CN104623128A - Chinese medicinal preparation for treating myopia and preparation method thereof - Google Patents
Chinese medicinal preparation for treating myopia and preparation method thereof Download PDFInfo
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- CN104623128A CN104623128A CN201510018997.8A CN201510018997A CN104623128A CN 104623128 A CN104623128 A CN 104623128A CN 201510018997 A CN201510018997 A CN 201510018997A CN 104623128 A CN104623128 A CN 104623128A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 28
- 208000001491 myopia Diseases 0.000 title abstract description 22
- 230000004379 myopia Effects 0.000 title abstract description 18
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 11
- 235000012907 honey Nutrition 0.000 claims abstract description 4
- 239000000463 material Substances 0.000 claims abstract 2
- 241000628997 Flos Species 0.000 claims description 32
- 239000003814 drug Substances 0.000 claims description 27
- 241001649190 Campsis Species 0.000 claims description 8
- 239000010135 fructus aurantii immaturus Substances 0.000 claims description 8
- 241000411851 herbal medicine Species 0.000 claims 1
- 239000002994 raw material Substances 0.000 claims 1
- 229940126680 traditional chinese medicines Drugs 0.000 claims 1
- 210000005252 bulbus oculi Anatomy 0.000 abstract description 14
- 230000000694 effects Effects 0.000 abstract description 10
- 230000004438 eyesight Effects 0.000 abstract description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract description 6
- 208000003464 asthenopia Diseases 0.000 abstract description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 6
- 201000010099 disease Diseases 0.000 abstract description 5
- 230000000007 visual effect Effects 0.000 abstract description 5
- 239000000843 powder Substances 0.000 abstract description 4
- 239000000853 adhesive Substances 0.000 abstract description 3
- 230000001070 adhesive effect Effects 0.000 abstract description 3
- 238000000227 grinding Methods 0.000 abstract description 3
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract description 2
- 229940116229 borneol Drugs 0.000 abstract description 2
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract description 2
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract description 2
- 206010002556 Ankylosing Spondylitis Diseases 0.000 abstract 1
- 240000006248 Broussonetia kazinoki Species 0.000 abstract 1
- 241001113925 Buddleja Species 0.000 abstract 1
- 241001546929 Campsis grandiflora Species 0.000 abstract 1
- 208000001387 Causalgia Diseases 0.000 abstract 1
- 235000007516 Chrysanthemum Nutrition 0.000 abstract 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 abstract 1
- 244000183685 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 208000023890 Complex Regional Pain Syndromes Diseases 0.000 abstract 1
- 244000124209 Crocus sativus Species 0.000 abstract 1
- 235000015655 Crocus sativus Nutrition 0.000 abstract 1
- 235000010254 Jasminum officinale Nutrition 0.000 abstract 1
- 241000227425 Pieris rapae crucivora Species 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 240000003705 Senecio vulgaris Species 0.000 abstract 1
- 241000270708 Testudinidae Species 0.000 abstract 1
- 208000014439 complex regional pain syndrome type 2 Diseases 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 235000008216 herbs Nutrition 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 235000013974 saffron Nutrition 0.000 abstract 1
- 239000004248 saffron Substances 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
- 230000008961 swelling Effects 0.000 abstract 1
- 208000005494 xerophthalmia Diseases 0.000 abstract 1
- 210000001508 eye Anatomy 0.000 description 14
- 239000011505 plaster Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- 201000009310 astigmatism Diseases 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 231100000915 pathological change Toxicity 0.000 description 4
- 230000036285 pathological change Effects 0.000 description 4
- 208000017442 Retinal disease Diseases 0.000 description 3
- 206010038923 Retinopathy Diseases 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 230000002335 preservative effect Effects 0.000 description 3
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- SZGZILRQIYNODJ-UHFFFAOYSA-L disodium;7,12-dihydroquinoxalino[3,2-b]phenazine-2,9-disulfonate Chemical compound [Na+].[Na+].[O-]S(=O)(=O)C1=CC=C2N=C(C=C3C(NC4=CC=C(C=C4N3)S(=O)(=O)[O-])=C3)C3=NC2=C1 SZGZILRQIYNODJ-UHFFFAOYSA-L 0.000 description 2
- 230000004402 high myopia Effects 0.000 description 2
- 230000000774 hypoallergenic effect Effects 0.000 description 2
- 230000003204 osmotic effect Effects 0.000 description 2
- 239000004576 sand Substances 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 235000021419 vinegar Nutrition 0.000 description 2
- 239000000052 vinegar Substances 0.000 description 2
- 208000028048 Accommodation disease Diseases 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 201000010038 accommodative spasm Diseases 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 208000021024 autosomal recessive inheritance Diseases 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000001886 ciliary effect Effects 0.000 description 1
- 208000001309 degenerative myopia Diseases 0.000 description 1
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- 238000004519 manufacturing process Methods 0.000 description 1
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- 208000028261 multifactorial inheritance Diseases 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000004515 progressive myopia Effects 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000004355 spasm of accommodation Effects 0.000 description 1
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Abstract
The invention relates to a Chinese medicinal preparation for treating myopia and a preparation method thereof. The dressing for treating myopia and improving eyesight is prepared from natural honey, glycerol and the following 5000g of Chinese medicinal herbs by weight: 1,000g of chrysanthemum, 1,000g of prepared adhesive rehmannia rhizomes, 600g of tortoise shells, 500g of common white jasmine flowers, 500g of immature bitter oranges, 300g of pale butterflybush flowers, 300g of Chinese trumpetcreeper flowers, 300g of papermulberry fruits, 300g of borneol, 100g of saffron cocus styles and stigmas and 100g of all-grass of nakedcaule groundsel. The Chinese medicinal preparation is prepared by combining the 13 medicinal materials by precise weight ratio, drying, grinding into powder, sterilizing the powder at a high temperature, and protecting the powder against mould and decay. The Chinese medicinal preparation provided by the invention has the effects of treating eyeball diseases, fundus diseases, craniocerebral visual center diseases, xerophthalmia, eye strain and eyeball redness, swelling and causalgia. The clinical application of the Chinese medicinal preparation to over 100 patients shows that the Chinese medicinal preparation is superior to the existing commercially available Chinese medicinal products for treating ankylosing spondylitis in treatment effect, and the Chinese medicinal preparation is simple in formula, low in cost and good in treatment effect, is convenient to use and is superior to similar traditional products in effect.
Description
Technical field
The present invention relates to one and treat bathomorphic Chinese medicine preparation and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Eyeball development generally stopped before 18 ~ 20 years old, and myopia was high-speed development period at 12 ~ 18 years old, and just because teenager thirst for knowledge is strong during this, reading is many; Also because of the problem of educational system, homework is many, operation is hurried, and again because of the change of living habit, game mode, teenager outdoor activities is obviously reduced, is in for a long time and looks nearly state; More someone ignores eye hygiene, and this has just had opportunity to myopia.Distance and posture is not noted during reading, do not note the time of reading, light is insufficient, throw light on bright not or read and write and within several hours, do not have a rest continuously, causing excess eye-using, in this state, the long-term contracts last of ciliary muscle, first form the spasm of accommodation, asthenopia, further develop becomes myopia later.As to be less than 2 hours in this age bracket outside reading time, myope's number makes the words of benchmark, myope's number of 3 hours outside reading time is then its 2.1 times, within 4 ~ 5 hours, is then its 3.2 times, and visible excess eye-using forms bathomorphic main reason.Myopia has genetic predisposition, according to statistics, as with father and mother without bathomorphic myope's number for benchmark, one of father and mother have bathomorphic myope's number to be its 2.6 times, and father and mother have bathomorphic myope's number to be its 3.8 times.And in high myopic eye, genetic predisposition is more obvious.General myopia stopped development before 18 ~ 20 years old, but progressive myopia or some high myopia still likely developed after 20 years old.In hereditary myopia's eye, high myopia belongs to autosomal recessive inheritance, AR, and general myopia belongs to multifactorial inheritance disease.
Summary of the invention
Object of the present invention is just to provide a kind of by getting rid of eyeball pathological changes, and retinopathy, cranium brain visual centre pathological changes, eyeball are dry and astringent, the Chinese medicine preparation of eye strain, eyeball red and swollen heat pain and preparation method thereof (near-sighted improving eyesight subsides).
Chinese medicine preparation of the present invention and preparation method thereof, it is by Flos Chrysanthemi, Radix Rehmanniae Preparata, Carapax et Plastrum Testudinis, Flos jasmini, Fructus Aurantii Immaturus, Flos Buddlejae, Flos Campsis, Fructus Broussonetiae, Borneolum Syntheticum, Stigma Croci, Radix Semiaquilegiae, the Chinese medicines such as natural honey are made by following scheme, medicine each component consumption of the present invention is: Flos Chrysanthemi 800-1000 gram, Radix Rehmanniae Preparata 800-1000 gram, Carapax et Plastrum Testudinis 500-600 gram, Flos jasmini 400-500 gram, Fructus Aurantii Immaturus 400-500 gram, Flos Buddlejae 200-300 gram, Flos Campsis 200-300 gram, Fructus Broussonetiae 200-300 gram, Borneolum Syntheticum 200-300 gram, Stigma Croci 80-100 gram, Radix Semiaquilegiae 80-100 gram.(this is the proportioning of five kilograms of medicines).
Processing technology:
Myopia improving eyesight paste Making programme such as: manufacturing process all clean and bright ventilate indoor carry out.
1. getting sand puts in pot, after making popular with high heat, adds clean Carapax et Plastrum Testudinis, constantly stirs, and fries to surface faint yellow, takes out, and sieve removes sand, quench in vinegar, dry.Used time takes off broken.Roughly according to every Carapax et Plastrum Testudinis 100g, by the proportioning of vinegar 200g.
2. the medical materials such as Flos Chrysanthemi, Radix Rehmanniae Preparata, Flos jasmini, Fructus Aurantii Immaturus, Flos Buddlejae, Flos Campsis, Fructus Broussonetiae, Stigma Croci, Radix Semiaquilegiae are grabbed according to recipe ratio and prepare, dry in the sun 2-3 days.
3. under the environment of constant temperature 25-30 degree, repeatedly being pulverized by above-mentioned medicine pulverizer, is fine powdered to medicine, is smalls shape with grinding alms bowl by borneol and grinding.
4. by previous step except Borneolum Syntheticum medicated powder be in harmonious proportion to dough with Mel and glycerol in proportion, then adding Borneolum Syntheticum, to be fully mixed to medicine be slightly moistening dough.
5. above-mentioned dough medicine is divided into 1g every, and preserves with preservative film sealing, stored in plastic sealed container, the cold room sealing of putting into about 4 DEG C is preserved.
Detailed description of the invention
One of the present invention treats bathomorphic Chinese medicine preparation and preparation method thereof-" near-sighted improving eyesight subsides ", it be by: Flos Chrysanthemi, Radix Rehmanniae Preparata, Carapax et Plastrum Testudinis, Flos jasmini, Fructus Aurantii Immaturus, Flos Buddlejae, Flos Campsis, Fructus Broussonetiae, Borneolum Syntheticum, Stigma Croci, Radix Semiaquilegiae, natural honey are made by following scheme:
1. medicine each component consumption of the present invention is preferably:
Flos Chrysanthemi 1000 grams, Radix Rehmanniae Preparata 1000 grams, Carapax et Plastrum Testudinis 600 grams, Flos jasmini 500 grams, Fructus Aurantii Immaturus 500 grams, Flos Buddlejae 300 grams, Flos Campsis 300 grams, Fructus Broussonetiae 300 grams, Borneolum Syntheticum 300 grams, Stigma Croci 100 grams, Radix Semiaquilegiae 100 grams.(this is the proportioning of system 5 kilograms of medicines).
2. the method for medication:
1. patient is allowed fully to loosen, circumference of eyes skin carries out wiped clean, takes out above-mentioned 1g medicine, is kneaded open stoking across preservative film hands, and be divided into equivalent 14 parts, with hypo-allergenic adhesive plaster, medicine is affixed on the acupuncture point places such as patient's Jingming, Sibai, the sun, yang white, nebula wind.
2. enjoin patient to carry out far and near fixed point observation and look thing adjustment; Firmly opening eyes closes one's eyes sees word; The limit such as to be moved in an instant at the visual training, so that medicine energy rapid osmotic.
3. after terminating above-mentioned flow process, advise it to stay plaster to apply and after 6 hours, its plaster is taken off, usually reduce with eye, reduce the band mirror time.Treatment in three days once.
3. select the standard of case:
1. myopia (pseudomyopia, true myopia), astigmatism, stravismus.
2. eyeball dry and astringent, eye strain, eyeball red and swollen heat pain etc.
4. diagnostic criteria: there is the diagnosis of clinical myopia eye, eyes 5m naked vision, lower than 1.0, gets rid of eyeball pathological changes, the indications such as retinopathy, cranium brain visual centre pathological changes; Eyes have the patient such as astigmatism, stravismus; Eyeball is dry and astringent, tired, red and swollen heat pain etc. (getting rid of the pathogenic bacterial infections such as antibacterial).This product is secret prescription handed down in the family from generation to generation, and the combination of Gu Fa and modern method and innovation, all have obvious curative effects in addition.
5: therapeutic scheme:
1. patient is allowed fully to loosen, circumference of eyes skin carries out wiped clean, takes out above-mentioned 1g medicine, is kneaded open stoking across preservative film hands, and be divided into equivalent 14 parts, with hypo-allergenic adhesive plaster, medicine is affixed on the acupuncture point places such as patient's Jingming, Sibai, the sun, yang white, nebula wind.
2. enjoin patient to carry out far and near fixed point observation and look thing adjustment; Firmly opening eyes closes one's eyes sees word; The limit such as to be moved in an instant at the visual training, so that medicine energy rapid osmotic.
3. after terminating above-mentioned flow process, advise it to stay plaster to apply and after 6 hours, its plaster is taken off, usually reduce with eye, reduce the band mirror time.Treatment in three days once.
6. efficacy assessment standard:
Up to the present, that treats various disease with this medicine person-time reaches more than ten thousand people, total cure rate more than 95%, aggregate efficiency reaches 99%, but fail when also having some patients to go to a doctor to get rid of the objective irreversibility factors such as retinopathy, and some patients is against medical advice, excess eye-using, a large amount of spicy food of taking food, do not adhere to the cause influence cure rates such as partner treatment.
7. statistical procedures:
Select the treatment standard of case to suffering from myopia (pseudomyopia, true myopia), astigmatism, stravismus according to above-mentioned 3.Bathomorphic Chinese medicine preparation for the treatment of that eyeball is dry and astringent, 1083 people of eye strain, eyeball red and swollen heat pain etc. adopt the present invention to make and preparation method thereof-near-sighted improving eyesight is pasted, wherein male 378 people, female 705 people, the oldest person 35 years old, reckling 5 years old, average 18 years old; The most elder of the course of disease 15 years, the shortest person 190 days.2 courses for the treatment of add up as follows: cure 980 people, effective 95 people, invalid 8 people, total effective rate 99.38%, does not find that there is any toxic and side effects during medication, safe and reliable.
8. conclusion
100 routine clinical trial results displays, this kind of near-sighted improving eyesight is pasted treatment myopia (pseudomyopia, true myopia), astigmatism, stravismus.Eyeball is dry and astringent, the red and swollen heat of eye strain, eyeball etc. has significant curative effect, and its symptomes complice curative effect total effective rate is respectively 97.8%.This Chinese medicine preparation determined curative effect of Comprehensive Correlation, easy to use, and in application process, do not find obvious adverse reaction and have no side effect.
Claims (3)
1. bathomorphic Chinese medicine preparation for the treatment of and preparation method thereof, it is characterized in that: be made up of following traditional Chinese medicines material, tens Chinese herbal medicine such as Flos Chrysanthemi, Radix Rehmanniae Preparata, Carapax et Plastrum Testudinis, Flos jasmini, Fructus Aurantii Immaturus, Flos Buddlejae, Flos Campsis, Fructus Broussonetiae, Borneolum Syntheticum, Stigma Croci, Radix Semiaquilegiae, natural honey.
2. one according to claim 1 treats bathomorphic Chinese medicine preparation and preparation method thereof, it is characterized in that: make according to following weight proportion, Flos Chrysanthemi 800-1000 gram, Radix Rehmanniae Preparata 800-1000 gram, Carapax et Plastrum Testudinis 500-600 gram, Flos jasmini 400-500 gram, Fructus Aurantii Immaturus 400-500 gram, Flos Buddlejae 200-300 gram, Flos Campsis 200-300 gram, Fructus Broussonetiae 200-300 gram, Borneolum Syntheticum 200-300 gram, Stigma Croci 80-100 gram, Radix Semiaquilegiae 80-100 gram.(this is five kilograms of proportionings).
3. one according to claim 2 treats bathomorphic Chinese medicine preparation and preparation method thereof, it is characterized in that: each raw material preferred weight proportioning is made, Flos Chrysanthemi 1000 grams, Radix Rehmanniae Preparata 1000 grams, Carapax et Plastrum Testudinis 600 grams, Flos jasmini 500 grams, Fructus Aurantii Immaturus 500 grams, Flos Buddlejae 300 grams, Flos Campsis 300 grams, Fructus Broussonetiae 300 grams, Borneolum Syntheticum 300 grams, Stigma Croci 100 grams, Radix Semiaquilegiae 100 grams.(this is five kilograms of proportionings).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510018997.8A CN104623128A (en) | 2015-01-15 | 2015-01-15 | Chinese medicinal preparation for treating myopia and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510018997.8A CN104623128A (en) | 2015-01-15 | 2015-01-15 | Chinese medicinal preparation for treating myopia and preparation method thereof |
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| Publication Number | Publication Date |
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| CN104623128A true CN104623128A (en) | 2015-05-20 |
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Family Applications (1)
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| CN201510018997.8A Pending CN104623128A (en) | 2015-01-15 | 2015-01-15 | Chinese medicinal preparation for treating myopia and preparation method thereof |
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| Country | Link |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001302518A (en) * | 2000-02-15 | 2001-10-31 | Rohto Pharmaceut Co Ltd | Method for improving action and agent for improving action |
| CN1502347A (en) * | 2002-11-21 | 2004-06-09 | 浙江大学药业有限公司 | Xiguashuang eye medicine and preparation process thereof |
| CN103860731A (en) * | 2014-04-10 | 2014-06-18 | 源西峰 | Pure traditional Chinese medicine preparation for treating eye disease |
-
2015
- 2015-01-15 CN CN201510018997.8A patent/CN104623128A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001302518A (en) * | 2000-02-15 | 2001-10-31 | Rohto Pharmaceut Co Ltd | Method for improving action and agent for improving action |
| CN1502347A (en) * | 2002-11-21 | 2004-06-09 | 浙江大学药业有限公司 | Xiguashuang eye medicine and preparation process thereof |
| CN103860731A (en) * | 2014-04-10 | 2014-06-18 | 源西峰 | Pure traditional Chinese medicine preparation for treating eye disease |
Non-Patent Citations (1)
| Title |
|---|
| 石学敏: "《针灸治疗学》", 30 November 2002, 人民卫生出版社 * |
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Application publication date: 20150520 |
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