CN104784491A - Traditional Chinese medicine preparation for treating salpingitis of laying hens and preparation method thereof - Google Patents

Abstract

The invention provides a traditional Chinese medicine preparation for treating laying hen salpingitis and a preparation method thereof. The raw materials of the traditional Chinese medicine preparation include: Shuangshenzi, Huangteng, Pearl Ginseng, Yunzhi, Nepenthes, Abacus cotyledon, braid grass root, Moe, Begonia Root, Ishimi Chuan, Shubian Bamboo, Sweet Potato Vine, King Kong San, Black Face Leaf, Geranium, Goldenseal and Mountain Pepper Root. Beneficial effects of the present invention: the traditional Chinese medicine preparation of the present invention has the advantages of definite curative effect, no toxic and side effects, and no drug residues for the treatment of laying hens salpingitis, and can improve the laying rate of laying hens and enhance the physique and disease resistance of laying hens.

Description

A kind of traditional Chinese medicine preparation for treating laying hen salpingitis and preparation method thereof

technical field

The invention relates to a breeding animal feed additive containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating laying hen salpingitis and a preparation method thereof.

Background technique

Salpingitis of laying hens is a common disease of laying hens. Its clinical manifestations are various, but they all cause a decrease in the laying rate of laying hens. Thin-shell eggs, soft-shell eggs, sand-shell eggs, deformed eggs, and white-shell eggs , Small eggs increased as the main symptoms.

The infection of laying hen salpingitis is significantly different due to the differences in the level of feeding management, environmental sanitation, and prevention and control measures of the farmers, and the influence of factors such as whether there are other diseases secondary to it, resulting in higher morbidity and mortality of chicken salpingitis. big difference. Its cause of disease is more complicated, is one of frequently-occurring disease that threatens aquaculture, has also brought great influence to aquaculture simultaneously.

Cause of the disease: There are many reasons for the occurrence of this disease, such as poor sanitary conditions in the poultry house, the cloaca is polluted by bacteria (such as Salmonella pullorum, paratyphoid bacteria, Escherichia coli, etc.) and invades the oviduct; Eggs are too large or double-yolk eggs are produced, and sometimes the eggshell ruptures in the oviduct, which damages the oviduct; or excessive egg production, lack of vitamins A, D, and E in the feed can lead to salpingitis. Poultry suffers from salpingitis, which often causes tubal prolapse and dystocia. High-yielding hens born in the same year are prone to this disease.

Main symptoms: The appearance of the flock is normal, but there is no peak egg production period. The sick poultry infected with chicken salpingitis mainly manifests as pain and restlessness, difficulty in laying eggs and pain, and the egg shells of the eggs often have blood stains. Yellow and white pus-like secretions are often discharged from the fallopian tubes, polluting the feathers around the anus and below. With the development of the disease, the pain is uneasy, the body temperature rises, and sometimes it is lethargic, often lying on the ground, walking on the abdomen, and the sick poultry infected with chicken salpingitis starts to have a fever, and then the fever subsides, standing still, and drooping wings , The feathers are loose and messy, and some abdomens are on the ground or lethargic. When the inflammation spreads to the abdominal cavity, it can cause peritonitis, or rupture of the fallopian tubes can cause yolk peritonitis.

Contents of the invention

The technical problem to be solved by the present invention is to provide a traditional Chinese medicine preparation for treating laying hen salpingitis with definite curative effect, no toxic side effect and no drug residue and a preparation method thereof.

In order to solve the above-mentioned technical problems, the present invention provides a kind of traditional Chinese medicine preparation for the treatment of laying hen salpingitis. Braided Grass Root, Hemeng, Begonia Root, Ishimi Chuan, Tree Flat Bamboo, Sweet Potato Vine, King Kong San, Black Flour Leaf, Geranium, Kingsberry and Mountain Pepper Root.

Wherein, the weight-to-number ratio of each raw material of the traditional Chinese medicine preparation can be preferably as follows: 30-40 parts of Shuangshenzi, 40-50 parts of Huangteng, 20-30 parts of Pearl Ginseng, 10-20 parts of Yunzhi, Nepenthes 10 to 20 parts, 5 to 15 parts of abacus cotyledons, 15 to 25 parts of braided grass roots, 10 to 20 parts of Hemene, 20 to 30 parts of begonia roots, 30 to 40 parts of Ishimi Chuan, 10 to 20 parts of bamboo, sweet potatoes 20-30 parts of rattan, 5-15 parts of King Kong powder, 5-15 parts of black face leaves, 15-25 parts of geranium, 20-30 parts of golden plum and 10-20 parts of mountain pepper root.

Wherein, the weight-to-number ratio of each raw material of the traditional Chinese medicine preparation can be preferably as follows: 35-40 parts of Shuangshenzi, 45-50 parts of Huangteng, 25-30 parts of Pearl Ginseng, 15-20 parts of Yunzhi, Nepenthes 10-15 parts, 5-10 parts of abacus cotyledon, 20-25 parts of braided grass root, 10-15 parts of Hemeng, 25-30 parts of begonia root, 30-35 parts of Ishimi Chuan, 15-20 parts of bamboo, sweet potato 20-25 parts of rattan, 10-15 parts of King Kong powder, 5-10 parts of black face leaves, 15-20 parts of geranium, 25-30 parts of golden plum and 10-15 parts of mountain pepper root.

Wherein, the ratio of parts by weight of each raw material of the traditional Chinese medicine preparation can be preferably as follows: 36 parts of Shuangshenzi, 50 parts of Huangteng, 27 parts of Pearl Ginseng, 18 parts of Yunzhi, 12 parts of Nepenthes, 8 parts of abacus cotyledons, 24 parts of braided grass roots, 11 parts of Hemeng, 27 parts of Begonia roots, 34 parts of Ishimi Chuan, 15 parts of Shubianzhu, 23 parts of Sweet Potato Vine, 14 parts of King Kong powder, 6 parts of black face leaves, 17 parts of geranium, golden 28 parts of silk plum and 13 parts of mountain pepper root.

Wherein, the ratio of parts by weight of each raw material of the traditional Chinese medicine preparation can be preferably as follows: 39 parts of Shuangshenzi, 47 parts of Huangteng, 28 parts of Pearl Ginseng, 16 parts of Yunzhi, 15 parts of Nepenthes, 5 parts of abacus cotyledons, 22 parts of braided grass roots, 13 parts of Hemeng, 29 parts of begonia roots, 32 parts of Ishimi Chuan, 19 parts of tree flat bamboo, 25 parts of sweet potato vines, 11 parts of King Kong powder, 9 parts of black face leaves, 18 parts of geranium, golden 26 parts of silk plum and 14 parts of mountain pepper root.

Wherein, when the dosage form of described Chinese medicine preparation is powder, its preparation method comprises the following steps:

The first step is to mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 65-75% relative to the mass of the mixture, heat and reflux for 2-4 hours, extract, and filter to obtain the first extraction liquid; the medicinal dregs obtained by filtering are then added with ethanol having an alcohol concentration of 2 to 4 times the mass of the medicinal dregs and are 85 to 95% ethanol, heated and refluxed for 1 to 3 hours, extracted, and filtered to obtain a second extract; the first The extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1 to 2 hours, pulverized, and sieved to obtain an ultrafine powder of 300 mesh to 400 mesh;

In the third step, add starch 2 to 4 times the mass of the superfine powder obtained in the second step, and mix to obtain a powder.

Wherein, when the dosage form of the Chinese medicine preparation is an oral liquid, its preparation method comprises the following steps:

The first step is to mix Shuangshenzi, Huangteng, Pearl Ginseng, Yunzhi, Nepenthes, Abacus cotyledons, braid grass roots, Hemeng and Begonia roots in proportion, and use methanol with an alcohol concentration of 70% to 80% as a solvent , use the percolation method to slowly percolate at a speed of 1-3ml per minute, collect the percolation liquid, concentrate under reduced pressure and dry to obtain a dry paste, which is ground into 200-300 mesh powder, and the quality of the added methanol is the first 3 to 5 times the mass of the mixture;

In the second step, the remaining raw medicinal materials are mixed in proportion and crushed into powders of 100-200 mesh;

In the third step, add distilled water 3 to 6 times the mass of the powder obtained in the second step to the powder obtained in the second step, decoct for 2 to 4 hours, and filter to obtain the first filtrate; add the filter residue to the Distilled water with 2 to 4 times its mass is decocted for 1 to 2 hours, filtered to obtain the second filtrate; combine the first and second filtrates, concentrate to remove 2/3 to 3/4 volume of water, add alcohol Ethanol with a concentration of 90% to 95%, so that the alcohol concentration reaches 70% to 80%, let it stand for 12 to 24 hours, filter, concentrate under reduced pressure, dry to obtain a dry paste, and grind it into a powder of 200 to 300 meshes;

The fourth step is to mix the powder obtained in the first step and the third step, add distilled water 3 to 5 times the mass of the mixed powder, 0.1 to 0.3 times sucrose, and 0.01 to 0.02 times sodium benzoate, stir, and boil. Cool, filter, subpackage, and sterilize to obtain the oral liquid.

Beneficial effects of the present invention: the traditional Chinese medicine preparation of the present invention has the advantages of definite curative effect, not easy to relapse, no toxic and side effects, and no drug residues for the treatment of laying hens salpingitis, and can improve the egg production rate and good egg rate of laying hens, and enhance the efficiency of laying hens. physical fitness and disease resistance.

Detailed ways

The invention provides a traditional Chinese medicine preparation for treating laying hen salpingitis. The raw materials of the traditional Chinese medicine preparation include: Shuangshenzi, Huangteng, Pearl Ginseng, Yunzhi, Nepenthes, Abacus cotyledon, braided grass root, Hemeng, Begonia root , Shi Jianchuan, Shubianzhu, Sweet Potato Vine, Vajrasan, Black Face Leaf, Geranium, Goldenseal and Mountain Pepper Root.

The pharmacology of each crude drug in the described Chinese medicine is as follows:

Double Kidneys: [alias] Swan with Egg, Jade Phoenix Flower Root, Paired Ginseng, Double Yellow Ginseng, Double Kidney Ginseng, Old Hen with Egg, Golden Goose with Egg, Sheep Kidney Ginseng, Diamond Ruyi, Paired Ginseng, Pianzhui Medicine, chicken egg ginseng, mountain ivory, kidney seven. [Source] The source of medicinal materials: it is the tuber of the orchid plant Yufenghua. [nature and flavor] sweet; Bitter; Flat. [return through] lung; Kidney channel. [function cures mainly] invigorating the kidney and benefiting the lung; promoting dampness; detoxification. Mainly used for kidney deficiency, lumbago, impotence, tuberculosis and cough, edema, excessive leucorrhea, hernia, carbuncle, furunculosis, snake bites. [Discussions of various schools] 1. "Jiangxi Herbal Medicine": Disperses Qi and detoxifies. 2. "Kunming Common Herbal Medicine": Nourishing lung and kidney, diuretic, anti-inflammatory. 3. "Yunnan Simao Chinese Herbal Medicine Selection": nourishing, relieving cough and reducing phlegm. Control orchitis, salpingitis, physical weakness cough. [Excerpt] "Chinese Materia Medica"

Huangteng: [alias] Huanglian, Huanglianteng, Shenjinteng, Shandawang, Dahuangsteng, Tianxianteng, Golden Key. 【Source】The base source of medicinal materials: the rhizome or leaves of Phantasia chinensis. [nature and flavor] bitter; cold in nature. [return through] the heart; Liver Channel. [function cures mainly] heat-clearing and toxic substances removing; Dampness promoting. Mainly acute tonsillitis, pharyngitis, upper respiratory tract infection; conjunctivitis; jaundice; gastroenteritis; dysentery; indigestion in children; food poisoning; salpingitis; acute and chronic endometritis; acute pelvic inflammatory disease; vaginitis; Burns. [Excerpt] "Chinese Materia Medica"

Pearl Ginseng: [Source] This product is Panax japonicus C.A.Mey.var.major (Burk.) C.Y.Wu et K.M.Feng or Panax japonicus (Bamboo Root Panax, Twister Seven, Coptidis notoginseng , Mosaic notoginseng) the dried rhizome of Panax japonicusC.A.Mey.var.bipinnatifidus (seem.) C.Y.Wu et K.M.Feng. Excavated in autumn, removed the rough bark and fibrous roots, dried; or steamed (boiled) thoroughly and then dried. [nature and flavor] bitter, sweet, slightly cold. [return through] returns liver, lung, stomach warp. [Functions and Indications] Tonifying the lung, nourishing yin, activating collaterals, and stopping bleeding. Used for deficiency of both qi and yin, dysphoria and thirst, consumptive cough, injury from falls, arthralgia, hemoptysis, hematemesis, traumatic bleeding. [Excerpt] "Chinese Pharmacopoeia"

Versicolor versicolor: [alias] variegated versicolor versicolor, yellow versicolor, gray versicolor, varroa fungus, coriolus versicolor, multi-color boletus, red see hand, Melaleuca versicolor, colorful versicolor versicolor. [Source] Jiyuan of medicinal materials: it is the fruiting body of Coriolus versicolor, a fungus of Polyporaceae. Latin plant animal mineral name: Coriolus versicolor (L.exFr.) Quel. [Polystictus versicolor (L.) Fr.]. Harvesting and storage: It can be harvested throughout the year, remove impurities and sun-dry. [nature and flavor] sweet; light; slightly cold. [return through] liver; spleen; lung meridian. [functions and indications] invigorating the spleen and promoting dampness; relieving cough and relieving asthma; clearing heat and detoxifying; antitumor. Main chronic active hepatitis; liver cirrhosis; chronic bronchitis; spastic bronchitis in children; sore throat; various tumors; rheumatoid arthritis; leukemia. [Excerpt] "Chinese Materia Medica"

Nepenthes: [alias] pitcher plant, monkey cheng, piglet cage, water bucket, monkey cage, doll bottle. [Source] Medicinal material Jiyuan: stems and leaves of Nepenthes plant Nepenthes. Latin plant animal mineral name: Nepenthes mirabilis (Lour.) Druce. Harvest and storage: Harvest in autumn, cut into sections and dry in the sun. [nature and flavor] sweet; light; cool. [return through] lung; Gall bladder; Stomach warp. [Functions and Indications] Moisturizing the lung and relieving cough; Mainly used for hemoptysis due to dryness of the lungs; common cold and cough; whooping cough; jaundice; dysentery; urinary calculi; can also be used for gastric and duodenal ulcers; [Discussions by various experts] 1. "Lu Chuan Materia Medica": anti-inflammatory, detoxification, water drainage, treatment of edema, dysentery, sore carbuncle, ulcer redness, insect bites, and treatment of traumatic injuries. 2. "Guangdong Traditional Chinese Medicine" Ⅱ: Clear dry fire in the lungs and cure hemoptysis. 3. "Handbook of Commonly Used Chinese Herbal Medicine" by the Guangzhou Army: clearing heat and dampness, reducing phlegm and relieving cough. Treatment of icteric hepatitis, stomach and duodenal ulcer pain, urinary tract stones, high blood pressure, cold cough, whooping cough. [Excerpt] "Chinese Materia Medica"

Abacus cotyledon: [source] from "Jiangxi folk herbal medicine". [alias] wild pumpkin leaves. 【Source】The source of medicinal materials: the leaves of Glochidion puberum (L.) Hutch. Latin plant animal mineral name: Glochidion puberum(L.) Huteh.[Agy neia pubera L.]. Harvesting and storage: Harvested in summer and autumn, used fresh or dried for later use. [nature and flavor] bitter; astringent; cool in nature; slightly poisonous. [return through] large intestine channel. [Functions and Indications] Clearing heat and promoting dampness; detoxifying and reducing swelling. Damp-heat diarrhea; jaundice; stranguria; leukorrhagia; fever; [Discussions by various schools] 1. "Guangxi Traditional Chinese Medicine Chronicles": dampness-reducing, blood-removing, detoxification of lacquer poison and snake venom. Treat lacquer sores, red and white dysentery, bruises, snake bites. 2. "Guangdong Traditional Chinese Medicine" Ⅱ: Eliminates stagnation, removes dampness, clears away heat, relaxes tendons and activates collaterals. Treat dysentery, cold, flu, excessive physical fatigue, rat and snake bites. [Excerpt] "Chinese Materia Medica"

Braid grass roots: [source] from "Yunnan Chinese Herbal Medicine". [alias] Climbing incense; Xiaoye Sandian Jingen. [Source] Medicinal material base source: the root of the leguminous plant Desmodium microphylLum (Thunb.) DC. Latin plant animal mineral name: Desmodium microphyllum (Thunb.) DC.[Hedysarum microphyllum Thunb.]. Harvesting and storage: Harvested in summer and autumn, used fresh or sun-dried. [nature and flavor] sweet; bitter; cool. [return through] liver; bladder; large intestine channel. [functions and indications] clearing heat and promoting dampness; relieving cough and relieving asthma; reducing swelling and detoxifying. Main stone stranguria; stomach pain; jaundice; dysentery; cough; asthma; malnutrition in children; poisonous snake bites; carbuncle sores scrofula; paint sores; hemorrhoids. [Discussions by various experts] 1. "Yunnan Chinese Herbal Medicine": anti-inflammatory and hemostasis, dampness and collaterals. Treat postpartum bleeding, red metrorrhagia and leucorrhea, amenorrhea, weakness and night sweats, dysentery, rheumatism, urinary tract infection, hemorrhoids, rectal prolapse, bruises. 2. Jiangxi "Herbal Medicine Handbook": clearing away heat and improving eyesight. [Excerpt] "Chinese Materia Medica"

Hemeng: [Source] From "Chinese Medicine Plants". [English name] Common Aeschynomene Herb, Herb of Common Aeschynomene. [Aliases] water antler, Hemingcao, water saponin, wood pai bean, wood barnyardgrass, single tree root, wild saponin, comb tree, wild mimosa, centipede willow, wild locust tree, night close door, grass sickle, Wild orchid, wild duck tree grass, wild bean, wild bean, sea willow, latian grass. 【Source】The source of the medicinal material: it is the aerial part of the leguminous plant Saponaria japonica. Latin plant animal mineral name: Aeschynomene indica L. Harvesting and storage: Harvesting in September-October, harvesting the aboveground parts, fresh or sun-dried. [nature and flavor] sweet and bitter; cold; nontoxic. [return through] lung; Stomach warp. [Functions and Indications] Clearing heat and promoting dampness, expelling wind and improving eyesight, clearing milk. Mainly hot stranguria, bloody stranguria, edema, diarrhea, boils, scabies, conjunctival congestion, swelling and pain, cloudy eyes, night blindness, joint pain, and lack of milk in puerpera. [Discussions by various experts] 1. "Supplements to Materia Medica": Mainly hot shower, red and astringent urine, and children's scoliosis. Improving eyesight, entering the water, stopping bleeding and dysentery. Pound the juice and take it. 2. "Plant Research on Plant Names and Facts": To remove wind and kill insects. 3. "Tianbao Materia Medica": eliminate wind, remove swelling. Treatment of rickets, jaundice, swelling poison. 4. "Classified Herbal Medicine": Treat swelling. Steam chicken, diuresis and drench. 5. "Handbook of Commonly Used Chinese Herbal Medicine" by the Guangzhou Army: clearing away heat and eliminating stagnation. Treat flatulence, indigestion, gastritis pain, wind-heat cold, eczema, dermatitis. 6. "Jiangxi Herbal Medicine": clearing away heat and dampness, reducing swelling and stopping bleeding. [Excerpt] "Chinese Materia Medica"

Begonia root: [source] from "Guizhou Folk Medicine Collection". [Aliases] A mouthful of blood, golden thread hanging gourd, red and white two pills, rock balls. [Source] Medicinal material Jiyuan: It is the root of Begoniaceae plant Begonia. Latin plant, animal and mineral name: Begonia evansiana Andr. Harvesting and storage: can be harvested throughout the year; dig the roots; wash; use fresh; or slice and dry. [nature and flavor] sour; astringent. [function cures mainly] blood stasis dispelling; Hemostasis; Clearing heat and promoting diuresis. Indicates bruises; hematemesis, hemoptysis; epistaxis; knife wound bleeding; metrorrhagia; blood stasis amenorrhea; irregular menstruation; [Each discussion] 1 "Classified Herbal Medicine": Control hematemesis, bruises. 2. "Guizhou Folk Prescriptions and Medicines Collection": Stop vomiting blood, hemoptysis, and bleeding from knife wounds. 3. "Shaanxi Chinese Herbal Medicine": promoting blood circulation and dispelling blood stasis, clearing away heat, stopping bleeding and relieving pain. Control bruises, hematemesis, epistaxis, gastric ulcer, dysentery, pulmonary abscess, metrorrhagia, leucorrhea, irregular menstruation. 4. "Guizhou Herbal Medicine": promoting blood circulation and removing blood stasis, cooling blood to stop bleeding. 5. Jiangxi "Herbal Medicine Handbook": Promoting qi and blood circulation, reducing swelling and relieving pain, antispasmodic, and treating scrofula. [Excerpt] "Chinese Materia Medica"

Shi Jianchuan: [Source] From "Compendium". [Aliases] Purple ginseng, Wufenghua, Xiaodanshen, Yuexiahong, Wushacao, Momianfeng, sweating, stone piercing, Shi Dachuan, Shanzhenna, Zidanhua, red root ginseng, banzhilian, Tian Celery, blood herb. [Source] Medicinal material base source: It is the whole herb of Lamiaceae plant Sage sinensis. Latin plant animal mineral name: Salvia chinensis Benth. Harvesting and storage: Harvest and cut whole grass during flowering period, use fresh or sun-dried. [nature and flavor] acrid in the mouth; bitter; slightly cold in nature. [return through] returns liver; Spleen channel. [functions and indications] promoting blood circulation and removing blood stasis; clearing heat and promoting dampness; dispelling stagnation and detumescence. Mainly irregular menstruation; dysmenorrhea; amenorrhea; uterine bleeding, blood in the stool; damp-heat jaundice; heat-toxin bloody dysentery; stranguria; Injured and swollen. [Excerpt] "Chinese Materia Medica"

Tree flat bamboo: [source] from "Yunnan Simao Chinese Herbal Medicine Selection". [Aliases] Swallowtail flat bamboo orchid, fish tail grass, tree bamboo, mouse tail, stone flat orchid, wild flat bamboo, stone flat bamboo, hairy mouse tail. [Source] Medicinal material base source: It is the whole plant of Orchidaceae orchid. Latin plant animal mineral name: Oberonia iridifolia (Roxb.) Lindl.[Cymbidium iridifolium Roxb.]. Harvesting and storage: It can be harvested throughout the year, scalded in boiling water and dried in the sun. [nature and flavor] slightly bitter; cool in nature. [return through] bladder channel. [functions and indications] clearing heat and promoting dampness; promoting blood circulation and dredging collaterals. Main urinary tract infection; bronchitis; asthma; enteritis; indigestion; bruises; fractures. [Excerpt] "Chinese Materia Medica"

Sweet potato vine: [Source] Published in "Guizhou Folk Medicine Collection". [Aliases] crossing the river dragon, earth melon, ground centipede, crossing mountain dragon, ox horse vine, crossing stone dragon, paving the ground centipede, sweet potato stem, Niutuobi, blocking the road tiger, ground fungus, wild sweet potato vine, frost slope tiger, creeping ground Milk, Zhandilong, Mandijin, Floor Rattan, Loquat, Wannian Grilled. [Source] The source of medicinal materials: the stems and leaves of the moraceae plant Ficus pachyrhiza. Latin plant, animal and mineral name: Ficus tikoua Bur. Harvest and storage: Harvest in September-October, wash and dry. [nature and flavor] bitter in the mouth; cold in nature. [Functions and Indications] Clearing heat and promoting dampness; promoting blood circulation and dredging collaterals; detoxifying and reducing swelling. Indicates cough due to lung heat; dysentery; edema; jaundice; indigestion in children; rheumatism pain; amenorrhea; [Excerpt] "Chinese Materia Medica"

King Kong San: [Source] From "Yunnan Chinese Herbal Medicine". [Aliases] Akamutong, wild apple root, five-clawed gold, wild grape root, jade grape root, gun anther, five-clawed dragon, broken stone beads, red sow vine, big bone pill, flying centipede vine, see swelling, Red vine, red neixiao, red vine, black blood vine, clover vine, red dog poplar. [Source] Medicinal material Jiyuan: it is the root or vine of Vitis trifidae. Latin plant, animal and mineral name: Ampelopsis delavayana (Franch.) Planch. [Vitis delavayana Franch.] Harvesting and storage: Harvest stems and vines in summer and autumn, dig roots in autumn, wash, slice separately, and dry or dry. [nature and flavor] pungent; light; astringent; flat. [return through] the heart; Liver Channel. [Functions and Indications] Clearing heat and promoting dampness; promoting blood circulation and dredging collaterals; stopping bleeding and promoting granulation; detoxifying and reducing swelling. Mainly stranguria syndrome; white turbidity; hernia; partial fall; rheumatic arthralgia; bruises and bruises; traumatic bleeding; burns; sores and carbuncles. [Discussions by various experts] 1. "Shaanxi Chinese Herbal Medicine": detumescence and detoxification, hemostasis and pain relief, evacuation of pus and regeneration of muscles, and expelling rheumatism. Control bruises, fractures, rheumatoid arthritis, rheumatic lumbago, hematochezia, metrorrhagia, leucorrhea. 2. "Pharmaceutical Bulletin": Treat water and fire burns, wounds, vomiting and diarrhea, chronic ulcers and skin injuries caused by erosive gas. (1960, 8(2):63). 3. "Yunnan Traditional Chinese Medicine Proved Prescription": hemostasis, pain relief, antiseptic, anti-inflammatory, pulling out pus and promoting granulation. Treat broken bones and broken skin, sores and pains, water and fire burns. 4. "Sichuan Commonly Used Chinese Herbal Medicine": Treat bruises, gold wounds, knife wounds, carbuncles, malignant sores, swelling and toxins, Fengdu Youdan. [Excerpt] "Chinese Materia Medica"

Black face leaf: [source] from "Guangzhou Air Force Commonly Used Chinese Herbal Medicine Handbook". [Aliases] Tanaka Kui, Four Eyed Leaf, Night Orchid Tea, Iron Armored General, Old Crow Writing, Temple Doll, Chicken Kidney Leaf, Pot Cover Boy, Black Lacquer Mortar, Green Lacquer, Mountain Village Orchid, Mountain Osmanthus, Lacquer Grass, Monkey Writing , wild beets. [Source] Medicinal material Jiyuan: It is the young branches and leaves of Euphorbiaceae plant black face leaf. Latin plant animal mineral name: Breynia fruticosa(L.) Hook.f.[Andrachne fruticosa L.]. Harvesting and storage: Harvested throughout the year, dried or used fresh. [nature and flavor] slightly bitter taste; cool in nature; poisonous. [return through] large intestine; liver channel. [functions and indications] clearing away heat and dampness; promoting blood circulation and detoxification. Indicates abdominal pain, vomiting and diarrhea; eczema; waist-wrapping fire pill; dermatitis; paint sores; rheumatic arthralgia; [Excerpt] "Chinese Materia Medica"

Geranium: [source] from "Compendium of Materia Medica Supplements". [Aliases] Five-leaf clover, old official grass, five-petal flower, old guancao, Tiangang grass, five-leaf couplet, broken copper coin, old raven tendon, guanjin, five-tooth cake, old raven beak, quail beak. 【Source】The source of medicinal materials: it is the whole plant of Geranium geranium, Geranium geranium, Siberian geranium, Nepal geranium, root geranium with fruit of Geranium geranium. Harvesting and storage: when the fruit is about to mature in summer and autumn, cut the aboveground part or pull up the whole plant, remove the soil and impurities, and dry in the sun. [nature and flavor] bitter in the mouth; slightly pungent; flat in nature. [return through] spleen; Bladder channel. [function cures mainly] expelling wind and dredging collaterals; promoting blood circulation; clearing heat and promoting dampness. Main rheumatic arthralgia; skin numbness; muscle and bone aches and pains; bruises; diarrhea and dysentery; sores. [Discussions by various experts] 1. "Southern Yunnan Materia Medica": Dispelling various winds and itchy skin. Treat muscle and bone pain, phlegm-fire flaccidity and softness, spasms of hands and feet, numbness, diuresis, purging accumulated heat in the bladder, attacking and dispersing all sores and swollen toxins, reducing tuberculosis fever and fever, treating diseases such as wind and fire, tooth decay, pox rash and scabies. 2. "Supplements to Compendium": remove wind, dredge meridians and activate blood circulation, strengthen muscles and bones, and dredge collaterals. Control injury, arthralgia, numbness, skin wind, soak in wine and drink often. 3. "Modern Practical Chinese Medicine": Stop chronic dysentery, thicken the stomach, regulate the middle and strengthen the spleen. 4. "Guizhou Folk Prescription Collection": treat bruises, stop bleeding from knife wounds, relieve cough, and benefit lung qi. 5. "Materia Medica": heat-clearing and toxic substances removing. Control fever and quench one's thirst, carbuncle sores. [Excerpt] "Chinese Materia Medica"

Gold silk plum: [alias] hypericum peach, pig's thumb willow, forsythia, awn seed flower, yellow flower fragrance, mountain gardenia, broken bowl flower, crossing road yellow, big leaf yellow, big field edge yellow, yellow wood, golden fragrance, Dragon Boat Festival flowers. 【Source】It is the whole plant of Garcinia Chrysanthemum. Latin plant animal mineral name: Hypericum patulumThunb.ex Murray[Norysca patula(Thunb.exMurray)J.Voigt]. Harvest and storage: Collect in summer, wash, chop, and sun-dry. [nature and flavor] bitter; cold. [return through] liver; Kidney; Bladder channel. [function cures mainly] heat-clearing and damp-damp detoxification; Soothing the liver and dredging collaterals; Mainly damp-heat gonorrhea; hepatitis; common cold; tonsillitis; [Excerpt] "Chinese Materia Medica"

Mountain Pepper Root: [Source] From "Fujian Folk Herbal Medicine". [Aliases] Beef tendon strip root, beef tendon tree root, Lei Gonggao, Hongyechai, golden oak. [Source] Medicinal material base source: the root of the camphor plant of Lauraceae. Latin plant animal mineral name: Lindera glauca (Sieb. et Zucc.) Bl. Harvest and storage: Harvest in autumn and sun-dry. [nature and flavor] pungent; warm; bitter. [return through] liver; Stomach warp. [Functions and Indications] Dispelling wind and dredging collaterals; regulating qi and promoting blood circulation; promoting dampness and reducing swelling; reducing phlegm and relieving cough. Main rheumatic arthralgia; bruises; epigastric pain; debilitating overwork; bronchitis; edema. [Excerpt] "Chinese Materia Medica", "Dictionary of Chinese Medicine"

Wherein, the weight-to-number ratio of each raw material of the traditional Chinese medicine preparation can be preferably as follows: 30-40 parts of Shuangshenzi, 40-50 parts of Huangteng, 20-30 parts of Pearl Ginseng, 10-20 parts of Yunzhi, Nepenthes 10 to 20 parts, 5 to 15 parts of abacus cotyledons, 15 to 25 parts of braided grass roots, 10 to 20 parts of Hemene, 20 to 30 parts of begonia roots, 30 to 40 parts of Ishimi Chuan, 10 to 20 parts of bamboo, sweet potatoes 20-30 parts of rattan, 5-15 parts of King Kong powder, 5-15 parts of black face leaves, 15-25 parts of geranium, 20-30 parts of golden plum and 10-20 parts of mountain pepper root.

Wherein, the weight-to-number ratio of each raw material of the traditional Chinese medicine preparation can be preferably as follows: 35-40 parts of Shuangshenzi, 45-50 parts of Huangteng, 25-30 parts of Pearl Ginseng, 15-20 parts of Yunzhi, Nepenthes 10-15 parts, 5-10 parts of abacus cotyledon, 20-25 parts of braided grass root, 10-15 parts of Hemeng, 25-30 parts of begonia root, 30-35 parts of Ishimi Chuan, 15-20 parts of bamboo, sweet potato 20-25 parts of rattan, 10-15 parts of King Kong powder, 5-10 parts of black face leaves, 15-20 parts of geranium, 25-30 parts of golden plum and 10-15 parts of mountain pepper root.

Wherein, the ratio of parts by weight of each raw material of the traditional Chinese medicine preparation can be preferably as follows: 36 parts of Shuangshenzi, 50 parts of Huangteng, 27 parts of Pearl Ginseng, 18 parts of Yunzhi, 12 parts of Nepenthes, 8 parts of abacus cotyledons, 24 parts of braided grass roots, 11 parts of Hemeng, 27 parts of Begonia roots, 34 parts of Ishimi Chuan, 15 parts of Shubianzhu, 23 parts of Sweet Potato Vine, 14 parts of King Kong powder, 6 parts of black face leaves, 17 parts of geranium, golden 28 parts of silk plum and 13 parts of mountain pepper root.

Wherein, the ratio of parts by weight of each raw material of the traditional Chinese medicine preparation can be preferably as follows: 39 parts of Shuangshenzi, 47 parts of Huangteng, 28 parts of Pearl Ginseng, 16 parts of Yunzhi, 15 parts of Nepenthes, 5 parts of abacus cotyledons, 22 parts of braided grass roots, 13 parts of Hemeng, 29 parts of begonia roots, 32 parts of Ishimi Chuan, 19 parts of tree flat bamboo, 25 parts of sweet potato vines, 11 parts of King Kong powder, 9 parts of black face leaves, 18 parts of geranium, golden 26 parts of silk plum and 14 parts of mountain pepper root.

Wherein, when the dosage form of described Chinese medicine preparation is powder, its preparation method comprises the following steps:

The first step is to mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 65-75% relative to the mass of the mixture, heat and reflux for 2-4 hours, extract, and filter to obtain the first extraction liquid; the medicinal dregs obtained by filtering are then added with ethanol having an alcohol concentration of 2 to 4 times the mass of the medicinal dregs and are 85 to 95% ethanol, heated and refluxed for 1 to 3 hours, extracted, and filtered to obtain a second extract; the first The extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1 to 2 hours, pulverized, and sieved to obtain an ultrafine powder of 300 mesh to 400 mesh;

In the third step, add starch 2 to 4 times the mass of the superfine powder obtained in the second step, and mix to obtain a powder.

Wherein, when the dosage form of the Chinese medicine preparation is an oral liquid, its preparation method comprises the following steps:

The first step is to mix Shuangshenzi, Huangteng, Pearl Ginseng, Yunzhi, Nepenthes, Abacus cotyledons, braid grass roots, Hemeng and Begonia roots in proportion, and use methanol with an alcohol concentration of 70% to 80% as a solvent , use the percolation method to slowly percolate at a speed of 1-3ml per minute, collect the percolation liquid, concentrate under reduced pressure and dry to obtain a dry paste, which is ground into 200-300 mesh powder, and the quality of the added methanol is the first 3 to 5 times the mass of the mixture;

In the second step, the remaining raw medicinal materials are mixed in proportion and crushed into powders of 100-200 mesh;

In the third step, add distilled water 3 to 6 times the mass of the powder obtained in the second step to the powder obtained in the second step, decoct for 2 to 4 hours, and filter to obtain the first filtrate; add the filter residue to the Distilled water with 2 to 4 times its mass is decocted for 1 to 2 hours, filtered to obtain the second filtrate; combine the first and second filtrates, concentrate to remove 2/3 to 3/4 volume of water, add alcohol Ethanol with a concentration of 90% to 95%, so that the alcohol concentration reaches 70% to 80%, let it stand for 12 to 24 hours, filter, concentrate under reduced pressure, dry to obtain a dry paste, and grind it into a powder of 200 to 300 meshes;

The fourth step is to mix the powder obtained in the first step and the third step, add distilled water 3 to 5 times the mass of the mixed powder, 0.1 to 0.3 times sucrose, and 0.01 to 0.02 times sodium benzoate, stir, and boil. Cool, filter, subpackage, and sterilize to obtain the oral liquid.

The following examples are used to describe the implementation of the present invention in detail, so as to fully understand how the present invention uses technical means to solve technical problems, achieve technical effects and implement accordingly.

Embodiment 1: Powder

Take Shuangshenzi 360g, Huangteng 500g, Pearl Ginseng 270g, Yunzhi 180g, Nepenthes 120g, Abacus cotyledon 80g, Braid grass root 240g, Hemeng 110g, Begonia root 270g, Ishimi Chuan 340g, Bamboo 150g, sweet potato 230g rattan, 140g diamond powder, 60g black face leaf, 170g geranium, 280g golden plum and 130g mountain pepper root.

Its preparation method comprises the following steps:

In the first step, the raw materials of the traditional Chinese medicine preparation are mixed in proportion, and ethanol with an alcohol concentration of 70% relative to the mass of the mixture is added to 6 times, heated and refluxed for 4 hours, extracted, and filtered to obtain the first extract; Add ethanol with an alcohol concentration of 95% to the dregs, which is 3 times the mass of the dregs, heat and reflux for 2 hours, extract, and filter to obtain the second extract; combine the first extract and the second extract, and concentrate under reduced pressure Remove the ethanol solvent and dry to obtain a dry paste;

In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 2 hours, pulverized, and sieved to obtain a 400-mesh ultrafine powder;

In the third step, add starch 3.4 times its mass to the superfine powder obtained in the second step, and mix to obtain a powder.

Embodiment 2: oral liquid

Take 390g Shuangshenzi, 470g Huangteng, 280g Pearl Ginseng, 160g Yunzhi, 150g Nepenthes, 50g Abacus cotyledon, 220g Braid grass root, 130g Hemeng, 290g Begonia root, 320g Ishimi Chuan, 190g Twig bamboo, sweet potato 250g rattan, 110g diamond powder, 90g black face leaf, 180g geranium, 260g golden plum and 140g mountain pepper root.

Its preparation method comprises the following steps:

In the first step, Shuangshenzi, Huangteng, Pearl Ginseng, Yunzhi, Nepenthes, Abacus cotyledon, braid grass root, Hemeng and Begonia root are mixed in proportion, and methanol with an alcohol concentration of 80% is used as a solvent. The rolling method slowly percolates at a speed of 2ml per minute, collects the percolation liquid, concentrates under reduced pressure and dries to obtain a dry paste, which is ground into a 300-mesh powder, and the quality of the added methanol is 4.5 times that of the mixture in the first step;

In the second step, the remaining raw medicinal materials are mixed in proportion and crushed into 200-mesh powder;

In the third step, add distilled water 5 times the mass of the powder obtained in the second step to the powder obtained in the second step, decoct for 3 hours, and filter to obtain the first filtrate; add the filter residue 3 times the mass distilled water, decocted for 2 hours, and filtered to obtain the second filtrate; combined the first filtrate and the second filtrate, concentrated 2/3 volume of water, and added ethanol with an alcohol concentration of 90% to make the alcohol concentration reach 75% %, stand still for 20 hours, filter, concentrate under reduced pressure, and dry to obtain a dry paste, which is ground into a 300-mesh powder;

The fourth step is to mix the powder obtained in the first step and the third step, add distilled water, 0.25 times sucrose, and 0.015 times sodium benzoate relative to the mass of the mixed powder, stir, boil, cool, filter, and pack , and sterilize to obtain oral liquid.

Toxicity test:

Acute toxicity test: 70 mice, half male and half female, weighing 20-26 g, were used for acute toxicity test. Mice are divided into two groups at random, i.e. control group and administration group, fasting 12 hours before experiment, the Chinese medicine powder prepared by the embodiment of the present invention 1 is dissolved in water, (concentration is 15.54g crude drug/ml, highest concentration) Gavage, the volume of gavage is 5ml/kg (that is, the single administration dose is 77.7 crude drug/kg), the control group is given an equal amount of normal saline, administered 2 times a day, with an interval of 6 hours between administrations, continuous observation after administration After 14 days, the toxic reaction and death number of the mice were recorded. The results of the experiment showed that compared with the control group, there was no significant difference in the mice after administration. After 14 days of continuous observation in the experiment, the general condition, diet, drinking water, and weight gain of the mice were all normal. Mice were orally administered the powder of the present invention with LD50>77.7 crude drug/kg, and the maximum daily dosage was 155.4 crude drug/kg/day. The clinical dosage of the traditional Chinese medicine of the present invention is 2.4g crude drug/day/chicken, and the weight of adult laying hens is 1.8KG, and the average dosage is 1.333g crude drug/kg/day. By body weight: the tolerated dose of the traditional Chinese medicine of the present invention is 117 times of the clinical dosage in mice (average body weight is 23g). Therefore, the traditional Chinese medicine of the present invention has low acute toxicity and is safe for clinical use.

Long-term toxicity test: Chinese medicine embodiment 1 powder of the present invention is to mice by 4.82,9.32 and 17.42g crude drug/kg continuous medication 15 weeks (1.0ml/100g body weight, every day 2 times) and after drug withdrawal 3 weeks, the result shows: the The invention of traditional Chinese medicine has no obvious effect on the hair, behavior, defecation, body weight, organ weight, blood picture, liver and kidney function, blood sugar, blood lipid and other indicators of mice. After 15 weeks and 3 weeks after stopping the drug, there was no obvious change in the organs of the mice. It shows that the traditional Chinese medicine of the present invention has little toxicity to mice after long-term administration, and there is no abnormal reaction after drug withdrawal, so the application is safe.

clinical experiments:

Experimental animals: 1,750 Roman laying hens from a professional chicken farmer in the suburbs of Linyi City. In June 2014, most of the chickens suffered from pain and restlessness, difficulty in laying eggs and pain, and most of the eggs produced had blood stains on the eggshells. Yellow and white pus-like secretions are often discharged from the fallopian tubes, polluting the feathers around the anus and below. In some serious cases, the body temperature rises, and sometimes it is lethargic, lying on the ground, walking on the abdomen, standing still, drooping wings, and fluffy feathers. Diagnosed as salpingitis. 1254 sick animals were randomly divided into two groups, an experimental group (654 animals) and a control group (600 animals). The experimental chickens were raised in cages, with free access to food and water, and conventional feeding and management.

experimental method:

Experimental group: 2 days of routine feeding first. Then drink water normally, add the traditional Chinese medicine powder of the embodiment 1 of the present invention in the ratio of 2.5% in the basal feed for feeding, stir evenly, and feed continuously for 5 days.

Control group: the animals were fed routinely for 2 days. Mixed drinking: egg health (Hebei Yunfa Animal Pharmaceutical Co., Ltd.), according to every 100g mixed with 1000L of water, 1-2 times a day, continuous feeding for 5 days; mixed feeding: add the following ingredients to the basic feed: 100kg of basal feed was added with 70g egg-poultry multi-ovalin (Bolan Pharmaceutical Branch of Henan Xinxiang Boyang Animal Husbandry Group) and 100g egg Fu (Bolan Pharmaceutical Branch of Henan Xinxiang Boyang Animal Husbandry Group), and fed for 5 consecutive days.

Observe the statistical indicators: observe the feed intake of the chickens every day, record the number of eggs produced, the number of broken eggs, soft eggs, and deformed eggs, etc., and count the indicators such as feed intake, egg production rate, and broken egg rate of each group.

Efficacy criteria: cured: egg production and good egg rate returned to normal, mental condition is good, feathers are normal, fallopian tubes have no pus-like secretions; effective: egg production and good egg rate have improved significantly, mental state is good, fallopian tubes have no pus-like secretions Secretion; Ineffective: Egg production and good egg rate basically did not change, the mental state did not improve significantly, and the fallopian tube still had pus-like secretions. Among them, the effective rate is the percentage of the cured number and the effective number in the total.

Treatment results: see Table 1 for statistical results of treatment before and after treatment; see Table 2 for statistical results of egg production rate and good egg rate before and after treatment.

Table 1 The comparison of treatment before and after treatment is as follows:

group Healed (only) valid (only) invalid (only) Efficient(%) test group 482 142 30 95.4% control group 308 195 97 83.8%

As can be seen from the data in Table 1, compared with the control group, using the medicament of the embodiment of the present invention to treat chicken salpingitis has the advantages of significant curative effect and high cure rate.

At the same time, in the following two months, 482 laying hens cured in the experimental group and 308 laying hens cured in the control group were followed up for 2 months. The results showed that 11 relapsed in the treatment group, and the recurrence rate was 2.28%. 48, the recurrence rate was 15.58%. The difference was statistically significant (p<0.05), and the recurrence rate of the experimental group was lower than that of the control group.

Table 2 The comparison of egg production rate and good egg rate before and after treatment is as follows:

As can be seen from the data in Table 2, the medicine of the embodiment of the present invention, compared with the control group, can better improve the egg production, egg production rate and good egg rate of sick chickens; The egg production rate can be obviously recovered, and the abnormal eggs such as sandy eggs, soft eggs, and small eggs are significantly reduced, and the egg production rate and good egg rate can be restored to the pre-disease state in about 5 days, or even worse than the pre-disease state. good.

The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention to other forms. Any skilled person who is familiar with this profession may use the technical content disclosed above to change or modify the equivalent of equivalent changes. Example. However, any simple modifications, equivalent changes and modifications made to the above embodiments according to the technical essence of the present invention without departing from the content of the technical solution of the present invention still belong to the protection scope of the technical solution of the present invention.

Claims (9)

1. a Chinese medicine preparation for the treatment of laying hen salpingitis, characterized in that, each raw material of the Chinese medicine preparation comprises: Shuangshenzi, Huangteng, Pearl Ginseng, Yunzhi, Nepenthes, abacus cotyledons, braid grass roots, Moe, Begonia Root, Ishimi Chuan, Shubian Bamboo, Sweet Potato Vine, King Kong San, Black Face Leaf, Geranium, Goldenseal and Mountain Pepper Root. 2. The traditional Chinese medicine preparation according to claim 1, characterized in that, the parts by weight of each raw material of the Chinese medicinal preparation are as follows: 30-40 parts of Shuangshenzi, 40-50 parts of Huangteng, 20-30 parts of Pearl Ginseng 10-20 parts of Versicolor versicolor, 10-20 parts of Nepenthes, 5-15 parts of abacus cotyledons, 15-25 parts of braid grass roots, 10-20 parts of Hemeng, 20-30 parts of Begonia roots, 30-30 parts of Ishimi Chuan 40 parts, 10-20 parts of bamboo, 20-30 parts of sweet potato vine, 5-15 parts of King Kong powder, 5-15 parts of black face leaves, 15-25 parts of geranium, 20-30 parts of goldenseal and mountain 10-20 parts of pepper root. 3. The traditional Chinese medicine preparation according to claim 1 or 2, characterized in that, the ratios by weight of each raw material of the Chinese medicine preparation are as follows: 35-40 parts of Shuangshenzi, 45-50 parts of Huangteng, 25 parts of Zhuzi Ginseng ~30 parts, Versicolor versicolor 15~20 parts, Nepenthes 10~15 parts, Abacus cotyledon 5~10 parts, Braid grass root 20~25 parts, Hemeng 10~15 parts, Begonia root 25~30 parts, Ishimi Chuan 30-35 parts, 15-20 parts of bamboo, 20-25 parts of sweet potato vine, 10-15 parts of diamond powder, 5-10 parts of black face leaf, 15-20 parts of geranium, 25-30 parts of goldenseal and 10-15 parts of mountain pepper root. 4. The traditional Chinese medicine preparation according to claims 1 to 3, characterized in that, the parts by weight of the raw materials of the Chinese medicine preparation are as follows: 36 parts of Shuangshenzi, 50 parts of Huangteng, 27 parts of Pearl Ginseng, Yunzhi 18 parts, 12 parts of Nepenthes, 8 parts of abacus cotyledons, 24 parts of braided grass roots, 11 parts of Hemeng, 27 parts of Begonia roots, 34 parts of Ishimi Chuan, 15 parts of Bamboo, 23 parts of Sweet Potato Vine, 14 parts of King Kong San , 6 parts of black face leaves, 17 parts of geranium, 28 parts of golden plum and 13 parts of mountain pepper root. 5. The traditional Chinese medicine preparation according to claims 1 to 3, characterized in that, the parts by weight of the raw materials of the Chinese medicine preparation are as follows: 39 parts of Shuangshenzi, 47 parts of Huangteng, 28 parts of Pearl Ginseng, Yunzhi 16 parts, 15 parts of Nepenthes, 5 parts of abacus cotyledons, 22 parts of braided grass roots, 13 parts of Hemeng, 29 parts of Begonia roots, 32 parts of Ishimi Chuan, 19 parts of Bamboo, 25 parts of Sweet Potato Vine, 11 parts of King Kong San , 9 parts of black face leaves, 18 parts of geranium, 26 parts of golden plum and 14 parts of mountain pepper root. 6. Chinese medicine preparation as claimed in claim 1 to 5 is characterized in that, the dosage form of described Chinese medicine preparation is a powder, and its preparation method comprises the following steps: The first step is to mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 65-75% relative to the mass of the mixture, heat and reflux for 2-4 hours, extract, and filter to obtain the first extraction liquid; the medicinal dregs obtained by filtering are then added with ethanol having an alcohol concentration of 2 to 4 times the mass of the medicinal dregs and are 85 to 95% ethanol, heated and refluxed for 1 to 3 hours, extracted, and filtered to obtain a second extract; the first The extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste; In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1 to 2 hours, pulverized, and sieved to obtain an ultrafine powder of 300 mesh to 400 mesh; In the third step, add starch 2 to 4 times the mass of the superfine powder obtained in the second step, and mix to obtain a powder. 7. Chinese medicine preparation as claimed in claim 1 to 6, is characterized in that, the dosage form of described Chinese medicine preparation is oral liquid, and its preparation method comprises the following steps: The first step is to mix Shuangshenzi, Huangteng, Pearl Ginseng, Yunzhi, Nepenthes, Abacus cotyledons, braid grass roots, Hemeng and Begonia roots in proportion, and use methanol with an alcohol concentration of 70% to 80% as a solvent , use the percolation method to slowly percolate at a speed of 1-3ml per minute, collect the percolation liquid, concentrate under reduced pressure and dry to obtain a dry paste, which is ground into 200-300 mesh powder, and the quality of the added methanol is the first 3 to 5 times the mass of the mixture; In the second step, the remaining raw medicinal materials are mixed in proportion and crushed into powders of 100-200 mesh; In the third step, add distilled water 3 to 6 times the mass of the powder obtained in the second step to the powder obtained in the second step, decoct for 2 to 4 hours, and filter to obtain the first filtrate; add the filter residue to the Distilled water with 2 to 4 times its mass is decocted for 1 to 2 hours, filtered to obtain the second filtrate; combine the first and second filtrates, concentrate to remove 2/3 to 3/4 volume of water, add alcohol Ethanol with a concentration of 90% to 95%, so that the alcohol concentration reaches 70% to 80%, let it stand for 12 to 24 hours, filter, concentrate under reduced pressure, dry to obtain a dry paste, and grind it into a powder of 200 to 300 meshes; The fourth step is to mix the powder obtained in the first step and the third step, add distilled water 3 to 5 times the mass of the mixed powder, 0.1 to 0.3 times sucrose, and 0.01 to 0.02 times sodium benzoate, stir, and boil. Cool, filter, subpackage, and sterilize to obtain the oral liquid. 8. a preparation method of the described Chinese medicine preparation of claims 1 to 5, is characterized in that, the dosage form of described Chinese medicine preparation is a powder, and its preparation method may further comprise the steps: The first step is to mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 65-75% relative to the mass of the mixture, heat and reflux for 2-4 hours, extract, and filter to obtain the first extraction liquid; the medicinal dregs obtained by filtering are then added with ethanol having an alcohol concentration of 2 to 4 times the mass of the medicinal dregs and are 85 to 95% ethanol, heated and refluxed for 1 to 3 hours, extracted, and filtered to obtain a second extract; the first The extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste; In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1 to 2 hours, pulverized, and sieved to obtain an ultrafine powder of 300 mesh to 400 mesh; In the third step, add starch 2 to 4 times the mass of the superfine powder obtained in the second step, and mix to obtain a powder. 9. a preparation method of Chinese medicine preparation described in claims 1 to 5, characterized in that, the dosage form of said Chinese medicine preparation is an oral liquid, and its preparation method may further comprise the steps: The first step is to mix Shuangshenzi, Huangteng, Pearl Ginseng, Yunzhi, Nepenthes, Abacus cotyledons, braid grass roots, Hemeng and Begonia roots in proportion, and use methanol with an alcohol concentration of 70% to 80% as a solvent , use the percolation method to slowly percolate at a speed of 1-3ml per minute, collect the percolation liquid, concentrate under reduced pressure and dry to obtain a dry paste, which is ground into 200-300 mesh powder, and the quality of the added methanol is the first 3 to 5 times the mass of the mixture; In the second step, the remaining raw medicinal materials are mixed in proportion and crushed into powders of 100-200 mesh; In the third step, add distilled water 3 to 6 times the mass of the powder obtained in the second step to the powder obtained in the second step, decoct for 2 to 4 hours, and filter to obtain the first filtrate; add the filter residue to the Distilled water with 2 to 4 times its mass is decocted for 1 to 2 hours, filtered to obtain the second filtrate; combine the first and second filtrates, concentrate to remove 2/3 to 3/4 volume of water, add alcohol Ethanol with a concentration of 90% to 95%, so that the alcohol concentration reaches 70% to 80%, let it stand for 12 to 24 hours, filter, concentrate under reduced pressure, dry to obtain a dry paste, and grind it into a powder of 200 to 300 meshes; In the fourth step, mix the powders obtained in the first step and the third step, add distilled water 3 to 5 times the mass of the mixed powder, 0.1 to 0.3 times sucrose, and 0.01 to 0.02 times sodium benzoate, stir, and boil. Cool, filter, subpackage, and sterilize to obtain the oral liquid.