CN104800583A - Preparation method of medicament for treating chronic cholecystitis - Google Patents
Preparation method of medicament for treating chronic cholecystitis Download PDFInfo
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- CN104800583A CN104800583A CN201510243045.6A CN201510243045A CN104800583A CN 104800583 A CN104800583 A CN 104800583A CN 201510243045 A CN201510243045 A CN 201510243045A CN 104800583 A CN104800583 A CN 104800583A
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- herba
- medicament
- radix
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- 239000003814 drug Substances 0.000 title claims abstract description 29
- 206010008617 Cholecystitis chronic Diseases 0.000 title claims abstract description 15
- 201000001352 cholecystitis Diseases 0.000 title claims abstract description 15
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 239000000203 mixture Substances 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 4
- 238000011282 treatment Methods 0.000 claims description 20
- 239000003826 tablet Substances 0.000 claims description 8
- 241000628997 Flos Species 0.000 claims description 6
- 240000002853 Nelumbo nucifera Species 0.000 claims description 6
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims description 6
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims description 6
- 244000184734 Pyrus japonica Species 0.000 claims description 6
- 244000269722 Thea sinensis Species 0.000 claims description 6
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 6
- 239000010931 gold Substances 0.000 claims description 6
- 229910052737 gold Inorganic materials 0.000 claims description 6
- 229940079593 drug Drugs 0.000 claims description 5
- 239000002775 capsule Substances 0.000 claims description 4
- 239000000706 filtrate Substances 0.000 claims description 3
- 239000012467 final product Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 239000007919 dispersible tablet Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 4
- 241001121892 Acer campbellii Species 0.000 abstract 1
- 244000274051 Cornus kousa Species 0.000 abstract 1
- 241000522190 Desmodium Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 241000998779 Hemisteptia lyrata Species 0.000 abstract 1
- 244000048199 Hibiscus mutabilis Species 0.000 abstract 1
- 235000003973 Hibiscus mutabilis Nutrition 0.000 abstract 1
- 241000581972 Leptochilus digitatus Species 0.000 abstract 1
- 244000061661 Orchis Species 0.000 abstract 1
- 241000776144 Parthenocissus himalayana Species 0.000 abstract 1
- 241001531051 Potentilla chinensis Species 0.000 abstract 1
- 240000000103 Potentilla erecta Species 0.000 abstract 1
- 235000016551 Potentilla erecta Nutrition 0.000 abstract 1
- 240000002257 Veronica linariifolia Species 0.000 abstract 1
- 235000006153 Veronica linariifolia Nutrition 0.000 abstract 1
- 241001317546 Wedelia prostrata Species 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 235000015092 herbal tea Nutrition 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 238000011474 orchiectomy Methods 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 description 6
- 238000003745 diagnosis Methods 0.000 description 5
- 210000000232 gallbladder Anatomy 0.000 description 5
- 238000002604 ultrasonography Methods 0.000 description 5
- 238000009606 cholecystography Methods 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 208000019790 abdominal distention Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 210000003489 abdominal muscle Anatomy 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000002192 cholecystectomy Methods 0.000 description 1
- 201000001883 cholelithiasis Diseases 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000026273 gall bladder development Effects 0.000 description 1
- 208000020694 gallbladder disease Diseases 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000002688 persistence Effects 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 210000004915 pus Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a preparation method of a medicament for treating chronic cholecystitis. The preparation method comprises the following steps of: taking 60 g of herba saussuseae japonicae, 50 g of parthenocissus himalayana, 50 g of colysis digitata, 50 g of cinquefoil, 45 g of assorted Chinese herbal tea, 40 g of potentilla chinensis, 40 g of desmodium heterocarpum, 30 g of himalayan maple, 30 g of veronica linariifolia, 30 g of orchis, 35 g of hibiscus mutabilis, 35 g of wedelia prostrata, 35 g of hemistepta lyrata, 30 g of dendrobenthamia japonica and 20 g of liquorice; adding 15, 000 ml of water; heating in a flask equipped with a condenser at a temperature of 90 DEG C for 6 hours, and filtering to obtain filter liquor. The medicament for treating the chronic cholecystitis disclosed in the invention is reasonable in composition, accurate in effect and quite suitable for large-scale popularization clinically.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of preparation method for the treatment of the medicament of chronic cholecystitis.
Background technology
Chronic cholecystitis is more common gallbladder disease, and sickness rate is higher.Normal and cholelithiasis merges and exists.But also have some to be non-lithogenous chronic cholecystitis, chronic cholecystitis common treatment method has: Drug therapy and operative treatment.Row cholecystectomy is the basic treatment of chronic cholecystitis, but operative treatment wound is large, and intentionally, liver, the serious disease such as lung or systemic conditions can not tolerate surgery, cannot carry out the treatment of performing the operation.Western medicine is large to other organ injury of the health such as liver, stomach.Current clinical multiple, need new medicine.
Summary of the invention
The object of this invention is to provide a kind of preparation method for the treatment of the medicament of chronic cholecystitis.
In order to realize object of the present invention, the invention provides a kind of preparation method for the treatment of the medicament of chronic cholecystitis, the method comprises the following steps: to get Herba Saussuseae Japonicae 60 grams, three-jaw gold dragon 50 grams, Radix parietariae micranthae 50 grams, 50 grams, cliff lotus, assorted Chinese medicine tea 45 grams, Radix Rubi Parvifolii 40 grams, raw 40 grams of mountain flower, moth set 30 grams, HERBA VERONICAE DILATATAE 30 grams, Herba Orchidis Latifoliae 30 grams, Flos Hibisci Mutabilis 35 grams, Herba Wedeliae Prostratae 35 grams, Herba Hemisteptae Lyratae 35 grams, Dendronenthamia japonica var.chinensis 30 grams and 20 grams, Radix Glycyrrhizae, add 15000 milliliters, water, heat 6 hours at 90 DEG C in the flask that condenser is housed, filter, filtrate and get final product.
The present invention also provides the purposes of compositions in the medicament of preparation treatment chronic cholecystitis, and it is made up by weight of following bulk drugs: Herba Saussuseae Japonicae 60 parts, three-jaw gold dragon 50 parts, Radix parietariae micranthae 50 parts, 50 parts, cliff lotus, assorted Chinese medicine tea 45 parts, Radix Rubi Parvifolii 40 parts, raw 40 parts of mountain flower, moth set 30 parts, HERBA VERONICAE DILATATAE 30 parts, Herba Orchidis Latifoliae 30 parts, Flos Hibisci Mutabilis 35 parts, Herba Wedeliae Prostratae 35 parts, Herba Hemisteptae Lyratae 35 parts, Dendronenthamia japonica var.chinensis 30 parts and 20 parts, Radix Glycyrrhizae.
Preferably, described medicament can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, capsule or decoction.
In the present compositions, Herba Saussuseae Japonicae, three-jaw gold dragon is monarch drug, and Radix parietariae micranthae, cliff lotus, assorted Chinese medicine tea, Radix Rubi Parvifolii, mountain flower life are ministerial drug, and moth tree, HERBA VERONICAE DILATATAE, Herba Orchidis Latifoliae, Flos Hibisci Mutabilis, Herba Wedeliae Prostratae, Herba Hemisteptae Lyratae, Dendronenthamia japonica var.chinensis are adjuvant drug, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, for making medicine.Various ingredient exerts synergism is to produce optimum efficiency.
Rationally, definite effect, is extremely suitable for large-scale promotion clinically to the medicament composition for the treatment of chronic cholecystitis of the present invention.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment decoction of the present invention
Get Herba Saussuseae Japonicae 60 grams, three-jaw gold dragon 50 grams, Radix parietariae micranthae 50 grams, 50 grams, cliff lotus, assorted Chinese medicine tea 45 grams, Radix Rubi Parvifolii 40 grams, raw 40 grams of mountain flower, moth set 30 grams, HERBA VERONICAE DILATATAE 30 grams, Herba Orchidis Latifoliae 30 grams, Flos Hibisci Mutabilis 35 grams, Herba Wedeliae Prostratae 35 grams, Herba Hemisteptae Lyratae 35 grams, Dendronenthamia japonica var.chinensis 30 grams and 20 grams, Radix Glycyrrhizae, add 15000 milliliters, water, heat 6 hours at 90 DEG C in the flask that condenser is housed, filter, filtrate and get final product.
Experimental example
Diagnostic criteria.
Draft with reference to Ministry of Public Health " new Chinese medicine guideline of clinical investigations ": 1. persistence upper right abdomen dull pain or sense of discomfort, pain can be radiated by dorso-humeral region to the right; 2. have the indigestion symptoms such as nauseating, belch, acid regurgitation, abdominal distention and scorching hot, the postemphasis of feed greasy food, and the course of disease is long, the state of an illness is through having acute attack and alleviating the feature replaced; 3. gallbladder area is touched a tender spot obviously, upper right tension of abdominal muscle, and Murphy's sign is positive; 4. the visible thickening of capsule wall of gallbladder of B ultrasonic, gallbladder reduces or is out of shape, and gallbladder contraction function is bad, or gallbladder development is thin etc.
Selector close standard of stating patient 150 example, wherein women 80 example, male 70 example, age 29-58 year, average 41 years old.
Decoction obtained in embodiment is used to treat, one day twice, oral 150 milliliters at every turn, treatment 50 days continuously.
Curative effect determinate standard
1. cure: Clinical symptom and sign disappears, ultrasound diagnosis or cholecystography recover normal, observe half a year without recurrence; 2. effective: symptom and sign disappears substantially, ultrasound diagnosis or cholecystography obviously change; 3. invalid: treatments period sings and symptoms alleviates or without improvement, recurs again after stopping treatment.
Result
Through treatment, find that all patients Clinical symptom and sign disappears, ultrasound diagnosis or cholecystography recover normal, observe half a year after the treatment without recurrence, therefore all meet the curative effect determinate standard of healing.
Model case
Fu, female, 42 years old, government civilian, the right flank distending pain of patient, felt sick tending to vomit January, and companion's abdominal distention coughs up gas, and stool matter is glued not well, once a day (without mucus, pus and blood).Ultrasound diagnosis: gallbladder 7.7cm × 3.8cm, wall thickness 0.9cm is fuzzy in capsule.Decoction obtained in embodiment is used to treat, one day twice, oral 150 milliliters at every turn, treatment 50 days continuously.After treatment, patient clinical symptom and sign disappears, and ultrasound diagnosis or cholecystography recover normal, observes half a year after the treatment without recurrence.
Claims (3)
1. treat the preparation method of the medicament of chronic cholecystitis for one kind, the method comprises the following steps: to get Herba Saussuseae Japonicae 60 grams, three-jaw gold dragon 50 grams, Radix parietariae micranthae 50 grams, 50 grams, cliff lotus, assorted Chinese medicine tea 45 grams, Radix Rubi Parvifolii 40 grams, raw 40 grams of mountain flower, moth set 30 grams, HERBA VERONICAE DILATATAE 30 grams, Herba Orchidis Latifoliae 30 grams, Flos Hibisci Mutabilis 35 grams, Herba Wedeliae Prostratae 35 grams, Herba Hemisteptae Lyratae 35 grams, Dendronenthamia japonica var.chinensis 30 grams and 20 grams, Radix Glycyrrhizae, add 15000 milliliters, water, heat 6 hours at 90 DEG C in the flask that condenser is housed, filter, filtrate and get final product.
2. the purposes of compositions in the medicament of preparation treatment chronic cholecystitis, it is characterized in that, it is made up by weight of following bulk drugs: Herba Saussuseae Japonicae 60 parts, three-jaw gold dragon 50 parts, Radix parietariae micranthae 50 parts, 50 parts, cliff lotus, assorted Chinese medicine tea 45 parts, Radix Rubi Parvifolii 40 parts, raw 40 parts of mountain flower, moth set 30 parts, HERBA VERONICAE DILATATAE 30 parts, Herba Orchidis Latifoliae 30 parts, Flos Hibisci Mutabilis 35 parts, Herba Wedeliae Prostratae 35 parts, Herba Hemisteptae Lyratae 35 parts, Dendronenthamia japonica var.chinensis 30 parts and 20 parts, Radix Glycyrrhizae.
3. purposes according to claim 2, is characterized in that, described medicament can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, capsule or decoction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510243045.6A CN104800583A (en) | 2015-05-13 | 2015-05-13 | Preparation method of medicament for treating chronic cholecystitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510243045.6A CN104800583A (en) | 2015-05-13 | 2015-05-13 | Preparation method of medicament for treating chronic cholecystitis |
Publications (1)
| Publication Number | Publication Date |
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| CN104800583A true CN104800583A (en) | 2015-07-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510243045.6A Pending CN104800583A (en) | 2015-05-13 | 2015-05-13 | Preparation method of medicament for treating chronic cholecystitis |
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| Country | Link |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101700381A (en) * | 2009-11-12 | 2010-05-05 | 张国营 | Pill for healing hepatitis B and softening liver |
| CN104189654A (en) * | 2014-09-13 | 2014-12-10 | 吕银兰 | Traditional Chinese medicine granule for treating anorexia |
-
2015
- 2015-05-13 CN CN201510243045.6A patent/CN104800583A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101700381A (en) * | 2009-11-12 | 2010-05-05 | 张国营 | Pill for healing hepatitis B and softening liver |
| CN104189654A (en) * | 2014-09-13 | 2014-12-10 | 吕银兰 | Traditional Chinese medicine granule for treating anorexia |
Non-Patent Citations (1)
| Title |
|---|
| 裴英: "《治疗慢性胆囊炎》", 《陕西中医》 * |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| EXSB | Decision made by sipo to initiate substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150729 |