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CN105031254A - Ointment used for treating dermatitis and preparation method thereof - Google Patents

Ointment used for treating dermatitis and preparation method thereof Download PDF

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CN105031254A
CN105031254A CN201510393992.3A CN201510393992A CN105031254A CN 105031254 A CN105031254 A CN 105031254A CN 201510393992 A CN201510393992 A CN 201510393992A CN 105031254 A CN105031254 A CN 105031254A
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vitamin
dermatitis
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radix
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CN105031254B (en
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王睿超
姚晓渝
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SHANDONG JIACITANG BIOLOGICAL TECHNOLOGY Co Ltd
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Abstract

The invention relates to an ointment used for treating dermatitis and a preparation method thereof, belonging to the technical field of traditional Chinese medicinal preparations. The ointment used for treating dermatitis mainly comprises active components like honeysuckle flower, bletilla striata, dahurian angelica root, Japanese snakegourd root, calamine, aloe, borneol, wild chrysanthemum flower, fructus forsythia, lightyellow sophora root, red sage root, white batryticated silkworm, largetrifoliolious bugbane rhizome, mulberry leaf, fructus tribuli, divaricate saposhnikovia root, periostracum cicadae, etc. and also comprises accessory materials. Through effective and reasonable combination, mutual cooperation and joint promotion of all the components, the obtained ointment specifically targeted at dermatitis has substantial drug effect, is applicable to a variety of dermatitis like infantile eczema, autosensitive eczema and infectious eczematoid dermatitis, has the advantages of good curative effect, short treatment course, fast action, strong effect, no irritation, safety and reliability, can fundamentally treat dermatitis, shows itching-relieving, acne-removing and spot-removing effect and exerts the effective effect of simultaneous treatment of principal and subordinate symptoms.

Description

A kind of unguentum for the treatment of dermatitis and preparation method thereof
(1) technical field
The invention belongs to technical field of traditional Chinese medicine preparation, particularly a kind of unguentum for the treatment of dermatitis and preparation method thereof.
(2) background technology
Dermatitis is a kind of scytitis reaction of the acute pruritus caused by multiple internal and external factor, comprises the various dermatitis such as diaper dermatitis, contact dermatitis, atoipc dermatitis, eczema-like dermatitis.Dermatitis divides acute, subacute, chronic three phases.Acute stage, tool oozed out tendency, and chronic phase then infiltrates, plumpness.Some patient directly translates into chronic eczema.Skin lesion has pleomorphism, symmetry, pruritus and the easy feature such as recurrent exerbation, the study affecting child with become task efficiency, be the common disease that a kind of many paathogenic factors cause.Existing medicine for external use such as the above-mentioned dermatitis of the treatment such as PIYANPING, PIKANGWANG is difficult to reach the cause of disease, old complaint, complication three comprehensive therapeutical effect, therapeutic effect may be had for above-mentioned dermatosis severe type, if but use for a long time, also effect can be lost, and significantly even not invalid for such effect of drugs of type of state of an illness complexity.Also have the Chinese medicine being used for the treatment of dermatitis or eczema at present, mostly be oral Chinese herbal medicine, Chinese patent medicine, kind is many, and effect is remarkable, and late result is not good, and some external Chinese medicine ointment preparations are because being often mixed with amcinonide in ointment, and curative effect is very micro-, and easy recurrent exerbation.
(3) summary of the invention
In order to make up the deficiencies in the prior art, the invention provides a kind of prepare simple, with strong points, prove effective fast, evident in efficacy and unguentum of the treatment dermatitis had no side effect and preparation method thereof.The unguentum of this treatment dermatitis uses easy to carry, the discomfort of dermatitis, eczema acute pruritus can be alleviated, to severe skin disease such as various dermatitis, eczema, impetigo, there is good therapeutical effect, not containing any hormone medicine, short treating period, late result is good, does not produce any side effect, sequela shape not easily recurs, cure rate is high, and the short-term and the prolonged sickness that solve patient are painful.
The present invention is achieved through the following technical solutions:
Treat a unguentum for dermatitis, its active component is made up of the raw material of following parts by weight:
Flos Lonicerae 10-20 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 part, Radix Angelicae Dahuricae 10-20 part, soil melon root powder 10-20 part, Calamina 15-25 part, Aloe 10-20 part, Borneolum Syntheticum 4-7 part, Flos Chrysanthemi Indici 10-15 part, Fructus Forsythiae 4-8 part, Radix Sophorae Flavescentis 4-6 part, Radix Salviae Miltiorrhizae 5-10 part, Bombyx Batryticatus 5-10 part, Rhizoma Cimicifugae 5-10 part, Folium Mori 2-6 part, Fructus Atriplicis Sibiricae 4-8 part, Radix Saposhnikoviae 10-20 part, Periostracum Cicadae 15-25 part;
Also comprise the adjuvant of following parts by weight: vitamin B12-8 parts, vitamin B2 2-8 part, Catergen-8 parts, vitamin E2-8 parts, dehydroretinol-8 parts, zinc oxide 1-3 part, glycerol 15-25 part, vaseline 20-25 part, lanoline 15-25 part, olive oil 8-12 part, azone 2-4 part.
The unguentum of this treatment dermatitis, its preferred each active component is made up of the raw material of following parts by weight:
Flos Lonicerae 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, the Radix Angelicae Dahuricae 15 parts, 15 parts, soil melon root powder, Calamina 20 parts, Aloe 15 parts, Borneolum Syntheticum 5 parts, Flos Chrysanthemi Indici 12 parts, Fructus Forsythiae 6 parts, Radix Sophorae Flavescentis 5 parts, Radix Salviae Miltiorrhizae 8 parts, Bombyx Batryticatus 8 parts, Rhizoma Cimicifugae 8 parts, 4 parts, Folium Mori, Fructus Atriplicis Sibiricae 6 parts, Radix Saposhnikoviae 15 parts, Periostracum Cicadae 20 parts;
Also comprise the adjuvant of following parts by weight: VITAMIN B15 part, vitamin B2 5 parts, vitamin C 5 parts, vitamin E 5 parts, vitamin A 5 parts, zinc oxide 1.5 parts, glycerol 20 parts, 23.5 parts, vaseline, lanoline 20 parts, 10 parts, olive oil, azone 3 parts.
The preparation method of the unguentum of this treatment dermatitis, adopts following steps preparation:
A, the Flos Lonicerae of getting above-mentioned parts by weight, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, soil melon root powder, Calamina, Aloe, Flos Chrysanthemi Indici, Fructus Forsythiae, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae, Bombyx Batryticatus, Rhizoma Cimicifugae, Folium Mori, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, Periostracum Cicadae mixing, machinery shatters into 10-20 order level micropowder;
B, the micropowder that step a pulverizes is placed in percolator, constantly adds 75% alcoholic solution and carry out percolation, collect the micropowder after leachate and percolation, for subsequent use, the weight of the total alcoholic solution added be the 4-8 of micropowder weight doubly;
C, by after step b percolation micropowder take out dry, continue to be crushed to 200-400 order or nanoscale fine powder;
D, the leachate of step b is evaporated to without ethanol taste, reclaims ethanol, obtain concentrated solution, then mix with the fine powder of step c and stir evenly;
E, get the adjuvant of above-mentioned parts by weight: vitamin B1, vitamin B2, vitamin C, vitamin E, vitamin A, zinc oxide, glycerol, vaseline, lanoline, olive oil and azone, mix and stir evenly;
F, by the mixing of the mixed material of steps d and step e, add the Borneolum Syntheticum of above-mentioned parts by weight, the vortex mixer being placed in 18000-20000rmp/min mixes to ointment shape, to obtain final product.
The present invention treats the usage and dosage of the unguentum of dermatitis: before use, cleaning skin, by paste application in affected part, smears one deck gently at every turn, smears 3-5 times/day.Smear once particularly important before sleeping night, after generally smearing 6-15 days, recovery from illness.
The pharmaceutical characteristic of each active component of the present invention is as follows:
Flos Lonicerae: nature and flavor are sweet, cold.Gas fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Return lung, stomach, large intestine channel.Function cures mainly: heat-clearing and toxic substances removing.Main epidemic febrile disease heating; Toxic-heat and blood stasis; Carbuncle furuncle; Sore throat and multi-infection disease, have removing toxic substances, antiinflammatory, virus killing, sterilization, antipruritic effect, resisting pathogenic microbes.Flos Lonicerae can dispelling wind-heat, and also kind removing summer-heat blood poison, is applicable to various febrile disease, as fever of the body, dermexanthesis, sends out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, equal Be very effective.
Application: the title that Flos Lonicerae has from ancient times " panacea of infections section ".Be described as the good medicine protecting the moon, removing heat from blood, heat-clearing and toxic substances removing.Kind removing summer-heat blood poison, for various for skin ulcer, carbuncle, furuncle and phyma, is the heat and toxic materials clearing away medicine that surgery is conventional.Have and strengthen immunity, the function that strengthens the defense effect: be antiinflammatory, antipyretic.Promote the release of adrenocortical hormone, have obvious inhibitory action to inflammation.Also can be used for carbuncle furunculosis, removing toxic substances and promoting subsidence of swelling effect.For carbuncle furuncle poison, congestion and swelling pain, no matter burst pus or routed pus person, uses Flos Lonicerae all can work.
The Pseudobulbus Bletillae (Rhizoma Bletillae): nature and flavor: bitter sweet, cool.Enter lung meridian.Function cures mainly: tonifying the lung, hemostasis, detumescence, granulation promoting, sore.Control lung and hinder hemoptysis, epistaxis, incised wound is hemorrhage, swollen ulcer drug, canker sores, and soup fire is burnt, rhagadia manus et pedis.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature; Return lung, stomach, large intestine channel; Fragrance rises loose; There is expelling pathogenic wind from the body surface, dispersing cold for relieving pain, removing dampness clearing the nasal passage, effect of detumescence and apocenosis and effect.
Soil melon root powder: meridian distribution of property and flavor: bitter in the mouth, cold in nature, returns spleen, stomach warp, containing enriching the Multiple components such as fatty acid, Kaempferitrin, aminoacid, carotene, choline.Effect: there is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, effect of promoting the circulation of blood removing blood stasis with potent drugs.
Calamina: nature and flavor: sweet, flat, returns stomach warp.Function cures mainly: removing nebula is moved back red, receives warm sore.Control cataract, marginal blepharitis eye, ulcer being unable to heal, skin eczema.Effect: removing toxic substances improving acuity of vision and removing nebula, the antipruritic sore of removing dampness.
Aloe: nature and flavor: bitter, cold.Return liver, stomach, large intestine channel.Function cures mainly: removing heat from the liver, relieving constipation.For constipation, infantile malnutrition, infantile convulsion; External treatment exudative dermatitis.
Borneolum Syntheticum: meridian distribution of property and flavor: pungent, bitter, is slightly cold; GUIXIN, liver, lung meridian; Effect: promote drug absorption.Promote Transdermal absorption.Transdermal enhancer, can promote drugs through skin mucosa, promote external used medicine Transdermal absorption.Have one's ideas straightened out, antibacterial, antiinflammatory, analgesic activity.Increase granulation tissue structure and reepithelialization, repair mucocutaneous, the acceleration that enhances metabolism completes.
Flos Chrysanthemi Indici: nature and flavor: toil is cool.Enter lung, liver.Function cures mainly: wind and heat dispersing, subduing swelling and detoxicating.Control anemopyretic cold, pneumonia, diphtheria, gastroenteritis: hypertension, furuncle, carbuncle, aphtha, erysipelas, eczema, epidemic blisters.Pharmacological evaluation proves, Flos Chrysanthemi Indici is natural " antibiotics ", can suppress and kill tens of kinds of antibacterials.Therefore, various inflammation inside and outside treatment human body is widely used in.When comedo is red and swollen from the beginning of appearance, wash face with Flos Chrysanthemi Indici, can controls local inflammation rapidly, prevent the pigmentation caused by comedo.
Fructus Forsythiae: nature and flavor: bitter, cool.Enter the heart, liver, gallbladder meridian.Heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Function cures mainly: heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Fructus Forsythiae antimicrobial spectrum is very wide, has obvious antiinflammatory action, can promote the formation of inflammatory barrier, reduces capillary permeability, reduces inflammatory exudation, eliminates the local redness that comedo causes.There is certain inhibitory action to smegma, reduce skin excess oiliness, oily skin is improved to effect of skin quality.Fructus Forsythiae can protect normal skin, reduces the generation of comedo and folliculitis.
Radix Sophorae Flavescentis: nature and flavor: bitter, cold.Enter liver, kidney, large intestine, small intestine meridian.Radix Sophorae Flavescentis heat clearing away, pathogenic fire purging, removing toxic substances, damp eliminating, itching-relieving efficacies are obvious, to from the beginning of comedo can eliminate redness.Can also suppress hypersteatosis, reduce sebum alluvial and form acne, keeping skin smooth finish, is one of key agents preventing comedo.
Radix Salviae Miltiorrhizae: nature and flavor: bitter, tepor.Enter the heart, Liver Channel.Blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind, evacuation of pus, pain relieving.Control angina pectoris, menoxenia, dysmenorrhea, amenorrhea, metrorrhagia leukorrhagia, lump in the abdomen, gathers, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.Radix Salviae Miltiorrhizae is improved blood circulation, suppresses the growth and breeding of propionibacterium acnes in hair follicle, controls comedo and occurs; In addition, before feminine menstrual is risen, in body, androgen increases, and stimulates smegma vigorous, easily raw acne, and Radix Salviae Miltiorrhizae can suppress androgen in body, reduces sebum secretion, and comedo appears in prevention " particular time ".
Bombyx Batryticatus: nature and flavor: Xin Xian, flat.Enter liver, lung, stomach warp.Expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Control apoplectic aphasia, infantile convulsion, wind syndrome of head, acute throat trouble.Sore throat, scrofula tuberculosis.Wind skin ulcer urticaria, erysipelas, mastitis.Allly affect beautiful person because depression of liver-QI causes the smooth or phlegm-heat internal-node of QI and blood and commonly use it." Bencao Jingshu " is called: " lung governing skin and hair, and ailment said due to cold or exposure visitor, is then complexion not smooth, pungent temperature people lung, all wind of peeling skin, therefore it is black to go out? and all skin ulcer cicatrixs are also ".As, just there is this medicine the seven white the insides of son.
Rhizoma Cimicifugae: nature and flavor: sweet pungent micro-hardship is cool.Return lung, spleen, stomach, large intestine channel.Deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome sends out speckle; Proctoptosis, uterine prolapse.
Folium Mori: nature and flavor: bitter sweet, cold.Folium Mori are good at loose wind heat and eliminating the pathogens from the lung is hot, not only can be used for the conjunctival congestion photophobia that wind heat causes, and can clearing away liver-fire, and effective in cure to the conjunctival congestion and swelling pain of flaming up of liver-fire, to controlling, dark brown speckle is effective.Containing various active compositions such as flavone compound, volatile oil, aminoacid and polysaccharides of Folium Mori in Folium Mori.Folium Mori contain the various trace elements of flavonoid glycoside, phenols, aminoacid, organic acid, carotene, vitamin B1 and needed by human body.
Fructus Atriplicis Sibiricae: acrid in the mouth, hardship, slightly warm in nature, master enters Liver Channel.Dispersing the stagnated live-QI to relieve the stagnation of QI, circulation of qi promoting removing blood stasis.All depression of liver-QI, the smooth caused complexion of QI and blood is dim, furuncle or eyes illness, all can use this medicine, more multiplex in beauty treatment side.
Radix Saposhnikoviae: acrid in the mouth, warm in nature, Gan Buhuan is not high, and property is not only dispersed but also can win wet.All can use for the illness because of the women's head-ornaments caused by wind and cold, rheumatism, pathogenic wind-warm and the whole body, be one of medicine that in beauty treatment side, the frequency of occurrences is the highest.
Periostracum Cicadae: sweet in the mouth, cold in nature, enter lung, Liver Channel.Quality is very light, frivolously should fall apart, heat clearing away cold in nature again, thus in the side such as, eczema, acne rosacea swollen in treatment Head And Face skin ulcer, mainly with dispelling wind pathogens, loose clear interior-heat of holding concurrently, can be antipruritic, again can nebula removing.So often use this in U.S. eye, itching-stopping prescription.
The adjuvants such as vitamin B1, vitamin B2, vitamin C, vitamin E, vitamin A, zinc oxide, glycerol, vaseline, lanoline, olive oil, azone are added in the above-mentioned active component of this treatment dermatitis unguentum, effect that is moist, that repair can be had to the skin at dermatitis position, the sterilization of medicament, antiseptic property can be strengthened, be more conducive to plaster products molding.Vitamin ingredients can strengthen speckle dispelling, the anti-acne effect of unguentum to a certain extent.The effect for the treatment of in the unguentum of dermatitis in the present invention of each composition is as follows above:
Vitamin B1: effect: the necessary material of skin histology, promotes normal skin tissue's restore funcitons.
Vitamin B2: effect: participate in biological oxidation and energy metabolism in body, relevant with the metabolism of carbohydrate, protein, nucleic acid and fat, the utilization rate of human body to protein can be improved, enhancing development, safeguard the integrity of skin and cell membrane.There is the function of protection skin follicle mucosa and sebaceous gland.
Vitamin C: effect: vitamin C is that antibody and collagen are formed, tissue repairing's (comprising some redox), the metabolism of phenylalanine, tyrosine, folic acid, the utilization of ferrum, carbohydrate, the synthesis of fat, protein, maintains immunologic function, hydroxylation and hydroxytryptamine, keep the complete of blood vessel, promote that the institutes such as nonheme iron absorption are required.
Vitamin E: effect: Wheat Protein.Capillary of skin resistance can be strengthened, and maintain normal permeability, improve blood circulation and adjustment reproductive function, anti-aging effects etc.
Vitamin A: effect: growth promoting effects and reproduction, contributes to protecting epidermis, and mucosa is not by bacterial infestation.
Zinc oxide: effect: convergence and certain sterilizing ability.
Glycerol: effect: have outside moisturizing, humectation function, also has high activity, antioxidation, short alcoholization.
Vaseline (in vain): effect: keep skin wet, makes the skin histology of wound location keep optimum state, accelerates the repair ability of skin self.In addition, vaseline does not have sterilizing ability, and it only blocks from the antibacterial in air and contact skin, thus reduces the probability of infection.
Lanoline: effect: moistness material.Drying or rough skin because lacking natural moisture can be made to soften and be restored.It is by postponing, instead of stops moisture to maintain the common water content of skin through epidermal area completely.
Olive oil: effect: anti-inflammation, short absorption, blood circulation promoting, nourishing effect.
Azone: effect: penetrating agent.
Above composition is prepared into unguentum after processing allotment, be applicable to acute, chronic and allergic dermatitis, effectively can alleviate and remove the various discomfort such as pruritus, long pox that dermatitis causes to patient, to severe skin disease such as various dermatitis, eczema, impetigo, there is good therapeutical effect, pruritus can be eliminated, dispel small pox, there is spot-removal function simultaneously.This product is not containing hormone, and effective ingredient energy rapid osmotic absorbs, and reaches effect of rapid relief of symptoms, ensures that disease is cured substantially or recurrent interval time extends.
The unguentum of this treatment dermatitis, by suitably being coordinated by multi-medicament, utilizes the collaborative or resistant function that it is mutual, and compatibility goes out better to play drug effect and the special unguentum for dermatitis, lastingly evident in efficacy.Flos Lonicerae, Aloe, Rhizoma Cimicifugae, Periostracum Cicadae are cold in nature, there is the merit of clearing away heat and cooling blood, removing toxic substances, rash, coordinate the Pseudobulbus Bletillae (Rhizoma Bletillae), soil melon root powder, Folium Mori, there is effect of heat-clearing and toxic substances removing, antiinflammatory, sterilization, antagonism heat in blood poison is contained, prevent pathological changes and the state of an illness aggravation of inflammation, slow down the various discomforts such as pruritus, remove pox scar pox print; Soil melon root powder is owing to containing the abundant Multiple components such as fatty acid, Kaempferitrin, aminoacid, carotene, choline, its heat-clearing and toxic substances removing can not only be played, dispersing swelling and dissipating binds, the therapeutic efficiency of promoting the circulation of blood removing blood stasis with potent drugs, the absorption of each nutrient of dermatitis patients can also be supplemented, promote the health of body, enhancing human body immunity power; Radix Angelicae Dahuricae removing dampness, dispersing cold for relieving pain, coordinate Calamina, Radix Sophorae Flavescentis, can the antipruritic sore of removing dampness, skin expansion blood capillary, reducing swelling and alleviating pain, and the acceleration that enhances metabolism completes; Flos Chrysanthemi Indici, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae fall apart blood blood stasis removing, subduing swelling and relieving pain, coordinate Fructus Forsythiae, can reparation, dredging the meridian be realized to eczema position, improve microcirculation and capillary permeability targetedly, alleviate and ooze out and inflammatory reaction, promote wound surface inflammatory to absorb and granulation tissue growth, controls local inflammation, keep skin smoothly bright and clean, the pox that disappears acne removing prints; Borneolum Syntheticum, the Radix Angelicae Dahuricae, Fructus Forsythiae are arranged in pairs or groups mutually, can not only sensiblely dehumidify, and also can promote drugs through skin mucosa, promote external used medicine Transdermal absorption; Fructus Atriplicis Sibiricae, Radix Saposhnikoviae have the use for the treatment of and improvement to facial disease disease, obscure to complexion, facial inflammation, speckle have reparation and therapeutical effect, are also common medicines in beauty treatment side.Owing to wherein with the addition of vitamin B1, B2, vitamin C, vitamin E and vitamin A, while treatment, skin tissue recovering can be promoted further, improve blood circulation, enhance metabolism, enhancing human body immunity power; The pigmentation at dermatitis position can also be prevented simultaneously, reduce growth and the diffusion of speckle.The unguentum of this treatment dermatitis breaches western medical treatment limitation, can QI and blood regulating to greatest extent, improve blood circulation, promote and adjust the immune function of body, transfer the resistance against diseases of human body inherence, the balance of adjustment body and external environment, and regulate the dynamic equilibrium of human body, make up lung, spleen on the whole, damage of suffering from a deficiency of the kidney, improve physical function, thus reach the object of cure diseases.Above medicine cooperatively interacts, Comprehensive Treatment, can play the effect of removing toxic substances and promoting subsidence of swelling, loose wind heat clearing away, removing obstruction in the collateral to relieve pain, and the meridians of dredging diseased region, enhance metabolism, and recover the normal function of diseased region, plays specimen and to hold concurrently the effect of system.
The unguentum for the treatment of dermatitis of the present invention is according to Chinese medicine compatibility theory, in conjunction with clinical empirical summary, obtain through repetition test, preparation technology is simple, easy to operate, have the effects such as removing dampness is antipruritic, expelling wind and clearing away heat, removing toxic substances and promoting subsidence of swelling, removing acne and freckle, have good curative effect to dermatitis such as infantile eczema, autosensitization eczema, infectious eczematoid dermatitis, curative effect is short, prove effective rapidly, effect is strong, and nonirritant is safe and reliable, fundamentally can treat dermatitis, played the useful effect for the treatment of both the principal and secondary aspects of a disease, without recurrence or relapse rate low, have no side effect; Use after making unguentum and carry convenient, also further increasing availability and the curative effect of each ingredient.
This strain ointment, the not super required standard of content, be therefore applicable to the various age, all kinds patient, using method is easy, short treating period, cures fast, without any side effects, can carry with.
(4) detailed description of the invention
Below in conjunction with embodiment, the invention will be further described, but the present invention is not limited thereto.
Embodiment 1:
The unguentum of this treatment dermatitis, its active component is made up of the raw material of following weight:
Flos Lonicerae 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Radix Angelicae Dahuricae 15g, soil melon root powder 15g, Calamina 20g, Aloe 15g, Borneolum Syntheticum 5g, Flos Chrysanthemi Indici 12g, Fructus Forsythiae 6g, Radix Sophorae Flavescentis 5g, Radix Salviae Miltiorrhizae 8g, Bombyx Batryticatus 8g, Rhizoma Cimicifugae 8g, Folium Mori 4g, Fructus Atriplicis Sibiricae 6g, Radix Saposhnikoviae 15g, Periostracum Cicadae 20g;
Also comprise the adjuvant of following weight: VITAMIN B15 g, vitamin B2 5g, vitamin C 5g, vitamin E 5g, vitamin A 5g, zinc oxide 1.5g, glycerol 20g, vaseline 23.5g, lanoline 20g, olive oil 10g, azone 3g.
The preparation method of the unguentum of this treatment dermatitis, adopts following steps:
A, the Flos Lonicerae of getting above-mentioned weight, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, soil melon root powder, Calamina, Aloe, Flos Chrysanthemi Indici, Fructus Forsythiae, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae, Bombyx Batryticatus, Rhizoma Cimicifugae, Folium Mori, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, Periostracum Cicadae mixing, machinery shatters into 10 order level micropowders;
B, the micropowder that step a pulverizes is placed in percolator, constantly adds 75% alcoholic solution and carry out percolation, collect the micropowder after leachate and percolation, for subsequent use, the weight of the total alcoholic solution added be the 4-of micropowder weight doubly;
C, by after step b percolation micropowder take out dry, continue to be crushed to 400 orders or nanoscale fine powder;
D, the leachate of step b is evaporated to without ethanol taste, reclaims ethanol, obtain concentrated solution, then mix with the fine powder of step c and stir evenly;
E, get the adjuvant of above-mentioned weight: vitamin B1, vitamin B2, vitamin C, vitamin E, vitamin A, zinc oxide, glycerol, vaseline, lanoline, olive oil and azone, mix and stir evenly;
F, mixed and add the Borneolum Syntheticum of above-mentioned weight by the mixed material of steps d and step e, the vortex mixer being placed in 18000rmp/min mixes to ointment shape, to obtain final product.
Usage and dosage: before use, cleaning skin, by paste application in affected part, smears one deck gently at every turn, smears 3-5 times/day.Smear once particularly important before sleeping night, after generally smearing 6-15 days, recovery from illness.
Embodiment 2:
The unguentum of this treatment dermatitis, its active component is made up of the raw material of following weight:
Flos Lonicerae 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 10g, Radix Angelicae Dahuricae 10g, soil melon root powder 10g, Calamina 15g, Aloe 10g, Borneolum Syntheticum 4g, Flos Chrysanthemi Indici 10g, Fructus Forsythiae 4g, Radix Sophorae Flavescentis 4g, Radix Salviae Miltiorrhizae 5g, Bombyx Batryticatus 5g, Rhizoma Cimicifugae 5g, Folium Mori 2g, Fructus Atriplicis Sibiricae 4g, Radix Saposhnikoviae 10g, Periostracum Cicadae 15g;
Also comprise the adjuvant of following weight: vitamin B12 g, vitamin B2 2g, Catergen g, vitamin E2 g, dehydroretinol g, zinc oxide 1g, glycerol 15g, vaseline 20g, lanoline 15g, olive oil 8g, azone 4g.
The preparation method of the unguentum of this treatment dermatitis, adopts following steps:
A, the Flos Lonicerae of getting above-mentioned weight, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, soil melon root powder, Calamina, Aloe, Flos Chrysanthemi Indici, Fructus Forsythiae, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae, Bombyx Batryticatus, Rhizoma Cimicifugae, Folium Mori, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, Periostracum Cicadae mixing, machinery shatters into 20 order level micropowders;
B, be placed in percolator by the micropowder that step a pulverizes, constantly add 75% alcoholic solution and carry out percolation, collect the micropowder after leachate and percolation, for subsequent use, the weight of the total alcoholic solution added is 8 times of micropowder weight;
C, by after step b percolation micropowder take out dry, continue to be crushed to 200 orders or nanoscale fine powder;
D, the leachate of step b is evaporated to without ethanol taste, reclaims ethanol, obtain concentrated solution, then mix with the fine powder of step c and stir evenly;
E, get the adjuvant of above-mentioned weight: vitamin B1, vitamin B2, vitamin C, vitamin E, vitamin A, zinc oxide, glycerol, vaseline, lanoline, olive oil and azone, mix and stir evenly;
F, mixed and add the Borneolum Syntheticum of above-mentioned weight by the mixed material of steps d and step e, the vortex mixer being placed in 20000rmp/min mixes to ointment shape, to obtain final product.
Usage and dosage, with embodiment 1, no longer describes in detail herein.
Embodiment 3:
The unguentum of this treatment dermatitis, its active component is made up of the raw material of following weight:
Flos Lonicerae 20g, Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Radix Angelicae Dahuricae 20g, soil melon root powder 20g, Calamina 25g, Aloe 20g, Borneolum Syntheticum 7g, Flos Chrysanthemi Indici 15g, Fructus Forsythiae 8g, Radix Sophorae Flavescentis 6g, Radix Salviae Miltiorrhizae 10g, Bombyx Batryticatus 10g, Rhizoma Cimicifugae 10g, Folium Mori 6g, Fructus Atriplicis Sibiricae 8g, Radix Saposhnikoviae 20g, Periostracum Cicadae 25g;
Also comprise the adjuvant of following weight: vitamin B1 8g, vitamin B2 8g, vitamin C 8g, vitamin E 8g, vitamin A 8g, zinc oxide 3g, glycerol 25g, vaseline 25g, lanoline 25g, olive oil 12g, azone 4g.
The preparation method of the unguentum of this treatment dermatitis, adopts following steps:
A, the Flos Lonicerae of getting above-mentioned weight, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, soil melon root powder, Calamina, Aloe, Flos Chrysanthemi Indici, Fructus Forsythiae, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae, Bombyx Batryticatus, Rhizoma Cimicifugae, Folium Mori, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, Periostracum Cicadae mixing, machinery shatters into 10 order level micropowders;
B, be placed in percolator by the micropowder that step a pulverizes, constantly add 75% alcoholic solution and carry out percolation, collect the micropowder after leachate and percolation, for subsequent use, the weight of the total alcoholic solution added is 6 times of micropowder weight;
C, by after step b percolation micropowder take out dry, continue to be crushed to 300 orders or nanoscale fine powder;
D, the leachate of step b is evaporated to without ethanol taste, reclaims ethanol, obtain concentrated solution, then mix with the fine powder of step c and stir evenly;
E, get the adjuvant of above-mentioned weight: vitamin B1, vitamin B2, vitamin C, vitamin E, vitamin A, zinc oxide, glycerol, vaseline, lanoline, olive oil and azone, mix and stir evenly;
F, mixed and add the Borneolum Syntheticum of above-mentioned weight by the mixed material of steps d and step e, the vortex mixer being placed in 20000rmp/min mixes to ointment shape, to obtain final product.
Usage and dosage, with embodiment 1, no longer describes in detail herein.
Embodiment 4:
The unguentum of this treatment dermatitis, its active component is made up of the raw material of following weight:
Flos Lonicerae 12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 12g, Radix Angelicae Dahuricae 12g, soil melon root powder 12g, Calamina 18g, Aloe 12g, Borneolum Syntheticum 4g, Flos Chrysanthemi Indici 11g, Fructus Forsythiae 5g, Radix Sophorae Flavescentis 4g, Radix Salviae Miltiorrhizae 6g, Bombyx Batryticatus 6g, Rhizoma Cimicifugae 6g, Folium Mori 3g, Fructus Atriplicis Sibiricae 5g, Radix Saposhnikoviae 12g, Periostracum Cicadae 17g;
Also comprise the adjuvant of following weight: orotic acid g, vitamin B2 3g, vitamin C 3g, vitamin E 3g, 3-Hydroxyretinol g, zinc oxide 2g, glycerol 18g, vaseline 22g, lanoline 18g, olive oil 9g, azone 2g.
The preparation method of the unguentum of this treatment dermatitis, adopts following steps:
A, the Flos Lonicerae of getting above-mentioned weight, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, soil melon root powder, Calamina, Aloe, Flos Chrysanthemi Indici, Fructus Forsythiae, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae, Bombyx Batryticatus, Rhizoma Cimicifugae, Folium Mori, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, Periostracum Cicadae mixing, machinery shatters into 10 order level micropowders;
B, be placed in percolator by the micropowder that step a pulverizes, constantly add 75% alcoholic solution and carry out percolation, collect the micropowder after leachate and percolation, for subsequent use, the weight of the total alcoholic solution added is 5 times of micropowder weight;
C, by after step b percolation micropowder take out dry, continue to be crushed to 300 orders or nanoscale fine powder;
D, the leachate of step b is evaporated to without ethanol taste, reclaims ethanol, obtain concentrated solution, then mix with the fine powder of step c and stir evenly;
E, get the adjuvant of above-mentioned weight: vitamin B1, vitamin B2, vitamin C, vitamin E, vitamin A, zinc oxide, glycerol, vaseline, lanoline, olive oil and azone, mix and stir evenly;
F, mixed and add the Borneolum Syntheticum of above-mentioned weight by the mixed material of steps d and step e, the vortex mixer being placed in 18000rmp/min mixes to ointment shape, to obtain final product.
Usage and dosage, with embodiment 1, no longer describes in detail herein.
Embodiment 5:
The unguentum of this treatment dermatitis, its active component is made up of the raw material of following weight:
Flos Lonicerae 18g, Pseudobulbus Bletillae (Rhizoma Bletillae) 18g, Radix Angelicae Dahuricae 18g, soil melon root powder 18g, Calamina 22g, Aloe 18g, Borneolum Syntheticum 6g, Flos Chrysanthemi Indici 14g, Fructus Forsythiae 7g, Radix Sophorae Flavescentis 5g, Radix Salviae Miltiorrhizae 9g, Bombyx Batryticatus 9g, Rhizoma Cimicifugae 9g, Folium Mori 5g, Fructus Atriplicis Sibiricae 7g, Radix Saposhnikoviae 18g, Periostracum Cicadae 22g;
Also comprise the adjuvant of following weight: vitamin B1 6g, vitamin B2 6g, vitamin C 6g, vitamin E 6g, vitamin A 6g, zinc oxide 3g, glycerol 22g, vaseline 24g, lanoline 22g, olive oil 11g, azone 4g.
The preparation method of the unguentum of this treatment dermatitis, adopts following steps:
A, the Flos Lonicerae of getting above-mentioned weight, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, soil melon root powder, Calamina, Aloe, Flos Chrysanthemi Indici, Fructus Forsythiae, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae, Bombyx Batryticatus, Rhizoma Cimicifugae, Folium Mori, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, Periostracum Cicadae mixing, machinery shatters into 10 order level micropowders;
B, be placed in percolator by the micropowder that step a pulverizes, constantly add 75% alcoholic solution and carry out percolation, collect the micropowder after leachate and percolation, for subsequent use, the weight of the total alcoholic solution added is 7 times of micropowder weight;
C, by after step b percolation micropowder take out dry, continue to be crushed to 400 orders or nanoscale fine powder;
D, the leachate of step b is evaporated to without ethanol taste, reclaims ethanol, obtain concentrated solution, then mix with the fine powder of step c and stir evenly;
E, get the adjuvant of above-mentioned weight: vitamin B1, vitamin B2, vitamin C, vitamin E, vitamin A, zinc oxide, glycerol, vaseline, lanoline, olive oil and azone, mix and stir evenly;
F, mixed and add the Borneolum Syntheticum of above-mentioned weight by the mixed material of steps d and step e, the vortex mixer being placed in 20000rmp/min mixes to ointment shape, to obtain final product.
Usage and dosage, with embodiment 1, no longer describes in detail herein.
Clinical observation:
One, adopt the treatment situation of unguentum to infantile eczema of embodiment of the present invention 1-5 arbitrary treatment dermatitis as follows:
1, choose case history and meet diagnosis infantile eczema.
2, criterion of therapeutical effect:
Recovery from illness: face or the red disappearance of eczema at other positions of health, noresidue vestige, baby cries and screams minimizing;
Take a turn for the better: eczema reduces in a large number, occasionally have fragmentary remaining red point;
Do not heal: symptom is unchanged.
3, Therapeutic Method:
By paste application of the present invention in affected part, smear one deck gently at every turn, smear 3 times/day.Select to smear during baby sleeping, after generally smearing 6-15 days, recovery from illness.
Matched group selects the precious frost (child form) of Huang Um hall board profit to smear, and smears one deck gently at every turn, smears 3 times/day.Select to smear during baby sleeping.
Clinical case history test 100 example, the neonate of course of disease 1-20 days, monthly age 1-2 month, each 50 people for the treatment of group, matched group.Symptom improvement situation after 1 week for the treatment of is as shown in table 1 below:
Group Recovery from illness Take a turn for the better Do not heal Effective percentage %
Treatment group 30 18 2 96
Matched group 19 20 11 78
As can be seen from the above table, two groups of each 50 routine infantile eczema patients, when the paste application treatment carrying out this treatment dermatitis, high for the precious frost of infantile eczema treatment Huang Um hall board profit (child form) curative effect more on the market, and effective percentage is apparently higher than matched group.Followed up a case by regular visits to through one month, treatment group has no recurrence, matched group then in the winter time indoor temperature slightly high (> 25 DEG C) time occur recurrence situation.
Two, adopt the treatment situation of unguentum to adult's eczematoid dermatitis (body sensitivity eczema and infectious eczematoid dermatitis) of embodiment of the present invention 1-5 arbitrary treatment dermatitis as follows:
1, choose case history and meet diagnosis eczematoid dermatitis.
2, criterion of therapeutical effect:
Recovery from illness: the pimple that gregariousness distributes, papulovesicle and vesicle disappear, pruritus disappears, noresidue vestige; Erythema, sepage and incrustation disappear, and pruritus disappears, noresidue vestige; Small pox disappears, pox scar pox print is eliminated; Face speckle shoals; Health is uncomfortable without other;
Take a turn for the better: pimple, papulovesicle and vesicle reduce in a large number, violent pruritus disappears, and occasionally has gargalesthesia, still has a small amount of remaining pimple; Erythema reduces in a large number, without sepage and incrustation; To there being the patient of small pox to have certain acne-removal function, small pox reduces;
Do not heal: symptom is unchanged.
3, Therapeutic Method:
By paste application of the present invention in affected part, smear one deck gently at every turn, smear 3 times/day.Smear before sleeping evening once, after generally smearing 6-15 days, recovery from illness.
Matched group 1 selects QUMIXIN emulsifiable paste to smear, and smears one deck gently at every turn, smears 3 times/day.
Matched group 2 is selected Jiang Shi to defend skin frost and is smeared, and smears one deck gently at every turn, smears 3 times/day.
Clinical case history tests 225 people, each 75 people for the treatment of group, matched group; Course of disease 1-30 days.Symptom improvement situation after 2 weeks for the treatment of is as shown in the table:
Group Recovery from illness Take a turn for the better Do not heal Effective percentage %
Treatment group 45 26 4 94.7
Matched group 1 30 31 14 81.3
Matched group 2 26 33 16 78.6
As can be seen from the above table, three groups of each 75 routine eczematoid dermatitis patients, when the paste application treatment carrying out this treatment dermatitis, treating the Western medicine QUMIXIN emulsifiable paste (matched group 1) of eczematoid dermatitis and Chinese medicine Jiang Shi more on the market, to defend skin frost (matched group 2) curative effect all high, and effective percentage is apparently higher than matched group 1 and matched group 2.Followed up a case by regular visits to through one month, treatment group has no recurrence, and the patient of matched group 1 and matched group 2 all has recurrence to occur.

Claims (3)

1. treat a unguentum for dermatitis, it is characterized in that: its active component is made up of the raw material of following parts by weight:
Flos Lonicerae 10-20 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 part, Radix Angelicae Dahuricae 10-20 part, soil melon root powder 10-20 part, Calamina 15-25 part, Aloe 10-20 part, Borneolum Syntheticum 4-7 part, Flos Chrysanthemi Indici 10-15 part, Fructus Forsythiae 4-8 part, Radix Sophorae Flavescentis 4-6 part, Radix Salviae Miltiorrhizae 5-10 part, Bombyx Batryticatus 5-10 part, Rhizoma Cimicifugae 5-10 part, Folium Mori 2-6 part, Fructus Atriplicis Sibiricae 4-8 part, Radix Saposhnikoviae 10-20 part, Periostracum Cicadae 15-25 part;
Also comprise the adjuvant of following parts by weight: vitamin B12-8 parts, vitamin B2 2-8 part, Catergen-8 parts, vitamin E2-8 parts, dehydroretinol-8 parts, zinc oxide 1-3 part, glycerol 15-25 part, vaseline 20-25 part, lanoline 15-25 part, olive oil 8-12 part, azone 2-4 part.
2. a kind of unguentum for the treatment of dermatitis according to claim 1, is characterized in that: its active component is made up of the raw material of following parts by weight:
Flos Lonicerae 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, the Radix Angelicae Dahuricae 15 parts, 15 parts, soil melon root powder, Calamina 20 parts, Aloe 15 parts, Borneolum Syntheticum 5 parts, Flos Chrysanthemi Indici 12 parts, Fructus Forsythiae 6 parts, Radix Sophorae Flavescentis 5 parts, Radix Salviae Miltiorrhizae 8 parts, Bombyx Batryticatus 8 parts, Rhizoma Cimicifugae 8 parts, 4 parts, Folium Mori, Fructus Atriplicis Sibiricae 6 parts, Radix Saposhnikoviae 15 parts, Periostracum Cicadae 20 parts;
Also comprise the adjuvant of following parts by weight: VITAMIN B15 part, vitamin B2 5 parts, vitamin C 5 parts, vitamin E 5 parts, vitamin A 5 parts, zinc oxide 1.5 parts, glycerol 20 parts, 23.5 parts, vaseline, lanoline 20 parts, 10 parts, olive oil, azone 3 parts.
3. a preparation method for the unguentum for the treatment of dermatitis as claimed in claim 1, is characterized in that: comprise the steps:
A, the Flos Lonicerae of getting above-mentioned parts by weight, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Radix Angelicae Dahuricae, soil melon root powder, Calamina, Aloe, Flos Chrysanthemi Indici, Fructus Forsythiae, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae, Bombyx Batryticatus, Rhizoma Cimicifugae, Folium Mori, Fructus Atriplicis Sibiricae, Radix Saposhnikoviae, Periostracum Cicadae mixing, machinery shatters into 10-20 order level micropowder;
B, the micropowder that step a pulverizes is placed in percolator, constantly adds 75% alcoholic solution and carry out percolation, collect the micropowder after leachate and percolation, for subsequent use, the weight of the total alcoholic solution added be the 4-8 of micropowder weight doubly;
C, by after step b percolation micropowder take out dry, continue to be crushed to 200-400 order or nanoscale fine powder;
D, the leachate of step b is evaporated to without ethanol taste, reclaims ethanol, obtain concentrated solution, then mix with the fine powder of step c and stir evenly;
E, get the adjuvant of above-mentioned parts by weight: vitamin B1, vitamin B2, vitamin C, vitamin E, vitamin A, zinc oxide, glycerol, vaseline, lanoline, olive oil and azone, mix and stir evenly;
F, by the mixing of the mixed material of steps d and step e, add the Borneolum Syntheticum of above-mentioned parts by weight, mix to ointment shape, obtain the unguentum of this treatment dermatitis.
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CN110200901A (en) * 2019-06-14 2019-09-06 贵州省习水县人民医院 A kind of cream preparation that treating subacute eczema and preparation method
CN114452318A (en) * 2022-02-22 2022-05-10 威高(北京)医疗科技有限公司 Anti-inflammatory traditional Chinese medicine composition for sanitary products and preparation method and application thereof

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Publication number Priority date Publication date Assignee Title
CN110200901A (en) * 2019-06-14 2019-09-06 贵州省习水县人民医院 A kind of cream preparation that treating subacute eczema and preparation method
CN114452318A (en) * 2022-02-22 2022-05-10 威高(北京)医疗科技有限公司 Anti-inflammatory traditional Chinese medicine composition for sanitary products and preparation method and application thereof

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