CN104523449A - Anti-aging polypeptide compound and application thereof - Google Patents
Anti-aging polypeptide compound and application thereof Download PDFInfo
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- CN104523449A CN104523449A CN201510009992.9A CN201510009992A CN104523449A CN 104523449 A CN104523449 A CN 104523449A CN 201510009992 A CN201510009992 A CN 201510009992A CN 104523449 A CN104523449 A CN 104523449A
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- skin
- polypeptide compound
- defying age
- peptide complexes
- victory peptide
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- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 24
- 230000003712 anti-aging effect Effects 0.000 title abstract description 6
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract description 5
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 230000001815 facial effect Effects 0.000 claims abstract description 8
- 238000002360 preparation method Methods 0.000 claims abstract description 7
- IHRKJQSLKLYWBQ-QKDODKLFSA-N (2s)-2-[[(2s)-1-[(2s)-5-amino-2-[[2-(hexadecanoylamino)acetyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O IHRKJQSLKLYWBQ-QKDODKLFSA-N 0.000 abstract description 3
- 229940094946 palmitoyl tetrapeptide-7 Drugs 0.000 abstract description 3
- GFEYWOGCSROPRT-OBXVVNIGSA-N (2s)-1-[(2s)-2-[[(2s)-1-[(2s)-2-[[(2s)-2-[[(2s)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid Chemical compound C([C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N1[C@@H](CCC1)C(O)=O)C1=CC=CC=C1 GFEYWOGCSROPRT-OBXVVNIGSA-N 0.000 abstract 1
- LODWEXDBRZBADB-XEVVZDEMSA-N (2s)-6-amino-2-[[(2s)-2-[[(2s)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-methylbutanoyl]amino]hexanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(O)=O LODWEXDBRZBADB-XEVVZDEMSA-N 0.000 abstract 1
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- HSUGRPOJOBRRBK-SXBSVMRRSA-N acetic acid;(2s)-n-[(2s)-4-amino-1-(benzylamino)-1-oxobutan-2-yl]-1-(3-aminopropanoyl)pyrrolidine-2-carboxamide Chemical compound CC(O)=O.CC(O)=O.N([C@@H](CCN)C(=O)NCC=1C=CC=CC=1)C(=O)[C@@H]1CCCN1C(=O)CCN HSUGRPOJOBRRBK-SXBSVMRRSA-N 0.000 abstract 1
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- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
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- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 description 1
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- Cosmetics (AREA)
Abstract
The invention discloses an anti-aging polypeptide compound. The anti-aging polypeptide compound comprises the following components of, by weight, 20% to 30% of dipeptide diaminobutyroyl benzylamide diacetate, 10% to 30% of palmitoyl tripeptide-5, 5% to 10% of palmitoyl tetrapeptide-7, 5% to 10% of pentapeptide-3, 5% to 10% of hexapeptide-11, 5% to 10% of heptapeptide-6 and 20% to 30% of acetyl octapeptide-3. The sum of the weight percentages of all the components is 100%. The anti-aging polypeptide compound has the good application prospects in the facial mask essence preparation field, the skin can be made compact and smooth, dimness and roughness are avoided, and the skin returns to the young healthy state.
Description
Technical field
The present invention relates to a kind of complex, especially relate to a kind of defying age many victory peptide complexes, and the application of this defying age many victory peptide complexes.
Background technology
Perpetual youth is everyone dream, usual people it is generally acknowledged the first microgroove later just needing for 25 years old to occur defying age, but it is along with the life style of modern, the change of dietary habit and increasingly serious ambient pressure cause people to start more early to recognize antidotal importance, also more and more higher to the requirement of anti-aging product.
The outward manifestation of skin aging has microgroove usually, lack flexibility and occur relaxing, dry matt, the colour of skin is obscure, pigmentation is uneven.General anti-aging product is all mainly single for old and feeble produced problem, often effect not obvious.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of defying age many victory peptide complexes is provided.And the application of described defying age many victory peptide complexes in preparation facial mask essence is provided.
A kind of technical scheme realizing above-mentioned purpose is: a kind of defying age many victory peptide complexes, comprises the component of following percentage by weight:
The application of above-mentioned defying age many victory peptide complexes in preparation facial mask essence.
Have employed the technical scheme of a kind of defying age many victory peptide complexes of the present invention, compared with prior art, defying age many victory peptide complexes of the present invention combines forward position biotechnology technology, according to the antidotal different mechanism of action, containing seven kinds of victory peptide active component, be respectively dipeptides diaminobutyryl benzyl amide diacetin, palmityl tripeptides-5, Palmitoyl Tetrapeptide-7, pentapeptide-3, six peptides-11, seven peptides-6 and acetyl group octapeptide-3, these seven kinds victory peptide active component promote collagen protein and elastin laminin synthesis, reduce collagen degradation, smooth microgroove; Acceleration skin cell grows, and suppresses oxygen-derived free radicals and hydroxyl radical free radical; Block nerves is transmitted, and reduces expression crenulation stricture of vagina; Powerful antioxidant, suppresses photoaging; Repair impaired skin, rebuild epidermal structure, compact skin; Reduce inflammatory reaction, long-actingly to releive; Stimulate hyaluronic synthesis in body, endogenous moisturizing, makes skin full.The yeast activity thing added in addition, can active cell energy, promotes skin cell metabolism, bright color.
After application defying age of the present invention many victory peptide complexes in preparation facial mask essence, can effectively promote face skin profile, antagonism microgroove, recovers to compact elasticity, delicate soft and smooth, changes skin of face state on the whole.
Detailed description of the invention
The present inventor, in order to understand technical scheme of the present invention better, is described in detail below by embodiment particularly:
A kind of defying age many victory peptide complexes, comprises the component of following percentage by weight:
Above-mentioned raw materials is commercially available prod.
In defying age many victory peptide complexes of the present invention, dipeptides diaminobutyryl benzyl amide diacetin can suppress acetylcholinergic receptor to discharge, level and smooth pseudo wrinkle; Palmityl tripeptides-5 can be simulated human activin tissue growth factor TGF-β and be repaired impaired skin and hyaluronic acid synthesis; Palmitoyl Tetrapeptide-7 can improve skin microcirculation, diminishes inflammation, free radical and oxidation reaction, promotes collagen protein synthesis; Pentapeptide-3 can simulate the external natural mechanism of enkephalin, reduces histrionic muscles and shrinks, and suppresses wrinkle to be formed; Six peptides-11 can cell-cell adhesion effect, and prevent skin from relaxing, even skin tone, improves dim mute; Seven peptides-6 can improve deacetylation enzymatic activity, and DNA plerosis is damaged, and extend the fibroblast life-span; Acetyl group octapeptide-3 can block nerves transmission, reduces expression stricture of vagina, wrinkle.Defying age many victory peptide complexes of the present invention is applied in preparation facial mask essence, and the facial mask essence containing defying age many victory peptide complexes of the present invention, has obvious defying age repair function.
As can be seen here, defying age many victory peptide complexes of the present invention after application, utilizes the active essential ingredient of different defying age many victory peptides in preparation facial mask essence, effectively can promote collagen protein and elastin laminin synthesis; The activity of protease inhibition, reduces collagen degradation; Controlled oxidization reacts, scavenging free radicals; The wrinkle that minimizing nerve conduction produces undue muscular movement and formed; Reparation damaged dna damages, and rebuilds skin texture; Reduce inflammatory reaction, calm skin of releiving; Supplement moisture of skin, go down microgroove and coarse, thus make skin return to youth, compact, be rich in gloss and elastic health status.
Those of ordinary skill in the art will be appreciated that, above embodiment is only used to the present invention is described, and be not used as limitation of the invention, as long as in spirit of the present invention, all will drop in Claims scope of the present invention the change of the above embodiment, modification.
Claims (2)
1. defying age many victory peptide complexes, is characterized in that, comprises the component of following percentage by weight:
The percentage by weight sum of above-mentioned all components is 100%.
2. the application of defying age many victory peptide complexes as claimed in claim 1 in preparation facial mask essence.
Priority Applications (1)
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CN201510009992.9A CN104523449A (en) | 2015-01-08 | 2015-01-08 | Anti-aging polypeptide compound and application thereof |
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CN201510009992.9A CN104523449A (en) | 2015-01-08 | 2015-01-08 | Anti-aging polypeptide compound and application thereof |
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CN201510009992.9A Pending CN104523449A (en) | 2015-01-08 | 2015-01-08 | Anti-aging polypeptide compound and application thereof |
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Cited By (15)
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CN105878131A (en) * | 2016-06-08 | 2016-08-24 | 广州市创美时美容化妆品有限公司 | Anti-aging cosmetic composition with plant-cell active substances and polypeptide |
CN106038385A (en) * | 2016-06-08 | 2016-10-26 | 广州市创美时美容化妆品有限公司 | Cosmetic composition capable of stimulating collagen generation for wrinkle resistance |
CN106038351A (en) * | 2016-07-12 | 2016-10-26 | 深圳市维琪医药研发有限公司 | Polypeptide composition for smoothing wrinkles |
CN106265223A (en) * | 2016-05-12 | 2017-01-04 | 哈尔滨源茂达生物技术有限公司 | One peptide species anti-acne skin rejuvenating facial mask and preparation method thereof |
CN107157865A (en) * | 2017-07-25 | 2017-09-15 | 四川吉晟生物医药有限公司 | A kind of anti-wrinkle combined containing gadol extract and active peptides repairs cosmetics |
CN108379110A (en) * | 2018-05-16 | 2018-08-10 | 广州莎利曼尔生物科技有限公司 | Skin care compositions, skin care cream and preparation method thereof |
US10086035B2 (en) | 2016-02-04 | 2018-10-02 | ALASTIN Skincare, Inc. | Compositions and methods for invasive and non-invasive procedural skincare |
JP2018537464A (en) * | 2015-12-16 | 2018-12-20 | ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. | New use |
CN109199985A (en) * | 2018-11-16 | 2019-01-15 | 董志林 | A kind of anti-ageing Essence factory formula |
CN109908024A (en) * | 2019-04-23 | 2019-06-21 | 嫦娥创新(武汉)生物科技有限公司 | A kind of crease-resistant Firm lotion containing polypeptide |
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US10493011B2 (en) | 2017-08-03 | 2019-12-03 | ALASTIN Skincare, Inc. | Peptide compositions and methods for ameliorating skin laxity and body contour |
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JP2018537464A (en) * | 2015-12-16 | 2018-12-20 | ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. | New use |
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US10688147B2 (en) | 2016-02-04 | 2020-06-23 | ALASTIN Skincare, Inc. | Compositions and methods for invasive and non-invasive procedural skincare |
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CN106265223A (en) * | 2016-05-12 | 2017-01-04 | 哈尔滨源茂达生物技术有限公司 | One peptide species anti-acne skin rejuvenating facial mask and preparation method thereof |
CN105878131A (en) * | 2016-06-08 | 2016-08-24 | 广州市创美时美容化妆品有限公司 | Anti-aging cosmetic composition with plant-cell active substances and polypeptide |
CN106038385A (en) * | 2016-06-08 | 2016-10-26 | 广州市创美时美容化妆品有限公司 | Cosmetic composition capable of stimulating collagen generation for wrinkle resistance |
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