CN104474217A - Traditional Chinese medicine preparation for improving neuralgic amyotrophy and preparation method thereof - Google Patents
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Abstract
The invention discloses a traditional Chinese medicine preparation for improving neuralgic amyotrophy. The traditional Chinese medicine preparation is prepared from 20-40 parts by weight of ligusticum wallichii, 3-7 parts by weight of scallion, 15-25 parts by weight of typhonium giganteum, 15-25 parts by weight of deerhorn glue, 10-20 parts by weight of herba asari, 6-18 parts by weight of rhizoma drynariae, 20-30 parts by weight of dragon bone, 25-40 parts by weight of acanthopanax root, 8-13 parts by weight of raw licorice root, 13-28 parts by weight of bark of ash and 15-25 parts by weight of Chinese angelica. The traditional Chinese medicine preparation has the characteristics of preparation simpleness, taking convenience, carrying convenience and long-term use feasibility. The traditional Chinese medicine preparation has effects of dispelling wind and dredging collaterals, relaxing muscles and tendons and promoting blood circulation, supporting body resistance, reinforcing qi and nourishing blood, and promoting blood circulation to remove blood stasis and relieving pain.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of oral liquid improving neurotic atrophy and preparation method thereof.
Background technology
Amyotrophy refers to striped muscle malnutrition, and the meat fiber muscle volume that causes such as even to disappear that attenuates reduces.The cause of disease mainly contains: neurogenic muscular atrophy, muscle-derived amyotrophy, muscular atrophy of disuse and other reasons amyotrophy.Muscle nutrition situation, except the pathological change of muscular tissue itself, more has substantial connection with nervous system.Diseases of spinal cord often causes muscular dystrophy and amyotrophy occurs.Amyotrophy patient is due to amyotrophy, myasthenia and long-term bed, and easy Complicating Pneumonia In Patients, decubital ulcer etc., bulbar paralysis symptom appears in Most patients in addition, forms great threat to patient vitals.Amyotrophy patient is except sending for a doctor to improve, and oneself's medical treatment is very important.
Neurogenic muscular atrophy is when neural impulse arrives, teleneuron release chemical mediator acetylcholine, the receptor on the latter and soleplate temporarily combines, and increases this place's sarolemma to the permeability of sodium, make extracellular Na+ion enter cell, thus make the transmembrane potential depolarization of endplate regions; Namely cause after reaching certain threshold value and sarolemma produces action potential around.Action potential is transmitted to sarcoplasmic reticulum, impels it to discharge calcium ion to sarcoplasm; The latter can impel adenosine triphosphate to decompose, and releases energy and some protein molecular in myocyte is closely agreed with, causing the contraction of myocyte's length.The common reason of neuropathic muscular atrophy is useless use, malnutrition, ischemia and poisoning.The conductive impairment that anterior angle pathological changes, nerve root, plexus nervorum, perineural amyotrophy pathological changes etc. all can cause neural excitation to get excited, thus part muscle fiber is given up use, produce muscular atrophy of disuse.On the other hand when after lower motor neuron any position infringement, the acetylcholine of its tip position release reduces, and sympathetic nerve Nutrition weakens and causes amyotrophy.Myogenicity amyotrophy is by the disease of muscle own, may also comprise some other factor, as the muscular dystrophy patient of shoulder belt or facio scapulo humeral type, turns out to be spinal muscular atrophy by morphological examination.
Application publication number CN 103432426 A(application number 201310416190.0) Chinese patent literature disclose a kind of Chinese medicinal tablet for the treatment of neuro-muscular atrophy, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Aconiti 20-45 part, Rhizoma Gastrodiae 20-45 part, Cortex Cinnamomi 20-45 part, Radix Clematidis 20-45 part, Radix Astragali 30-50 part, Bulbus Lilii 30-50 part, Radix Polygalae 30-50 part, Pheretima 1-5 part, Scorpio 1-5 part.
In a word, Chinese medicine achieves good curative effect improving in primary disease, but also there are some problems: clinically to activating blood circulation to dissipate blood stasis and dredge the collateral, expelling wind and cold, and understand things pain-stopping is desirable not enough, has much room for improvement to improving the misery that neuro-muscular atrophy brings.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide and a kind ofly prepare simple, taking convenience, be easy to carry, easily a kind of of clothes improves Chinese medicine preparation of neuro-muscular atrophy and preparation method thereof for a long time.This Chinese medicine preparation has dispelling wind and removing obstruction in the collateral, relaxing muscles and tendons to promote blood circulation, the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, effect of promoting blood circulation, removing blood stasis and relieving pain.
Technical scheme of the present invention is:
Improve a Chinese medicine preparation for neuro-muscular atrophy, be prepared from by the crude drug of following weight proportioning: Rhizoma Chuanxiong 20-40 part, Herba Alii fistulosi 3-7 part, Herba Typhonii gigantei 15-25 part, Colla cornus cervi 15-25 part, Herba Asari 10-20 part, Rhizoma Drynariae 6-18 part, Os Draconis 20-30 part, Radix Et Caulis Acanthopanacis Senticosi 25-40 part, Radix Glycyrrhizae 8-13 part, Radix Gentianae Macrophyllae 13-28 part and Radix Angelicae Sinensis 15-25 part.
Foregoing Chinese medicine preparation, preferred scheme is, is prepared from by the crude drug of following weight proportioning: Rhizoma Chuanxiong 25-35 part, Herba Alii fistulosi 4-6 part, Herba Typhonii gigantei 18-23 part, Colla cornus cervi 18-23 part, Herba Asari 13-18 part, Rhizoma Drynariae 10-14 part, Os Draconis 23-28 part, Radix Et Caulis Acanthopanacis Senticosi 30-35 part, Radix Glycyrrhizae 9-11 part, Radix Gentianae Macrophyllae 18-20 part and Radix Angelicae Sinensis 18-23 part.
Foregoing Chinese medicine preparation, better preferred scheme is prepared from by the crude drug of following weight proportioning: Rhizoma Chuanxiong 30 parts, Herba Alii fistulosi 5 parts, Herba Typhonii gigantei 20 parts, Colla cornus cervi 20 parts, Herba Asari 15 parts, Rhizoma Drynariae 12 parts, Os Draconis 25 parts, Radix Et Caulis Acanthopanacis Senticosi 32 parts, Radix Glycyrrhizae 10 parts, Radix Gentianae Macrophyllae 19 parts and Radix Angelicae Sinensis 20 parts.
According to the preparation method improving the Chinese medicine preparation of neuro-muscular atrophy noted earlier, step is as follows:
(1) first Rhizoma Chuanxiong, Herba Typhonii gigantei and Radix Angelicae Sinensis are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in the deep fat dryouied, until stir-fry to when going out fragrance, with strainer, Rhizoma Chuanxiong, Herba Typhonii gigantei and Pericarpium Zanthoxyli taken out, continue little fire heating after 1-5 minute, add Colla cornus cervi, after fluid is cooled to 30-40 DEG C, is distributed into air-tight bottle and obtains medicine for external use oil;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 20-30 minute, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 5-10 minute with rolling pin, stand-by;
(4) Chinese liquor of Herba Asari, Rhizoma Drynariae, Radix Et Caulis Acanthopanacis Senticosi, Radix Glycyrrhizae and Radix Gentianae Macrophyllae 30-40 DEG C (preferably 35 DEG C) is placed in sealing and standing 1-3 days (preferably 2 days) in crock, be placed in the hot pot dryouied, little fire is fried to 10-20 minute, and taking-up cools, and it is stand-by to grind to form smalls;
(5) step (2)-(4) gains are together placed in marmite; add mixed material medicine gross weight 1-3 water doubly; intense fire is heated to boiling; continue after 3-5 minute (preferably 4 minutes); change slow fire boiling, the process Chinese medicine of decoction constantly stirs, in time becoming thick paste; cease fire, cool bottling and namely obtain oral thick paste.
Foregoing preparation method, preferred scheme is: Rhizoma Chuanxiong, Herba Typhonii gigantei and Pericarpium Zanthoxyli take out by step (1) strainer, continues little fire heating and (preferably Rhizoma Chuanxiong, Herba Typhonii gigantei and Pericarpium Zanthoxyli is taken out with strainer, continue little fire heating after 3 minutes) after 2-4 minute.
Foregoing preparation method, preferred scheme is: after step (1) fluid is cooled to 33-38 DEG C, is distributed into air-tight bottle (preferred oil liquid be cooled to 35 DEG C after, be distributed into air-tight bottle).
Foregoing preparation method, preferred scheme is: step (2) is placed in the upper big fire of iron plate and dries 23-28 minute (be preferably placed in the upper big fire of iron plate and dry 25 minutes).
Foregoing preparation method, preferred scheme is: step (3) Herba Alii fistulosi mud ultraviolet sterilization 7-9 minute (preferred Herba Alii fistulosi mud ultraviolet sterilization 8 minutes).
Foregoing preparation method, preferred scheme is: the little fire of step (4) is fried to 13-18 minute (preferred little fire was fried to 15 minutes).
Foregoing preparation method, preferred scheme is: step (5) adds mixed material medicine gross weight 1.5-2.5 water (preferably adding the water of mixed material medicine gross weight 2 times) doubly.
Using method: reach the best for making the present invention and improve effect, boiled water is washed open and is taken half an hour after breakfast, lunch and dinner for preparation and the thick paste that obtain, and each 5 grams 10 days is a course for the treatment of, and the medicine of gained is oily, spreads upon the position of atrophy, has smeared rear soft left and right each three circles up and down.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Rhizoma Chuanxiong: Rhizoma Chuanxiong is a kind of Chinese medicinal plant, is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, the pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, and the up mountain peak that reaches is pushed up; Enter blood system again, descendingly reach the sea of blood.Blood circulation promoting and blood stasis dispelling effect is extensive, the suitable various disease of stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.It is gas medicine in blood that former times people calls Rhizoma Chuanxiong, the functions such as pungent loose, the resolving depression of its residence of dangerous speech, sensible, pain relieving.
Herba Alii fistulosi: another name and thing grass, onion, dish primary, HUOCONG, the four seasons Herba Alii fistulosi.Flavor efficacy is pungent, and temperature, enters lung, stomach warp.Exterior-excess hollow, rise to fall more and lack, merit is specially dispersed and is activated yang, can expelling wind and cold pathogens, and diaphoresis expelling pathogenic factors from muscles, for improving the mild of typhoid fever, cold and heat headache; Again can item, sharp key, relieving constipation, activate yang gas and loose YIN-cold, for improving QI and blood cohesion, dizzy headache, QI stagnated by cold, abdominal distention is suffered from abdominal pain, and bladder qi dysfunction and dysuria etc.; In addition still tool removing toxic substances, hemostatic function.Energy activating yang to invigorate blood circulation, anthelmintic removing toxic substances, relieving the exterior syndrome by diaphoresis.Cure mainly the diseases such as anemofrigid cold mild, carbuncle sore tumefacting virus, dysentery faint pulse, cold coagulation stomachache, dysuria, flu, wind and cold, headache, YIN-cold stomachache, malnutrition due to parasitic infestation internal resistance, dysentery etc. are had a better role.1. antipyretic, eliminate the phlegm: the medicine wet goods effective ingredient of Herba Alii fistulosi, have and stimulate health sweat gland, reach the effect of diaphoresis heat radiation; Scallion oil stimulates upper respiratory tract, makes sticky expectorant be easy to bring up.2. facilitating digestion absorbs: Herba Alii fistulosi also has the effect stimulating body digestive juice secretion, can spleen benefiting and stimulating the appetite, appetite stimulator.3. antibacterial, antiviral 4. cancer-resisting.
Herba Typhonii gigantei: another name Rhizoma Typhonium Gigantei (Rhizoma Typhonii), milk in vain attached, red male star, numb taro, the wild Rhizoma Pinelliae, Cor Gigeriae Galli are attached in vain.Flavor efficacy acrid, sweet, warm.Poisonous.Return stomach, Liver Channel.Function drying dampness to eliminate phlegm, timid wind relieving convulsion, removing toxic substances powder knot.Be applicable to the stagnant network of wind-phlegm, facial hemiparalysis, apoplexy abundant expectoration, aphasia hemiplegia, tetanus and headache due to cold-damp; External is used for sucutaneous nodule scrofula, venom.
Colla cornus cervi: this product is that deltiod is fast.Yellowish-brown or rufous, translucent, yellow-white froth bed is arranged at some top.Matter is crisp, frangible, section light.Feeble QI, taste is micro-sweet.Colla cornus cervi, temperature compensation Liver and kidney, beneficial intensive culture blood.Dizzy for blood deficiency, the acid of waist knee joint is cold, and asthenia is become thin.
Herba Asari: pungent, temperature.GUIXIN, lung, kidney channel.Have another name called: magnificent Herba Asari, little Xin, few pungent, careless Herba Asari of basin etc., belong to Aristolochiales, Aristolochiaceae perennial herb, dispels the wind, cold expelling, row water, has one's ideas straightened out.Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.Herba Asari can outer dispersing wind and cold, again can in dispel YIN-cold, pain relieving simultaneously, antitussive effect are better.
Rhizoma Drynariae: Rhizoma Drynariae, another name: precipice Rhizoma Zingiberis Recens, rock connect Rhizoma Zingiberis Recens, delevay drynaria, the broken benefit of meat, the broken benefit of stone, flying apsaras Mus, Niu Feilong, sudden wind, moth grass.The kidney invigorating bone strengthening, continues and hinders pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.
Os Draconis: base is former: for mammal in ancient times resembles the Skeletal Fossils of class, rhinoceros class, Hippocampal cortex, bovine, deer class etc.Composition: Os Draconis, mainly containing calcium carbonate and calcium phosphate, still contain ferrum, potassium, sodium, chlorine, sulfate radical etc.The property of medicine: puckery, sweet, flat.GUIXIN, liver, kidney, large intestine channel.Function cures mainly: tranquilizing mind, suppressing the hyperactive liver and subsiding YANG, restrains astringent or styptic treatment for spontaneous sweating.Cure mainly cardiopalmus, seized with terror swollen, insomnia, forgetful, infantile convulsion, demented, dizzy, spontaneous sweating, the seminal emission enuresis, bleeding not during menses, chronic diarrhea and dysentery, ulcer does not close up and eczema for a long time.Compatibility and incompatibility of drugs: the careful clothes of the excess-heat person of stagnating.
Radix Et Caulis Acanthopanacis Senticosi: base is former: be the root of studies on plants of Acanthopanax Miq. in Araliaceae Radix Et Caulis Acanthopanacis Senticosi, rhizome or stem and leaf.Composition: root contains eleutheroside A, B, B1, C, D, E, eleutheroside A and daucosterol, Syringin and ligustrin; Root also contains sinapyladehyde glucoside, coniferyl aldehyde glucoside etc.The property of medicine: " Shaanxi Chinese medicinal herbal ": " pungent, temperature, enters liver, kidney two warp." function cures mainly: QI invigorating, the kidney invigorating, calms the nerves, and invigorates blood circulation.Cure mainly insufficiency of the spleen weak, deficiency of vital energy edema, insomnia and dreamful sleep, forgetful, soreness of the waist and knees, children's's walking retardation in children, thoracic obstruction pain, chronic cough, rheumatic arthralgia.
Radix Glycyrrhizae: another name Glycyrrhizae, close sweet, close grass, state are old, Radix Glycyrrhizae, Herba Hedyotis cantonensis, sweet root, excellent grass system pulse family herbaceos perennial.The traditional Chinese medical science thinks that it has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine, nature and flavor: sweet, flat.Gui Jing: GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Radix Gentianae Macrophyllae: another name ground is smoked, mountain dish, mushroom are careless, faggot.Nature and flavor are bitter, are slightly cold.Return liver, gallbladder meridian.There is reconciling superficies and interior, soothing the liver, effect of yang invigorating.For cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterine prolapse, menoxenia.
Radix Angelicae Sinensis, call dryly to return, the Qin which, western Radix Angelicae Sinensis, Min Radix Angelicae Sinensis, Radix Angelicae Sinensis, Radix Angelicae Sinensis body, contain that Radix Angelicae Sinensis, Radix Angelicae Sinensis are bent, Radix Angelicae Gigatis, it is herbaceos perennial, and its root can be used as medicine, and is one of the most frequently used Chinese medicine.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation.For blood deficiency, shallow complexion, dizzy cardiopalmus; Blood deficiency, or have the stagnant menoxenia of the stasis of blood, amenorrhea, dysmenorrhea concurrently; The pain such as deficient cold type stomachache, angina pectoris, rheumatic arthralgia, traumatic injury card; Dryness of the intestine constipation; Chronic cough is panted.
Chinese medicine preparation of the present invention meets the principle that disease improvement debated by Chinese medicine.The medical material selected is divided into thick paste for oral administration and medicine for external use oil, inside and outside treat simultaneously, improve more comprehensive, affected area administration is rapider, lasting medicine, take into account inside and outside belonging to, the migraine prescription for the treatment of both the principal and secondary aspects of a disease, has fabulous improvement result to migraine, not only there is good improvement result to neuro-muscular atrophy, very very effective in cure to trigeminal neuralgia, in addition, excellent results of the present invention also shows:
1,effect that in selected materials, Rhizoma Chuanxiong, Herba Alii fistulosi, Colla cornus cervi, Radix Glycyrrhizae and Radix Gentianae Macrophyllae have blood stasis dispelling, invigorate blood circulation, other crude drug are improved bones and muscles pain, calm the nerves, sensible effect, the crude drug of different efficacies is combined, serve relaxing muscles and tendons to promote blood circulation, the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, promoting blood circulation, removing blood stasis and relieving pain, improves effect of neuro-muscular atrophy;
2,this prescription meets Chinese medicine principle and neuro-muscular atrophy patient body and mind feature completely, under the prerequisite of general principle, can have different prescription according to different crowd, and function is different.
3,medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1improve the Chinese medicine preparation of neuro-muscular atrophy, get the raw materials ready (getting 20g for every part) by following weight parts: Rhizoma Chuanxiong 20 parts, Herba Alii fistulosi 3 parts, Herba Typhonii gigantei 15 parts, Colla cornus cervi 15 parts, Herba Asari 10 parts, Rhizoma Drynariae 6 parts, Os Draconis 20 parts, Radix Et Caulis Acanthopanacis Senticosi 25 parts, Radix Glycyrrhizae 8 parts, Radix Gentianae Macrophyllae 13 parts and Radix Angelicae Sinensis 15 parts.
The above-mentioned preparation method improving the Chinese medicine preparation of neuro-muscular atrophy:
(1) first Rhizoma Chuanxiong, Herba Typhonii gigantei and Radix Angelicae Sinensis are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in the deep fat dryouied, until stir-fry to when going out fragrance, with strainer, Rhizoma Chuanxiong, Herba Typhonii gigantei and Pericarpium Zanthoxyli taken out, continue little fire heating after 1 minute, add Colla cornus cervi, after fluid is cooled to 30 DEG C, is distributed into air-tight bottle and obtains medicine for external use oil;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 20 minutes, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 5 minutes with rolling pin, stand-by;
(4) Herba Asari, Rhizoma Drynariae, Radix Et Caulis Acanthopanacis Senticosi, Radix Glycyrrhizae and the Radix Gentianae Macrophyllae Chinese liquor of 30 DEG C to be placed in crock sealing and standing 1 day, be placed in the hot pot dryouied, little fire was fried to 10 minutes, and taking-up cools, and it is stand-by to grind to form smalls;
(5) be together placed in marmite by step (2)-(4) gains, add the water of mixed material medicine gross weight 1 times, intense fire is heated to boiling; continue after 3 minutes, change slow fire boiling, the process Chinese medicine of decoction constantly stirs; in time becoming thick paste, cease fire, cool bottling and namely obtain oral thick paste.
typical case one: king XX, female, 45 years old, Jinan, Shandong Province people from Jiyang, peasant.The appearance face Hyperalgesia of unknown cause, bicker is sagging without reason, and neck is soft, the symptom that two lower limb are ached, and originally thinks and suffers from cold, also do not take notice of very much, and just taken the medicine of some pain relievings to it, after medication, symptom improves, afterwards just drug withdrawal.General one month, again there is numb limbs and tense tendons, the disease such as weak, tired, and sensation walking comparatively difficulty, household is very worried, it is just with to do comprehensive inspection to large hospital, be diagnosed as neurogenic muscular atrophy, because patient does not want the school work delaying oneself, just require to take gained oral liquid of the present invention.
Give the oral embodiment of the present invention 1 gained preparation and with the use of the embodiment of the present invention 1 gained medicine oil, after 5 days, above-mentioned symptom be improved significantly, the mental status is very good, after continuing to have taken 1 course for the treatment of, substantially do not recur, continue again to take 1 course for the treatment of, above-mentioned symptom disappears substantially, without recurrence after drug withdrawal.
embodiment 2improve the Chinese medicine preparation of neuro-muscular atrophy, get the raw materials ready (getting 20g for every part) by following weight parts: Rhizoma Chuanxiong 40 parts, Herba Alii fistulosi 7 parts, Herba Typhonii gigantei 25 parts, Colla cornus cervi 25 parts, Herba Asari 20 parts, Rhizoma Drynariae 18 parts, Os Draconis 30 parts, Radix Et Caulis Acanthopanacis Senticosi 40 parts, Radix Glycyrrhizae 13 parts, Radix Gentianae Macrophyllae 28 parts and Radix Angelicae Sinensis 25 parts.
The preparation method improving the Chinese medicine preparation of neuro-muscular atrophy is:
(1) first Rhizoma Chuanxiong, Herba Typhonii gigantei and Radix Angelicae Sinensis are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in the deep fat dryouied, until stir-fry to when going out fragrance, with strainer, Rhizoma Chuanxiong, Herba Typhonii gigantei and Pericarpium Zanthoxyli taken out, continue little fire heating after 5 minutes, add Colla cornus cervi, after fluid is cooled to 40 DEG C, is distributed into air-tight bottle and obtains medicine for external use oil;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 30 minutes, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 10 minutes with rolling pin, stand-by;
(4) Herba Asari, Rhizoma Drynariae, Radix Et Caulis Acanthopanacis Senticosi, Radix Glycyrrhizae and the Radix Gentianae Macrophyllae Chinese liquor of 40 DEG C to be placed in crock sealing and standing 3 days, be placed in the hot pot dryouied, little fire was fried to 20 minutes, and taking-up cools, and it is stand-by to grind to form smalls;
(5) be together placed in marmite by step (2)-(4) gains, add the water of mixed material medicine gross weight 3 times, intense fire is heated to boiling; continue after 5 minutes, change slow fire boiling, the process Chinese medicine of decoction constantly stirs; in time becoming thick paste, cease fire, cool bottling and namely obtain oral thick paste.
embodiment 3improve the Chinese medicine preparation of neuro-muscular atrophy, get the raw materials ready (getting 20g for every part) by following weight parts: Rhizoma Chuanxiong 25 parts, Herba Alii fistulosi 4 parts, Herba Typhonii gigantei 18 parts, Colla cornus cervi 18 parts, Herba Asari 13 parts, Rhizoma Drynariae 10 parts, Os Draconis 23 parts, Radix Et Caulis Acanthopanacis Senticosi 30 parts, Radix Glycyrrhizae 9 parts, Radix Gentianae Macrophyllae 18 parts and Radix Angelicae Sinensis 18 parts.
The preparation method improving the Chinese medicine preparation of neuro-muscular atrophy is:
(1) first Rhizoma Chuanxiong, Herba Typhonii gigantei and Radix Angelicae Sinensis are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in the deep fat dryouied, until stir-fry to when going out fragrance, with strainer, Rhizoma Chuanxiong, Herba Typhonii gigantei and Pericarpium Zanthoxyli taken out, continue little fire heating after 2 minutes, add Colla cornus cervi, after fluid is cooled to 33 DEG C, is distributed into air-tight bottle and obtains medicine for external use oil;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 23 minutes, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 7 minutes with rolling pin, stand-by;
(4) Herba Asari, Rhizoma Drynariae, Radix Et Caulis Acanthopanacis Senticosi, Radix Glycyrrhizae and the Radix Gentianae Macrophyllae Chinese liquor of 33 DEG C to be placed in crock sealing and standing 1.5 days, be placed in the hot pot dryouied, little fire was fried to 13 minutes, and taking-up cools, and it is stand-by to grind to form smalls;
(5) be together placed in marmite by step (2)-(4) gains, add the water of mixed material medicine gross weight 1.5 times, intense fire is heated to boiling; continue after 3.5 minutes, change slow fire boiling, the process Chinese medicine of decoction constantly stirs; in time becoming thick paste, cease fire, cool bottling and namely obtain oral thick paste.
typical case two:woods XX, man 42 years old, Jinan, Shandong Province personage, cadre at their posts, before 2 years, the appearance right hand of unknown cause is unable, originally at the beginning because look after children, caused by fatigue, just to paste several forcing on, but effect bad, after 5 days, grip goes down, and occurs that finger stretches the symptom of difficulty subsequently, cannot be autonomous have a meal, go examination in hospital to be finally diagnosed as right hand neurogenic muscular atrophy, at present without effective Therapeutic Method, purchase of coming after knowing oral liquid of the present invention is treated.
Take the embodiment of the present invention 3 gained Chinese medicine preparation and with the use of embodiment 3 gained medicine oil, after 1 course for the treatment of, patient's right hand can take thing, do some simple actions, symptom after taking two courses for the treatment of before patient is improved substantially, and can oneself have a meal, after continuing to take 2 courses for the treatment of, malaise symptoms disappears, patient's self-induction is fully recovered, and is in the best of spirit.
embodiment 4improve the Chinese medicine preparation of neuro-muscular atrophy, get the raw materials ready (getting 20g for every part) by following weight parts: Rhizoma Chuanxiong 35 parts, Herba Alii fistulosi 6 parts, Herba Typhonii gigantei 23 parts, Colla cornus cervi 23 parts, Herba Asari 18 parts, Rhizoma Drynariae 14 parts, Os Draconis 28 parts, Radix Et Caulis Acanthopanacis Senticosi 35 parts, Radix Glycyrrhizae 11 parts, Radix Gentianae Macrophyllae 20 parts and Radix Angelicae Sinensis 23 parts.
The preparation method improving the Chinese medicine preparation of neuro-muscular atrophy is:
(1) first Rhizoma Chuanxiong, Herba Typhonii gigantei and Radix Angelicae Sinensis are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in the deep fat dryouied, until stir-fry to when going out fragrance, with strainer, Rhizoma Chuanxiong, Herba Typhonii gigantei and Pericarpium Zanthoxyli taken out, continue little fire heating after 4 minutes, add Colla cornus cervi, after fluid is cooled to 38 DEG C, is distributed into air-tight bottle and obtains medicine for external use oil;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 28 minutes, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 9 minutes with rolling pin, stand-by;
(4) Herba Asari, Rhizoma Drynariae, Radix Et Caulis Acanthopanacis Senticosi, Radix Glycyrrhizae and the Radix Gentianae Macrophyllae Chinese liquor of 38 DEG C to be placed in crock sealing and standing 2.5 days, be placed in the hot pot dryouied, little fire was fried to 18 minutes, and taking-up cools, and it is stand-by to grind to form smalls;
(5) be together placed in marmite by step (2)-(4) gains, add the water of mixed material medicine gross weight 2.5 times, intense fire is heated to boiling; continue after 4.5 minutes, change slow fire boiling, the process Chinese medicine of decoction constantly stirs; in time becoming thick paste, cease fire, cool bottling and namely obtain oral thick paste.
embodiment 5improve the Chinese medicine preparation of neuro-muscular atrophy, get the raw materials ready (getting 20g for every part) by following weight parts: Rhizoma Chuanxiong 30 parts, Herba Alii fistulosi 5 parts, Herba Typhonii gigantei 20 parts, Colla cornus cervi 20 parts, Herba Asari 15 parts, Rhizoma Drynariae 12 parts, Os Draconis 25 parts, Radix Et Caulis Acanthopanacis Senticosi 32 parts, Radix Glycyrrhizae 10 parts, Radix Gentianae Macrophyllae 19 parts and Radix Angelicae Sinensis 20 parts.
The preparation method improving the Chinese medicine preparation of neuro-muscular atrophy is:
(1) first Rhizoma Chuanxiong, Herba Typhonii gigantei and Radix Angelicae Sinensis are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in the deep fat dryouied, until stir-fry to when going out fragrance, with strainer, Rhizoma Chuanxiong, Herba Typhonii gigantei and Pericarpium Zanthoxyli taken out, continue little fire heating after 3 minutes, add Colla cornus cervi, after fluid is cooled to 35 DEG C, is distributed into air-tight bottle and obtains medicine for external use oil;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 25 minutes, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 8 minutes with rolling pin, stand-by;
(4) Herba Asari, Rhizoma Drynariae, Radix Et Caulis Acanthopanacis Senticosi, Radix Glycyrrhizae and the Radix Gentianae Macrophyllae Chinese liquor of 35 DEG C to be placed in crock sealing and standing 2 days, be placed in the hot pot dryouied, little fire was fried to 15 minutes, and taking-up cools, and it is stand-by to grind to form smalls;
(5) be together placed in marmite by step (2)-(4) gains, add the water of mixed material medicine gross weight 2 times, intense fire is heated to boiling; continue after 4 minutes, change slow fire boiling, the process Chinese medicine of decoction constantly stirs; in time becoming thick paste, cease fire, cool bottling and namely obtain oral thick paste.
test example 1embodiment 5 gained improves the clinical practice of the Chinese medicine preparation of neuro-muscular atrophy: patient 400 example choosing neuro-muscular atrophy in 10 hospitals, before test 1 week, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group takes embodiment 5 products obtained therefrom, and matched group takes other medicine (conventional medication such as JINGFUKANG, WANTONG JINGU PIAN, neck waist recovering capsule).Curative effect situation criterion: cure: take embodiment 5 gained tablet and after coordinating embodiment 5 gained medicine oil, malaise symptoms has clear improvement, and pain disappears substantially; Effective: to take embodiment 5 gained tablet and after coordinating embodiment 5 gained medicine oil, malaise symptoms makes moderate progress, and pain alleviates to some extent; Invalid: after taking this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1:
Gained Chinese medicine preparation effective percentage of the present invention is up to 99%, and cure rate is up to 97%, and successful is better than experimental group, and takes product of the present invention 5 days, and malaise symptoms improves, and pain alleviates to some extent; Take 10 days, malaise symptoms improves or disappears, and pain disappears substantially; Take 20 days, malaise symptoms improves or disappears, and some patients self-induction is fully recovered.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (8)
1. improve a Chinese medicine preparation for neuro-muscular atrophy, it is characterized in that: be prepared from by the crude drug of following weight proportioning: Rhizoma Chuanxiong 20-40 part, Herba Alii fistulosi 3-7 part, Herba Typhonii gigantei 15-25 part, Colla cornus cervi 15-25 part, Herba Asari 10-20 part, Rhizoma Drynariae 6-18 part, Os Draconis 20-30 part, Radix Et Caulis Acanthopanacis Senticosi 25-40 part, Radix Glycyrrhizae 8-13 part, Radix Gentianae Macrophyllae 13-28 part and Radix Angelicae Sinensis 15-25 part.
2. Chinese medicine preparation according to claim 1, is characterized in that: be prepared from by the crude drug of following weight proportioning: Rhizoma Chuanxiong 25-35 part, Herba Alii fistulosi 4-6 part, Herba Typhonii gigantei 18-23 part, Colla cornus cervi 18-23 part, Herba Asari 13-18 part, Rhizoma Drynariae 10-14 part, Os Draconis 23-28 part, Radix Et Caulis Acanthopanacis Senticosi 30-35 part, Radix Glycyrrhizae 9-11 part, Radix Gentianae Macrophyllae 18-20 part and Radix Angelicae Sinensis 18-23 part.
3. Chinese medicine preparation according to claim 1, is characterized in that: be prepared from by the crude drug of following weight proportioning: Rhizoma Chuanxiong 30 parts, Herba Alii fistulosi 5 parts, Herba Typhonii gigantei 20 parts, Colla cornus cervi 20 parts, Herba Asari 15 parts, Rhizoma Drynariae 12 parts, Os Draconis 25 parts, Radix Et Caulis Acanthopanacis Senticosi 32 parts, Radix Glycyrrhizae 10 parts, Radix Gentianae Macrophyllae 19 parts and Radix Angelicae Sinensis 20 parts.
4. basis improves the preparation method of the Chinese medicine preparation of neuro-muscular atrophy according to claim 4, it is characterized in that: step is as follows:
(1) first Rhizoma Chuanxiong, Herba Typhonii gigantei and Radix Angelicae Sinensis are cleaned, break into the block of Pericarpium Zanthoxyli size, drain away the water, be placed in the deep fat dryouied, until stir-fry to when going out fragrance, with strainer, Rhizoma Chuanxiong, Herba Typhonii gigantei and Pericarpium Zanthoxyli taken out, continue little fire heating after 1-5 minute, add Colla cornus cervi, after fluid is cooled to 30-40 DEG C, is distributed into air-tight bottle and obtains medicine for external use oil;
(2) Os Draconis are broken into the block of coin-size, be placed in the upper big fire of iron plate and dry 20-30 minute, cool that to grind to form smalls stand-by;
(3) by Herba Alii fistulosi defoliation, Bulbus Allii Fistulosi is cut into the block of small rice grain size by knife, being placed in gauze, is pounded Herba Alii fistulosi mud ultraviolet sterilization 5-10 minute with rolling pin, stand-by;
(4) Chinese liquor of Herba Asari, Rhizoma Drynariae, Radix Et Caulis Acanthopanacis Senticosi, Radix Glycyrrhizae and Radix Gentianae Macrophyllae 30-40 DEG C (preferably 35 DEG C) is placed in sealing and standing 1-3 days (preferably 2 days) in crock, be placed in the hot pot dryouied, little fire is fried to 10-20 minute, and taking-up cools, and it is stand-by to grind to form smalls;
(5) step (2)-(4) gains are together placed in marmite; add mixed material medicine gross weight 1-3 water doubly; intense fire is heated to boiling; continue after 3-5 minute (preferably 4 minutes); change slow fire boiling, the process Chinese medicine of decoction constantly stirs, in time becoming thick paste; cease fire, cool bottling and namely obtain oral thick paste.
5. preparation method according to claim 4, it is characterized in that: Rhizoma Chuanxiong, Herba Typhonii gigantei and Pericarpium Zanthoxyli take out by step (1) strainer, continue little fire heating (preferably with strainer, Rhizoma Chuanxiong, Herba Typhonii gigantei and Pericarpium Zanthoxyli to be taken out, continue little fire heating after 3 minutes) after 2-4 minute.
6. preparation method according to claim 4, is characterized in that: after step (1) fluid is cooled to 33-38 DEG C, is distributed into air-tight bottle (preferred oil liquid be cooled to 35 DEG C after, be distributed into air-tight bottle).
7. preparation method according to claim 4, is characterized in that: step (2) is placed in the upper big fire of iron plate and dries 23-28 minute (be preferably placed in the upper big fire of iron plate and dry 25 minutes).
8. preparation method according to claim 4, is characterized in that: step (3) Herba Alii fistulosi mud ultraviolet sterilization 7-9 minute (preferred Herba Alii fistulosi mud ultraviolet sterilization 8 minutes).
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