CN104757022A - Sterilizing composition containing prochloraz and bio-sourced bactericide and application thereof - Google Patents
Sterilizing composition containing prochloraz and bio-sourced bactericide and application thereof Download PDFInfo
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- CN104757022A CN104757022A CN201510116776.4A CN201510116776A CN104757022A CN 104757022 A CN104757022 A CN 104757022A CN 201510116776 A CN201510116776 A CN 201510116776A CN 104757022 A CN104757022 A CN 104757022A
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- composition
- prochloraz
- disease
- bactericidal
- lentinan
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- 239000000203 mixture Substances 0.000 title claims abstract description 91
- 239000005820 Prochloraz Substances 0.000 title claims abstract description 67
- TVLSRXXIMLFWEO-UHFFFAOYSA-N prochloraz Chemical compound C1=CN=CN1C(=O)N(CCC)CCOC1=C(Cl)C=C(Cl)C=C1Cl TVLSRXXIMLFWEO-UHFFFAOYSA-N 0.000 title claims abstract description 67
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 35
- 239000003899 bactericide agent Substances 0.000 title abstract description 14
- 230000001954 sterilising effect Effects 0.000 title abstract 7
- 201000010099 disease Diseases 0.000 claims description 38
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 38
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 23
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- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims description 10
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- 241000700605 Viruses Species 0.000 claims description 10
- 238000002360 preparation method Methods 0.000 claims description 9
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- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 claims description 4
- 230000001580 bacterial effect Effects 0.000 claims description 4
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Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the field of pesticides and relates to a sterilizing composition containing prochloraz and a bio-sourced bactericide and an application thereof. The sterilizing composition contains two active components, one is the prochloraz and the other is harpin protein, wherein the weight ratio of the first active component to the second active component is 1-80:1-50. The total weight of both the prochloraz and the harpin protein accounts for 2-80% by weight of the sterilizing composition. In the invention, the prochloraz achieves the sterilizing effect by means of inhibition of ergosterol biosynthesis and the second active component is a bio-sourced product, so that the compounding mechanism of the sterilizing composition is complex and individual and the compounded two active components are free of conflict. The compounded two active components have a synergistic interaction so that the sterilizing composition is reduced in use amount and cost.
Description
Division explanation
The application is the applying date is 2012-8-4, and application number is 2012102769688, the divisional application of the Chinese invention patent application that name is called " a kind of bactericidal composition and application thereof containing Prochloraz and biogenic bactericide ".
Technical field:
The invention belongs to pesticide field, relate to a kind of bactericidal composition and the application thereof that contain Prochloraz and biogenic bactericide.
Background technology
Prochloraz (prochloraz), chemical name: N-propyl group-N-[2-(2,4,6-Trichlorophenoxy) ethyl]-imidazoles-1-formamide, structural formula is as follows:
Prochloraz is a kind of wide spectrum, low toxicity bactericide, has obvious preventive effect to the disease that various crop is caused by sac fungi and imperfect fungus, also can be mixed with most of bactericide, bactericide, Insecticides (tech) & Herbicides (tech), all has good control efficiency.Prochloraz has Uptake and translocation, prevention & protection, the multiple actions such as treatment, to field crop, fruit and vegetable, multiple diseases on turf and ornamental plants has treatment and eradicant action, conventional use can be used for preventing and treating the conventional use water prevention rice bakanae disease, rice blast, false smut, citrus anthracnose, blossom-end rot, penicilliosis, green mould, banana anthracnose, leaf spot, mango anthracnose, leaf spot of peanut, capsicum, eggplant, muskmelon, the vegetables anthracnose such as tomato, Strawberry anthracnose, sclerotinia rot of colza, leaf spot, mushroom brown spot, apple anthracnose, pear scab etc., Prochloraz is also widely used in the fields such as fruit freshness preserving.
Amino-oligosaccharide: as marine biological preparation; derive from ocean; chitin from marine organisms shell; through a kind of oligosaccharide kind novel biopesticide that deacetylated and enzymic degradation obtain; various plants fungal disease and virus disease can be prevented and treated; amino-oligosaccharide as biopesticide diseases prevention and disease-resistant in have number of mechanisms; except as activation signal molecule; inducing plant body produces outside resistance; also can be used as plant growth regulator; promote plant cell activation, stimulating plant grows, and possesses the function of the fertile economic benefits and social benefits of medicine.Plant produces chitinase by absorption amino-oligosaccharide and pathogen interacts, suppress growth of pathogenic bacteria, make disease plant produce system resistant, promote induction biosynthesis protective plant protecting agent, excite synthesis and the accumulation of plant lignin, can promote that again disease resistance of plant enzymes activity improves simultaneously.Because plant produces system resistant, stem foot vascular bundle obviously alleviates without pathology or pathology, well developed root system, and plant is sturdy, and individual plant Fresh Yuxincao increases, and premunition improves.The amino-oligosaccharide mechanism of action is unique, result of use does not have chemicals performance so obvious in a short time, what also do not have chemical pesticide to show is so fast, so do not praised highly by peasant and means of agricultural production dealer always,, from the angle of environmental protection and the safety of food, and the life and health to the following mankind, use the meaning of amino-oligosaccharide in agricultural production just very great, it brings revolution will to the agricultural of China, become substituting of high-toxic pesticide, and gradually accept by people, be also the inevitable choice of in the future agricultural disease control.
Portugal's polyene sugar: crop system can be induced to obtain the motivating factor of disease resistance, show distinctive biologic activity: on the one hand, crop can be induced to produce the disease resistance of excellent broad spectrum, with regard to virus disease, the early stage of the multiple diseases such as mosaic virus not only can be suppressed surely to grow, breed and expand, and can also the viral long extended distance of the external former suppression of virus of passivation crop.Crop carry out Portugal's polyene sugar spray process after, viral time of occurrence rather late in newborn blade, and occurring degree is very low.Also significant control efficiency is had for other diseases such as celery wilt disease, cucumber damping off, root rot tomato virus disease, graw mold of tomato etc.Meanwhile, polyene sugar in Portugal's also can be used for the storage of crops, extends the freshness date of vegetables fruit, and can keep the original local flavor of fruit.Portugal polyene sugar as biopesticide except have outstanding behaviours in control crop virosis except, diseases prevention and disease-resistant in have number of mechanisms, it can discharge a kind of signal, stimulates induction to make object and produces resistance; In addition, as crop growth regulator, can also promote that crop cell activates, stimulating growth.Meanwhile, polyene sugar in Portugal's has direct killing action to crop pathogens, and it can directly be adsorbed on germ cell surface on the one hand, forms the Obstruct membrane of one deck polymer substance, stops nutriment to intracellular transport; Directly can penetrate in germ cyton on the other hand, directly upset the normal physiological activity of cell.
Mushroom proteoglycan: extract from edible microbial fermentation solution, there is bioactive material, belong to pure biologic product, its main component is mushroom polysaccharide, structure is by glucose, mannose, galactose, wood sugar hang with protein fragments, both there is very strong suppression and killing action, had again obvious disease-resistant yield-increasing, improved the effect of crop quality.The former medicine of mushroom proteoglycan is off-white powder, water-soluble, and preparation is dark brown liquid, free from extraneous odour, is not easy to Basic pesticides and uses with.For preventing and treating the virus disease of the various crop such as paddy rice, tomato, capsicum, cucumber, tobacco, potato, flowers, mixed with the bactericide of antifungal have good preventive and therapeutic effect to fungal disease.Mushroom proteoglycan is the material that medicine and agricultural chemicals all have application, is applied to medicine the earliest, starts in recent years to be applied to agricultural chemicals.Being applied to agricultural chemicals at present and only having lentinan, is adopt mushroom to carry out a kind of polysaccharide fermenting, be separated, purify.
Harpin albumen: the non-specific exciton being phytopathogen hrp gene code, has proved that most cause of disease Harpin albumen energy evoking tobacco, potato, tomato, soybean, cucumber and arabidopsis produce allergy.This albumen, in 2000 at U.S. Register and merchandized handling, is mainly used in the multiple diseases such as control black shank, grape grey mould, potato leaf pinta.
Summary of the invention:
The object of the invention is that the problems such as and pathogen resistance undesirable for current single dose effect provide a kind of applied widely, cost is low, the effective bactericidal composition containing Prochloraz and biogenic bactericide.
A further object of the invention is to provide the application of this bactericidal composition.
The object of the invention is to be realized by following measures:
A kind of bactericidal composition, containing two kinds of active components, wherein the first composition is Prochloraz, second composition be selected from following biogenic microbiocidal composition any one: mushroom proteoglycan, amino-oligosaccharide, Portugal's polyene sugar, oligosaccharide, harpin albumen, the weight ratio of the first composition and the second composition is 1 ~ 80:1 ~ 50, preferably 5 ~ 50:1 ~ 50, further preferably 0.5 ~ 50:1, most preferably 1 ~ 10:1.
The gross weight percentage composition that both first composition Prochloraz and the second ingredients Biogenic source bactericide account for composition is 2-80%, preferred 5-50%, further preferred 8-40%.
Described bactericidal composition with the first composition and the second composition for principle active component and insecticides adjuvant, excipients are mixed with any one formulation that agricultural chemicals allows.
Described bactericidal composition, one wherein in Prochloraz and following biogenic bactericide: mushroom proteoglycan, amino-oligosaccharide, Portugal's polyene sugar, oligosaccharide, harpin albumen, both and known auxiliary agent and excipient are re-dubbed any one formulation that agricultural chemicals allows.These known auxiliary agents, excipients have dispersant, diffusant, defoamer, wetting agent, disintegrant etc.Auxiliary agent can adopt calcium dodecyl benzene sulfonate, alkylphenol polyoxyethylene, the rare block compound of polyoxyethylene polyoxy third (as agriculture breast 33
#), one or more combinations in polyoxyethylene nonylphenol ether, excipient comprises cyclohexanone, dimethylbenzene, solvent naphtha, water, antifreezing agent (as propane diols), deionized water etc.Above auxiliary agent, excipient and other auxiliary material can be alone or and use.
Described formulation is missible oil, suspending agent, aqueous emulsion, wetting powder, microemulsion or water dispersion granule etc.
The application of described bactericidal composition in the medicine of preparation control fungal diseases of plants, especially applies in the medicine of preparation control Cereal, melon and fruit or vegetable crop rice blast, false smut, bakanae disease of rice, rice sheath blight disease, anthracnose, leaf spot, stalk break, bacterial wilt, epidemic disease, penicilliosis, scab, fusarium wilt, wither here disease, damping off, root rot, tomato virus disease or gray mold.
" % " of the present invention is mass percent.
Mushroom proteoglycan of the present invention, amino-oligosaccharide, Portugal's polyene sugar, oligosaccharide, harpin albumen can conventionally be made by oneself, also can commercially availablely buy.The consumption of the second composition of the present invention refers to the consumption of active ingredient.
Beneficial effect of the present invention:
1, the Prochloraz that the present invention is used plays bactericidal action by suppressing ergosterol biosynthesis, and the second composition is biological product-derived, complicated mechanism, uniqueness, and mutual mixture can not produce low touching, can Synergistic, reduces dosage, reduces costs.
2, the present composition scope of application increases, be applicable to the crop pest of preventing and treating Cereal, various melon and fruit, vegetables, particularly prevent and treat the crop pests such as paddy rice, wheat, tomato, capsicum, cucumber, tobacco, potato, flowers, fruit tree, as rice blast, false smut, bakanae disease of rice, rice sheath blight disease and anthracnose, leaf spot, stalk break, bacterial wilt, epidemic disease, penicilliosis, scab, fusarium wilt, wither here cereal, melon and fruit and the vegetable disease such as disease, damping off, root rot, tomato virus disease, gray mold.
3, bactericidal composition of the present invention has good control efficiency to sac fungi, basidiomycetes, imperfect fungus fungal disease and virus disease; The employing of mix preparation effectively can reduce the usage amount of single variety, reduces Selective Pressure, therefore can suppress or alleviate the drug-fast generation of disease to unitary agent.
Embodiment
Below in conjunction with embodiment, the invention will be further described, and in embodiment, the preparation method of formulation is conventional method.
Any one in Prochloraz and lentinan, amino-oligosaccharide, Portugal's polyene sugar, harpin albumen is composite, two kinds of reactive compounds can be processed into any one formulation of permission, with specific embodiment, the preparation that two kinds of active ingredients are processed into is described below, but the preparation that these two kinds of active components can be processed be not limited only to following listed by.
Amino-oligosaccharide used in following examples, Portugal's polyene sugar, oligosaccharide, harpin albumen are commercially available prod, lentinan is according to Chen Xiaoguang, Wei rattan children, Peng Menghui etc., inner ebullition method extracts the process optimization of lentinan, [J]. Food Science, 2011,, medicinal extract prepared by 32 (10), the 31-34 methods optimized.Lentinan described in embodiment refers to the content of lentinan active ingredient in medicinal extract.Certainly, also the present invention is applicable to lentinan prepared by additive method.
The lentinan used in following examples is prepared by the following method:
Take 5g mushroom powder, be the ethanolic solution uniform wet 30min of 20% by 5mL volume fraction, make ethanolic solution fully permeate material; Add rapidly the water of 90 DEG C of 25ml, after extracting 30min, filter, the filtrate taken a morsel, measure Thick many candies content with phend-sulphuric acid.The volume concentration of the extract (i.e. filtrate) obtained respectively is to by 1.2 times of extract material, and then add 95% ethanol and make the ethanol content in concentrate be 75%, leave standstill, alcohol precipitation spends the night, and filter, 50 DEG C of vacuum dryings, obtain lentinan CE.The CE that takes a morsel analyzes polyoses content.Adopt phend-sulphuric acid to measure total sugar content, adopt 3.5-dinitrosalicylic Acid Colorimetry to measure content of reducing sugar, mushroom proteoglycan content %=(total sugar content-reduction total sugar content) × 0.9 × 100.Lentinan recovery rate is 5.05%, and in CE, polyoses content is 53.5%.
Embodiment 1
By Prochloraz 5g, lentinan 10g (active ingredient, down together), detergent LS (to methoxyl group fatty acid amido benzene sulfonic acid sodium salt) 2g, dispersing agent NNO (sodium methylene bis-naphthalene sulfonate) 4g, white carbon 5g, kaolin adds to 100g mixture and carries out air-flow crushing, and obtained principle active component weight percentage is 15% wetting powder.
Embodiment 2
By Prochloraz 10g, amino-oligosaccharide (Rushan Gold Mine, Shandong Han Wei bio tech ltd, 2g, detergent LS 3g, dispersing agent NNO 4g, white carbon 5g down together), kaolin adds to 100g mixture and carries out air-flow crushing, and obtained principle active component weight percentage is 50% wetting powder.
Embodiment 3
By Prochloraz 4g, Portugal's polyene sugar (Kai Linong bio tech ltd, Shandong, 0.2g, detergent LS 3g, dispersing agent NNO 4g, white carbon 5g down together), kaolin adds to 100g mixture and carries out air-flow crushing, and obtained principle active component weight percentage is 36% wetting powder.
Embodiment 4
Take 5g Prochloraz, harpin albumen (Eden Bioisystech Co., Ltd of the U.S., lower same) 0.1g, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, solvent naphtha 13g, adds water to 100g.The method above raw material being prepared routinely aqueous emulsion drops into the mixing of mixing kettle high speed, and making principle active component weight percentage is 55% Prochloraz-lentinan aqueous emulsion.
Embodiment 5
Take, 30g Prochloraz, 3g lentinan, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropyl alcohol 10g, adds water to 100g.The method above raw material being prepared routinely microemulsion drops in mixing kettle and mixes, and making principle active component weight percentage is 32% Prochloraz-lentinan microemulsion.
Embodiment 6
Take 26g Prochloraz, 5g amino-oligosaccharide, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, solvent naphtha 13g, adds water to 100g.The method above raw material being prepared routinely aqueous emulsion drops into the mixing of mixing kettle high speed, and making principle active component weight percentage is 55% Prochloraz-lentinan aqueous emulsion.
Embodiment 7
Take 50g Prochloraz, 0.5g Portugal polyene sugar, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, solvent naphtha 13g, adds water to 100g.The method above raw material being prepared routinely aqueous emulsion drops into the mixing of mixing kettle high speed, and making principle active component weight percentage is 55% Prochloraz-lentinan aqueous emulsion.
Embodiment 8
Take 20g Prochloraz, 0.2gharpin albumen, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulphate 4g thereof, xanthans 0.15g, ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, under the effect of sand mill, make principle active component weight percentage is 42% Prochloraz-lentinan suspending agent.
Embodiment 9
Take 15g Prochloraz, 1g amino-oligosaccharide, calcium dodecyl benzene sulfonate 6g, phenethyl phenol polyethenoxy ether phosphate 3g, agriculture breast 33#2g, alkylphenol polyoxyethylene 1g, isopropyl alcohol 10g, adds water to 100g.The method above raw material being prepared routinely microemulsion drops in mixing kettle and mixes, and making principle active component weight percentage is 32% Prochloraz-lentinan microemulsion.
Embodiment 10
Take 5g Prochloraz, 0.5g amino-oligosaccharide, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulphate 4g thereof, xanthans 0.15g, ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, under the effect of sand mill, make principle active component weight percentage is 42% Prochloraz-lentinan suspending agent.
Embodiment 11
Take 5g Prochloraz, 0.1 Portugal's polyene sugar, wooden sodium sulfonate 8g, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, diatomite 28g complements to 100g, and it is 7% Prochloraz-lentinan water dispersion granule that above raw material is made principle active component weight percentage by water dispersible granular agent method.
Embodiment 12
Take 10g Prochloraz, 0.1harpin albumen, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulphate 4g thereof, xanthans 0.15g, ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, under the effect of sand mill, make principle active component weight percentage is 42% Prochloraz-lentinan suspending agent.
Embodiment 13
Take 30g Prochloraz, 12g lentinan, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulphate 4g thereof, xanthans 0.15g, ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, under the effect of sand mill, make principle active component weight percentage is 42% Prochloraz-lentinan suspending agent.
Embodiment 13
Take 25g Prochloraz, 5g amino-oligosaccharide, wooden sodium sulfonate 8g, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, diatomite 28g complements to 100g, and it is 7% Prochloraz-lentinan water dispersion granule that above raw material is made principle active component weight percentage by water dispersible granular agent method.
Embodiment 14
Take 40g Prochloraz, 1g Portugal polyene sugar, wooden sodium sulfonate 8g, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, diatomite 28g complements to 100g, and it is 17% Prochloraz-lentinan water dispersion granule that above raw material is made principle active component weight percentage by water dispersible granular agent method.
Embodiment 15
Take 10g Prochloraz, 2g amino-oligosaccharide, lignin 2g, polyoxyethylene poly-oxygen propylene aether and sulphate 4g thereof, xanthans 0.15g, ethylene glycol 5g, silica ethane 0.10g, aluminium-magnesium silicate 0.5g, complement to 100g with water, under the effect of sand mill, make principle active component weight percentage is 20% Prochloraz-lentinan suspending agent.
Embodiment 16 indoor biometrics is tested
In indoor employing mycelial growth rate method, measure different agents to the EC of bacterial strain
50value, what adopt the abundant introduction of Sun Yun spends coefficient calculation method together, calculates the co-toxicity coefficient (CTC) of mixture, determines the building performance of mixture.
With single dose a certain in mixture for standard agent (selects EC usually
50junior), calculate:
Single dose toxicity index=standard agent EC
50/ certain single dose EC
50× 100
Toxicity index × B single dose proportion in mixture of toxicity index × A single dose proportion+B single dose in mixture of theoretical toxicity index=A single dose
The EC of actual measurement toxicity index=standard single dose
50the EC of value/mixture
50value × 100
Co-toxicity coefficient=actual measurement toxicity index/theoretical toxicity index × 100
When CTC is greater than 120, mixture has synergetic, and be antagonism when CTC is less than 80, CTC is summation action between 80-120.
According to the above method calculating co-toxicity coefficient, determine the synergetic of Prochloraz+lentinan, Prochloraz+amino-oligosaccharide, Prochloraz+Portugal's polyene sugar, Prochloraz+harpin albumen, result of the test is in Table 1-4:
Table 1: Prochloraz+lentinan different ratio (mass ratio) is to the indoor biometrics result of rice false smut (Ustilaginoideavirens (Cooke) Tak.)
| Medicament | Virulence regression equation | EC 50(mg/L) | Co-toxicity coefficient |
| 50% Prochloraz EC | Y＝1.8192X+2.1862 | 35.2168 | — |
| 0.8% lentinan AS | Y＝2.1015X+1.4265 | 50.1687 | — |
| Miaow: fragrant=(4:1) | Y＝1.7035X+2.5171 | 28.6761 | 152 |
| Miaow: fragrant=(2.5:1) | Y＝1.6116X+2.5392 | 33.6431 | 163 |
| Miaow: fragrant=(1:1) | Y＝1.3369X+2.8200 | 42.7201 | 138 |
As can be seen from Table 1, the microbicide compositions of Prochloraz and lentinan, have comparatively significantly synergetic to false smut, effect is better than the control efficiency of unitary agent.
Table 2: Prochloraz+amino-oligosaccharide different ratio is to the indoor biometrics result of cucumber anthracnose (Colletotrichum orbiculare Arx)
| Medicament | Virulence regression equation | EC 50(mg/L) | Co-toxicity coefficient |
| 50% Prochloraz EC | Y＝2.2643X+2.6248 | 11.1941 | — |
| 2% amino-oligosaccharide AS | Y＝2.3605X+1.5059 | 30.2164 | — |
| Miaow: ammonia=(8:1) | Y＝3.6935X+1.4482 | 9.1546 | 132 |
| Miaow: ammonia=(4:1) | Y＝3.0243X+2.1062 | 9.0546 | 142 |
| Miaow: ammonia=(2:1) | Y＝2.4511X+2.4514 | 10.9587 | 129 |
As can be seen from Table 2, the microbicide compositions of Prochloraz and amino-oligosaccharide, have comparatively significantly synergetic when preventing and treating anthracnose, effect is better than the control efficiency of unitary agent.
Table 3: Prochloraz+Portugal's polyene sugar different ratio is to botrytis cinerea (Botrytis cinerea Pers.) indoor biometrics result
| Medicament | Virulence regression equation | EC 50(mg/L) | Co-toxicity coefficient |
| 50% Prochloraz EC | Y＝1.6464X+2.5641 | 30.1684 | — |
| 0.5% Portugal polyene sugar SP | Y＝2.243X+4.8343 | 1.1854 | — |
| Miaow: Portugal=(10:1) | Y＝3.3614X+2.2571 | 6.5463 | 143 |
| Miaow: Portugal=(5:1) | Y＝3.8167X+2.6031 | 4.2461 | 140 |
| Miaow: Portugal=(3:1) | Y＝3.4674X+3.5033 | 2.7017 | 157 |
As can be seen from Table 3, the microbicide compositions of Prochloraz and Portugal's polyene sugar, have comparatively significantly synergetic to gray mold, effect is better than the control efficiency of unitary agent.
Table 4: Prochloraz+harpin albumen different ratio is to the indoor biometrics result of leaf spot of peanut bacterium (Cercospora personata)
| Medicament | Virulence regression equation | EC 50(mg/L) | Co-toxicity coefficient |
| 50% Prochloraz EC | Y＝1.2456X+3.3736 | 20.2168 | — |
| 1%harpin albumen fine granule | Y＝1.2817X+4.3449 | 3.2445 | — |
| Miaow: harpin=(6:1) | Y＝2.0573X+3.1239 | 8.1648 | 141 |
| Miaow: harpin=(4:1) | Y＝2.0935X+3.3613 | 6.0642 | 163 |
| Miaow: harpin=(2:1) | Y＝3.0762X+2.6847 | 5.6581 | 130 |
As can be seen from Table 4, the microbicide compositions of Prochloraz and lentinan, have comparatively significantly synergetic to leaf spot, effect is better than the control efficiency of unitary agent.
In summary it can be seen, any one in Prochloraz and lentinan, amino-oligosaccharide, Portugal's polyene sugar, harpin albumen is composite, and all show synergetic, therefore, this bactericide compounded composition has popularizing application prospect.Embodiment 17 field control effectiveness test:
1, test process: this test medicine consumption establishes three concentration for the treatment of respectively according to the difference of each composition, contrast medicament is the one of 50% Prochloraz EC and another selected bactericide and blank clean water experiment respectively.
2, each plot area of test method is 66.7m
2, repeat 3 times; Inspection drug effect method before dispenser after Investigation and Prevention is: random sampling 5 point in test treatment region, checks disease occurrence degree.
3, result of the test sees the following form 5-8:
Table 5: after medicine, 50 days 50% Prochloraz+lentinans are to the control efficiency (%) of rice green smut
Note: 20% Prochloraz lentinan EC in table 5 represents that the gross mass percentage composition of Prochloraz and lentinan is the EC of 20%.
Table 6: after medicine, 50 days 50% Prochloraz+amino-oligosaccharides are to the control efficiency (%) of cucumber anthracnose
Note: 20% Prochloraz amino-oligosacchride EC in table 6 represents that the gross mass percentage composition of Prochloraz and amino-oligosacchride is the EC of 20%.
Table 7: the 50 days 50% Prochloraz+control efficiency (%) of polyene sugar in Portugal's to graw mold of tomato after medicine
Note: 20% Prochloraz Portugal polyene sugar EC in table 7 represents that the gross mass percentage composition of Prochloraz and Portugal's polyene sugar is the EC of 20%.
Table 8: after medicine, 50 days 50% Prochloraz+harpin albumen is to the control efficiency (%) of leaf spot of peanut
Note: 20% Prochloraz Harpin albumen EC in table 8 represents that the gross mass percentage composition of Prochloraz and Harpin albumen is the EC of 20%.
Shown by indoor biometrics and field efficacy result, any one in Prochloraz and lentinan, amino-oligosaccharide, Portugal's polyene sugar, harpin albumen is composite has obvious synergistic function, the control efficiency of composition is excellent, control efficiency is all better than single dose kind, in agricultural application, there is using value, and have effect of increasing production after application process, crop has no adverse reaction.And can paddy growth be promoted after dispenser, the early ageing of control crop leaf, all has effect of increasing production, has application prospect.
Claims (10)
1. a bactericidal composition, is characterized in that wherein the first composition is Prochloraz, and the second composition is harpin albumen, and the weight ratio of the first composition and the second composition is 1 ~ 80:1 ~ 50 containing two kinds of active components.
2. bactericidal composition according to claim 1, is characterized in that the weight ratio of the first composition and the second composition is 5 ~ 50:1 ~ 50.
3. bactericidal composition according to claim 2, is characterized in that the weight ratio of the first described composition and the second composition is 1 ~ 10:1.
4. bactericidal composition according to claim 1, it is characterized in that gross weight percentage composition that both the first composition and the second composition account for composition be 2 ?80%.
5. bactericidal composition according to claim 4, it is characterized in that gross weight percentage composition that both the first composition and the second composition account for composition be 5 ?50%.
6. bactericidal composition according to claim 5, it is characterized in that gross weight percentage composition that both the first composition and the second composition account for composition be 8 ?40%.
7. bactericidal composition according to claim 1, is characterized in that described bactericidal composition with the first composition and the second composition for active ingredient and insecticides adjuvant, excipients are mixed with any one formulation that agricultural chemicals allows.
8. bactericidal composition according to claim 7, is characterized in that described formulation is missible oil, suspending agent, aqueous emulsion, wetting powder, microemulsion, water dispersion granule.
9. the application of bactericidal composition according to claim 1 in the medicine of preparation control fungal diseases of plants.
10. application according to claim 9, is characterized in that described plant is paddy, melon and fruit or vegetables; Described fungal disease is rice blast, false smut, bakanae disease of rice, rice sheath blight disease, anthracnose, leaf spot, stalk break, bacterial wilt, epidemic disease, penicilliosis, scab, fusarium wilt, wither here disease, damping off, root rot, tomato virus disease or gray mold.
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| CN103563958B (en) * | 2012-08-09 | 2015-06-03 | 南京华洲药业有限公司 | Bactericidal composition containing prochloraz and lentinan and application thereof |
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| CN105191997A (en) * | 2015-08-10 | 2015-12-30 | 谢绪叶 | A fungicide containing prochloraz and baicalin |
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| CN107006507A (en) * | 2017-05-31 | 2017-08-04 | 宾阳禾医生农业服务有限公司 | Sterilization synergistic composition containing Prochloraz |
| CN107306967A (en) * | 2017-07-10 | 2017-11-03 | 安徽丰乐农化有限责任公司 | A kind of bactericidal composition containing prothioconazoles and amino-oligosaccharide |
| CN107581001A (en) * | 2017-09-18 | 2018-01-16 | 南京林业大学 | A kind of crown prince method for planting ginseng of hilly region |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1849364A1 (en) * | 2006-04-26 | 2007-10-31 | Basf Aktiengesellschaft | Composition comprising a glucan or a glucan derivative and a pesticide and methods for improving plant health |
| ES2686540T3 (en) * | 2008-08-18 | 2018-10-18 | Mitsui Chemicals Agro, Inc. | Plant disease control agent comprising D-tagatose as an active ingredient and method for the control of plant diseases |
| CN101766220A (en) * | 2009-01-07 | 2010-07-07 | 黄峰 | Grapefruit preservative |
| CN101816305A (en) * | 2010-05-09 | 2010-09-01 | 海南正业中农高科股份有限公司 | Bactericide pesticide composite containing oligochitosan |
-
2012
- 2012-08-04 CN CN201510116776.4A patent/CN104757022A/en active Pending
- 2012-08-04 CN CN201210276968.8A patent/CN103563957B/en active Active
Non-Patent Citations (4)
| Title |
|---|
| 朱桂梅: "《新编农药应用表解手册》", 30 April 2011, 江苏科学技术出版社 * |
| 董玉: "《新一代杀菌剂——45%咪鲜•几丁糖水乳剂》", 《农药市场信息》 * |
| 邢来君，李明春，魏东盛: "《普通真菌学》", 30 June 2010, 高等教育出版社 * |
| 邱德文: "《蛋白质生物农药》", 31 May 2010, 科学出版社 * |
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| CN103563957A (en) | 2014-02-12 |
| CN103563957B (en) | 2015-09-30 |
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