CN104546017A - Animal saliva collecting device - Google Patents

Abstract

The invention discloses an animal saliva collecting device, comprising an adsorption soft colloid, a saliva receiving cover, a saliva collecting device and an evacuating device, wherein one end of the adsorption soft colloid is fixed in the saliva receiving cover and the other end is a free end for an animal to chew; the saliva collecting device comprises a saliva collecting box, and a saliva inlet of the saliva collecting box is connected with the saliva receiving cover by a collecting pipe; the evacuating device comprises a vacuum suction pump which is connected with the saliva collecting box by a vacuum pipeline. By utilizing the animal saliva collecting device, a large amount of saliva can be collected without narcotizing animals and fixing animals by external force and without an operation.

Description

A device for collecting animal saliva

technical field

The invention relates to animal experiment equipment, in particular to an animal saliva collection device.

Background technique

Animal saliva not only contains various proteins, but also DNA, RNA, fatty acids, and various microorganisms. Various protein components in blood also exist in saliva, and saliva can reflect changes in the levels of various proteins in blood. Many diseases of animals can be diagnosed by saliva detection, such as dog rabies, swine fever, swine foot-and-mouth disease immune antibody detection; in addition, salivary gland bioreactor is a new type of bioreactor, the protein secreted by salivary glands is rich in saliva Therefore, it is necessary to collect saliva for detection and purification.

The secretion of saliva in animals is not limited by sex and developmental period. Animals secrete saliva throughout their life, and the amount of saliva secreted by large animals is large; in addition, salivary gland bioreactors are not limited by the type of protein expressed unlike blood bioreactors; Unlike mammary gland bioreactors, which cannot be collected until after childbirth, proteins in saliva are easy to separate and purify.

At present, the methods of saliva collection mainly contain the following: 1. The direct cotton ball collection method mainly puts cotton balls, cotton cloth or sponges, etc. Squeeze or centrifugal separation, this method is simple and easy to operate, without anesthesia, but the collection amount is small, and special personnel are required to collect, and it is difficult to cooperate with personnel to collect animals under passive conditions. 2. Intubation method. This method first anesthetizes the animal, injects pilocarpine, and then collects it through the opening of the salivary gland. It can collect more saliva without pollution, but each animal needs to be anesthetized and intubated, requiring more staff , The workload is heavy, and the collected saliva is not secreted under the normal conditions of the animals. 3. Negative pressure device collection method, the animal is anesthetized first, and then connected to a vacuum pump for collection. This method collects more saliva, but it is only suitable for small animals, requires anesthesia, and is not secreted under normal conditions. 4. Fistula operation method, which mainly separates the ducts of the parotid gland, submandibular gland, and sublingual gland through surgery, and then connects and collects them through the fistula. The saliva collected by this method is pollution-free and has a large amount of collection. It is a good collection method, but The operation is cumbersome and does some damage to the animals. The fistula cannot be kept in the body for a long time, and it is not suitable for collecting a large number of animals.

Contents of the invention

The object of the present invention is to overcome the deficiencies of the prior art, and provide an animal saliva collection device, which can collect a large amount of saliva without anesthesia, external fixation and surgery.

The technical scheme that the present invention solves the problems of the technologies described above is:

A device for collecting animal saliva, comprising a soft colloid for absorption, a saliva receiving cover, a saliva collecting device and a vacuum pumping device, wherein one end of the soft colloid for absorbing is fixed in the saliva receiving cover, and the other end is a free space for the animal to chew. end; the saliva collection device includes a saliva collection box, the liquid inlet of the saliva collection box is connected with the saliva receiving cover through a collection tube; the vacuum pump includes a vacuum pump, and the vacuum pump passes through a vacuum pipeline Connect with saliva collection box.

In a preferred solution of the present invention, an adsorption sponge is arranged inside the adsorption soft colloid, and capillary pores are densely covered on the surface. Its working principle is: part of the saliva flowing out of the animal is absorbed by the adsorption sponge through the capillary pores on the surface of the adsorption soft colloid, and directly flows into the collection tube under the action of vacuum suction, and enters the saliva collection device, and the other part flows out through the animal's mouth. The saliva is caught by the saliva receiving cover, then flows to the bottom and touches the soft colloid, and is sucked away by the vacuum suction force through the capillary pores on the surface of the soft colloid, and flows into the saliva collection device through the collection tube In addition, when the animal chews and absorbs the soft gel, it will squeeze the soft gel to a certain extent, which also helps the saliva to be sucked away.

Preferably, one end of the absorbent soft colloid that is connected to the saliva receiving cover is provided with a hollow hard plastic connecting section, and the upper end of the hard plastic connecting section is provided with external threads; the bottom of the saliva receiving cover is provided with a The connecting pipe extending downward, the upper end of the connecting pipe is provided with internal threads, the hard plastic connecting section extends into the connecting pipe and the two are screwed and fixed; the end of the collecting pipe is inserted into the hard plastic connecting pipe segments form connections. This structure not only facilitates the connection between the absorbent soft colloid and the saliva receiving cover, but also facilitates the connection between the collection tube and the absorbent soft colloid.

A preferred solution of the present invention, wherein the saliva receiving cover is made of stainless steel with a smooth surface, so that saliva flows easily and does not stick to the wall.

In a preferred solution of the present invention, wherein, the inner chamber of the saliva receiving cover has a gradually increasing structure from the bottom to the opening, which facilitates the flow and collection of saliva from the mouth to the bottom.

A preferred solution of the present invention, wherein, the middle part of the opening of the saliva receiving cover is sunken inward. Its purpose is to design according to the characteristics of the mouth shape of the animal. On the one hand, the lower jaw of the animal is pointed and blunt, and the saliva receiving cover with the above structure can easily catch and flow away the saliva flowing out from the tongue and lower jaw. This shape is easier to cover the entire lower jaw of the animal, and it is also similar to the feeding trough of the animal, which will not make the animal fearful.

In a preferred solution of the present invention, a fixing ring is provided on the saliva receiving cover, and the function of the fixing ring is to fix the saliva receiving cover on other objects, so that when the animal chews, it will not be affected by human factors.

A preferred solution of the present invention, wherein the liquid inlet of the saliva collection box is arranged on the top of the saliva collection box, and the top of the saliva collection box is also provided with a vacuum suction port, and the vacuum pipeline is connected to the vacuum suction port; The bottom of the saliva collection box is also provided with a liquid discharge port, and a valve is arranged in the liquid discharge port.

A preferred solution of the present invention further includes a filter device, the filter device includes a filter bottle body and a filter screen arranged in the filter bottle body, and the vacuum suction pump is connected to the top of the filter bottle body through a pipeline. The gas sucked by the vacuum suction pump can be filtered through the filter device.

A preferred solution of the present invention, wherein, the top of the filter bottle body is provided with a saliva inlet, and the bottom is provided with a saliva outlet, so that the filter device can be used to filter the saliva collected in the saliva collection box, so that the filter device can dual purpose.

The working principle of the animal saliva collection device of the present invention is: the soft colloid is non-toxic and not easy to be bitten, and has a certain elasticity. Under the action of the vacuum device, it is sucked into the saliva collection box for collection. In order to lure animals to chew the adsorption soft colloid, substances that can emit animal-liked odors can be provided in the adsorption soft colloid. In actual use, you can use another adsorption soft colloid with the same smell to lure the animal, put it near the animal's mouth or let it chew a few times, after it likes to chew the adsorption soft colloid, lure it to the saliva collection device, let it It chews the soft colloid that has been connected and fixed in the saliva collection device by itself.

Compared with the prior art, the present invention has the following beneficial effects:

1. Collect saliva by letting animals chew and absorb soft colloids by themselves, without anesthesia and external fixation of animals, and without surgery, eliminating the need for compulsory measures for animals. During the saliva collection process, the animals are in a natural state, and the collected saliva It can better reflect the physiological state of animals.

2. The operation is simple and flexible, the amount of saliva collected is large, and the applicability is wide, and the saliva of different animals can be collected.

Description of drawings

Fig. 1 is a structural schematic diagram of a specific embodiment of the animal saliva collection device of the present invention.

Fig. 2 is a schematic diagram of the structure of the adsorbed soft colloid in Fig. 1 .

Fig. 3 is a schematic structural view of the saliva receiving cover in Fig. 1 .

In the figure: 1. Adsorption soft colloid; 11. Hard plastic connecting section; 12. External thread; 2. Saliva receiving cover; 21. Fixed ring; 22. Internal thread; 23. Connecting tube; 3. Saliva collection device; 31 , liquid inlet; 32, vacuum suction port; 33, liquid discharge port; 34, saliva collection box; 4, vacuum suction pump; 5, filter device; 51, saliva import; , Filter the bottle body.

Detailed ways

The present invention will be further described in detail below in conjunction with the embodiments and the accompanying drawings, but the embodiments of the present invention are not limited thereto.

1 to 3, the animal saliva collection device of the present invention includes an adsorption soft colloid 1, a saliva receiving cover 2, a saliva collection device 3 and a vacuum device, wherein one end of the adsorption soft colloid 1 is fixed on the saliva receiving cover 2 Inside, the other end is a free end for allowing animals to chew; the saliva collection device 3 includes a saliva collection box, and the liquid inlet 31 of the saliva collection box is connected with the saliva receiving cover 2 through a collection tube; the vacuum pumping The device includes a vacuum suction pump 4, which is connected with the saliva collection box through a vacuum pipeline.

Referring to Figures 1 to 3, the adsorption soft colloid 1 is provided with an adsorption sponge 13 inside, and capillary pores 14 are densely covered on the surface. Its working principle is: part of the saliva flowing out from the animal is absorbed by the adsorption sponge 13 through the capillary pores 14 on the surface of the adsorption soft colloid 1, and directly flows into the collection tube under the action of vacuum suction, and then enters the saliva collection device 3, and the other part passes through The saliva flowing out of the animal's mouth is caught by the saliva receiving cover 2, and then flows to the bottom end to touch the adsorption soft colloid 1, and is sucked away by the capillary pores 14 on the surface of the adsorption soft colloid 1 under the action of vacuum suction, It flows into the saliva collection device 3 through the collecting tube; in addition, when the animal chews and absorbs the soft gel 1, it will squeeze the soft gel to a certain extent, which also helps the saliva to be sucked away.

Referring to Fig. 1～Fig. 3, one end connected with the saliva receiving cover 2 in the described adsorption soft colloid 1 is provided with the rigid plastic connection section 11 of hollow structure, and the upper end of this rigid plastic connection section 11 is provided with external thread 12; The bottom of the saliva receiving cover 2 is provided with a connecting pipe 23 extending downwards, and the upper end of the connecting pipe 23 is provided with an internal thread 22, and the hard plastic connecting section 11 extends into the connecting pipe 23 and both threads The connection is fixed; the end of the collection pipe is inserted into the hard plastic connection section 11 to form a connection. This structure not only facilitates the connection between the absorbent soft colloid 1 and the saliva receiving cover 2 , but also facilitates the connection between the collection tube and the absorbent soft colloid 1 .

Referring to Fig. 1 and Fig. 3, the saliva receiving cover 2 is made of stainless steel with a smooth surface so that saliva flows easily and does not stick to the wall. The inner cavity of the saliva receiving cover 2 has a gradually increasing structure from the bottom to the opening, which facilitates the flow and collection of saliva from the mouth to the bottom. The middle part of the opening of the saliva receiving cover 2 is sunken inwards, and its purpose is to design according to the mouth shape characteristics of the animal. The saliva is easy to catch and flow away. On the other hand, this shape is easier to cover the entire lower jaw of the animal, which is also similar to the feeding trough of the animal, and will not make the animal fearful.

Referring to Fig. 1 and Fig. 3, the saliva receiving cover 2 is provided with a fixing ring 21, and the function of the fixing ring 21 is to fix the saliva receiving cover 2 on other objects, so that when the animal chews, it will not be affected by human factors. The saliva receiving cover 2 can be fixed on objects of different heights according to the heights of different animals through the fixing ring 21 .

Referring to Fig. 1, the liquid inlet 31 of described saliva collection box is arranged on the top of saliva collection box, and the top of saliva collection box is also provided with vacuum suction port 32, and described vacuum pipeline is connected on this vacuum suction port 32; The bottom of the tank is also provided with a drain 33 in which a valve is provided.

Referring to Fig. 1, the animal saliva collection device of the present invention also comprises filter device 5, and this filter device 5 comprises filter bottle body and the filter screen 52 that is arranged in filter bottle body, and described vacuum suction pump 4 is connected in filter bottle body by pipeline. the top of. The gas sucked by the vacuum suction pump 4 can be filtered through the filter device 5 . The top of the filter bottle body is provided with a saliva inlet 51, and the bottom is provided with a saliva outlet 53, so that the filter device 5 can be used to filter the saliva collected in the saliva collection box, so that the filter device 5 can be used for two purposes.

1 to 3, the working principle of the animal saliva collection device of the present invention is: the adsorption soft colloid 1 is non-toxic and not easy to be bitten, and has certain elasticity. When the animal chews the adsorption soft colloid 1, the saliva produced The saliva is collected in the saliva receiving cover 2, and then sucked into the saliva collection box under the action of the vacuum device for collection. In order to lure animals to chew on the absorbent soft colloid 1 , substances that can emit the animal's favorite odor can be provided in the absorbent soft colloid 1 . In actual use, you can use another adsorption soft colloid 1 with the same smell to lure the animal, put it near the animal's mouth or let it chew a few times, and after it likes to chew the adsorption soft colloid 1, lure it to the saliva collection device , let it chew the soft colloid 1 that has been connected and fixed in the saliva collection device by itself.

The above is a preferred embodiment of the present invention, but the embodiment of the present invention is not limited by the above content, and any other changes, modifications, substitutions, combinations, and simplifications that do not deviate from the spirit and principles of the present invention are all Replacement methods that should be equivalent are all included within the protection scope of the present invention.

Claims (10)

1. A device for collecting animal saliva, characterized in that it comprises an adsorption soft colloid, a saliva receiving cover, a saliva collection device and a vacuum device, wherein one end of the adsorption soft colloid is fixed in the saliva receiving cover, and the other end is used At the free end for animals to chew; the saliva collection device includes a saliva collection box, and the liquid inlet of the saliva collection box is connected with the saliva receiving cover through a collection tube; the vacuum pumping device includes a vacuum suction pump, the vacuum The suction pump is connected with the saliva collection box through the vacuum pipeline. 2. The animal saliva collection device according to claim 1, characterized in that, the adsorption soft colloid is provided with an adsorption sponge inside, and the surface is densely covered with capillary pores. 3. The animal saliva collection device according to claim 2, characterized in that, the end connected with the saliva receiving cover in the adsorption soft colloid is provided with a hard plastic connection section of hollow structure, and the upper end of the hard plastic connection section An external thread is provided; the bottom of the saliva receiving cover is provided with a connecting pipe extending downward, and the upper end of the connecting pipe is provided with an internal thread, and the hard plastic connecting section extends into the connecting pipe and the two are threaded Fixed; the end of the collection tube is inserted into the hard plastic connecting section to form a connection. 4. The animal saliva collection device according to any one of claims 1-3, wherein the saliva receiving cover is made of stainless steel. 5. The animal saliva collection device according to any one of claims 1 to 3, characterized in that, the inner chamber of the saliva receiving cover has a gradually enlarged structure from the bottom to the opening. 6. The animal saliva collection device according to claim 5, characterized in that, the middle part of the opening of the saliva receiving cover is sunken inward. 7. The animal saliva collection device according to any one of claims 1-3, characterized in that a fixing ring is provided on the saliva receiving cover. 8. animal saliva collection device according to claim 1, is characterized in that, the liquid inlet of described saliva collection box is arranged on the top of saliva collection box, and the top of saliva collection box is also provided with vacuum suction port, and described vacuum pipeline It is connected to the vacuum suction port; the bottom of the saliva collection box is also provided with a drain port, and a valve is arranged in the drain port. 9. animal saliva collection device according to claim 1, is characterized in that, also comprises filter device, and this filter device comprises filter bottle body and the filter screen that is arranged in filter bottle body, and described vacuum suction pump is connected in the filter bottle body by pipeline. Filter the top of the bottle. 10. The animal saliva collection device according to claim 9, characterized in that, the top of the filter bottle is provided with a saliva inlet, and the bottom is provided with a saliva outlet.