dizzy forgetful, soreness of the waist and knees, early whitening of beard and hair and quenching one's thirst.

Radix Salviae Miltiorrhizae: have blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache.

The Radix Polygoni Multiflori: nourishing the blood and yin; Loosening bowel to relieve constipation; Preventing the attack (or recurrence) of malaria; Dispel the wind; Removing toxic substances.Main blood deficiency Light-headedness; Cardiopalmus; Insomnia; The soreness of the waist and knees of the hepatic and renal YIN deficiency; Early whitening of beard and hair; Tinnitus; Seminal emission; Dryness of the intestine constipation; Chronic malaria body is empty; Rubella pruritus; Carbuncle sore; Scrofula; Hemorrhoid.

Rhizoma Polygonati: there is boosting qi and nourishing yin, spleen invigorating, lung moistening, effect of kidney tonifying.Be usually used in deficiency of spleen-QI and stomach-QI, fatigue and asthenia, deficiency of stomach-Yin, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, chronic cough hemoptysis, asthenia of essence and blood, soreness of the waist and knees, early whitening of beard and hair, interior-heat is quenched one's thirst.

Rhizoma Alismatis: promoting diuresis to eliminate damp pathogen, expels the heat-evil, and changes turbid blood fat reducing.For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria, hyperlipemia.

Fructus Crataegi: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, changes turbid blood fat reducing.For meat stagnation, gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, obstruction of qi in the chest and cardialgia, hernia pain, hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation, dysentery is not well.

Radix Puerariae: have expelling pathogenic factors from muscles for reducing heat, rash, promoting the production of body fluid to quench thirst, the merit of yang invigorating antidiarrheal.Be usually used in exterior syndrome heating, stiff nape and back, measles without adequate eruption, calentura is thirsty, and the deficiency of YIN is quenched one's thirst, diarrhea of heat type hematodiarrhoea, diarrhea due to hypofunction of the spleen.

Semen Cassiae: liver heat removing and eyesight improving, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, and constipation can control hypertension and hyperlipidemia.

Folium Nelumbinis: clearing away summer-heat and eliminating dampness, sending up the lucid YANG, cooling blood for hemostasis.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood tells nosebleed, metrorrhagia of having blood in stool.Burnt FOLIUM NELUMBINIS is used for hemorrhage and puerperal blood faints.

Radix Angelicae Sinensis: have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes effect of laxation.

The present invention is used for the treatment of the medicine of hyperlipidemia, and choose 11 kinds of natural Chinese medicine scientific compatibility, formula is simple, each crude drug synergism plays the effect of nourishing the liver and kidney, benefiting QI and nourishing blood, instant effect, treating both the principal and secondary aspects of a disease, have no side effect, and its preparation method is simple, taking convenience, cost is low.

Detailed description of the invention

Below in conjunction with embodiment, content of the present invention is further described, but is not limitation of the invention.

Embodiment 1

Herba Taxilli 15kg, Rhizoma Polygonati (processed) 15kg, Radix Salviae Miltiorrhizae 12kg, Radix Polygoni Multiflori 12kg, Rhizoma Polygonati 12kg, Rhizoma Alismatis 12kg, Fructus Crataegi 12kg, Radix Puerariae 15kg, Semen Cassiae 12kg, Folium Nelumbinis 10kg, Radix Angelicae Sinensis 12kg.

Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 10 times, decoct 30min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 50 DEG C, add adjuvant, make tablet, every sheet 0.1g.

Embodiment 2

Herba Taxilli 18kg, Rhizoma Polygonati (processed) 20kg, Radix Salviae Miltiorrhizae 15kg, Radix Polygoni Multiflori 15kg, Rhizoma Polygonati 15kg, Rhizoma Alismatis 15kg, Fructus Crataegi 15kg, Radix Puerariae 20kg, Semen Cassiae 15kg, Folium Nelumbinis 12kg, Radix Angelicae Sinensis 15kg.

Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 15 times, decoct 35min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 55 DEG C, add adjuvant, make tablet, every sheet 0.2g.

Embodiment 3

Herba Taxilli 21kg, Rhizoma Polygonati (processed) 25kg, Radix Salviae Miltiorrhizae 18kg, Radix Polygoni Multiflori 18kg, Rhizoma Polygonati 18kg, Rhizoma Alismatis 18kg, Fructus Crataegi 18kg, Radix Puerariae 25kg, Semen Cassiae 18kg, Folium Nelumbinis 15kg, Radix Angelicae Sinensis 18kg.

Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 18 times, decoct 38min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 58 DEG C, add adjuvant, make pill, every 0.4g.

Embodiment 4

Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 20 times, decoct 40min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make pill, every 0.5g.

In order to prove the clinical efficacy of Chinese medicine of the present invention further, selecting 200 examples of accepting for medical treatment in patient, clinical observation is carried out to the curative effect of medicine of the present invention.Age 45-70 year, be divided into 4 groups at random, often group be 50 example, be respectively experimental group 1-4 group.

Experimental group 1-4 group takes the medicine of embodiment 1-4 respectively, every day 3 times, each 3 slices/for oral administration, within 7 days, is a course for the treatment of, takes 2 courses for the treatment of continuously.Wherein effective 185 examples, effective 190 examples, cure 182 examples, invalid 10 examples, cure rate 91%, effective percentage 95%.

Claims

1. be used for the treatment of a medicine for hyperlipidemia, it is characterized in that: the raw material primarily of following weight parts proportioning is made:

2. a kind of medicine being used for the treatment of hyperlipidemia according to claim 1, is characterized in that: optimum weight part proportioning of each raw material is:

3. a kind of medicine being used for the treatment of hyperlipidemia according to claim 1, is characterized in that:

Preparation method is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 30-40min, merges decoction liquor, filter and remove residue, it is the extractum of 1.20-1.30 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.