CN105012479A - Acne treatment composition and application thereof and acne treatment cream containing acne treatment composition - Google Patents
Acne treatment composition and application thereof and acne treatment cream containing acne treatment composition Download PDFInfo
- Publication number
- CN105012479A CN105012479A CN201510433429.4A CN201510433429A CN105012479A CN 105012479 A CN105012479 A CN 105012479A CN 201510433429 A CN201510433429 A CN 201510433429A CN 105012479 A CN105012479 A CN 105012479A
- Authority
- CN
- China
- Prior art keywords
- extract
- acne
- parts
- removing composition
- acne treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010000496 acne Diseases 0.000 title claims abstract description 79
- 208000002874 Acne Vulgaris Diseases 0.000 title claims abstract description 73
- 239000000203 mixture Substances 0.000 title claims abstract description 61
- 239000006071 cream Substances 0.000 title abstract description 5
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 33
- 241001135917 Vitellaria paradoxa Species 0.000 claims abstract description 18
- 235000018936 Vitellaria paradoxa Nutrition 0.000 claims abstract description 18
- -1 polydimethylsiloxane Polymers 0.000 claims abstract description 15
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims abstract description 12
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims abstract description 11
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 11
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 claims abstract description 11
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims abstract description 11
- LXAHHHIGZXPRKQ-UHFFFAOYSA-N 5-fluoro-2-methylpyridine Chemical compound CC1=CC=C(F)C=N1 LXAHHHIGZXPRKQ-UHFFFAOYSA-N 0.000 claims abstract description 11
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 11
- OQILCOQZDHPEAZ-UHFFFAOYSA-N Palmitinsaeure-octylester Natural products CCCCCCCCCCCCCCCC(=O)OCCCCCCCC OQILCOQZDHPEAZ-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229920001214 Polysorbate 60 Polymers 0.000 claims abstract description 11
- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 claims abstract description 11
- 229940081733 cetearyl alcohol Drugs 0.000 claims abstract description 11
- 239000004205 dimethyl polysiloxane Substances 0.000 claims abstract description 11
- GJQLBGWSDGMZKM-UHFFFAOYSA-N ethylhexyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(CC)CCCCC GJQLBGWSDGMZKM-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229940075529 glyceryl stearate Drugs 0.000 claims abstract description 11
- 229960003639 laurocapram Drugs 0.000 claims abstract description 11
- 229940041616 menthol Drugs 0.000 claims abstract description 11
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims abstract description 11
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229940100460 peg-100 stearate Drugs 0.000 claims abstract description 11
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims abstract description 11
- 229920002401 polyacrylamide Polymers 0.000 claims abstract description 11
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 claims abstract description 11
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 claims abstract description 11
- 229940113124 polysorbate 60 Drugs 0.000 claims abstract description 11
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229960003415 propylparaben Drugs 0.000 claims abstract description 11
- 229950011392 sorbitan stearate Drugs 0.000 claims abstract description 11
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
- 230000003255 anti-acne Effects 0.000 claims description 17
- 235000013399 edible fruits Nutrition 0.000 claims description 16
- 210000000582 semen Anatomy 0.000 claims description 14
- 241000124033 Salix Species 0.000 claims description 13
- 239000000463 material Substances 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 12
- HPEUJPJOZXNMSJ-UHFFFAOYSA-N Methyl stearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC HPEUJPJOZXNMSJ-UHFFFAOYSA-N 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 9
- 239000002994 raw material Substances 0.000 claims description 5
- 238000006243 chemical reaction Methods 0.000 claims description 4
- 239000008346 aqueous phase Substances 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 239000012071 phase Substances 0.000 claims description 3
- 244000146462 Centella asiatica Species 0.000 abstract description 2
- 235000004032 Centella asiatica Nutrition 0.000 abstract description 2
- 244000124853 Perilla frutescens Species 0.000 abstract description 2
- 241000972673 Phellodendron amurense Species 0.000 abstract description 2
- 240000004922 Vigna radiata Species 0.000 abstract description 2
- 235000010721 Vigna radiata var radiata Nutrition 0.000 abstract description 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 241001328813 Methles Species 0.000 abstract 1
- 235000004347 Perilla Nutrition 0.000 abstract 1
- 235000011469 Vigna radiata var sublobata Nutrition 0.000 abstract 1
- 229940069765 bean extract Drugs 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 235000020215 hypoallergenic milk formula Nutrition 0.000 abstract 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 abstract 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 abstract 1
- 229960002216 methylparaben Drugs 0.000 abstract 1
- 231100000344 non-irritating Toxicity 0.000 abstract 1
- 229940050101 salix nigra bark extract Drugs 0.000 abstract 1
- 229940057910 shea butter Drugs 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 40
- 238000012360 testing method Methods 0.000 description 16
- 239000003925 fat Substances 0.000 description 15
- 230000000694 effects Effects 0.000 description 12
- 241000700647 Variola virus Species 0.000 description 9
- 206010061218 Inflammation Diseases 0.000 description 5
- 230000004054 inflammatory process Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 239000011148 porous material Substances 0.000 description 5
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 5
- 241000196324 Embryophyta Species 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 230000008929 regeneration Effects 0.000 description 4
- 238000011069 regeneration method Methods 0.000 description 4
- 230000008439 repair process Effects 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 210000003780 hair follicle Anatomy 0.000 description 3
- 210000002268 wool Anatomy 0.000 description 3
- 206010048768 Dermatosis Diseases 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 241001278079 Salix nigra Species 0.000 description 2
- 230000007815 allergy Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 239000007933 dermal patch Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 239000004519 grease Substances 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 238000002647 laser therapy Methods 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 235000014593 oils and fats Nutrition 0.000 description 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 229960004889 salicylic acid Drugs 0.000 description 2
- 210000001732 sebaceous gland Anatomy 0.000 description 2
- 208000017520 skin disease Diseases 0.000 description 2
- 239000002689 soil Substances 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- TUSDEZXZIZRFGC-UHFFFAOYSA-N 1-O-galloyl-3,6-(R)-HHDP-beta-D-glucose Natural products OC1C(O2)COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC1C(O)C2OC(=O)C1=CC(O)=C(O)C(O)=C1 TUSDEZXZIZRFGC-UHFFFAOYSA-N 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 241001116389 Aloe Species 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 241000288570 Chionochloa conspicua Species 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 239000001263 FEMA 3042 Substances 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- 240000002045 Guettarda speciosa Species 0.000 description 1
- 235000001287 Guettarda speciosa Nutrition 0.000 description 1
- 235000003935 Hippophae Nutrition 0.000 description 1
- 241000229143 Hippophae Species 0.000 description 1
- LRBQNJMCXXYXIU-PPKXGCFTSA-N Penta-digallate-beta-D-glucose Natural products OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-PPKXGCFTSA-N 0.000 description 1
- 235000004348 Perilla frutescens Nutrition 0.000 description 1
- 206010062519 Poor quality sleep Diseases 0.000 description 1
- 244000234609 Portulaca oleracea Species 0.000 description 1
- 235000001855 Portulaca oleracea Nutrition 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000899950 Salix glauca Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 235000006468 Thea sinensis Nutrition 0.000 description 1
- 230000009102 absorption Effects 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 235000011399 aloe vera Nutrition 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000010065 bacterial adhesion Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 150000001277 beta hydroxy acids Chemical class 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 238000010612 desalination reaction Methods 0.000 description 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 description 1
- 229960003957 dexamethasone Drugs 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 210000000750 endocrine system Anatomy 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 230000003779 hair growth Effects 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000000774 hypoallergenic effect Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- DUWWHGPELOTTOE-UHFFFAOYSA-N n-(5-chloro-2,4-dimethoxyphenyl)-3-oxobutanamide Chemical compound COC1=CC(OC)=C(NC(=O)CC(C)=O)C=C1Cl DUWWHGPELOTTOE-UHFFFAOYSA-N 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 230000036560 skin regeneration Effects 0.000 description 1
- 210000003859 smegma Anatomy 0.000 description 1
- 238000013112 stability test Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 229920002258 tannic acid Polymers 0.000 description 1
- LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 description 1
- 229940033123 tannic acid Drugs 0.000 description 1
- 235000015523 tannic acid Nutrition 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses an acne treatment composition and application thereof and an acne treatment cream containing the acne treatment composition. The acne treatment composition comprises shea butter, Chinese corktree bark extract, salix nigra bark extract, herba portulacae extract, purple perilla extract, asiatic pennywort herb extract and mung bean extract, effectively conditions acne skins and inhibits reproduction of acne, smoothens acne and removes acne marks, and can be applied to skin directly or added into acne treatment products. The acne treatment cream comprises the acne treatment composition, cetearyl alcohol, ethylhexyl palmitate, polydimethylsiloxane, glyceryl stearate, PEG-100 stearate, caprylic/capric triglyceride, propylene glycol, polyacrylamide, polysorbate-60, sorbitan stearate, laurocapram, PEG-20 methl glucse sesquistearate, menthol, borneol, edta disodium, methylparaben, propyl hydroxybenzoate and water. The acne treatment cream prepared by a hypo-allergenic formula is mild and non-irritating, easy to absorb, non-greasy, safe and effective.
Description
Technical field
The invention belongs to cosmetic technical field, be specifically related to a kind of acne-removing composition and application and the Whelk-eliminating paste containing this acne-removing composition in anti-acne skin care item.
Background technology
Pox is being commonly called as of acne, cries again " pimples " " acne " " whelk " " skin sore " etc., is that a kind of chronic inflammatory skin that inflammation causes is sick because hair follicle and sebaceous gland are blocked.During adolescence, the hormone meeting stimulating hair growth in body, promote smegma more heavy wool fat, therefore hair and sebaceous gland pile up many materials, make oils and fats and bacterial adhesion, cause the reaction of red swelling of the skin.Because this symptom is common in youth of both sexes, so just claim it to be " comedo ".In fact, teenager not necessarily all can long comedo, and comedo also not necessarily only appears at it teenager.Because present environmental pollution is serious, the dust in air etc. directly contact with face skin, are easy to be adsorbed on skin block pore, and computer radiate source has influence on the disorder of human endocrine system, thus makes skin metabolism irregular; Diet is irregular, poor sleep, pressure etc. all can cause growing of pox.
The method of existing anti-acne has a variety of, 1, as laser therapy comedo method, its energy rapid damage propanoic acid comedo bacillus, effective anti-bacteria breeding, eliminate it to the stimulation of tissue and destruction, but the effect of laser therapy is too strong, and just physical method destroys funny, can not fundamentally anti-acne; 2, some natural plant component, Chinese medicinal ingredients or the Chinese medicines such as Aloe, Flos Matricariae chamomillae, Camellia sinensis, Fructus Hippophae are utilized to mix composition anti-acne with plant, existing this anti-acne method safety, regulation of skin oils and fats can be played thus the effect of fundamentally anti-acne, but marking when using this natral plant ingredients anti-acne after time length, anti-acne is not easily removed completely, and formula needs to be improved; 3, utilize some Western medicine such as salicylic acid, Bo Nisong, dexamethasone except pox, the side effect of Western medicine is strong, and cost is high.Therefore, be necessary that a kind of effectively conditioning of research and development pox flesh suppresses small pox regeneration, smooth pox hole, and gentleness do not stimulate, the Whelk-eliminating paste of hypoallergenic safety.
Chinese patent application CN 103622885A discloses a kind of acne-removing composition containing Butyrospermum parkii fruit fat, Angelica roots, Rhizoma Atractylodis Macrocephalae root extract, Herba Centellae extract.Chinese patent application CN 104586667A discloses a kind of acne eliminating cream containing Cortex Phellodendri extract, Radix Sophorae Flavescentis extract, Herba Lophatheri extract etc.Chinese patent application CN 104188849A discloses a kind of anti-acne control fluid composition containing Herba portulacae extract, white willow peel extract.Through retrieval, not yet find that there is compositions and the application of said composition in anti-acne skin care item of Butyrospermum parkii fruit fat, Cortex Phellodendri extract, black extract of willow bark, Herba portulacae extract, Folium perillae extract, Herba Centellae extract and Semen phaseoli radiati extract at present.
Summary of the invention
The object of the present invention is to provide a kind of acne-removing composition, this acne-removing composition can effectively be nursed one's health pox flesh and suppress small pox to regenerate, and smooths pox hole, desalination pox print.
The present invention is by the following technical programs to realize above-mentioned purpose: a kind of acne-removing composition, comprises following component: Butyrospermum parkii fruit fat, Cortex Phellodendri extract, black extract of willow bark, Herba portulacae extract, Folium perillae extract, Herba Centellae extract and Semen phaseoli radiati extract.
Further, described acne-removing composition is made up of the component of following weight portion: Butyrospermum parkii fruit 10 ~ 30 parts, fat, Cortex Phellodendri extract 2 ~ 8 parts, black extract of willow bark 2 ~ 8 parts, Herba portulacae extract 2 ~ 10 parts, Folium perillae extract 2 ~ 8 parts, Herba Centellae extract 2 ~ 8 parts and Semen phaseoli radiati extract 3 ~ 10 parts.
As the preferred embodiment of the present invention, described acne-removing composition is made up of the component of following weight portion: Butyrospermum parkii fruit 20 parts, fat, Cortex Phellodendri extract 5 parts, black extract of willow bark 6 parts, Herba portulacae extract 8 parts, Folium perillae extract 5 parts, Herba Centellae extract 5 parts and Semen phaseoli radiati extract 8 parts.
The function and structure of described Butyrospermum parkii fruit fat is very similar to the lipid of skin, therefore be considered to a kind of natural Moisture factor, it can help epidermis cell structure to keep complete, effectively to antibacterium, be conducive to skin healing, prevent skin irritation and make skin regeneration.
Described Cortex Phellodendri extract has the effect of releiving with calm skin, can help rapidly releive skin redness and inflammation situation, and horny layer softening, deep layer reparation, composes flesh floor cells of living.
Described black extract of willow bark is set from the black wool of North American continent east, and fresh black wool tree is containing abundant tannic acid and salicylic acid, and natural salicylic acid to infiltrate through in pore as beta-hydroxy acid thus enter skin depths, does not stimulate while antibacterial.
Described Herba portulacae extract has the effects such as antioxidation, antiinflammatory, moisturizing, and the sense of discomfort of skin of softly releiving, takees good care of tender and lovely skin quality.
Described Folium perillae extract can infiltrate skin very well, alleviates small pox inflammation, reduces the generation of pox print.
Described Herba Centellae extract can promote that in skin corium, collagen protein is formed, and makes fibrin regenerate, makes skin compact smooth, also can help impaired organization healing.
Aminoacid, alkaloid etc. that described Semen phaseoli radiati extract is contained abundant, have the effect of skin of releiving, repair, can remove the dirt of skin pore depths, improves and prevention skin is fuel-displaced, dark and gloomy and small pox problem.
Described Butyrospermum parkii fruit fat and black extract of willow bark effectively antibacterial, but not chafe; Described Cortex Phellodendri extract and Herba portulacae extract are effectively releived the sense of discomfort such as red swelling of the skin, inflammation; Described Folium perillae extract, snow grass extract and Semen phaseoli radiati extract effectively dissolve pore depths grease soils, dredge blockage hair follicle, discharge toxin, reduce pox print, improve skin quality; The each component of acne-removing composition of the present invention is worked in coordination with, and reaches effectively conditioning pox flesh, suppresses small pox regeneration, improve pockmark pox print and skin coarse, progressively deeply desalinate pox print, promote that skin horny layer upgrades, the object of reparation skin.Therefore, directly can be coated with or add in anti-acne skin care item after acne-removing composition mix homogeneously of the present invention and use.
Another object of the present invention is to provide a kind of Whelk-eliminating paste containing acne-removing composition of the present invention and preparation method thereof, and its technical scheme is as follows:
A kind of Whelk-eliminating paste, comprise the raw material of following weight percent meter: described acne-removing composition 2 ~ 8%, cetearyl alcohol 3 ~ 5%, ethylhexyl palmitate 2 ~ 4%, polydimethylsiloxane 2 ~ 4%, glyceryl stearate 0.5 ~ 2%, PEG-100 stearate 0.5 ~ 2%, caprylic/capric triglyceride 1 ~ 3%, propylene glycol 1 ~ 3%, polyacrylamide 0.5 ~ 1.5%, polysorbate-60 1 ~ 1.5%, sorbitan stearate 0.5 ~ 1.5%, laurocapram 0.2 ~ 0.8%, PEG-20 methyl sesquistearate 0.2 ~ 0.8%, menthol 0.2 ~ 0.8%, Borneolum Syntheticum 0.1 ~ 0.3%, EDTA disodium 0.05 ~ 0.15%, methyl hydroxybenzoate 0.05 ~ 0.3%, propyl hydroxybenzoate 0.05 ~ 0.15% and water 70 ~ 80%.
As the preferred embodiment of the present invention, described Whelk-eliminating paste is made up of the raw material of following weight percent meter: described acne-removing composition 6%, cetearyl alcohol 4%, ethylhexyl palmitate 3%, polydimethylsiloxane 3%, glyceryl stearate 1%, PEG-100 stearate 1%, caprylic/capric triglyceride 2%, propylene glycol 2%, polyacrylamide 1%, polysorbate-60 1.2%, sorbitan stearate 1%, laurocapram 0.6%, PEG-20 methyl sesquistearate 0.5%, menthol 0.5%, Borneolum Syntheticum 0.2%, EDTA disodium 0.1%, methyl hydroxybenzoate 0.2%, propyl hydroxybenzoate 0.1% and water 72.6%.
The preparation method of above-mentioned Whelk-eliminating paste comprises the following steps:
S1, cetearyl alcohol, ethylhexyl palmitate, polydimethylsiloxane, glyceryl stearate, PEG-100 stearate, caprylic/capric triglyceride, polysorbate-60, sorbitan stearate, laurocapram, PEG-20 methyl sesquistearate, methyl hydroxybenzoate and propyl hydroxybenzoate are added in oil phase pot, be heated to 75 ~ 85 DEG C while stirring, and be stirred to material and dissolve completely, obtain material one, for subsequent use;
S2, EDTA disodium, water are added in aqueous phase pot, be stirred and heated to 80 ~ 85 DEG C, in suction reaction pot, then by material one suction, open homogenizing, after adding polyacrylamide homogenizing 5 ~ 10min, after insulated and stirred 15min, start cooling simultaneously, add propylene glycol, menthol, Borneolum Syntheticum, acne-removing composition stirring when 45 DEG C, obtain Whelk-eliminating paste.
Further, the mixing speed of described stirring is 40 ~ 50 revs/min.
Therefore, compared with prior art, advantage of the present invention is:
(1) acne-removing composition of the present invention is made up of various plants extract, does not naturally stimulate, effectively antibacterial, to releive the sense of discomfort such as red swelling of the skin, inflammation, more solubilized pore depths grease soils, dredge blockage hair follicle, discharge toxin, supplement skin desired nutritional elite in time, promote skin reparation, compact skin, smooth pox hole, reduce pox print, improve skin quality, suppress small pox regeneration simultaneously.
(2) Whelk-eliminating paste formula gentleness of the present invention does not stimulate, easily absorptions, non-greasy, safe and efficient, can work in coordination with acne-removing composition of the present invention and infiltrate skin fast, the object reaching safe and efficient anti-acne, repair skin, suppress small pox to regenerate; Whelk-eliminating paste raw material of the present invention is easy to get simultaneously, and preparation technology is simple, and condition is easily controlled, and can be applicable.
Detailed description of the invention
Further describe the present invention below by way of detailed description of the invention, but the present invention is not limited only to following examples.Within the scope of the invention or not departing from content of the present invention, spirit and scope, the present invention is suitably improved, replaces the identical component of effect, will become apparent to those skilled in the art that they are all deemed to be included within scope of the present invention.
Butyrospermum parkii fruit fat of the present invention is Butyrospermum parkii (BUTYROSPERMUM PARKII) the fruit fat purchased from Li Meida Fine Chemical Co., Ltd, and article No. is ZJF-01200419;
Described Cortex Phellodendri extract is Cortex Phellodendri (PHELLODENDRON AMURENSE) extract purchased from Guangzhou Ming Hui Fine Chemical Co., Ltd, and article No. is R-646;
Described black extract of willow bark is black willow (SALIX NIGRA) bark extract purchased from Guangzhou Ming Hui Fine Chemical Co., Ltd, and article No. is R-633;
Described Herba portulacae extract is Herba Portulacae (PORTULACA OLERACEA) extract purchased from Eurocostech Co., Ltd, and article No. is 2121115;
Described Folium perillae extract is Folium Perillae (PERILLA OCYMOIDES) extract purchased from Xilong Chemical Co., Ltd, and article No. is 150333;
Described Herba Centellae extract is Herba Centellae (CENTELLA ASIATICA) extract purchased from Shanghai Shun Tuo scientific & trading Co., Ltd., and article No. is ZA015;
Described Semen phaseoli radiati extract is Semen phaseoli radiati (PHASEOLUS RADIATUS) extract purchased from Li Meida Fine Chemical Co., Ltd, and article No. is ZJF-01100400.
embodiment 1, acne-removing composition of the present invention
Butyrospermum parkii fruit 20 parts, fat, Cortex Phellodendri extract 5 parts, black extract of willow bark 6 parts, Herba portulacae extract 8 parts, Folium perillae extract 5 parts, Herba Centellae extract 5 parts and Semen phaseoli radiati extract 8 parts.
embodiment 2, acne-removing composition of the present invention
Butyrospermum parkii fruit 10 parts, fat, Cortex Phellodendri extract 8 parts, black extract of willow bark 8 parts, Herba portulacae extract 10 parts, Folium perillae extract 2 parts, Herba Centellae extract 2 parts and Semen phaseoli radiati extract 3 parts.
embodiment 3, acne-removing composition of the present invention
Butyrospermum parkii fruit 30 parts, fat, Cortex Phellodendri extract 2 parts, black extract of willow bark 2 parts, Herba portulacae extract 2 parts, Folium perillae extract 8 parts, Herba Centellae extract 8 parts and Semen phaseoli radiati extract 10 parts.
comparative example 1,
Butyrospermum parkii fruit 26 parts, fat, Herba portulacae extract 13 parts, Folium perillae extract 9 parts and Herba Centellae extract 9 parts.
embodiment 4, Whelk-eliminating paste of the present invention and preparation thereof
Formula: by weight percentage, the acne-removing composition 6% of embodiment 1, cetearyl alcohol 4%, ethylhexyl palmitate 3%, polydimethylsiloxane 3%, glyceryl stearate 1%, PEG-100 stearate 1%, caprylic/capric triglyceride 2%, propylene glycol 2%, polyacrylamide 1%, polysorbate-60 1.2%, sorbitan stearate 1%, laurocapram 0.6%, PEG-20 methyl sesquistearate 0.5%, menthol 0.5%, Borneolum Syntheticum 0.2%, EDTA disodium 0.1%, methyl hydroxybenzoate 0.2%, propyl hydroxybenzoate 0.1% and water 72.6%.
Preparation: S1, cetearyl alcohol, ethylhexyl palmitate, polydimethylsiloxane, glyceryl stearate, PEG-100 stearate, caprylic/capric triglyceride, polysorbate-60, sorbitan stearate, laurocapram, PEG-20 methyl sesquistearate, methyl hydroxybenzoate and propyl hydroxybenzoate are added in oil phase pot, be heated to 80 DEG C while stirring, and be stirred to material and dissolve completely, obtain material one, for subsequent use;
S2, EDTA disodium, water are added in aqueous phase pot, be stirred and heated to 85 DEG C, in suction reaction pot, then by material one suction, open homogenizing, after adding polyacrylamide homogenizing 5min, after insulated and stirred 15min, start cooling simultaneously, add propylene glycol, menthol, Borneolum Syntheticum, acne-removing composition stirring when 45 DEG C, obtain Whelk-eliminating paste.
The mixing speed of above-mentioned stirring is 45 revs/min.
embodiment 5, Whelk-eliminating paste of the present invention and preparation thereof
Formula: by weight percentage, the acne-removing composition 4% of embodiment 1, cetearyl alcohol 5%, ethylhexyl palmitate 2%, polydimethylsiloxane 4%, glyceryl stearate 0.5%, PEG-100 stearate 2%, caprylic/capric triglyceride 1%, propylene glycol 3%, polyacrylamide 0.5%, polysorbate-60 1.5%, sorbitan stearate 0.5%, laurocapram 0.8%, PEG-20 methyl sesquistearate 0.2%, menthol 0.8%, Borneolum Syntheticum 0.1%, EDTA disodium 0.15%, methyl hydroxybenzoate 0.05%, propyl hydroxybenzoate 0.15% and water 73.75%.
Preparation method is with embodiment 4.
embodiment 6, Whelk-eliminating paste of the present invention and preparation thereof
Formula: by weight percentage, the acne-removing composition 8% of embodiment 1, cetearyl alcohol 3%, ethylhexyl palmitate 4%, polydimethylsiloxane 2%, glyceryl stearate 2%, PEG-100 stearate 0.5%, caprylic/capric triglyceride 3%, propylene glycol 1%, polyacrylamide 1.5%, polysorbate-60 1%, sorbitan stearate 1.5%, laurocapram 0.2%, PEG-20 methyl sesquistearate 0.8%, menthol 0.2%, Borneolum Syntheticum 0.3%, EDTA disodium 0.05%, methyl hydroxybenzoate 0.3%, propyl hydroxybenzoate 0.05% and water 70.6%.
Preparation method is with embodiment 4.
test example one, Product Safety evaluation (experiment of human body skin patch)
One, trial target: the acne-removing composition of embodiment 1 ~ 3, the Whelk-eliminating paste of embodiment 4 ~ 6
Tested crowd's number: 60 people, women
Age: between 20 ~ 50 years old
Health status: subjects skin is healthy, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Grouping: 6 groups, often organize 10 people, 28 ± 2 years old mean age.
Two, patch method: select qualified speckle examination device, with closed patch experiment method, tested material being about 0.020g ~ 0.025g drips in speckle examination device, external special adhesive tape is covered on experimenter back, tested material is removed after 24 hours, within after removing respectively 0.5,6,12,24,48 hour, observe dermoreaction, according to its result of dermoreaction grade scale record in " cosmetics health specification ".
Three, experimental result: human skin patch result shows: each group experimenter is by the patch test of the acne-removing composition of embodiment 1 ~ 3, the Whelk-eliminating paste of embodiment 4 ~ 6, dermoreaction is observed at 0.5,6,12,24,48 hour, wherein there is skin adverse reaction in 0 example, the acne-removing composition described in explanation and Whelk-eliminating paste use safety.
the stability test of test example two, Whelk-eliminating paste
Do testing performance index to the Whelk-eliminating paste of embodiment 4, its test result is as follows:
1, heat-resistant stability investigates (40 DEG C × 30 days): qualified;
2, cold-resistant study on the stability (-10 DEG C × 30 days): qualified.
This test example two illustrates the Whelk-eliminating paste good stability of embodiment 4.
test example three, product effect assessment
One, given the test agent: the acne-removing composition of embodiment 1 ~ 3, comparative example 1; The Whelk-eliminating paste that embodiment 4 ~ 6 is obtained
Two, tested crowd
Sex number: female, 84 people; Man 56 people
Age: between 20 ~ 40 years old
Skin: face has obvious acne and small pox, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Grouping: be divided into 7 groups, often organize 20 people, female 12 people, male 8 people.
Method of testing: get appropriate given the test agent and be coated in clean affected part, every day 2 times, each 1 time sooner or later, 2 weeks on probation; Experimenter keeps good daily life system time and dietary habit in the trial employment period.The feedback of statistics experimenter after 2 weeks, concrete outcome sees the following form 1 ~ 7.
The test result of table 1 embodiment 1 acne-removing composition
The test result of table 2 embodiment 2 acne-removing composition
The test result of table 3 embodiment 3 acne-removing composition
The test result of table 4 comparative example 1 acne-removing composition
The test result of table 5 embodiment 4 acne-removing composition
The test result of table 6 embodiment 5 acne-removing composition
The test result of table 7 embodiment 6 acne-removing composition
(1) from table 1 ~ 4, the embodiment of the present invention 1 ~ 3 acne-removing composition obtains the accreditation of nearly all experimenter, it is effective that its anti-acne, acne removing print, pox flesh can be repaired simultaneously, namely the situations such as red swelling of the skin, coarse, fat secretion is vigorous are improved, reduce small pox regeneration, wherein the highest with the degree of recognition of the acne-removing composition of embodiment 1; Comparative example 1 has lacked some component compared with embodiment 1 ~ 3, and its effect, all not as good as embodiment 1 ~ 3, illustrates to there is synergism between each component of acne-removing composition of the present invention.
(2) from table 5 ~ 7, the embodiment of the present invention 4 ~ 6 Whelk-eliminating paste obtains the accreditation of nearly all experimenter equally, and its anti-acne, acne removing print, repair the effective of pox flesh, and wherein with embodiment 4 Whelk-eliminating paste best results, degree of recognition is the highest; Compared with acne-removing composition, the degree of recognition of Whelk-eliminating paste is higher, prove Whelk-eliminating paste anti-acne of the present invention, acne removing print, repair the effect of pox flesh more obviously, illustrate that Whelk-eliminating paste formula of the present invention can work in coordination with the effect that acne-removing composition of the present invention reaches anti-acne, acne removing print, reparation pox flesh better.
There is not people to occur allergic phenomena in whole experimenter simultaneously, all do not occur the situations such as skin pruritus, twinge, redness yet.
Above-described embodiment is illustrative principle of the present invention and effect thereof only, but not for limiting the present invention.Any person skilled in the art scholar all without prejudice under spirit of the present invention and category, can modify above-described embodiment or changes.Therefore, such as have in art usually know the knowledgeable do not depart from complete under disclosed spirit and technological thought all equivalence modify or change, must be contained by claim of the present invention.
Claims (8)
1. an acne-removing composition, is characterized in that, comprises following component: Butyrospermum parkii fruit fat, Cortex Phellodendri extract, black extract of willow bark, Herba portulacae extract, Folium perillae extract, Herba Centellae extract and Semen phaseoli radiati extract.
2. acne-removing composition as claimed in claim 1, it is characterized in that, described acne-removing composition is made up of the component of following weight portion: Butyrospermum parkii fruit 10 ~ 30 parts, fat, Cortex Phellodendri extract 2 ~ 8 parts, black extract of willow bark 2 ~ 8 parts, Herba portulacae extract 2 ~ 10 parts, Folium perillae extract 2 ~ 8 parts, Herba Centellae extract 2 ~ 8 parts and Semen phaseoli radiati extract 3 ~ 10 parts.
3. acne-removing composition as claimed in claim 2, it is characterized in that, described acne-removing composition is made up of the component of following weight portion: Butyrospermum parkii fruit 20 parts, fat, Cortex Phellodendri extract 5 parts, black extract of willow bark 6 parts, Herba portulacae extract 8 parts, Folium perillae extract 5 parts, Herba Centellae extract 5 parts and Semen phaseoli radiati extract 8 parts.
4. the application of the acne-removing composition as described in as arbitrary in claim 1 ~ 3 in preparation anti-acne skin care item.
5. a Whelk-eliminating paste, it is characterized in that, comprise the raw material of following weight percent meter: the arbitrary described acne-removing composition 2 ~ 8% of claim 1 ~ 3, cetearyl alcohol 3 ~ 5%, ethylhexyl palmitate 2 ~ 4%, polydimethylsiloxane 2 ~ 4%, glyceryl stearate 0.5 ~ 2%, PEG-100 stearate 0.5 ~ 2%, caprylic/capric triglyceride 1 ~ 3%, propylene glycol 1 ~ 3%, polyacrylamide 0.5 ~ 1.5%, polysorbate-60 1 ~ 1.5%, sorbitan stearate 0.5 ~ 1.5%, laurocapram 0.2 ~ 0.8%, PEG-20 methyl sesquistearate 0.2 ~ 0.8%, menthol 0.2 ~ 0.8%, Borneolum Syntheticum 0.1 ~ 0.3%, EDTA disodium 0.05 ~ 0.15%, methyl hydroxybenzoate 0.05 ~ 0.3%, propyl hydroxybenzoate 0.05 ~ 0.15% and water 70 ~ 80%.
6. Whelk-eliminating paste as claimed in claim 5, it is characterized in that, be made up of the raw material of following weight percent meter: the arbitrary described acne-removing composition 6% of claim 1 ~ 3, cetearyl alcohol 4%, ethylhexyl palmitate 3%, polydimethylsiloxane 3%, glyceryl stearate 1%, PEG-100 stearate 1%, caprylic/capric triglyceride 2%, propylene glycol 2%, polyacrylamide 1%, polysorbate-60 1.2%, sorbitan stearate 1%, laurocapram 0.6%, PEG-20 methyl sesquistearate 0.5%, menthol 0.5%, Borneolum Syntheticum 0.2%, EDTA disodium 0.1%, methyl hydroxybenzoate 0.2%, propyl hydroxybenzoate 0.1% and water 72.6%.
7. the preparation method of the Whelk-eliminating paste as described in as arbitrary in claim 5 ~ 6, is characterized in that, comprise the following steps:
S1, cetearyl alcohol, ethylhexyl palmitate, polydimethylsiloxane, glyceryl stearate, PEG-100 stearate, caprylic/capric triglyceride, polysorbate-60, sorbitan stearate, laurocapram, PEG-20 methyl sesquistearate, methyl hydroxybenzoate and propyl hydroxybenzoate are added in oil phase pot, be heated to 75 ~ 85 DEG C while stirring, and be stirred to material and dissolve completely, obtain material one, for subsequent use;
S2, EDTA disodium, water are added in aqueous phase pot, be stirred and heated to 80 ~ 85 DEG C, in suction reaction pot, then by material one suction, open homogenizing, after adding polyacrylamide homogenizing 5 ~ 10min, after insulated and stirred 15min, start cooling simultaneously, add propylene glycol, menthol, Borneolum Syntheticum, acne-removing composition stirring when 45 DEG C, obtain Whelk-eliminating paste.
8. the preparation method of Whelk-eliminating paste as claimed in claim 7, it is characterized in that, the mixing speed of described stirring is 40 ~ 50 revs/min.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510433429.4A CN105012479B (en) | 2015-07-22 | 2015-07-22 | A kind of acne-removing composition and its application and the Whelk-eliminating paste containing the acne-removing composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510433429.4A CN105012479B (en) | 2015-07-22 | 2015-07-22 | A kind of acne-removing composition and its application and the Whelk-eliminating paste containing the acne-removing composition |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105012479A true CN105012479A (en) | 2015-11-04 |
CN105012479B CN105012479B (en) | 2018-03-30 |
Family
ID=54403024
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510433429.4A Active CN105012479B (en) | 2015-07-22 | 2015-07-22 | A kind of acne-removing composition and its application and the Whelk-eliminating paste containing the acne-removing composition |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105012479B (en) |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105616522A (en) * | 2016-03-02 | 2016-06-01 | 广州千百度化妆品有限公司 | Traditional Chinese medicine acne cream |
CN107753379A (en) * | 2017-12-05 | 2018-03-06 | 佛山微赢电子商务有限公司 | It is a kind of effectively anti-acne to desalinate Whelk-eliminating paste of pockmark and preparation method thereof simultaneously |
CN108294992A (en) * | 2018-03-31 | 2018-07-20 | 佛山文森特知识产权服务有限公司 | A kind of acne-removing composition |
CN108434032A (en) * | 2018-04-27 | 2018-08-24 | 安婕妤化妆品科技股份有限公司 | A kind of anti-acne skin care item and preparation method thereof |
CN108938511A (en) * | 2018-10-16 | 2018-12-07 | 湖南诺泽生物科技有限公司 | The composition of natural plant extracts and the application in skin moisture-keeping product for resolving poxes |
CN105326730B (en) * | 2015-12-16 | 2018-12-25 | 广州市中通生化制品有限公司 | A kind of acne-removing composition and preparation method thereof containing Chinese herbal medicine extract |
WO2019136105A1 (en) * | 2018-01-02 | 2019-07-11 | Skinkick, Llc | Topical skin care compositions |
CN110051761A (en) * | 2019-06-12 | 2019-07-26 | 郑州植美堂生物科技有限公司 | Topical agent of acne-removing inflammation-diminishing and preparation method thereof |
CN110051548A (en) * | 2019-04-19 | 2019-07-26 | 广州市巨匠美容发展有限公司 | A kind of ferment enzyme Deacne pack and preparation method thereof |
CN111135280A (en) * | 2020-01-15 | 2020-05-12 | 威海盛朗生物科技有限公司 | A pharmaceutical composition, ointment and plaster for treating arthritis |
CN111743831A (en) * | 2020-06-24 | 2020-10-09 | 广州品赫生物科技有限公司 | Acne removing composition |
CN112006956A (en) * | 2020-09-04 | 2020-12-01 | 广州莱梧生物科技有限公司 | Acne-removing cream and preparation process thereof |
CN112107520A (en) * | 2020-10-22 | 2020-12-22 | 广州科盈化妆品有限公司 | Acne-removing composition and preparation method and application thereof |
CN112451453A (en) * | 2020-11-30 | 2021-03-09 | 重庆中佳信生物科技有限公司 | Bamboo extract acne-removing cream and preparation method thereof |
CN113116777A (en) * | 2021-04-14 | 2021-07-16 | 浙江目中明生物科技有限公司 | Acne removing composition and preparation method of acne removing cream thereof |
CN113995701A (en) * | 2021-11-06 | 2022-02-01 | 马丙生 | Composition for removing acne and acne marks and preparation method and application thereof |
CN115120537A (en) * | 2022-04-02 | 2022-09-30 | 广东机电职业技术学院 | Acne-removing, oil-controlling and anti-inflammatory multi-effect repair face cream and preparation method thereof |
CN115337252A (en) * | 2022-08-22 | 2022-11-15 | 广州药妆日用化工有限公司 | Acne-removing cream with acne-removing, inflammation-diminishing and skin-repairing effects and preparation method thereof |
CN117243834A (en) * | 2023-10-09 | 2023-12-19 | 广州百孚润化工有限公司 | Oil-control acne-removing composition with high octanoyl glycine content, and preparation method and application thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103622885A (en) * | 2013-09-13 | 2014-03-12 | 马应龙药业集团股份有限公司 | Skin caring composition having function of removing acne marks, preparation and preparation method of skin caring composition |
CN104188849A (en) * | 2014-08-07 | 2014-12-10 | 广州雅纯化妆品制造有限公司 | Mild and effective acne removing and oil control composition and preparation method thereof |
-
2015
- 2015-07-22 CN CN201510433429.4A patent/CN105012479B/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103622885A (en) * | 2013-09-13 | 2014-03-12 | 马应龙药业集团股份有限公司 | Skin caring composition having function of removing acne marks, preparation and preparation method of skin caring composition |
CN104188849A (en) * | 2014-08-07 | 2014-12-10 | 广州雅纯化妆品制造有限公司 | Mild and effective acne removing and oil control composition and preparation method thereof |
Non-Patent Citations (1)
Title |
---|
刘翠娥等: "清解汤治疗痤疮45例", 《河北中医》 * |
Cited By (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105326730B (en) * | 2015-12-16 | 2018-12-25 | 广州市中通生化制品有限公司 | A kind of acne-removing composition and preparation method thereof containing Chinese herbal medicine extract |
CN105616522A (en) * | 2016-03-02 | 2016-06-01 | 广州千百度化妆品有限公司 | Traditional Chinese medicine acne cream |
CN107753379A (en) * | 2017-12-05 | 2018-03-06 | 佛山微赢电子商务有限公司 | It is a kind of effectively anti-acne to desalinate Whelk-eliminating paste of pockmark and preparation method thereof simultaneously |
US20200384055A1 (en) * | 2018-01-02 | 2020-12-10 | Skinkick, Llc | Topical Skin Care Compositions |
WO2019136105A1 (en) * | 2018-01-02 | 2019-07-11 | Skinkick, Llc | Topical skin care compositions |
CN108294992A (en) * | 2018-03-31 | 2018-07-20 | 佛山文森特知识产权服务有限公司 | A kind of acne-removing composition |
CN108434032A (en) * | 2018-04-27 | 2018-08-24 | 安婕妤化妆品科技股份有限公司 | A kind of anti-acne skin care item and preparation method thereof |
CN108938511A (en) * | 2018-10-16 | 2018-12-07 | 湖南诺泽生物科技有限公司 | The composition of natural plant extracts and the application in skin moisture-keeping product for resolving poxes |
CN108938511B (en) * | 2018-10-16 | 2021-07-16 | 湖南诺泽生物科技有限公司 | Composition of natural plant extracts and application of composition in skin moisturizing and acne removing products |
CN110051548A (en) * | 2019-04-19 | 2019-07-26 | 广州市巨匠美容发展有限公司 | A kind of ferment enzyme Deacne pack and preparation method thereof |
CN110051761A (en) * | 2019-06-12 | 2019-07-26 | 郑州植美堂生物科技有限公司 | Topical agent of acne-removing inflammation-diminishing and preparation method thereof |
CN111135280A (en) * | 2020-01-15 | 2020-05-12 | 威海盛朗生物科技有限公司 | A pharmaceutical composition, ointment and plaster for treating arthritis |
CN111743831A (en) * | 2020-06-24 | 2020-10-09 | 广州品赫生物科技有限公司 | Acne removing composition |
CN112006956A (en) * | 2020-09-04 | 2020-12-01 | 广州莱梧生物科技有限公司 | Acne-removing cream and preparation process thereof |
CN112107520A (en) * | 2020-10-22 | 2020-12-22 | 广州科盈化妆品有限公司 | Acne-removing composition and preparation method and application thereof |
CN112451453A (en) * | 2020-11-30 | 2021-03-09 | 重庆中佳信生物科技有限公司 | Bamboo extract acne-removing cream and preparation method thereof |
CN113116777A (en) * | 2021-04-14 | 2021-07-16 | 浙江目中明生物科技有限公司 | Acne removing composition and preparation method of acne removing cream thereof |
CN113995701A (en) * | 2021-11-06 | 2022-02-01 | 马丙生 | Composition for removing acne and acne marks and preparation method and application thereof |
CN113995701B (en) * | 2021-11-06 | 2023-07-07 | 南京苗坊净颜生物科技有限公司 | Composition for removing acnes and acne marks as well as preparation method and application thereof |
CN115120537A (en) * | 2022-04-02 | 2022-09-30 | 广东机电职业技术学院 | Acne-removing, oil-controlling and anti-inflammatory multi-effect repair face cream and preparation method thereof |
CN115337252A (en) * | 2022-08-22 | 2022-11-15 | 广州药妆日用化工有限公司 | Acne-removing cream with acne-removing, inflammation-diminishing and skin-repairing effects and preparation method thereof |
CN117243834A (en) * | 2023-10-09 | 2023-12-19 | 广州百孚润化工有限公司 | Oil-control acne-removing composition with high octanoyl glycine content, and preparation method and application thereof |
CN117243834B (en) * | 2023-10-09 | 2024-04-26 | 广州百孚润化工有限公司 | Oil-control acne-removing composition with high octanoyl glycine content, and preparation method and application thereof |
Also Published As
Publication number | Publication date |
---|---|
CN105012479B (en) | 2018-03-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105012479A (en) | Acne treatment composition and application thereof and acne treatment cream containing acne treatment composition | |
CN109157450B (en) | Acne-removing essence | |
CN106361599A (en) | Multi-vegetable-oil-containing infantile eczema care cream | |
CN108969446B (en) | Infant anti-chap skin care composition for enhancing skin barrier function and preparation method thereof | |
CN103520053B (en) | Hair and body bathing powder | |
CN109157451B (en) | Acne-removing facial cleanser | |
CN109288764B (en) | Hydrolat spray and preparation method thereof | |
CN108969429A (en) | A kind of anti-acne essence | |
CN105106660B (en) | A kind of kibe ointment and preparation method thereof of the easypro trace of skin care | |
CN105536027A (en) | Scar treatment strip capable of lowering tissue tension and preparation method thereof | |
CN109260075B (en) | Acne-removing conditioning water | |
CN102846503A (en) | Refreshing, anti-dandruff, nourishing and healthful shampoo and preparation method thereof | |
CN107308094A (en) | A kind of salubrious oil-control fermentation Chinese wolfberry fruit liquid level film and preparation method thereof | |
CN117045523A (en) | High-content azelaic acid composition and preparation method thereof | |
CN115414299B (en) | A soothing and repairing freeze-dried spray | |
CN108186531A (en) | A kind of generating hair essence liquid and preparation method and application | |
CN108295022B (en) | Acne-removing composition and preparation method thereof | |
CN109157470A (en) | A kind of pox-dispelling function whitening skin-protection cream and preparation method thereof | |
CN109125165A (en) | A kind of compact face of repairing is releived facial mask and preparation method thereof | |
CN105267119A (en) | Nourishing, moisturizing and injury-repairing lip pomade and preparation method thereof | |
CN108938514B (en) | Skin-clearing acne-removing liquid and preparation method thereof | |
CN103405364B (en) | Traditional Chinese medicine composition with whitening effect, and preparation method and application thereof | |
KR20210043319A (en) | A serum-type cosmetic composition containing a natural extract compound | |
CN113425642B (en) | Eye care composition | |
CN109010520A (en) | A kind of ointment and preparation method thereof for treating dark sore |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB02 | Change of applicant information |
Address after: Huadu District, Guangdong city of Guangzhou province 510880 Flower Town Qiyuan Road No. 28 Applicant after: Guangzhou Kema biotechnology Polytron Technologies Inc Address before: Hua Town, Huadu District, Guangdong Province, 510880 Avenue, Guangzhou City Applicant before: Kerma (unit of kinetic energy) bio tech ltd, Guangzhou |
|
CB02 | Change of applicant information | ||
CB03 | Change of inventor or designer information |
Inventor after: Li Hongjun Inventor after: He Zhiqing Inventor before: Li Hongjun |
|
CB03 | Change of inventor or designer information | ||
GR01 | Patent grant | ||
GR01 | Patent grant |