CN105028763A

CN105028763A - Pressure-reducing health tea

Info

Publication number: CN105028763A
Application number: CN201510408955.5A
Authority: CN
Inventors: 不公告发明人
Original assignee: Qingdao Huaren Technology Incubator Co Ltd
Current assignee: Qingdao Huaren Technology Incubator Co Ltd
Priority date: 2015-07-14
Filing date: 2015-07-14
Publication date: 2015-11-11

Abstract

The invention provides a pressure-reducing health tea. The health tea comprises raw materials of Qingdao Laoshan green tea, gen-seng, loranthus parasiticus, rhizoma imperatae, spica prunellae, radix achyranthis bidentatae, celandine, cacumen platycladi, uncaria, common bluebeard herb, tamarisk, cattail pollen, rhizoma corydalis, madder, Zhejiang fritillaria bulb, rhizoma anemarrhenae, spatholobus stem, oyster, and root of veined inula. The pressure-reducing health tea can regulate capillary circulation, release arteriole spasm, harmonize qi and blood, regulate yin and yang, and improve symptom. The side effect is reduced and the compliance of a patient is improved, so that the purpose of preventing and curing hypertension is achieved.

Description

Step-down health preserving tea

Technical field

The present invention relates to health product technical field, particularly relate to a kind of step-down health preserving tea.

Background technology

Tea is the beverage that our people is traditional, so far the history of existing thousands of years.Tea, not still a kind of fabulous thirst relieving beverage, and nutritious, taking out nutrient that (amino acid), fat, carbohydrate, vitamin, mineral matter etc. human body needs simultaneously containing albumen, is also a kind of very effective Chinese medicine.Shennong's Herbal is mentioned: " tea flavour is bitter, people is beneficially thought, the crouching less, make light of one's life by commiting suicide of drink, improving eyesight." Chinese dynasties doctor thinks that tealeaves has a lot of effect in preventing and curing diseases, be summed up and can have ten many aspects, such as clearing heat and detoxicating, help digestion fat-reducing, the dampness removing that reduces phlegm, promote the production of body fluid to quench thirst, benefit of refreshing oneself thinks.Therefore tealeaves is good beverage/food, it is again highly effective medicine.

In tea and dietotherapy, often add the suitable and appropriate Chinese medicine of people again in tea, the effect of existing tea has again effect of Chinese medicine, then the benefit such as diseases prevention and health can be made to strengthen, its application wider, can get twice the result with half the effort, bring out the best in each other." medicinal herb tea " conventional in the dietary therapy of Chinese medicine that Here it is.From broadly, " medicinal herb tea " should comprise four aspects: one is folk prescription, namely uses single tealeaves because tealeaves itself is also Chinese medicine, such as with the tealeaves of old tea tree control ward off urine sick, control with single strong tea diarrhea etc. of suffering from diarrhoea; Two is compounds that Chinese medicine and tealeaves form, and this is the type of " medicinal herb tea " plurality, such as, control the Bazhen tea etc. of the tea period of the day from 11 a.m. to 1 p.m of wind plug flu, nourishing liver and kidney Chinese wolfberry tea, health care.Be all that one, two tastes or number taste Chinese medicine form with tealeaves, due to integration of drinking and medicinal herbs, some Chinese medicine is exactly food, also can claim medicinal herb tea as red date, ginger, Gui Yuan, lotus nut etc. are added in tea; Three is with tea for water, takes Chinese medicine, " Chuanxiong Chatiao San " of such as treatment headache, and be taken after mixing with liquid with green tea, some Chinese patent drug controlling illness in eye also must take with tea; Four is brew with other Chinese medicines (or food) or decoct Tang Daicha, therefore also known as tea-drinking, such as, stops abnormal sweating light wheat tea, and namely light wheat decocts soup simply when tea-drinking clothes, controls hypertension chrysanthemum tea, namely brews simply for tea etc. with chrysanthemum.

Chinese medicine is for tea-drinking and medicinal herb tea, also known as medicinal tea, be finger Chinese herbal medicine and tealeaves adapted, Chinese medicine is China's conventional dosage forms for tea-drinking, be under the guidance of traditional Chinese medical science science, method, prescription, drugs theoretical principle, by dialectical combining with the differentiation of disease, prescription selects medicine and tealeaves (or not containing tealeaves) conjunction system to form.Chinese medicine has been widely used in person in middle and old age's health cultivation and rehabilitation field for tea-drinking.Chinese medicine is light for tea-drinking consumption, should be taken in small doses at short intervals, and mild in medicine property and, harmless stomach Qi, therefore can adhere to for a long time taking, its effect of planning slowly and carefully, with and internal organs, be particularly useful for the treatment of chronic disease and the adjustment of body function.There are some researches show, long-term taking medicinal herb tea, the active ingredient of medicine can be made to maintain higher concentration in vivo, and drug effect is consolidated, it is comparatively lasting to act on.

Essential hypertension (EH), i.e. high blood pressure, is common angiocardiopathy, increases the clinical syndrome for main manifestations with systemic arterial blood pressure continuation.Hypertension has become a kind of common, multiple chronic disease of person in middle and old age, and is difficult to thoroughly radical cure, and the control of high blood pressure is a long-term process, and need to take medicine all the life, this just occurs following problem unavoidably more: one is the compliance problem of patient; Two is financial burden; Three is toxic and side effects of medicine.At present, clinically number of mechanisms medicine Treatment of Hypertension is adopted for hyperpietic, but to cause antihypertensive effect undesirable because of patient compliance and multiple extraneous factor sometimes.

Adopt Chinese medicine medicinal herb tea therapy, can adjust microcirculation, remove arteriolar spasm, the promoting flow of qi and blood, YIN and YANG balance regulating, improves symptom, reduces side effect, improves the compliance of patient, thus plays the object of preventing and treating high blood pressure.

Summary of the invention

Technical problem to be solved by this invention is to provide a kind of step-down health preserving tea, adopts Chinese medicine medicinal herb tea therapy, can adjust microcirculation, remove arteriolar spasm, the promoting flow of qi and blood, YIN and YANG balance regulating, improves symptom, reduce side effect, improve the compliance of patient, thus play the object of preventing and treating high blood pressure.

For solving the problems of the technologies described above, the invention provides a kind of step-down health preserving tea, its raw material comprises Laoshan green tea, ginseng, parasitic loranthus, cogongrass rhizome, selfheal, the root of bidentate achyranthes, greater celandine, cacumen biotae, yncaria stem with hooks, cayropteris incana, strange willow, cattail pollen, corydalis tuber, madder, fritillaria thunbergii, the wind-weed, reticulate millettia, oyster and veined inula root.

Wherein, in described step-down health preserving tea, the weight of each raw material is respectively every 200 _gthe corresponding ginseng 4g ~ 6g of Laoshan green tea, parasitic loranthus 1g ~ 3g, cogongrass rhizome 2g ~ 4g, selfheal 2g ~ 4g, root of bidentate achyranthes 3g ~ 5g, greater celandine 1g ~ 3g, cacumen biotae 2g ~ 4g, yncaria stem with hooks 2g ~ 4g, cayropteris incana 1g ~ 3g, strange willow 2g ~ 4g, cattail pollen 2g ~ 4g, corydalis tuber 1g ~ 3g, madder 2g ~ 4g, fritillaria thunbergii 1g ~ 3g, wind-weed 2g ~ 4g, reticulate millettia 3g ~ 5g, oyster 2g ~ 4g and veined inula root 1g ~ 3g.

Wherein, in described step-down health preserving tea, the weight of each raw material is respectively the corresponding ginseng 5g of every 200g Laoshan green tea, parasitic loranthus 2g, cogongrass rhizome 3g, selfheal 3g, root of bidentate achyranthes 4g, greater celandine 2g, cacumen biotae 3g, yncaria stem with hooks 3g, cayropteris incana 2g, strange willow 3g, cattail pollen 3g, corydalis tuber 2g, madder 3g, fritillaria thunbergii 2g, wind-weed 3g, reticulate millettia 4g, oyster 3g and veined inula root 2g.

Present invention also offers the preparation method of above-mentioned step-down health preserving tea, specifically comprise:

The first step, the process of Laoshan green tea;

Second step, the preparation of Chinese medicine concoction;

3rd step, Laoshan green tea after process is joined in the middle of Chinese medicine concoction prepared by second step, stirs, adopt the warm water of 50 DEG C ~ 60 DEG C to boil 20min ~ 40min subsequently, tealeaves after boiling is pulled out, puts into dryer and carries out oven dry and obtain step-down health preserving tea.

Wherein, in the described first step, the process of Laoshan green tea is specially tealeaves to be placed in food steamer further and evenly spreads out, and food steamer is put into boiler boiling 20min ~ 30min, boiling is complete, is tedded by tealeaves under sunlight, allows sunlight carry out nature dehumidifier to tealeaves, described tealeaves dehumidifier reaches 60% ~ 80%, tealeaves after dehumidifier is put into kneading machine knead, the time of kneading is 10min ~ 15min, obtains the tealeaves after process.

Wherein, described second step is specially each Chinese medicine material composition further and shreds respectively, the product of chopping mixes according to above-mentioned weight portion, obtain mixture, add the water relative to this mixture 3 ~ 5 times of quality, soak 1 hour, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, filter residue adds the water relative to mixture 2 ~ 4 times of quality again, is heated to boiling, decocts 2 ~ 3 hours, decoction liquor is filtered, the filtered fluid mixing of twice, reduced pressure concentration, obtaining crude drug concentration is the concoction of 0.3g/ml.

Beneficial effect of the present invention:

Step-down health preserving tea provided by the invention, adopts Chinese medicine medicinal herb tea therapy to prevent and treat hypertension, can adjust microcirculation, remove arteriolar spasm, the promoting flow of qi and blood, YIN and YANG balance regulating, improves symptom, reduce side effect, improve the compliance of patient, thus play the object of preventing and treating high blood pressure.

Detailed description of the invention

High blood pressure is modern medicine noun, and record without hyperbarism name in traditional Chinese medical science historical book, the description relevant with this disease, generally belongs to the traditional Chinese medical science " dizzy ", " headache " category, and closely related with " palpitaition ", " palpitation ", " apoplexy ".Traditional Chinese medicine thinks that high blood pressure system is relevant with pathological factors such as " wind, fire, phlegm, the stasis of blood, void ", mainly due to disorder of emotion, eating and drinking without temperance, work and rest excessively, insufficiency of natural endowment and physique contains factors such as partially declining partially, cause viscera imbalance between YIN and YANG, qi depression to blood stasis, disturbance in ascending and descending, raw in wind fire, the phlegm stasis of blood is handed over resistance and falls ill.

Containing a large amount of Tea Polyphenols in green tea, tea polyphenols material has multiple phenolic hydroxyl group, is suppressed the oxidation of cholesterol by the strong anti-oxidative activity of self, makes thing formation volume minimizing of becoming sour, and suppresses lipid to deposit on vascular wall.Stop the oxidation of unrighted acid in food on the other hand, thus decrease the content of cholesterol in serum and keep lipid in the dynamic equilibrium of the normal turnover of arterial wall, there is the antiatherogenic effect of lipopenicillinase.The anti-freezing of Tea Polyphenols, promote fibrinolytic and platelet aggregation-against, hypotensive, lipopenicillinase, prevent and treat atherosclerotic, may be stronger award electronic capability owing to having, easily be combined with zymoprotein, compound can be formed with fibrin ferment, fibrinogen is not made to become fibrin, simultaneously, catechin can also by the oxidation of self, suppress cholesterol and unsaturated fatty oxidation, this not only reduces cholesterol and oxidation product thereof in eparterial deposition, and be conducive to unsaturated fat to the running of cholesterol and scavenging action.In addition catechin can also reduce cohesion significantly by artery facial mask effect, reduces the permeability of table cell in artery, stops the formation of thrombus.

Based on this, the invention provides a kind of step-down health preserving tea, its raw material comprises Laoshan green tea, ginseng, parasitic loranthus, cogongrass rhizome, selfheal, the root of bidentate achyranthes, greater celandine, cacumen biotae, yncaria stem with hooks, cayropteris incana, strange willow, cattail pollen, corydalis tuber, madder, fritillaria thunbergii, the wind-weed, reticulate millettia, oyster and veined inula root.

Further preferably, described step-down health preserving tea is only prepared from by above-mentioned raw materials.

Step-down health preserving tea traditional Chinese medicine ingredients provided by the invention is with nourishing liver and kidney, calming the liver, promoting blood circulation and removing obstruction in channels is principle, ginseng reinforces vital energy, using tonifying Qi reinforcing lungs, parasitic loranthus is nourishing liver and kidney, cogongrass rhizome cooling blood and hemostasis, have and reduce blood pressure, lipopenicillinase, lipopenicillinase, improve the effects such as cardiovascular and cerebrovascular circulation, selfheal relieves inflammation or internal heat detumescence, there is vasodilator, the effect reduced blood pressure, the root of bidentate achyranthes is ensuringd proper downward flow of the blood, energy hemangiectasis, reduce blood viscosity and anti-freezing, effect for reducing fat, greater celandine is logical superintends and directs spasmolysis, CBF is strengthened, cacumen biotae cooling blood and hemostasis, there is reduction peripheral vascular resistance, thus reduce blood pressure, increase cerebral blood flow (CBF), improve the effects such as myocardial ischemia, yncaria stem with hooks is calming the liver, by stimulating cardiovascular system receptor, by vagus nerve and hole nerve, inhibit vasomotor center to reflectivity, peripheral vascular is expanded and step-down, cayropteris incana dehumidifying is dispelled the stasis of blood, vascular smooth muscle contraction can be suppressed, alleviating vascular spasm, increase vasopermeability, remove vascular wall aliphatic salt, alleviate blood vessel vitreous degeneration, Chinese tamarisk expelling wind to resolve the exterior, cattail pollen, corydalis tuber promoting blood circulation, significantly can improve CBF by hemangiectasis, improve circulation thickness obstacle and antithrombotic, madder is promoting blood circulation and removing obstruction in channels, the step-down of direct expansion peripheral vessel is lasting, fritillaria thunbergii clearing heat and eliminating phlegm, eliminate phlegm for resuscitation, the wind-weed is nourshing Yin and drynsessmoistening prescription, reticulate millettia is hypotensive, cholesterol levels is made comparatively fast to drop to normally, oyster is calming the liver, peripheral vascular resistance can be reduced, thus reduce blood pressure, increase cerebral blood flow (CBF), improve the effects such as myocardial ischemia.

Each bulk drug pharmacology is as follows:

Ginseng: sweet, the micro-hardship of taste, slightly warm in nature, enter the heart, lung, the spleen channel, reinforce vital energy, using tonifying Qi reinforcing lungs, promote the production of body fluid to quench thirst, to calm the nerves the effects such as intelligence development, both for emergency treatment of collapse holds up good dose of danger, also for treating the first key medicine of consumptive disease internal injury, the card of all insufficiency of vital energy and blood all can be applied, cure mainly that internal lesion caused by overexertion is deficient, food less, burnout, gastric disorder causing nausea tells food, stool lingering diarrhea, void cough that syndrome characterized by dyspnea, spontaneous perspiration are cruelly de-, palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition, quench one's thirst, woman uterine bleeding, children's's frightened and void card such as again for a long time slowly.

Parasitic loranthus: bitter, sweet, property is put down, and enters liver, kidney channel, have the effect of filling liver kidney, strengthening the bones and muscles, wines used as antirheumatic, antiabortive unit, for the soreness of waist pain caused by kidney deficiency and liver, muscles and bones impotence is soft, the foot and knee being feeble, kidney deficiency and liver, essence and blood void is lost, the fetal irritability of liability to be abortion, the cards such as waist abdomen pain.

Cogongrass rhizome: taste is sweet, cold in nature, enter lung, stomach, urinary bladder channel, have the effect of cooling blood and hemostasis, reducing fever and causing diuresis, be mainly used in haematemesis, hemoptysis that lung stomach has accumulated heat; Damp invasion of lower energizer pents up the hematuria of bladder; Pyreticosis polydipsia draws drink; Gastropyretic vomiting; The cards such as jaundice with damp-heat pathogen.

Selfheal: bitter, pungent, cold in nature, enter liver, gallbladder channel, have and relieve inflammation or internal heat, improving eyesight, dissipating bind, effect of detumescence, cures mainly red eye, swell pain, and order pearl nyctalgia, has a headache dizzy, scrofula, and goiter and tumor, swells and ache; Thyroid Gland Swell, scrofula, the proliferation of mammary gland, the cards such as hypertension, hyperglycaemia, high fat of blood and high blood are sticky.

The root of bidentate achyranthes: bitter, acid, property is put down, and enters liver, kidney channel, there is filling liver kidney, strengthening the bones and muscles, activating blood to promote menstruation, ignite that (blood) is descending, effect of inducing diuresis for treating strangurtia, treatment soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhoea, postpartum abdominal pain due to blood stasis, abdominal mass, placenta retension, heat is drenched, blood drenches, traumatic injury, carbuncle is swollen dislikes sore, the cards such as abscess of throat.

Greater celandine: bitter, cool in nature, attach to the lung and stomach meridians, have relieving spasm and pain, relieving cough and asthma effect, cures mainly analgesia, cough-relieving, and diuresis is detoxified.Control gastrointestinal distress, jaundice, oedema, mange sore swells, the cards such as snake bite and insect sting.

Cacumen biotae: latin name platycladicacumen, bitter, puckery, cold in nature, enter the heart, liver, large intestine channel, there is cooling blood and hemostasis, wines used as antirheumatic, effect of loose pyogenic infections, cures mainly haematemesis, bleeding from five sense organs or subcutaneous tissue, hematuria, bloody flux, intestines wind, uterine bleeding, arthralgia due to wind-dampness, bacillary dysentery, hypertension, cough, erysipelas, mumps, the cards such as scald.

Yncaria stem with hooks: taste is sweet, slightly warm in nature, enters Liver Channel, has the effect of heat-clearing, calming the liver, relieving convulsion and spasm, and be mainly used in the anxious raw wind of heat or the caused spasm of liver wind agitation, twitch, restlessness, liver-yang hyperactivity or Liver Channel have the headache of heat dizzy, the symptoms such as red eye, swell pain.

Cayropteris incana: taste is pungent, warm in nature, have dispelling cold of inducing sweat, the effect of the loose stasis of blood that dehumidifies, cures mainly anemofrigid cold headache, cough, pertussis, coldness and pain in the epigastrium, dyspeptic vomiting and diarrhea, cold stasis of blood dysmenorrhoea, the stagnant stomachache of the stasis of blood in postpartum, and wind-cold-dampness arthralgia falls dozen stasis of blood and swells, eczema, the cards such as snakebite.

Chinese tamarisk: be the browse of suspend platymiscium Chinese tamarisk, taste is sweet, pungent, property is put down, and return lung, stomach, the heart channel of Hang-Shaoyin, have dispelling wind, induce sweat, promoting eruption, effect of removing toxic substances, cures mainly anemopyretic cold, and measles goes out saturating from the beginning of, rash, arthralgia due to wind-dampness, the cards such as pruitus.

Cattail pollen: taste is sweet, property is put down, and enters liver, pericardium channel, has hemostasis, stagnation resolvation, treating stranguria effect.For spitting blood, bleeding from five sense organs or subcutaneous tissue, spitting of blood, uterine bleeding, traumatism and bleeding, through closing dysmenorrhoea, gastral cavity ventral spine pain, tumbling and swelling, the cards such as blood strangury and dry pain.

Corydalis tuber: bitter, pungent, warm in nature, returns liver, the heart, stomach warp, has benefaction and wander away, can rise and can fall, have promoting blood circulation to remove blood stasis, effect of promoting qi circulation and relieving pain, cures mainly chest impediment and cardialgia, the side of body rib, all pains of gastral cavity abdomen, headache, pain in the back, hernia pain, muscle and bone ache, dysmenorrhoea, through closing, postpartum the stasis of blood suffer from abdominal pain, the cards such as traumatic injury.

Madder: cold in nature, bitter, returns Liver Channel, effect: cooling blood and hemostasis; Promoting blood circulation and removing blood stasis, cure mainly: blood-head spitting of blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, hematuria, have blood in stool, uterine bleeding, through closing, postpartum stasis blocking stomachache, the card such as traumatic injury, arthralgia due to wind-dampness, jaundice, sore carbuncle, hemorrhoid are swollen.

Fritillaria thunbergii: bitter, cold in nature, enter lung, the heart channel of Hang-Shaoyin, have clearing heat and eliminating phlegm, effect of powder detoxifcation, cures mainly cough due to wind-heat evil, lung carbuncle larynx numbness, scrofula, the cards such as sore swollen toxin.

The wind-weed: be autonomic drug, bitter, sweet, cold in nature, enter lung, stomach, kidney channel, have rush down clearly stomach fire, relieving restlessness of purging heat, the effect of nourshing Yin and drynsessmoistening prescription, removing heat from the lung to relieve cough, cure mainly fever caused by exogenous pathogenic factors, high heat is irritated, lung-heat type cough, and interior heat such as to be quenched one's thirst at the symptom; Its bitter cold matter is moistened, and property sedimentation can heat-clearing, can promote the production of body fluid again, kindly controls warm disease and evil and enters gas and divide, and heat is contained and hindered Tianjin; Also diabetes is used for the treatment of; Phlegm-heat obstructing lung and breathing heavily, xeropulmonary cough, phlegm is few unfavorable; Fire excess from yin deficiency, the diseases such as flaring up of deficient fire.

Reticulate millettia: latin name spatholobicaulis, bitter, sweet, warm in nature, enter liver, kidney channel, there is hemangiectasis, enrich blood and invigorate blood circulation, menstruation regulating, the effect of stimulating the circulation of the blood and cause the muscles and joints to relax, there is obvious inhibitory action to platelet aggregation, promote animal kidney and the total phosphorus metabolism in uterus, be mainly used in treating the irregular menstruation that the deficiency of blood has silt, limbs pain is meciless, the card such as soreness and weakness of waist and knees, pain.

Oyster: taste becomes, and cold nature, returns liver, courage, kidney channel, has calming the liver, tranquillizing the mind by relieving convulsion, softening and resolving hard mass, restrains astringent or styptic treatment for spontaneous sweating effect, cure mainly dizzy tinnitus, brothers' chatter, palpitation and insomnia, have the fidgets, frightened epilepsy is demented, scrofula goiter and tumor, breast lumps, spontaneous sweating, seminal emission frequent micturition, under uterine bleeding band, acid regurgitation is had a stomachache, the cards such as eczema sore.

Veined inula root: for composite family Inulaplants shows the root of arteries and veins Inula britannica chinensis, taste is pungent, bitter, warm in nature, has wines used as antirheumatic, and stimulate the menstrual flow network, the effect of the long-pending pain relieving that disappears, cures mainly rheumatalgia pain, coldness and pain in the epigastrium, dyspeptic abdominal distention, the cards such as rheumatism beriberi.

In described step-down health preserving tea, the weight of each raw material is respectively the corresponding ginseng 4g ~ 6g of every 200g Laoshan green tea, parasitic loranthus 1g ~ 3g, cogongrass rhizome 2g ~ 4g, selfheal 2g ~ 4g, root of bidentate achyranthes 3g ~ 5g, greater celandine 1g ~ 3g, cacumen biotae 2g ~ 4g, yncaria stem with hooks 2g ~ 4g, cayropteris incana 1g ~ 3g, strange willow 2g ~ 4g, cattail pollen 2g ~ 4g, corydalis tuber 1g ~ 3g, madder 2g ~ 4g, fritillaria thunbergii 1g ~ 3g, wind-weed 2g ~ 4g, reticulate millettia 3g ~ 5g, oyster 2g ~ 4g and veined inula root 1g ~ 3g.

Further preferably, in described step-down health preserving tea, the weight of each raw material is respectively the corresponding ginseng 5g of every 200g Laoshan green tea, parasitic loranthus 2g, cogongrass rhizome 3g, selfheal 3g, root of bidentate achyranthes 4g, greater celandine 2g, cacumen biotae 3g, yncaria stem with hooks 3g, cayropteris incana 2g, strange willow 3g, cattail pollen 3g, corydalis tuber 2g, madder 3g, fritillaria thunbergii 2g, wind-weed 3g, reticulate millettia 4g, oyster 3g and veined inula root 2g.

The first step, the process of Laoshan green tea;

Second step, the preparation of Chinese medicine concoction;

In the described first step, the process of Laoshan green tea is specially tealeaves to be placed in food steamer further and evenly spreads out, and food steamer is put into boiler boiling 20min ~ 30min, boiling is complete, tealeaves is tedded under sunlight, allow sunlight carry out nature dehumidifier to tealeaves, described tealeaves dehumidifier reaches 60% ~ 80%, the tealeaves after dehumidifier is put into kneading machine and kneads, the time of kneading is 10min ~ 15min, obtains the tealeaves after process.

Described second step is specially each Chinese medicine material composition further and shreds respectively, and the product of chopping mixes according to above-mentioned weight portion, obtains mixture, add the water relative to this mixture 3 ~ 5 times of quality, soak 1 hour, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, and filter residue adds the water relative to mixture 2 ~ 4 times of quality again, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, the filtered fluid mixing of twice, reduced pressure concentration, obtaining crude drug concentration is the concoction of 0.3g/ml.

Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.

Embodiment 1 Chinese medicine concoction 1

Get ginseng 5g, parasitic loranthus 2g, cogongrass rhizome 3g, selfheal 3g, root of bidentate achyranthes 4g, greater celandine 2g, cacumen biotae 3g, yncaria stem with hooks 3g, cayropteris incana 2g, strange willow 3g, cattail pollen 3g, corydalis tuber 2g, madder 3g, fritillaria thunbergii 2g, wind-weed 3g, reticulate millettia 4g, oyster 3g and veined inula root 2g, shred respectively, the product of chopping mixes, obtain mixture, add the water of 200g, soak 1 hour, be heated to boiling, decoct 3 hours, decoction liquor is filtered, filter residue adds the water of 160g again, be heated to boiling, decoct 3 hours, decoction liquor is filtered, the filtered fluid mixing of twice, reduced pressure concentration, obtaining crude drug concentration is the concoction of 0.3g/ml.

Toxicology test

Acute toxicity test: cleaning grade male and female mouse is divided into administration group and control group at random, administration group feeds the Chinese medicine concoction 1 of raising embodiment 1 and preparing, concentrate and be configured to maximum administration concentration, 2.5g crude drug/ml, 90ml/kg, control group is fed and is raised disinfectant, 90ml/kg, divide equally three administrations feedwater, within every 4 hours, be administered once, normal breeding observing one week.During administration feedwater, each group mouse behavioral activity is normal, has no movable and reduces, rolls up, the phenomenon such as pine tag, and nose, eye, oral cavity have no secretion, none dead mouse.The maximum dosage of mouse is 260g crude drug/kg body weight.The above results shows, when the maximum dosage of mouse is 260g crude drug/kg, concoction of the present invention has no acute toxic reaction.

Long term toxicity test: observe Chinese medicine concoction 1 gavage 180 days body weight on rat, hematological indices, serological biochemical markers and Main Organ Coefficients and histological impact continuously prepared by embodiment 1.Cleaning grade male and female rat is divided into large, medium and small administration group and Normal group at random.Large, medium and small administration group dosage is respectively 80,50,25g crude drug/kg/d.Continuous oral administration 180 days.Experimental result shows, during administration, the behavior of each group rat outward appearance, body weight, food-intake are all normal, has no movable and reduces, rolls up, the phenomenon such as pine tag, and nose, eye, oral cavity have no secretion; When routine blood test [RBC, HGB, HCT, PLT, WBC and classification (LYM, MID, GRA) thereof], blood coagulation, (CT) is all normal.Biochemical indicator: comprise liver function (AST, ALT), renal function (BUN, Crea), alkaline phosphatase (ALP), total serum protein (TP), albumin (ALB) and cholesterol (TC), blood sugar (GLU), 90 days upon administration, 180 days compared with corresponding control group, all within the scope of normal variation, have no significant change.Rat administration histoorgan (heart, liver,kidney,spleen, lung, adrenal gland, thymus gland, testis, epididymis, uterus and ovary, brain, stomach, pancreas, thyroid gland) organ index of two weeks after 90,180 days and after drug withdrawal, visual inspection and Histological section check and are showed no obvious pathological change.The above results shows, concoction composition 80g crude drug/kg, 50g crude drug/kg and 25g crude drug/kg successive administration of the present invention has no overt toxicity reaction for 6 months.

Embodiment 2 Chinese medicine concoction 2

Get ginseng 4g, parasitic loranthus 1g, cogongrass rhizome 2g, selfheal 2g, root of bidentate achyranthes 3g, greater celandine 1g, cacumen biotae 2g, yncaria stem with hooks 2g, cayropteris incana 1g, strange willow 2g, cattail pollen 2g, corydalis tuber 1g, madder 2g, fritillaria thunbergii 1g, wind-weed 2g, reticulate millettia 3g, oyster 2g and veined inula root 1g, shred respectively, the product of chopping mixes, obtain mixture, add the water of 150g, soak 1 hour, be heated to boiling, decoct 3 hours, decoction liquor is filtered, filter residue adds the water of 100g again, be heated to boiling, decoct 3 hours, decoction liquor is filtered, the filtered fluid mixing of twice, reduced pressure concentration, obtaining crude drug concentration is the concoction of 0.3g/ml.

Embodiment 3 Chinese medicine concoction 3

Get ginseng 6g, parasitic loranthus 3g, cogongrass rhizome 4g, selfheal 4g, root of bidentate achyranthes 5g, greater celandine 3g, cacumen biotae 4g, yncaria stem with hooks 4g, cayropteris incana 3g, strange willow 4g, cattail pollen 4g, corydalis tuber 3g, madder 4g, fritillaria thunbergii 3g, wind-weed 4g, reticulate millettia 5g, oyster 4g and veined inula root 3g, shred respectively, the product of chopping mixes, obtain mixture, add the water of 250g, soak 1 hour, be heated to boiling, decoct 3 hours, decoction liquor is filtered, filter residue adds the water of 200g again, be heated to boiling, decoct 3 hours, decoction liquor is filtered, the filtered fluid mixing of twice, reduced pressure concentration, obtaining crude drug concentration is the concoction of 0.3g/ml.

The process of embodiment 4 Laoshan green tea

Tealeaves is placed in food steamer and evenly spreads out, and food steamer is put into boiler boiling 30min, boiling is complete, tealeaves is tedded under sunlight, allow sunlight carry out nature dehumidifier to tealeaves, described tealeaves dehumidifier reaches 80%, the tealeaves after dehumidifier is put into kneading machine and kneads, the time of kneading is 15min, obtains the tealeaves after process.

Embodiment 5 step-down health preserving tea

Laoshan green tea after embodiment 4 being processed joins in the middle of Chinese medicine concoction 1 prepared by embodiment 1, stirs, and adopt the warm water of 60 DEG C to boil 40min subsequently, the tealeaves after boiling is pulled out, puts into dryer and carries out oven dry and obtain step-down health preserving tea.

Embodiment 6 animal experiment

Animal used as test

SD rat 40, male and female are not limit, every only about (250 ± 20) g, clean animal, quarantines qualified, is provided by Qingdao City animal used as test and animal experimental center, spontaneous hypertensive rat in 14 week age (SHR) 30, male and female half and half, body weight (225 ± 30) g, is provided by Qingdao City animal used as test and animal experimental center.Male and female divide cage, and standard feed and running water are fed, and raise in the quiet receptacle of constant temperature (22 ± 2) DEG C, constant humidity (55 ± 5) %, each 12h of artificial lighting light and shade.

Test products

Step-down health preserving tea prepared by embodiment 5

Test method

Rat test

Normal rat is divided into 2 groups at random, test group 15, gavages 10 times amount, the Normal group 10 of human body routine use amount by body weight ratio, gavage physiological saline.Spontaneous hypertensive rat (SHR) gavages 10 times amount of human body routine use amount by body weight ratio.Every day at the upper and lower noon respectively organizes half amount medicine once, successive administration 20d, experimental session drinking water for animals and ingest arbitrarily.Front electrothermostat rat being put into 37 DEG C of pressure measurement is heated and mouse arteria caudalis is fully expanded, after 15 seconds, by Conscious Rat blood pressure heart rate analyzer (HX mono-type, Beijing China-Japan Friendship Hospital produces) measure rat tail artery systolic pressure and heart rate, experiment start and at the end of respectively carry out once, survey continuously and average as measured value for 3 times.

Data statistics

Experimental data mean+SD represent, adopt SPSS15.0 software to carry out the analysis of single factor test variance statistic to data, group difference adopts Duncan Multiple range test, and the level of signifiance is P < 0.05.

Result

Normal rat blood pressure and Heart rate influences, the results are shown in Table 1.

The impact of table 1 normal rat blood pressure and heart rate

Table 1 result is seen, the blood pressure of test group animal compared with normal control animals obviously declines (P < 0.01), changes in heart rate there was no significant difference (P > 0.05), illustrate that the blood pressure of step-down health preserving tea to intact animal has reducing effect, but on the heart rate of rat without impact.

On the impact of hypertensive rat blood pressure and heart rate, the results are shown in Table 2.

Table 2 hypertensive rat blood pressure and changes in heart rate

Table 2 is known, adopts step-down health preserving tea provided by the invention obviously can reduce rat blood pressure and the heart rate of High Pressure Model group.

Embodiment 7 clinical data

Patient data

Selected patient meets

Diagnosing Hypertension standard 1,2 grades, TCM Syndrome Type belongs to dizzy type of deficiency of YIN leading to hyper activity of YANG.Select 200 routine hyperpietics, be divided into step-down health preserving tea group and western medicine group, western medicine group gives Amlodipine Besylate Tablet (the Suzhou auspicious pharmacy in east, 5mg/ sheet) 5mg, every day 1 time, the step-down health preserving tea boiling water that treatment group coordinates embodiment 5 to prepare on the basis that western medicine group is treated brews offspring's tea-drinking, every day 2 times, each 3 _gtreatment.The indexs such as two groups of ages, sex, the course of disease and blood pressure level are through statistical procedures, and difference there are no significant meaning (P > 0.05), have comparativity, two groups of courses for the treatment of are 2 months.

Diagnostic criteria

Western medicine diagnose standard: with reference to the diagnostic criteria in " Chinese hypertension prevention and control guide in 2010 ".

TCM syndrome diagnostic criteria: with reference to the syndrome of hyperactivity of yang due to yin deficiency standard formulation that " new Chinese medicine guideline of clinical investigations " is dizzy.Primary symptom: dizzy, headache, the soreness of waist, knee are soft, dysphoria in chestpalms-soles.Secondary disease: palpitaition, insomnia, tinnitus, forgetful, constipation, bitter taste, the red few tongue of tongue, small and wiry pulse and counting.Above primary symptom 2 adds 1 time disease, or primary symptom 1 adds 2 diseases and diagnosable.

Excluded cases: 1,3 grades of hypertension; 2, secondary hypertension; 3, the age is under-18s, gestation or women breast-feeding their children; 4, merge intentionally, brain, liver, the serious primary disease such as kidney and hemopoietic system, mental patient; 5, allergic constitution or to multi-medicament allergy sufferers.

Observation of curative effect

Criterion of therapeutical effect: with reference to the efficacy assessment standard of " new Chinese medicine guideline of clinical investigations ", express by clinical effective, effective, invalid 3 levels, and according to treating forward and backward cardinal symptom integral and calculating therapeutic index, judge total effects.

Blood pressure curative effect determinate standard: (1) is effective: 1, diastolic pressure more than decline 10mmHg, and reach normal range (NR); Though 2, diastolic pressure is not down to normally but decline 20mmHg or more.(2) effective: 1, diastolic pressure declines not as good as 10mmHg, but reaches normal range (NR); 2, diastolic pressure comparatively treats the front 10 ~ 19mmHg that declines, and does not reach normal range (NR); 3, systolic pressure comparatively treats front more than decline 30mmHg.Wherein 1 must be possessed.(3) invalid: not reach above standard person.

Tcm syndrome curative effect determinate standard: 1, effective: clinical symptoms, sign are obviously improved, syndrome integral reduces >=70%.2, effective: clinical symptoms, sign all take a favorable turn, syndrome integral reduces >=30%.3, invalid: clinical symptoms, sign are not improved, even increase the weight of, syndrome integral reduces less than 30%.

Safety indexes is observed: all have a blood test after treatment before 200 routine patient therapy routine urinalysis, hepatic and renal function, blood fat, electrolyte.

Data statistics

Result

Efficacy of antihypertensive treatment compares, and the results are shown in Table 3.

Table 3 efficacy of antihypertensive treatment compares

Group	n	Effective	Effectively	Invalid	Total effective rate
						Health preserving tea group	100	92	6	2	98.0％
Control group	100	86	7	7	93.0％

Two groups are passed through treatment, and result shows: step-down health preserving tea group comparatively western medicine group curative effect has clear improvement (P < 0.05).

Before and after treatment, tcm syndrome comparitive study, the results are shown in Table 4.

Front and back tcm syndrome comparitive study treated by table 4

Group	n	Effective	Effectively	Invalid	Total effective rate
						Health preserving tea group	100	90	6	4	96.0％
Control group	100	75	10	15	85.0％

Two groups through treatment, result show: health preserving tea group comparatively control group tcm syndrome curative effect there were significant differences (P < 0.05).

Safety indexes is observed

Two groups of patient's blood urine routines, hepatic and renal function, blood fat, electrolyte inspections have no significant change before comparatively treating.

All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.

The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims

1. a step-down health preserving tea, is characterized in that: raw material comprises Laoshan green tea, ginseng, parasitic loranthus, cogongrass rhizome, selfheal, the root of bidentate achyranthes, greater celandine, cacumen biotae, yncaria stem with hooks, cayropteris incana, strange willow, cattail pollen, corydalis tuber, madder, fritillaria thunbergii, the wind-weed, reticulate millettia, oyster and veined inula root.

2. step-down health preserving tea as claimed in claim 1, is characterized in that: the weight of each raw material is respectively the corresponding ginseng 4g ~ 6g of every 200g Laoshan green tea, parasitic loranthus 1g ~ 3g, cogongrass rhizome 2g ~ 4g, selfheal 2g ~ 4g, root of bidentate achyranthes 3g ~ 5g, greater celandine 1g ~ 3g, cacumen biotae 2g ~ 4g, yncaria stem with hooks 2g ~ 4g, cayropteris incana 1g ~ 3g, strange willow 2g ~ 4g, cattail pollen 2g ~ 4g, corydalis tuber 1g ~ 3g, madder 2g ~ 4g, fritillaria thunbergii 1g ~ 3g, wind-weed 2g ~ 4g, reticulate millettia 3g ~ 5g, oyster 2g ~ 4g and veined inula root 1g ~ 3g.

3. step-down health preserving tea as claimed in claim 1 or 2, is characterized in that: the weight of each raw material is respectively the corresponding ginseng 5g of every 200g Laoshan green tea, parasitic loranthus 2g, cogongrass rhizome 3g, selfheal 3g, root of bidentate achyranthes 4g, greater celandine 2g, cacumen biotae 3g, yncaria stem with hooks 3g, cayropteris incana 2g, strange willow 3g, cattail pollen 3g, corydalis tuber 2g, madder 3g, fritillaria thunbergii 2g, wind-weed 3g, reticulate millettia 4g, oyster 3g and veined inula root 2g.

4. the preparation method of step-down health preserving tea described in claims 1 to 3, is characterized in that, comprising:

The first step, the process of Laoshan green tea;

Second step, the preparation of Chinese medicine concoction;

5. the preparation method of step-down health preserving tea as claimed in claim 4, it is characterized in that: in the described first step, the process of Laoshan green tea is specially tealeaves to be placed in food steamer further and evenly spreads out, and food steamer is put into boiler boiling 20min ~ 30min, boiling is complete, tealeaves is tedded under sunlight, sunlight is allowed to carry out nature dehumidifier to tealeaves, described tealeaves dehumidifier reaches 60% ~ 80%, tealeaves after dehumidifier is put into kneading machine knead, the time of kneading is 10min ~ 15min, obtains the tealeaves after process.

6. the preparation method of the step-down health preserving tea as described in claim 4 or 5, it is characterized in that: described second step is specially each Chinese medicine material composition further and shreds respectively, the product of chopping mixes according to above-mentioned weight portion, obtain mixture, add the water relative to this mixture 3 ~ 5 times of quality, soak 1 hour, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, filter residue adds the water relative to mixture 2 ~ 4 times of quality again, be heated to boiling, decoct 2 ~ 3 hours, decoction liquor is filtered, the filtered fluid mixing of twice, reduced pressure concentration, obtaining crude drug concentration is the concoction of 0.3g/ml.