CN104983446B - A kind of electronic placenta card punch - Google Patents
A kind of electronic placenta card punch Download PDFInfo
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- CN104983446B CN104983446B CN201510238898.0A CN201510238898A CN104983446B CN 104983446 B CN104983446 B CN 104983446B CN 201510238898 A CN201510238898 A CN 201510238898A CN 104983446 B CN104983446 B CN 104983446B
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Abstract
本发明涉及一种电动胎盘打孔器，所述电动胎盘打孔器包括打孔器本体、锁紧套、力矩调节螺母、电动支架、工作压杆、换向开关、吊环、电源插头；所述电动支架中设有电机；所述电机的输出轴与打孔器本体的一端建立连接，其连接处设有锁紧套；所述锁紧套外圆周面装配有力矩调节螺母；所述电动支架另一端连接工作压杆、换向开关、吊环、电源插头；所述打孔器本体包括采样段、过渡段、连接段；所述采样段近端的外圆周面上还设有采样孔。其优点表现在：本发明的一种电动胎盘打孔器，其操作方便，效率高，减少操作时间，降低蛋白质等生物信息的降解流失；使用安全，创伤小，不会损伤胎盘组织和羊膜、绒毛。
The invention relates to an electric placenta puncher, which includes a puncher body, a locking sleeve, a torque adjustment nut, an electric bracket, a working pressure rod, a reversing switch, a suspension ring, and a power plug; A motor is provided in the electric support; the output shaft of the motor is connected to one end of the punch body, and a locking sleeve is provided at the connection; the outer peripheral surface of the locking sleeve is equipped with a torque adjustment nut; the electric support The other end is connected with a working pressure rod, a reversing switch, a suspension ring, and a power plug; the puncher body includes a sampling section, a transition section, and a connecting section; sampling holes are also provided on the outer peripheral surface of the proximal end of the sampling section. Its advantages are as follows: the electric placenta puncher of the present invention is easy to operate, high in efficiency, reduces operating time, and reduces the degradation and loss of biological information such as protein; it is safe to use, has small trauma, and will not damage placental tissue and amniotic membrane, fluff.
Description
技术领域technical field
本发明涉及医疗器械技术领域，具体地说，是一种电动胎盘打孔器。The invention relates to the technical field of medical instruments, in particular to an electric placenta puncher.
背景技术Background technique
胎盘是重要的稀缺生物样本。胎盘作为妊娠期连接母胎的独特器官，具有重要的功能：1、在母亲和胎儿异体移植物之间提供一个免疫界面；2、在母胎间构建一个营养、代谢废物转运平台；3、作为产生多种多肽和甾体类激素的来源，通过这些多肽和甾体激素来影响胎儿、胎盘以及母亲的相关代谢和发育。胎盘维系正常妊娠，和孕母和子代的围产期和远期安全密切相关。胎盘中的细胞间紧密连接参与形成胎盘屏障，胎盘屏障具有维持母胎稳态的重要功能，如转运水分、营养物质及代谢产物等。适宜氧气浓度对细胞屏障的形成和维持具有十分重要的作用，同时也是维持妊娠期正常滋养层细胞功能的必要条件。妊娠中晚期缺氧状态被认为是影响胎盘形态和功能的最关键因素。子宫胎盘血流量减少、宫内氧气供应和营养状态下降等因素，可能改变胎盘滋养层细胞的生物学特性，造成胎盘结构、功能改变。在这种情况下，胎盘通过改变相关蛋白表达或相关基因表观遗传修饰来适应这些改变，满足胎儿发育需求，发挥其代偿功能。围生期母婴的病理结局与胎盘功能有着密切的关联。因此研究胎盘的组织具有重要的意义。Placenta is an important and scarce biological sample. As a unique organ connecting the mother and the fetus during pregnancy, the placenta has important functions: 1. Provide an immune interface between the mother and the fetal allograft; 2. Build a transport platform for nutrition and metabolic waste between the mother and the fetus; It is the source of a variety of polypeptides and steroid hormones, which affect the metabolism and development of the fetus, placenta and mother through these polypeptides and steroid hormones. The placenta maintains a normal pregnancy and is closely related to the perinatal and long-term safety of the mother and offspring. The intercellular tight junctions in the placenta participate in the formation of the placental barrier, which has important functions in maintaining maternal-fetal homeostasis, such as transporting water, nutrients and metabolites. Appropriate oxygen concentration plays a very important role in the formation and maintenance of cell barriers, and is also a necessary condition for maintaining normal trophoblast cell function during pregnancy. Hypoxia in the second and third trimesters of pregnancy is considered to be the most critical factor affecting the morphology and function of the placenta. Factors such as decreased uterine placental blood flow, decreased intrauterine oxygen supply and nutritional status may change the biological characteristics of placental trophoblast cells, resulting in changes in placental structure and function. In this case, the placenta adapts to these changes by changing the expression of related proteins or the epigenetic modification of related genes to meet the needs of fetal development and exert its compensatory function. The pathological outcomes of perinatal mothers and infants are closely related to placental function. Therefore, it is of great significance to study the organization of the placenta.
然而目前所有胎盘取材无特殊器械，仅有剪刀和刀片等器械，这些器械操作速度慢，容易造成胎盘病理结构的破坏，随着时间的浪费蛋白降解，影响生物学研究。However, there are currently no special equipment for all placental material collection, only scissors and blades and other equipment. These equipment are slow in operation and are likely to cause damage to the pathological structure of the placenta. Over time, protein degradation affects biological research.
目前关于胎盘取材主要存在以下缺陷：1、胎盘的结构特殊,取材困难,血供丰富，因此采用胎盘组织取材时,为了满足不同的科研需要，在不同的部位进行完整的取材非常困难；2.既往用剪刀和手术刀片等方法，定位困难，破坏胎盘组织的完整结构，分层困难，操作时间长；3、胎盘取材时，对胎盘组织损伤大。At present, there are mainly the following defects in the placenta sampling: 1. The structure of the placenta is special, it is difficult to obtain materials, and the blood supply is rich. Therefore, when using placenta tissue to obtain materials, it is very difficult to obtain complete materials from different parts in order to meet different scientific research needs; 2. In the past, methods such as scissors and surgical blades were used, which were difficult to locate, destroyed the complete structure of the placenta tissue, difficult to delaminate, and took a long time to operate; 3. When the placenta was taken, the damage to the placenta tissue was large.
综上所述，亟需一种方便快捷地获得胎盘组织，保证生物样本的完整性，减少胎盘组织损伤，方便取材的电动胎盘打孔器，而关于这种电动胎盘打孔器目前还未见报道。In summary, there is an urgent need for an electric placenta puncher that can obtain placental tissue quickly and conveniently, ensure the integrity of biological samples, reduce damage to placental tissue, and facilitate the extraction of materials. However, there is no such electric placenta puncher yet. reports.
发明内容Contents of the invention
本发明的目的是针对现有技术中的不足，提供一种方便快捷地获得胎盘组织，保证生物样本的完整性，减少胎盘组织损伤，方便取材的电动胎盘打孔器。The object of the present invention is to address the deficiencies in the prior art, and provide an electric placenta puncher that can obtain placental tissue conveniently and quickly, ensure the integrity of biological samples, reduce damage to the placental tissue, and facilitate material extraction.
为实现上述目的，本发明采取的技术方案是：For realizing above-mentioned object, the technical scheme that the present invention takes is:
一种电动胎盘打孔器，所述电动胎盘打孔器包括打孔器本体、锁紧套、力矩调节螺母、电动支架、工作压杆、换向开关、吊环、电源插头；所述电动支架中设有电机；所述电机的输出轴与打孔器本体的一端建立连接，其连接处设有锁紧套；所述锁紧套外圆周面装配有力矩调节螺母；所述电动支架另一端连接工作压杆、换向开关、吊环、电源插头；所述打孔器本体包括采样段、过渡段、连接段；所述采样段近端的外圆周面上还设有采样孔。An electric placenta puncher, the electric placenta puncher includes a puncher body, a locking sleeve, a torque adjustment nut, an electric bracket, a working pressure bar, a reversing switch, a suspension ring, and a power plug; A motor is provided; the output shaft of the motor is connected to one end of the punch body, and a locking sleeve is provided at the connection; the outer peripheral surface of the locking sleeve is equipped with a torque adjustment nut; the other end of the electric support is connected to Working pressure rod, reversing switch, suspension ring, power plug; the puncher body includes a sampling section, a transition section, and a connecting section; a sampling hole is also provided on the outer peripheral surface of the proximal end of the sampling section.
进一步地，所述的采样段、过渡段、连接段是一次整体成型的。Further, the sampling section, the transition section and the connecting section are integrally formed at one time.
进一步地，所述的过渡段一端连接采样段，另一端与连接段建立连接。Further, one end of the transition section is connected to the sampling section, and the other end is connected to the connection section.
进一步地，所述的采样段为中空结构，其中采样段远端为开口结构，采样段近端为封闭结构。Further, the sampling section is a hollow structure, wherein the distal end of the sampling section is an open structure, and the proximal end of the sampling section is a closed structure.
进一步地，所述的采样孔与采样段的内部空腔相通；所述采样孔呈梯形。Further, the sampling hole communicates with the internal cavity of the sampling section; the sampling hole is trapezoidal.
进一步地，所述的连接段设有限位螺钉和装配段。Further, the connecting section is provided with a limit screw and an assembly section.
进一步地，所述限位螺钉垂直贯穿在连接段中。Further, the limit screw runs vertically through the connecting section.
进一步地，所述装配段呈哑铃形。Further, the assembly section is in the shape of a dumbbell.
进一步地，所述打孔器本体的采样段为圆柱形结构。Further, the sampling section of the punch body is a cylindrical structure.
本发明优点在于：The present invention has the advantage that:
1、本发明的一种电动胎盘打孔器，其操作方便，效率高，减少操作时间，降低蛋白质等生物信息的降解流失；使用安全，创伤小，不会损伤胎盘组织和羊膜、绒毛；1. An electric placenta puncher of the present invention has the advantages of convenient operation, high efficiency, reduced operating time, and reduced degradation and loss of biological information such as protein; it is safe to use, has little trauma, and will not damage placental tissue, amniotic membrane, and villi;
2、通过打孔器本体与电动支架有机配合，在胎盘取材时，根据脐带与边缘的距离任意取点，可根据研究目的对取出组织横向分解，分离胎盘的母面、子面等亚组织，并根据研究的后续方法(蛋白/基因等)进行不同的手续；2. Through the organic cooperation of the puncher body and the electric support, when the placenta is taken, any point can be selected according to the distance between the umbilical cord and the edge, and the removed tissue can be decomposed horizontally according to the research purpose, and the sub-tissues such as the mother surface and the child surface of the placenta can be separated. And carry out different procedures according to the follow-up method of the research (protein/gene, etc.);
3、打孔器本体的转速大小可以控制，减少胎盘室温放置时间，保证胎盘样本的完整性，增加实验的一致性和可重复性，为揭开母胎之谜提供可能，在妇科、产科、新生儿科、儿科、围产医学、外科等研究的临床和基础研究中均大有用处；3. The speed of the punch body can be controlled, which can reduce the placenta room temperature storage time, ensure the integrity of the placenta sample, increase the consistency and repeatability of the experiment, and provide the possibility to uncover the mystery of the mother and fetus. Useful in clinical and basic research in pediatrics, pediatrics, perinatal medicine, surgery, etc.;
4、不同的胎盘组织部位和组织结构，制定了不同的转动打孔器本体转速和大小，满足胎盘生物样本的完整性及可利用性；4. Different parts and structures of the placenta, different rotation speeds and sizes of the rotary puncher body are formulated to meet the integrity and availability of placental biological samples;
5、打孔器本体在换向开关的作用下，可顺时针旋转打孔取样和逆时针旋转打孔取样，取样打孔方便，避免胎盘病理结构破坏。5. Under the action of the reversing switch, the punch body can rotate clockwise for sampling and counterclockwise for sampling, which is convenient for sampling and drilling, and avoids the destruction of placental pathological structure.
附图说明Description of drawings
附图1是本发明的一种电动胎盘打孔器结构示意图。Accompanying drawing 1 is a kind of electric placenta perforator structure schematic diagram of the present invention.
附图2是本发明的一种电动胎盘打孔器中的打孔器本体正面结构示意图。Accompanying drawing 2 is a schematic diagram of the front structure of the punch body in an electric placenta punch according to the present invention.
附图3是本发明的一种电动胎盘打孔器中的打孔器本体反面结构示意图。Accompanying drawing 3 is a schematic diagram of the reverse structure of the punch body in an electric placenta punch according to the present invention.
具体实施方式Detailed ways
下面结合附图对本发明提供的具体实施方式作详细说明。The specific embodiments provided by the present invention will be described in detail below in conjunction with the accompanying drawings.
附图中涉及的附图标记和组成部分如下所示：The reference signs and components involved in the accompanying drawings are as follows:
1.打孔器本体 11.采样段1. Hole punch body 11. Sampling section
12.过渡段 13.连接段12. Transition section 13. Connection section
14.采样孔 15.限位螺钉14. Sampling hole 15. Limit screw
16.装配段 2.锁紧套16. Assembly section 2. Locking sleeve
3.力矩调节螺母 4.电动支架3. Torque adjustment nut 4. Electric bracket
5.工作压杆 6.换向开关5. Working pressure rod 6. Reversing switch
7.吊环 8.电源插头7. Lifting ring 8. Power plug
实施例1Example 1
为了便于描述，以下描述使用了术语“近端”和“远端”，所述近端为距离医生操作较近的一端；所述远端为距离医生操作较远的一端。For the convenience of description, the following description uses the terms "proximal end" and "distal end". The proximal end is the end closer to the doctor's operation; the distal end is the end farther away from the doctor's operation.
请参照图1，图1是本发明的一种电动胎盘打孔器结构示意图。一种电动胎盘打孔器；所述电动胎盘打孔器包括打孔器本体1、锁紧套2、力矩调节螺母3、电动支架4、工作压杆5、换向开关6、吊环7、电源插头8；所述电动支架4中设有电机(图中未示出)；所述电机的输出轴与打孔器本体1的一端建立连接，其连接处设有锁紧套2；所述锁紧套2外圆周面装配有力矩调节螺母3；所述电动支架4另一端连接工作压杆5、换向开关6、吊环7、电源插头8。Please refer to FIG. 1 , which is a schematic structural view of an electric placenta puncher according to the present invention. An electric placenta puncher; the electric placenta puncher includes a puncher body 1, a locking sleeve 2, a torque adjustment nut 3, an electric bracket 4, a working pressure bar 5, a reversing switch 6, a suspension ring 7, a power supply A plug 8; a motor (not shown) is provided in the electric support 4; the output shaft of the motor is connected with one end of the puncher body 1, and a locking sleeve 2 is provided at the connection; the lock The outer peripheral surface of the tight sleeve 2 is equipped with a torque adjusting nut 3;
请参照图2，图2是本发明的一种电动胎盘打孔器中的打孔器本体正面结构示意图。所述打孔器本体1包括采样段11、过渡段12、连接段13；所述的采样段11、过渡段12、连接段13是一次整体成型的；所述的过渡段12一端连接采样段11，另一端与连接段13建立连接；所述的采样段11为中空结构，其中采样段11远端为开口结构，采样段11近端为封闭结构；所述采样段11近端的外圆周面上还设有采样孔14；所述的采样孔14与采样段11的内部空腔相通；所述采样孔14呈梯形。Please refer to FIG. 2 . FIG. 2 is a schematic diagram of the front structure of the punch body in an electric placenta punch according to the present invention. The punch body 1 includes a sampling section 11, a transition section 12, and a connecting section 13; the sampling section 11, the transition section 12, and the connecting section 13 are integrally formed at one time; one end of the transition section 12 is connected to the sampling section 11, the other end is connected with the connection section 13; the sampling section 11 is a hollow structure, wherein the far end of the sampling section 11 is an open structure, and the proximal end of the sampling section 11 is a closed structure; the outer circumference of the sampling section 11 near-end There is also a sampling hole 14 on the surface; the sampling hole 14 communicates with the inner cavity of the sampling section 11; the sampling hole 14 is trapezoidal.
请参照图3，图3是本发明的一种电动胎盘打孔器中的打孔器本体反面结构示意图。所述的连接段13设有限位螺钉15和装配段16；所述限位螺钉15垂直贯穿在连接段13中；所述装配段16呈哑铃形。Please refer to FIG. 3 . FIG. 3 is a schematic diagram of the reverse structure of the punch body in an electric placenta punch according to the present invention. The connection section 13 is provided with a limit screw 15 and an assembly section 16; the limit screw 15 vertically penetrates the connection section 13; the assembly section 16 is in the shape of a dumbbell.
需要说明的是：所述打孔器本体1的采样段11为圆柱形结构，采用对胎盘打孔的方式取材，胎盘组织样本容纳在采样段11圆柱形空腔结构中，整个取材过程无其它器械对采样段11内的胎盘组织损伤，与传统选用刀片和剪刀的器械取材相比，选用打孔器本体1对胎盘取材能保证胎盘组织的完整性，便于对胎盘组织分层，减少胎盘组织创伤；It should be noted that the sampling section 11 of the punch body 1 has a cylindrical structure, and samples are obtained by punching the placenta. The device damages the placental tissue in the sampling section 11. Compared with the traditional method of using blades and scissors, the use of the puncher body 1 pair of placental materials can ensure the integrity of the placental tissue, facilitate the stratification of the placental tissue, and reduce the risk of placental tissue damage. trauma;
所述的力矩调节螺母3可控制打孔器本体1力矩转动大小，其力矩调节螺母3顺时针旋转时，力矩增大，力矩调节螺母3逆时针旋转时，力矩减小，通过控制打孔器本体1转动力矩大小，以便在胎盘不同位置处使用不同力矩来打孔取材；The torque adjustment nut 3 can control the torque rotation of the hole punch body 1. When the torque adjustment nut 3 rotates clockwise, the torque increases, and when the torque adjustment nut 3 rotates counterclockwise, the torque decreases. The size of the rotating torque of the body 1, so that different torques can be used at different positions of the placenta to punch holes and collect materials;
所述的换向开关6可改变电机的正负极性，使得电机输出轴可顺时针旋转和逆时针旋转，而电机输出轴与打孔器本体1同轴线固定连接在一起的，其打孔器本体1可以顺时针旋转和逆时针旋转。优选地，换向开关6顺时针旋转时，打孔器本体1顺时针旋转，换向开关6逆时针旋转时，打孔器本体1逆时针旋转。在操作状态下，打孔器本体1在胎盘上周期性的换向打孔，使得胎盘取材更佳快速，避免随着时间的浪费蛋白降解，胎盘病理结构的破坏，影响生物学研究。因胎盘为蠕动组织，单方向的旋转打孔容易出现胎盘组织缠绕成死节；The reversing switch 6 can change the positive and negative polarity of the motor, so that the output shaft of the motor can rotate clockwise and counterclockwise, and the output shaft of the motor is fixedly connected with the coaxial line of the puncher body 1. The holer body 1 can rotate clockwise and counterclockwise. Preferably, when the reversing switch 6 rotates clockwise, the punch body 1 rotates clockwise, and when the reversing switch 6 rotates counterclockwise, the punch body 1 rotates counterclockwise. In the operating state, the punch body 1 periodically reverses and punches holes on the placenta, so that the placenta can be obtained more quickly, avoiding the degradation of protein and the destruction of the pathological structure of the placenta over time, which will affect the biological research. Because the placenta is a peristaltic tissue, it is easy to cause the placental tissue to wind up into dead joints when the unidirectional rotary drilling is performed;
所述的锁紧套2对打孔器本体1的连接段13具有锁紧的作用，防止打孔器本体1在外力作用下脱离；因打孔器本体1工作状态下为旋转运动，其打孔器本体1的连接段13产生剪切力，容易迫使打孔器本体1脱离。而锁紧套2的固定作用下，可保证其正常工作；The locking sleeve 2 has a locking effect on the connecting section 13 of the puncher body 1, preventing the puncher body 1 from breaking away under the action of external force; The connecting section 13 of the hole punch body 1 generates a shearing force, which easily forces the hole punch body 1 to break away. Under the fixing effect of the locking sleeve 2, it can ensure its normal operation;
所述的工作压杆5与电动支架4呈有夹角，使用状态下，向下按时，工作压杆5以电动支架4为支撑点，其端部向上抬高时与电源接通，操作简单，可随时控制工作状态；The working pressure bar 5 has an included angle with the electric support 4. When it is in use, when it is pressed down, the working pressure bar 5 takes the electric support 4 as a support point, and when its end is lifted upwards, it is connected to the power supply, and the operation is simple. , can control the working status at any time;
所述的吊环7用于连接平衡器，减少整个装置在旋转运动时发生抖动的程度；所述连接段13设有限位螺钉15，其作用辅助定位变电动支架4的位置；所述的连接段13设有哑铃形装配段16，使得打孔器本体1装配更佳紧凑；所述的电源插头8用于提供电源；The suspension ring 7 is used to connect the balancer to reduce the vibration of the whole device during rotational movement; the connecting section 13 is provided with a limit screw 15, which serves to assist in positioning the position of the variable electric support 4; the connecting section 13 is provided with a dumbbell-shaped assembly section 16, so that the puncher body 1 is assembled more compactly; the power plug 8 is used to provide power;
所述的采样孔14可用于辅助提取胎盘组织，避免胎盘组织在打孔器本体1中的采样段11的内部空腔发生堵塞，其梯形的采样孔14在采集胎盘组织时更佳省时省力。The sampling hole 14 can be used to assist in the extraction of placental tissue, avoiding the blockage of the placental tissue in the internal cavity of the sampling section 11 in the punch body 1, and the trapezoidal sampling hole 14 is more time-saving and labor-saving when collecting placental tissue. .
本发明的一种电动胎盘打孔器使用方法是：首先将各部件连接紧凑，接上电源插头8提供电源；然后启动工作压杆5工作；工作过程呈中，根据需要调节力矩调节螺母3至合适位置，以及换向开关6控制打孔器本体1顺时针旋转和逆时针旋转。A method of using the electric placenta puncher of the present invention is as follows: first, connect the components compactly, connect the power plug 8 to provide power; then start the working pressure bar 5 to work; during the working process, adjust the torque adjustment nut 3 to proper position, and the reversing switch 6 controls the punch body 1 to rotate clockwise and counterclockwise.
本发明的一种电动胎盘打孔器，其操作方便，效率高，减少操作时间，降低蛋白质等生物信息的降解流失；使用安全，创伤小，不会损伤胎盘组织和羊膜、绒毛；通过打孔器本体1与电动支架4有机配合，在胎盘取材时，可根据脐带与边缘的距离任意取点，根据研究目的对取出组织横向分解，分离胎盘的母面、子面等亚组织，并根据研究的后续方法(蛋白/基因等)进行不同的手续；通过力矩调节螺母3调节力矩大小，以便在胎盘不同位置处使用不同力矩来打孔取材，胎盘取材效率高；打孔器本体1的转速大小可以控制，减少胎盘室温放置时间，保证胎盘样本的完整性，增加实验的一致性和可重复性，为揭开母胎之谜提供可能，在妇科、产科、新生儿科、儿科、围产医学、外科等研究的临床和基础研究中均大有用处；不同的胎盘组织部位和组织结构，制定了不同的转动打孔器本体1转速和大小，满足胎盘生物样本的完整性及可利用性；打孔器本体1在换向开关6的作用下，可顺时针旋转打孔取样和逆时针旋转打孔取样，取样打孔方便，避免胎盘病理结构破坏。An electric placenta puncher of the present invention has the advantages of convenient operation, high efficiency, reduced operating time, and reduced degradation and loss of biological information such as protein; it is safe to use, has small trauma, and will not damage placental tissue, amniotic membrane, and villi; The device body 1 is organically coordinated with the electric support 4. When the placenta is taken, points can be randomly selected according to the distance between the umbilical cord and the edge. The follow-up method (protein/gene, etc.) carries out different procedures; the torque is adjusted through the torque adjustment nut 3, so that different torques can be used to punch holes at different positions of the placenta, and the placenta has high efficiency; the speed of the punch body 1 It can be controlled to reduce the placenta room temperature storage time, ensure the integrity of the placenta sample, increase the consistency and repeatability of the experiment, and provide the possibility to uncover the mystery of the mother and fetus. It is used in gynecology, obstetrics, neonatal, pediatrics, perinatal medicine, surgery It is very useful in both clinical and basic research of researches such as placenta; different placental tissue parts and tissue structures have formulated different rotation speeds and sizes of the rotary puncher body 1 to meet the integrity and availability of placental biological samples; punching Under the effect of the reversing switch 6, the device body 1 can rotate clockwise for sampling and counterclockwise for sampling, which is convenient for sampling and drilling, and avoids the destruction of placental pathological structure.
以上所述仅是本发明的优选实施方式，应当指出，对于本技术领域的普通技术人员，在不脱离本发明方法的前提下，还可以做出若干改进和补充，这些改进和补充也应视为本发明的保护范围。The above is only a preferred embodiment of the present invention, it should be pointed out that for those of ordinary skill in the art, without departing from the method of the present invention, some improvements and supplements can also be made, and these improvements and supplements should also be considered Be the protection scope of the present invention.
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| CN102365055A (en) * | 2009-01-27 | 2012-02-29 | 遗传技术有限公司 | Biological sampling device |
| WO2014027352A1 (en) * | 2012-08-16 | 2014-02-20 | Cath Med Ltd. | Apparatuses for steering catheters |
| CN104480533A (en) * | 2014-12-29 | 2015-04-01 | 黑龙江天晴干细胞股份有限公司 | Placenta stem cell bank construction method and placenta tissue resuscitation method |
| CN204744481U (en) * | 2015-05-12 | 2015-11-11 | 上海交通大学医学院附属新华医院 | Electronic placenta hole puncher |
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| US8323209B2 (en) * | 2008-06-06 | 2012-12-04 | Williams Iii John | Chorionic villus sampling catheter |
| US9259210B2 (en) * | 2010-05-06 | 2016-02-16 | Icahn School Of Medicine At Mount Sinai | Tissue sampling tool |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102365055A (en) * | 2009-01-27 | 2012-02-29 | 遗传技术有限公司 | Biological sampling device |
| WO2014027352A1 (en) * | 2012-08-16 | 2014-02-20 | Cath Med Ltd. | Apparatuses for steering catheters |
| CN104480533A (en) * | 2014-12-29 | 2015-04-01 | 黑龙江天晴干细胞股份有限公司 | Placenta stem cell bank construction method and placenta tissue resuscitation method |
| CN204744481U (en) * | 2015-05-12 | 2015-11-11 | 上海交通大学医学院附属新华医院 | Electronic placenta hole puncher |
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