CN105105715A - Intelligent sensor used for detecting infection degree of wound and manufacturing method thereof - Google Patents
Intelligent sensor used for detecting infection degree of wound and manufacturing method thereof Download PDFInfo
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- 208000015181 infectious disease Diseases 0.000 title description 10
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000835 fiber Substances 0.000 description 82
- 239000012528 membrane Substances 0.000 description 31
- 239000007793 ph indicator Substances 0.000 description 29
- 239000011230 binding agent Substances 0.000 description 27
- 206010052428 Wound Diseases 0.000 description 20
- 208000027418 Wounds and injury Diseases 0.000 description 20
- 206010072170 Skin wound Diseases 0.000 description 18
- 206010048038 Wound infection Diseases 0.000 description 18
- 238000012544 monitoring process Methods 0.000 description 15
- 238000002835 absorbance Methods 0.000 description 13
- 238000010521 absorption reaction Methods 0.000 description 12
- 238000002360 preparation method Methods 0.000 description 9
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 8
- 239000012530 fluid Substances 0.000 description 8
- 238000006243 chemical reaction Methods 0.000 description 7
- UDSAIICHUKSCKT-UHFFFAOYSA-N bromophenol blue Chemical compound C1=C(Br)C(O)=C(Br)C=C1C1(C=2C=C(Br)C(O)=C(Br)C=2)C2=CC=CC=C2S(=O)(=O)O1 UDSAIICHUKSCKT-UHFFFAOYSA-N 0.000 description 6
- 238000010586 diagram Methods 0.000 description 6
- XJRPTMORGOIMMI-UHFFFAOYSA-N ethyl 2-amino-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate Chemical compound CCOC(=O)C=1SC(N)=NC=1C(F)(F)F XJRPTMORGOIMMI-UHFFFAOYSA-N 0.000 description 6
- 238000005286 illumination Methods 0.000 description 6
- BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 description 5
- 229960003531 phenolsulfonphthalein Drugs 0.000 description 5
- BOTDANWDWHJENH-UHFFFAOYSA-N Tetraethyl orthosilicate Chemical compound CCO[Si](OCC)(OCC)OCC BOTDANWDWHJENH-UHFFFAOYSA-N 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000004744 fabric Substances 0.000 description 4
- 238000002454 metastable transfer emission spectrometry Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- CPUDPFPXCZDNGI-UHFFFAOYSA-N triethoxy(methyl)silane Chemical compound CCO[Si](C)(OCC)OCC CPUDPFPXCZDNGI-UHFFFAOYSA-N 0.000 description 4
- 238000001514 detection method Methods 0.000 description 3
- 239000013307 optical fiber Substances 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 239000003054 catalyst Substances 0.000 description 2
- 239000008367 deionised water Substances 0.000 description 2
- 229910021641 deionized water Inorganic materials 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- 230000000644 propagated effect Effects 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229920000297 Rayon Polymers 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 229910000679 solder Inorganic materials 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Materials For Medical Uses (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The invention discloses an intelligent sensor used for detecting the infection degree of a wound and a manufacturing method thereof. The intelligent sensor comprises a first multimode optical fiber, a second multimode optical fiber and a monomode optical fiber. The monomode optical fiber is located between the first multimode optical fiber and the second multimode optical fiber, and linear connection is formed. The surface of the monomode optical fiber is coated with a PH-sensitive film comprising PH indicators. The PH value of the skin wound is detected through the PH-sensitive film, first-wavelength light is absorbed according to changes, caused by changes of the PH value of the skin wound, of colors of the PH-sensitive film, and the first-wavelength light absorbed by the PH-sensitive film in the monomode optical fiber is transmitted by the second multimode optical fiber to a monitoring device to determine the infection degree of the skin wound. By means of the intelligent sensor, the infection degree of the wound can be detected, so that a doctor or a patient can learn the infection condition of the wound in time and can easily make a pertinent treatment scheme according to the monitoring condition.
Description
Technical field
The present invention relates to wound first-aid equipment, particularly relating to a kind of intelligence sensor for detecting wound infection degree and preparation method thereof.
Background technology
Binder is in order to material that is fixing and protection wound.Common binder has polytype, and the simplest one is single canopy band, is made up of gauze or cotton, is applicable to extremity, afterbody, head and thorax abdomen.Another kind is multiple binder, can make various shape according to body part and shape, and material is double-layer cloth, the Cotton Gossypii of different-thickness can be pressed from both sides between double-layer cloth, periphery has cloth, so that knotting is fixing, as eye bandage, back of the body waist binder, shirtfront binder, abdomen binder etc.
But binder is only only applicable to wrap up anastalsis at present, owing to not having intelligence sensor in current binder, thus cannot carry out Real-Time Monitoring to the gradient of infection of wound, thus make doctor or patient cannot be understood the gradient of infection of wound by binder.
Summary of the invention
Main purpose of the present invention is to provide a kind of intelligence sensor for detecting wound infection degree and preparation method thereof, be applied in binder, be intended to solve the defect that common binder cannot detect the gradient of infection of wound in real time in wound dressing and therapeutic process.
For achieving the above object, the invention provides a kind of intelligence sensor for detecting wound infection degree, described intelligence sensor comprises the first multimode fibre, the second multimode fibre and single-mode fiber, described single-mode fiber between the first multimode fibre and the second multimode fibre and formed straight line connect, wherein:
Described first multimembrane optical fiber, for transferring to monofilm optical fiber by a branch of combined light comprising first wave length light and second wave length light;
Described single-mode fiber surface-coated has one deck to comprise by the PH sensitive membrane of PH indicator, the pH value of this PH sensitive membrane detection of skin wound, and causes the change of PH sensitive membrane color to absorb first wave length light according to the change of the pH value of skin wound;
Described second multimode fibre is sent to monitoring equipment by by the combined light after the PH sensitive membrane absorption in described single-mode fiber, and the gradient of infection of skin wound determined by this monitoring equipment to the default corresponding relation between the absorbance of first wave length light and the pH value of skin wound according to described PH sensitive membrane.
Preferably, described intelligence sensor is connected on the fiber coupler of described monitoring equipment by the first multimode fibre, and the photoelectric diode of described monitoring equipment is connected to by the second multimode fibre, this fiber coupler is connected to the first light source and the secondary light source of described monitoring equipment.
Preferably, the second wave length light that described first light source produces by described fiber coupler and the second wave length light that described secondary light source produces accumulate described combined light, and described combined light are transmitted in described first multimode fibre and propagate.
Preferably, described second wave length light is for correcting by the propagation path of light formed between described first multimode fibre, single-mode fiber and the second multimode fibre.
For achieving the above object, the invention provides a kind of preparation method of the intelligence sensor for detecting wound infection degree, described preparation method comprises step:
PH indicator is immersed in deionized water and purifies;
By the PH indicator after evolving and tetraethyl orthosilicate, MTES be that catalyst is fused into PH sensitive fluid and stirs with hydrochloric acid;
Single-mode fiber is flooded the first Preset Time in PH sensitive fluid, PH sensitive fluid is fully penetrated in single-mode fiber;
Single-mode fiber is taken out from PH sensitive fluid, and at room temperature places the second Preset Time and dry the single-mode fiber that rear formation includes PH sensitive membrane;
By described single-mode fiber, the first multimode fibre and the second multimode fibre are formed straight line to be connected to make intelligence sensor.
Described PH indicator is a kind of bromophenol blue PH indicator, phenol red PH indicator or bromocresol purple PH indicator.
Preferably, described PH indicator is by being that 1:1:1 mixes by the PH indicator of bromophenol blue, phenol red PH indicator and bromocresol purple PH indicator according to weight fraction ratio.
Preferably, described PH indicator, tetraethyl orthosilicate, MTES are 2:1:1:1 with the weight fraction ratio of hydrochloric acid.
Preferably, described first Preset Time is 2 to 3 hours, and described second Preset Time is 72 hours.
Preferably, the length range of described single-mode fiber is 2cm to 4cm, diameter is 100 μm, the length range of described first multimode fibre and the second multimode fibre is respectively 2cm to 4cm, diameter is respectively 200 μm, and the thickness of described PH sensitive membrane 2020 is 500 μm to 600 μm.
Compared to prior art, the intelligent binder of detection wound infection degree of the present invention have employed technique scheme, reach following technique effect: described intelligent binder can detect wound infection degree by intelligence sensor provided by the invention, make doctor or patient understand the situation of wound in time, be conducive to doctor or patient and make therapeutic scheme targetedly according to the situation of monitoring.
Accompanying drawing explanation
Fig. 1 is that the present invention is arranged on the planar structure schematic diagram of preferred embodiment in intelligent binder for the intelligence sensor detecting wound infection degree;
Fig. 2 is that the present invention is for detecting the planar structure schematic diagram of the intelligence sensor preferred embodiment of wound infection degree;
Fig. 3 is positioned at the view of skin wound when to be the present invention use for the intelligence sensor detecting wound infection degree;
Fig. 4 is the schematic diagram of the present invention for the intelligence sensor detecting wound infection degree and the monitoring equipment preferred embodiment be connected.
Fig. 5 is that the present invention is for detecting the flow chart of the preparation method preferred embodiment of the intelligence sensor of wound infection degree.
The realization of the object of the invention, functional characteristics and advantage will in conjunction with the embodiments, are described further with reference to accompanying drawing.
Detailed description of the invention
For further setting forth the present invention for the technological means reaching above-mentioned purpose and take and effect, below in conjunction with accompanying drawing and preferred embodiment, describe in detail bright to the specific embodiment of the present invention, structure, feature and effect thereof.Should be appreciated that specific embodiment described in the invention only in order to explain the present invention, be not intended to limit the present invention.
As shown in Figure 1, Fig. 1 is that the present invention is arranged on the planar structure schematic diagram of preferred embodiment in intelligent binder for the intelligence sensor detecting wound infection degree.In the present embodiment, described intelligent binder include but not limited to, binder body 2 and the intelligence sensor 20 be arranged on the sticking veneer of binder body 2.This sticking veneer is provided with medical viscose glue, makes binder body 2 can be pasted on the skin of human body and not come off.Described intelligence sensor 20 can be positioned at the optional position of the sticking veneer of binder body 2, as long as described binder body 2 can cover described intelligence sensor 20 completely.Described binder body 2 may be, but not limited to, medical proof fabric or gauze.
Shown in composition graphs 2, be that the present invention is for detecting the planar structure schematic diagram of the intelligence sensor preferred embodiment of wound infection degree.In this enforcement Lee, described intelligence sensor 20 comprises the first multimode fibre 201, second multimode fibre 203 and single-mode fiber 202, described single-mode fiber 202 between the first multimode fibre 201 and the second multimode fibre 203 and formed straight line connect.Described first multimode fibre 201, second multimode fibre 203 and single-mode fiber 202 are cylindrical.
Described single-mode fiber 202 surface coverage has one deck PH sensitive membrane 2020, and this PH sensitive membrane 2020 adopts colloidal sol and gel method preparation (please refer to Fig. 5 to describe).This PH sensitive membrane 2020 comprises by one or more pH value indicators, and specifically, described pH value indicator comprises bromophenol blue indicator, phenolic red indicator or bromocresol purple indicator.In order to increase the sensitive range of pH value, three kinds of PH indicators can be adopted to mix, namely respectively the PH indicator of the PH indicator of bromophenol blue, phenol red PH indicator and bromocresol purple is mixed than for 1:1:1 according to weight fraction, the indicator mixed by these three kinds of PH indicators can detect that scope is the pH value of 2-9, be 590nm to the maximum absorption wavelength of light, and absorption function is not had to the light of 860nm wavelength.By the pH value indicator in described PH sensitive membrane 2020, described intelligence sensor 20 can monitor the pH value (being worth 9.0 from pH value 2.0 can monitor) of skin wound 3.By monitoring the pH value of skin wound, the gradient of infection of skin wound can be judged.Such as, pH value is normal between 4.0 to 4.5, and represent not infecting of skin wound, pH value is abnormal between 7.5 to 9.0, represents skin wound inflammation.Specifically, when the pH value change of skin wound, the color of the pH value indicator in PH sensitive membrane 2020 changes, thus also changes to the absorbance of first wave length light.
Shown in composition graphs 3, Fig. 3 be intelligent binder that the present invention detects wound infection degree when using intelligence sensor be positioned at the view of skin wound.In the present embodiment, the shape of described binder body 2 may be, but not limited to, rectangle, square, circle etc.In the present embodiment, for the ease of monitoring the gradient of infection of wound, described intelligence sensor 20 is in the centre position of described binder body, when making binder body just in time be pasted on the wound of skin 2, described intelligence sensor 20 is positioned at the position (region that in other words, wound is the most serious) of the wound of skin 3.When on the wound that binder body 2 is pasted on skin 2, described intelligence sensor 20 is positioned at the wound of skin 3.
As shown in Figure 4, Fig. 4 is the schematic diagram of the present invention for the intelligence sensor detecting wound infection degree and the monitoring equipment preferred embodiment be connected.In the present embodiment, described monitoring equipment 1 comprises photodiode 10, first light source 121, secondary light source 122, fiber coupler 14, processor 16 and display device 18.Wherein, described first light source 121 and secondary light source 122 are connected with described fiber coupler 14, and described photodiode 10 is connected with described processor 16, and described processor 16 is connected with described display device 18.
First wave length light for generation of first wave length light, and is sent to described fiber coupler 14 by described first light source 121.In the present embodiment, described first wave length light is the light of 590 nanometers.
Second wave length light for generation of second wave length light, and is sent to described fiber coupler 14 by described secondary light source 122.In the present embodiment, described second wave length light is the light of 860 nano wave lengths.
First wave length light and second wave length light are accumulated a branch of combined light by described fiber coupler 14, and correct by the propagation path of light formed between described first multimode fibre 201, single-mode fiber 202 and the second multimode fibre 203.Specifically, the light (i.e. first wave length light and second wave length light) of two bundle different wave lengths is become a branch of combined light by refraction and transmission by described fiber coupler 14, that is, makes the propagation path of light of two bundle different wave lengths reach consistent.
First wave length light in combined light and second wave length light (i.e. optical signal) for receiving combined light, and are converted to the corresponding signal of telecommunication by described photoelectric diode 10.
Described processor 16 is for obtaining the signal of telecommunication of first wave length light corresponding conversion and the signal of telecommunication of second wave length light corresponding conversion from described photodiode 10, and analyzing and processing is carried out, to obtain the monitoring result of the gradient of infection of skin wound to the signal of telecommunication of described first wave length light corresponding conversion and the signal of telecommunication of second wave length light corresponding conversion.
Described display device 18 is for the signal of telecommunication of the signal of telecommunication and second wave length light corresponding conversion that show described first wave length light corresponding conversion, further, described display device 18 is also for the healing of the absorption variations trend and wound that show PH sensitive membrane 2020 pairs of first wave length light.
Described fiber coupler 14 is connected with the first multimode fibre 201, described second multimode fibre 203 is connected with photoelectric diode 10, combined light (be namely a branch of combined light that the light of 590 nanometers and the light of 860 nano wave lengths combine by wavelength) is transmitted into the first multimode fibre 201 by described fiber coupler 14, makes combined light pass the first multimode fibre 201, single-mode fiber 202 and the second multimode fibre 203.
When described combined light is propagated in described single-mode fiber 202, the absorption that described PH sensitive membrane 2020 can be carried out in various degree to first wave length light, and described PH sensitive membrane 2020 affected the change of the absorbance of first wave length light by the pH value of skin wound.Have default corresponding relation between the absorbance of described PH sensitive membrane 2020 pairs of first wave length light and the pH value of skin wound, specifically, the pH value of skin wound is larger, and the absorbance of described PH sensitive membrane 2020 pairs of first wave length light is higher.There is default corresponding relation to test according to great many of experiments between the absorbance of described PH sensitive membrane 2020 pairs of first wave length light and the pH value of skin wound to obtain, and be stored in monitoring equipment 1.Such as, when pH value is 2, the absorbance of described PH sensitive membrane 2020 pairs of first wave length light is 0, if when pH value is 4, the absorbance of described PH sensitive membrane 2020 pairs of first wave length light is 10%.
In the present embodiment, it should be noted that, described photoelectric diode 10 obtains first wave length light from described second multimode fibre 203, and converting described first wave length light to the signal of telecommunication, the signal of telecommunication converted to according to described first wave length light calculates the absorbance of described PH sensitive membrane 2020 pairs of first wave length light.The described signal of telecommunication refers on photodiode 10 because produced photoelectric current is penetrated in first wave length illumination.Wherein, the intensity of first wave length light is directly proportional to described photoelectric current.Described PH sensitive membrane 2020 pairs of first wave length light carry out absorption in various degree, can weaken the intensity of first wave length light.
In the present embodiment, the absorbance of described PH sensitive membrane 2020 pairs of first wave length light is mapped to the rate of change of the photoelectric current that photoelectric diode 10 produces for first wave length illumination.Specifically, a=c/b, wherein, b be described first wave length light by absorption time, the photoelectric current that described photoelectric diode 10 obtains, if when c is described first wave length light by the absorption in various degree of described PH sensitive membrane 2020, the photoelectric current that described photoelectric diode 10 obtains, a is the rate of change of photoelectric current, namely the absorbance of described PH sensitive membrane 2020 pairs of first wave length light.
When described combined light is propagated in described single-mode fiber 202, described PH sensitive membrane 2020 can not absorb described second wave length light, and whether the propagation path of light that can be corrected by being formed between described first multimode fibre 201, single-mode fiber 202 and the second multimode fibre 203 by second wave length light is correct.Specifically, described photoelectric diode 10 obtains second wave length light from described second multimode fibre 203, and converts described second wave length light to the signal of telecommunication.The described signal of telecommunication refers on photodiode 10 because produced photoelectric current is penetrated in second wave length illumination.If described second wave length illumination penetrates produced photoelectric current in preset range (such as, between 30 microamperes to 40 microamperes), then show that the propagation path of light of combined light is correct, if described second wave length illumination penetrate produced photoelectric current not in preset range (such as, between 30 microamperes to 40 microamperes), show that the propagation path of combined light is incorrect, then adjust fiber coupler 14, make described second wave length illumination penetrate produced photoelectric current in preset range.
As shown in Figure 5, Fig. 5 is that the present invention is for detecting the flow chart of the preparation method preferred embodiment of the intelligence sensor of wound infection degree.In the present embodiment, the preparation method of the described intelligence sensor 20 for detecting wound infection degree comprises step:
Step S21: PH indicator is immersed in deionized water and purifies;
In the present embodiment, described PH indicator can be the one of the PH indicator of the PH indicator of bromophenol blue, phenol red PH indicator and bromocresol purple.In other embodiments, in order to increase the sensitive range of pH value, three kinds of PH indicators can be adopted to mix, namely respectively the PH indicator of the PH indicator of bromophenol blue, phenol red PH indicator and bromocresol purple is mixed than for 1:1:1 according to weight fraction, the indicator mixed by these three kinds of PH indicators can detect that scope is the pH value of 2-9, be 590nm to the maximum absorption wavelength of light, and absorption function is not had to the light of 860nm wavelength;
Step S22: by the PH indicator after evolving and tetraethyl orthosilicate, MTES be that catalyst is fused into PH sensitive fluid and stirs with hydrochloric acid;
In the present embodiment, described PH indicator, tetraethyl orthosilicate, MTES are 2:1:1:1 with the weight fraction ratio of hydrochloric acid, to reach the effect detected the scope pH value that is 2-9, and be 590nm to the maximum absorption wavelength of light, and 860nm wavelength is not absorbed.
Step S23: single-mode fiber 202 is flooded the first Preset Time in PH sensitive fluid, makes PH sensitive fluid fully penetrate on single-mode fiber 202;
In the present embodiment, described first Preset Time is 2 to 3 hours, and the length of described single-mode fiber 202 is 2-4cm, diameter is 100 μm;
Step S24: single-mode fiber 202 is taken out from PH sensitive fluid and makes at room temperature placing after the second Preset Time dries the single-mode fiber 202 including PH sensitive membrane 2020;
In the present embodiment, described second Preset Time is 72 hours, and the thickness of described PH sensitive membrane 2020 is 500 μm to 600 μm.
Step S25: by described single-mode fiber 202, first multimode fibre 201 and the second multimode fibre 203 are formed straight line and be connected to make intelligence sensor 20; In the present embodiment, the length of described first root multimode fiber 201 and the second root multimode fiber 203 is for 2-4cm, diameter are respectively 200 μm respectively.
This enforcement adopts existing fiber solder technology by the first multimode fibre 201, forms seamless straight wire bonding between single-mode fiber 202 and the second multimode fibre 203.Described first multimode fibre 201, single-mode fiber 202 and the second multimode fibre 203 all adopt existing technique to make, and such as polymer coated glass optical fiber and polymethyl methacrylate (PMMA) fiber are made.Because PH sensitive membrane 2020 can detect that scope is the pH value of 2-9, be therefore the first wave length light of 590nm to the maximum absorption wavelength of light, and the second wave length light of 860nm wavelength is not absorbed.By the pH value indicator in described PH sensitive membrane 2020, described intelligence sensor 20 can monitor the pH value (being worth 9.0 from pH value 2.0 can monitor) of wound 3.By monitoring the pH value of wound 3, the gradient of infection of wound 3 can be judged.Such as, pH value is normal between 4.0 to 4.5, and represent not infecting of wound 3, pH value is abnormal between 7.5 to 9.0, represents wound 3 inflammation.Specifically, when the pH value change of wound 3, the color of the pH value indicator in PH sensitive membrane 2020 changes, thus also changes to the absorbance of first wave length light.By the rate of change of the absorbance of analysis list mode fiber 202 pairs of first wave length light, described intelligence sensor 20 gets final product the gradient of infection of detection of skin wound.
These are only the preferred embodiments of the present invention; not thereby the scope of the claims of the present invention is limited; every utilize description of the present invention and accompanying drawing content to do equivalent structure or equivalent function conversion; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present invention.
Claims (10)
1. one kind for detecting the intelligence sensor of wound infection degree, it is characterized in that, described intelligence sensor comprises the first multimode fibre, the second multimode fibre and single-mode fiber, described single-mode fiber between the first multimode fibre and the second multimode fibre and formed straight line connect, wherein:
Described first multimembrane optical fiber, for transferring to monofilm optical fiber by a branch of combined light comprising first wave length light and second wave length light;
Described single-mode fiber surface-coated has one deck to comprise by the PH sensitive membrane of PH indicator, the pH value of this PH sensitive membrane detection of skin wound, and causes the change of PH sensitive membrane color to absorb first wave length light according to the change of the pH value of skin wound;
Described second multimode fibre is sent to monitoring equipment by by the combined light after the PH sensitive membrane absorption in described single-mode fiber, and the gradient of infection of skin wound determined by this monitoring equipment to the default corresponding relation between the absorbance of first wave length light and the pH value of skin wound according to described PH sensitive membrane.
2. as described in the intelligence sensor for detecting wound infection degree of claim 1, it is characterized in that, described intelligence sensor is connected on the fiber coupler of described monitoring equipment by the first multimode fibre, and the photoelectric diode of described monitoring equipment is connected to by the second multimode fibre, this fiber coupler is connected to the first light source and the secondary light source of described monitoring equipment.
3. as described in the intelligence sensor for detecting wound infection degree of claim 2, it is characterized in that, the second wave length light that described first light source produces by described fiber coupler and the second wave length light that described secondary light source produces accumulate described combined light, and described combined light are transmitted in described first multimode fibre and propagate.
4. as described in the intelligence sensor for detecting wound infection degree of claim 3, it is characterized in that, described second wave length light is for correcting by the propagation path of light formed between described first multimode fibre, single-mode fiber and the second multimode fibre.
5. a preparation method for the intelligence sensor as described in any one of Claims 1-4, is characterized in that, described preparation method comprises step:
PH indicator is immersed in deionized water and purifies;
By the PH indicator after evolving and tetraethyl orthosilicate, MTES be that catalyst is fused into PH sensitive fluid and stirs with hydrochloric acid;
Single-mode fiber is flooded the first Preset Time in PH sensitive fluid, PH sensitive fluid is fully penetrated in single-mode fiber;
Single-mode fiber is taken out from PH sensitive fluid, and at room temperature places the second Preset Time and dry the single-mode fiber that rear formation includes PH sensitive membrane;
By described single-mode fiber, the first multimode fibre and the second multimode fibre are formed straight line to be connected to make intelligence sensor.
6. the preparation method of intelligence sensor as claimed in claim 5, it is characterized in that, described PH indicator is a kind of bromophenol blue PH indicator, phenol red PH indicator or bromocresol purple PH indicator.
7. the preparation method of intelligence sensor as claimed in claim 5, is characterized in that, described PH indicator is by being that 1:1:1 mixes by the PH indicator of bromophenol blue, phenol red PH indicator and bromocresol purple PH indicator according to weight fraction ratio.
8. the preparation method of intelligence sensor as claimed in claim 5, is characterized in that, described PH indicator, tetraethyl orthosilicate, MTES are 2:1:1:1 with the weight fraction ratio of hydrochloric acid.
9. the preparation method of intelligence sensor as claimed in claim 5, it is characterized in that, described first Preset Time is 2 to 3 hours, and described second Preset Time is 72 hours.
10. the preparation method of intelligence sensor as claimed in claim 5, it is characterized in that, the length range of described single-mode fiber is 2cm to 4cm, diameter is 100 μm, the length range of described first multimode fibre and the second multimode fibre is respectively 2cm to 4cm, diameter is respectively 200 μm, and the thickness of described PH sensitive membrane 2020 is 500 μm to 600 μm.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510581466.XA CN105105715A (en) | 2015-09-12 | 2015-09-12 | Intelligent sensor used for detecting infection degree of wound and manufacturing method thereof |
| PCT/CN2015/098612 WO2017041384A1 (en) | 2015-09-12 | 2015-12-24 | Smart sensor used for measuring extent of infection of wound, and method for fabricating same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510581466.XA CN105105715A (en) | 2015-09-12 | 2015-09-12 | Intelligent sensor used for detecting infection degree of wound and manufacturing method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105105715A true CN105105715A (en) | 2015-12-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510581466.XA Pending CN105105715A (en) | 2015-09-12 | 2015-09-12 | Intelligent sensor used for detecting infection degree of wound and manufacturing method thereof |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN105105715A (en) |
| WO (1) | WO2017041384A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017041384A1 (en) * | 2015-09-12 | 2017-03-16 | 深圳市前海颐老科技有限公司 | Smart sensor used for measuring extent of infection of wound, and method for fabricating same |
| CN111135341A (en) * | 2020-01-20 | 2020-05-12 | 浙江大学 | A smart hydrogel dressing for early warning and controllable treatment of infected wounds |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180289556A1 (en) | 2017-04-11 | 2018-10-11 | Ipcapital Group, Inc. | Wound covering apparatus |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5081041A (en) * | 1990-04-03 | 1992-01-14 | Minnesota Mining And Manufacturing Company | Ionic component sensor and method for making and using same |
| AT401111B (en) * | 1995-02-01 | 1996-06-25 | Avl Verbrennungskraft Messtech | METHOD FOR CALIBRATING A PH MEASURING ELEMENT |
| DE102008021575A1 (en) * | 2008-04-30 | 2009-11-05 | Neue Magnetodyn Gmbh | Device for stimulating a healing process |
| CN101982760A (en) * | 2010-09-20 | 2011-03-02 | 北京邮电大学 | Optical fiber pH meter |
| CN103645141B (en) * | 2013-11-16 | 2016-04-27 | 中山欧麦克仪器设备有限公司 | A kind of optical fiber pH meter |
| CN105105715A (en) * | 2015-09-12 | 2015-12-02 | 深圳市前海安测信息技术有限公司 | Intelligent sensor used for detecting infection degree of wound and manufacturing method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017041384A1 (en) * | 2015-09-12 | 2017-03-16 | 深圳市前海颐老科技有限公司 | Smart sensor used for measuring extent of infection of wound, and method for fabricating same |
| CN111135341A (en) * | 2020-01-20 | 2020-05-12 | 浙江大学 | A smart hydrogel dressing for early warning and controllable treatment of infected wounds |
| CN111135341B (en) * | 2020-01-20 | 2021-10-29 | 浙江大学 | A smart hydrogel dressing for early warning and controllable treatment of infected wounds |
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| WO2017041384A1 (en) | 2017-03-16 |
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