CN105194587A - A traditional Chinese medicine oral liquid for treating kidney-yang deficiency and its preparation method - Google Patents

Abstract

The invention discloses a traditional Chinese medicine oral liquid for treating kidney-yang deficiency and a preparation method thereof, wherein the traditional Chinese medicine oral liquid is prepared from the following raw materials in parts by weight: 7-13 parts of red ginseng, 17-23 parts of cortex albiziae, 27-33 parts of Chinese yam, 37-43 parts of raw astragalus membranaceus, 12-18 parts of radix curcumae, 12-18 parts of morinda officinalis, 9-15 parts of oroxylum indicum, 12-18 parts of polygala tenuifolia, 17-23 parts of dogwood fruit, 4-10 parts of membrana Follicularis ovi, 12-18 parts of raspberry, 12-18 parts of bighead atractylodes rhizome, 12-18 parts of fructus alpiniae oxyphyllae, 5-11 parts of galangal and 4-10 parts of radix glycyrrhizae preparata. The traditional Chinese medicine composition has the effects of warming and recuperating kidney yang, nourishing kidney yin, tonifying qi and kidney, and tonifying kidney and arresting spontaneous emission, and is a safe and reliable traditional Chinese medicine composition without any toxic or side effect, high utilization rate of effective components and quick response.

Description

A traditional Chinese medicine oral liquid for treating kidney-yang deficiency and its preparation method

technical field

The invention relates to a traditional Chinese medicine oral liquid for treating kidney-yang deficiency, which belongs to the field of traditional Chinese medicines.

Background technique

Kidney yang deficiency is a term in traditional Chinese medicine. Due to the deficiency of kidney yang, dereliction of duty, and failure of qi transformation, a type of deficiency and cold syndrome is called kidney yang deficiency syndrome. , or long-term illness and damage to the kidneys, and excessive room work. Traditional Chinese medicine believes that the kidney governs water, and the kidney yang has a transpiration effect on the water. If the kidney yang is insufficient, the transpiration and gasification will be weak, and the urine will be clear and long. Therefore, pathological changes of the kidneys exist in the syndrome of kidney yang deficiency. Kidney deficiency is mostly caused by long-term accumulation of diseases. It is absolutely impossible to rush to seek success and use tonic medicines, or use kidney-invigorating and yang-strengthening medicines with unknown ingredients. Instead, it should be recuperated slowly. The typical symptoms of kidney yang deficiency are soreness of the waist and knees, intolerance to fatigue, frequent fatigue, cold limbs, love of heat and fear of cold, etc. Some people with deficiency of kidney yang may also experience erectile dysfunction, premature ejaculation, and slippery semen. Functionality issue. At present, the commonly used Western medicines for treating kidney-yang deficiency contain hormones, which often have different degrees of toxic and side effects on the kidney, liver and gastrointestinal tract, and treat the symptoms but not the root cause. This invention uses traditional Chinese medicine to treat kidney-yang deficiency and regulate human body functions. The effect is remarkable, safe and non-toxic. side effect.

Contents of the invention

Aiming at the deficiencies in the prior art, the object of the present invention is to provide a traditional Chinese medicine oral liquid for treating kidney yang deficiency, which has the effects of warming and tonifying kidney yang, nourishing kidney yin, nourishing qi and tonifying kidney, and tonifying kidney and strengthening essence.

The present invention is achieved through the following technical solutions:

A traditional Chinese medicine oral liquid for treating kidney-yang deficiency, which is made of the following raw materials in parts by weight: 7-13 parts of red ginseng, 17-23 parts of Albizia juniper, 27-33 parts of yam, 37-43 parts of raw astragalus, 12- 18 parts, 12-18 parts of Morinda officinalis, 9-15 parts of wood butterfly, 12-18 parts of polygala, 17-23 parts of cornus, 4-10 parts of phoenix clothes, 12-18 parts of raspberry, 12-18 parts of Atractylodes macrocephala 12-18 parts of Yizhiren, 5-11 parts of galangal, 4-10 parts of roasted licorice.

Preferably, the parts by weight of each raw material are: 10 parts of red ginseng, 20 parts of Albizia juniper, 30 parts of Chinese yam, 40 parts of raw astragalus, 15 parts of curcuma, 15 parts of Morinda officinalis, 12 parts of wood butterfly, 15 parts of polygala, cornus 20 parts of meat, 7 parts of phoenix clothes, 15 parts of raspberry, 15 parts of Atractylodes macrocephala, 15 parts of Yizhi kernel, 8 parts of galangal, and 7 parts of roasted licorice.

Pharmacological effects:

Red ginseng: nature, flavor and meridian distribution: sweet, slightly bitter, warm; returns to spleen, lung, heart meridian, function and indications: greatly tonifies vital energy, recovers veins and consolidates detoxification, nourishes qi and absorbs blood; is used for physical weakness and cold extremities Weak pulse, lack of energy to absorb blood, uterine bleeding; heart failure, cardiogenic shock.

Cortex Albiziae: sweet and flat in nature and flavor; it has the effects of relieving depression, harmonizing blood, calming the heart, and reducing carbuncle; it has the effect of treating restlessness, depression, insomnia, lung abscess, carbuncle, scrofula, and tendon fracture.

Chinese yam: nature, flavor and meridian distribution: sweet, flat; returns to spleen, lung, kidney meridian, function and indications: nourishing spleen and stomach, promoting body fluid and benefiting lung, tonifying kidney and astringent essence; used for deficiency of the spleen, lack of food, persistent diarrhea, asthma due to lung deficiency Cough, kidney deficiency, spermatorrhea, leucorrhea, frequent urination, deficiency heat and thirst; bran-fried yam nourishes the spleen and stomach; used for spleen deficiency, diarrhea, loose stool, and excessive leucorrhea.

Radix Astragali: Nature, flavor and meridian distribution: sweet, warm; returns to lung and spleen meridian, functions and indications: invigorating qi and consolidating the exterior, diuretic to relieve toxins, evacuating pus, astringing sores and promoting granulation; Efficacy of raw Astragalus: invigorating qi and consolidating the exterior, diuretic Relieves toxins, expels pus, suppresses sores and promotes granulation; used for qi deficiency and fatigue, lack of food, loose stools, depression of central qi, prolapse of the anus after a long time, blood in the stool and metrorrhagia, spontaneous sweating due to surface deficiency, edema due to qi deficiency, astragalus discs, carbuncles that are difficult to burst, long-term ulceration No restraint, blood deficiency, flaccidity and jaundice, internal heat and thirst; chronic nephritis, proteinuria, diabetes.

Turmeric: property, flavor and meridian distribution: pungent, bitter, cold; returns to liver, heart, lung meridian, function and indications: promoting qi and removing blood stasis, clearing away heart-fire and relieving stagnation, promoting gallbladder and reducing jaundice; used for amenorrhea dysmenorrhea, chest and abdomen distension and pain , tingling pain, fever, coma, epilepsy, jaundice, red urine.

Morinda officinalis: nature, flavor and meridian return: sweet, pungent, slightly warm; returns kidney, liver meridian, functions and indications: nourishing kidney yang, strengthening muscles and bones, dispelling rheumatism; Abdominal cold pain, rheumatic arthralgia, flaccidity of muscles and bones.

Wood Butterfly: Nature, flavor and meridians: bitter, sweet, cool; returns lung, liver, stomach meridian, function and indications: clears lung and relieves pharynx, soothes liver and stomach; used for lung-heat cough, sore throat, hoarseness, liver Stomach pain.

Polygala: nature, flavor and meridian distribution: bitter, pungent, warm; Guixin, kidney, lung meridian, functions and indications: calming the nerves and improving intelligence, eliminating phlegm, reducing swelling; used for insomnia, dreaminess, forgetfulness and palpitation caused by heart-kidney disharmony, Confusion, coughing up sputum, sore swelling and poison, breast swelling and pain.

Cornus: nature, flavor and meridian distribution: sour, astringent, slightly warm; returns to the liver and kidney meridians, functions and indications: nourishing the liver and kidney, astringent essence and detoxification; used for vertigo and tinnitus, sore waist and knees, impotence and nocturnal emission, enuresis and frequent urination, Metrorrhagia, profuse sweating and prostration; internal heat and thirst.

Fenghuangyi: Nature and flavor: sweet, light, neutral in nature, meridian distribution: spleen, stomach, lung meridian, function and indications: nourishing yin and clearing lung, suppressing sores, eliminating nebula, bone-setting; main cough and asthma, sore throat, aphonia, lymphatic Tuberculosis, intractable ulcers, blurred vision, dizziness in the head, traumatic fractures.

Raspberry: property, flavor and meridian distribution: sweet, sour, warm; returns to kidney and bladder meridians, functions and indications: nourishing kidney, strengthening essence, reducing urination; used for enuresis due to kidney deficiency, frequent urination, impotence and premature ejaculation, spermatorrhea and spermatorrhea.

Atractylodes macrocephala: nature, flavor and meridian distribution: bitter, sweet, warm; returns to spleen and stomach meridians, functions and indications: invigorating the spleen and replenishing qi, drying dampness and promoting diuresis, antiperspirant, preventing miscarriage; used for insufficiency of the spleen, lack of food, abdominal distension and diarrhea, phlegm Drinking dizziness and palpitations, edema, spontaneous sweating, fetal movement; Tu Baizhu invigorates the spleen, harmonizes the stomach, and relieves miscarriage; used for deficiency of the spleen, lack of food, loose stools, and fetal movement.

Yizhiren: nature, flavor and meridian distribution: pungent, warm; return to the spleen and kidney meridians, functions and indications: warming the spleen to stop diarrhea, taking in saliva, warming the kidney, consolidating essence and reducing urination; used for spleen-cold diarrhea, abdominal Cold pain, excessive salivation, enuresis due to kidney deficiency, frequent urination, white turbid spermatorrhea.

Galangal: property, flavor and meridian distribution: pungent, hot; returns to the spleen and stomach meridians, functions and indications: warming the stomach and dispelling cold, eliminating food and relieving pain; used for abdominal cold pain, stomach cold and vomiting, belching and acid regurgitation.

Roasted Glycyrrhizae: meridians of nature and flavor: sweet, flat; Guixin, lung, spleen, stomach meridians; functions and indications: invigorating the spleen and stomach, replenishing qi and rejuvenating the veins; To detoxify aconite, Zhigancao Decoction has the therapeutic effects of nourishing qi, nourishing yin, unblocking yang and restoring pulse.

Another technical problem to be solved by the present invention is to provide a preparation method for the above-mentioned traditional Chinese medicine oral liquid.

Another technical problem to be solved by the present invention is achieved through the following technical solutions:

A preparation method of a traditional Chinese medicine oral liquid for treating kidney-yang deficiency, which is prepared by the following method:

(1) Take raw materials such as red ginseng, yam, cornus, and raspberry, wash them, dry them, crush them with a grinder while they are hot, pass them through a 30-50 mesh sieve, and set aside;

(2) Take the raw materials of Albizia Julibrissin, Raw Astragalus, Turmeric, Morinda officinalis, Wood Butterfly, Polygala, Phoenix Cloth, Atractylodes Rhizoma Atractylodes Rhizome, Yizhi Kernel, Galangal, Radix Glycyrrhizae, wash and dry, and use the dried raw materials while they are hot Pulverize with a pulverizer, pass through a 30-50 mesh sieve, and set aside;

(3) Add the crushed red ginseng, yam, cornus, and raspberry in the step (1) to the weight of the above raw materials and 8-13 times the water, decoct for 2-3 hours, and release the medicinal liquid; Add the weight of the above raw materials and 6-12 times the weight of water to decoct After 2-3 hours, the medicinal liquid is released; after the two medicinal residues are combined, add water 6-8 times its weight and decoct for 1-2 hours, and the medicinal liquid is released; the medicinal liquid decocted three times is combined, filtered, and the medicinal residues are discarded to obtain Filtrate, spare;

(4) Add the filtrate obtained in step (3) to 95% ethanol that is 1.5-2 times the weight of the filtrate, stir evenly and let it stand for 20-24 hours, precipitate, recover the ethanol, then filter through a centrifugal filter, collect the filtrate, and send the filtrate to Filtrate in a plate filter, the filter membrane pore size range of the plate filter is 0.8-2 μm, the pressure range is 0.15-0.3MPa during the filtration process, and the water flow rate on the membrane surface is 0.8-1.5T/h to obtain the filtrate ,spare;

(5) Send the filtrate obtained in step (4) into a plate filter for filtration. The filter membrane pore size range of the plate filter is 0.6-0.8 μm, and the pressure range is 0.15-0.3 MPa during the filtration process. The surface water flow rate is 0.8-1.5T/h, and the filtrate is obtained for use;

(6) Send the filtrate obtained in step (5) into a traditional Chinese medicine concentrator, and concentrate it under reduced pressure in the concentrator to a clear ointment with a relative density of 1.01-1.05 at 50-60°C to obtain a clear ointment for later use;

(7) Put the clear paste obtained in step (6) at 5-6°C for 24-36 hours, adjust the pH value to 6.0-8.0 with sodium hydroxide solution, filter, and seal the filtrate in a bottle. Sterilize with ultraviolet rays, and sterilize and irradiate for 20-30 minutes with ultraviolet wavelengths of 240nm-270nm, and pack to obtain a finished product, which is a traditional Chinese medicine oral liquid for treating kidney-yang deficiency.

Preferably, a preparation method of a traditional Chinese medicine oral liquid for treating kidney-yang deficiency is prepared by the following method:

(1) Take raw materials such as red ginseng, Chinese yam, cornus, and raspberry, wash them, dry them, pulverize them while they are hot, pass them through a 30-mesh sieve, and set aside;

(2) Take the raw materials of Albizia Julibrissin, Raw Astragalus, Turmeric, Morinda officinalis, Wood Butterfly, Polygala, Phoenix Cloth, Atractylodes Rhizoma Atractylodes Rhizome, Yizhi Kernel, Galangal, Radix Glycyrrhizae, wash and dry, and use the dried raw materials while they are hot Pulverize with a pulverizer, pass through a 30-mesh sieve, and set aside;

(3) Add the crushed red ginseng, yam, cornus, and raspberry in step (1) to the weight of the above raw materials and 13 times the water, decoct for 2 hours, and release the liquid medicine; after crushing in step (2), Acacia bark, raw astragalus, turmeric, Morinda officinalis, wood butterfly, polygala, phoenix clothes, Atractylodes macrocephala, yizhiren, galangal, and roasted licorice were added to the weight of the above materials and 12 times the water and decocted for 2 hours to release the liquid medicine After the two medicinal residues are combined, add 8 times the weight of the water and decoct for 1 hour to release the medicinal liquid; combine the medicinal liquid decocted three times, filter, discard the medicinal residues, and obtain the filtrate for subsequent use;

(4) Add the filtrate obtained in step (3) to 95% ethanol that is 1.5 times the weight of the filtrate, stir evenly and let it stand for 24 hours, precipitate, recover ethanol, filter through a centrifugal filter, collect the filtrate, and then send the filtrate to a plate filter Filtrate in, the filter membrane pore diameter of described plate filter is 0.8 μ m, the pressure range is 0.15MPa in the process of filtration, the membrane surface water flow rate is 1.5T/h, obtain filtrate, standby;

(5) Send the filtrate obtained in step (4) into a plate filter for filtration. The filter membrane pore size of the plate filter is 0.8 μm, the pressure range during the filtration is 0.15 MPa, and the water flow rate on the membrane surface is 0.8 T/h, the filtrate was obtained for subsequent use;

(6) Send the filtrate obtained in step (5) into a traditional Chinese medicine concentrator, and concentrate it under reduced pressure in the concentrator to a clear paste with a relative density of 1.05 at 60°C to obtain a clear paste for later use;

(7) Let the clear paste obtained in step (6) stand at 6°C for 24 hours, adjust the pH value to 6.0 with sodium hydroxide solution, filter, fill the filtrate into a bottle, sterilize with ultraviolet light, and Sterilize and irradiate with a wavelength of 254nm for 30 minutes, and pack to obtain a finished product, which is a traditional Chinese medicine oral liquid for treating kidney-yang deficiency.

Beneficial effects: the invention has the effects of warming and tonifying kidney yang, nourishing kidney yin, nourishing qi and tonifying kidney, tonifying kidney and consolidating essence, and is a safe and reliable traditional Chinese medicine composition without any toxic and side effects, high utilization rate of active ingredients and quick effect.

The present invention adopts pure traditional Chinese medicine as raw material, and according to the pathogenesis and clinical characteristics of kidney-yang deficiency, the prescription is prepared under the guidance of the theory of traditional Chinese medicine on the basis of not the activity of raw materials. It has definite curative effect and is an ideal drug for the treatment of patients with kidney yang deficiency.

Typical cases

Case 1: Ms. Cai, 30 years old, medical history: general fatigue and weakness, poor sleep at night, sore waist and knees, nocturia 5-6 times, hoarseness, diagnosed as kidney yang deficiency, taking the medicine of the present invention for 10 days, the patient after treatment Nocturia does not have, and sleep is normal, and patient work and study is not tired after taking medicine of the present invention 10 days, energetic.

Case 2: Ms. Wu, 55 years old, medical history: weakness of limbs, soreness of the waist and knees, fear of cold, fatigue, tinnitus, dizziness, arthralgia, diagnosed as deficiency of kidney yang, taking the medicine of the present invention for 10 days, the patient after treatment Subjective symptom obviously reduces, and the patient's above-mentioned complete symptom disappears after taking medicine of the present invention 10 days again.

Case 3: Ms. Shan, 45 years old, medical history: general fatigue and weakness, poor sleep at night, sore waist and knees, aversion to cold and cold extremities, diagnosed as: kidney yang deficiency, taking the drug of the present invention for 10 days, the patient's subjective symptoms were significantly reduced after treatment , and then take the medicine of the present invention after 10 days and the patient's above-mentioned symptoms disappear.

Case 4: Mr. Quan, 45 years old, had dark complexion, weak limbs, sore waist and knees, aversion to cold, loss of libido, fatigue, tinnitus, dizziness, clear and long urination, joint pain, diagnosed as: kidney yang deficiency, After taking the present invention for a week, the symptoms and signs of kidney yang deficiency are all significantly improved, and after taking the medicine of the present invention for 10 days, the patient is no longer afraid of cold, dizziness and tinnitus disappear completely, and arthralgia disappears.

Case 5: Ms. Long, 47 years old, medical history: lack of energy, easy fatigue, cold limbs, heavy body, thin leucorrhea, delayed menstruation with less volume and dark color, hearing loss, memory loss, diagnosed as: kidney yang deficiency After taking the present invention for two weeks, the spirit tends to improve, and the extremities are no longer cold, and after taking the medicine of the present invention for 10 days, the symptoms and signs of deficiency of kidney yang disappear substantially.

Case 6: Mr. Qiu, 49 years old, medical history: the patient has been dizzy for more than a year, insomnia, dreaminess, lassitude and fatigue, frequent menstruation, accompanied by tinnitus, soreness of the waist and knees, diagnosed as: kidney yang deficiency, taking the medicine of the present invention Treat 10 days, the patient's subjective symptom obviously reduces after the treatment, takes medicine of the present invention again after 10 days, and patient's above-mentioned symptom disappears completely.

Case 7: Mr. Wu, male, 39 years old, medical history: The patient has often had eyelid edema, dark circles aggravated, pale complexion, decreased physical fitness, poor resistance, easy to catch cold, afraid of cold, insomnia, irritability, Hotness, loss of libido, difficulty concentrating, elevated blood pressure, yellowish turbid urine. Take the medicine of the present invention for 10 days, and the symptoms are improved, and the spirit is greatly boosted, full of energy, and after taking the medicine of the present invention for 10 days, the symptoms all disappear.

clinical information

General information: 60 patients with kidney yang deficiency, aged 36-74 years, including 32 females and 28 males.

Diagnostic criteria: fear of cold, cold hands and feet; lack of energy, sore waist and knees; dyspnea, shortness of breath, wheezing and phlegm; spontaneous sweating; lethargy, dreaminess; low back pain, joint pain; hearing loss; early morning diarrhea, or constipation; clear urine Long or incessant drainage, oliguria, frequent urination at night; body edema, especially below the waist; dry, broken, falling, gray hair; memory loss; lower limb edema; sexual dysfunction; lower abdomen traction testicular swelling pain, Or scrotum contraction, worse when it is cold, slow when it is hot, impotence, premature ejaculation; women with cold uterus, infertility, thin leucorrhea, less delayed menstruation, dark color, lumps or dysmenorrhea; it is easy to lead to early menopause; uterus, Ovaries and breasts are prone to fibroids, cysts, hyperplasia; white and fat tongue or tooth marks; prone to prostatitis, secret urinary system infection, gynecological diseases and other reproductive and secret urinary system diseases; prone to osteoporosis, cervical spondylosis, Lumbar spondylosis; puffiness.

Therapeutic method: take oral liquid of the present invention, every day 2 times, each 30ml, 10 days are a course of treatment.

Efficacy criteria: cured: the clinical symptoms and signs of kidney yang deficiency disappear or basically disappear; markedly effective: the clinical symptoms and signs of kidney yang deficiency are significantly improved; effective: the clinical symptoms and signs of kidney yang deficiency are improved; ineffective: kidney yang The clinical symptoms and signs of deficiency were not significantly improved or aggravated.

Treatment results: 60 cases of kidney-yang deficiency were treated with this prescription, among which 55 cases were clinically cured, 5 cases were effective, and 0 cases were ineffective. The total effective rate was 100%.

Detailed ways

Example 1

The present invention treats the preparation of traditional Chinese medicine oral liquid for treating kidney-yang deficiency, and the parts by weight of each raw material are: 13 parts of red ginseng, 23 parts of Albizia Julibrissin, 33 parts of yam, 43 parts of raw astragalus, 18 parts of turmeric, 18 parts of Morinda officinalis, 15 parts of butterfly, 18 parts of polygala, 23 parts of cornus, 10 parts of phoenix clothes, 18 parts of raspberry, 18 parts of Atractylodes macrocephala, 18 parts of Yizhi kernel, 11 parts of galangal, 10 parts of roasted licorice;

Prepared by:

(1) Take raw materials such as red ginseng, yam, cornus, and raspberry, wash them, dry them, crush them with a grinder while they are hot, pass them through a 30-50 mesh sieve, and set aside;

(2) Take the raw materials of Albizia Julibrissin, Raw Astragalus, Turmeric, Morinda officinalis, Wood Butterfly, Polygala, Phoenix Cloth, Atractylodes Rhizoma Atractylodes Rhizome, Yizhi Kernel, Galangal, Radix Glycyrrhizae, wash and dry, and use the dried raw materials while they are hot Pulverize with a pulverizer, pass through a 30-50 mesh sieve, and set aside;

(3) Add the crushed red ginseng, yam, cornus, and raspberry in the step (1) to the weight of the above raw materials and 8-13 times the water, decoct for 2-3 hours, and release the medicinal liquid; Add the weight of the above raw materials and 6-12 times the weight of water to decoct After 2-3 hours, the medicinal liquid is released; after the two medicinal residues are combined, add water 6-8 times its weight and decoct for 1-2 hours, and the medicinal liquid is released; the medicinal liquid decocted three times is combined, filtered, and the medicinal residues are discarded to obtain Filtrate, spare;

(4) Add the filtrate obtained in step (3) to 95% ethanol that is 1.5-2 times the weight of the filtrate, stir evenly and let it stand for 20-24 hours, precipitate, recover the ethanol, then filter through a centrifugal filter, collect the filtrate, and send the filtrate to Filtrate in a plate filter, the filter membrane pore size range of the plate filter is 0.8-2 μm, the pressure range is 0.15-0.3MPa during the filtration process, and the water flow rate on the membrane surface is 0.8-1.5T/h to obtain the filtrate ,spare;

(5) Send the filtrate obtained in step (4) into a plate filter for filtration. The filter membrane pore size range of the plate filter is 0.6-0.8 μm, and the pressure range is 0.15-0.3 MPa during the filtration process. The surface water flow rate is 0.8-1.5T/h, and the filtrate is obtained for use;

(6) Send the filtrate obtained in step (5) into a traditional Chinese medicine concentrator, and concentrate it under reduced pressure in the concentrator to a clear ointment with a relative density of 1.01-1.05 at 50-60°C to obtain a clear ointment for later use;

(7) Put the clear paste obtained in step (6) at 5-6°C for 24-36 hours, adjust the pH value to 6.0-8.0 with sodium hydroxide solution, filter, and seal the filtrate in a bottle. Sterilize with ultraviolet rays, and sterilize and irradiate for 20-30 minutes with ultraviolet wavelengths of 240nm-270nm, and pack to obtain a finished product, which is a traditional Chinese medicine oral liquid for treating kidney-yang deficiency.

Usage: Take orally, 2 times a day, 30ml each time.

Example 2

The preparation of the traditional Chinese medicine oral liquid for treating kidney-yang deficiency of the present invention, the parts by weight of each raw material are: 10 parts of red ginseng, 20 parts of Albiziae barbass, 30 parts of yam, 40 parts of raw astragalus, 15 parts of turmeric, 15 parts of Morinda officinalis, 12 parts of butterfly, 15 parts of polygala, 20 parts of cornus, 7 parts of phoenix clothes, 15 parts of raspberry, 15 parts of Atractylodes macrocephala, 15 parts of Yizhi kernel, 8 parts of galangal, 7 parts of roasted licorice;

Prepared by:

(1) Take raw materials such as red ginseng, yam, cornus, and raspberry, wash them, dry them, crush them with a grinder while they are hot, pass them through a 30-50 mesh sieve, and set aside;

(2) Take the raw materials of Albizia Julibrissin, Raw Astragalus, Turmeric, Morinda officinalis, Wood Butterfly, Polygala, Phoenix Cloth, Atractylodes Rhizoma Atractylodes Rhizome, Yizhi Kernel, Galangal, Radix Glycyrrhizae, wash and dry, and use the dried raw materials while they are hot Pulverize with a pulverizer, pass through a 30-50 mesh sieve, and set aside;

(3) Add the crushed red ginseng, yam, cornus, and raspberry in the step (1) to the weight of the above raw materials and 8-13 times the water, decoct for 2-3 hours, and release the medicinal liquid; Add the weight of the above raw materials and 6-12 times the weight of water to decoct After 2-3 hours, the medicinal liquid is released; after the two medicinal residues are combined, add water 6-8 times its weight and decoct for 1-2 hours, and the medicinal liquid is released; the medicinal liquid decocted three times is combined, filtered, and the medicinal residues are discarded to obtain Filtrate, spare;

(4) Add the filtrate obtained in step (3) to 95% ethanol that is 1.5-2 times the weight of the filtrate, stir evenly and let it stand for 20-24 hours, precipitate, recover the ethanol, then filter through a centrifugal filter, collect the filtrate, and send the filtrate to Filtrate in a plate filter, the filter membrane pore size range of the plate filter is 0.8-2 μm, the pressure range is 0.15-0.3MPa during the filtration process, and the water flow rate on the membrane surface is 0.8-1.5T/h to obtain the filtrate ,spare;

(5) Send the filtrate obtained in step (4) into a plate filter for filtration. The filter membrane pore size range of the plate filter is 0.6-0.8 μm, and the pressure range is 0.15-0.3 MPa during the filtration process. The surface water flow rate is 0.8-1.5T/h, and the filtrate is obtained for use;

(6) Send the filtrate obtained in step (5) into a traditional Chinese medicine concentrator, and concentrate it under reduced pressure in the concentrator to a clear ointment with a relative density of 1.01-1.05 at 50-60°C to obtain a clear ointment for later use;

(7) Put the clear paste obtained in step (6) at 5-6°C for 24-36 hours, adjust the pH value to 6.0-8.0 with sodium hydroxide solution, filter, and seal the filtrate in a bottle. Sterilize with ultraviolet rays, and sterilize and irradiate for 20-30 minutes with ultraviolet wavelengths of 240nm-270nm, and pack to obtain a finished product, which is a traditional Chinese medicine oral liquid for treating kidney-yang deficiency.

Usage: Take orally, 2 times a day, 30ml each time.

Example 3

The present invention treats the preparation of traditional Chinese medicine oral liquid for treating kidney-yang deficiency, and the parts by weight of each raw material are: 7 parts of red ginseng, 17 parts of Albizia juniper, 27 parts of yam, 37 parts of raw astragalus, 12 parts of turmeric, 12 parts of Morinda officinalis, 9 parts of butterfly, 12 parts of polygala, 17 parts of cornus, 4 parts of phoenix clothes, 12 parts of raspberry, 12 parts of Atractylodes macrocephala, 12 parts of Yizhi kernel, 5 parts of galangal, 4 parts of roasted licorice;

Prepared by:

(1) Take raw materials such as red ginseng, yam, cornus, and raspberry, wash them, dry them, crush them with a grinder while they are hot, pass them through a 30-50 mesh sieve, and set aside;

(2) Take the raw materials of Albizia Julibrissin, Raw Astragalus, Turmeric, Morinda officinalis, Wood Butterfly, Polygala, Phoenix Cloth, Atractylodes Rhizoma Atractylodes Rhizome, Yizhi Kernel, Galangal, Radix Glycyrrhizae, wash and dry, and use the dried raw materials while they are hot Pulverize with a pulverizer, pass through a 30-50 mesh sieve, and set aside;

(3) Add the crushed red ginseng, yam, cornus, and raspberry in the step (1) to the weight of the above raw materials and 8-13 times the water, decoct for 2-3 hours, and release the medicinal liquid; Add the weight of the above raw materials and 6-12 times the weight of water to decoct After 2-3 hours, the medicinal liquid is released; after the two medicinal residues are combined, add water 6-8 times its weight and decoct for 1-2 hours, and the medicinal liquid is released; the medicinal liquid decocted three times is combined, filtered, and the medicinal residues are discarded to obtain Filtrate, spare;

(4) Add the filtrate obtained in step (3) to 95% ethanol that is 1.5-2 times the weight of the filtrate, stir evenly and let it stand for 20-24 hours, precipitate, recover the ethanol, then filter through a centrifugal filter, collect the filtrate, and send the filtrate to Filtrate in a plate filter, the filter membrane pore size range of the plate filter is 0.8-2 μm, the pressure range is 0.15-0.3MPa during the filtration process, and the water flow rate on the membrane surface is 0.8-1.5T/h to obtain the filtrate ,spare;

(5) Send the filtrate obtained in step (4) into a plate filter for filtration. The filter membrane pore size range of the plate filter is 0.6-0.8 μm, and the pressure range is 0.15-0.3 MPa during the filtration process. The surface water flow rate is 0.8-1.5T/h, and the filtrate is obtained for use;

(6) Send the filtrate obtained in step (5) into a traditional Chinese medicine concentrator, and concentrate it under reduced pressure in the concentrator to a clear ointment with a relative density of 1.01-1.05 at 50-60°C to obtain a clear ointment for later use;

(7) Put the clear paste obtained in step (6) at 5-6°C for 24-36 hours, adjust the pH value to 6.0-8.0 with sodium hydroxide solution, filter, and seal the filtrate in a bottle. Sterilize with ultraviolet rays, and sterilize and irradiate for 20-30 minutes with ultraviolet wavelengths of 240nm-270nm, and pack to obtain a finished product, which is a traditional Chinese medicine oral liquid for treating kidney-yang deficiency.

Usage: Take orally, 2 times a day, 30ml each time.

Claims (6)

1. treat a Chinese medicine oral liquid for insufficiency of kidney-YANG, it is characterized in that: be made up of following raw material: Radix Ginseng Rubra 7-13 part, Cortex Albiziae 17-23 part, Rhizoma Dioscoreae 27-33 part, Radix Astragali 37-43 part, Radix Curcumae 12-18 part, Radix Morindae Officinalis 12-18 part, Semen Oroxyli 9-15 part, Radix Polygalae 12-18 part, Fructus Corni 17-23 part, Membrana Follicularis ovi 4-10 part, Fructus Rubi 12-18 part, Rhizoma Atractylodis Macrocephalae 12-18 part, Fructus Alpiniae Oxyphyllae 12-18 part, Rhizoma Alpiniae Officinarum 5-11 part, Radix Glycyrrhizae Preparata 4-10 part.

2. a kind of Chinese medicine oral liquid for the treatment of insufficiency of kidney-YANG according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Ginseng Rubra 10 parts, Cortex Albiziae 20 parts, Rhizoma Dioscoreae 30 parts, Radix Astragali 40 parts, Radix Curcumae 15 parts, Radix Morindae Officinalis 15 parts, Semen Oroxyli 12 parts, Radix Polygalae 15 parts, Fructus Corni 20 parts, Membrana Follicularis ovi 7 parts, Fructus Rubi 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Fructus Alpiniae Oxyphyllae 15 parts, Rhizoma Alpiniae Officinarum 8 parts, Radix Glycyrrhizae Preparata 7 parts.

3. a kind of Chinese medicine oral liquid for the treatment of insufficiency of kidney-YANG according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Ginseng Rubra 13 parts, Cortex Albiziae 23 parts, Rhizoma Dioscoreae 33 parts, Radix Astragali 43 parts, Radix Curcumae 18 parts, Radix Morindae Officinalis 18 parts, Semen Oroxyli 15 parts, Radix Polygalae 18 parts, Fructus Corni 23 parts, Membrana Follicularis ovi 10 parts, Fructus Rubi 18 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Fructus Alpiniae Oxyphyllae 18 parts, Rhizoma Alpiniae Officinarum 11 parts, Radix Glycyrrhizae Preparata 10 parts.

4. a kind of Chinese medicine oral liquid for the treatment of insufficiency of kidney-YANG according to claim 1, is characterized in that: the weight portion of each raw material is: Radix Ginseng Rubra 7 parts, Cortex Albiziae 17 parts, Rhizoma Dioscoreae 27 parts, Radix Astragali 37 parts, Radix Curcumae 12 parts, Radix Morindae Officinalis 12 parts, Semen Oroxyli 9 parts, Radix Polygalae 12 parts, Fructus Corni 17 parts, Membrana Follicularis ovi 4 parts, Fructus Rubi 12 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Fructus Alpiniae Oxyphyllae 12 parts, Rhizoma Alpiniae Officinarum 5 parts, Radix Glycyrrhizae Preparata 4 parts.

5. a kind of preparation method for the treatment of the Chinese medicine oral liquid of insufficiency of kidney-YANG according to claim 1 and 2, is characterized in that: be prepared from by following methods:

(1) get raw material Radix Ginseng Rubra, Rhizoma Dioscoreae, Fructus Corni, Fructus Rubi cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;

(2) get raw material Cortex Albiziae, Radix Astragali, Radix Curcumae, Radix Morindae Officinalis, Semen Oroxyli, Radix Polygalae, Membrana Follicularis ovi, the Rhizoma Atractylodis Macrocephalae, Fructus Alpiniae Oxyphyllae, Rhizoma Alpiniae Officinarum, Radix Glycyrrhizae Preparata cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30-50 mesh sieve, for subsequent use;

(3) Radix Ginseng Rubra after pulverizing in step (1), Rhizoma Dioscoreae, Fructus Corni, Fructus Rubi are added above-mentioned raw materials weight and 8-13 water doubly, decoct 2-3 hour, release medicinal liquid; Cortex Albiziae after pulverizing in step (2), Radix Astragali, Radix Curcumae, Radix Morindae Officinalis, Semen Oroxyli, Radix Polygalae, Membrana Follicularis ovi, the Rhizoma Atractylodis Macrocephalae, Fructus Alpiniae Oxyphyllae, Rhizoma Alpiniae Officinarum, Radix Glycyrrhizae Preparata are added above-mentioned raw materials weight and 6-12 soak by water 2-3 hour doubly, releases medicinal liquid; Add its weight 6-8 soak by water 1-2 hour doubly after twice medicinal residues merges, release medicinal liquid; Merge the medicinal liquid decocted for three times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;

(4) gained filtrate in step (3) is added the ethanol of filtrate weight 1.5-2 times 95%, leave standstill 20-24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane pore diameter range of described leaf filter is 0.8-2 μm, in the process of filtering, pressure limit is 0.15-0.3MPa, face discharge is 0.8-1.5T/h, obtains filtrate, for subsequent use;

(5) filter in step (4) in gained filtrate feeding leaf filter, the filter membrane pore diameter range of described leaf filter is 0.6-0.8 μm, and in the process of filtering, pressure limit is 0.15-0.3MPa, and face discharge is 0.8-1.5T/h, obtain filtrate, for subsequent use;

(6) gained filtrate in step (5) is sent into traditional Chinese drug inspissation machine, in thickener, be evaporated to the clear paste of relative density 1.01-1.05 during 50-60 DEG C, obtain clear paste, for subsequent use;

(7) gained clear paste in step (6) is statically placed in 24-36 hour under the condition of 5-6 DEG C, by sodium hydroxide solution adjust ph to 6.0-8.0, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 20-30min is irradiated in ultraviolet wavelength 240nm-270nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid of insufficiency of kidney-YANG.

6. a kind of preparation method for the treatment of the Chinese medicine oral liquid of insufficiency of kidney-YANG according to claim 1 and 2, is characterized in that: be prepared from by following methods:

(1) get raw material Radix Ginseng Rubra, Rhizoma Dioscoreae, Fructus Corni, Fructus Rubi cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30 mesh sieves, for subsequent use;

(2) get raw material Cortex Albiziae, Radix Astragali, Radix Curcumae, Radix Morindae Officinalis, Semen Oroxyli, Radix Polygalae, Membrana Follicularis ovi, the Rhizoma Atractylodis Macrocephalae, Fructus Alpiniae Oxyphyllae, Rhizoma Alpiniae Officinarum, Radix Glycyrrhizae Preparata cleaning, dry, the raw material of drying is pulverized with pulverizer while hot, crosses 30 mesh sieves, for subsequent use;

(3) Radix Ginseng Rubra after pulverizing in step (1), Rhizoma Dioscoreae, Fructus Corni, Fructus Rubi are added the water of above-mentioned raw materials weight and 13 times, decocts 2 hours, releasing medicinal liquid; Cortex Albiziae after pulverizing in step (2), Radix Astragali, Radix Curcumae, Radix Morindae Officinalis, Semen Oroxyli, Radix Polygalae, Membrana Follicularis ovi, the Rhizoma Atractylodis Macrocephalae, Fructus Alpiniae Oxyphyllae, Rhizoma Alpiniae Officinarum, Radix Glycyrrhizae Preparata are added the soak by water 2 hours of above-mentioned raw materials weight and 12 times, release medicinal liquid; Twice medicinal residues add the soak by water 1 hour of its weight 8 times after merging, release medicinal liquid; Merge the medicinal liquid decocted for three times, filter, abandon medicinal residues, obtain filtrate, for subsequent use;

(4) gained filtrate in step (3) is added the ethanol of 95% of filtrate weight 1.5 times, leave standstill 24h after stirring, precipitation, reclaim ethanol, filtered by centrifugal filter again, collect filtrate, filtrate is sent in leaf filter and is filtered, and the filter membrane aperture of described leaf filter is 0.8 μm, in the process of filtering, pressure limit is 0.15MPa, face discharge is 1.5T/h, obtains filtrate, for subsequent use;

(5) filter in step (4) in gained filtrate feeding leaf filter, the filter membrane aperture of described leaf filter is 0.8 μm, and in the process of filtering, pressure limit is 0.15MPa, and face discharge is 0.8T/h, obtains filtrate, for subsequent use;

(6) gained filtrate in step (5) is sent into traditional Chinese drug inspissation machine, when being evaporated to 60 DEG C in thickener, the clear paste of relative density 1.05, obtains clear paste, for subsequent use;

(7) gained clear paste in step (6) is statically placed in 24 hours under the condition of 6 DEG C, by sodium hydroxide solution adjust ph to 6.0, filter, by in filtrate embedding bottle, with ultraviolet disinfection, 30min is irradiated in ultraviolet wavelength 254nm sterilizing, packs to obtain finished product, must treat the Chinese medicine oral liquid of insufficiency of kidney-YANG.