CN105233357A - Disposable plasma mode separation tubing - Google Patents

Abstract

The invention provides a disposable plasma mode separation pipeline, including a plasma mode primary separation pipeline and a plasma mode secondary separation pipeline, mainly composed of an arterial end blood line tube, a venous end blood line tube, a plasma replenishment line, and a plasma separation waste liquid It is composed of a slurry discarding pipeline, a filter pressure measuring pipeline, a waste plasma circuit connected to a waste liquid bag and a waste liquid bag for preflushing. The invention has a reasonable design and solves the problems of insufficient operation and easy pollution in the original disposable blood plasma separation pipeline. It can be administered directly, avoiding puncture administration on peripheral blood vessels, reducing the pain of patients, adding waste liquid bags, no need to prepare waste liquid buckets during preflushing and treatment, and waste liquids are directly discharged into waste liquid bags, avoiding possible lead to pollution problems. The invention realizes fully-closed preflushing, thereby making the operation easier and safer. The problem of possible cross-infection is avoided. The invention is simple, convenient and standard in use, and has low use cost.

Description

Disposable plasma mode separation tubing

technical field

The invention belongs to the category of medical instruments, and relates to a disposable blood plasma mode separation pipeline.

Background technique

Plasma pattern separation is divided into membrane-type primary separation and pattern secondary separation. The plasma pattern primary separation is the main treatment for diseases such as severe liver failure and drug poisoning, and the plasma pattern secondary separation is for severe immune diseases and partial renal failure. The patient population has high antibodies and needs the necessary preparations before kidney transplantation and the main treatment for rejection after kidney transplantation. When plasmapheresis is performed, the doctor first establishes the patient's vascular access, and then puts the pre-washed separator and the disposable The blood line is connected to the patient's vascular access, and extracorporeal circulation is established to start the plasma separation treatment.

The original one-time-use plasma mode separation pipeline is mainly composed of: 1. Blood line tube at the arterial end (including 2 infusion connectors on the blood line before the pump, pump tube, heparin tube and degassing bottle on the blood line after the pump, and Arterial pressure test connector); 2. Venous blood line tube (including degassing pot, venous pressure test path), and accessories (including: blood line tube clips before the pump, blood line tube clips after the pump, and infusion connector clips at each end, etc.); 3. Plasma separation circuit (pump tube, degassing pot and pressure measuring joint); 4. Plasma return circuit (including pump tube, filter joint and heating tube on the pipeline after the pump, etc.); 5. Plasma discarding circuit—secondary Used for separation (including pump tube and arterial pressure test connector); 6. Other auxiliary circuits. When pre-flushing the blood line before treatment and during the end of treatment, an additional waste bucket should be prepared, and the infusion set should be connected to the infusion connector of the blood line before the pump for pre-flushing and blood return. When preflushing, clamp the port of the discarded pulp circuit, the port of the pulp return circuit and the port of the blood pipe behind the pump on the edge of the waste bucket.

The defects of the above-mentioned structure are: 1. When using the original disposable plasma mode separation circuit for treatment, there is no port on the venous circuit for drug administration when medication is needed, and the operation cannot be performed directly, and the drug must be punctured on the peripheral blood vessel. , not only time-consuming and labor-intensive, but also increased patient pain. 2. When the nurse pre-flushes the blood tube, it is impossible to avoid the slipping of the three tube ports clamped on the edge of the waste bucket, and fall into the waste bucket by mistake, which directly leads to the pollution of the blood tube port; during the treatment process, the nurse puts the Discarded plasma is easily polluted if it is placed in the waste bin openly. 3. When using the original disposable plasma mode separation pipeline to return blood, it cannot be operated directly. It is necessary to connect a pair of infusion sets of the auxiliary circuit to the infusion joint of the blood line in front of the pump, which increases the chance of contamination due to improper operation. .

Contents of the invention

The purpose of the present invention is to provide a simple and safe disposable plasma separation pipeline, which mainly solves the problems of insufficient operation and easy pollution in the original disposable plasma separation pipeline.

The plasma mode separation pipeline of the present invention includes a plasma mode primary separation pipeline (PE type) and a plasma mode secondary separation pipeline (DFPP type), wherein the plasma mode primary separation pipeline (PE type): consists of arterial end blood line tube A, It consists of blood line tube B at the venous end, plasma replenishment line C, plasma separation waste liquid disposal line D, filter pressure measurement line E, waste plasma circuit connection waste liquid bag F, and waste liquid bag G for preflushing. Then connect port A5 of the arterial end blood line A, port B5 of the venous end blood line B, and port C2 of the plasma replenishment line C with the three ports of the preflush waste bag G respectively, and discard the plasma separation waste tube The port D2 of the circuit D is connected to the waste plasma circuit connection waste liquid bag F, and then put into the outer packaging bag together with the pressure measuring line E of the filter, and is sterilized with ethylene oxide after the whole is sealed. The selected capacity of the waste plasma circuit connected to the waste liquid bag F is about 3000ml.

Plasma mode secondary separation pipeline (DFPP blood type): consists of arterial terminal pipeline A, venous terminal pipeline B, plasma separation waste liquid disposal pipeline C, plasma replenishment pipeline D, plasma component separation pump tube E, filter tester It is composed of pressure pipeline F (2 pieces), waste plasma circuit connecting waste liquid bag G and waste liquid bag H for preflushing. Then connect the port A5 of the arterial end line A, the port B5 of the venous end line B, the port C2 of the plasma separation waste liquid disposal line C, and the port of the plasma replenishment line D with the 4 ports of the waste liquid bag H for preflushing respectively. Connect the two ports, connect the port E2 of the plasma component separation pump tube E to the waste plasma circuit connection waste liquid bag G, and then put it into the outer packaging bag together with the filter pressure measuring line F (2 pieces), and seal it as a whole Sterilize with ethylene oxide. The capacity of the waste plasma circuit connected to the waste liquid bag G is 1000ml.

The beneficial effects of the present invention are: (1) Add a small tube port for administration and an administration port for acupuncture on the degassing pot of the blood line tube at the venous end, so that the drug can be administered directly from here, avoiding puncture on peripheral blood vessels Drug administration is easier and safer, and the patient's pain is reduced. (2) A waste liquid bag connected to the port of the blood line tube at the arterial end, the port of the plasma return circuit tube, and the port of the discarded plasma circuit tube is added. When pre-flushing, nurses do not need to prepare additional waste liquid buckets, and the pre-flush waste liquid is directly discharged into the waste water. In the liquid bag, the problem of pollution caused by the original blood tube port slipping off and falling into the waste liquid bucket is avoided. (3) A waste liquid bag connected to the port of the discarded plasma circuit pipe is added. During the treatment, the nurse does not need to prepare an additional waste liquid bucket, and the discarded plasma is directly discharged into the waste liquid bag, avoiding the problem that may cause pollution. (4) The present invention realizes the concept of fully-closed preflushing of the one-time-use plasma mode separation pipeline. The new disposable plasma mode separation pipeline adds an integrated infusion set, which can be directly operated when the blood returns after treatment, without the need for Additional preparation of infusion sets makes it easier and safer. (5) The problem of possible cross-infection in the process of cleaning and disinfecting the waste liquid barrel is avoided. (6) After cost calculation, the present invention is more economical than the original disposable hemodialysis tubing.

Description of drawings

Figure 1 is a schematic diagram of the primary separation pipeline in the PE type plasma mode.

Figure 2 is a schematic diagram of the combination in the PE-type plasma mode primary separation tubing bag.

Fig. 3 is a schematic diagram of the structure of the secondary separation pipeline in the DFPP type plasma mode.

Fig. 4 is a schematic diagram of the combination in the packaging bag of the DFPP type plasma mode secondary separation pipeline.

detailed description

The present invention is described further by accompanying drawing and embodiment.

Example 1

Referring to Fig. 1 and Fig. 2, the plasma mode primary separation pipeline (PE type) of the present invention consists of arterial end blood line A, venous end blood line B, plasma replenishment line C, plasma separation waste liquid disposal line D, filter The pressure measuring pipeline E, the waste plasma circuit connecting the waste liquid bag F and the waste liquid bag G for preflushing are composed. Then connect port A5 of the arterial end blood line A, port B5 of the venous end blood line B, and port C2 of the plasma replenishment line C with the three ports of the preflush waste bag G respectively, and discard the plasma separation waste tube The port D2 of the circuit D is connected to the waste plasma circuit connection waste liquid bag F, and then put into the outer packaging bag together with the pressure measuring line E of the device, and is sterilized with ethylene oxide after the whole is sealed. The selected capacity of the waste plasma circuit connected to the waste liquid bag F is about 3000ml.

Example 2

Referring to Fig. 3 and Fig. 4, the plasma mode secondary separation pipeline (DFPP type blood) of the present invention consists of arterial end pipeline A, venous end pipeline B, plasma separation waste liquid discarding pipeline C, plasma replenishment pipeline D, Plasma component separation pump tube E, filter pressure measuring pipeline F (2 pieces), waste plasma circuit connection waste liquid bag G and waste liquid bag H for preflushing. Then connect the port A5 of the arterial end line A, the port B5 of the venous end line B, the port C2 of the plasma separation waste liquid disposal line C, and the port of the plasma replenishment line D with the 4 ports of the waste liquid bag H for preflushing respectively. Connect the two ports, connect the port E2 of the plasma component separation pump tube E to the waste plasma circuit connection waste liquid bag G, and then put it into the outer packaging bag together with the filter pressure measuring line F (2 pieces), and seal it as a whole Sterilize with ethylene oxide. The capacity of the waste plasma circuit connected to the waste liquid bag G is 1000ml.

Example 3

See Figure 1, the plasma mode primary separation pipeline (PE type) is used to connect the patient and the plasma mode separation machine. Before the start of the plasma separation treatment, in order to pre-flush the plasma mode primary separation line (Figure 1) and the plasma separator, the nurse must connect the plasma mode primary separation line with the plasma separator, and then install it to the plasma mode separation line. on the machine, and place the pre-flush waste bag G uniformly in the clean area (not on the ground), take the infusion set (port A2) before the arterial blood line pump in the arterial blood line A or the blood line B of the venous end. The integrated infusion set (port B2) on the air bottle is connected to the pre-flush solution, and the clip of the infusion set is opened to start pre-flush, and the pre-flush waste liquid is discharged into the waste bag G. Before the first separation treatment in plasma mode, connect the discarding tube D to the waste liquid bag F, and discharge the discarded plasma during the treatment into the waste liquid bag; after the first separation treatment in plasma mode, clamp the front pump tube at the arterial end Open the clamp of the infusion set and the blood pump to return a little blood, turn off the pump and open the arterial line, return the blood from the arterial line into the body, and then clamp the line before the pump at the arterial end; then drain the blood in the plasma separator and the venous line back into the body.

The plasma mode primary separation pipeline (PE type) of the present invention adds a small tube port for administration (B3) and a needle administration port on the degassing pot of the blood line at the venous end, from which the drug can be administered directly; in addition, the arterial The port (A5) of the end blood line tube, the port (B5) of the venous end blood line tube and the port (C2) of the plasma replenishment line are respectively connected to the three ports of the preflush waste bag G, and the The waste bag is used for priming. Another waste liquid bag F is connected with the plasma separation waste liquid waste slurry pipeline to collect waste plasma during treatment. One infusion connector of the pre-pump blood line of arterial end blood line A is improved to a pair of integrated infusion set (port A2) connected to the blood line, which can be used directly when the blood is returned after treatment. And add an integrated infusion set (port B2) connected to the blood line to the degassing pot of the venous blood line B. All pump tubing must be greater than or equal to 30cm.

Example 4

See Figure 3, the plasma mode secondary separation pipeline (DFPP type) is used to connect the patient and the plasma mode separation machine. Before the start of the plasma mode secondary separation treatment, in order to pre-flush the disposable plasma mode secondary separation line and the plasma separator, the nurse must connect the plasma mode secondary separation line (Figure 3) with the plasma separator, and then install Go to the plasma mode separation machine, and place the pre-flush waste bag H in a clean area (not on the ground), and take the arterial end pump integrated infusion set (port A2) of the arterial end line A or the venous end line B Connect the pre-flush to the integrated infusion set (port B2) on the degassing pot, open the clamp, and start pre-flush, and the pre-flush waste liquid is discharged into the waste liquid bag H. Before the plasma mode secondary separation treatment, connect the plasma separation waste liquid waste line C to the waste plasma circuit connection waste liquid bag G, and discharge the waste plasma during the treatment into the waste liquid bag; the plasma mode secondary separation treatment After the end, clamp the pre-pump line at the arterial end, open the clamp of the infusion set and the blood pump to return a little blood, turn off the pump and open the arterial line, return the blood from the arterial line into the body, and then clamp the pre-pump line at the arterial end; The blood in the plasma separator and the venous line returns to the body.

The plasma mode secondary separation pipeline (DFPP type) of the present invention adds a thin tube port for administration (B3) and an acupuncture administration port on the degassing pot of the venous end circuit B, and can directly administer medicine from here; in addition Connect the port (A5) of the arterial line A, the port (B5) of the venous line B, the port (C2) of the plasma separation waste line C, and the port (D2) of the plasma replenishment line D with the preset The four ports of the flushing waste bag H are connected, and the waste liquid bag H connected with the pipeline is used for preflushing. Another waste liquid bag G is connected with the port (C2) of the plasma separation waste liquid waste line C to collect waste plasma during treatment. One infusion connector of the pre-pump blood line of the arterial line A is improved to a pair of integrated infusion set (port A2) connected with the blood line, which can be used directly when the blood is returned at the end of treatment; An integrated infusion set (port B2) connected to the blood line is added to the air bottle. All pump tubing must be greater than or equal to 30cm.

Claims (6)

1. a disposable blood plasma modal cutoff pipeline, it is characterized in that, comprise plasma profile first separation pipeline and plasma profile secondary separation pipeline, wherein plasma profile first separation pipeline is abandoned slurry pipeline (D), filter pressure measurement pipeline (E), discarded plasma circuit connection waste fluid bag (F) and pre-punching waste fluid bag (G) formed by arterial end blood vessel (A), vein end blood vessel (B), plasma supplemented pipeline (C), blood plasma separation waste liquid; Plasma profile secondary separation pipeline is separated waste liquid pipe abandon road (C), plasma supplemented pipeline (D), plasma fraction separation pump line (E), filter pressure measurement pipeline (F), discarded plasma circuit connection waste fluid bag (G) and pre-punching waste fluid bag (H) is formed by arterial end pipeline (A), vein end pipeline (B), blood plasma, and all Diameter of pump tube are more than or equal to 30cm.

2. one according to claim 1 disposable blood plasma modal cutoff pipeline, it is characterized in that, by the port (A5) of arterial end blood vessel (A) in plasma profile first separation pipeline, the port (B5) on vein end blood vessel road (B), the port (C2) of plasma supplemented pipeline (C) is connected with 3 ports rushing waste fluid bag (G) in advance respectively, the port (D2) blood plasma being separated waste liquid pipe abandon road (D) is connected waste fluid bag (F) and is connected with discarded plasma circuit, outer packaging bag is put into again together with filter pressure measurement pipeline (E), ethylene oxide sterilizing is adopted after integral sealing.

3. one according to claim 1 disposable blood plasma modal cutoff pipeline, it is characterized in that, by the port (A5) of arterial end pipeline (A) in plasma profile secondary separation pipeline, the port (B5) of vein end pipeline (B), blood plasma is separated the port (C2) on waste liquid pipe abandon road (C), the port (D2) of plasma supplemented pipeline (D) is connected with 4 ports of pre-punching waste fluid bag (H) respectively, the port (E2) plasma fraction being separated pump line (E) is connected waste fluid bag (G) and is connected with discarded plasma circuit, outer packaging bag is put into again together with filter pressure measurement pipeline (F), ethylene oxide sterilizing is adopted after integral sealing.

4. one according to claim 1 disposable blood plasma modal cutoff pipeline, is characterized in that, described filter pressure measurement pipeline (F) selects 2.

5. one according to claim 1 and 2 disposable blood plasma modal cutoff pipeline, is characterized in that, in plasma profile first separation pipeline, discarded plasma circuit connection waste fluid bag (F) selects capacity 3000ml.

6. the disposable blood plasma modal cutoff of the one according to claim 1 or 3 pipeline, is characterized in that, in plasma profile secondary separation pipeline, discarded plasma circuit connection waste fluid bag (G) selects capacity 1000ml.