CN104586884A - Novel hemodialysis concentrate - Google Patents
Novel hemodialysis concentrate Download PDFInfo
- Publication number
- CN104586884A CN104586884A CN201510010508.4A CN201510010508A CN104586884A CN 104586884 A CN104586884 A CN 104586884A CN 201510010508 A CN201510010508 A CN 201510010508A CN 104586884 A CN104586884 A CN 104586884A
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- CN
- China
- Prior art keywords
- parts
- hemodialysis
- chloride
- concentrated solution
- concentrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000001631 haemodialysis Methods 0.000 title claims abstract description 23
- 230000000322 hemodialysis Effects 0.000 title claims abstract description 23
- 239000012141 concentrate Substances 0.000 title abstract 7
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims abstract description 16
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims abstract description 14
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims abstract description 14
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 14
- 238000007485 conventional hemodialysis Methods 0.000 claims abstract description 13
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 9
- 239000003792 electrolyte Substances 0.000 claims abstract description 9
- 239000008103 glucose Substances 0.000 claims abstract description 9
- 229910001629 magnesium chloride Inorganic materials 0.000 claims abstract description 8
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 229960000583 acetic acid Drugs 0.000 claims abstract description 7
- 239000012362 glacial acetic acid Substances 0.000 claims abstract description 7
- 239000001103 potassium chloride Substances 0.000 claims abstract description 7
- 235000011164 potassium chloride Nutrition 0.000 claims abstract description 7
- 239000011780 sodium chloride Substances 0.000 claims abstract description 7
- -1 23 parts Chemical compound 0.000 claims description 12
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 12
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 6
- 239000001110 calcium chloride Substances 0.000 claims description 6
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 6
- 235000017557 sodium bicarbonate Nutrition 0.000 claims description 6
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 6
- 238000000502 dialysis Methods 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 4
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 19
- 238000000034 method Methods 0.000 description 3
- 231100000643 Substance intoxication Toxicity 0.000 description 1
- 206010070863 Toxicity to various agents Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 208000020832 chronic kidney disease Diseases 0.000 description 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 description 1
- 239000000385 dialysis solution Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- CEIZFXOZIQNICU-UHFFFAOYSA-N tenuazonic acid Chemical compound CCC(C)C1NC(=O)C(C(C)=O)=C1O CEIZFXOZIQNICU-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a novel hemodialysis concentrate which is prepared from the following raw materials in parts by weight: 750-940 parts of medicinal sodium chloride, 26-30 parts of potassium chloride, 21-25 parts of magnesium chloride, 38-44 parts of magnesium chloride, 40-55 parts of glacial acetic acid, 450-540 parts of sodium bicarbonate, 120-200 parts of an electrolyte and 60-95 parts of glucose, wherein the raw materials are added into a conventional hemodialysis concentrate. The concentrate disclosed by the invention is mainly used for solving the phenomenon of 'hardening' in a production process of hemodialysis concentrate; and meanwhile, the storage property of the hemodialysis concentrate is enhanced, and the inconvenience of the medical personnel in preparing the hemodialysis concentrate is also solved. Moreover, the dialysis effect is better after the electrolyte and glucose are added.
Description
Technical field
The present invention relates to hemodialysis field, particularly relate to a kind of novel hemodialysis concentrated solution.
Background technology
Hemodialysis concentrated solution is the balance of maintaining dialysis patient ph balancing, ion, and vivotoxin is discharged in dialysis solution goes, hemodialysis concentrated solution common at present in process of production, easy generation " is hardened " phenomenon, greatly have impact on the effect of dialysis, and its shelf characteric is also poor, when the hemodialysis concentrated solution of Ei, bring very large inconvenience to medical personnel.
Summary of the invention
The present invention is exactly for the problems referred to above, proposes a kind of novel hemodialysis concentrated solution, and this concentrated solution effectively can not only solve " hardening " problem of producing and causing in hemodialysis concentrated solution process, and can make the better effects if of dialysis.
For reaching above-mentioned technical purpose, the novel hemodialysis concentrated solution that the present invention adopts, it is made up of the raw material of following ratio of weight and number: medicinal sodium chloride 750-940 part, potassium chloride 26-30 part, magnesium chloride 21-25 part, calcium chloride 38-44 part, glacial acetic acid 40-55 part, sodium bicarbonate 450-540 part electrolyte 120-200 part, glucose 60-95 part, joined in conventional hemodialysis (CHD) concentrated solution.
Dialysis concentrated solution of the present invention is applicable to acute, chronic renal failure and drug intoxication patient carries out hemodialysis, mainly solve " hardening " phenomenon caused in production hemodialysis concentration also process, adding the shelf characteric of hemodialysis concentrated solution simultaneously, also solving the inconvenience that medical personnel bring when configuring hemodialysis concentrated solution.And the better effects if of dialysis can be made after adding electrolyte and glucose.
Detailed description of the invention
Detailed description of the invention is adopted to be described in more detail the present invention below.
Embodiment 1
Novel hemodialysis concentrated solution, it is made up of the raw material of following ratio of weight and number: medicinal sodium chloride 750 parts, 26 parts, potassium chloride, 21 parts, magnesium chloride, 38 parts, calcium chloride, 40 parts, glacial acetic acid, sodium bicarbonate 450 parts of electrolyte 120 parts, glucose 60 parts, joined in conventional hemodialysis (CHD) concentrated solution.
Embodiment 2
Novel hemodialysis concentrated solution, it is made up of the raw material of following ratio of weight and number: medicinal sodium chloride 940 parts, 30 parts, potassium chloride, 25 parts, magnesium chloride, 44 parts, calcium chloride, 55 parts, glacial acetic acid, sodium bicarbonate 540 parts of electrolyte 200 parts, glucose 95 parts, joined in conventional hemodialysis (CHD) concentrated solution.
Embodiment 3
Novel hemodialysis concentrated solution, it is made up of the raw material of following ratio of weight and number: medicinal sodium chloride 900 parts, 28 parts, potassium chloride, 23 parts, magnesium chloride, 41 parts, calcium chloride, 42 parts, glacial acetic acid, sodium bicarbonate 510 parts of electrolyte 160 parts, glucose 80 parts, joined in conventional hemodialysis (CHD) concentrated solution.
Claims (2)
1. novel hemodialysis concentrated solution, it is characterized in that, it is made up of the raw material of following ratio of weight and number: medicinal sodium chloride 750-940 part, potassium chloride 26-30 part, magnesium chloride 21-25 part, calcium chloride 38-44 part, glacial acetic acid 40-55 part, sodium bicarbonate 450-540 part electrolyte 120-200 part, glucose 60-95 part, joined in conventional hemodialysis (CHD) concentrated solution.
2. novel hemodialysis concentrated solution as claimed in claim 1, it is characterized in that, it is made up of the raw material of following ratio of weight and number: medicinal sodium chloride 900 parts, 28 parts, potassium chloride, 23 parts, magnesium chloride, 41 parts, calcium chloride, 42 parts, glacial acetic acid, sodium bicarbonate 510 parts of electrolyte 160 parts, glucose 80 parts, joined in conventional hemodialysis (CHD) concentrated solution.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510010508.4A CN104586884A (en) | 2015-01-09 | 2015-01-09 | Novel hemodialysis concentrate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510010508.4A CN104586884A (en) | 2015-01-09 | 2015-01-09 | Novel hemodialysis concentrate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104586884A true CN104586884A (en) | 2015-05-06 |
Family
ID=53113156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510010508.4A Pending CN104586884A (en) | 2015-01-09 | 2015-01-09 | Novel hemodialysis concentrate |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104586884A (en) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1192961A2 (en) * | 2000-09-27 | 2002-04-03 | Nipro Corporation | Solid preparation for dialysis and process for producing the same |
| CN1744884A (en) * | 2003-01-31 | 2006-03-08 | 玛奈克股份有限公司 | Solid preparation for dialysis and process for producing the same |
| CN1919363A (en) * | 2006-09-15 | 2007-02-28 | 天津市肾友达医疗设备技术开发有限公司 | Novel dialytic concentrating preparation |
| CN101002795A (en) * | 2006-01-17 | 2007-07-25 | 彭罗民 | Method for preparing dialysis dry powder and dialysate of pure sodium bicarbonate |
| JP2009001594A (en) * | 2008-08-14 | 2009-01-08 | Nipro Corp | Solid preparation for dialysis and method for producing the same |
| CN101888846A (en) * | 2007-10-05 | 2010-11-17 | 国立大学法人千叶大学 | Stable drug solution containing bicarbonate ions |
| CN102370640A (en) * | 2010-08-18 | 2012-03-14 | 俞黎黎 | Compound amino acid preparation for hemodialysis and hemodialysis preparation containing same |
| CN103068397A (en) * | 2010-08-18 | 2013-04-24 | 弗雷森纽斯医疗护理德国有限责任公司 | Concentrate for medical solutions, production thereof and use thereof in dialysis |
| CN103720708A (en) * | 2012-10-10 | 2014-04-16 | 富田制药株式会社 | Dialysis agent a containing acetic acid and acetate salt, and a two-part dialysis agent using thereof |
-
2015
- 2015-01-09 CN CN201510010508.4A patent/CN104586884A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1192961A2 (en) * | 2000-09-27 | 2002-04-03 | Nipro Corporation | Solid preparation for dialysis and process for producing the same |
| CN1744884A (en) * | 2003-01-31 | 2006-03-08 | 玛奈克股份有限公司 | Solid preparation for dialysis and process for producing the same |
| CN101002795A (en) * | 2006-01-17 | 2007-07-25 | 彭罗民 | Method for preparing dialysis dry powder and dialysate of pure sodium bicarbonate |
| CN1919363A (en) * | 2006-09-15 | 2007-02-28 | 天津市肾友达医疗设备技术开发有限公司 | Novel dialytic concentrating preparation |
| CN101888846A (en) * | 2007-10-05 | 2010-11-17 | 国立大学法人千叶大学 | Stable drug solution containing bicarbonate ions |
| JP2009001594A (en) * | 2008-08-14 | 2009-01-08 | Nipro Corp | Solid preparation for dialysis and method for producing the same |
| CN102370640A (en) * | 2010-08-18 | 2012-03-14 | 俞黎黎 | Compound amino acid preparation for hemodialysis and hemodialysis preparation containing same |
| CN103068397A (en) * | 2010-08-18 | 2013-04-24 | 弗雷森纽斯医疗护理德国有限责任公司 | Concentrate for medical solutions, production thereof and use thereof in dialysis |
| CN103720708A (en) * | 2012-10-10 | 2014-04-16 | 富田制药株式会社 | Dialysis agent a containing acetic acid and acetate salt, and a two-part dialysis agent using thereof |
Non-Patent Citations (1)
| Title |
|---|
| 谭永红: "肾透析A、B液的配制与质量标准", 《西南国防医药》 * |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150506 |
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| RJ01 | Rejection of invention patent application after publication |