CN104800401A - Traditional Chinese medicine composition for treating rheumatic arthritis - Google Patents
Traditional Chinese medicine composition for treating rheumatic arthritis Download PDFInfo
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- 239000003814 drug Substances 0.000 title claims abstract description 20
- 239000000203 mixture Substances 0.000 title claims abstract description 11
- 201000003068 rheumatic fever Diseases 0.000 title abstract description 4
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 3
- 231100000862 numbness Toxicity 0.000 claims description 18
- 241000756943 Codonopsis Species 0.000 claims description 6
- 241001489978 Eupolyphaga Species 0.000 claims description 6
- 241000628997 Flos Species 0.000 claims description 6
- 239000009636 Huang Qi Substances 0.000 claims description 6
- 244000146493 Cryptotaenia japonica Species 0.000 abstract description 2
- 235000004035 Cryptotaenia japonica Nutrition 0.000 abstract description 2
- 241000502071 Halenia elliptica Species 0.000 abstract description 2
- 241000007126 Codonopsis pilosula Species 0.000 abstract 1
- 208000006820 Arthralgia Diseases 0.000 description 8
- 208000002193 Pain Diseases 0.000 description 7
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Abstract
The invention provides a traditional Chinese medicine composition for treating rheumatic arthritis. The traditional Chinese medicine composition is prepared from the following raw materials in part by weight: Halenia elliptica, Cryptotaenia japonica, codonopsis pilosula, radix paeoniae alba and the like. The traditional Chinese medicine composition can be used for treating the rheumatic arthritis.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition and the preparation method and application that treat rheumatism numbness.
Background technology
Rheumatism numbness waits exopathogen invasion because wind and cold is damp and hot, impatency meridians joint, QI-blood circulation is smooth, with general joint be migrans red, swell, weigh, pain is for main clinical manifestation.Normal finger rheumatic arthritis.Lack effective medicine at present.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine composition and the preparation method and application that treat rheumatism numbness.
Technical scheme: the object of the invention is by following scheme realize:
Treat a Chinese medicine composition for rheumatism numbness, it is prepared by the raw material of following parts by weight: Radix haleniae ellipticae 15 parts, Caulis et folium cryptotaeniae japonicae 12 parts, Radix Codonopsis 10 parts, the Radix Paeoniae Alba 10 parts, Eupolyphaga Seu Steleophaga 15 parts, Herba speranskiae tuberculatae 10 parts, Caulis Spatholobi 15 parts, the Radix Astragali 15 parts, Herba Asari 3 parts, Rhizoma Chuanxiong 10 parts, Flos Chrysanthemi 10 parts, Rhizoma Et Radix Notopterygii 10 parts, Ramulus Cinnamomi 6 parts, Radix Salviae Miltiorrhizae 15 parts, Ramulus Mori 10 parts, Fructus Lycii 15 parts, Radix Angelicae Pubescentis 10 parts, 5 parts, Radix Glycyrrhizae.
The application of Chinese medicine composition in the medicine of preparation treatment rheumatism numbness of described treatment rheumatism numbness.
In the present invention, Radix haleniae ellipticae is that Gentianaceae Herba Haleniae Corniculatae platymiscium purple spends anchor Halenia elliptica D.Don in vain, with root or all herbal medicine.Autumn excavates, and cleans and dries.Clearing away heat-damp and promoting diuresis, suppressing the hyperactive liver function of gallbladder promoting.For acute icterohepatitis, cholecystitis, gastritis, dizziness headache, toothache.The present invention is with all herbal medicine.Caulis et folium cryptotaeniae japonicae is the stem and leaf of samphire Caulis et folium cryptotaeniae japonicae.Formal name used at school CryptotaeniajaponicaHassk., antiinflammatory, removing toxic substances, invigorates blood circulation, detumescence.Control pneumonia, pulmonary abscess, gonorrhea, hernia, acute toothache, carbuncle furuncle swells, herpes zoster, skin pruritus.All the other medicines all meet standards of pharmacopoeia or are documented in Chinese medicine voluminous dictionary.
Beneficial effect: Radix haleniae ellipticae of the present invention, Caulis et folium cryptotaeniae japonicae clearing away heat-damp and promoting diuresis, promoting blood circulation and detumescence are monarch drug, Radix Codonopsis, the Radix Paeoniae Alba, Eupolyphaga Seu Steleophaga, Herba speranskiae tuberculatae, Caulis Spatholobi, the Radix Astragali, Herba Asari, Rhizoma Chuanxiong, Flos Chrysanthemi, Rhizoma Et Radix Notopterygii, Ramulus Cinnamomi, Radix Salviae Miltiorrhizae, Ramulus Mori, Fructus Lycii, Radix Angelicae Pubescentis blood circulation promoting and blood stasis dispelling, QI invigorating are ministerial drug, Radix Glycyrrhizae is adjuvant, coordinating the actions of various ingredients in a prescription, obtained medicine can safe and effective treatment rheumatism numbness.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1. prepare embodiment
1.1 take Radix haleniae ellipticae 15g, Caulis et folium cryptotaeniae japonicae 12g, Radix Codonopsis 10g, Radix Paeoniae Alba 10g, Eupolyphaga Seu Steleophaga 15g, Herba speranskiae tuberculatae 10g, Caulis Spatholobi 15g, Radix Astragali 15g, Herba Asari 3g, Rhizoma Chuanxiong 10g, Flos Chrysanthemi 10g, Rhizoma Et Radix Notopterygii 10g, Ramulus Cinnamomi 6g, Radix Salviae Miltiorrhizae 15g, Ramulus Mori 10g, Fructus Lycii 15g, Radix Angelicae Pubescentis 10g, Radix Glycyrrhizae 5g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.Be used for the treatment of rheumatism numbness.Oral, every bu is taken for twice sooner or later.
1.2 take Radix haleniae ellipticae 15g, Caulis et folium cryptotaeniae japonicae 12g, Radix Codonopsis 10g, Radix Paeoniae Alba 10g, Eupolyphaga Seu Steleophaga 15g, Herba speranskiae tuberculatae 10g, Caulis Spatholobi 15g, Radix Astragali 15g, Herba Asari 3g, Rhizoma Chuanxiong 10g, Flos Chrysanthemi 10g, Rhizoma Et Radix Notopterygii 10g, Ramulus Cinnamomi 6g, Radix Salviae Miltiorrhizae 15g, Ramulus Mori 10g, Fructus Lycii 15g, Radix Angelicae Pubescentis 10g, Radix Glycyrrhizae 5g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add 50g starch, technique is granulated routinely, must meet the granule of adult normal's 1 day consumption.Be used for the treatment of rheumatism numbness.Oral, every bu is taken for twice sooner or later.
1.3 take Radix haleniae ellipticae 15g, Caulis et folium cryptotaeniae japonicae 12g, Radix Codonopsis 10g, Radix Paeoniae Alba 10g, Eupolyphaga Seu Steleophaga 15g, Herba speranskiae tuberculatae 10g, Caulis Spatholobi 15g, Radix Astragali 15g, Herba Asari 3g, Rhizoma Chuanxiong 10g, Flos Chrysanthemi 10g, Rhizoma Et Radix Notopterygii 10g, Ramulus Cinnamomi 6g, Radix Salviae Miltiorrhizae 15g, Ramulus Mori 10g, Fructus Lycii 15g, Radix Angelicae Pubescentis 10g, Radix Glycyrrhizae 5g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, add 50g starch, technique is granulated routinely, and tabletting, can obtain the tablet meeting adult normal's 1 day consumption.Be used for the treatment of rheumatism numbness.Oral, every bu is taken for twice sooner or later.
2. the present invention is to the clinical research of rheumatism numbness
2.1 physical data: inventor collects the out-patient of 80 routine rheumatism numbness altogether between in January ,-2014 in April, 2013, age 46-68 year, course of disease 1-4.Be divided at random: treatment group 40 example, blank group 40 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2.2 diagnostic criterias:
2.2.1 walk to alter pain based on the large joint of extremity, companion weigh, miserable, numb, joint joint stuffiness.There is the disease such as aversion to cold, heating more.
2.2.2 there is pharyngalgia tonsillitis history before sick more, or paddle and drench with rain, occupy wetland history for a long time.
2.2.3 some patients can have low grade fever, extremity erythema iris, or erythema nodosum.Often can Cardiac Involvemant.
2.2.4 erythrocyte sedimentation rate speeds, and antistreptococcin " O " is greater than 500 units.
2.2.5 syndrome-classification
2.2.5.1 migratory arthralgia (ailment said due to cold or exposure wins partially): limbs joint myalgia, migration is indefinite, joint stuffiness, or sees fever with aversion to wind etc.Thin white fur of tongue, floating pulse.
2.2.5.2 arthralgia aggravated by cold (cold-evil wins partially): limbs joint pain is more acute, meets cold increasing the weight of, pain alleviated while getting warmth, and light night in daytime is heavy, and joint can not be bent and stretched, and sore spot is not red, and that touches is not hot.White, slippery and moist fur, stringy and tense pulse.
2.2.5.3 damp arthralgia (damp wins partially): limbs joint weighs aches, and sore spot is fixed, lower limb are very, or have swelling, numbness of the skin, and weather wet weather increases the weight of.White and greasy fur, relaxed and soft pulse.
2.2.5.4 pyretic arthralgia (pathogenic heat wins partially): onset is hurried, arthralgia, local is red and swollen scorching hot, and pain can not be touched, and joint stuffiness, obtains cold slightly easypro.There is fever and aversion to wind, hyperhidrosis, restlessness and thirst more.Red tongue with yellow fur, slippery and rapid pulse.
2.2.5.5 paralysis (QI and blood deficiency): with the passing of time the course of disease, does not heal repeatedly, arthralgia, time light time heavy.Yellowish complexion is simple and unadorned, cardiopalmus spontaneous perspiration, dizzy weak.Pale tongue, white and thin fur, soft pulse.
2.3 test method
2.3.1 the oral the present invention for the treatment of group is according to the obtained capsule of specific embodiment 1.1, sooner or later each once.30 days courses for the treatment of.
2.3.2 blank group oral placebo capsule, sooner or later respectively once.30 days courses for the treatment of.
2.4 criterions of therapeutical effect and therapeutic outcome
2.4.1 criterion of therapeutical effect
Recovery from illness: transference cure, joint motion is normal, and lab testing is normal.Take a turn for the better: symptom is clearly better, and lab testing is improved.Invalid: symptom and lab testing are without progress.
2.4.2 statistical result is treated in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 40 | 21 | 16 | 3 | 92.5 |
| Blank group | 40 | 0 | 1 | 39 | 2.5 |
Visible, the medicine that the present invention obtains can safe and effective treatment rheumatism numbness.
2.5 model case
Wang, man, 58 years old, it was main that pain is walked to alter in the large joint of extremity, and local is red and swollen scorching hot, and pain can not be touched, and joint stuffiness, obtains cold slightly easypro.There is fever and aversion to wind, hyperhidrosis, restlessness and thirst more.Red tongue with yellow fur, slippery and rapid pulse, is diagnosed as pyretic arthralgia, takes the capsule that the embodiment of the present invention 1.1 is obtained, and sooner or later respectively once, after 30 days, transference cure, joint motion is normal, and lab testing is normal.
Claims (2)
1. treat the Chinese medicine composition of rheumatism numbness for one kind, it is characterized in that, it is prepared by the raw material of following parts by weight: Radix haleniae ellipticae 15 parts, Caulis et folium cryptotaeniae japonicae 12 parts, Radix Codonopsis 10 parts, the Radix Paeoniae Alba 10 parts, Eupolyphaga Seu Steleophaga 15 parts, Herba speranskiae tuberculatae 10 parts, Caulis Spatholobi 15 parts, the Radix Astragali 15 parts, Herba Asari 3 parts, Rhizoma Chuanxiong 10 parts, Flos Chrysanthemi 10 parts, Rhizoma Et Radix Notopterygii 10 parts, Ramulus Cinnamomi 6 parts, Radix Salviae Miltiorrhizae 15 parts, Ramulus Mori 10 parts, Fructus Lycii 15 parts, Radix Angelicae Pubescentis 10 parts, 5 parts, Radix Glycyrrhizae.
2. treat the application of Chinese medicine composition in the medicine for the treatment of rheumatism numbness of rheumatism numbness as claimed in claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510190320.2A CN104800401A (en) | 2015-04-21 | 2015-04-21 | Traditional Chinese medicine composition for treating rheumatic arthritis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510190320.2A CN104800401A (en) | 2015-04-21 | 2015-04-21 | Traditional Chinese medicine composition for treating rheumatic arthritis |
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| CN104800401A true CN104800401A (en) | 2015-07-29 |
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| CN201510190320.2A Pending CN104800401A (en) | 2015-04-21 | 2015-04-21 | Traditional Chinese medicine composition for treating rheumatic arthritis |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1076120A (en) * | 1993-01-19 | 1993-09-15 | 王来运 | Medical liquid for relaxing tendons and joints |
| CN1124915A (en) * | 1994-03-31 | 1996-06-19 | 吉祥株式会社 | Hair curler |
-
2015
- 2015-04-21 CN CN201510190320.2A patent/CN104800401A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1076120A (en) * | 1993-01-19 | 1993-09-15 | 王来运 | Medical liquid for relaxing tendons and joints |
| CN1124915A (en) * | 1994-03-31 | 1996-06-19 | 吉祥株式会社 | Hair curler |
Non-Patent Citations (1)
| Title |
|---|
| 戴丽心: ""清热利湿活血综合疗法治疗活动期类风湿关节炎患者疗效分析"", 《中国现代药物应用》 * |
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