CN104688562A - HD and ZPT composite anti-dandruff liquid shampoo and preparation method thereof - Google Patents
HD and ZPT composite anti-dandruff liquid shampoo and preparation method thereof Download PDFInfo
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- CN104688562A CN104688562A CN201410822885.3A CN201410822885A CN104688562A CN 104688562 A CN104688562 A CN 104688562A CN 201410822885 A CN201410822885 A CN 201410822885A CN 104688562 A CN104688562 A CN 104688562A
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- zpt
- dandruff
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- control shampoo
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- 239000002453 shampoo Substances 0.000 title claims abstract description 58
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 208000001840 Dandruff Diseases 0.000 title abstract description 28
- 239000002131 composite material Substances 0.000 title abstract description 6
- 239000007788 liquid Substances 0.000 title abstract 8
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 claims abstract description 58
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 51
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 31
- 239000004094 surface-active agent Substances 0.000 claims abstract description 29
- 235000005074 zinc chloride Nutrition 0.000 claims abstract description 29
- 239000011592 zinc chloride Substances 0.000 claims abstract description 29
- 239000011780 sodium chloride Substances 0.000 claims abstract description 28
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 24
- 150000005846 sugar alcohols Polymers 0.000 claims abstract description 23
- 239000008367 deionised water Substances 0.000 claims abstract description 22
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 17
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 229940075285 dandruff control Drugs 0.000 claims description 44
- 150000001875 compounds Chemical class 0.000 claims description 39
- 235000002639 sodium chloride Nutrition 0.000 claims description 33
- 150000001768 cations Chemical class 0.000 claims description 28
- 230000003571 opsonizing effect Effects 0.000 claims description 28
- 230000002421 anti-septic effect Effects 0.000 claims description 22
- 239000000080 wetting agent Substances 0.000 claims description 22
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 12
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 12
- PICXIOQBANWBIZ-UHFFFAOYSA-N zinc;1-oxidopyridine-2-thione Chemical compound [Zn+2].[O-]N1C=CC=CC1=S.[O-]N1C=CC=CC1=S PICXIOQBANWBIZ-UHFFFAOYSA-N 0.000 claims description 12
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 8
- 229920000570 polyether Polymers 0.000 claims description 8
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 claims description 8
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 claims description 6
- 229920002907 Guar gum Polymers 0.000 claims description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 6
- 238000005660 chlorination reaction Methods 0.000 claims description 6
- 238000001816 cooling Methods 0.000 claims description 6
- 238000007599 discharging Methods 0.000 claims description 6
- 239000000665 guar gum Substances 0.000 claims description 6
- 229960002154 guar gum Drugs 0.000 claims description 6
- 235000010417 guar gum Nutrition 0.000 claims description 6
- OQLKNTOKMBVBKV-UHFFFAOYSA-N hexamidine Chemical compound C1=CC(C(=N)N)=CC=C1OCCCCCCOC1=CC=C(C(N)=N)C=C1 OQLKNTOKMBVBKV-UHFFFAOYSA-N 0.000 claims description 6
- 229960001915 hexamidine Drugs 0.000 claims description 6
- SUMDYPCJJOFFON-UHFFFAOYSA-N isethionic acid Chemical compound OCCS(O)(=O)=O SUMDYPCJJOFFON-UHFFFAOYSA-N 0.000 claims description 6
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 claims description 6
- 150000003839 salts Chemical class 0.000 claims description 6
- 239000011734 sodium Substances 0.000 claims description 6
- 229910052708 sodium Inorganic materials 0.000 claims description 6
- 229940043810 zinc pyrithione Drugs 0.000 claims description 6
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 4
- 239000004721 Polyphenylene oxide Substances 0.000 claims description 4
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 4
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 4
- 239000002253 acid Substances 0.000 claims description 4
- BTBJBAZGXNKLQC-UHFFFAOYSA-N ammonium lauryl sulfate Chemical compound [NH4+].CCCCCCCCCCCCOS([O-])(=O)=O BTBJBAZGXNKLQC-UHFFFAOYSA-N 0.000 claims description 4
- 229940063953 ammonium lauryl sulfate Drugs 0.000 claims description 4
- 150000002148 esters Chemical class 0.000 claims description 4
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims description 4
- RRLOOYQHUHGIRJ-UHFFFAOYSA-M sodium;ethyl sulfate Chemical compound [Na+].CCOS([O-])(=O)=O RRLOOYQHUHGIRJ-UHFFFAOYSA-M 0.000 claims description 4
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical class CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 7
- 210000004209 hair Anatomy 0.000 abstract description 7
- 238000005516 engineering process Methods 0.000 abstract description 3
- 230000002045 lasting effect Effects 0.000 abstract description 2
- 206010052804 Drug tolerance Diseases 0.000 abstract 1
- 125000002091 cationic group Chemical group 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- 238000011010 flushing procedure Methods 0.000 abstract 1
- 239000003906 humectant Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 5
- 239000004327 boric acid Substances 0.000 description 5
- 230000007812 deficiency Effects 0.000 description 5
- 238000002791 soaking Methods 0.000 description 5
- 210000003128 head Anatomy 0.000 description 4
- 206010059866 Drug resistance Diseases 0.000 description 3
- 239000003599 detergent Substances 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 210000004761 scalp Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical group CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- 208000018380 Chemical injury Diseases 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 206010019049 Hair texture abnormal Diseases 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000000721 bacterilogical effect Effects 0.000 description 1
- 235000019437 butane-1,3-diol Nutrition 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 238000004020 luminiscence type Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 229940095673 shampoo product Drugs 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
The invention discloses HD and ZPT composite anti-dandruff liquid shampoo. The HD and ZPT composite anti-dandruff liquid shampoo is characterized by being prepared by mixing the following raw materials in percentage by weight: 0.3%-2.0% of a polyhydric alcohol humectant, 0.01-2.5% of sodium chloride, 10.0%-20.0% of a surfactant, 0.01%-0.5%of a cationic conditioner, 0.5%-2.6% of dimethiconol, 0.1%-0.2% of a preservative, 0.01%-0.1% of HD, 0.4%-1% of ZPT, 0.03%-0.1% of zinc chloride, 0.2%-0.6% of an essence and the balance of deionized water. The invention further discloses a preparation method of the HD and ZPT composite anti-dandruff liquid shampoo. The agency sense of water flushing of the liquid shampoo containing single ZPT is overcome; the defects of the anti-dandruff liquid shampoo containing single HD, such as high cost and the drug tolerance after long-time use are overcome; the HD and ZPT composite anti-dandruff liquid shampoo is low in cost and lasting in anti-dandruff effect; the hair is smooth and silky after the anti-dandruff liquid shampoo is used; the preparation technology is simple; the raw materials are safe and harmless; two anti-dandruff agents are reasonably combined; and the trouble of overmuch scurf is effectively solved.
Description
Technical field
The present invention relates to technical field of fine, be specifically related to compound dandruff control shampoo containing of a kind of HD and ZPT and preparation method thereof.
Background technology
The generation of the dandruff is that the horny layer face of constantly peeling off of epidermis produces, and is also metabolic result.The dandruff is many, and pore is blocked, just causes hair weak state, easy bacterial multiplication, and chafe produces head pruritus.Pathologic dandruff then refers to that scalp is because of bacteriological infection, fungal infection, or other physics, chemical injury cause scalp irritation.
Anion surfactant can remove fat secretion thing and the metabolism product at hair follicle place well, HD and ZPA has strong bactericidal action, dispels the dandruff, antipruritic completely, purification dandruff effect.Dandruff control shampoo containing is functional shampoo, is utilize some composition sterilization in product and clean, and without any dependency and side effect, can make daily shampoo life-time service.
Existing shampoo mostly is the single product of main component, and wherein, the shampoo product being main component with single ZPT, easily produces the deficiency relating to sense of bath when there is use; With the dandruff control shampoo containing that single HD is main component, then there is high cost and used of a specified duration the deficiency producing drug resistance.
Compound dandruff control shampoo containing is that common shampoo cannot be compared, and compound dandruff control shampoo containing thoroughly can effect a radical cure intractable dandruff for many years, builds healthy, value research very and inventing.But in the market, not yet occur better function, cost performance high, can the compound dandruff control shampoo containing of safe and efficient preparation.
Summary of the invention
For the above-mentioned deficiency of prior art, the object of the invention is to, the compound dandruff control shampoo containing of a kind of HD and ZPT and efficient, safe preparation method thereof are provided.What it had both overcome the bath that the shampoo containing single ZPT exists relates to sense, also overcome containing the dandruff control shampoo containing of single HD high cost and used to produce the deficiency of drug resistance of a specified duration.
The technical scheme that the present invention is adopted for achieving the above object is:
The compound dandruff control shampoo containing of a kind of HD and ZPT, is characterized in that: it is mixed with by weight percentage by following raw material components and forms:
Polyhydric alcohol wetting agent 0.3 ~ 2.0%;
Sodium chloride 0.01 ~ 2.5%;
Surfactant 10.0 ~ 20.0%;
Cation opsonizing agent 0.01 ~ 0.5%;
Dimethiconol 0.5 ~ 2.6%;
Antiseptic 0.01 ~ 0.2%;
HD 0.01～0.1%；
ZPT 0.4-1%；
Zinc chloride 0.03-0.1%;
Essence 0.2-0.6%;
Deionized water surplus.
Wherein, described polyhydric alcohol wetting agent is glycerol, propylene glycol or 1, more than one of 3 butanediols.Described sodium chloride is industrial chlorinations sodium or sea salt.Described surfactant be lauryl polyethers sodium sulfovinate, lauryl polyether thiourea acid esters ammonium, sodium lauryl sulfate, ammonium lauryl sulfate more than one.Described dimethiconol is the dimethiconol of 500,000 viscosity.Described HD is hexamidine two (hydroxyethylsulfonic acid .) salt; Described ZPT is the Zinc Pyrithione Zinc 2-pyridinethiol-1-oxide of 48% content.Described zinc chloride is analytical pure zinc chloride; Described cation opsonizing agent is C-14-S guar gum; Described antiseptic is Methylisothiazolinone.
A preparation method for the compound dandruff control shampoo containing of described HD and ZPT, is characterized in that: it comprises the steps:
1) component (preferably, before carrying out step 1), carrying out the pretreatment of equipment: after equipment and pipeline washed with de-ionized water are clean, the boric acid water soaking with 1% 30 minutes) of following mass percent is prepared:
Polyhydric alcohol wetting agent 0.3 ~ 2.0%;
Sodium chloride 0.01 ~ 2.5%;
Surfactant 10.0 ~ 20.0%;
Cation opsonizing agent 0.01 ~ 0.5%;
Dimethiconol 0.5 ~ 2.6%;
Antiseptic 0.01 ~ 0.2%;
HD 0.01～0.1%；
ZPT 0.4-1%；
Zinc chloride 0.03-0.1%;
Essence 0.2-0.6%;
Deionized water surplus;
2) being mixed with of the compound dandruff control shampoo containing of HD and ZPT:
First, by the deionized water in step 1), add in agitated kettle, start after adding cation opsonizing agent slowly to stir, start to heat after cation opsonizing agent fully disperses, temperature adds surfactant when arriving 75-78 DEG C and is stirred to surfactant and dimethiconol dissolves rear cooling completely, zinc chloride is added when 60 DEG C, then ZPT and HD is added, antiseptic, essence, polyhydric alcohol wetting agent is added when 45 DEG C, finally adjust viscosity to set point with sodium chloride, discharging after stirring, obtains the compound dandruff control shampoo containing of HD and ZPT.Wherein, the annual scope of described setting is 8000-10000mpa.s.
The invention has the advantages that: provide composite dandruff control shampoo containing of two kinds of anti-dandruff agent and preparation method thereof.Both overcome containing single ZPT that bath of shampoo relate to sense, also overcome containing the dandruff control shampoo containing of single HD high cost and used of a specified duration to produce the deficiency of drug resistance.HD and ZPT compound dandruff control shampoo containing cost is low, and anti-dandruff effect is lasting, sliding submissive with back luminescence.Its preparation technology is simple, and materials safety is harmless, reasonably two kinds of anti-dandruff agent is combined, the effectively firm worry of too much dandruff.
Detailed description of the invention
Embodiment 1
The compound dandruff control shampoo containing of a kind of HD and ZPT, it is mixed with by weight percentage by following raw material components and forms:
Polyhydric alcohol wetting agent 0.3 ~ 2.0%;
Sodium chloride 0.01 ~ 2.5%;
Surfactant 10.0 ~ 20.0%;
Cation opsonizing agent 0.01 ~ 0.5%;
Dimethiconol 0.5 ~ 2.6%;
Antiseptic 0.01 ~ 0.2%;
HD 0.01～0.1%；
ZPT 0.4-1%；
Zinc chloride 0.03-0.1%;
Essence 0.2-0.6%;
Deionized water surplus.
Wherein, described polyhydric alcohol wetting agent is glycerol, propylene glycol or 1, more than one of 3 butanediols.Described sodium chloride is industrial chlorinations sodium or sea salt.Described surfactant be lauryl polyethers sodium sulfovinate, lauryl polyether thiourea acid esters ammonium, sodium lauryl sulfate, ammonium lauryl sulfate more than one.Described dimethiconol is the dimethiconol of 500,000 viscosity.Described HD is hexamidine two (hydroxyethylsulfonic acid .) salt; Described ZPT is the Zinc Pyrithione Zinc 2-pyridinethiol-1-oxide of 48% content.Described zinc chloride is analytical pure zinc chloride; Described cation opsonizing agent is C-14-S guar gum; Described antiseptic is Methylisothiazolinone.
A preparation method for the compound dandruff control shampoo containing of described HD and ZPT, is characterized in that: it comprises the steps:
1) component (preferably, before carrying out step 1), carrying out the pretreatment of equipment: after equipment and pipeline washed with de-ionized water are clean, the boric acid water soaking with 1% 30 minutes) of following mass percent is prepared:
Polyhydric alcohol wetting agent 0.3 ~ 2.0%;
Sodium chloride 0.01 ~ 2.5%;
Surfactant 10.0 ~ 20.0%;
Cation opsonizing agent 0.01 ~ 0.5%;
Dimethiconol 0.5 ~ 2.6%;
Antiseptic 0.01 ~ 0.2%;
HD 0.01～0.1%；
ZPT 0.4-1%；
Zinc chloride 0.03-0.1%;
Essence 0.2-0.6%;
Deionized water surplus;
2) being mixed with of the compound dandruff control shampoo containing of HD and ZPT:
First, by the deionized water in step 1), add in agitated kettle, start after adding cation opsonizing agent slowly to stir, start to heat after cation opsonizing agent fully disperses, temperature adds surfactant when arriving 75-78 DEG C and is stirred to surfactant and dimethiconol dissolves rear cooling completely, zinc chloride is added when 60 DEG C, then ZPT and HD is added, antiseptic, essence, polyhydric alcohol wetting agent is added when 45 DEG C, finally adjust viscosity to set point with sodium chloride, discharging after stirring, obtains the compound dandruff control shampoo containing of HD and ZPT.Wherein, the annual scope of described setting is 8000-10000mpa.s.
Embodiment 2
The compound dandruff control shampoo containing of a kind of HD and ZPT, it is mixed with by weight percentage by following raw material components and forms:
Polyhydric alcohol wetting agent 0.3%;
Sodium chloride 0.01%;
Surfactant 10.0%;
Cation opsonizing agent 0.01%;
Dimethiconol 0.5%;
Antiseptic 0.01%;
HD 0.01%；
ZPT 0.4%；
Zinc chloride 0.03%;
Essence 0.2%;
Deionized water surplus.
Wherein, described polyhydric alcohol wetting agent is glycerol.Described sodium chloride is industrial chlorinations sodium or sea salt.Described surfactant (detergent) is lauryl polyethers sodium sulfovinate.Described dimethiconol is the dimethiconol of 500,000 viscosity.Described HD is hexamidine two (hydroxyethylsulfonic acid .) salt that BASF is produced.The Zinc Pyrithione Zinc 2-pyridinethiol-1-oxide of 48% content that described ZPT Shi Longsha company produces.Described zinc chloride is the analytical pure zinc chloride of western Gansu Province, Shantou Chemical Manufacture.Described essence CPL company produces.Described cation opsonizing agent is the sub-C-14-S guar gum in sieve ground.Described antiseptic is Methylisothiazolinone.
A preparation method for the compound dandruff control shampoo containing of described HD and ZPT, it comprises the steps:
1) component (preferably, before carrying out step 1), carrying out the pretreatment of equipment: after equipment and pipeline washed with de-ionized water are clean, the boric acid water soaking with 1% 30 minutes) of following mass percent is prepared:
Polyhydric alcohol wetting agent 0.3%;
Sodium chloride 0.01%;
Surfactant 10.0%;
Cation opsonizing agent 0.01%;
Dimethiconol 0.5%;
Antiseptic 0.01%;
HD 0.01%；
ZPT 0.4%；
Zinc chloride 0.03%;
Essence 0.2%;
Deionized water surplus;
2) being mixed with of the compound dandruff control shampoo containing of HD and ZPT:
First, by the deionized water in step 1), add in agitated kettle, start after adding cation opsonizing agent slowly to stir, start to heat after cation opsonizing agent fully disperses, temperature adds surfactant when arriving 75-78 DEG C and is stirred to surfactant and dimethiconol dissolves rear cooling completely, zinc chloride is added when 60 DEG C, then ZPT and HD is added, antiseptic, essence, polyhydric alcohol wetting agent is added when 45 DEG C, finally adjust viscosity to set point with sodium chloride, discharging after stirring, obtains the compound dandruff control shampoo containing of HD and ZPT.Wherein, the annual scope of described setting is 8000-10000mpa.s.
Embodiment 3
The compound dandruff control shampoo containing of a kind of HD and ZPT, it is mixed with by weight percentage by following raw material components and forms:
Polyhydric alcohol wetting agent 2.0%;
Sodium chloride 2.5%;
Surfactant 20.0%;
Cation opsonizing agent 0.5%;
Dimethiconol 2.6%;
Antiseptic 0.2%;
HD 0.1%；
ZPT 1%；
Zinc chloride 0.1%;
Essence 0.6%;
Deionized water surplus.
Wherein, described polyhydric alcohol wetting agent is propylene glycol.Described sodium chloride is industrial chlorinations sodium or sea salt.Described surfactant (detergent) is ammonium lauryl sulfate.Described dimethiconol is the dimethiconol of 500,000 viscosity.Described HD is hexamidine two (hydroxyethylsulfonic acid .) salt that BASF is produced.The Zinc Pyrithione Zinc 2-pyridinethiol-1-oxide of 48% content that described ZPT Shi Longsha company produces.Described zinc chloride is the analytical pure zinc chloride of western Gansu Province, Shantou Chemical Manufacture.Described essence CPL company produces.Described cation opsonizing agent is the sub-C-14-S guar gum in sieve ground.Described antiseptic is Methylisothiazolinone.
A preparation method for the compound dandruff control shampoo containing of described HD and ZPT, is characterized in that: it comprises the steps:
1) component (preferably, before carrying out step 1), carrying out the pretreatment of equipment: after equipment and pipeline washed with de-ionized water are clean, the boric acid water soaking with 1% 30 minutes) of following mass percent is prepared:
Polyhydric alcohol wetting agent 2.0%;
Sodium chloride 2.5%;
Surfactant 0.0%;
Cation opsonizing agent 0.5%;
Dimethiconol 2.6%;
Antiseptic 0.2%;
HD 0.1%；
ZPT 1%；
Zinc chloride 0.1%;
Essence 0.6%;
Deionized water surplus;
2) being mixed with of the compound dandruff control shampoo containing of HD and ZPT:
First, by the deionized water in step 1), add in agitated kettle, start after adding cation opsonizing agent slowly to stir, start to heat after cation opsonizing agent fully disperses, temperature adds surfactant when arriving 75-78 DEG C and is stirred to surfactant and dimethiconol dissolves rear cooling completely, zinc chloride is added when 60 DEG C, then ZPT and HD is added, antiseptic, essence, polyhydric alcohol wetting agent is added when 45 DEG C, finally adjust viscosity to set point with sodium chloride, discharging after stirring, obtains the compound dandruff control shampoo containing of HD and ZPT.Wherein, the annual scope of described setting is 8000-10000mpa.s.
Embodiment 4
The compound dandruff control shampoo containing of a kind of HD and ZPT, it is mixed with by weight percentage by following raw material components and forms:
Polyhydric alcohol wetting agent 1%;
Sodium chloride 1%;
Surfactant 15%;
Cation opsonizing agent 0.1%;
Dimethiconol 2%;
Antiseptic 0.1%;
HD 0.08%；
ZPT 0.5%；
Zinc chloride 0.05%;
Essence 0.4%;
Deionized water surplus.
Wherein, described polyhydric alcohol wetting agent is 1,3 butanediols.Described sodium chloride is industrial chlorinations sodium.Described surfactant is lauryl polyether thiourea acid esters ammonium, sodium lauryl sulfate mixture.Described dimethiconol is the dimethiconol of 500,000 viscosity.Described HD is hexamidine two (hydroxyethylsulfonic acid .) salt; Described ZPT is the Zinc Pyrithione Zinc 2-pyridinethiol-1-oxide of 48% content.Described zinc chloride is analytical pure zinc chloride; Described cation opsonizing agent is C-14-S guar gum; Described antiseptic is Methylisothiazolinone.
A preparation method for the compound dandruff control shampoo containing of described HD and ZPT, is characterized in that: it comprises the steps:
1) component (preferably, before carrying out step 1), carrying out the pretreatment of equipment: after equipment and pipeline washed with de-ionized water are clean, the boric acid water soaking with 1% 30 minutes) of following mass percent is prepared:
Polyhydric alcohol wetting agent 1%;
Sodium chloride 1%;
Surfactant 15%;
Cation opsonizing agent 0.1%;
Dimethiconol 2%;
Antiseptic 0.1%;
HD 0.08%；
ZPT 0.5%；
Zinc chloride 0.05%;
Essence 0.4%;
Deionized water surplus;
2) being mixed with of the compound dandruff control shampoo containing of HD and ZPT:
First, by the deionized water in step 1), add in agitated kettle, start after adding cation opsonizing agent slowly to stir, start to heat after cation opsonizing agent fully disperses, temperature adds surfactant when arriving 75-78 DEG C and is stirred to surfactant and dimethiconol dissolves rear cooling completely, zinc chloride is added when 60 DEG C, then ZPT and HD is added, antiseptic, essence, polyhydric alcohol wetting agent is added when 45 DEG C, finally adjust viscosity to set point with sodium chloride, discharging after stirring, obtains the compound dandruff control shampoo containing of HD and ZPT.Wherein, the annual scope of described setting is 8000-10000mpa.s.
Hair caring room test experiments:
Hair caring test utilizes China product H on the market to contrast for the M in reference product and embodiment.Experimenter is provided 0-10 by double blinding two products on probation to indices and divides, and 10 points represent that oneself is the most satisfied to this performance, and 0 point of representative is dissatisfied.Experimenter is the women of routine use hair care product.Specialty teacher adopt identical program very the time use H product on experimenter's half hair, second half hair used M product, then by identical amount and enough water rinse out.Application form, hair dryness finalization, is issued 18 professional teachers and 18 experimenters fill in corresponding project respectively by experimenter oneself.The experimenter participating in anti-dandruff effect assessment will fix half a head and use H sample, and another side uses M product, uses 14 days continuously.Every day carries out tracking evaluation marking by the dandruff situation of 18 professional teachers to every experimenter before using, and average is as the dandruff score value on the same day.Result gathers as follows:
| M | H | Difference | |
| Totally like degree | 7.05 | 6.50 | +0.55 |
| Top application type | 7.20 | 6.00 | +0.60 |
| Cardability (anti-entanglement) after dispersion | 8.0 | 6.45 | +1.55 |
| Slipping after top | 7.31 | 6.54 | +0.77 |
| The bath initial stage is smoothness | 7.20 | 6.67 | +0.53 |
| Bath is smoothness for mid-term | 7.22 | 6.50 | +0.72 |
| The bath later stage is smoothness | 7.00 | 6.45 | +0.55 |
| Bath later stage cardability (anti-entanglement) | 7.21 | 6.71 | +0.50 |
| A wet feel | 7.30 | 7.00 | +0.31 |
| Wet Comb rationality (anti-entanglement) | 6.95 | 6.6 | +0.35 |
| Antistatic | 6.23 | 6.18 | +0.05 |
| A dry feel | 7.58 | 7.03 | +0.5 |
| A dry elasticity | 6.11 | 6.25 | -0.14 |
The appreciable enhancing of positive difference representative energy, on antistatic property, difference is not obvious, and dry sending out in elasticity two performances is slightly worse than reference product H.
The experimenter participating in anti-dandruff effect assessment will fix half a head and use H sample, another side uses M product, continuous use 14 days, (10 are divided into dandruff little to carry out tracking evaluation marking by the dandruff situation of 18 professional teachers to every experimenter before using every day, 0 point of potential head bits especially severe), its average is as the dandruff score value on the same day.
| 1 day | 2 days | 3 days | 4 days | 5 days | 6 days | 7 days | 8 days | 9 days | 10 days | 11 days | 12 days | 13 days | 14 days | |
| M | 5 | 5.3 | 5.7 | 6.2 | 6.7 | 7.2 | 7.6 | 7.7 | 8.0 | 8.0 | 8.2 | 8.2 | 8.2 | 8.2 |
| H | 5 | 5.1 | 5.2 | 5.6 | 5.0 | 6.4 | 6.7 | 6.9 | 7.1 | 7.1 | 7.2 | 7.2 | 7.1 | 7.1 |
| Difference | 0.0 | 0.2 | 0.5 | 0.6 | 0.7 | 0.8 | 0.9 | 0.9 | 0.9 | 0.9 | 1.0 | 1.0 | 1.1 | 1.1 |
Embodiment M can be found in anti-dandruff to have clear superiority compared with market situation of selling well hit product H from above data.
The present invention is not limited to above-mentioned embodiment, the technical characteristic that all employings are identical or approximate with the above embodiment of the present invention, and compound dandruff control shampoo containing of other HD and ZPT obtained and preparation method thereof, all within protection scope of the present invention.
Claims (9)
1. the compound dandruff control shampoo containing of HD and ZPT, is characterized in that: it is mixed with by weight percentage by following raw material components and forms:
2. the compound dandruff control shampoo containing of HD and ZPT according to claim 1, is characterized in that: described polyhydric alcohol wetting agent is glycerol, propylene glycol or 1, more than one of 3 butanediols.
3. the compound dandruff control shampoo containing of HD and ZPT according to claim 1, is characterized in that: described sodium chloride is industrial chlorinations sodium or sea salt.
4. the compound dandruff control shampoo containing of HD and ZPT according to claim 1, is characterized in that: described surfactant be lauryl polyethers sodium sulfovinate, lauryl polyether thiourea acid esters ammonium, sodium lauryl sulfate, ammonium lauryl sulfate more than one.
5. the compound dandruff control shampoo containing of HD and ZPT according to claim 1, is characterized in that: described dimethiconol is the dimethiconol of 500,000 viscosity.
6. the compound dandruff control shampoo containing of HD and ZPT according to claim 1, is characterized in that: described HD is hexamidine two (hydroxyethylsulfonic acid .) salt; Described ZPT is the Zinc Pyrithione Zinc 2-pyridinethiol-1-oxide of 48% content.
7. the compound dandruff control shampoo containing of HD and ZPT according to claim 1, is characterized in that: described zinc chloride is analytical pure zinc chloride; Described cation opsonizing agent is C-14-S guar gum; Described antiseptic is Methylisothiazolinone.
8. a preparation method for the compound dandruff control shampoo containing of described HD and ZPT of one of claim 1-7, is characterized in that: it comprises the steps:
1) component of following mass percent is prepared:
2) being mixed with of the compound dandruff control shampoo containing of HD and ZPT:
First, by step 1) in deionized water, add in agitated kettle, start after adding cation opsonizing agent slowly to stir, start to heat after cation opsonizing agent fully disperses, temperature adds surfactant when arriving 75-78 DEG C and is stirred to surfactant and dimethiconol dissolves rear cooling completely, zinc chloride is added when 60 DEG C, then ZPT and HD is added, antiseptic, essence, polyhydric alcohol wetting agent is added when 45 DEG C, finally adjust viscosity to set point with sodium chloride, discharging after stirring, obtains the compound dandruff control shampoo containing of HD and ZPT.
9. the preparation method of the compound dandruff control shampoo containing of HD and ZPT according to claim 8, it is characterized in that, the annual scope of described setting is 8000-10000mpa.s.
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| CN107582447A (en) * | 2017-08-30 | 2018-01-16 | 曾万祥 | A kind of anti-dandruff ginger shampoo |
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