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CN104784641A - Traditional Chinese medicine preparation for treating liver cirrhosis disease - Google Patents

Traditional Chinese medicine preparation for treating liver cirrhosis disease Download PDF

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Publication number
CN104784641A
CN104784641A CN201510201642.2A CN201510201642A CN104784641A CN 104784641 A CN104784641 A CN 104784641A CN 201510201642 A CN201510201642 A CN 201510201642A CN 104784641 A CN104784641 A CN 104784641A
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China
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radix
chinese medicine
medicine preparation
traditional chinese
liver cirrhosis
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CN201510201642.2A
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Chinese (zh)
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陈玉龙
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Individual
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Abstract

The invention provides a traditional Chinese medicine preparation for treating liver cirrhosis diseases. The traditional Chinese medicine preparation mainly comprises the following medicinal materials: radix bupleuri, oldenlandia diffusa, radix curcumae, oriental wormwood, white paeony root, scutellaria baicalensis, cortex phellodendri, isatis root, folium isatidis, christina loosestrife herb, yellow chrysanthemum, peony tree roots and barks, fried atractylodes macrocephala, pericarpium citri reticulatae, radix aucklandiae, fried chicken's gizzard-membrane, tortoiseshell (honey-fried), radix polygoni multiflori preparata and fructus corni. The traditional Chinese medicine preparation is prepared through the steps of weighing the above medicines according to the ratio, and grinding the medicines into powder of 100-200 meshes. The traditional Chinese medicine preparation is based on the traditional Chinese medicine theory, and aiming at the nosogenesis of various liver cirrhosis diseases, traditional Chinese herbal medicines are finely selected to form the formula, and a medicine which has the functions of treating both symptoms and root causes, simultaneously treating and nourishing, calming the liver and nourishing the kidney and invigorating spleen to promote digestion can be prepared by using a scientific preparation method.

Description

A kind of Chinese medicine preparation for the treatment of liver cirrhosis disease
Technical field
The invention provides a kind of Chinese medicine preparation for the treatment of liver cirrhosis disease, relate to the medicine of hepatopathy, belong to Chinese medicine liver system disease technical field.
Background technology
The Chinese medicine preparation of current medical market treatment liver cirrhosis disease is a lot, and curative effect is very undesirable, can effectively symptom management develop few, that cures is less, and curative effect is unsatisfactory, and great majority are cured the symptoms, not the disease, fast few of drug effect, the case that curative effect is also unsatisfactory is a lot.
Summary of the invention
The present invention discloses a kind of Chinese medicine preparation for the treatment of liver cirrhosis disease, have drug effect obviously, have no side effect, treating both the principal and secondary aspects of a disease, short treating period, expense are low, cure rate is high, bounce-back less, easy and simple to handle, be easy to the feature such as oral.
the present invention discloses a kind of Chinese medicine preparation for the treatment of liver cirrhosis disease, is mainly made up by ratio of weight and the number of copies of following medicine:
Radix Bupleuri 17-30; Herba Hedyotidis Diffusae 28-40; Radix Curcumae 12-20; Herba Artemisiae Scopariae 13-20; Radix Paeoniae Alba 18-30; Radix Scutellariae 14-25; Cortex Phellodendri 13-20; Radix Isatidis 27-38; Folium Isatidis 29-35; Herba Lysimachiae 8-12; Herba Tagetis Patulae 14-20; Cortex Moutan 10-20; Rhizoma Atractylodis Macrocephalae (parched) 13-18; Radix Astragali 14-20; Pericarpium Citri Reticulatae 13-20; Radix Aucklandiae 10-20; Endothelium Corneum Gigeriae Galli (parched) 15-30; Carapax et Plastrum Testudinis (processing) 10-18; Radix Polygoni Multiflori Preparata 10-20; Fructus Corni 8-16.
a kind of Chinese medicine preparation for the treatment of liver cirrhosis disease provided by the invention, preferred prescription is:
Radix Bupleuri 25; Herba Hedyotidis Diffusae 35; Radix Curcumae 18; Herba Artemisiae Scopariae 15; The Radix Paeoniae Alba 25; Radix Scutellariae 20; Cortex Phellodendri 18; Radix Isatidis 30; Folium Isatidis 30; Herba Lysimachiae 10; Herba Tagetis Patulae 18; Cortex Moutan 18; Rhizoma Atractylodis Macrocephalae (parched) 15; The Radix Astragali 18; Pericarpium Citri Reticulatae 18; The Radix Aucklandiae 15; Endothelium Corneum Gigeriae Galli (parched) 25; Carapax et Plastrum Testudinis (processing) 15; Radix Polygoni Multiflori Preparata 15; Fructus Corni 15.
a kind of preparation method for the treatment of the Chinese medicine preparation of liver cirrhosis disease of the present invention is as follows:
Take in proportion with medicine-feeding, through 100-200 order fine powder, Chinese medicine preparation of the present invention can be obtained.
medicine of the present invention can make any preparation on pharmaceutics, as: the dosage forms such as powder, granule, tablet, capsule, pill.
the side of medicine of the present invention separates as follows:
In prescription, 20 taste Chinese medicines mostly are liver-smoothing, qi-regulating, heat-clearing and toxic substances removing, spleen invigorating repercussive, the medicine of suppressing the hyperactive liver the kidney invigorating.Wherein: Radix Bupleuri: hardship is put down, be slightly cold, reducing fever by reconciliation, soothing the liver yang invigorating; Herba Hedyotidis Diffusae: micro-hardship, cold, clearing heat, detoxicating, dispelling dampness; Two medicines are all monarch drug, share and can play: liver-smoothing, qi-regulating, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, the effect of removing heat from blood dampness removing.The 10 taste Chinese medicines such as Radix Curcumae, Herba Artemisiae Scopariae, the Radix Paeoniae Alba, Radix Scutellariae, Cortex Phellodendri, Radix Isatidis, Folium Isatidis, Herba Lysimachiae, Cortex Moutan are ministerial drug altogether, share and can strengthen: the liver soothing and the spleen invigorating, regulating QI to relieve pain, detumescence dissipating blood stasis, clearing away heat and cooling blood, suppressing the hyperactive liver improving eyesight, the effect of arresting bleeding and healing up ulcer.5 tastes such as Rhizoma Atractylodis Macrocephalae (parched), the Radix Astragali, Pericarpium Citri Reticulatae, the Radix Aucklandiae, Endothelium Corneum Gigeriae Galli (parched) share and can play: strengthening the spleen to promote digestion, promoting the circulation of QI to relieve pain, warming YANG and invigorating QI, the effect of antacid granulation promoting is adjuvant drug altogether.Carapax et Plastrum Testudinis (processing), Radix Polygoni Multiflori Preparata, Fructus Corni 3 taste share and can reach: enriching yin and nourishing kidney, suppressing the hyperactive liver kidney tonifying, nourish blood spermatogenesis, effect of bone and muscle strengthening, altogether for making medicine.Above 20 taste Chinese medicines share and can reach: liver-smoothing, qi-regulating, promoting blood circulation to remove blood stasis, heat-clearing and toxic substances removing, detumescence dampness removing, strengthening the spleen to promote digestion, promoting the circulation of QI to relieve pain, cooling blood for hemostasis, expelling pus and promoting granulation, effect of the liver and the kidney tonifying.
[usage and dosage] is oral, each 5 ~ 8 grams, 2 times on the 1st, and 15-30 minutes ante cibum, warm water delivery service, 15-30 days was 1 course for the treatment of.
[indication] various liver cirrhosis, also may be used for the symptom such as fatty liver, alcoholic liver hepatic injury.
the pharmacological evaluation of medicine of the present invention is as follows:
diagnosis basis:
(1) color ultrasound, CT.MRI diagnoses
(2) the various clinical symptoms of doctor trained in Western medicine
(3) differential diagnosis in tcm: stagnation of QI due to depression of the liver, the hepatic and renal YIN deficiency, deficiency of spleen-YANG and kidneyYANG, damp-heat accumulation, liver and spleen blood stasis defect.Cold-damp disturbing the spleen, phlegm and blood stasis, retention of dampness due to stagnation of QI.
Diagnostic criteria:
Cure: various clinical symptom disappearance;
Effective: various clinical symptoms is obviously improved;
Invalid: various clinical symptoms is without improvement;
Case: selected 136 routine various liver cirrhosis model cases, treats by taking medicine of the present invention, wherein cures 42 examples, cure rate 30.88%, effective 73 examples, effective percentage 53.68%, and invalid 21 examples, total effective rate is 84.56%.
good effect of the present invention is:based on China's Chinese medical theory, for the pathogenesis of various liver cirrhosis disease, selected pure herbal prescription, makes medicine by science, has treating both the principal and secondary aspects of a disease, controls and mends synchronously, suppressing the hyperactive liver the kidney invigorating, the effect of strengthening the spleen to promote digestion.Have short treating period, the features such as rapid-action, toxic and side effects is little, and expense is low, and obviously can improve life in patients, extend sufferer life, some patients can reach healing.
detailed description of the invention:
To be illustrated further description the present invention by following examples, and do not limit the present invention in any way, under the prerequisite not deviating from technical solution of the present invention, any change that those of ordinary skill in the art made for the present invention easily realize or change all will fall within right of the present invention.
embodiment 1
Take Radix Bupleuri 25g, Herba Hedyotidis Diffusae 35 g, Radix Curcumae 18 g, Herba Artemisiae Scopariae 15 g, the Radix Paeoniae Alba 25 g, Radix Scutellariae 20 g, Cortex Phellodendri 18g, Radix Isatidis 30 g, Folium Isatidis 30 g, Herba Lysimachiae 10 g, Herba Tagetis Patulae 18 g, Cortex Moutan 18 g, Rhizoma Atractylodis Macrocephalae (parched) 15 g, the Radix Astragali 18 g, Pericarpium Citri Reticulatae 18 g, the Radix Aucklandiae 15 g, Endothelium Corneum Gigeriae Galli (parched) 25 g, Carapax et Plastrum Testudinis (processing) 15 g, Radix Polygoni Multiflori Preparata 15 g, Fructus Corni 15 g respectively, remove impurity, be ground into 100-200 order fine powder, namely mix homogeneously obtains powder of the present invention.
embodiment 2
Radix Bupleuri 17g, Herba Hedyotidis Diffusae 28 g, Radix Curcumae 12 g, Herba Artemisiae Scopariae 13 g, the Radix Paeoniae Alba 18 g, Radix Scutellariae 14 g, Cortex Phellodendri 13 g, Radix Isatidis 27 g, Folium Isatidis 29 g, Herba Lysimachiae 8 g, Herba Tagetis Patulae 14 g, Cortex Moutan 10 g, Rhizoma Atractylodis Macrocephalae (parched) 13 g, the Radix Astragali 14 g, Pericarpium Citri Reticulatae 13 g, the Radix Aucklandiae 10 g, Endothelium Corneum Gigeriae Galli (parched) 15 g, Carapax et Plastrum Testudinis (processing) 10 g, Radix Polygoni Multiflori Preparata 10 g, Fructus Corni 8 g, remove impurity, be ground into 100-200 order fine powder, mix homogeneously, incapsulates agent and get final product.
embodiment 3
Radix Bupleuri 30g, Herba Hedyotidis Diffusae 40 g, Radix Curcumae 20 g, Herba Artemisiae Scopariae 20 g, the Radix Paeoniae Alba 30 g, Radix Scutellariae 25 g, Cortex Phellodendri 20 g, Radix Isatidis 38 g, Folium Isatidis 35 g, Herba Lysimachiae 12 g, Herba Tagetis Patulae 20 g, Cortex Moutan 20 g, Rhizoma Atractylodis Macrocephalae (parched) 18 g, the Radix Astragali 20 g, Pericarpium Citri Reticulatae 20 g, the Radix Aucklandiae 20 g, Endothelium Corneum Gigeriae Galli (parched) 30 g, Carapax et Plastrum Testudinis (processing) 18 g, Radix Polygoni Multiflori Preparata 20 g, Fructus Corni 16 g, remove impurity, be ground into 100-200 order fine powder, namely mix homogeneously obtains Chinese medicine preparation of the present invention.
the curative effect of medicine of the present invention is proved further by concrete clinical case:
case 1:
Zhao XX, man, 45 years old, before treatment: liver cirrhosis (++++), ascites (++++), portal hypertension (+++), vomiting (++), anemia (++).Through taking medicine prepared by the embodiment of the present invention 1, after treating two courses for the treatment of, liver cirrhosis (±), ascites (﹣), portal hypertension (﹣), anemia (﹣), vomiting (﹣).To follow up a case by regular visits to after 3 months and the coherence check state of an illness has no obvious development.
case 2:
Dong XX, female, 41 years old, before treatment: liver cirrhosis (++), ascites (++), portal hypertension (++), anemia (++).Through taking medicine prepared by the embodiment of the present invention 2, after treating two courses for the treatment of, liver cirrhosis (﹣), ascites (﹣), portal hypertension (﹣), anemia (+) are clearly better.Followed up a case by regular visits to through 4 months and coherence check change without exception, anemia (﹣) is cured.
case 3:
Open XX, man, 65 years old, before treatment: liver cirrhosis (+), anemia (+), stomach discomfort (+).Through taking medicine prepared by the embodiment of the present invention 3, after treating two courses for the treatment of, liver cirrhosis (﹣), anemia (﹣), stomach discomfort (﹣).
case 4:
Pottery XX, female, 38 years old, before treatment: liver cirrhosis (+++), ascites (++), portal hypertension (++), anemia (++).Through taking medicine prepared by the embodiment of the present invention 2, after treating three courses for the treatment of, liver cirrhosis (﹣), ascites (﹣), portal hypertension (﹣), anemia (+) are clearly better.Followed up a case by regular visits to through 4 months and coherence check change without exception, anemia (﹣) is cured.Followed up a case by regular visits to after 3 months and coherence check change without exception.

Claims (4)

1. treat a Chinese medicine preparation for liver cirrhosis disease, it is characterized in that mainly being made up by ratio of weight and the number of copies of following medicine:
Radix Bupleuri 17-30; Herba Hedyotidis Diffusae 28-40; Radix Curcumae 12-20; Herba Artemisiae Scopariae 13-20; Radix Paeoniae Alba 18-30; Radix Scutellariae 14-25; Cortex Phellodendri 13-20; Radix Isatidis 27-38; Folium Isatidis 29-35; Herba Lysimachiae 8-12; Herba Tagetis Patulae 14-20; Cortex Moutan 10-20; Rhizoma Atractylodis Macrocephalae (parched) 13-18; Radix Astragali 14-20; Pericarpium Citri Reticulatae 13-20; Radix Aucklandiae 10-20; Endothelium Corneum Gigeriae Galli (parched) 15-30; Carapax et Plastrum Testudinis (processing) 10-18; Radix Polygoni Multiflori Preparata 10-20; Fructus Corni 8-16.
2. a kind of Chinese medicine preparation for the treatment of liver cirrhosis disease as claimed in claim 1, preferred prescription is:
Radix Bupleuri 25; Herba Hedyotidis Diffusae 35; Radix Curcumae 18; Herba Artemisiae Scopariae 15; The Radix Paeoniae Alba 25; Radix Scutellariae 20; Cortex Phellodendri 18; Radix Isatidis 30; Folium Isatidis 30; Herba Lysimachiae 10; Herba Tagetis Patulae 18; Cortex Moutan 18; Rhizoma Atractylodis Macrocephalae (parched) 15; The Radix Astragali 18; Pericarpium Citri Reticulatae 18; The Radix Aucklandiae 15; Endothelium Corneum Gigeriae Galli (parched) 25; Carapax et Plastrum Testudinis (processing) 15; Radix Polygoni Multiflori Preparata 15; Fructus Corni 15.
3. the preparation method that a kind of as described in claim 1 and 2 treats the Chinese medicine preparation of liver cirrhosis disease is as follows:
Take in proportion to add medicine to, through 100-200 order fine powder, to obtain final product.
4. claim 1 or described a kind of Chinese medicine preparation for the treatment of liver cirrhosis disease, can make any preparation on pharmaceutics, as: the dosage forms such as powder, granule, tablet, capsule, pill.
CN201510201642.2A 2015-04-27 2015-04-27 Traditional Chinese medicine preparation for treating liver cirrhosis disease Pending CN104784641A (en)

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Application Number Priority Date Filing Date Title
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146903A (en) * 1995-07-12 1997-04-09 陈瑛 Prescription of Chinese medicine for treating cholecystitis, cholelithiasis, hepatitis and cholehepatocirrhosis
CN1303692A (en) * 2000-01-12 2001-07-18 陈有云 Toxin-discharging liver-fortifying medicine
CN101112591A (en) * 2007-08-04 2008-01-30 李五堂 Medicine for treating cirrhosis and production process thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146903A (en) * 1995-07-12 1997-04-09 陈瑛 Prescription of Chinese medicine for treating cholecystitis, cholelithiasis, hepatitis and cholehepatocirrhosis
CN1303692A (en) * 2000-01-12 2001-07-18 陈有云 Toxin-discharging liver-fortifying medicine
CN101112591A (en) * 2007-08-04 2008-01-30 李五堂 Medicine for treating cirrhosis and production process thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
张声生等: ""疏肝健脾化瘀解毒方治疗肝硬化活动期30例"", 《中国中西医结合消化杂志》 *
张成运等: ""中西医结合治疗肝硬化腹水20例疗效观察"", 《河北中医》 *
李彬之等: "《现代中医奇效良方宝典(上)》", 31 March 1996, 上海科学普及出版社 *
杨发周等: ""肝一方为主治疗肝炎后肝硬化84例临床观察"", 《新中医》 *

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Application publication date: 20150722