CN104586349B - Eye temperature measuring and analyzing system, receiving and analyzing device and method thereof - Google Patents

Abstract

A system for measuring and analyzing the temperature of an eye is used to measure, record and analyze the surface temperature of the eye. The system comprises an eye temperature measuring device and a receiving and analyzing device. The eye temperature measuring device comprises a temperature sensing component and a signal transmission component, and the data of the surface temperature of the eye measured by the temperature sensing component is transmitted to the outside through the signal transmission component. The receiving and analyzing device comprises a signal receiving unit and an analyzing unit, wherein the signal receiving unit receives the wireless signal, and the analyzing unit analyzes and judges whether the surface temperature of the eyes is normal or not according to the wireless signal.

Description

Eye temperature measuring and analyzing system, receiving and analyzing device and method thereof

technical field

The present invention relates to an eye temperature measurement and analysis system, receiving analysis device and method thereof, in particular to a system, analysis device and method for analyzing and judging eye surface temperature.

Background technique

The surface temperature of the eye reflects the state of the muscles or layers of the eyeball, so it can be used as an important indicator of eye health or disease. When the eyes are inflamed or when there is muscle tension (spasm), the ocular surface temperature will increase. For example, myopia caused by ciliary muscle spasm will increase the ocular surface temperature. However, in dry eye patients, between eyelid opening and closing, there is a decrease in ocular surface temperature due to reduced tear flow to the ocular surface. Therefore, an increase or decrease in ocular surface temperature can be used to judge whether the eye is healthy, approaching disease, or has developed disease.

D.M.Maurice and A.S.Mushin pointed out in the paper "Production of Myopia in Rabbits by Raised Body-Temperature and Increased Intraocular Pressure" (The Lancet; November 26, 1966, pp.1160-1162): when the body temperature of young rabbits rises to 41 At -43°C, after maintaining for about 30 minutes, the dioptres of the rabbit will reach above -0.75. The reason for myopia is that the refractive power of the eye is too large, so that the parallel rays parallel to the visual axis converge in front of the retina and cannot form a clear image on the retina. Furthermore, the change of the visual axis is also positively correlated with the temperature of the eyeball. Because the spasm of the ciliary muscle may stimulate the elongation of the visual axis of the eyeball, thereby forming irreversible true myopia, this paper also proves the correlation between eyeball temperature and myopia or eyeball changes. As the temperature of the eyeball rises, the sphere itself expands. In addition, the tissue around the eyeball has a strong resistance to expansion, so the expansion is transmitted to the bottom of the eyeball for development. Under this improper deformation of the eyeball, an eyeball with a longer visual axis is formed over time.

And Tien-Chun Chang, etc. wrote the paper "Application of digital infrared thermalimaging in determining inflammatory state and follow-up effect of methylprednisolone pulse therapy in patients with Graves'ophthalmopathy" (Graefes Arch Clin Exp Ophthalmol; 2008, 246 vol., pp. 45-49) pointed out that for Graves' disease (Graves'), the computerized far-infrared thermal imaging measures the local temperature, and can effectively assist in observing and recording the degree of inflammation of the eyeball. In addition, the paper "The application of temperature measurement of the eyes by digital infrared thermal imaging as a prognostic factor of methylprednisolone pulse therapy for Graves' ophthalmopathy" (ActaOphthalmologica; 2010 vol.88, pp.164-159) written by hyang-Rong Shih et al. It was learned that eye temperature decreases on average after high-dose steroid treatment, and the degree of temperature decrease is positively correlated with pre-treatment eye temperature. These studies have shown that temperature measurements from far-infrared thermography can help predict the response to high-dose steroid therapy for thyroid eye lesions.

In addition, due to the continuous miniaturization of electronic components for different purposes, there are more and more applications integrating such electronic components for wearable or embedded medical (or orthopedic) devices. For example, US Patent US2012/0245444 proposes a wearable contact lens combined with a biochip to detect the concentration of specific chemical substances in the precorneal (tear) film. Also US2010/0234717, US2013/0041245 and PCT international patent WO03/001991 proposed a contact lens combined with an electronic pressure sensor to measure the pressure in the eye. However, there are few patents or literatures proposing contact lenses combined with electronic temperature sensors to measure the surface temperature of the eyes, and there is even a lack of related prior patents that disclose the technical content of using contact lenses with temperature measurement functions to determine eye health or disease.

To sum up, eye medical treatment or vision correction urgently needs a system and method capable of judging eye health or disease, which can be widely used in preventive medicine and correction monitoring.

Contents of the invention

The object of the present invention is to provide a system for measuring and analyzing eye temperature, a receiving and analyzing device and a method thereof, which can analyze and judge whether the eye is healthy, close to a disease or has a disease by recording the data of the surface temperature of the eye, so it can For preventive medicine and orthopedic monitoring.

To achieve the above purpose, the present invention provides a system for measuring and analyzing eye temperature, comprising:

An eye temperature measuring device, placed on the surface of the eyeball, comprising:

a temperature sensing component that generates an electrical signal based on the surface temperature of the eye; and

a signal transmission component that converts the electrical signal into a wireless signal; and

A receiving analysis device, comprising:

a signal receiving unit for receiving the wireless signal; and

An analysis unit analyzes and judges whether the eye surface temperature is normal according to the wireless signal.

In the aforementioned eye temperature measurement and analysis system, the eye temperature measurement device further includes an antenna, and the antenna transmits the wireless signal to the outside.

As mentioned above, the eye temperature measurement and analysis system, wherein the antenna forms inductive coupling through external electromagnetic waves to generate power to supply the temperature sensing component and the signal transmission component. Wherein, it further includes an external antenna, and the external antenna transmits the wireless signal.

In the aforementioned eye temperature measurement and analysis system, the wireless signal is a signal that complies with radio frequency, bluetooth or WiFi.

The eye temperature measurement and analysis system as mentioned above, wherein the analysis unit is based on a temperature value of the eye surface, the difference between the temperature values at two time points, or the average value of the temperature values at multiple consecutive time points Or its changes to judge whether the eyes have lesions. Wherein, when the difference between nighttime temperature and daytime temperature of the surface temperature of the eye is lower than a lower limit, it is judged that the eye does not have myopia or pseudomyopia. Wherein, if the difference is between the lower limit and an upper limit, it is judged that the eyes may have myopia or pseudomyopia. Wherein, if the difference is greater than the upper limit, it is judged that the eyes have myopia or pseudomyopia.

As mentioned above, the eye temperature measurement and analysis system, wherein, when the temperature difference measured between the two time points of the eye is lower than a lower limit, it is judged that the eye should have dry eye syndrome. Wherein, the temperature values measured at the two time points are to measure the surface temperature of the eye immediately after blinking and opening the eyelid and to measure the surface temperature of the eye again between 6 and 10 seconds after the measurement, and the eyelid is between the two measurements. Continue to open. Wherein, when the temperature difference measured between the two time points of the eye is between 0.2° C. and 0.4° C., it is judged that the eye may have dry eye syndrome. Wherein, when the temperature difference measured between the two time points of the eye is greater than 0.4° C., it is judged that the probability of dry eye syndrome in the eye is low.

As mentioned above, the eye temperature measurement and analysis system, wherein the receiving and analyzing device is a computer, a tablet computer, a smart phone or a smart watch installed with specific software or application programs.

The measuring and analyzing system of eye temperature as mentioned above, wherein, this signal receiving unit comprises:

A mobile interrogation unit, which provides power required by the signal transmission component and the temperature sensing component, and receives the wireless signal to generate a radio frequency signal; and

A data receiving unit receives the radio frequency signal and converts it into data with eye surface temperature. Wherein, the analyzing unit is a computer.

As mentioned above, the eye temperature measurement and analysis system, wherein the temperature sensing component is a plurality of loop circuits, special application IC or micro-electro-mechanical component arranged on the surface of the contact lens.

The aforementioned eye temperature measurement and analysis system, wherein the eye temperature measurement device is a contact lens with a temperature measurement function.

The aforementioned eye temperature measurement and analysis system, wherein the eye temperature measurement device is placed on the surface of the eyeball and inside the eyelid to measure the temperature of the eye, and its size does not cover the pupil.

The present invention also provides an eye temperature receiving and analyzing device, comprising:

a signal receiving unit for receiving a wireless signal, wherein the wireless signal includes eye surface temperature data; and

An analysis unit analyzes and judges whether the eye surface temperature is normal according to the wireless signal.

The receiving and analyzing device for eye temperature as mentioned above, wherein the analysis unit is based on the temperature value of the eye surface, the difference between the temperature values at two time points, or the average value of the temperature values at multiple consecutive time points or its change To determine whether there is a lesion in the eye. Wherein, when the difference between nighttime temperature and daytime temperature of the surface temperature of the eye is lower than a lower limit, it is judged that the eye does not have myopia or pseudomyopia. Wherein, if the difference is between the lower limit and an upper limit, it is judged that the eyes may have myopia or pseudomyopia. Wherein, if the difference is greater than the upper limit, it is judged that the eyes have myopia or pseudomyopia.

As mentioned above, the eye temperature receiving and analyzing device, wherein, when the temperature difference measured between the two time points of the eye is lower than a lower limit, it is judged that the eye should have dry eye syndrome. Wherein, the temperature values measured at the two time points are to measure the eye surface temperature immediately after blinking and opening the eyelid and to measure the eye surface temperature again between 6 and 10 seconds after the measurement, and the eyelid is between the two measurements. Continue to open. Wherein, when the temperature difference measured between the two time points of the eye is between 0.2° C. and 0.4° C., it is judged that the eye may have dry eye syndrome. Wherein, when the temperature difference measured between the two time points of the eye is greater than 0.4° C., it is judged that the probability of dry eye syndrome in the eye is low.

The receiving analysis device of eye temperature as mentioned above, wherein, this signal receiving unit comprises:

a mobile interrogation unit receiving the wireless signal to generate a radio frequency signal; and

A data receiving unit receives the radio frequency signal and converts it into data with eye surface temperature. Wherein, the analysis unit is a computer.

The receiving and analyzing device for eye temperature as mentioned above, wherein the receiving and analyzing device is a computer, a tablet computer, a smart phone or a smart watch installed with specific software or application programs.

The invention provides a method for measuring and analyzing eye temperature, which comprises the following steps:

Measuring the surface temperature of the eye with an eye temperature measuring device placed on the surface of the eye;

transmitting the surface temperature data by wireless signal;

receive the radio signal; and

Analyzing and judging whether the surface temperature of the eye is normal according to the wireless signal.

The aforementioned method for measuring and analyzing eye temperature, wherein the wireless signal is a signal that meets the requirements of radio frequency, bluetooth or WiFi.

The method for measuring and analyzing eye temperature as mentioned above, wherein, the step of analyzing and judging further includes a temperature value of the eye, the difference between the temperature values at two time points, or the temperature values at multiple consecutive time points The average value or its change, in order to judge whether the eyes have lesions. Wherein, if the difference is lower than the lower limit, it is judged that the eyes should have or should not have lesions. Wherein, if the difference is between the lower limit value and an upper limit value, it is judged that there may be pathological changes in the eyes. Wherein, if the difference is greater than the upper limit, it is judged that the eyes should or should not have lesions.

Description of drawings

Fig. 1 is the broken line graph of daytime and night temperature difference of eye surface of pseudomyopia group and normal vision group in Table 1;

Fig. 2 is the schematic diagram of eye temperature measuring device of the present invention;

Fig. 3 is a schematic diagram of the eye temperature measuring device of Fig. 2 attached to the surface of the eye;

Fig. 4 is the schematic diagram of the measurement and analysis system of eye temperature of the present invention;

5 is a schematic diagram of another embodiment of the eye temperature measurement and analysis system of the present invention;

Fig. 6 is the flow chart of the measurement and analysis method of eye temperature of the present invention;

7 is a schematic diagram of another embodiment of the eye temperature measuring device of the present invention;

FIG. 8 is a schematic diagram of the eye temperature measuring device of FIG. 7 attached to the surface of the eye.

Description of main component symbols:

20 contact lenses

21 transparent substrate

22 Temperature Sensing Components

23 antennas

24 Signal transmission components

30 eyeballs

40 systems

41 Mobile Interrogation Unit

42 Data receiving unit

43 computer

411 Loop induction loop

50 systems

51 cell phone

52 desktop computers

61～64 steps

70 Eye temperature measuring device

71 Substrate

72 temperature sensing components

73 antennas

74 Signal transmission components

detailed description

For simplicity and clarity of illustration, the drawings illustrate the general manner of construction, and descriptions and details of well-known features and techniques may be omitted to avoid unnecessarily obscuring the present invention. Additionally, elements in the drawings are not necessarily drawn to scale. For example, the size of some of the elements in the figures may be exaggerated relative to other elements to help to improve understanding of embodiments of the invention. The same reference numerals in different drawings denote the same elements.

The terms "comprises," "comprising," and "having," and any variations thereof, in the description and claims are intended to cover a non-exclusive inclusion such that a program, method, system, object, means, or device that includes a series of elements does not necessarily is limited to those elements, but may include other elements not expressly listed or inherent to such a procedure, method, system, item, means, or apparatus.

As mentioned earlier, an increase or decrease in ocular surface temperature can be used to determine whether the eye is healthy, approaching disease, or has developed disease. Especially ciliary muscle spasm can cause myopia and make the ocular surface temperature rise. Table 1 below shows the measured eye surface temperature data of the pseudo-myopia group and the normal vision group.

Table I

Medical literature also pointed out that when the body temperature rises (high fever) or the surface temperature of the eyes will be caused by staring at something (books, TV, computer, mobile phone, etc.) It will cause the ciliary muscle to be in a state of high tension for a long time, and the temperature of the eyeball will increase due to the existence of such high tension. Although the ciliary muscle is overused for a long time during the day, when you sleep at night, the ciliary muscle will gradually relax, so the temperature should slowly drop. On the other hand, because the eyelids will be closed tightly during sleep, the release of heat to the outside is hindered, that is, the temperature of the eyeballs is still not easy or even impossible to drop. At the same time, when sleeping, the posture of the eyeball changes due to the change of body posture (such as lying down), which causes the pressure around the vitreous body of the eyeball to increase, and the high temperature and high pressure are transmitted from the inside to the bottom of the eyeball. Therefore, it is easy to cause the length of the eyeball in the direction of the visual axis to become longer. Because the same problem occurs again and again day after day, the visual axis length of the eyeball continues to lengthen, so that the image is formed in front of the retina, that is, myopia occurs.

Fig. 1 is a line graph of the temperature difference between daytime and nighttime of the eye surface of the pseudomyopia group and the normal vision group in Table 1. It can be clearly seen from the figure that the eye surface temperature of the pseudomyopic group has a large difference between nighttime and daytime temperatures, that is, the nighttime temperature of the eye surface is significantly higher. In contrast, the difference between the nighttime and daytime temperature of the eye surface of the normal vision group is smaller, that is, the nighttime temperature of the eye surface is slightly higher. Therefore, it is possible to analyze and judge whether the eye is healthy, close to a disease, or has a disease by recording the data of the eye surface temperature, so it can be used for preventive medicine and correction monitoring. The present invention is not limited to the judgment of myopia, dry eye or other eye symptoms showing temperature changes can also be applied to various embodiments of the present invention, or the conditions of various embodiments can be appropriately changed according to the magnitude and direction of temperature changes. Fig. 1 is the measurement of the eye surface temperature of two groups of people during the day and night, the present invention can also be used to measure the difference average of the eye surface temperature of the same person during the day and night for a long time, or measure the same person for a long time The maximum change or average value of the eye surface temperature at the same time point every day, or the difference and change of the eye surface temperature or the average temperature of a certain period of time. The foregoing embodiments do not limit the present invention, and the difference or average value of eye surface temperature over a long period of time or within a short period of time can be applied to the present invention.

As mentioned earlier, an increase or decrease in ocular surface temperature can be used to determine whether the eye is healthy, approaching disease, or has developed disease. In particular, dry eye syndrome can cause significant changes in ocular surface temperature due to insufficient tear secretion. Table 2 below shows the measured ocular surface temperature data of the dry eye patient group and the non-dry eye patient group.

Table II

To: Measure the eye surface temperature immediately by blinking and opening the eyelids.

Tc: Measure the eye surface temperature again 6 seconds after the To measurement (or select any time point between the 6th second and the 10th second), and the eyelids are kept open between the two measurements.

Td: is the difference between To and Tc.

It can be seen from the values in Table 2 that the difference Td of the dry eye group is significantly lower than that of the non-dry eye group. Therefore, this fact can be used as the basis for judging the occurrence of dry eye, and the judgment criteria can be listed as follows: when the difference Td is less than 0.2°C, it can be considered that the eyes should have dry eye; when the difference Td is between 0.2 When the temperature ranges from 0.4°C to 0.4°C, it can be considered that the eyes may have the risk of dry eye syndrome; when the difference is greater than 0.4°C, it can be considered that the probability of dry eye syndrome is low. The present invention is not limited by this embodiment, also can directly utilize the temperature value To or the single numerical value of Tc to determine another judgment criterion, or the variation (sudden increase, sudden decrease) of the curve formed by multiple temperature values To or Tc , increasing or decreasing) or slope changes set different judgment criteria. In fact, the content of the judgment criteria and the way of decision should be changed with different eye symptoms.

Fig. 2 is a schematic diagram of the eye temperature measuring device of the present invention. The eye temperature measuring device in this embodiment is a contact lens 20 with temperature measuring function, but the present invention is not limited thereto, and can be any wearing device placed on the surface of the eyeball to measure the temperature of the eye. The contact lens 20 mainly includes a transparent substrate 21 , a temperature sensing component (or temperature sensing circuit) 22 , an antenna 23 and a signal transmission component 24 . The material of the transparent substrate 21 can be silicone hydrogel (such as HEMA), which has the advantages of high oxygen permeability and hydrophilicity, so it can improve the wearer's comfort and is suitable for long-time wear. The material of the transparent substrate 21 can also be other transparent polymer materials, and is not limited by this embodiment. The antenna 23 can send wireless signals to the outside, and can also be used to receive external energy. For example, the antenna 23 can form an inductive coupling (inductive link or inductive coupling) effect through radio frequency signals or other electromagnetic waves, thereby generating electric energy supply and temperature sensing. The power required by the component 22 and the signal transmission component 24. In addition, the energy supply device that emits radio frequency signals or other electromagnetic waves can be placed in a scarf or placed in a pocket, or integrated into other portable devices (such as mobile phones, bluetooth earphones, etc.). However, this embodiment is not limited thereto, and a micro-electromechanical (MEMS) battery can also be disposed on the surface or inside of the transparent substrate 21 .

Due to the limited area of the contact lens 20 , the cycle number or size of the antenna 23 is also quite limited. In order to compensate that the signal strength of the antenna 23 may not be sufficient, an external antenna can be pasted around the eyes (such as the eye socket), so that the signal can be transmitted and strengthened, so that the signal receiver at a distance can clearly received.

In order to observe the temperature changes of the eyeball during the day and/or during sleep for a long time, on the surface of the transparent substrate 21 with the center of the contact lens 20 as the common center, several annular circuits capable of sensing temperature (i.e. the temperature sensing element 22) are coated. ), the circular line can be a plurality of circular circular lines, polygonal circular lines or irregular circular lines. The temperature sensing component 22 can be a special application IC (Application-Specific IC; ASIC) or a micro-electromechanical (MEMS) component, or a sensor formed with nanometer, pico (PECO) grade chemical materials, metal materials or biological materials. Measuring components that can be used to measure temperature or react to temperature changes. In addition, the signal transmission component 24 can convert the electrical signal (such as voltage signal or current signal) generated by the temperature sensing component 22 into a radio frequency (RF) signal, and transmit the wireless signal to the outside through the antenna 23 . However, the present invention is not limited to converting electrical signals into radio frequency (RF) signals, and may also be converted into signals of prescribed types such as Bluetooth or WiFi. Similar to the aforementioned loop lines, the antenna 23 is a plurality of loop lines coated on the surface of the transparent substrate 21 and surrounding the temperature sensing component 22, and can send wireless signals conforming to the communication protocol to the outside.

FIG. 3 is a schematic diagram of the eye temperature measuring device of FIG. 2 attached to the surface of the eye. As shown in the figure, when the subject puts the contact lens 20 on the surface of the eyeball 30, the temperature sensing element 22 and the antenna 23 with the ring circuit are located in the non-visual light-receiving area, so the light entering the pupil will not be blocked , not only can be worn during sleep at night, but also suitable for simultaneous measurement during daytime activities. This kind of contact lens 20 with temperature measurement function can be worn for a long time in normal life or work, and the subject does not need to be limited by the temperature measurement tool and can only stay in the measured area, for example: located in the prior art The front of the infrared thermometer used is convenient for activities, sleep or long-term measurement, thereby increasing the correctness of the judgment result.

Fig. 4 is a schematic diagram of the eye temperature measurement and analysis system of the present invention. The system 40 includes a contact lens 20 , a mobile interrogation unit 41 , a data receiving unit 42 and a computer 43 . The mobile interrogation unit 41 wirelessly provides the power required by the signal transmission component 24 and the temperature sensing component 22 through the loop induction loop 411, and receives a wireless signal including eye surface temperature data from the antenna 23 of the contact lens 20 , and demodulate the wireless signal to obtain the electrical signal, and then perform analog-to-digital conversion on the electrical signal to obtain a digital data related to the electrical signal, and then carry out modulation conversion on the digital data in a carrier to obtain a radio frequency signal. The data receiving unit 42 wirelessly receives the radio frequency signal from the mobile interrogation unit 41 and demodulates the radio frequency signal to obtain the digital data related to the electrical signal. The computer 43 stores a table corresponding to digital data and eye surface temperature, and is electrically connected to the data receiving unit 42 to receive the digital data, and looks up the table to obtain an eye surface temperature, which is displayed and stored.

The computer 43 can analyze and store the eye surface temperature data, and judge whether the eye surface temperature is normal. For example: the difference between the temperature of the eye surface at night and day (see Table 1) can be used to judge whether there is myopia or pseudomyopia; When the temperature is between 0.1°C and 0.3°C, it can be considered that the eyes may be myopic; when the difference is greater than 0.3°C, it can be considered that the eyes should be myopic. The result of the previous judgment can be displayed on the screen of the computer 43, or presented by the color of the indicator light of the data receiving unit 42, for example: green represents no doubt of myopia, yellow represents the possibility of myopia and red represents the occurrence of myopia. The present invention is not limited by the judgment criteria of the above embodiments, and may be determined according to the actual eye surface temperature and different symptoms.

This mobile inquiry unit 41, data receiving unit 42 and data analysis judgment (the present embodiment is responsible by computer 43) can be integrated into a reception analysis device, and this reception analysis device can be a computer that has installed specific software or application program , a tablet computer, a smart phone or a smart watch, the ring-shaped induction loop 411 can also be combined with or embedded in these devices.

Fig. 5 is a schematic diagram of another embodiment of the eye temperature measurement and analysis system of the present invention. System 50 is to use mobile phone 51 or desktop computer 52 as receiving and analyzing device, and this receiving and analyzing device comprises a signal receiving unit and an analyzing unit at least, and this signal receiving unit receives the wireless signal that contact lens 20 sends, and this analyzing unit will Analyzing and judging whether the eye surface temperature is normal according to the wireless signal.

Fig. 6 is a flow chart of the eye temperature measurement and analysis method of the present invention. The present invention provides a method for measuring and analyzing eye temperature, which comprises the following steps: as shown in step 61, measuring the surface temperature of the eye through a contact lens with a temperature measurement function; as shown in step 62, transmitting the temperature of the eye with a wireless signal Surface temperature data; as shown in step 63, accept the wireless signal; as shown in step 64, analyze and judge whether the surface temperature of the eye is normal according to the wireless signal.

Compared with the contact lens 20 in FIG. 3 , FIG. 7 is a schematic diagram of another embodiment of the eye temperature measuring device of the present invention. When the eye temperature measuring device 70 of this embodiment is worn on the surface of the eyeball, the pupil is not covered. In addition, the device of this embodiment can also be applied to the aforementioned eye temperature measurement and analysis system, that is, it can receive power supply from the mobile interrogation unit 41 and transmit wireless signals containing eye surface temperature data. The eye temperature measuring device 70 mainly includes a substrate 71 , a temperature sensing component (or temperature sensing circuit) 72 , an antenna 73 and a signal transmission component 74 . The material of the substrate 71 in this embodiment can be silicone hydrogel, polyester or polyacrylamide, and any material that allows light to fully penetrate, semi-transmit or not penetrate at all is suitable. The base material 71 can also be made of other polymer materials, soft or hard materials (for example: polysiloxane polymer, polymethyl methacrylate, need to match the shape of the eyeball arc), but it is not subject to this implementation. Example limitations. The antenna 73 can send wireless signals to the outside, and can also be used to receive external energy, for example: the antenna 73 forms an inductive coupling (inductive link or inductive coupling) effect through radio frequency signals or other electromagnetic waves, thereby generating electric energy to supply the temperature sensing component 72 And the power required by the signal transmission component 74. In addition, a micro battery can be arranged on the surface of the base material 71 , and the electric energy generated by it can directly supply the electric power required by the temperature sensing component 72 and the signal transmission component 74 .

Since the eye temperature measuring device 70 is placed inside the eyelid (see FIG. 8 ), its area may be limited, so the number of loops or the size of the antenna 73 is also limited. In order to compensate that the signal strength of the antenna 73 may not be sufficient, an external antenna can be pasted around the eyes (such as the eye socket), so that the signal can be transmitted and strengthened, so that the signal receiver at a distance can clearly received.

In order to observe the temperature change of the eyeball during the day and/or during sleep for a long time, several annular circuits (ie temperature sensing components 72) capable of sensing temperature are coated on the surface of the substrate 71, and the annular circuits can be a plurality of circles circular, polygonal, or irregular circular. The temperature sensing component 72 can be a special application IC (Application-Specific IC; ASIC) or a micro-electromechanical (MEMS) component, or a sensor formed with nanometer, pico (PECO) grade chemical materials, metal materials or biological materials. Measuring components that can be used to measure temperature or react to temperature changes. In addition, the signal transmitting component 74 can convert the electrical signal (such as a voltage signal or a current signal) generated by the temperature sensing component 72 into a radio frequency (RF) signal, and transmit the wireless signal to the outside through the antenna 73 . However, the present invention is not limited to converting electrical signals into radio frequency (RF) signals, and may also be converted into signals of prescribed types such as Bluetooth or WiFi. Similar to the aforementioned loop lines, the antenna 73 is a plurality of loop lines coated on the surface of the substrate 71 and surrounding the temperature sensing component 72, and can send wireless signals conforming to the communication protocol to the outside.

Fig. 8 is a schematic diagram of the eye temperature measuring device of the present invention attached to the surface of the eye. As shown in the figure, when the subject places the eye temperature measuring device 70 on the surface of the eyeball 30 and the inside of the eyelid (lower eyelid or upper eyelid), the base material 71 can be made of an opaque material because it is located in the non-visual light-receiving area, that is, no need Considering whether it will block the light entering the pupil, it can be worn not only when sleeping at night, but also suitable for simultaneous measurement during daytime activities. The shape of the substrate 71 can be half-moon or rectangular as shown in the figure, so as to be placed on the inside of the eyelid.

The technical content and technical features of the present invention have been disclosed above, but those skilled in the art may still make various replacements and modifications based on the teaching and disclosure of the present invention without departing from the spirit of the present invention. Therefore, the protection scope of the present invention should not be limited to those disclosed in the embodiments, but should include various replacements and modifications that do not depart from the present invention, and are covered by the claims.

Claims (29)

1. A measurement and analysis system for eye temperature, comprising: An eye temperature measuring device is placed on the surface of the eyeball, comprising: a temperature sensing component that generates an electrical signal based on the surface temperature of the eye; and a signal transmission component that converts the electrical signal into a wireless signal; and A receiving analysis device, comprising: a signal receiving unit for receiving the wireless signal; and An analyzing unit, analyzing and judging whether the eyes are normal according to the wireless signal, characterized in that, The analysis unit is based on a temperature value of the eye surface, the difference between the temperature values at two time points or the average value of the temperature values at multiple consecutive time points or the change of the temperature values at multiple consecutive time points to judge the eye Whether there are lesions. 2. The eye temperature measurement and analysis system according to claim 1, wherein the eye temperature measurement device further comprises an antenna, and the antenna transmits the wireless signal to the outside. 3 . The eye temperature measurement and analysis system according to claim 2 , wherein the antenna forms inductive coupling through external electromagnetic waves to generate power to supply the temperature sensing component and the signal transmission component. 4 . 4. The system for measuring and analyzing eye temperature as claimed in claim 2, further comprising an external antenna, which transmits the wireless signal. 5 . The eye temperature measurement and analysis system according to claim 1 , wherein the wireless signal is a signal compliant with radio frequency, bluetooth or WiFi. 6. The measurement and analysis system of eye temperature as claimed in claim 1, wherein when the difference between the nighttime temperature and the daytime temperature of the surface temperature of the eye is lower than a lower limit, it is judged that the eyes do not have myopia or pseudo-myopia. The occurrence of myopia. 7. The measurement and analysis system of eye temperature as claimed in claim 6, wherein the difference between the nighttime temperature and the daytime temperature of the surface temperature of the eye is between the lower limit value and an upper limit value, then It is judged that the eyes may have myopia or pseudomyopia. 8. The measurement and analysis system of eye temperature as claimed in claim 7, characterized in that, if the difference between nighttime temperature and daytime temperature of the surface temperature of the eye is greater than the upper limit, it is judged that the eye has myopia or pseudomyopia happened. 9. The measurement and analysis system of eye temperature as claimed in claim 1, characterized in that, when the temperature difference measured between the two time points of the eye is lower than a lower limit, it is judged that the eye should have dry eye syndrome . 10. The measurement and analysis system of eye temperature as claimed in claim 9, wherein the temperature values measured at the two time points are the eye surface temperature measured immediately after blinking and opening the eyelid and the 6th to 10th second after the measurement The eye surface temperature was measured again between the two measurements, and the eyelid was kept open between the two measurements. 11. The system for measuring and analyzing eye temperature as claimed in claim 10, wherein when the temperature difference measured between two time points of the eye is between 0.2°C and 0.4°C, it is judged that the eye may have occurrence of dry eye. 12. The system for measuring and analyzing eye temperature as claimed in claim 11, wherein when the difference between the temperature values measured between two time points of the eye is greater than 0.4°C, it is judged that the probability of dry eye syndrome in the eye is low. 13. The system for measuring and analyzing eye temperature according to claim 1, wherein the receiving and analyzing device is a computer, a smart phone or a smart watch installed with specific software or application programs. 14. The measurement and analysis system of eye temperature as claimed in claim 1, is characterized in that, this signal receiving unit comprises: A mobile interrogation unit, which provides power required by the signal transmission component and the temperature sensing component, and receives the wireless signal to generate a radio frequency signal; and A data receiving unit receives the radio frequency signal and converts it into data with eye surface temperature. 15. The eye temperature measurement and analysis system according to claim 14, wherein the analysis unit is a computer. 16. The eye temperature measurement and analysis system according to claim 1, wherein the temperature sensing component is a plurality of ring circuits, application-specific ICs, or micro-electromechanical devices arranged on the surface of the eye temperature measurement device. components. 17. The eye temperature measurement and analysis system according to claim 1, wherein the eye temperature measurement device is a contact lens with a temperature measurement function. 18. The eye temperature measurement and analysis system according to claim 1, wherein the eye temperature measurement device is placed on the surface of the eyeball and inside the eyelid to measure the temperature of the eye, and its size does not cover the pupil. 19. A device for receiving and analyzing eye temperature, comprising: a signal receiving unit for receiving a wireless signal, wherein the wireless signal is data including eye surface temperature; and An analyzing unit, analyzing and judging whether the eyes are normal according to the wireless signal, characterized in that, The analysis unit is based on the temperature value of the eye surface, the difference between the temperature values at two time points, or the average value of the temperature values at multiple consecutive time points, or the change in the temperature values at multiple consecutive time points to determine whether the eyes have occurrence of disease. 20. The device for receiving and analyzing eye temperature as claimed in claim 19, wherein when the difference between the nighttime temperature and the daytime temperature of the surface temperature of the eye is lower than a lower limit, it is judged that the eye does not have myopia or pseudomyopia happened. 21. The device for receiving and analyzing eye temperature as claimed in claim 20, characterized in that, if the difference between nighttime temperature and daytime temperature of the surface temperature of the eye is between the lower limit value and an upper limit value, then it is judged Eyes may have myopia or pseudomyopia. 22. The receiving and analyzing device of eye temperature as claimed in claim 21, characterized in that, if the difference between nighttime temperature and daytime temperature of the surface temperature of the eye is greater than the upper limit, it is judged that the eye has myopia or pseudomyopia occur. 23. The device for receiving and analyzing eye temperature as claimed in claim 19, wherein when the temperature difference measured between two time points of the eye is lower than a lower limit, it is judged that the eye should have dry eye syndrome. 24. The device for receiving and analyzing eye temperature as claimed in claim 23, characterized in that the temperature values measured at the two time points are measured immediately after blinking and opening the eyelids and between the 6th and 10th seconds after the measurement. The eye surface temperature was measured again between the two measurements, and the eyelid was kept open between the two measurements. 25. The device for receiving and analyzing eye temperature as claimed in claim 24, characterized in that, when the temperature difference measured between two time points of the eye is between 0.2°C and 0.4°C, it is judged that the eye may be dry. Occurrence of eye disease. 26. The device for receiving and analyzing eye temperature as claimed in claim 25, wherein when the difference of the temperature values measured between two time points of the eye is greater than 0.4°C, it is judged that the probability of dry eye syndrome in the eye is low. 27. The receiving analysis device of eye temperature as claimed in claim 19, is characterized in that, this signal receiving unit comprises: a mobile interrogation unit receiving the wireless signal to generate a radio frequency signal; and A data receiving unit receives the radio frequency signal and converts it into data with eye surface temperature. 28. The device for receiving and analyzing eye temperature according to claim 27, wherein the analysis unit is a computer. 29. The receiving and analyzing device for eye temperature as claimed in claim 19, wherein the receiving and analyzing device is a computer, a smart phone or a smart watch installed with specific software or application programs.