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CN105232431A - Antibacterial gingival-protecting high-efficiency toothpaste with specific component of modified traditional Chinese herbal medicine and preparation method of antibacterial gingival-protecting high-efficiency toothpaste - Google Patents

Antibacterial gingival-protecting high-efficiency toothpaste with specific component of modified traditional Chinese herbal medicine and preparation method of antibacterial gingival-protecting high-efficiency toothpaste Download PDF

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CN105232431A
CN105232431A CN201510782047.2A CN201510782047A CN105232431A CN 105232431 A CN105232431 A CN 105232431A CN 201510782047 A CN201510782047 A CN 201510782047A CN 105232431 A CN105232431 A CN 105232431A
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antibacterial
toothpaste
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gingival
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鄢祺丹
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25Silicon; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/413Nanosized, i.e. having sizes below 100 nm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/77Perfumes having both deodorant and antibacterial properties

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
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  • Inorganic Chemistry (AREA)
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  • Botany (AREA)
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  • Cosmetics (AREA)

Abstract

The invention discloses antibacterial gingival-protecting high-efficiency toothpaste with a specific component of a modified traditional Chinese herbal medicine and a preparation method of the antibacterial gingival-protecting high-efficiency toothpaste. The antibacterial gingival-protecting high-efficiency toothpaste is prepared from raw materials such as carboxymethyl chitosan, activated nano kieselguhr powder, nano montmorillonite powder, nano hydrated silica powder, low-polyesterification beta-glucan, a natural fibroin emulsifier, coconut monoglycerides sodium sulfonate, caffeic acid, sodium phytate, thymol, eucalyptol, menthol, an antradiacomphora extract, anise, nano propolis, polyethylene glycol, a chondrus crispus extract, a traditional Chinese medicine extract consisting of sculellaria barbata, Japanese beauty-berry leaves, lucid ganoderma, sweet-scented osmanthus, fructus piperis longi, alchornea trewioides, wild chrysanthemum flower, leaves of shrubby baeckea and acanthopanax and molecular water and molecular polyhydric alcohols rich in mineral element. With the combination of nano propolis and the traditional Chinese medicine extracts, the smell of the traditional Chinese medicine extracts is effectively improved, and meanwhile due to nanocrystallization, the molecularity of the traditional Chinese medicine extracts is improved, and the bioactivity is also improved.

Description

A kind ofly add the antibacterial of modification Chinese herbal medicine characteristic composition and protect gum high-efficiency tooth paste and preparation method
Technical field
The invention belongs to tooth paste product field, specifically relate to a kind ofly add the antibacterial of modification Chinese herbal medicine characteristic composition and protect gum high-efficiency tooth paste and preparation method.
Background technology
Current toothpaste is of a great variety, medicated toothpaste adds certain medicine on the basis of ordinary toothpaste, by the effect of medicine, reduce dental plaque, thus play the effect of anti-dental caries and periodontal disease, at present, medicated toothpaste pole is by the favor of people, and utilize toothpaste to promote the medicine with prevention effects and therapeutic efficiency to be a kind of comparatively ideal mode, but medicated toothpaste also has unfavorable aspect, first, toothpaste can not be refuted the long time and namely be gargled in mouth, medicine is made to be difficult to play drug effect at short notice, and special medicament dosage also must be avoided stimulating soft tissue in mouth, thus enough valid density can not be brought up to, the effect of toothpaste itself often hinder by dirt in mouth or limit by morphological characteristic, thus the region arriving real morbidity is difficult to, secondly the medicine in toothpaste, because standing time longer two, other chemical change occurred, lose original drug effect, active drug again Chang Yin is unsuitable for abnormal flavour and puts into toothpaste.Medicated toothpaste is a kind of imagination well, but the effect that really will reach prevention oral pathology needs to do some deep researchs.
Summary of the invention
For solving the problems of the technologies described above, the invention provides and a kind ofly add the antibacterial of modification Chinese herbal medicine characteristic composition and protect gum high-efficiency tooth paste and preparation method.
For achieving the above object, the technical solution used in the present invention is:
A kind ofly add the antibacterial of modification Chinese herbal medicine characteristic composition and protect gum high-efficiency tooth paste, comprise by the raw material of following weight portion: carboxymethyl chitosan 5-7, activation nano diatomite powder 15-20, nanoscale montmorillonite powder 35-45, nano hydrated Cab-O-sil 10-12, oligomeric esterification beta glucan 0.3-0.4, native silk protein emulsifying agent 0.2-0.3, Cortex cocois radicis monoglyceride sodium sulfonate 0.1-0.2, caffeic acid 1-2, sodium phytate 0.2-0.4, thymol 0.3-0.5, eucalyptol 0.2-0.3, menthol 1-1.2, Antrodia camphorata extract 0.9-1, anistree plain 1-2, nanometer propolis 2-3, Polyethylene Glycol 2-3, Zou Bo chondrus extract 0.9-1.3, by Herba Scutellariae Barbatae, Folium Callicarpae Formosanae, Ganoderma, Flos Osmanthi Fragrantis, Fructus Piperis Longi, Radix seu Folium Alchorneae trewioidis, Flos Chrysanthemi Indici, Folium Baeckeae, the Chinese medicine extract 3-4 of Radix Et Caulis Acanthopanacis Senticosi composition, be rich in the micromolecular water of mineral element in right amount, appropriate small molecule polyol.
Add an antibacterial preparation method of protecting gum high-efficiency tooth paste for modification Chinese herbal medicine characteristic composition, comprise the following steps:
(1) get be made up of Herba Scutellariae Barbatae, Folium Callicarpae Formosanae, Ganoderma, Flos Osmanthi Fragrantis, Fructus Piperis Longi, Radix seu Folium Alchorneae trewioidis, Flos Chrysanthemi Indici, Folium Baeckeae, Radix Et Caulis Acanthopanacis Senticosi Chinese medicine extract, nanometer propolis mixing, and the micromolecular water being rich in mineral element adding gross weight 3-4 times stirs, put into nanometer generator nanometered disposal 2-3h afterwards, obtain nanometer propolis modification Chinese herbal medicine extract micromolecule for subsequent use;
(2) by nanometer propolis modification Chinese herbal medicine extract micromolecule, anistree element, carboxymethyl chitosan, the mixing of activation nano diatomite powder, and add the gross weight 1.5-2.5 micromolecular water being rich in mineral element doubly, adopt high pressure homogenizer homogenizing process 1-1.6h afterwards, adopt spray drying technology dry the modification medicinal herb components of increase shelf-life of physical absorption solidification is for subsequent use;
(3) by nanoscale montmorillonite powder, the mixing of nano hydrated Cab-O-sil, gross weight 1-1.2 small molecule polyol is doubly added, after stirring, heated and stirred 2-4h at 200 DEG C, cooling ball milling, crosses 100 orders, obtains activated substrate composite powder for subsequent use;
(4) by caffeic acid, sodium phytate, thymol, eucalyptol, menthol, the mixing of Antrodia camphorata extract, and add the gross weight 2-3 micromolecular water being rich in mineral element doubly, after stirring, obtain complex liquid for subsequent use;
(5) by activated substrate composite powder, the modification medicinal herb components of the increase shelf-life of physical absorption solidification, the blender of band magnetic stirring apparatus is put in Polyethylene Glycol mixing, and add the gross weight 3-4 micromolecular water being rich in mineral element doubly, open magnetic stirring apparatus high-speed stirred 40-50min, add complex liquid afterwards, and continue slowly to be stirred to evenly, adding oligomeric esterification beta glucan afterwards, native silk protein emulsifying agent, Cortex cocois radicis monoglyceride sodium sulfonate, magnetic stirring apparatus is first adopted to strengthen magnetic force rapid stirring 1-2h, slowly adding Zou Bo chondrus extract, and continue stirring until evenly, high pressure is finally adopted to assist degassed process 4-5h to form uniform and stable body of paste, adopt Sterile vacuum tinning technology, tinning seals and get final product.
Beneficial effect of the present invention:
The present invention adopts nanometer propolis in conjunction with Chinese herbal medicine extract, effectively improve the taste of Chinese herbal medicine extract, pass through nanorize simultaneously, improve the micromolecule of Chinese herbal medicine extracting, improve biological activity, simultaneously in order to improve its bioactive stability, adopt the carboxymethyl chitosan of porous high absorption property, activation nano diatomite powder carries out absorption to it and stablizes, finally be added in toothpaste matrix, improve effect and the time expand of medicinal herb components, the carboxymethyl chitosan adopted, activation nano diatomite powder not only has adsorption, also has the antibacterial effect with serving as friction matrix, comprehensively overcome defect and the deficiency of Chinese herbal toothpaste, improve effect of Chinese herbal toothpaste.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme of the present invention is further described.
Embodiment 1:
A kind ofly add the antibacterial of modification Chinese herbal medicine characteristic composition and protect gum high-efficiency tooth paste, comprise by the raw material of following weight (kg): carboxymethyl chitosan 5, activation nano diatomite powder 15, nanoscale montmorillonite powder 45, nano hydrated Cab-O-sil 12, oligomeric esterification beta glucan 0.35, native silk protein emulsifying agent 0.25, Cortex cocois radicis monoglyceride sodium sulfonate 0.15, caffeic acid 1, sodium phytate 0.2, thymol 0.3, eucalyptol 0.2, menthol 1, Antrodia camphorata extract 0.9, anistree element 1, nanometer propolis 2, Polyethylene Glycol 2, Zou Bo chondrus extract 1.1, by Herba Scutellariae Barbatae, Folium Callicarpae Formosanae, Ganoderma, Flos Osmanthi Fragrantis, Fructus Piperis Longi, Radix seu Folium Alchorneae trewioidis, Flos Chrysanthemi Indici, Folium Baeckeae, the Chinese medicine extract 3 of Radix Et Caulis Acanthopanacis Senticosi composition, be rich in the micromolecular water of mineral element in right amount, appropriate small molecule polyol.
Add an antibacterial preparation method of protecting gum high-efficiency tooth paste for modification Chinese herbal medicine characteristic composition, comprise the following steps:
(1) get be made up of Herba Scutellariae Barbatae, Folium Callicarpae Formosanae, Ganoderma, Flos Osmanthi Fragrantis, Fructus Piperis Longi, Radix seu Folium Alchorneae trewioidis, Flos Chrysanthemi Indici, Folium Baeckeae, Radix Et Caulis Acanthopanacis Senticosi Chinese medicine extract, nanometer propolis mixing, and the micromolecular water being rich in mineral element adding gross weight 3-4 times stirs, put into nanometer generator nanometered disposal 2.5h afterwards, obtain nanometer propolis modification Chinese herbal medicine extract micromolecule for subsequent use;
(2) by nanometer propolis modification Chinese herbal medicine extract micromolecule, anistree element, carboxymethyl chitosan, the mixing of activation nano diatomite powder, and add the micromolecular water being rich in mineral element of gross weight 2 times, adopt high pressure homogenizer homogenizing process 1.3h afterwards, adopt spray drying technology dry the modification medicinal herb components of increase shelf-life of physical absorption solidification is for subsequent use;
(3) by nanoscale montmorillonite powder, the mixing of nano hydrated Cab-O-sil, the small molecule polyol of gross weight 1.1 times is added, after stirring, heated and stirred 3h at 200 DEG C, cooling ball milling, crosses 100 orders, obtains activated substrate composite powder for subsequent use;
(4) by caffeic acid, sodium phytate, thymol, eucalyptol, menthol, the mixing of Antrodia camphorata extract, and add the micromolecular water being rich in mineral element of gross weight 2.5 times, after stirring, obtain complex liquid for subsequent use;
(5) by activated substrate composite powder, the modification medicinal herb components of the increase shelf-life of physical absorption solidification, the blender of band magnetic stirring apparatus is put in Polyethylene Glycol mixing, and add the micromolecular water being rich in mineral element of gross weight 3.5 times, open magnetic stirring apparatus high-speed stirred 45min, add complex liquid afterwards, and continue slowly to be stirred to evenly, adding oligomeric esterification beta glucan afterwards, native silk protein emulsifying agent, Cortex cocois radicis monoglyceride sodium sulfonate, magnetic stirring apparatus is first adopted to strengthen magnetic force rapid stirring 1.5h, slowly adding Zou Bo chondrus extract, and continue stirring until evenly, high pressure is finally adopted to assist degassed process 4.5h to form uniform and stable body of paste, adopt Sterile vacuum tinning technology, tinning seals and get final product.
Embodiment 2: a kind ofly add the antibacterial of modification Chinese herbal medicine characteristic composition and protect gum high-efficiency tooth paste, comprise by the raw material of following weight (kg): carboxymethyl chitosan 6, activation nano diatomite powder 17.5, nanoscale montmorillonite powder 40, nano hydrated Cab-O-sil 11, oligomeric esterification beta glucan 0.35, native silk protein emulsifying agent 0.25, Cortex cocois radicis monoglyceride sodium sulfonate 0.15, caffeic acid 1.5, sodium phytate 0.3, thymol 0.4, eucalyptol 0.25, menthol 1.1, Antrodia camphorata extract 0.95, anistree element 1.5, nanometer propolis 2.5, Polyethylene Glycol 2.5, Zou Bo chondrus extract 1.1, by Herba Scutellariae Barbatae, Folium Callicarpae Formosanae, Ganoderma, Flos Osmanthi Fragrantis, Fructus Piperis Longi, Radix seu Folium Alchorneae trewioidis, Flos Chrysanthemi Indici, Folium Baeckeae, the Chinese medicine extract 3.5 of Radix Et Caulis Acanthopanacis Senticosi composition, be rich in the micromolecular water of mineral element in right amount, appropriate small molecule polyol.
Add an antibacterial preparation method of protecting gum high-efficiency tooth paste for modification Chinese herbal medicine characteristic composition, comprise the following steps:
(1) get be made up of Herba Scutellariae Barbatae, Folium Callicarpae Formosanae, Ganoderma, Flos Osmanthi Fragrantis, Fructus Piperis Longi, Radix seu Folium Alchorneae trewioidis, Flos Chrysanthemi Indici, Folium Baeckeae, Radix Et Caulis Acanthopanacis Senticosi Chinese medicine extract, nanometer propolis mixing, and the micromolecular water being rich in mineral element adding gross weight 3-4 times stirs, put into nanometer generator nanometered disposal 2.5h afterwards, obtain nanometer propolis modification Chinese herbal medicine extract micromolecule for subsequent use;
(2) by nanometer propolis modification Chinese herbal medicine extract micromolecule, anistree element, carboxymethyl chitosan, the mixing of activation nano diatomite powder, and add the micromolecular water being rich in mineral element of gross weight 2 times, adopt high pressure homogenizer homogenizing process 1.3h afterwards, adopt spray drying technology dry the modification medicinal herb components of increase shelf-life of physical absorption solidification is for subsequent use;
(3) by nanoscale montmorillonite powder, the mixing of nano hydrated Cab-O-sil, the small molecule polyol of gross weight 1.1 times is added, after stirring, heated and stirred 3h at 200 DEG C, cooling ball milling, crosses 100 orders, obtains activated substrate composite powder for subsequent use;
(4) by caffeic acid, sodium phytate, thymol, eucalyptol, menthol, the mixing of Antrodia camphorata extract, and add the micromolecular water being rich in mineral element of gross weight 2.5 times, after stirring, obtain complex liquid for subsequent use;
(5) by activated substrate composite powder, the modification medicinal herb components of the increase shelf-life of physical absorption solidification, the blender of band magnetic stirring apparatus is put in Polyethylene Glycol mixing, and add the micromolecular water being rich in mineral element of gross weight 3.5 times, open magnetic stirring apparatus high-speed stirred 45min, add complex liquid afterwards, and continue slowly to be stirred to evenly, adding oligomeric esterification beta glucan afterwards, native silk protein emulsifying agent, Cortex cocois radicis monoglyceride sodium sulfonate, magnetic stirring apparatus is first adopted to strengthen magnetic force rapid stirring 1.5h, slowly adding Zou Bo chondrus extract, and continue stirring until evenly, high pressure is finally adopted to assist degassed process 4.5h to form uniform and stable body of paste, adopt Sterile vacuum tinning technology, tinning seals and get final product.
Embodiment 3:
A kind ofly add the antibacterial of modification Chinese herbal medicine characteristic composition and protect gum high-efficiency tooth paste, comprise by the raw material of following weight (kg): carboxymethyl chitosan 7, activation nano diatomite powder 20, nanoscale montmorillonite powder 35, nano hydrated Cab-O-sil 10, oligomeric esterification beta glucan 0.35, native silk protein emulsifying agent 0.25, Cortex cocois radicis monoglyceride sodium sulfonate 0.15, caffeic acid 2, sodium phytate 0.4, thymol 0.5, eucalyptol 0.3, menthol 1.2, Antrodia camphorata extract 1, anistree element 2, nanometer propolis 3, Polyethylene Glycol 3, Zou Bo chondrus extract 1.1, by Herba Scutellariae Barbatae, Folium Callicarpae Formosanae, Ganoderma, Flos Osmanthi Fragrantis, Fructus Piperis Longi, Radix seu Folium Alchorneae trewioidis, Flos Chrysanthemi Indici, Folium Baeckeae, the Chinese medicine extract 4 of Radix Et Caulis Acanthopanacis Senticosi composition, be rich in the micromolecular water of mineral element in right amount, appropriate small molecule polyol.
Add an antibacterial preparation method of protecting gum high-efficiency tooth paste for modification Chinese herbal medicine characteristic composition, comprise the following steps:
(1) get be made up of Herba Scutellariae Barbatae, Folium Callicarpae Formosanae, Ganoderma, Flos Osmanthi Fragrantis, Fructus Piperis Longi, Radix seu Folium Alchorneae trewioidis, Flos Chrysanthemi Indici, Folium Baeckeae, Radix Et Caulis Acanthopanacis Senticosi Chinese medicine extract, nanometer propolis mixing, and the micromolecular water being rich in mineral element adding gross weight 3-4 times stirs, put into nanometer generator nanometered disposal 2.5h afterwards, obtain nanometer propolis modification Chinese herbal medicine extract micromolecule for subsequent use;
(2) by nanometer propolis modification Chinese herbal medicine extract micromolecule, anistree element, carboxymethyl chitosan, the mixing of activation nano diatomite powder, and add the micromolecular water being rich in mineral element of gross weight 2 times, adopt high pressure homogenizer homogenizing process 1.3h afterwards, adopt spray drying technology dry the modification medicinal herb components of increase shelf-life of physical absorption solidification is for subsequent use;
(3) by nanoscale montmorillonite powder, the mixing of nano hydrated Cab-O-sil, the small molecule polyol of gross weight 1.1 times is added, after stirring, heated and stirred 3h at 200 DEG C, cooling ball milling, crosses 100 orders, obtains activated substrate composite powder for subsequent use;
(4) by caffeic acid, sodium phytate, thymol, eucalyptol, menthol, the mixing of Antrodia camphorata extract, and add the micromolecular water being rich in mineral element of gross weight 2.5 times, after stirring, obtain complex liquid for subsequent use;
(5) by activated substrate composite powder, the modification medicinal herb components of the increase shelf-life of physical absorption solidification, the blender of band magnetic stirring apparatus is put in Polyethylene Glycol mixing, and add the micromolecular water being rich in mineral element of gross weight 3.5 times, open magnetic stirring apparatus high-speed stirred 45min, add complex liquid afterwards, and continue slowly to be stirred to evenly, adding oligomeric esterification beta glucan afterwards, native silk protein emulsifying agent, Cortex cocois radicis monoglyceride sodium sulfonate, magnetic stirring apparatus is first adopted to strengthen magnetic force rapid stirring 1.5h, slowly adding Zou Bo chondrus extract, and continue stirring until evenly, high pressure is finally adopted to assist degassed process 4.5h to form uniform and stable body of paste, adopt Sterile vacuum tinning technology, tinning seals and get final product.

Claims (2)

1. one kind is added the antibacterial of modification Chinese herbal medicine characteristic composition and protects gum high-efficiency tooth paste, it is characterized in that, comprise by the raw material of following weight portion: carboxymethyl chitosan 5-7, activation nano diatomite powder 15-20, nanoscale montmorillonite powder 35-45, nano hydrated Cab-O-sil 10-12, oligomeric esterification beta glucan 0.3-0.4, native silk protein emulsifying agent 0.2-0.3, Cortex cocois radicis monoglyceride sodium sulfonate 0.1-0.2, caffeic acid 1-2, sodium phytate 0.2-0.4, thymol 0.3-0.5, eucalyptol 0.2-0.3, menthol 1-1.2, Antrodia camphorata extract 0.9-1, anistree plain 1-2, nanometer propolis 2-3, Polyethylene Glycol 2-3, Zou Bo chondrus extract 0.9-1.3, by Herba Scutellariae Barbatae, Folium Callicarpae Formosanae, Ganoderma, Flos Osmanthi Fragrantis, Fructus Piperis Longi, Radix seu Folium Alchorneae trewioidis, Flos Chrysanthemi Indici, Folium Baeckeae, the Chinese medicine extract 3-4 of Radix Et Caulis Acanthopanacis Senticosi composition, be rich in the micromolecular water of mineral element in right amount, appropriate small molecule polyol.
2. an antibacterial preparation method of protecting gum high-efficiency tooth paste of adding modification Chinese herbal medicine characteristic composition as claimed in claim 1, is characterized in that, comprise the following steps:
(1) get be made up of Herba Scutellariae Barbatae, Folium Callicarpae Formosanae, Ganoderma, Flos Osmanthi Fragrantis, Fructus Piperis Longi, Radix seu Folium Alchorneae trewioidis, Flos Chrysanthemi Indici, Folium Baeckeae, Radix Et Caulis Acanthopanacis Senticosi Chinese medicine extract, nanometer propolis mixing, and the micromolecular water being rich in mineral element adding gross weight 3-4 times stirs, put into nanometer generator nanometered disposal 2-3h afterwards, obtain nanometer propolis modification Chinese herbal medicine extract micromolecule for subsequent use;
(2) by nanometer propolis modification Chinese herbal medicine extract micromolecule, anistree element, carboxymethyl chitosan, the mixing of activation nano diatomite powder, and add the gross weight 1.5-2.5 micromolecular water being rich in mineral element doubly, adopt high pressure homogenizer homogenizing process 1-1.6h afterwards, adopt spray drying technology dry the modification medicinal herb components of increase shelf-life of physical absorption solidification is for subsequent use;
(3) by nanoscale montmorillonite powder, the mixing of nano hydrated Cab-O-sil, gross weight 1-1.2 small molecule polyol is doubly added, after stirring, heated and stirred 2-4h at 200 DEG C, cooling ball milling, crosses 100 orders, obtains activated substrate composite powder for subsequent use;
(4) by caffeic acid, sodium phytate, thymol, eucalyptol, menthol, the mixing of Antrodia camphorata extract, and add the gross weight 2-3 micromolecular water being rich in mineral element doubly, after stirring, obtain complex liquid for subsequent use;
(5) by activated substrate composite powder, the modification medicinal herb components of the increase shelf-life of physical absorption solidification, the blender of band magnetic stirring apparatus is put in Polyethylene Glycol mixing, and add the gross weight 3-4 micromolecular water being rich in mineral element doubly, open magnetic stirring apparatus high-speed stirred 40-50min, add complex liquid afterwards, and continue slowly to be stirred to evenly, adding oligomeric esterification beta glucan afterwards, native silk protein emulsifying agent, Cortex cocois radicis monoglyceride sodium sulfonate, magnetic stirring apparatus is first adopted to strengthen magnetic force rapid stirring 1-2h, slowly adding Zou Bo chondrus extract, and continue stirring until evenly, high pressure is finally adopted to assist degassed process 4-5h to form uniform and stable body of paste, adopt Sterile vacuum tinning technology, tinning seals and get final product.
CN201510782047.2A 2015-11-16 2015-11-16 Antibacterial gingival-protecting high-efficiency toothpaste with specific component of modified traditional Chinese herbal medicine and preparation method of antibacterial gingival-protecting high-efficiency toothpaste Pending CN105232431A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106265105A (en) * 2016-08-24 2017-01-04 华泽庆 A kind of toothpaste adding kieselguhr and extract from pine needles and preparation method thereof
CN107802506A (en) * 2017-10-11 2018-03-16 苏州市金茂日用化学品有限公司 A kind of toothpaste for removing abnormal flavor in oral cavity containing diatomite
CN108078875A (en) * 2018-02-27 2018-05-29 贵安新区瑞诚生物工程有限公司 The preparation method and its production system of a kind of small molecule Chinese medicine antibacterial toothpaste and skin care item
CN108371648A (en) * 2018-03-21 2018-08-07 桂林良物造日用品有限公司 One kind containing diatomaceous natural activity toothpaste and preparation method thereof
CN108703910A (en) * 2018-08-08 2018-10-26 东莞市白天鹅纸业有限公司 A paper towel containing emulsion and its manufacturing method
CN114404318A (en) * 2022-02-24 2022-04-29 浙江大学 A kind of toothpaste containing silk protein and preparation method thereof

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CN102342905A (en) * 2011-10-24 2012-02-08 上海浩美净水设备有限公司 Toothpaste
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CN1739483A (en) * 2005-09-13 2006-03-01 美晨集团股份有限公司 Antibiotic toothpaste and its making process
WO2012087327A2 (en) * 2010-12-23 2012-06-28 Colgate-Palmolive Company Polymer systems
CN102342905A (en) * 2011-10-24 2012-02-08 上海浩美净水设备有限公司 Toothpaste

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106265105A (en) * 2016-08-24 2017-01-04 华泽庆 A kind of toothpaste adding kieselguhr and extract from pine needles and preparation method thereof
CN107802506A (en) * 2017-10-11 2018-03-16 苏州市金茂日用化学品有限公司 A kind of toothpaste for removing abnormal flavor in oral cavity containing diatomite
CN108078875A (en) * 2018-02-27 2018-05-29 贵安新区瑞诚生物工程有限公司 The preparation method and its production system of a kind of small molecule Chinese medicine antibacterial toothpaste and skin care item
CN108371648A (en) * 2018-03-21 2018-08-07 桂林良物造日用品有限公司 One kind containing diatomaceous natural activity toothpaste and preparation method thereof
CN108703910A (en) * 2018-08-08 2018-10-26 东莞市白天鹅纸业有限公司 A paper towel containing emulsion and its manufacturing method
CN114404318A (en) * 2022-02-24 2022-04-29 浙江大学 A kind of toothpaste containing silk protein and preparation method thereof

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Application publication date: 20160113