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CN104707375A - Process system for preparing tenofovir disoproxil fumarate - Google Patents

Process system for preparing tenofovir disoproxil fumarate Download PDF

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Publication number
CN104707375A
CN104707375A CN201510135298.1A CN201510135298A CN104707375A CN 104707375 A CN104707375 A CN 104707375A CN 201510135298 A CN201510135298 A CN 201510135298A CN 104707375 A CN104707375 A CN 104707375A
Authority
CN
China
Prior art keywords
process system
tenofovir disoproxil
disoproxil fumarate
plakea
cone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510135298.1A
Other languages
Chinese (zh)
Inventor
邢将军
许刘华
曹铭
刘双喜
华俊国
刘明明
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sincere Pharmaceutcal Corp Ltd In Jiangsu
Original Assignee
Sincere Pharmaceutcal Corp Ltd In Jiangsu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sincere Pharmaceutcal Corp Ltd In Jiangsu filed Critical Sincere Pharmaceutcal Corp Ltd In Jiangsu
Priority to CN201510135298.1A priority Critical patent/CN104707375A/en
Publication of CN104707375A publication Critical patent/CN104707375A/en
Pending legal-status Critical Current

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  • Filtering Of Dispersed Particles In Gases (AREA)

Abstract

The invention provides a process system for preparing tenofovir disoproxil fumarate. The process system is characterized by comprising a filtering device (1), wherein the filtering device (1) comprises a dish-shaped body (2) and a pyramidal body (3), wherein an opening (4) is formed in one end of the dish-shaped body (2) and is matched with the inner side of an opening of the pyramidal body (3). The process system is low in cost, high in filtering efficiency, and suitable for pharmaceutical and chemical processes.

Description

One prepares tenofovir disoproxil fumarate process system
Technical field
The present invention relates to a kind of chemical reaction equipment, be specifically related to one and prepare tenofovir disoproxil fumarate process unit.
Background technology
Tenofovir disoproxil fumarate, its chemistry is by name: 9-((R)-2-((two (((isopropoxy carbonyl) oxygen base (methoxyl group) phosphinyl)-propyl group) adenine fumarate (1:1), be applicable to other antiretroviral drugs share, treatment HIV-1 infects.Preparing in tenofovir disoproxil fumarate process, relating to filtration link, because the coefficient of viscosity of different liquids is different, selecting different filters, increase cost.
Summary of the invention
In order to solve the problem, one is the object of the present invention is to provide to prepare tenofovir disoproxil fumarate multifunction craft device.
One provided by the invention prepares tenofovir disoproxil fumarate process unit technical scheme:
One prepares tenofovir disoproxil fumarate process system, comprises filter, and this filter comprises plakea, cone, and there is interface one end of described plakea, this interface and described pyramidal opening inner side suitable.
As preferably, described interface has screw thread, and described pyramidal opening inner side has suitable screw thread.
As preferably, described plakea has interlayer, this interlayer is provided with aperture, the interlayer of replaceable different small aperture on described plakea.
As preferably, described plakea can be suitable from the cone of different tapering.
Advantageous Effects of the present invention:
The present invention adopts split type filter, and plakea according to the viscosity of medium, can select the cone of suitable different taperings, and the interlayer of replaceable suitable small aperture, filters, both reduces cost, raise the efficiency simultaneously.
Accompanying drawing explanation
Fig. 1 is the outside schematic diagram of invention;
In Fig. 2, a1 is that interface has screw thread schematic diagram; B1 is that cone opening inner side has screw thread schematic diagram;
In Fig. 3, a2 is that interface is without screw thread schematic diagram; B2 is that cone opening inner side is without screw thread schematic diagram.
Detailed description of the invention
Below in conjunction with specific embodiment, set forth the present invention further.Should be understood that these embodiments are only not used in for illustration of the present invention to limit the scope of the invention.
Embodiment 1
As shown in Figure 1, 2, 3, one prepares tenofovir disoproxil fumarate process system, comprises filter 1, and this filter 1 comprises plakea 2, cone 3, there is interface 4 one end of described plakea 2, and this interface 4 is suitable with the opening inner side of described cone 3.
In the present embodiment, described interface 4 has screw thread, and the opening inner side of described cone 3 has suitable screw thread; And described plakea (2) has interlayer, this interlayer is provided with aperture, the interlayer of the upper replaceable different small aperture of described plakea (2).In filtering, described plakea 2 can be suitable from the cone 3 of different tapering.
The present invention adopts split type filter, and plakea according to the viscosity of medium, can select the cone of suitable different taperings, and the interlayer of replaceable suitable small aperture, filters, both reduces cost, raise the efficiency simultaneously.
Present specification describes some embodiments, but should be understood that those skilled in the art pass through to read this description and can know the various improvement not deviating from the spirit and scope of the present invention.Therefore, these other embodiments also should be included within the scope of appended claims.

Claims (4)

1. prepare tenofovir disoproxil fumarate process system for one kind, it is characterized by: comprise filter (1), this filter (1) comprises plakea (2), cone (3), there is interface (4) one end of described plakea (2), and this interface (4) is suitable with the opening inner side of described cone (3).
2. according to claim 1ly prepare tenofovir disoproxil fumarate process system, it is characterized by: described interface (4) has screw thread, the opening inner side of described cone (3) has suitable screw thread.
3. according to claim 1ly prepare tenofovir disoproxil fumarate process system, it is characterized by: (2) have interlayer to described plakea, and this interlayer is provided with aperture, the interlayer of the upper replaceable different small aperture of described plakea (2).
4. according to claim 1ly prepare tenofovir disoproxil fumarate process system, it is characterized by: described plakea (2) can be suitable from the cone of different tapering (3).
CN201510135298.1A 2015-03-26 2015-03-26 Process system for preparing tenofovir disoproxil fumarate Pending CN104707375A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510135298.1A CN104707375A (en) 2015-03-26 2015-03-26 Process system for preparing tenofovir disoproxil fumarate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510135298.1A CN104707375A (en) 2015-03-26 2015-03-26 Process system for preparing tenofovir disoproxil fumarate

Publications (1)

Publication Number Publication Date
CN104707375A true CN104707375A (en) 2015-06-17

Family

ID=53407407

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510135298.1A Pending CN104707375A (en) 2015-03-26 2015-03-26 Process system for preparing tenofovir disoproxil fumarate

Country Status (1)

Country Link
CN (1) CN104707375A (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1529635A (en) * 1975-04-28 1978-10-25 Cvi Corp Method and apparatus for filling vertically orientated filter beds with a particulate filter medium
CN2843577Y (en) * 2005-12-06 2006-12-06 南昌大学 Detachable vacuum pump filtering funnel
CN201776004U (en) * 2010-08-30 2011-03-30 江苏昊华精细化工有限公司 Detachable washable suction filtering funnel
CN203408527U (en) * 2013-07-09 2014-01-29 常州金土木工程仪器有限公司 Detachable type buchner funnel
CN204017481U (en) * 2014-09-01 2014-12-17 瑞阳制药有限公司 Vacuum filtration device easy to clean
CN204502513U (en) * 2015-03-26 2015-07-29 江苏诚信药业有限公司 One prepares tenofovir disoproxil fumarate process system

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1529635A (en) * 1975-04-28 1978-10-25 Cvi Corp Method and apparatus for filling vertically orientated filter beds with a particulate filter medium
CN2843577Y (en) * 2005-12-06 2006-12-06 南昌大学 Detachable vacuum pump filtering funnel
CN201776004U (en) * 2010-08-30 2011-03-30 江苏昊华精细化工有限公司 Detachable washable suction filtering funnel
CN203408527U (en) * 2013-07-09 2014-01-29 常州金土木工程仪器有限公司 Detachable type buchner funnel
CN204017481U (en) * 2014-09-01 2014-12-17 瑞阳制药有限公司 Vacuum filtration device easy to clean
CN204502513U (en) * 2015-03-26 2015-07-29 江苏诚信药业有限公司 One prepares tenofovir disoproxil fumarate process system

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20150617