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CN104800537A - Traditional Chinese medicine composition for treating alopecia with hair-blacking function and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating alopecia with hair-blacking function and preparation method thereof Download PDF

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CN104800537A
CN104800537A CN201510240959.7A CN201510240959A CN104800537A CN 104800537 A CN104800537 A CN 104800537A CN 201510240959 A CN201510240959 A CN 201510240959A CN 104800537 A CN104800537 A CN 104800537A
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谭树华
聂娜
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Beijing Pushian Biotechnology Co ltd
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Hunan University of Science and Technology
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Abstract

本发明属于中药技术领域,具体涉及一种治疗脱发并具有乌发功能的中药组合物及其制备方法。所述的中药组合物包括内服制剂中药组合物和外用中药组合物。本发明根据中医理论和营养均衡原理,经过多年实践研究,精选出各原料药及其配比,并采用内服外用相结合的服药方式,达到治疗脱发并具有乌发功能效果,并且使头发更加乌黑亮泽,效果显著,具有标本兼治、效果好,见效快,成本低,使用方便、无毒副作用的优点。The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating hair loss and having the function of blackening hair and a preparation method thereof. The traditional Chinese medicine composition includes a traditional Chinese medicine composition for internal use and a traditional Chinese medicine composition for external use. According to the theory of traditional Chinese medicine and the principle of nutritional balance, the present invention selects various raw materials and their proportions after years of practical research, and adopts a combination of oral administration and external administration, so as to treat hair loss and have the effect of blackening hair, and make hair more healthy. It is black and glossy, with remarkable effect, and has the advantages of treating both symptoms and root causes, good effect, quick effect, low cost, convenient use and no side effects.

Description

一种治疗脱发并具有乌发功能的中药组合物及其制备方法A traditional Chinese medicine composition for treating hair loss and having the function of blackening hair and its preparation method

技术领域technical field

本发明属于中药技术领域,具体涉及一种治疗脱发并具有乌发功能的中药组合物及其制备方法。The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating hair loss and having the function of blackening hair and a preparation method thereof.

背景技术Background technique

近年来我国脱发白发症状有不断加剧的趋势,尤以男性脱发白发更为普遍,并出现了低龄化的势头。有资料表明,30岁以下男性中有半数以上都受到过脱发的困扰。根据城市抽样调查统计,我国中年人(35~59岁)白发、脱发发病率高达45.7%。In recent years, the symptoms of hair loss and white hair in our country have been increasing, especially in men with hair loss and white hair, and there is a trend of younger age. According to data, more than half of men under the age of 30 have suffered from hair loss. According to urban sampling survey statistics, the incidence rate of gray hair and hair loss among middle-aged people (35-59 years old) in my country is as high as 45.7%.

脱发是一种常见的皮肤病,可分为脂溢性脱发(又称脂秃、早秃)斑秃、全秃等。常见的脱发大多为脂溢性脱发(占脱发患者95%以上),其症状为患者头皮脂肪过量溢出,导致头发油腻潮湿,有时还伴有头皮搔痒等炎症。白发是衰老的生理变化之一,一般人到40岁以后毛发自然地逐渐由黑变白。中医认为肝藏血,发为血之余,肾主骨生髓,其荣在发,血气盛则肾气强,肾气强骨髓充满,毛发黑而有光泽,血气虚则肾气弱,血气不能行,发则枯黄无泽而脱落,故认为脱发、白发的形成与肝肾不足,血气虚弱有关。同时,人受七情内伤、情志抑郁、劳心伤脾、影响血气运行不畅而导致气滞血瘀,毛发失去营养而脱落,这与现代医学研究的机体内分泌与免疫紊乱失调、精神创伤与过度紧张、血管及血液循环障碍等因素,导致毛发营养障碍而脱发、白发的观点一致。脱发、白发不但与头发本身的病变有关,也受遗传、健康、营养不均衡、微量元素缺乏、不良饮食习惯和激素水平等多种因素的影响,而且与精神因素、内分泌因素、内脏器官疾病、药物、多种致病菌的感染等有关。Alopecia is a kind of common dermatosis, can be divided into seborrheic alopecia (also known as seborrheic alopecia, premature bald) alopecia areata, total alopecia etc. Common alopecia is seborrheic alopecia mostly (accounting for more than 95% of alopecia patients), and its symptom is that patient's scalp fat overflows excessively, causes hair greasy moist, also with inflammations such as scalp itching sometimes. White hair is one of the physiological changes of aging. After the age of 40, most people's hair gradually changes from black to white naturally. Traditional Chinese medicine believes that the liver stores blood, and the hair is the rest of the blood. The kidney governs the bone and marrow, and its glory is in the hair. If the blood qi is strong, the kidney qi will be strong. If the kidney qi is strong, the bone marrow will be full, and the hair will be black and shiny. If it can't be done, the hair will be yellow and lusterless and fall off. Therefore, it is believed that the formation of hair loss and gray hair is related to the deficiency of liver and kidney and the weakness of blood qi. At the same time, people suffer from internal injuries of the seven emotions, depression of emotions, fatigue of the mind and spleen, and poor circulation of blood and qi, resulting in qi stagnation and blood stasis, and hair loss due to loss of nutrition. Excessive tension, blood vessels and blood circulation disorders and other factors lead to trichotrophic disorders and hair loss, white hair. Hair loss and gray hair are not only related to the lesions of the hair itself, but also affected by various factors such as heredity, health, nutritional imbalance, lack of trace elements, bad eating habits and hormone levels, and are also related to mental factors, endocrine factors, internal organ diseases, etc. , drugs, infection with a variety of pathogenic bacteria, etc.

现代医学研究认为,白发主要由于毛发黑色素形成减少,黑色素细胞合成色素颗粒功能减弱,酪氨酸酶的活动减低所致。出现白发与精神因素和遗传因素有关,精神因素可使供应头发的血管发生挛缩,使头发根部的毛乳头制造黑色素的功能发生障碍,或者是虽产生了黑色素,但输入毛干的渠道受阻。也有少数人的白发是由于肝肾气血亏损或某种特殊疾病及营养元素缺乏等原因引起的。治疗以活血化瘀、舒通经脉、滋养毛根、促进毛囊黑色素的再生和利用,及滋补肝肾以增强毛发的生长功能为原则。近年来临床检测表明,脱发、白发患者血清中内皮素(ET)含量明显高于正常人。这种能够引起局部血管强烈发缩痉挛而致首部供血减少的物质,可导致毛发枯竭脱落或变白。头发血流检测也证实,脱发患者头皮不仅有组织和医学改变,还存在血流阻力高,血流总量少,有效灌注减少的异常现象。Modern medical research believes that gray hair is mainly due to the reduction of hair melanin formation, the weakening of the function of melanocytes to synthesize pigment granules, and the reduction of tyrosinase activity. The occurrence of gray hair is related to mental factors and genetic factors. Mental factors can cause the blood vessels supplying hair to contract, and make the dermal papilla at the root of the hair produce melanin. There are also a few people whose gray hair is caused by the loss of liver and kidney qi and blood or some special disease and lack of nutritional elements. The treatment is based on the principle of promoting blood circulation to remove blood stasis, relaxing meridians, nourishing hair roots, promoting the regeneration and utilization of melanin in hair follicles, and nourishing liver and kidney to enhance hair growth function. Clinical tests in recent years have shown that the content of endothelin (ET) in the serum of patients with alopecia and gray hair is significantly higher than that of normal people. This kind of substance that can cause strong constriction and spasm of local blood vessels, resulting in reduced blood supply to the head, can cause hair to dry up, fall off or turn white. Hair blood flow detection also confirmed that the hair loss patient's scalp not only has organizational and medical changes, but also has abnormal phenomena such as high blood flow resistance, low blood flow total amount, and reduced effective perfusion.

从营养学理论来看,脱发白发的主要原因有二:一是是主食和水果蔬菜摄入不足导致气血亏虚、肾气不足。历代养生家一直提倡健康的饮食需要“五谷为充,五果为养”。即人体每天必须摄入一定量的主食和水果蔬菜,然而,最近的一份调查表明,现代城市人的主食消费量越来越少,已有不足之势,容易导致气血亏虚,肾气不足;二是肉食摄入过多,因营养不均衡而使肾气受损,容易引起脂溢性脱发和白发。以上可以看出,中医和营养学的理论阐述的脱发原因是一致的。From the perspective of nutrition theory, there are two main reasons for hair loss and gray hair: one is insufficient intake of staple food, fruits and vegetables, which leads to deficiency of qi and blood and deficiency of kidney qi. Health preservers of all ages have always advocated that a healthy diet requires "five grains for filling and five fruits for nourishment". That is, the human body must consume a certain amount of staple food, fruits and vegetables every day. However, a recent survey shows that the staple food consumption of modern urban people is getting less and less. Insufficient; the second is excessive intake of meat, which will damage the kidney qi due to unbalanced nutrition, which will easily cause seborrheic alopecia and gray hair. It can be seen from the above that the causes of hair loss explained by the theories of traditional Chinese medicine and nutrition are consistent.

目前,市场上用于防治脱发和白发的药物很多,但多存在起效慢、疗程长、容易复发、效果有限等不足之处,且大部分只对病理性脱发有一定疗效,功能比较单一,极少有兼备防脱和乌发功能的产品。此外,由于白发治疗产品效果有限,大多数人采用化学染发剂来掩盖白发现象,而化学染发剂中的对苯二胺为致癌物质,有很强烈的致敏作用,接触头皮会通过毛囊进入人体内,导致皮肤过敏、接触性皮炎湿疹、白血病、支气管哮喘等病状。At present, there are many drugs on the market for the prevention and treatment of hair loss and gray hair, but most of them have shortcomings such as slow onset of effect, long course of treatment, easy recurrence, and limited effect, and most of them only have certain curative effect on pathological alopecia, and their functions are relatively single , there are very few products that have both anti-hair loss and black hair functions. In addition, due to the limited effect of gray hair treatment products, most people use chemical hair dyes to cover up gray hair, and p-phenylenediamine in chemical hair dyes is a carcinogen and has a strong sensitizing effect. Enter the human body, causing skin allergies, contact dermatitis eczema, leukemia, bronchial asthma and other symptoms.

由此可见,能否发明出一种高效治疗脱发并具有乌发功能的中药组合物,成为本领域技术人员接待解决的技术难题。This shows, whether can invent a kind of Chinese medicine composition that effectively treats alopecia and has black hair function, becomes the technical problem that those skilled in the art welcome to solve.

发明内容Contents of the invention

本发明为了解决上述技术问题,根据中医理论和营养均衡原理,经过多年实践研究,发明出一种标本兼治、效果好,见效快,成本低,使用方便、无毒副作用的内服外用中药组合物,同时具备防治脱发和白发转黑功效。In order to solve the above-mentioned technical problems, the present invention, according to the theory of traditional Chinese medicine and the principle of balanced nutrition, has invented a traditional Chinese medicine composition for internal and external use with good effect, quick effect, low cost, easy to use, and no toxic and side effects after many years of practical research. At the same time, it has the effect of preventing hair loss and turning white hair to black.

为了达到上述技术效果,本发明的技术方案包括:In order to achieve the above-mentioned technical effect, technical scheme of the present invention comprises:

一种治疗脱发并具有乌发功能的中药组合物,所述的中药组合物包括内服制剂中药组合物和外用中药组合物,所述内服制剂中药组合物的原料包括以下重量份数的组分:松针10~30份,旱莲草10~30份,桑椹10~30份,蒲公英10~20份,黑芝麻20~40份,紫草10~20份,丹参5~15份,桑叶10~20份,决明子20~30份,白花蛇舌草15~25份、补骨脂10~30份,黄芪10~25份,葛根10~25份,女贞子10~20份,熟地10~25份,何首乌20~40份,苦参10~20份,红花8~15份,浙贝母10~20份,侧柏叶15~25份,甘草10~15份,当归10~30份,大黄15~25份,黑豆20~40份,虎杖20~30份;所述外用中药组合物的原料包括以下重量份数的组分:何首乌50~80份,黑豆30~60份、黑芝麻20~40份,黄芪10~30份,灵芝10~20份、桑椹20~30份,旱莲草15~30份,补骨脂10~30份,侧柏叶15~35份,松针20~40份,皂角10~20份、生地20~30份,薄荷10~15份,蒺藜20~30份。A traditional Chinese medicine composition for treating hair loss and having the function of blackening hair. The traditional Chinese medicine composition includes a traditional Chinese medicine composition for internal use and a traditional Chinese medicine composition for external use. The raw materials of the traditional Chinese medicine composition for internal use include the following components in parts by weight: 10-30 parts of pine needles, 10-30 parts of ecliptas, 10-30 parts of mulberry, 10-20 parts of dandelion, 20-40 parts of black sesame, 10-20 parts of comfrey, 5-15 parts of salvia miltiorrhiza, 10-20 parts of mulberry leaves 20 parts, 20-30 parts of cassia seed, 15-25 parts of Hedyotis diffusa, 10-30 parts of psoralen, 10-25 parts of astragalus, 10-25 parts of kudzu root, 10-20 parts of Ligustrum lucidum, 10-25 parts of Rehmannia glutinosa 20-40 parts of Polygonum multiflorum, 10-20 parts of Sophora flavescens, 8-15 parts of safflower, 10-20 parts of Fritillaria arborvitae, 15-25 parts of arborvitae leaves, 10-15 parts of licorice, 10-30 parts of angelica, 15-25 parts of rhubarb, 20-40 parts of black beans, 20-30 parts of Polygonum cuspidatum; the raw materials of the traditional Chinese medicine composition for external use include the following components in parts by weight: 50-80 parts of Polygonum multiflorum, 30-60 parts of black beans, 20 parts of black sesame ~40 parts, Astragalus 10~30 parts, Ganoderma lucidum 10~20 parts, Mulberry 20~30 parts, Eclipta 15~30 parts, Psoralen 10~30 parts, Arborvitae leaves 15~35 parts, pine needles 20~40 parts 10 to 20 parts of saponins, 20 to 30 parts of raw land, 10 to 15 parts of mint, and 20 to 30 parts of tribulus.

优选地,所述内服制剂中药组合物的原料包括以下重量份数的组分:松针20份,旱莲草20份,桑椹20份,蒲公英15份,黑芝麻30份,紫草15份,丹参10份,桑叶12份,决明子25份,白花蛇舌草20份、补骨脂20份,黄芪15份,葛根15份,女贞子15份,熟地15份,何首乌30份,苦参15份,红花12份,浙贝母15份,侧柏叶20份,甘草12份,当归20份,大黄20份,黑豆30份,虎杖25份;所述外用中药组合物的原料包括以下重量份数的组分:何首乌65份,黑豆45份、黑芝麻30份,黄芪20份,灵芝15份、桑椹25份,旱莲草25份,补骨脂20份,侧柏叶22份,松针30份,皂角15份、生地25份,薄荷12份,蒺藜25份。Preferably, the raw materials of the traditional Chinese medicine composition for internal administration include the following components in parts by weight: 20 parts of pine needles, 20 parts of Eclipta, 20 parts of mulberry, 15 parts of dandelion, 30 parts of black sesame, 15 parts of comfrey, and Danshen 10 parts, 12 parts of mulberry leaves, 25 parts of cassia seed, 20 parts of Hedyotis diffusa, 20 parts of psoralen, 15 parts of astragalus, 15 parts of kudzu root, 15 parts of Ligustrum lucidum, 15 parts of Rehmannia glutinosa, 30 parts of Polygonum multiflorum, 15 parts of Sophora flavescens 12 parts, 12 parts of safflower, 15 parts of Fritillaria arborvitae, 20 parts of orientalis leaves, 12 parts of licorice, 20 parts of angelica, 20 parts of rhubarb, 30 parts of black beans, 25 parts of Polygonum cuspidatum; the raw materials of the external Chinese medicine composition include the following weight The number of components: 65 parts of Polygonum multiflorum, 45 parts of black beans, 30 parts of black sesame, 20 parts of Astragalus, 15 parts of Ganoderma lucidum, 25 parts of mulberry, 25 parts of Eclipta, 20 parts of psoralen, 22 parts of arborvitae leaves, pine needles 30 parts, saponins 15 parts, raw land 25 parts, mint 12 parts, and tribulus terrestris 25 parts.

所述外用中药组合物还包括溶剂和铜盐。The external Chinese medicine composition also includes solvent and copper salt.

所述溶剂为乙醇和水。The solvent is ethanol and water.

所述外用中药组合物中铜盐的浓度为0.02~0.06g/L。The concentration of the copper salt in the traditional Chinese medicine composition for external use is 0.02-0.06 g/L.

一种治疗脱发并具有乌发功能的中药组合物的制备方法,包括以下步骤:A preparation method of a traditional Chinese medicine composition for treating hair loss and having the function of blackening hair, comprising the following steps:

步骤一:制备内服制剂中药组合物:称取以下重量份数的原料组分:松针10~30份,旱莲草10~30份,桑椹10~30份,蒲公英10~20份,黑芝麻20~40份,紫草10~20份,丹参5~15份,桑叶10~20份,决明子20~30份,白花蛇舌草15~25份、补骨脂10~30份,黄芪10~25份,葛根10~25份,女贞子10~20份,熟地10~25份,何首乌20~40份,苦参10~20份,红花8~15份,浙贝母10~20份,侧柏叶15~25份,甘草10~15份,当归10~30份,大黄15~25份,黑豆20~40份,虎杖20~30份,将各组分干燥,粉碎过10~30目筛,得粗粉,将得到的所述粗粉混合均匀、干热灭菌,装袋,规格为8~10g/袋;Step 1: Preparation of oral preparation Chinese medicine composition: Weigh the following raw material components in parts by weight: 10-30 parts of pine needles, 10-30 parts of Eclipta, 10-30 parts of mulberry, 10-20 parts of dandelion, and 20 parts of black sesame ~40 parts, 10~20 parts of comfrey, 5~15 parts of salvia miltiorrhiza, 10~20 parts of mulberry leaves, 20~30 parts of cassia seed, 15~25 parts of Hedyotis diffusa, 10~30 parts of psoralen, 10~20 parts of astragalus 25 parts, Pueraria 10-25 parts, Ligustrum lucidum 10-20 parts, Rehmannia glutinosa 10-25 parts, Polygonum multiflorum 20-40 parts, Sophora flavescens 10-20 parts, Safflower 8-15 parts, Fritillaria 10-20 parts , 15-25 parts of arborvitae leaves, 10-15 parts of licorice, 10-30 parts of angelica, 15-25 parts of rhubarb, 20-40 parts of black soybeans, 20-30 parts of knotweed, dry each component, crush 10-30 parts Mesh sieve to obtain coarse powder, the obtained coarse powder is mixed evenly, dry heat sterilized, bagged, the specification is 8~10g/bag;

步骤二:制备外用中药组合物:称取以下重量份数的原料组分:何首乌50~80份,黑豆30~60份、黑芝麻20~40份,黄芪10~30份,灵芝10~20份、桑椹20~30份,旱莲草15~30份,补骨脂10~30份,侧柏叶15~35份,松针20~40份,皂角10~20份、生地20~30份,薄荷10~15份,蒺藜20~30份,将上述各组分混合后粉碎成粗粉,按照所述粗粉和乙醇1:8(W/V)比例加入质量分数为50~75%的乙醇,浸泡7天后,过滤,分别留下滤液和药渣;将所述药渣中加入蒸馏水浸泡12~24小时后,所述药渣与所述蒸馏水的体积比为1:2~1:4,温火加热15分钟,冷却至室温,过滤,得滤液;将两次得到的滤液混合成溶液,调整所述溶液总体积为所述粗粉体积的5倍,并使乙醇占所述溶液的质量百分比为10~20%,再向上述滤液中加入铜盐,使所述外用中药组合物中铜盐的浓度为0.02~0.06g/L。Step 2: Preparation of a traditional Chinese medicine composition for external use: weighing the following raw material components in parts by weight: 50-80 parts of Polygonum multiflorum, 30-60 parts of black beans, 20-40 parts of black sesame, 10-30 parts of Radix Astragali, and 10-20 parts of Ganoderma lucidum , 20-30 parts of mulberry, 15-30 parts of eclipta, 10-30 parts of psoralen, 15-35 parts of arborvitae leaves, 20-40 parts of pine needles, 10-20 parts of saponins, 20-30 parts of raw land, 10-15 parts of peppermint, 20-30 parts of Tribulus terrestris, mix the above-mentioned components and grind them into coarse powder, add ethanol with a mass fraction of 50-75% according to the ratio of the coarse powder and ethanol 1:8 (W/V) After soaking for 7 days, filter to leave the filtrate and medicinal residues respectively; after adding distilled water to the medicinal residues and soaking for 12 to 24 hours, the volume ratio of the medicinal residues to the distilled water is 1:2 to 1:4, Heated on warm fire for 15 minutes, cooled to room temperature, filtered to obtain the filtrate; the filtrate obtained twice was mixed into a solution, the total volume of the solution was adjusted to be 5 times the volume of the coarse powder, and ethanol accounted for the mass of the solution The percentage is 10-20%, and copper salt is added to the above filtrate, so that the concentration of copper salt in the external Chinese medicine composition is 0.02-0.06g/L.

一种治疗脱发并具有乌发功能的中药组合物的施药方法,将所述内服制剂中药组合物经沸腾开水冲泡10~15min,每次冲泡8~10g,一天两次,洗发后将所述外用中药组合物均匀涂抹于脱发部位并轻轻按摩5~10分钟至药物完全吸收,每次用药4~7ml,每天1~2次。A method of applying a traditional Chinese medicine composition for treating hair loss and having the function of blackening hair. The traditional Chinese medicine composition of the oral preparation is brewed in boiling water for 10-15 minutes, 8-10 g each time, twice a day, and after shampooing Apply the traditional Chinese medicine composition for external use evenly on the hair loss area and massage gently for 5-10 minutes until the medicine is completely absorbed, 4-7ml each time, 1-2 times a day.

本发明的有益效果包括:本发明根据中医理论和营养均衡原理,经过多年实践研究,精选出各原料药及其配比,并采用内服外用相结合的服药方式,达到治疗脱发并具有乌发功能效果,并且使头发更加乌黑亮泽,效果显著,具有标本兼治、效果好,见效快,成本低,使用方便、无毒副作用的优点。The beneficial effects of the present invention include: according to the theory of traditional Chinese medicine and the principle of nutritional balance, the present invention selects various raw materials and their proportions after years of practical research, and adopts a combination of oral administration and external administration, so as to treat hair loss and have black hair. It has the advantages of treating both symptoms and root causes, good effect, quick effect, low cost, convenient use and no side effects.

具体实施方式Detailed ways

下文将具体详细描述本发明具体实施例。应当注意的是,下述实施例中描述的技术特征或者技术特征的组合不应当被认为是孤立的,它们可以被相互组合从而达到更好的技术效果。Specific embodiments of the present invention will be described in detail below. It should be noted that the technical features or combinations of technical features described in the following embodiments should not be regarded as isolated, and they can be combined with each other to achieve better technical effects.

实施例1Example 1

一种治疗脱发并具有乌发功能的中药组合物,所述的中药组合物包括内服制剂中药组合物和外用中药组合物,所述内服制剂中药组合物的原料包括以下重量份数的组分:松针10份,旱莲草10份,桑椹30份,蒲公英10份,黑芝麻40份,紫草10份,丹参15份,桑叶10份,决明子30份,白花蛇舌草15份、补骨脂30份,黄芪10份,葛根25份,女贞子10份,熟地25份,何首乌20份,苦参20份,红花8份,浙贝母20份,侧柏叶15份,甘草15份,当归10份,大黄25份,黑豆20份,虎杖30份;所述外用中药组合物的原料包括以下重量份数的组分:何首乌50份,黑豆60份、黑芝麻20份,黄芪30份,灵芝10份、桑椹30份,旱莲草15份,补骨脂30份,侧柏叶15份,松针40份,皂角10份、生地30份,薄荷10份,蒺藜30份。A traditional Chinese medicine composition for treating hair loss and having the function of blackening hair. The traditional Chinese medicine composition includes a traditional Chinese medicine composition for internal use and a traditional Chinese medicine composition for external use. The raw materials of the traditional Chinese medicine composition for internal use include the following components in parts by weight: 10 parts of pine needles, 10 parts of eclipta, 30 parts of mulberry, 10 parts of dandelion, 40 parts of black sesame, 10 parts of comfrey, 15 parts of salvia miltiorrhiza, 10 parts of mulberry leaves, 30 parts of cassia seed, 15 parts of Hedyotis diffusa, Bu Gu 30 parts of fat, 10 parts of astragalus, 25 parts of kudzu root, 10 parts of Ligustrum lucidum, 25 parts of Rehmannia glutinosa, 20 parts of Polygonum multiflorum, 20 parts of Sophora flavescens, 8 parts of safflower, 20 parts of Fritillaria, 15 parts of oriental cypress leaves, 15 parts of licorice 10 parts, 10 parts of angelica, 25 parts of rhubarb, 20 parts of black beans, 30 parts of Polygonum cuspidatum; the raw materials of the external Chinese medicine composition include the following components in parts by weight: 50 parts of Polygonum multiflorum, 60 parts of black beans, 20 parts of black sesame, 30 parts of Astragalus 10 parts of Ganoderma lucidum, 30 parts of mulberry, 15 parts of Eclipta, 30 parts of psoralen, 15 parts of arborvitae leaves, 40 parts of pine needles, 10 parts of saponins, 30 parts of raw land, 10 parts of mint, and 30 parts of Tribulus terrestris.

所述外用中药组合物还包括溶剂和铜盐,所述溶剂为乙醇和水。所述外用中药组合物中铜盐的浓度为0.02~0.06g/L。The traditional Chinese medicine composition for external use also includes a solvent and a copper salt, and the solvent is ethanol and water. The concentration of the copper salt in the traditional Chinese medicine composition for external use is 0.02-0.06 g/L.

一种治疗脱发并具有乌发功能的中药组合物的制备方法,所述制备方法,包括以下步骤:A preparation method of a traditional Chinese medicine composition for treating hair loss and having the function of blackening hair, the preparation method comprises the following steps:

步骤一:制备内服制剂中药组合物:称取以下重量份数的原料组分:松针10份,旱莲草10份,桑椹30份,蒲公英10份,黑芝麻40份,紫草10份,丹参15份,桑叶10份,决明子30份,白花蛇舌草15份、补骨脂30份,黄芪10份,葛根25份,女贞子10份,熟地25份,何首乌20份,苦参20份,红花8份,浙贝母20份,侧柏叶15份,甘草15份,当归10份,大黄25份,黑豆20份,虎杖30份,将各组分干燥,粉碎过10~30目筛,得粗粉,将得到的所述粗粉混合均匀、干热灭菌,装袋,规格为8~10g/袋;Step 1: Preparation of oral preparation Chinese medicine composition: Weigh the following raw material components in parts by weight: 10 parts of pine needles, 10 parts of Eclipta, 30 parts of mulberry, 10 parts of dandelion, 40 parts of black sesame, 10 parts of comfrey, and Danshen 15 parts, 10 parts of mulberry leaves, 30 parts of cassia seed, 15 parts of Hedyotis diffusa, 30 parts of psoralen, 10 parts of astragalus, 25 parts of kudzu root, 10 parts of Ligustrum lucidum, 25 parts of Rehmannia glutinosa, 20 parts of Polygonum multiflorum, 20 parts of Sophora flavescens 8 parts of safflower, 20 parts of Fritillaria, 15 parts of orientalis leaves, 15 parts of licorice, 10 parts of angelica, 25 parts of rhubarb, 20 parts of black beans, 30 parts of knotweed, dry each component, crush 10-30 parts Mesh sieve to obtain coarse powder, the obtained coarse powder is mixed evenly, dry heat sterilized, bagged, the specification is 8~10g/bag;

步骤二:制备外用中药组合物:称取以下重量份数的原料组分:何首乌50份,黑豆60份、黑芝麻20份,黄芪30份,灵芝10份、桑椹30份,旱莲草15份,补骨脂30份,侧柏叶15份,松针40份,皂角10份、生地30份,薄荷10份,蒺藜30份,将上述各组分混合后粉碎成粗粉,按照所述粗粉和乙醇1:8(W/V)比例加入质量分数为50~75%的乙醇,浸泡7天后,过滤,分别留下滤液和药渣;将所述药渣中加入蒸馏水浸泡12~24小时后,所述药渣与所述蒸馏水的体积比为1:2~1:4,温火加热15分钟,冷却至室温,过滤,得滤液;将两次得到的滤液混合成溶液,调整所述溶液总体积为所述粗粉体积的5倍,并使乙醇占所述溶液的质量百分比为10~20%,再向上述滤液中加入铜盐,使所述外用中药组合物中铜盐的浓度为0.02~0.06g/L。Step 2: Preparation of a traditional Chinese medicine composition for external use: Weigh the following raw material components in parts by weight: 50 parts of Polygonum multiflorum, 60 parts of black beans, 20 parts of black sesame, 30 parts of Astragalus membranaceus, 10 parts of Ganoderma lucidum, 30 parts of mulberries, and 15 parts of Eclipta , 30 parts of psoralen, 15 parts of arborvitae leaves, 40 parts of pine needles, 10 parts of saponins, 30 parts of raw land, 10 parts of mint, 30 parts of tribulus, mix the above-mentioned components and grind them into coarse powder. powder and ethanol at a ratio of 1:8 (W/V), add ethanol with a mass fraction of 50-75%, soak for 7 days, filter, and leave the filtrate and medicinal residues respectively; add distilled water to the medicinal residues and soak for 12-24 hours Finally, the volume ratio of the medicinal residues to the distilled water is 1:2 to 1:4, heated with warm fire for 15 minutes, cooled to room temperature, and filtered to obtain the filtrate; the filtrate obtained twice was mixed into a solution, and the The total volume of the solution is 5 times the volume of the coarse powder, and the mass percentage of ethanol in the solution is 10-20%, and then copper salt is added to the above filtrate to make the concentration of the copper salt in the external Chinese medicine composition It is 0.02~0.06g/L.

一种治疗脱发并具有乌发功能的中药组合物的施药方法,将所述内服制剂中药组合物经沸腾开水冲泡10~15min,每次冲泡8~10g,一天两次,洗发后将所述外用中药组合物均匀涂抹于脱发部位并轻轻按摩5~10分钟至药物完全吸收,每次用药4~7ml,每天1~2次。以上内服外用药同时服用,7天可以控制头皮出油和瘙痒,10天脱发现象明显减少,30天为一疗程,生发一般1~3个疗程,白发转黑3~6个疗程。A method of applying a traditional Chinese medicine composition for treating hair loss and having the function of blackening hair. The traditional Chinese medicine composition of the oral preparation is brewed in boiling water for 10-15 minutes, 8-10 g each time, twice a day, and after shampooing Apply the traditional Chinese medicine composition for external use evenly on the hair loss area and massage gently for 5-10 minutes until the medicine is completely absorbed, 4-7ml each time, 1-2 times a day. Take the above internal and external medicines at the same time, 7 days can control scalp oil and itching, 10 days hair loss phenomenon is significantly reduced, 30 days is a course of treatment, hair growth generally takes 1 to 3 courses, and white hair turns black 3 to 6 courses of treatment.

实施例2Example 2

一种治疗脱发并具有乌发功能的中药组合物,所述的中药组合物包括内服制剂中药组合物和外用中药组合物,所述内服制剂中药组合物的原料包括以下重量份数的组分:松针20份,旱莲草20份,桑椹20份,蒲公英15份,黑芝麻30份,紫草15份,丹参10份,桑叶12份,决明子25份,白花蛇舌草20份、补骨脂20份,黄芪15份,葛根15份,女贞子15份,熟地15份,何首乌30份,苦参15份,红花12份,浙贝母15份,侧柏叶20份,甘草12份,当归20份,大黄20份,黑豆30份,虎杖25份;所述外用中药组合物的原料包括以下重量份数的组分:何首乌65份,黑豆45份、黑芝麻30份,黄芪20份,灵芝15份、桑椹25份,旱莲草25份,补骨脂20份,侧柏叶22份,松针30份,皂角15份、生地25份,薄荷12份,蒺藜25份。A traditional Chinese medicine composition for treating hair loss and having the function of blackening hair. The traditional Chinese medicine composition includes a traditional Chinese medicine composition for internal use and a traditional Chinese medicine composition for external use. The raw materials of the traditional Chinese medicine composition for internal use include the following components in parts by weight: 20 parts of pine needles, 20 parts of eclipta, 20 parts of mulberry, 15 parts of dandelion, 30 parts of black sesame, 15 parts of comfrey, 10 parts of salvia miltiorrhiza, 12 parts of mulberry leaves, 25 parts of cassia seed, 20 parts of Hedyotis diffusa, Bu Gu 20 parts of fat, 15 parts of astragalus, 15 parts of kudzu root, 15 parts of Ligustrum lucidum, 15 parts of Rehmannia glutinosa, 30 parts of Polygonum multiflorum, 15 parts of Sophora flavescens, 12 parts of safflower, 15 parts of Fritillaria, 20 parts of oriental cypress leaves, 12 parts of licorice 20 parts, 20 parts of angelica, 20 parts of rhubarb, 30 parts of black soybeans, 25 parts of Polygonum cuspidatum; the raw materials of the external Chinese medicine composition include the following components in parts by weight: 65 parts of Polygonum multiflorum, 45 parts of black soybeans, 30 parts of black sesame, 20 parts of Radix Astragali 15 parts of ganoderma lucidum, 25 parts of mulberry, 25 parts of eclipta, 20 parts of psoralen, 22 parts of arborvitae leaves, 30 parts of pine needles, 15 parts of saponins, 25 parts of raw land, 12 parts of mint, and 25 parts of tribulus terrestris.

所述外用中药组合物还包括溶剂和铜盐,所述溶剂为乙醇和水。所述外用中药组合物中铜盐的浓度为0.02~0.06g/L。The traditional Chinese medicine composition for external use also includes a solvent and a copper salt, and the solvent is ethanol and water. The concentration of the copper salt in the traditional Chinese medicine composition for external use is 0.02-0.06 g/L.

一种治疗脱发并具有乌发功能的中药组合物的制备方法,所述制备方法,包括以下步骤:A preparation method of a traditional Chinese medicine composition for treating hair loss and having the function of blackening hair, the preparation method comprises the following steps:

步骤一:制备内服制剂中药组合物:称取以下重量份数的原料组分:松针20份,旱莲草20份,桑椹20份,蒲公英15份,黑芝麻30份,紫草15份,丹参10份,桑叶12份,决明子25份,白花蛇舌草20份、补骨脂20份,黄芪15份,葛根15份,女贞子15份,熟地15份,何首乌30份,苦参15份,红花12份,浙贝母15份,侧柏叶20份,甘草12份,当归20份,大黄20份,黑豆30份,虎杖25份,将各组分干燥,粉碎过10~30目筛,得粗粉,将得到的所述粗粉混合均匀、干热灭菌,装袋,规格为8~10g/袋;Step 1: Preparation of oral preparation Chinese medicine composition: Weigh the following raw material components in parts by weight: 20 parts of pine needles, 20 parts of Eclipta, 20 parts of mulberry, 15 parts of dandelion, 30 parts of black sesame, 15 parts of comfrey, and salvia miltiorrhiza 10 parts, 12 parts of mulberry leaves, 25 parts of cassia seed, 20 parts of Hedyotis diffusa, 20 parts of psoralen, 15 parts of astragalus, 15 parts of kudzu root, 15 parts of Ligustrum lucidum, 15 parts of Rehmannia glutinosa, 30 parts of Polygonum multiflorum, 15 parts of Sophora flavescens 12 parts of safflower, 15 parts of Fritillaria arborvitae, 20 parts of cypress leaves, 12 parts of licorice, 20 parts of angelica, 20 parts of rhubarb, 30 parts of black beans, 25 parts of knotweed, each component is dried and crushed for 10 to 30 parts. Mesh sieve to obtain coarse powder, the obtained coarse powder is mixed evenly, dry heat sterilized, bagged, the specification is 8~10g/bag;

步骤二:制备外用中药组合物:称取以下重量份数的原料组分::何首乌65份,黑豆45份、黑芝麻30份,黄芪20份,灵芝15份、桑椹25份,旱莲草25份,补骨脂20份,侧柏叶22份,松针30份,皂角15份、生地25份,薄荷12份,蒺藜25份,将上述各组分混合后粉碎成粗粉,按照所述粗粉和乙醇1:8(W/V)比例加入质量分数为50~75%的乙醇,浸泡7天后,过滤,分别留下滤液和药渣;将所述药渣中加入蒸馏水浸泡12~24小时后,所述药渣与所述蒸馏水的体积比为1:2~1:4,温火加热15分钟,冷却至室温,过滤,得滤液;将两次得到的滤液混合成溶液,调整所述溶液总体积为所述粗粉体积的5倍,并使乙醇占所述溶液的质量百分比为10~20%,再向上述滤液中加入铜盐,使所述外用中药组合物中铜盐的浓度为0.02~0.06g/L。Step 2: Preparation of external Chinese medicine composition: Weigh the following raw material components in parts by weight: 65 parts of Polygonum multiflorum, 45 parts of black beans, 30 parts of black sesame, 20 parts of Astragalus, 15 parts of Ganoderma lucidum, 25 parts of mulberry, 25 parts of Eclipta 20 parts of psoraleae, 22 parts of orientalis leaves, 30 parts of pine needles, 15 parts of saponins, 25 parts of raw land, 12 parts of mint, and 25 parts of tribulus. Mix the above components and grind them into coarse powder. Coarse powder and ethanol 1:8 (W/V) ratio add the ethanol that mass fraction is 50~75%, after soaking for 7 days, filter, leave filtrate and dregs respectively; Add distilled water to the dregs and soak for 12~24 Hours later, the volume ratio of the medicinal residues to the distilled water was 1:2 to 1:4, heated with warm fire for 15 minutes, cooled to room temperature, and filtered to obtain the filtrate; the filtrate obtained twice was mixed into a solution, and adjusted The total volume of the solution is 5 times the volume of the coarse powder, and the mass percentage of ethanol in the solution is 10-20%, and then copper salt is added to the above-mentioned filtrate to make the content of the copper salt in the external Chinese medicine composition The concentration is 0.02~0.06g/L.

一种治疗脱发并具有乌发功能的中药组合物的施药方法,将所述内服制剂中药组合物经沸腾开水冲泡10~15min,每次冲泡8~10g,一天两次,洗发后将所述外用中药组合物均匀涂抹于脱发部位并轻轻按摩5~10分钟至药物完全吸收,每次用药4~7ml,每天1~2次。以上内服外用药同时服用,7天可以控制头皮出油和瘙痒,10天脱发现象明显减少,30天为一疗程,生发一般1~3个疗程,白发转黑3~6个疗程。A method of applying a traditional Chinese medicine composition for treating hair loss and having the function of blackening hair. The traditional Chinese medicine composition of the oral preparation is brewed in boiling water for 10-15 minutes, 8-10 g each time, twice a day, and after shampooing Apply the traditional Chinese medicine composition for external use evenly on the hair loss area and massage gently for 5-10 minutes until the medicine is completely absorbed, 4-7ml each time, 1-2 times a day. Take the above internal and external medicines at the same time, 7 days can control scalp oil and itching, 10 days hair loss phenomenon is significantly reduced, 30 days is a course of treatment, hair growth generally takes 1 to 3 courses, and white hair turns black 3 to 6 courses of treatment.

实施例3Example 3

一种治疗脱发并具有乌发功能的中药组合物,所述的中药组合物包括内服制剂中药组合物和外用中药组合物,所述内服制剂中药组合物的原料包括以下重量份数的组分:松针30份,旱莲草30份,桑椹10份,蒲公英20份,黑芝麻20份,紫草20份,丹参5份,桑叶20份,决明子20份,白花蛇舌草25份、补骨脂10份,黄芪25份,葛根10份,女贞子20份,熟地10份,何首乌40份,苦参30份,红花15份,浙贝母10份,侧柏叶25份,甘草10份,当归30份,大黄15份,黑豆40份,虎杖20份;所述外用中药组合物的原料包括以下重量份数的组分:何首乌80份,黑豆30份、黑芝麻40份,黄芪10份,灵芝20份、桑椹20份,旱莲草30份,补骨脂10份,侧柏叶35份,松针20份,皂角20份、生地20份,薄荷15份,蒺藜20份。A traditional Chinese medicine composition for treating hair loss and having the function of blackening hair. The traditional Chinese medicine composition includes a traditional Chinese medicine composition for internal use and a traditional Chinese medicine composition for external use. The raw materials of the traditional Chinese medicine composition for internal use include the following components in parts by weight: 30 parts of pine needles, 30 parts of eclipta, 10 parts of mulberry, 20 parts of dandelion, 20 parts of black sesame, 20 parts of comfrey, 5 parts of salvia miltiorrhiza, 20 parts of mulberry leaves, 20 parts of cassia seed, 25 parts of Hedyotis diffusa, Bu Gu 10 parts of fat, 25 parts of astragalus, 10 parts of kudzu root, 20 parts of Ligustrum lucidum, 10 parts of Rehmannia glutinosa, 40 parts of Polygonum multiflorum, 30 parts of Sophora flavescens, 15 parts of safflower, 10 parts of Fritillaria, 25 parts of oriental cypress leaves, 10 parts of licorice 30 parts of Chinese angelica, 15 parts of rhubarb, 40 parts of black beans, 20 parts of Polygonum cuspidatum; the raw materials of the external Chinese medicine composition include the following components in parts by weight: 80 parts of Polygonum multiflorum, 30 parts of black beans, 40 parts of black sesame, 10 parts of Radix Astragali 20 parts of ganoderma lucidum, 20 parts of mulberry, 30 parts of eclipta, 10 parts of psoralen, 35 parts of arborvitae leaves, 20 parts of pine needles, 20 parts of saponins, 20 parts of raw land, 15 parts of mint, and 20 parts of tribulus terrestris.

所述外用中药组合物还包括溶剂和铜盐,所述溶剂为乙醇和水。所述外用中药组合物中铜盐的浓度为0.02~0.06g/L。The traditional Chinese medicine composition for external use also includes a solvent and a copper salt, and the solvent is ethanol and water. The concentration of the copper salt in the traditional Chinese medicine composition for external use is 0.02-0.06 g/L.

一种治疗脱发并具有乌发功能的中药组合物的制备方法,所述制备方法,包括以下步骤:A preparation method of a traditional Chinese medicine composition for treating hair loss and having the function of blackening hair, the preparation method comprises the following steps:

步骤一:制备内服制剂中药组合物:称取以下重量份数的原料组分:松针30份,旱莲草30份,桑椹10份,蒲公英20份,黑芝麻20份,紫草20份,丹参5份,桑叶20份,决明子20份,白花蛇舌草25份、补骨脂10份,黄芪25份,葛根10份,女贞子20份,熟地10份,何首乌40份,苦参30份,红花15份,浙贝母10份,侧柏叶25份,甘草10份,当归30份,大黄15份,黑豆40份,虎杖20份,将各组分干燥,粉碎过10~30目筛,得粗粉,将得到的所述粗粉混合均匀、干热灭菌,装袋,规格为8~10g/袋;Step 1: Preparation of Chinese medicine composition for internal administration: Weigh the following raw material components in parts by weight: 30 parts of pine needles, 30 parts of Eclipta, 10 parts of mulberry, 20 parts of dandelion, 20 parts of black sesame, 20 parts of comfrey, and salvia miltiorrhiza 5 parts, 20 parts of mulberry leaves, 20 parts of cassia seed, 25 parts of Hedyotis diffusa, 10 parts of psoralen, 25 parts of astragalus, 10 parts of kudzu root, 20 parts of Ligustrum lucidum, 10 parts of Rehmannia glutinosa, 40 parts of Polygonum multiflorum, 30 parts of Sophora flavescens 15 parts of safflower, 10 parts of Fritillaria arborvitae, 25 parts of orientalis leaves, 10 parts of licorice, 30 parts of angelica, 15 parts of rhubarb, 40 parts of black beans, 20 parts of knotweed, each component was dried and crushed for 10-30 Mesh sieve to obtain coarse powder, the obtained coarse powder is mixed evenly, dry heat sterilized, bagged, the specification is 8~10g/bag;

步骤二:制备外用中药组合物:称取以下重量份数的原料组分:何首乌80份,黑豆30份、黑芝麻40份,黄芪10份,灵芝20份、桑椹20份,旱莲草30份,补骨脂10份,侧柏叶35份,松针20份,皂角20份、生地20份,薄荷15份,蒺藜20份,将上述各组分混合后粉碎成粗粉,按照所述粗粉和乙醇1:8(W/V)比例加入质量分数为50~75%的乙醇,浸泡7天后,过滤,分别留下滤液和药渣;将所述药渣中加入蒸馏水浸泡12~24小时后,所述药渣与所述蒸馏水的体积比为1:2~1:4,温火加热15分钟,冷却至室温,过滤,得滤液;将两次得到的滤液混合成溶液,调整所述溶液总体积为所述粗粉体积的5倍,并使乙醇占所述溶液的质量百分比为10~20%,再向上述滤液中加入铜盐,使所述外用中药组合物中铜盐的浓度为0.02~0.06g/L。Step 2: Preparation of a traditional Chinese medicine composition for external use: Weigh the following raw material components in parts by weight: 80 parts of Polygonum multiflorum, 30 parts of black beans, 40 parts of black sesame, 10 parts of Astragalus membranaceus, 20 parts of Ganoderma lucidum, 20 parts of mulberries, and 30 parts of Eclipta , 10 parts of psoralen, 35 parts of arborvitae leaves, 20 parts of pine needles, 20 parts of saponins, 20 parts of raw land, 15 parts of peppermint, and 20 parts of tribulus. The above-mentioned components are mixed and crushed into coarse powder. powder and ethanol at a ratio of 1:8 (W/V), add ethanol with a mass fraction of 50-75%, soak for 7 days, filter, and leave the filtrate and medicinal residues respectively; add distilled water to the medicinal residues and soak for 12-24 hours Finally, the volume ratio of the medicinal residues to the distilled water is 1:2 to 1:4, heated with warm fire for 15 minutes, cooled to room temperature, and filtered to obtain the filtrate; the filtrate obtained twice was mixed into a solution, and the The total volume of the solution is 5 times the volume of the coarse powder, and the mass percentage of ethanol in the solution is 10-20%, and then copper salt is added to the above filtrate to make the concentration of the copper salt in the external Chinese medicine composition It is 0.02~0.06g/L.

一种治疗脱发并具有乌发功能的中药组合物的施药方法,将所述内服制剂中药组合物经沸腾开水冲泡10~15min,每次冲泡8~10g,一天两次,洗发后将所述外用中药组合物均匀涂抹于脱发部位并轻轻按摩5~10分钟至药物完全吸收,每次用药4~7ml,每天1~2次。以上内服外用药同时服用,7天可以控制头皮出油和瘙痒,10天脱发现象明显减少,30天为一疗程,生发一般1~3个疗程,白发转黑3~6个疗程。A method of applying a traditional Chinese medicine composition for treating hair loss and having the function of blackening hair. The traditional Chinese medicine composition of the oral preparation is brewed in boiling water for 10-15 minutes, 8-10 g each time, twice a day, and after shampooing Apply the traditional Chinese medicine composition for external use evenly on the hair loss area and massage gently for 5-10 minutes until the medicine is completely absorbed, 4-7ml each time, 1-2 times a day. Take the above internal and external medicines at the same time, 7 days can control scalp oil and itching, 10 days hair loss phenomenon is significantly reduced, 30 days is a course of treatment, hair growth generally takes 1 to 3 courses, and white hair turns black 3 to 6 courses of treatment.

实施例4本发明的中药组合物药效临床实验Embodiment 4 Chinese medicine composition efficacy clinical experiment of the present invention

典型临床实验效果报告描述如下:A typical clinical trial effect report is described as follows:

临床资料:本发明共治疗脱发并伴有大量白发患者60例,并伴有白发,男32例,女28例,年龄为20~50岁。Clinical data: The present invention treats a total of 60 patients with alopecia and a large number of gray hairs, including 32 males and 28 females, aged 20 to 50 years.

治疗方法:本发明的中药组合物分为内服制剂和外用制剂,内服制剂中药组合物经沸腾开水冲泡10~15min,每次冲泡8~10g,一天两次,洗发后将外用中药组合物均匀涂抹于脱发部位并轻轻按摩5~10分钟至药物完全吸收,每次用药4~7ml,每天1~2次。Treatment method: the traditional Chinese medicine composition of the present invention is divided into internal preparation and external preparation. The traditional Chinese medicine composition of the internal preparation is brewed with boiling water for 10 to 15 minutes, 8 to 10 g each time, twice a day, and the external Chinese medicine is combined after shampooing. The drug is evenly applied to the hair loss area and gently massaged for 5-10 minutes until the drug is completely absorbed, 4-7ml each time, 1-2 times a day.

疗效评价标准:Efficacy evaluation criteria:

治愈:脱发区头发生长率达到80%以上,及白发存在数量低于10%。Cure: The hair growth rate in the hair loss area reaches more than 80%, and the number of white hairs is less than 10%.

好转:脱发区头发生长率达到20~80%,及白发存在数量为10~60%。Improvement: the hair growth rate in the hair loss area reaches 20-80%, and the number of white hairs is 10-60%.

未愈:脱发区头发生长率达到低于20%,及白发存在数量高于60%。Unhealed: the hair growth rate in the alopecia area is less than 20%, and the number of white hairs is higher than 60%.

治疗效果:本发明共治疗脱发并伴有大量白发患者60例,经过1~3个疗程,脱发区头发生发率均达到80%以上的有52例,占86.67%,脱发区头发生长率达到20~80%有7例,占11.67%,脱发区头发生长率达到低于20%的仅有1例,未见任何副作用,当经过3~6个疗程,再次统计,患者的白发转黑明显,治愈54例,好转5例,未愈仅有1例,治疗中为见任何副作用,治愈后半年到一年进行随访,均未见复发,结果表明,本发明治疗效果稳定,无副作用,治疗脱发的同时,可明显减少白发。Therapeutic effect: the present invention treats 60 cases of patients with alopecia and a large number of white hairs. After 1-3 courses of treatment, 52 cases have hair growth rates of more than 80% in the alopecia area, accounting for 86.67%. The hair growth rate in the alopecia area reaches 20-80% in 7 cases, accounting for 11.67%. Only 1 case had hair growth rate lower than 20% in the hair loss area, and no side effects were seen. After 3-6 courses of treatment, the patient's white hair turned black again Obviously, 54 cases were cured, 5 cases took a turn for the better, and only 1 case was not cured. During the treatment, no side effects were seen. Follow-up was carried out from half a year to one year after the cure, and no recurrence was found. The results show that the present invention has a stable therapeutic effect and no side effects. While treating hair loss, gray hair can be significantly reduced.

典型病例:Typical cases:

1、李某,女,28岁,工作上压力较大,经常性熬夜,导致脱发严重白发增多,使用本发明的中药组合物4个月后,已治愈,白发几乎看不见,发色恢复黑色亮泽,浓密发多。1. Li, female, 28 years old, has a lot of pressure at work and often stays up late, resulting in severe hair loss and increased white hair. After using the traditional Chinese medicine composition of the present invention for 4 months, it has been cured. The white hair is almost invisible and the hair color Restore black luster, thicker hair.

2、王某,男,35岁,平时生活精神紧张,脱发严重,白发较多,使用本发明的中药组合物5个月后,已治愈,白发几乎看不见,发色恢复黑色亮泽,浓密发多。2. Wang, man, 35 years old, living with stress, severe hair loss, and more gray hairs. After using the traditional Chinese medicine composition of the present invention for 5 months, he has been cured, the gray hairs are almost invisible, and the hair color returns to black luster , thick and hairy.

3、张某,男,45岁,脱发症状持续多年,头发稀少,呈现秃头状态,异常忧虑,使用本发明的中药组合物3个月后,已无脱发现象,并且开始长出新头发,白发减少,继续使用至6个月后,形象大为改观,已治愈,浓密发多,且黑色有亮泽。3, Zhang, man, 45 years old, alopecia symptom persists for many years, hair is rare, presents baldness state, abnormal worry, after using the Chinese medicine composition of the present invention for 3 months, there is no alopecia phenomenon, and begins to grow new hair, white After continuing to use for 6 months, the image has been greatly improved, the hair has been cured, the hair is thicker, and the black is shiny.

上述详细说明是针对发明的可行实施例的具体说明,该实施例并非用以限制本发明的专利范围,凡未脱离本发明的等效实施或变更,均应当包含于本发明的专利范围内。The above detailed description is a specific description of a feasible embodiment of the invention. This embodiment is not intended to limit the patent scope of the present invention. Any equivalent implementation or change that does not deviate from the present invention shall be included in the patent scope of the present invention.

另外,本领域技术人员还可在本发明权利要求公开的范围和精神内做其它形式和细节上的各种修改、添加和替换。当然,这些依据本发明精神所做的各种修改、添加和替换等变化,都应包含在本发明所要求保护的范围之内。In addition, those skilled in the art can also make various modifications, additions and substitutions in other forms and details within the scope and spirit disclosed in the claims of the present invention. Certainly, the various modifications, additions, substitutions and other changes made according to the spirit of the present invention shall all be included within the scope of protection claimed by the present invention.

Claims (7)

1. a hair growth there is the Chinese medicine composition of black hair function, it is characterized in that, described Chinese medicine composition comprises oral preparations Chinese medicine composition and external medicine composition, the raw material of described oral preparations Chinese medicine composition comprises the component of following parts by weight: 10 ~ 30 parts, Folium Pini, Herba Ecliptae 10 ~ 30 parts, 10 ~ 30 parts, Fructus Mori, Herba Taraxaci 10 ~ 20 parts, Semen Sesami Nigrum 20 ~ 40 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 20 parts, Radix Salviae Miltiorrhizae 5 ~ 15 parts, 10 ~ 20 parts, Folium Mori, Semen Cassiae 20 ~ 30 parts, Herba Hedyotidis Diffusae 15 ~ 25 parts, Fructus Psoraleae 10 ~ 30 parts, the Radix Astragali 10 ~ 25 parts, Radix Puerariae 10 ~ 25 parts, Fructus Ligustri Lucidi 10 ~ 20 parts, 10 ~ 25 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 20 ~ 40 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, 8 ~ 15 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 10 ~ 20 parts, Cacumen Platycladi 15 ~ 25 parts, 10 ~ 15 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 10 ~ 30 parts, Radix Et Rhizoma Rhei 15 ~ 25 parts, 20 ~ 40 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 20 ~ 30 parts, the raw material of described external medicine composition comprises the component of following parts by weight: Radix Polygoni Multiflori 50 ~ 80 parts, 30 ~ 60 parts, Semen sojae atricolor, Semen Sesami Nigrum 20 ~ 40 parts, the Radix Astragali 10 ~ 30 parts, Ganoderma 10 ~ 20 parts, 20 ~ 30 parts, Fructus Mori, Herba Ecliptae 15 ~ 30 parts, Fructus Psoraleae 10 ~ 30 parts, Cacumen Platycladi 15 ~ 35 parts, 20 ~ 40 parts, Folium Pini, Fructus Gleditsia 10 ~ 20 parts, 20 ~ 30 parts, the Radix Rehmanniae, Herba Menthae 10 ~ 15 parts, Fructus Tribuli 20 ~ 30 parts.
2. a kind of hair growth according to claim 1 there is the Chinese medicine composition of black hair function, it is characterized in that, the raw material of described oral preparations Chinese medicine composition comprises the component of following parts by weight: 20 parts, Folium Pini, Herba Ecliptae 20 parts, 20 parts, Fructus Mori, Herba Taraxaci 15 parts, Semen Sesami Nigrum 30 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Radix Salviae Miltiorrhizae 10 parts, 12 parts, Folium Mori, Semen Cassiae 25 parts, Herba Hedyotidis Diffusae 20 parts, Fructus Psoraleae 20 parts, the Radix Astragali 15 parts, Radix Puerariae 15 parts, Fructus Ligustri Lucidi 15 parts, 15 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 30 parts, Radix Sophorae Flavescentis 15 parts, 12 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 15 parts, Cacumen Platycladi 20 parts, 12 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 20 parts, Radix Et Rhizoma Rhei 20 parts, 30 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 25 parts, the raw material of described external medicine composition comprises the component of following parts by weight: Radix Polygoni Multiflori 65 parts, 45 parts, Semen sojae atricolor, Semen Sesami Nigrum 30 parts, the Radix Astragali 20 parts, Ganoderma 15 parts, 25 parts, Fructus Mori, Herba Ecliptae 25 parts, Fructus Psoraleae 20 parts, Cacumen Platycladi 22 parts, 30 parts, Folium Pini, Fructus Gleditsia 15 parts, 25 parts, the Radix Rehmanniae, Herba Menthae 12 parts, Fructus Tribuli 25 parts.
3. a kind of hair growth according to any one of claim 1 ~ 2 also has the Chinese medicine composition of black hair function, and it is characterized in that, described external medicine composition also comprises solvent and mantoquita.
4. a kind of hair growth according to claim 3 have the Chinese medicine composition of black hair function, it is characterized in that, described solvent is second alcohol and water.
5. a kind of hair growth according to claim 3 have the Chinese medicine composition of black hair function, it is characterized in that, in described external medicine composition, the concentration of mantoquita is 0.02 ~ 0.06g/L.
6. the hair growth described in any one of Claims 1 to 5 also has the preparation method of the Chinese medicine composition of black hair function, it is characterized in that, comprises the following steps:
Step one: prepare oral preparations Chinese medicine composition: the raw material components taking following parts by weight: 10 ~ 30 parts, Folium Pini, Herba Ecliptae 10 ~ 30 parts, 10 ~ 30 parts, Fructus Mori, Herba Taraxaci 10 ~ 20 parts, Semen Sesami Nigrum 20 ~ 40 parts, Radix Arnebiae (Radix Lithospermi) 10 ~ 20 parts, Radix Salviae Miltiorrhizae 5 ~ 15 parts, 10 ~ 20 parts, Folium Mori, Semen Cassiae 20 ~ 30 parts, Herba Hedyotidis Diffusae 15 ~ 25 parts, Fructus Psoraleae 10 ~ 30 parts, the Radix Astragali 10 ~ 25 parts, Radix Puerariae 10 ~ 25 parts, Fructus Ligustri Lucidi 10 ~ 20 parts, 10 ~ 25 parts, Radix Rehmanniae Preparata, Radix Polygoni Multiflori 20 ~ 40 parts, Radix Sophorae Flavescentis 10 ~ 20 parts, 8 ~ 15 parts, Flos Carthami, Bulbus Fritillariae Thunbergii 10 ~ 20 parts, Cacumen Platycladi 15 ~ 25 parts, 10 ~ 15 parts, Radix Glycyrrhizae, Radix Angelicae Sinensis 10 ~ 30 parts, Radix Et Rhizoma Rhei 15 ~ 25 parts, 20 ~ 40 parts, Semen sojae atricolor, Rhizoma Polygoni Cuspidati 20 ~ 30 parts, each component is dry, pulverized 10 ~ 30 mesh sieves, obtain coarse powder, by the described coarse powder mix homogeneously obtained, dry heat sterilization, pack, specification is 8 ~ 10g/ bag,
Step 2: prepare external medicine composition: the raw material components taking following parts by weight: Radix Polygoni Multiflori 50 ~ 80 parts, 30 ~ 60 parts, Semen sojae atricolor, Semen Sesami Nigrum 20 ~ 40 parts, the Radix Astragali 10 ~ 30 parts, Ganoderma 10 ~ 20 parts, 20 ~ 30 parts, Fructus Mori, Herba Ecliptae 15 ~ 30 parts, Fructus Psoraleae 10 ~ 30 parts, Cacumen Platycladi 15 ~ 35 parts, 20 ~ 40 parts, Folium Pini, Fructus Gleditsia 10 ~ 20 parts, 20 ~ 30 parts, the Radix Rehmanniae, Herba Menthae 10 ~ 15 parts, Fructus Tribuli 20 ~ 30 parts, coarse powder is ground into by after above-mentioned each component mixing, the ethanol that mass fraction is 50 ~ 75% is added in=described coarse powder and ethanol 1:8 (W/V) ratio, soak after 7 days, filter, leave filtrate and medicinal residues respectively, to add distilled water immersion in described medicinal residues after 12 ~ 24 hours, temperature fire heating 15 minutes, the volume ratio of described medicinal residues and described distilled water is 1:2 ~ 1:4, is cooled to room temperature, filters, obtains filtrate, the filtrate obtained twice is mixed into solution, adjust 5 times that described overall solution volume is described coarse powder volume, and the mass percent making ethanol account for described solution is 10 ~ 20%, then add mantoquita in above-mentioned filtrate, make the concentration of mantoquita in described external medicine composition be 0.02 ~ 0.06g/L.
7. the hair growth described in an any one of claim 1 ~ 6 also has the application method of the Chinese medicine composition of black hair function, it is characterized in that, described oral preparations Chinese medicine composition is brewed 10 ~ 15min through boiling boiled water, brew 8 ~ 10g at every turn, one day twice, after hair washing, described external medicine composition uniform application is also massaged gently in alopecia position and absorb completely to medicine for 5 ~ 10 minutes, each medication 4 ~ 7ml, every day 1 ~ 2 time.
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CN113499419A (en) * 2021-07-23 2021-10-15 青岛美芝生物技术有限公司 Traditional Chinese medicine composition for preventing hair loss, growing hair, controlling oil and removing dandruff

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