CN105233258A - Composition for removing acne - Google Patents
Composition for removing acne Download PDFInfo
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- CN105233258A CN105233258A CN201510794735.0A CN201510794735A CN105233258A CN 105233258 A CN105233258 A CN 105233258A CN 201510794735 A CN201510794735 A CN 201510794735A CN 105233258 A CN105233258 A CN 105233258A
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- epidermal growth
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- 206010000496 acne Diseases 0.000 title abstract description 11
- 208000002874 Acne Vulgaris Diseases 0.000 title abstract description 7
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- 229940116978 human epidermal growth factor Drugs 0.000 claims abstract description 25
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- 239000002994 raw material Substances 0.000 claims abstract description 13
- 230000003255 anti-acne Effects 0.000 claims description 38
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Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the technical field of traditional Chinese medicines, and in particular relates to a composition for removing acne. The composition is prepared from the following raw materials in parts by weight: 5-15 parts of alpinia katsumadai, 6-12 parts of humifuse euphorbia herb, 5-12 parts of cortex ailanthic, 8-15 parts of the bark of ash, 6-13 parts of ardisia crenata roots, 5-12 parts of peanut coat, 4-11 parts of caulis aristolochiae manshuriensis and 0.001-0.005 part of a recombinant human epidermal growth factor. The composition for removing acne can treat both symptoms and root causes and is remarkable in acne removing effect and short in treatment period, and the disease does not reoccur.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly a kind of compositions of anti-acne.
Background technology
Small pox is commonly called as comedo, be acne again, its morbidity had nothing to do with the age, it is a kind of multifactorial disease, its morbidity is main and sex hormone level, sebaceous gland are secreted in a large number, small pox propionibacterium is bred, the factors such as the dyskeratosis of pilosebaceous duct and inflammation are correlated with, also relevant with living habit, dietary habit, psychological factor, environmental factors, Endocrine hormone levels and inherited genetic factors; In addition to the above, with regard to women, the appearance of comedo is also relevant with the improper use of cosmetics, and gastrointestinal function is bad also can cause comedo problem.
Acne is mainly in face, has a strong impact on looks, brings great thought pressure to patient's job hunting, friend-making, life.Existing anti-acne method is of a great variety, has various acne-eliminating cosmetic, anti-acne medicine for external use, anti-acne oral medicine, also comprises various Chemical peeling, naturopathy.But product for resolving poxes external effect is poor, and dependency is stronger; Anti-acne Western medicine is many containing antibiotic, and side effect is comparatively large, and long-term taking increases the weight of liver, kidney burden; Chemical peeling, naturopathy need Repeated Operation, somewhat expensive, and effect is general; Existing anti acne of traditional Chinese medicine compositions medicine time is long, it is slow to take effect, easily recurrence, can not reach the effect for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Technical problem to be solved by this invention is to provide the compositions of anti-acne, its treating both the principal and the secondary aspects of a disease at the same time, and anti-acne effect is remarkable, and the cycle of curing is short, does not recur.
For achieving the above object, the present invention adopts following technical scheme:
The invention provides a kind of compositions of anti-acne, be made up of the raw material of following weight portion: Semen Alpiniae Katsumadai 5 ~ 15 parts, Herba Euphorbiae Humifusae 6 ~ 12 parts, Cortex Ailanthi 5 ~ 12 parts, Cortex Fraxini 8 ~ 15 parts, Radix Ardisiae Crenatae 6 ~ 13 parts, Testa arachidis hypogaeae 5 ~ 12 parts, Caulis Aristolochiae Manshuriensis 4 ~ 11 parts, recombinant human epidermal growth factor 0.001 ~ 0.005 part.
Further, the compositions of anti-acne of the present invention, be made up of the raw material of following weight portion: Semen Alpiniae Katsumadai 7 ~ 11 parts, Herba Euphorbiae Humifusae 8 ~ 10 parts, Cortex Ailanthi 7 ~ 10 parts, Cortex Fraxini 11 ~ 13 parts, Radix Ardisiae Crenatae 8 ~ 10 parts, Testa arachidis hypogaeae 6 ~ 10 parts, Caulis Aristolochiae Manshuriensis 6 ~ 8 parts, recombinant human epidermal growth factor 0.002 ~ 0.004 part.
A more step ground, the compositions of anti-acne of the present invention, is made up of the raw material of following weight portion: Semen Alpiniae Katsumadai 9 parts, Herba Euphorbiae Humifusae 9 parts, Cortex Ailanthi 8 parts, Cortex Fraxini 12 parts, Radix Ardisiae Crenatae 9 parts, Testa arachidis hypogaeae 8 parts, Caulis Aristolochiae Manshuriensis 7 parts, recombinant human epidermal growth factor 0.003 part.
In raw material of the present invention, the circulation of qi promoting of Semen Alpiniae Katsumadai dampness; Herba Euphorbiae Humifusae heat-clearing and toxic substances removing, promoting blood circulation and hemostasis, dampness removing jaundice eliminating; Cortex Ailanthi, heat clearing and damp drying, hemostasis leukorrhagia stopping; Cortex Fraxini heat-clearing and toxic substances removing, dampness-eliminating and dysentery-stopping; Radix Ardisiae Crenatae heat-clearing and toxic substances removing, eliminating stasis to stop pain; Testa arachidis hypogaeae astringing to arrest bleeding; Caulis Aristolochiae Manshuriensis clearing away heat and promoting diuresis is treating stranguria; Recombinant human epidermal growth factor has anti-inflammatory analgesic, the growth of effective low promotion and reconciliation statement chrotoplast and propagation.
Beneficial effect of the present invention is:
1, the present invention adopts Common Chinese Herbs and recombinant human epidermal growth factor rational proportion, can clearing away heat and cooling blood, suppresses Propiobacterium, suppresses pilosebaceous unit growth of microorganism; Reduce seborrhea rate, reduce serum free fatty acid, reduce sebum secretion, effective anti-acne; Can anti-pilosebaceous duct keratinization, suppress pilosebaceous duct hyperkeratosis, reduce small pox sickness rate; Can reduce the level of body Pro-inflammatory mediator IL-6 and IL-8, control agent internal hormone is secreted, and reduce inflammation reaction, improves anti inflammatory immunity; Promote emiocytosis hyaluronic acid and glycoprotein, Reasonable adjustment skin texture, suppress the growth of small pox, improve skin quality.
2, Semen Alpiniae Katsumadai of the present invention, Herba Euphorbiae Humifusae, Cortex Ailanthi, Cortex Fraxini 12, Radix Ardisiae Crenatae, Testa arachidis hypogaeae and Caulis Aristolochiae Manshuriensis, can ensure the stability of recombinant human epidermal growth factor, prevents it from degrading, and keeps it active.
3, the present invention adopt orally to effect a permanent cure, outer wiping takes stopgap measures, the Chinese traditional medicine principle for the treatment of both the principal and secondary aspects of a disease, have instant effect, effective, have no side effect, no dependence, the advantage such as not recur.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described, but the present invention is not limited to these embodiments.
Embodiment 1
The compositions of anti-acne, is made up of the raw material of following weight portion: Semen Alpiniae Katsumadai 5 parts, Herba Euphorbiae Humifusae 12 parts, Cortex Ailanthi 5 parts, Cortex Fraxini 15 parts, Radix Ardisiae Crenatae 6 parts, Testa arachidis hypogaeae 12 parts, Caulis Aristolochiae Manshuriensis 4 parts, recombinant human epidermal growth factor 0.005 part.
Chinese medicine ingredients in the compositions of anti-acne conveniently prepares the method preparation of Chinese medicine, is prepared into unguentum, then adds recombinant human epidermal growth factor mix homogeneously.
Embodiment 2
The compositions of anti-acne, is made up of the raw material of following weight portion: Semen Alpiniae Katsumadai 7 parts, Herba Euphorbiae Humifusae 10 parts, Cortex Ailanthi 7 parts, Cortex Fraxini 13 parts, Radix Ardisiae Crenatae 8 parts, Testa arachidis hypogaeae 10 parts, Caulis Aristolochiae Manshuriensis 6 parts, recombinant human epidermal growth factor 0.002 part.
Chinese medicine ingredients in the compositions of anti-acne conveniently prepares the method preparation of Chinese medicine, is prepared into unguentum, then adds recombinant human epidermal growth factor mix homogeneously.
Embodiment 3
The compositions of anti-acne, is made up of the raw material of following weight portion: Semen Alpiniae Katsumadai 9 parts, Herba Euphorbiae Humifusae 9 parts, Cortex Ailanthi 8 parts, Cortex Fraxini 12 parts, Radix Ardisiae Crenatae 9 parts, Testa arachidis hypogaeae 8 parts, Caulis Aristolochiae Manshuriensis 7 parts, recombinant human epidermal growth factor 0.003 part.
Chinese medicine ingredients in the compositions of anti-acne conveniently prepares the method preparation of Chinese medicine, is prepared into unguentum, then adds recombinant human epidermal growth factor mix homogeneously.
Embodiment 4
The compositions of anti-acne, is made up of the raw material of following weight portion: Semen Alpiniae Katsumadai 11 parts, Herba Euphorbiae Humifusae 8 parts, Cortex Ailanthi 10 parts, Cortex Fraxini 11 parts, Radix Ardisiae Crenatae 10 parts, Testa arachidis hypogaeae 6 parts, Caulis Aristolochiae Manshuriensis 8 parts, recombinant human epidermal growth factor 0.004 part.
Chinese medicine ingredients in the compositions of anti-acne conveniently prepares the method preparation of Chinese medicine, is prepared into unguentum, then adds recombinant human epidermal growth factor mix homogeneously.
Embodiment 5
The compositions of anti-acne, is made up of the raw material of following weight portion: Semen Alpiniae Katsumadai 15 parts, Herba Euphorbiae Humifusae 6 parts, Cortex Ailanthi 12 parts, Cortex Fraxini 8 parts, Radix Ardisiae Crenatae 13 parts, Testa arachidis hypogaeae 5 parts, Caulis Aristolochiae Manshuriensis 11 parts, recombinant human epidermal growth factor 0.001 part.
Chinese medicine ingredients in the compositions of anti-acne conveniently prepares the method preparation of Chinese medicine, is prepared into unguentum, then adds recombinant human epidermal growth factor mix homogeneously.
Test example 1: the compositions of anti-acne of the present invention is to the clinical efficacy of anti-acne
1, clinical data: random selecting 13-30 year comedo patient 480 example, its mean age is 19 years old, wherein male 264 example, women 216 example.
2, Therapeutic Method:
480 routine patients are divided into 6 groups at random, often organize 80 examples, often organize the difference oral embodiment of the present invention 1, embodiment 2, embodiment 3, embodiment 4, embodiment 5, (formula is comparative example: Semen Alpiniae Katsumadai 9 parts, Herba Euphorbiae Humifusae 9 parts, Cortex Ailanthi 8 parts, Cortex Fraxini 12 parts, Radix Ardisiae Crenatae 9 parts, Testa arachidis hypogaeae 8 parts, Caulis Aristolochiae Manshuriensis 7 parts).
For oral administration: to get medicine of the present invention (except recombinant human epidermal growth factor), add 1000mL water, decoct 2-3 hour, be cooled to room temperature, add recombinant human epidermal growth factor mix homogeneously, take, take every morning once, 3 days courses for the treatment of, take 4 courses for the treatment of altogether.
Outer painting: the medicinal residues of being boiled medicine morning, adds 500mL water soaking, filters medicinal residues just before going to bed, add recombinant human epidermal growth factor mix homogeneously, obtain medicinal liquid, first the place of long pox is cleaned up, then dip medicinal liquid with sterile gauze and spread on affected part, clean up after half an hour.
3, efficacy assessment standard:
Recovery from illness: pox scar pox print disappears, skin smooth finish, drug withdrawal nothing recurrence in 3 months;
Effective: total skin lesion number obviously reduces;
Invalid: clinical symptoms is without significant change, and total skin lesion number is without minimizing.
4, therapeutic outcome:
The clinical observation of table 1 embodiment 1 ~ 5 pair of anti-acne
| Sequence number | Number of cases | Recovery from illness | Effectively | Invalid | Effective percentage | Recurrence |
| Embodiment 1 | 80 | 53 | 27 | 0 | 100％ | 0 |
| Embodiment 2 | 80 | 57 | 22 | 1 | 98.75％ | 0 |
| Embodiment 3 | 80 | 59 | 21 | 0 | 100％ | 0 |
| Embodiment 4 | 80 | 56 | 22 | 2 | 97.5％ | 0 |
| Embodiment 5 | 80 | 55 | 24 | 1 | 98.75％ | 0 |
| Comparative example | 80 | 35 | 38 | 7 | 91.25％ | 2 |
As can be seen from Table 1, the Be very effective of the embodiment of the present invention 1 ~ 5 anti-acne, effective percentage reaches more than 97.5%, and significantly and do not recur, time in formula containing recombinant human epidermal growth factor, effective percentage declines anti-acne effect, also there will be rebound phenomenon.
The curative effect clinical observation course for the treatment of of table 2 embodiment 1 ~ 5 pair of anti-acne
As can be seen from Table 2, in healing example, ratio shared by 1 healing course for the treatment of of the embodiment of the present invention 1 ~ 5 anti-acne is high, and it is less to cure 4 courses for the treatment of proportion, illustrate that the embodiment of the present invention 1 ~ anti-acne time used is short, and when not containing recombinant human epidermal growth factor in formula, cure in example, 2 large percentages of curing the course for the treatment of.
Test example 3: the compositions active testing data of anti-acne of the present invention
The compositions of the anti-acne of the present invention's 5 embodiments is regularly carried out active testing, obtains the result as following table 3:
The compositions active testing data of table 3 anti-acne of the present invention
As can be seen from data above, the compositions activity-maintaining time of anti-acne of the present invention is permanent, and lasting rate at least can reach 3 years.
Claims (3)
1. the compositions of an anti-acne, it is characterized in that, be made up of the raw material of following weight portion: Semen Alpiniae Katsumadai 5 ~ 15 parts, Herba Euphorbiae Humifusae 6 ~ 12 parts, Cortex Ailanthi 5 ~ 12 parts, Cortex Fraxini 8 ~ 15 parts, Radix Ardisiae Crenatae 6 ~ 13 parts, Testa arachidis hypogaeae 5 ~ 12 parts, Caulis Aristolochiae Manshuriensis 4 ~ 11 parts, recombinant human epidermal growth factor 0.001 ~ 0.005 part.
2. the compositions of anti-acne according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: Semen Alpiniae Katsumadai 7 ~ 11 parts, Herba Euphorbiae Humifusae 8 ~ 10 parts, Cortex Ailanthi 7 ~ 10 parts, Cortex Fraxini 11 ~ 13 parts, Radix Ardisiae Crenatae 8 ~ 10 parts, Testa arachidis hypogaeae 6 ~ 10 parts, Caulis Aristolochiae Manshuriensis 6 ~ 8 parts, recombinant human epidermal growth factor 0.002 ~ 0.004 part.
3. the compositions of anti-acne according to claim 1, is characterized in that, is made up of the raw material of following weight portion: Semen Alpiniae Katsumadai 9 parts, Herba Euphorbiae Humifusae 9 parts, Cortex Ailanthi 8 parts, Cortex Fraxini 12 parts, Radix Ardisiae Crenatae 9 parts, Testa arachidis hypogaeae 8 parts, Caulis Aristolochiae Manshuriensis 7 parts, recombinant human epidermal growth factor 0.003 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510794735.0A CN105233258A (en) | 2015-11-18 | 2015-11-18 | Composition for removing acne |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510794735.0A CN105233258A (en) | 2015-11-18 | 2015-11-18 | Composition for removing acne |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105233258A true CN105233258A (en) | 2016-01-13 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510794735.0A Pending CN105233258A (en) | 2015-11-18 | 2015-11-18 | Composition for removing acne |
Country Status (1)
| Country | Link |
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| CN (1) | CN105233258A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107149579A (en) * | 2017-05-18 | 2017-09-12 | 广东芭薇生物科技股份有限公司 | A kind of creams for pressing down acne effect plant composition containing oil-control |
| EP3720462A4 (en) * | 2017-10-19 | 2021-12-22 | Yale University | INHIBITION OF THE ANDROGEN RECEPTOR BY EXTRACTS OF MEDICAL HERBS AND COMPOSITIONS THEREOF |
-
2015
- 2015-11-18 CN CN201510794735.0A patent/CN105233258A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107149579A (en) * | 2017-05-18 | 2017-09-12 | 广东芭薇生物科技股份有限公司 | A kind of creams for pressing down acne effect plant composition containing oil-control |
| CN107149579B (en) * | 2017-05-18 | 2021-04-20 | 广东芭薇生物科技股份有限公司 | Cream containing plant composition with oil control and acne inhibition effects |
| EP3720462A4 (en) * | 2017-10-19 | 2021-12-22 | Yale University | INHIBITION OF THE ANDROGEN RECEPTOR BY EXTRACTS OF MEDICAL HERBS AND COMPOSITIONS THEREOF |
| US11839639B2 (en) | 2017-10-19 | 2023-12-12 | Yale University | Inhibition of androgen receptor by extracts of medicinal herbs and compositions thereof |
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