CN104606092A - A night toothpaste for calming the nerves and helping sleep and preparation method thereof - Google Patents
A night toothpaste for calming the nerves and helping sleep and preparation method thereof Download PDFInfo
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- 229940034610 toothpaste Drugs 0.000 title claims abstract description 24
- 239000000606 toothpaste Substances 0.000 title claims abstract description 24
- 230000001914 calming effect Effects 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 210000005036 nerve Anatomy 0.000 title claims description 13
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 30
- 235000008422 Schisandra chinensis Nutrition 0.000 claims abstract description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical group O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 229920001661 Chitosan Polymers 0.000 claims abstract description 16
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims abstract description 16
- 239000001768 carboxy methyl cellulose Substances 0.000 claims abstract description 16
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims abstract description 16
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims abstract description 16
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 15
- 239000008367 deionised water Substances 0.000 claims abstract description 15
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 15
- 239000003599 detergent Substances 0.000 claims abstract description 8
- 241001247821 Ziziphus Species 0.000 claims description 19
- 241000736075 Schisandra Species 0.000 claims description 15
- 239000006072 paste Substances 0.000 claims description 13
- 239000012459 cleaning agent Substances 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 7
- 238000011049 filling Methods 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 5
- 238000000227 grinding Methods 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims description 5
- 239000002994 raw material Substances 0.000 claims description 3
- ADWNFGORSPBALY-UHFFFAOYSA-M sodium;2-[dodecyl(methyl)amino]acetate Chemical compound [Na+].CCCCCCCCCCCCN(C)CC([O-])=O ADWNFGORSPBALY-UHFFFAOYSA-M 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 7
- 239000004615 ingredient Substances 0.000 abstract description 6
- 240000006079 Schisandra chinensis Species 0.000 abstract description 4
- 238000004140 cleaning Methods 0.000 abstract description 4
- 231100000957 no side effect Toxicity 0.000 abstract description 4
- 240000005005 Ziziphus jujuba var. spinosa Species 0.000 abstract 2
- FSYKKLYZXJSNPZ-UHFFFAOYSA-N sarcosine Chemical compound C[NH2+]CC([O-])=O FSYKKLYZXJSNPZ-UHFFFAOYSA-N 0.000 description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 108010077895 Sarcosine Proteins 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- SFNALCNOMXIBKG-UHFFFAOYSA-N ethylene glycol monododecyl ether Chemical compound CCCCCCCCCCCCOCCO SFNALCNOMXIBKG-UHFFFAOYSA-N 0.000 description 2
- 206010022437 insomnia Diseases 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
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- 239000011734 sodium Substances 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
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- 229920002101 Chitin Polymers 0.000 description 1
- 241000238424 Crustacea Species 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
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- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000191963 Staphylococcus epidermidis Species 0.000 description 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
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Abstract
本发明提出一种夜用安神助眠牙膏及其制备方法，按照质量百分比计算，其由如下组分制成:20％-35％的清洁剂，2％-5％的羧甲基纤维素钠，1％-3％的壳聚糖，10％-18％的酸枣仁提取液，5％-8％的五味子提取液，13％-20％的碳酸钙，余量为去离子水。本发明提出的夜用安神助眠牙膏，在现有牙膏配方的基础上增加了酸枣仁提取液、五味子提取液等安神静气成分，从而使得本发明既具有清洁牙齿之功效，同时又能有效帮助睡眠，安全有效，无副作用。The present invention provides a nighttime soothing and sleep-aiding toothpaste and a preparation method thereof. The toothpaste is made of the following components, calculated by mass percentage: 20%-35% of a detergent, 2%-5% of sodium carboxymethyl cellulose, 1%-3% of chitosan, 10%-18% of a spiny jujube seed extract, 5%-8% of a schisandra chinensis extract, 13%-20% of calcium carbonate, and the remainder is deionized water. The nighttime soothing and sleep-aiding toothpaste proposed by the present invention adds soothing and calming ingredients such as a spiny jujube seed extract and a schisandra chinensis extract to the existing toothpaste formula, so that the present invention has the effect of cleaning teeth and can effectively help sleep, is safe and effective, and has no side effects.
Description
技术领域technical field
本发明涉及日用化工清洗剂领域，特别涉及一种夜用安神助眠牙膏及其制备方法。The invention relates to the field of daily-use chemical cleaning agents, in particular to a night-use toothpaste for calming the nerves and helping sleep and a preparation method thereof.
背景技术Background technique
现有市场上的牙膏产品多种多样，归纳起来大致分为两种。一种是单纯洁齿护牙型的，另一种是含有药物可以为牙齿、牙龈进行口腔保健如消炎、止血、除异味等功效的。Toothpaste product on the existing market is varied, and sums up and roughly is divided into two kinds. One is a simple tooth cleaning type, and the other is a type that contains medicines that can perform oral health care for teeth and gums, such as anti-inflammatory, hemostasis, and deodorization.
失眠是一种常见的对人类健康及生活质量有危害的疾病。据统计，我国约有失眠患者1亿人左右，特别是在大中城市，患者比例较高。其会引起人的疲劳感、不安、全身不适、无精打采、反应迟钝、头痛、记忆力不集中，它的最大影响是精神方面，严重的甚至导致精神疾病。目前市场上尚未发现既能清洁牙齿，又能安神助眠的牙膏。Insomnia is a common disease that is harmful to human health and quality of life. According to statistics, there are about 100 million people with insomnia in my country, especially in large and medium cities, the proportion of patients is relatively high. It can cause fatigue, uneasiness, general malaise, listlessness, unresponsiveness, headache, and inability to concentrate. Its greatest impact is on the mental aspect, and it can even lead to mental illness in severe cases. There is no toothpaste that can not only clean teeth but also calm the nerves and help sleep in the market.
发明内容Contents of the invention
本发明为了弥补上述问题，提供一种夜用安神助眠牙膏及其制备方法，安神助眠效果好，且无副作用，制备方法绿色环保。In order to remedy the above problems, the present invention provides a toothpaste for soothing the nerves and helping sleep at night and a preparation method thereof, which has a good effect of soothing the nerves and helping sleep, has no side effects, and the preparation method is green and environment-friendly.
本发明提出的一种夜用安神助眠牙膏，按照质量百分比计算，其由如下组分制成:20％-35％的清洁剂，2％-5％的羧甲基纤维素钠，1％-3％的壳聚糖，10％-18％的酸枣仁提取液，5％-8％的五味子提取液，13％-20％的碳酸钙，余量为去离子水。A night-use toothpaste for calming the nerves and helping sleep proposed by the present invention, calculated according to mass percentage, is made of the following components: 20%-35% cleaning agent, 2%-5% sodium carboxymethylcellulose, 1% -3% chitosan, 10%-18% jujube seed extract, 5%-8% schisandra extract, 13%-20% calcium carbonate, and the balance is deionized water.
优选地，按照质量百分比计算，其由如下组分制成:25％的清洁剂，2％的羧甲基纤维素钠，3％的壳聚糖，16％的酸枣仁提取液，8％的五味子提取液，13％的碳酸钙，余量为去离子水。Preferably, calculated according to mass percentage, it is made of the following components: 25% detergent, 2% sodium carboxymethyl cellulose, 3% chitosan, 16% jujube seed extract, 8% Schisandra extract, 13% calcium carbonate, the balance is deionized water.
优选地，所述清洁剂为十二烷基硫酸钠、十二肌胺酸钠中任一种。Preferably, the cleaning agent is any one of sodium lauryl sulfate and sodium laureth sarcosine.
本发明还提出一种上述夜用安神助眠牙膏的制备方法，其包括如下步骤：The present invention also proposes a preparation method of the above-mentioned sleep-soothing toothpaste for night use, which comprises the following steps:
S00,按照比例制备原料；S00, prepare raw materials according to the ratio;
S10，将羧甲基纤维素钠放入去离子水中加热；S10, putting sodium carboxymethyl cellulose into deionized water and heating;
S20，往S10溶液中加入清洁剂、壳聚糖、酸枣仁提取液、五味子提取液，搅拌均匀，使之乳化完全；S20, add detergent, chitosan, jujube seed extract, and schisandra extract to the S10 solution, stir evenly, and emulsify completely;
S30，将步骤S20配置的溶液与碳酸钙粉混合，上三滚机研磨成细膏状；S30, mixing the solution configured in step S20 with calcium carbonate powder, and grinding it into a fine paste by the upper three rollers;
S40，用装膏机或人工装灌即为市售商品。S40 is a commercially available product that is filled with a paste filling machine or manually.
本发明提出的夜用安神助眠牙膏及其制备方法，在现有牙膏配方的基础上增加了酸枣仁提取液、五味子提取液等安神静气成分，从而使得本发明既具有清洁牙齿之功效，同时又能有效帮助睡眠，安全有效，无副作用；其方法安全、绿色、高效，易于产业化。The night-use toothpaste for calming the nerves and improving sleep and its preparation method proposed by the present invention, on the basis of the existing toothpaste formula, ingredients such as jujube seed extract, schisandra extract and other calming and calming ingredients are added, so that the present invention has the effect of cleaning teeth, At the same time, it can effectively help sleep, is safe and effective, and has no side effects; the method is safe, green, efficient, and easy to industrialize.
具体实施方式Detailed ways
应当理解，此处所描述的具体实施例仅仅用以解释本发明，并非用于限定本发明的范围。It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the scope of the present invention.
本发明提出的夜用安神助眠牙膏，按照质量百分比计算，其由如下组分制成:20％-35％的清洁剂，2％-5％的羧甲基纤维素钠，1％-3％的壳聚糖，10％-18％的酸枣仁提取液，5％-8％的五味子提取液，13％-20％的碳酸钙，余量为去离子水。The sleep-soothing toothpaste proposed by the present invention is calculated according to the mass percentage, and it is made of the following components: 20%-35% cleaning agent, 2%-5% sodium carboxymethylcellulose, 1%-3 % chitosan, 10%-18% jujube seed extract, 5%-8% schisandra extract, 13%-20% calcium carbonate, and the balance is deionized water.
优选地，按照质量百分比计算，其由如下组分制成:30％的清洁剂，4％的羧甲基纤维素钠，2％的壳聚糖，10％的酸枣仁提取液，5％的五味子提取液，15％的碳酸钙，余量为去离子水。Preferably, calculated according to mass percentage, it is made of the following components: 30% detergent, 4% sodium carboxymethyl cellulose, 2% chitosan, 10% jujube seed extract, 5% Schisandra extract, 15% calcium carbonate, the balance is deionized water.
优选地，按照质量百分比计算，其由如下组分制成:35％的清洁剂，5％的羧甲基纤维素钠，1％的壳聚糖，18％的酸枣仁提取液，6％的五味子提取液，20％的碳酸钙，余量为去离子水。Preferably, calculated according to mass percentage, it is made of the following components: 35% detergent, 5% sodium carboxymethyl cellulose, 1% chitosan, 18% jujube seed extract, 6% Schisandra extract, 20% calcium carbonate, and deionized water as the balance.
优选地，按照质量百分比计算，其由如下组分制成:25％的清洁剂，2％的羧甲基纤维素钠，3％的壳聚糖，16％的酸枣仁提取液，8％的五味子提取液，13％的碳酸钙，余量为去离子水。Preferably, calculated according to mass percentage, it is made of the following components: 25% detergent, 2% sodium carboxymethyl cellulose, 3% chitosan, 16% jujube seed extract, 8% Schisandra extract, 13% calcium carbonate, the balance is deionized water.
具体的，本实施例中，所述清洁剂为十二烷基硫酸钠，在其它实施方式中，所述清洁剂也可以为十二肌胺酸钠。其可以有效清洁牙齿上残留的食物残渣和污垢。Specifically, in this embodiment, the cleaning agent is sodium lauryl sulfate, and in other embodiments, the cleaning agent can also be sodium lauryl sarcosine. It can effectively clean the food residue and dirt left on the teeth.
所述羧甲基纤维素钠为粘结剂，使膏体均匀一致，表面平整光滑。The sodium carboxymethyl cellulose is used as a binding agent, so that the paste is uniform and the surface is flat and smooth.
所述壳聚糖是由甲壳动物的外壳及昆虫和其他无脊椎动物外壳提取的甲壳素经脱乙酰基后形成的。具有独特的生物活性，经水溶胀后形成弹性微粒，是一种优质摩擦材料，可取代现有牙膏中的如：二氧化硅、石粉、氢氧化铝等摩擦剂，避免牙膏对牙齿和口腔软组织的损伤。同时具有良好的杀菌、消炎作用，对金黄色葡萄球菌、表皮葡萄球菌、大肠杆菌、绿脓杆菌、白色念球菌等均有不同程度的抑制作用。The chitosan is formed by deacetylating chitin extracted from shells of crustaceans and shells of insects and other invertebrates. It has unique biological activity and forms elastic particles after being swollen with water. It is a high-quality friction material that can replace the friction agents in existing toothpaste such as silicon dioxide, stone powder, aluminum hydroxide, etc., and prevent toothpaste from damaging teeth and oral soft tissues. damage. At the same time, it has good bactericidal and anti-inflammatory effects, and has different degrees of inhibitory effects on Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans.
所述酸枣仁提取液是经酸枣仁粉碎，水煎提取而成，其中功效成分为枣仁皂甙，性平、味甘；能补肝、宁心、敛汗、生津。具有镇静催眠、降低心肌耗氧量、增加微循环、减少脑组织耗氧量、增强免疫力的作用。The jujube seed extract is obtained by pulverizing the jujube kernels and decocting them in water. The effective ingredient is jujube saponin, which is flat in nature and sweet in taste, and can nourish the liver, calm the heart, suppress sweat and promote body fluid. It has the effects of sedation and hypnosis, reducing myocardial oxygen consumption, increasing microcirculation, reducing brain tissue oxygen consumption, and enhancing immunity.
所述五味子提取液为药食两用的保健品，不仅有镇静安神的功效，还能益气强肝、增进细胞排除废物的效率、供应更多氧气、提高记忆力。The schisandra extract is a health product for both medicine and food. It not only has the effect of calming and calming the nerves, but also can nourish qi and strengthen the liver, improve the efficiency of cells to eliminate waste, supply more oxygen, and improve memory.
本发明还提出一种上述夜用安神助眠牙膏的制备方法，其其由如下组分制成:如下步骤：The present invention also proposes a preparation method of the above-mentioned toothpaste for soothing the nerves and helping sleep at night, which is made of the following components: following steps:
S00,按照比例制备原料；S00, prepare raw materials according to the ratio;
S10，将羧甲基纤维素钠放入去离子水中加热；S10, putting sodium carboxymethyl cellulose into deionized water and heating;
S20，往S10溶液中加入清洁剂、壳聚糖、酸枣仁提取液、五味子提取液，搅拌均匀，使之乳化完全；S20, add detergent, chitosan, jujube seed extract, and schisandra extract to the S10 solution, stir evenly, and emulsify completely;
S30，将步骤S20配置的溶液与碳酸钙粉混合，上三滚机研磨成细膏状；S30, mixing the solution configured in step S20 with calcium carbonate powder, and grinding it into a fine paste by the upper three rollers;
S40，用装膏机或人工装灌即为市售商品。S40 is a commercially available product that is filled with a paste filling machine or manually.
本发明提出的夜用安神助眠牙膏，在现有牙膏配方的基础上增加了酸枣仁提取液、五味子提取液等安神静气成分，从而使得本发明既具有清洁牙齿之功效，同时又能有效帮助睡眠。简单有效，无副作用。The night-use toothpaste for calming the nerves and helping sleep proposed by the present invention adds ingredients such as jujube seed extract, schisandra extract and other calming and calming ingredients on the basis of the existing toothpaste formula, so that the present invention not only has the effect of cleaning teeth, but also effectively Aids sleep. Simple and effective, no side effects.
实施例1Example 1
S10，将羧甲基纤维素钠50g放入300g去离子水中加热；S10, putting 50 g of sodium carboxymethyl cellulose into 300 g of deionized water and heating;
S20，往上述溶液中加入十二烷基硫酸钠200g、壳聚糖30g、酸枣仁提取液160g、五味子提取液80g，搅拌均匀，使之乳化完全；S20, add 200 g of sodium lauryl sulfate, 30 g of chitosan, 160 g of Jujube seed extract, and 80 g of Schisandra chinensis extract into the above solution, stir evenly, and make it emulsify completely;
S30，将步骤S20配置的溶液与碳酸钙粉130g混合，上三滚机研磨成细膏状；S30, mixing the solution configured in step S20 with 130 g of calcium carbonate powder, and grinding it into a fine paste by the upper three rollers;
S40，用装膏机或人工装灌即为市售商品。S40 is a commercially available product that is filled with a paste filling machine or manually.
实施例2Example 2
S10，将羧甲基纤维素钠20g放入490g去离子水中加热；S10, putting 20 g of sodium carboxymethyl cellulose into 490 g of deionized water and heating;
S20，往上述溶液中加入十二肌胺酸钠350g、壳聚糖10g、酸枣仁提取液180g、五味子提取液50g，搅拌均匀，使之乳化完全；S20, add 350 g of sodium laureth sarcosine, 10 g of chitosan, 180 g of jujube seed extract, and 50 g of schisandra extract to the above solution, stir evenly, and make it emulsify completely;
S30，将步骤S20配置的溶液与碳酸钙粉200g混合，上三滚机研磨成细膏状；S30, mixing the solution configured in step S20 with 200 g of calcium carbonate powder, and grinding it into a fine paste by the upper three rollers;
S40，用装膏机或人工装灌即为市售商品。S40 is a commercially available product that is filled with a paste filling machine or manually.
实施例3Example 3
S10，将羧甲基纤维素钠25g放入110g去离子水中加热；S10, putting 25 g of sodium carboxymethyl cellulose into 110 g of deionized water and heating;
S20，往上述溶液中加入十二烷基硫酸钠250g、壳聚糖15g、酸枣仁提取液100g、五味子提取液80g，搅拌均匀，使之乳化完全；S20, add 250g of sodium lauryl sulfate, 15g of chitosan, 100g of Jujube seed extract, 80g of Schisandra chinensis extract to the above solution, stir evenly, and make it emulsify completely;
S30，将步骤S20配置的溶液与碳酸钙粉180g混合，上三滚机研磨成细膏状；S30, the solution configured in step S20 is mixed with 180 g of calcium carbonate powder, and ground into a fine paste by the upper three rollers;
S40，用装膏机或人工装灌即为市售商品。S40 is a commercially available product that is filled with a paste filling machine or manually.
将上述实施例中的牙膏，对下列有不同症状的患者试用，每晚睡前使用，持续三周。结果如下：The toothpaste in the above-mentioned embodiment is tried out to the following patients with different symptoms, and it is used before going to bed every night for three weeks. The result is as follows:
由上述数据可知，本发明的夜用安神助眠型牙膏不仅洁齿、护齿，在针对睡眠不宁、难以入眠、烦躁易怒、心悸方面也有良好的改善效果。From the above data, it can be seen that the night-use sleep-soothing toothpaste of the present invention not only cleans teeth and protects teeth, but also has a good improvement effect on restless sleep, difficulty falling asleep, irritability, and heart palpitations.
以上所述仅为本发明的较佳实施例，并不用以限制本发明，凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。The above descriptions are only preferred embodiments of the present invention, and are not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included in the protection of the present invention. within range.
Claims (4)
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| CN106265249A (en) * | 2016-08-23 | 2017-01-04 | 黄云鸿 | A kind of environmental protection sleeping type toothpaste and preparation method |
| CN106344443A (en) * | 2016-08-24 | 2017-01-25 | 彭友莲 | Caring type toothpaste and preparation method thereof |
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