CN105097417A - Control and data acquisition system for quadrupole mass spectrometers - Google Patents
Control and data acquisition system for quadrupole mass spectrometers Download PDFInfo
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- CN105097417A CN105097417A CN201510524762.6A CN201510524762A CN105097417A CN 105097417 A CN105097417 A CN 105097417A CN 201510524762 A CN201510524762 A CN 201510524762A CN 105097417 A CN105097417 A CN 105097417A
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Abstract
A control and data acquisition system for quadrupole mass spectrometers belongs to the technical field of mass spectrometers. The data acquisition system comprises a digital-to-analog conversion module used to generate control voltage, a level conversion module used to modulate pulse signals sent by a preamplifier, a data acquisition module coupled to the level conversion module and used to acquire and count the signals after modulation, and a control module coupled to the digital-to-analog conversion module and the data acquisition module and used to output the control voltage according to a value set by a computer after the value is converted by the digital-to-analog conversion module and further used to control data acquisition of the data acquisition module according to the data acquisition process and transmit acquired data to the computer for data processing. By adopting the control and data acquisition system provided by the invention, control on a quadrupole radio-frequency power supply and data acquisition of an instrument are realized, and the degree of precision control on and automation of the instrument is improved.
Description
Technical field
The invention belongs to mass spectrometry art field, particularly relate to the control acquisition system for radio-frequency power supply Control & data acquisition in a kind of quadrupole mass spectrometer.
Background technology
Mass spectrometer is the different isotopic instrument of a kind of separation and detection, and its principle is the principle that can deflect at elect magnetic field according to charged particle, carries out a quasi-instrument of separation and detection material composition by the mass discrepancy of material atom, molecule or molecular fragment.
Mass spectrometer mainly consists of the following components: sample introduction system, ion source, interface section, ion focusing system, mass analyzer, detection system etc., wherein, mass analyzer is its core.Different with principle according to the kind of mass analyzer, mass spectrometer can be divided into the rotatable mass spectrometer of magnetic biasing, ion trap mass spectrometer (IT-MS), time-of-flight mass spectrometer (TOF-MS), fourier transform ion cyclotron resonance mass spectrometer (FTICR-MS) and quadrupole mass spectrometer (Q-MS) etc.And wherein, quadrupole mass spectrometer is the most ripe at present and most widely used one.
Quadrupole rod mass analyzer is generally made up of the cylindrical or bi-curved metal bar of 4 equal length and diameter, length is generally 150 ~ 200mm, the about 10mm of diameter, operating frequency is 2 ~ 3MHz, mainly play the effect be separated according to mass-to-charge ratio by ion, the realization of this function controls radio-frequency power supply by control circuit, be that the direct current of U and V and radio frequency are applied to every root extremely on rod by amplitude, a pair extremely rod be just, another is negative to extremely rod, be applied to often pair of voltage extremely on rod and all there is same amplitude, but phase 180 °.Analyzed ion is introduced into one end of quadrupole rods device vertically, the radio-frequency voltage applied makes all ion deflectings enter an oscillation path and passes through extremely rod, suitably select radio frequency and direct voltage, then only have given m/z ion could obtain stable path and pass through extremely rod, export from its other end, other ions will too be deflected, and collide with extremely excellent, and be neutralized on extremely rod and lose, thus achieve the function of isolating ions.
Quadrupole rod mass analyzer system finally introduces detector after being separated by mass-to-charge ratio by ion, and detector converts ion to electronic impulse, then premenstrual for this faint small-signal amplification module process is amplified, sends to data acquisition module to carry out acquisition counter.The size of count value is relevant with the concentration analyzing ion in sample, by the standard comparing with concentration known, realizes the quantitative analysis of the trace element of unknown sample.
Summary of the invention
The object of the present invention is to provide a kind of control for quadrupole mass spectrometer and data acquisition system, adopt the framework that combines of ARM and FPGA, utilize ARM chip peripheral hardware enriches, communication function is powerful and control ability is strong advantage and computer to carry out communication; Utilize that fpga chip parallel processing capability is strong and fireballing advantage carries out voltage control and data acquisition counts.Specific as follows:
A kind of control acquisition system, for the control of radio-frequency power supply in mass spectrometer, and then realize by the screening of measured ion, acquisition counter is carried out to detector system electronic pulse signal out simultaneously, and be uploaded to computer and carry out data processing.Comprise control module, communication module, D/A converter module, data acquisition module, level switch module and amplifier modulation module.
Wherein control module, is connected by CAN with communication module, and is coupled to D/A converter module and data acquisition module, for exporting control voltage according to computer installation value after D/A converter module conversion; Meanwhile, carry out data acquisition according to data acquisition flow control data acquisition module, and image data is transferred to computer and carry out data processing.
Communication module, is coupled to control module and computer, for the data communication between control module and computer.
D/A converter module, is coupled to control module and amplifier modulation module, for generation of the control voltage of quadrupole rod radio-frequency power supply.
Data acquisition module, is coupled to control module and level switch module, for carrying out acquisition counter to the signal after modulation.
Level switch module, is coupled to data acquisition module, for modulating front putting the pulse signal transmitted.
Amplifier modulation module, is coupled to D/A converter module, and the voltage exported for logarithmic mode modular converter carries out modulating and obtains required magnitude of voltage.
As from the foregoing, in control acquisition system proposed by the invention, control module by communication module according to computer installation value, control D/A converter module on the one hand and export control voltage, this control voltage, after the modulation of amplifier modulation module, is exported to quadrupole rod radio-frequency power supply and is produced quadrupole rod required voltage; On the other hand control module is according to whole data acquisition flow, and pulse signal is input to data acquisition module and carries out acquisition counter by control level modular converter, and count value is passed to computer by communication module carries out data processing.
Accompanying drawing explanation
Fig. 1 is the module diagram of the control acquisition system of embodiments of the present invention.
Embodiment
In order to make relevant technical staff in the field understand technical scheme of the present invention better, below in conjunction with the accompanying drawing of embodiment of the present invention, the technical scheme in embodiment of the present invention is clearly and completely described.
About occurred herein " coupling ", the direct connection of two modules (or unit, element) can be referred to, also can refer to the indirect connection of two modules (or unit, element), namely also there are other modules (or unit, element) between two modules (or unit, element).
The module diagram of the control acquisition system of an embodiment of the present invention is depicted with reference to Fig. 1, Fig. 1.
In present embodiment, control module, is connected by CAN with communication module, and is coupled to D/A converter module and data acquisition module, for exporting control voltage according to computer installation value after D/A converter module conversion; Meanwhile, carry out data acquisition according to data acquisition flow control data acquisition module, and image data is transferred to computer and carry out data processing.
Communication module, is coupled to control module and computer, for the data communication between control module and computer.
D/A converter module, is coupled to control module and amplifier modulation module, for generation of the control voltage of quadrupole rod radio-frequency power supply.
Data acquisition module, is coupled to control module and level switch module, for carrying out acquisition counter to the signal after modulation.
Level switch module, is coupled to data acquisition module, for modulating front putting the pulse signal transmitted.
Amplifier modulation module, is coupled to D/A converter module, and the voltage exported for logarithmic mode modular converter carries out modulating and obtains required magnitude of voltage.
Below only have expressed some embodiments of the present invention, it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.
Claims (1)
1. for control and the data acquisition system of quadrupole mass spectrometer, it is characterized in that, comprise control module, communication module, D/A converter module, data acquisition module, level switch module and amplifier modulation module;
Control module is connected by CAN with communication module, and is coupled to D/A converter module and data acquisition module, for exporting control voltage according to computer installation value after D/A converter module conversion; Meanwhile, carry out data acquisition according to data acquisition flow control data acquisition module, and image data is transferred to computer and carry out data processing;
Communication module is coupled to control module and computer, for the data communication between control module and computer;
D/A converter module is coupled to control module and amplifier modulation module, for generation of the control voltage of quadrupole rod radio-frequency power supply;
Data acquisition module is coupled to control module and level switch module, for carrying out acquisition counter to the signal after modulation;
Level switch module is coupled to data acquisition module, for modulating front putting the pulse signal transmitted;
Amplifier modulation module is coupled to D/A converter module, and the voltage exported for logarithmic mode modular converter carries out modulating and obtains required magnitude of voltage.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510524762.6A CN105097417A (en) | 2015-08-24 | 2015-08-24 | Control and data acquisition system for quadrupole mass spectrometers |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510524762.6A CN105097417A (en) | 2015-08-24 | 2015-08-24 | Control and data acquisition system for quadrupole mass spectrometers |
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| CN105097417A true CN105097417A (en) | 2015-11-25 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105843133A (en) * | 2016-05-27 | 2016-08-10 | 安图实验仪器(郑州)有限公司 | Matrix-assisted laser desorption/ionization time-of-flight mass spectrometer XY platform control system |
| CN111045352A (en) * | 2019-07-16 | 2020-04-21 | 天津国科医工科技发展有限公司 | Zynq platform-based mass spectrometer data acquisition device and method |
| CN112014456A (en) * | 2020-08-28 | 2020-12-01 | 中检集团南方测试股份有限公司 | High-precision drug detection and analysis system |
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| WO2007130649A2 (en) * | 2006-05-03 | 2007-11-15 | California Institute Of Technology | Electronic drive and acquisition system for mass spectrometry |
| CN103956932A (en) * | 2014-04-02 | 2014-07-30 | 上海大学 | High-voltage pulse power supply for time-of-flight mass spectrometer |
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2015
- 2015-08-24 CN CN201510524762.6A patent/CN105097417A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2007130649A2 (en) * | 2006-05-03 | 2007-11-15 | California Institute Of Technology | Electronic drive and acquisition system for mass spectrometry |
| CN103956932A (en) * | 2014-04-02 | 2014-07-30 | 上海大学 | High-voltage pulse power supply for time-of-flight mass spectrometer |
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| 江游等: "四极质谱仪通用数字控制系统结构的研究", 《质谱学报》 * |
| 陈永奎: "基于ARM的四极质谱仪数据系统的研究与实现", 《东南大学硕士论文》 * |
| 马宗骥等: "基于FPGA+ARM的数据采集系统设计", 《化工自动化及仪表》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105843133A (en) * | 2016-05-27 | 2016-08-10 | 安图实验仪器(郑州)有限公司 | Matrix-assisted laser desorption/ionization time-of-flight mass spectrometer XY platform control system |
| CN111045352A (en) * | 2019-07-16 | 2020-04-21 | 天津国科医工科技发展有限公司 | Zynq platform-based mass spectrometer data acquisition device and method |
| CN112014456A (en) * | 2020-08-28 | 2020-12-01 | 中检集团南方测试股份有限公司 | High-precision drug detection and analysis system |
| CN112014456B (en) * | 2020-08-28 | 2021-04-09 | 中检集团南方测试股份有限公司 | High-precision drug detection and analysis system |
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Application publication date: 20151125 |