CN1051303A - Wearable hemodialysis filter device - Google Patents
Wearable hemodialysis filter device Download PDFInfo
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- CN1051303A CN1051303A CN 89108386 CN89108386A CN1051303A CN 1051303 A CN1051303 A CN 1051303A CN 89108386 CN89108386 CN 89108386 CN 89108386 A CN89108386 A CN 89108386A CN 1051303 A CN1051303 A CN 1051303A
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- Prior art keywords
- filter
- dialyser
- wearing device
- object wearing
- dialyzate bag
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- 238000001631 haemodialysis Methods 0.000 title claims description 16
- 230000000322 hemodialysis Effects 0.000 title claims description 16
- 238000000502 dialysis Methods 0.000 claims abstract description 25
- 238000001914 filtration Methods 0.000 claims abstract description 14
- 210000003462 vein Anatomy 0.000 claims abstract description 12
- 210000003734 kidney Anatomy 0.000 claims abstract description 11
- 210000001367 artery Anatomy 0.000 claims abstract description 6
- 239000003146 anticoagulant agent Substances 0.000 claims description 21
- 229940127219 anticoagulant drug Drugs 0.000 claims description 21
- 239000008280 blood Substances 0.000 claims description 20
- 210000004369 blood Anatomy 0.000 claims description 19
- 239000007788 liquid Substances 0.000 claims description 15
- 238000011282 treatment Methods 0.000 claims description 14
- 239000004677 Nylon Substances 0.000 claims description 12
- 229920001778 nylon Polymers 0.000 claims description 12
- 210000003017 ductus arteriosus Anatomy 0.000 claims description 11
- 210000003414 extremity Anatomy 0.000 claims description 10
- 230000017531 blood circulation Effects 0.000 claims description 6
- 238000010241 blood sampling Methods 0.000 claims description 6
- 210000000245 forearm Anatomy 0.000 claims description 4
- 206010016717 Fistula Diseases 0.000 claims description 3
- 230000003890 fistula Effects 0.000 claims description 3
- 239000004744 fabric Substances 0.000 claims description 2
- 239000002649 leather substitute Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 claims 4
- 239000004033 plastic Substances 0.000 claims 3
- 229920003023 plastic Polymers 0.000 claims 3
- 230000008321 arterial blood flow Effects 0.000 claims 2
- 239000012510 hollow fiber Substances 0.000 claims 1
- 239000010985 leather Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229920002379 silicone rubber Polymers 0.000 claims 1
- 239000004945 silicone rubber Substances 0.000 claims 1
- 208000034486 Multi-organ failure Diseases 0.000 abstract description 5
- 230000004087 circulation Effects 0.000 abstract description 4
- 208000009304 Acute Kidney Injury Diseases 0.000 abstract description 3
- 208000010718 Multiple Organ Failure Diseases 0.000 abstract description 3
- 208000033626 Renal failure acute Diseases 0.000 abstract description 3
- 201000011040 acute kidney failure Diseases 0.000 abstract description 3
- 208000012998 acute renal failure Diseases 0.000 abstract description 3
- 208000029744 multiple organ dysfunction syndrome Diseases 0.000 abstract description 3
- 206010070863 Toxicity to various agents Diseases 0.000 abstract description 2
- 208000020832 chronic kidney disease Diseases 0.000 abstract description 2
- 208000022831 chronic renal failure syndrome Diseases 0.000 abstract description 2
- 230000008359 toxicosis Effects 0.000 abstract 1
- 239000000385 dialysis solution Substances 0.000 description 16
- 238000002615 hemofiltration Methods 0.000 description 11
- 238000007485 conventional hemodialysis Methods 0.000 description 6
- 238000013461 design Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 208000001953 Hypotension Diseases 0.000 description 3
- 208000011580 syndromic disease Diseases 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 206010003226 Arteriovenous fistula Diseases 0.000 description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 238000011010 flushing procedure Methods 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 208000021822 hypotensive Diseases 0.000 description 2
- 230000001077 hypotensive effect Effects 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 238000007086 side reaction Methods 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 206010018833 Haematocoele Diseases 0.000 description 1
- 208000005873 Hematocele Diseases 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 231100000643 Substance intoxication Toxicity 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 201000004920 hematocele of tunica vaginalis testis Diseases 0.000 description 1
- 230000036543 hypotension Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- -1 webbing Substances 0.000 description 1
Images
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- External Artificial Organs (AREA)
Abstract
A medical wearable hemodiafiltration device (PLM type wearable artificial kidney) comprises a hemodiafiltration system and a wearable device for wearing the hemodiafiltration system on a body. It is mainly used for treating acute renal failure, chronic renal failure, multiple organ failure, toxicosis, drug poisoning, etc. Connecting the artery and vein catheters of the hemodiafiltration system with the artery and vein fistulae of the patient; connecting dialysate circulation pipes to two dialysate holes of the dialyzer or filter, respectively, connecting full dialysate bags and empty dialysate bags to the other ends of the dialysate circulation pipes, and repeatedly exchanging the two positions one above the other and one below the other to perform dialysis filtering; the system can be freely moved when being arranged on a wearing device.
Description
The present invention relates to a kind of armarium, particularly a kind of wearable hemodialysis filtration device or PLM type Wearable artificial kidney.Be suitable for treating acute renal failure, chronic kidney hypofunction, multiple organ failure, MOF, poisonous substance, drug intoxication etc.
At present, the shortcoming of conventional hemodialysis (CHD) machine (artificial kidney) has: (with Sweden GambroAK-10 type and U.S. SPS-550 type is example, and every is overlapped ten thousand yuans of 15-18) 1, costs an arm and a leg; 2, heaviness; 3, rely on the water source; 4, rely on power supply; 5, side reaction is big, and almost every example unbalanced syndrome all takes place makes the patient forbidding in the treatment.Continuous arterio venous hemofiltration (CAVH), though to rescuing the acute and chronic renal failure of cardiovascular instability, multiple organ failure, MOF patient offers convenience,, it is one of its shortcoming that CAVH removes rate variance to micromolecule; It two is need to replenish a large amount of displacement liquids in the treatment and easily cause infecting treatment cost height; Its three be the treatment in the patient stiff.Slowly continuous blood dialysis (SCHD) and arteriovenous hemodialysis (CAVHD) continuously, its shortcoming has: 1, dialysis solution still is one-way flow, and disposable application is relatively wasted; 2, the patient only can lie in bed and carries out the European patent of looking into, application number 861157337 in the treatment; IntCl
4A61M1/14.This " external method for treating liquids and system " though can be used for hemodialysis and hemofiltration, designs too complicated; Volume is big and heavy; The cost height.United States Patent (USP), the patent No. 4,547,186; IntCl
4A61M4/00.By " automatic blood transfusion system " of Bartlett invention, used vacuum pump, centrifugal force and atmospheric ultimate principle.Be used for attracting hematocele in the wound, add anticoagulant simultaneously, and then feed back to patient in operation.This system only can make blood and reclaim, and can not make hemodialysis and hemofiltration.United States Patent (USP), the patent No. 4,551,131; IntCl
3A61M1/00; A61M5/00.By " automatic blood transfusion and the anticoagulant delivery system " of inventions such as Miles, its design is almost completely the same with " automatic blood transfusion system " of Bartlett invention, can not make hemodialysis and hemofiltration.The invention of Miles also is to be used for operation autotransfusion, United States Patent (USP), the patent No. 4,316,466; IntCl
3A61M1/00.By " the body fluid drainage system " of Babb invention, this device design is complicated.Though wearablely do the body fluid drain, can not do hemodialysis and hemofiltration on one's body.Chinese patent, patent No. 87200686U; IntCl
4A61M1/14; A61M5/00, " the portable medical automatic control dialysis transfusion device " that designed by Liu Qingyuan only can be used to do peritoneal dialysis, can not carry out hemodialysis, hemofiltration, on one's body more can not being worn on.
Purpose of the present invention, a kind of wearable hemodialysis, filtering device or the Wearable artificial kidney that designs at above deficiency exactly.This device has greatly been simplified hemodialysis, and hemofiltration equipment reduces cost, is convenient to popularize, promote.This device can be dressed, can be free movable in the treatment, improved patients ' life quality.This device does not rely on the water source power supply, is not subjected to the influence of cutting off the water suddenly, having a power failure in the treatment.This device curative effect height reduces or eliminates side reaction (unbalanced syndrome).Simple to operate, be convenient to learning and mastering.This device is used for the treatment of the patient at ordinary times, can be used for rescuing the wounded wartime.
The present invention is achieved in that this device adopts hemodialyzer or filter (1), end blood manhole appendix at dialyser or filter (1), connect blood circulation ductus arteriosus (2), on going up with T joint, ductus arteriosus (2) appends anticoagulant conduit (3), connect anticoagulant syringe (4) on the anticoagulant conduit (3) appending, blood sampling specimen hole (5) is arranged on ductus arteriosus (2); Other end blood manhole appendix at dialyser or filter (1) connects blood circulation venous duct (6), blood sampling specimen hole (7) and dosing short tube (8).Side dialysate hole at dialyser or filter (1) connects dialysis liquid circulating tube (9), and the other end in (9) is connected with soft packed dialyzate bag (10); Another side dialysate hole at dialyser or filter (1) connects dialysis liquid circulating tube (11) and empty dialyzate bag (12).As shown in Figure 1.When through sterilization, flushing, emptying the dialyser or the filter (1) of gas and the anticoagulant of substituting the bad for the good in advance, ductus arteriosus (2) and venous duct (6) are with after human body artery, vein are connected respectively, blood promptly leans on the driving force of heart, from tremulous pulse → ductus arteriosus (2) → dialyser or filter (1) → venous duct (6) → vein, be back in the body, circulation repeatedly is without blood pump.As shown in Figure 2.When the dialyzate bag (10) of dialysis solution was filled in rising, dialysis solution promptly leaned on gravity, atmospheric pressure, through dialysis liquid circulating tube (9), flow into dialyser or filter (1), another dialysate hole from (1) flows out again, flow in the sky dialyzate bag (12) through dialysis liquid circulating tube (11); Treat that elevated dialyzate bag stream is empty, upset replaces repeatedly at once, regularly changes fresh dialysis solution, the liquid pump of need not dialysing.According to the state of an illness, the general per 30 minutes once fresh dialysis solution of replacing, each 2000ml.After the dialysis filtration treatment beginning, regularly from appending anticoagulant conduit (3) injection anticoagulant (4).As using dialyser or the filter that does not need anticoagulant, then without anticoagulant.Shown in figure two.When the forearm that the patient is had arteriovenous fistula is put in the limb protecting belt (20) of object wearing device, dialyser or filter (1) are placed in dialyser or the filter belt dressing (25), anticoagulant syringe (4) is placed syringe protecting belt (21), dialyzate bag (10) or (12) be will expire and the link or the pocket (15) of the object wearing device of patient's shoulder placed, the patient can be free movable, and aprowl carrying out the continuous hemodialysis filtering therapy.As shown in Figure 3.When inertia, desirable seat of patient or clinostatism.Full dialyzate bag (10) or (12) are hung over a high position, and empty dialyzate bag (12) or (10) place low level, replace repeatedly, regularly change.When changing dialysis solution, there is not dialysis solution to flow in dialyser or the filter (1), this moment is based on filtration; When dialysis solution circulates in dialyser or filter (1), divided by dialysis be main outside, because of the dialysis solution malleation less than arteriotony, the semipermeable membrane of blood flow this moment by dialyser or filter (1) has filtration equally.If empty dialyzate bag (12) or (10) are placed lower position, filtration is strengthened because of the suction function that the potential difference that falls forms.As Fig. 4.
The present invention can be achieved in that at ductus arteriosus (2) and locate to use blood pump (13) temporarily, hemodialysis, hemofiltration when being implemented in hypotensive patient and setting up vein → venous blood path.As shown in Figure 5.
The present invention can also be achieved in that object wearing device (26) is by synthetic leather, webbing, and nylon agraffe, becket, elastic fabric parcel elastic cord constitutes.The basic structure of object wearing device (26) is by object wearing device bottom (14), link or pocket (19), adjusting button (18), object wearing device pocket (15), limb protecting belt (20), syringe protecting belt (21), the air-vent (22) of the various patterns of limb protecting belt, different-diameter, dialyser or filter belt dressing (25) and limb protecting belt (20) are formed.The method that limb protecting belt (20) and hemodialyzer or filter belt dressing (25) one end stick with glue and sew up is fixed on the bottom (14) of object wearing device, the method that sticks with glue and sew up on another free-end inner edge is fixed with nylon agraffe positive pole (23) and (24), go up fixed nylon agraffe negative pole (16) and (17) joining mutually with corresponding object wearing device bottom (14) separately respectively, reach the fixedly purpose of upper limb forearm and dialyser or filter (1).Shown in Fig. 6-9.
Simple structure of the present invention, cost is low, can dress, and does not rely on water source, power supply, has eliminated the unbalanced syndrome that conventional hemodialysis (CHD) can cause, and is easy to operate, to micromolecule clearance rate height, need not replenish displacement liquid in the treatment, gross weight 2-3 kilogram.Be adapted at rescuing wartime the wounded.
Below in conjunction with accompanying drawing the present invention is described in further detail:
Fig. 1 is a principle schematic before hemodialysis of the present invention, the filtration system works;
1-hemodialyzer or transfusion filters among the figure, 2-arterial blood circulation conduit, 3-appends the anticoagulant conduit, 4-anticoagulant and syringe, the 5-specimen hole of taking a blood sample, 6-venous duct, the 7-specimen hole of taking a blood sample, 8-medicine-adding infusion short tube, the 9-dialysis liquid circulating tube, 10-dialyzate bag and dialysis solution, 11-dialysis liquid circulating tube, the empty dialyzate bag of 12-.
Fig. 2 is the present invention and operation principle sketch map after human body is connected;
Dialysis solution among the figure in the 10-dialyzate bag flow in the 12-dialyzate bag through the 11-dialysis liquid circulating tube after flowing through the 9-dialysis liquid circulating tube to dialyser or filter, going out dialyser or filter.
Fig. 3 is the operation principle sketch map of the present invention when being worn on one's body;
19-link or pocket among the figure, 21-syringe protecting belt, 20-limb protecting belt, 25-dialyser or filter belt dressing, 15-object wearing device pocket.
Fig. 4 is a kind of operation principle sketch map of the present invention when being worn on one's body;
Except that with object wearing device hemodialysis of the present invention, hemofiltration system being worn on one's body with Fig. 2 is different, other is with shown in Figure 2 the same shown in the figure.
Fig. 5 is a principle schematic before the another kind of work of hemodialysis of the present invention, hemofiltration system;
13-blood pump among the figure, other and Fig. 1 are just the same, the patient that operation principle shown in Figure 5 is mainly used in companion's hypotension or sets up vein → venous blood path.
Fig. 6 is an object wearing device integral body of the present invention.
Fig. 7 is an object wearing device bottom of the present invention; 19-object wearing device link or pocket among the figure, 18-adjusting button, 16-nylon agraffe negative pole, 17-nylon agraffe negative pole, 15-object wearing device pocket.
Fig. 8 is an object wearing device limb protecting belt of the present invention; 23-nylon agraffe positive pole among the figure, 22-air-vent, 21-anticoagulant syringe protecting belt.
Fig. 9 is the dialyser or the filter belt dressing of object wearing device; 24-nylon agraffe positive pole among the figure.
As shown in Figure 1: connect ductus arteriosus (2) and venous duct (6) respectively at the two ends of dialyser or transfusion filters (1), be connected on the ductus arteriosus (2) and append anticoagulant conduit (3), anticoagulant syringe (4) and blood sampling hole (5); Be connected to blood sampling hole (7) and transfusion, dosing short tube (8) on the venous duct (6).Connect dialysis solution conduit (9), (11) and dialyzate bag (10) respectively and (12) promptly form hemodiafiltration system of the present invention at two dialysate holes of dialyser or filter (1).Be connected with the patient and do treatment through the anticoagulant reserve of substituting the bad for the good in advance of sterilization flushing emptying gas.
As shown in Figure 2:, after vein connects, promptly begin dialysis, filtering therapy ready hemodiafiltration system and patient's tremulous pulse.
As shown in Figure 3: have the patient forearm of external arteriovenous fistula pipe to be placed in the limb protecting belt (20) earlier, again dialyser or filter (1) are placed its protecting band (25), empty dialyzate bag (10) or (12) are placed in the object wearing device pocket (15), full dialyzate bag (12) or (10) are placed on object wearing device link or the pocket (19), and the patient can be free movable in dialysis, filtering therapy process.
As shown in Figure 4: on one's body the dialysis filtration device was worn on, desirable seat, clinostatism carried out the hemodiafiltration treatment indoor, regularly change dialyzate bag (10) or (12).Append anticoagulant, do not need the dialyser of anticoagulant or filter then not to add as using.
As shown in Figure 5: when rescuing with patients such as hypotensive renal failure, the wounded, or when adopting vein → venous blood path, available another embodiment of the present invention is promptly located to add at ductus arteriosus (2) and use the blood pump assist circulation, implements successfully to treat.
The used dialysis solution of the each treatment of the present invention has obtained utilizing more fully, has reduced consumption, and each consumption (24000ml/ time) reduces 88% than conventional hemodialysis (CHD) (200,000ml/ time).As prepare high-sodium dialysis solution, bicarbonate dialysate and contain amino acid whose nutrition dialysis solution; Also can do high-sodium dialysis, bicarbonate dialysis and nutrition dialysis.
As shown in Figure 5: after ductus arteriosus, venous duct joined by the mode of Fig. 2 and patient's artery and vein fistula, carry out the malleation hemofiltration earlier or after the ultrafiltration some time, connect dialysis solution again and do dialysis, realized that promptly so-called continuous penetration analyses.
Claims (5)
1, a kind of medical wearable hemodialysis filtration device (PLM type Wearable artificial kidney) and operational approach thereof.The invention is characterized in:
A, hemodiafiltration system are by hollow fiber dialyzer or filter (1), arterial blood circulation conduit (2), tee T and append anticoagulant conduit (3), anticoagulant syringe (4), arterial end blood sampling specimen hole (5), venous blood circulation conduit (6), vein end blood sampling specimen hole (7), transfusion dosing short tube (8), dialysis liquid circulating tube (9) and (11), dialyzate bag (10) and (12), blood pump (13) is formed.
B, object wearing device are by object wearing device bottom (14), object wearing device pocket (15), nylon agraffe negative pole (16) and (17), adjusting button (18), link or pocket (19), limb protecting belt (20), syringe protecting belt (21), the air-vent of various patterns (22), limb protecting belt nylon agraffe positive pole (23), dialyser or filter belt dressing nylon agraffe positive pole (24), dialyser or filter belt dressing (25), the integral body (26) of composition object wearing device.
The operational approach of c, PLM type Wearable artificial kidney is: after the arterial blood circulation conduit (2) of hemodiafiltration system and venous blood circulation conduit (6) are joined with patient's artery and vein fistula respectively, again dialysis liquid circulating tube (9) and (11), full dialyzate bag (10) and empty dialyzate bag (12) join with dialyser or filter (1), full dialyzate bag (10) or (12) are suspended from a high position, empty dialyzate bag (12) or (10) are placed low level, promptly begun the hemodiafiltration treatment.There is the patient upper limb forearm of artery and vein fistula to be placed in the limb protecting belt (20) of object wearing device, dialyser or filter (1) are placed in dialyser or the filter belt dressing (25), full dialyzate bag (10) or (12) place link or pocket (19), and empty dialyzate bag is placed in the object wearing device pocket (15).
2, PLM type Wearable artificial kidney according to claim 1, it is characterized in that: the position of dialyzate bag (10) and (12) is one high and one low, and both replace repeatedly.
3, PLM type Wearable artificial kidney according to claim 1 is characterized in that: on one's body blood pump (13) can be worn on, also can place bed other.
4, PLM type Wearable artificial kidney according to claim 1, it is characterized in that: the material of object wearing device is a synthetic leather, nylon agraffe, yarn fabric band; Also can be leather, or other material.
5, PLM type Wearable artificial kidney according to claim 1, it is characterized in that: the ductus arteriosus of hemodiafiltration system (2), venous duct (6), the material of dialysis liquid circulating tube (10) and (12) is plastics, silication plastics or silicone rubber, the material of tee T are nylon or plastics.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 89108386 CN1051303A (en) | 1989-11-01 | 1989-11-01 | Wearable hemodialysis filter device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 89108386 CN1051303A (en) | 1989-11-01 | 1989-11-01 | Wearable hemodialysis filter device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1051303A true CN1051303A (en) | 1991-05-15 |
Family
ID=4857550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 89108386 Pending CN1051303A (en) | 1989-11-01 | 1989-11-01 | Wearable hemodialysis filter device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1051303A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7597677B2 (en) | 2001-11-16 | 2009-10-06 | National Quality Care, Inc. | Wearable ultrafiltration device |
| US7896830B2 (en) | 2001-11-16 | 2011-03-01 | Fresenius Medical Care Holdings, Inc. | Wearable ultrafiltration device |
| CN102971023A (en) * | 2010-07-05 | 2013-03-13 | 甘布罗伦迪亚股份公司 | An ambulatory ultrafiltration device, related methods and a computer program product |
| CN105771011A (en) * | 2016-01-31 | 2016-07-20 | 陈雯 | Nephritis treatment periodic dialysis apparatus |
| CN107469170A (en) * | 2017-09-29 | 2017-12-15 | 成都威力生生物科技有限公司 | A kind of wearable artificial kidney |
| CN109771720A (en) * | 2019-01-23 | 2019-05-21 | 暨南大学 | A miniature artificial kidney instrument |
| CN110520170A (en) * | 2017-02-07 | 2019-11-29 | 维克托·古拉 | Dialysis system and related methods |
| CN112105329A (en) * | 2018-05-11 | 2020-12-18 | 百时美施贵宝公司 | Devices and systems for delivering combination therapy |
-
1989
- 1989-11-01 CN CN 89108386 patent/CN1051303A/en active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7597677B2 (en) | 2001-11-16 | 2009-10-06 | National Quality Care, Inc. | Wearable ultrafiltration device |
| US7896830B2 (en) | 2001-11-16 | 2011-03-01 | Fresenius Medical Care Holdings, Inc. | Wearable ultrafiltration device |
| US8137299B2 (en) | 2001-11-16 | 2012-03-20 | Fresenius Medical Care Holdings, Inc. | Wearable ultrafiltration device |
| CN102971023A (en) * | 2010-07-05 | 2013-03-13 | 甘布罗伦迪亚股份公司 | An ambulatory ultrafiltration device, related methods and a computer program product |
| CN105771011A (en) * | 2016-01-31 | 2016-07-20 | 陈雯 | Nephritis treatment periodic dialysis apparatus |
| CN110520170A (en) * | 2017-02-07 | 2019-11-29 | 维克托·古拉 | Dialysis system and related methods |
| CN107469170A (en) * | 2017-09-29 | 2017-12-15 | 成都威力生生物科技有限公司 | A kind of wearable artificial kidney |
| CN112105329A (en) * | 2018-05-11 | 2020-12-18 | 百时美施贵宝公司 | Devices and systems for delivering combination therapy |
| CN109771720A (en) * | 2019-01-23 | 2019-05-21 | 暨南大学 | A miniature artificial kidney instrument |
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