CN104474154A - Traditional Chinese medicine for treating cold fever and preparation method of traditional Chinese medicine - Google Patents
Traditional Chinese medicine for treating cold fever and preparation method of traditional Chinese medicine Download PDFInfo
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- CN104474154A CN104474154A CN201410823297.1A CN201410823297A CN104474154A CN 104474154 A CN104474154 A CN 104474154A CN 201410823297 A CN201410823297 A CN 201410823297A CN 104474154 A CN104474154 A CN 104474154A
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Abstract
The invention discloses a traditional Chinese medicine for treating cold fever and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine is mainly prepared from the following raw materials in parts by weight: 15-30 parts ofalternantherasessilis, 8-16 parts of rhizomacynanchistauntonii, 15-20 parts of kudzuvine roots, 9-15 parts of radix sanguisorbae, 6-10 parts of roots of threeleafcayratia, 5-12 parts of Indian stringbush roots, 8-14 parts of ageratum conyzoides, 9-15 parts of andrographispaniculata, 4-8 parts of pararuelliadelauayana, 10-20 parts of lonicera japonica, 6-9 parts of peucedanumturgeniifolium and 8-12 parts of liquorice. The traditional Chinese medicine for treating cold fever works quickly, is safe, has no toxic or side effects and treats both manifestation and root causes.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine for the treatment of cat fever and preparation method thereof.
Background technology
Cat fever refers to that flu usually can cause fever symptoms, and the generation of flu is empty mainly due to body, and resistance against diseases weakens and causes.When weather drastic change, inside and outside human body, function can not adapt to, and pathogen is taken advantage of a weak point in opponent's defence by fur, mouth and nose and entering, and causes a series of heating paresthesia.Heating refers to that pyrogen directly acts on thermotaxic centre, and the heat production that heat center dysfunction or a variety of causes cause is too much, heat radiation reduces, and causes body temperature to increase to over the situation of normal range.Flu is divided into the types such as wind and cold, wind heat, heat-damp in summer, exterior cold and interior heat on tcm clinical practice.Anemofrigid cold: main manifestations is rare, the headache in vain of low voice speaking, the clear nasal mucus of sneeze, stream of nasal obstruction, cough, expectorant, dizziness, anorexia etc., is afraid of cold obvious, whole body is lossless and have the sensation of discomfort of aching, and does not generally generate heat, even if there is heating also lighter.Anemopyretic cold: main manifestations is the yellow sticky nasal mucus of stream, obviously, even have high heat, perspiration, throat pain, cough, expectorant Huang thick, tongue fur is BOHUANG color in heating.Summer-heat damp cold: main manifestations is heating, dizzy, distending pain, lassitude be with the disease such as uncomfortable in chest, nauseating from head to foot.Exterior cold and interior heat is caught a cold: have another name called " fire wrapped by cold ", and, headache sticky, irritated mainly with fever with aversion to cold, cough and asthma, expectorant Huang is primary symptom.For anemofrigid cold, with the diaphoretic medicine of pungent temperature with lung qi dispersing cold expelling, the pungent cool medicine that induces sweat should should be used, for the medicine that summer-heat damp cold then should induce sweat with clearing away summer-heat damp eliminating for anemopyretic cold.
Flu is a kind of common disease, flu about has 70% to be caused by infection virus, mainly contains influenza virus (first, second, third), parainfluenza virus, respiratory syncytial virus, adenovirus, rhinovirus, echovirus, Coxsackie virus, Measles virus, rubella virus.Generally within 1-3 days after being infected, just there will be nasal obstruction, sneeze, rhinorrhea, pharyngeal discomfort, tussicula, heating etc., temperature height differs.For the treatment of cat fever, mainly anti symptom treatment, advise medication after flu causes the rear body temperature of fever more than 38.5 DEG C, conventional Deere promise ibuprofen suspension, ibuprofen composition wherein has antipyretic effect, NSAID (non-steroidal anti-inflammatory drug), is cox-2 inhibitors, routine dose few side effects, for the symptom such as heating, headache, extremities aching pain, sneeze, rhinorrhea, nasal obstruction, pharyngalgia that relieve common colds and influenza cause.
Application publication number CN 102370810 A(application number 201110198814.7) Chinese patent literature disclose a kind of compound artemisia rupestris capsule and preparation method thereof.A kind of compound artemisia rupestris capsule described in this invention, is made up of following raw material of Chinese medicine: Herba Achilleae, Radix Isatidis, Folium Isatidis.Publication number CN 103316063A(application number 201210444851.6) Chinese patent literature disclose a kind of medical herbs moving back hyperpyrexia.Adult cold has a fever, and get fresh Herba Artemisiae Annuae 500g and press juice to drink, hyperpyrexia can be backed off.Child can take the circumstances into consideration increase and decrease according to age and body weight.Season autumn and winter two does not have Herba Artemisiae Annuae, and available embryo nelumbinis moves back hyperpyrexia.The Chinese patent literature of publication number CN 101411834A(application number 200810237655.5 discloses a kind of Chinese drugs agentia for the treatment of cat fever, consists of Radix Platycodonis, Rhizoma Coptidis, Radix Scutellariae, Semen Benincasae, Semen Coicis, Herba Houttuyniae, Semen Persicae, Radix Glycyrrhizae.
Traditional treatment mostly is Western medicine as aspirin, acetaminophen etc., and its treatment just sweating and heat resolving, antiviral, fundamentally can not remove interior-heat.It is relief of symptoms that simple Western medicine is brought down a fever, and does not fundamentally treat flu.It is cold for bringing down a fever by methods such as ethanol erasing whole bodies, sends an expedition against healthy energy, has used and had endless trouble.Abuse of antibiotics is brought down a fever, and is actually and destroys body immunity, makes immune system resist exopathogen, pathogenic QI in the body is deeply increased the weight of.Although surface symptoms temporary extinction, the not normal symptom of more serious viscera function must be there is soon.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine for the treatment of cat fever and preparation method thereof.The Chinese medicine curative effect for the treatment of cat fever provided by the invention soon, safely, have no side effect, treating both the principal and secondary aspects of a disease.
Technical scheme of the present invention is:
The Chinese medicine for the treatment of cat fever, takes off the primary raw material medicine stating weight proportion and is prepared from: Herba Alternantherae sessilis 15-30, Rhizoma Cynanchi Stauntonii 8-16, Radix Puerariae 15-20, Radix Sanguisorbae 9-15, Radix Cayratiae trifoliae 6-10, Radix Wikstroemae 5-12, Herba Agerati Conyzoidis 8-14, Herba Andrographis 9-15, Herb Pararuelliae delavayanae 4-8, Flos Lonicerae 10-20, Radix Peucedani turgeniifolii 6-9, Radix Glycyrrhizae 8-12.
The Chinese medicine for the treatment of cat fever, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Herba Alternantherae sessilis 19-25, Rhizoma Cynanchi Stauntonii 10-14, Radix Puerariae 16-19, Radix Sanguisorbae 10-13, Radix Cayratiae trifoliae 7-9, Radix Wikstroemae 7-10, Herba Agerati Conyzoidis 9-12, Herba Andrographis 10-13, Herb Pararuelliae delavayanae 5-7, Flos Lonicerae 14-18, Radix Peucedani turgeniifolii 6.5-8, Radix Glycyrrhizae 9-11.
The Chinese medicine for the treatment of cat fever, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Herba Alternantherae sessilis 22, Rhizoma Cynanchi Stauntonii 13, Radix Puerariae 17, Radix Sanguisorbae 11, Radix Cayratiae trifoliae 8, Radix Wikstroemae 9, Herba Agerati Conyzoidis 10, Herba Andrographis 11, Herb Pararuelliae delavayanae 6, Flos Lonicerae 16, Radix Peucedani turgeniifolii 7, Radix Glycyrrhizae 10.
Present invention also offers the preparation method Chinese medicine of aforementioned therapies cat fever being made pharmaceutically acceptable pill, thick paste agent, powder and decoction.
The preparation method of described pill is:
(1) first pot is burnt heat, sprinkle the rice soaked, make on its smooth pot, be heated to drop into Radix Wikstroemae when rice is smoldered, the weight of rice is the weight of the 1/3-1/2(preferably rice of Radix Wikstroemae weight is 2/5 of Radix Wikstroemae weight), stir gently, frying to rice is that coke yellow takes out, and removes rice, is cooled by Radix Wikstroemae, be ground into fine powder, cross 120-140 mesh sieve (preferred mistake 130 mesh sieve);
(2) Flos Lonicerae is ground into fine powder, crosses 120-140 mesh sieve (preferred mistake 130 mesh sieve);
(3) Radix Cayratiae trifoliae is put into marmite, add water, amount of water is 3-6 times (preferred amount of water is 4.5 times of Radix Cayratiae trifoliae weight) of Radix Cayratiae trifoliae weight, first decoct with high heat to boiling, after turn slow fire boiling 50-65 minute (preferably then turn slow fire boiling 55 minutes), leach medicinal liquid, leave standstill 7-9 hour (preferably leaving standstill 8 hours), obtain filtrate;
(4) all the other the 9 taste medical materials except Radix Wikstroemae, Radix Cayratiae trifoliae and Flos Lonicerae are ground to the powder altogether, cross 120-140 mesh sieve (preferred mistake 130 mesh sieve);
(5) step (1), step (2) and step (4) gained fine powder are fully mixed, with the general ball of step (3) gained filtrate, the weight of obtained every ball is the weight of the preferably obtained every ball of 0.15-0.4g(is 0.2g), dry at the temperature of 65-75 DEG C (preferably dry at the temperature of 68 DEG C), make pill water content control within 8%, to obtain final product.
The preparation method of described thick paste agent is:
(1) all the other except Flos Lonicerae 11 taste Chinese crude drug is poured in medicine pot shakeout, then soak 5-7 hour (preferably then soaking 6 hours), during light pressing material, water height drug plane is about 8-10 centimetre (preferably about 9 centimetres, water height drug plane during light pressing material);
(2) medical material step (1) soaked first decocts with high heat to boiling, after turn slow fire boiling 1.3-2.2 hour (preferably then turn slow fire boiling 1.8 hours), after leaching medicinal liquid, again add water to high drug plane to be about 6-8 centimetre (preferably again adding water to about 7 centimetres, high drug plane), continue to change slow fire boiling 1-1.6 hour into after intense fire decocts extremely boiling (preferably continuing to change slow fire boiling into 1.3 hours after intense fire decocts extremely boiling), add Flos Lonicerae, be fried boiling 15-25 minute (being preferably fried boiling 20 minutes), after while hot medicinal liquid being leached, medicinal residues double gauze is wrapped, strand is got it filled, and slag is interior remains medicinal liquid,
(3) merge three medicinal liquids, leave standstill after 7-10 hour and (preferably leave standstill after 9 hours), get supernatant heating and be condensed into the paste medicine (preferably get supernatant heating and be condensed into the paste medicine that relative density is 1.32) that relative density is 1.28-1.35;
(4) refined honey getting step (3) gained paste medicine 1.5-2.2 times amount joins (refined honey of excellent selecting step (3) gained paste medicine 2 times amount joins in paste medicine) in paste medicine, stir, be divided in the container of clean dried sterilizing, covered and enclosed after fully cooling.
The preparation method of described powder is:
(1) first pot is burnt heat, sprinkle the rice soaked, make on its smooth pot, be heated to drop into Radix Wikstroemae when rice is smoldered, the weight of rice is the weight of the 1/3-1/2(preferably rice of Radix Wikstroemae weight is 2/5 of Radix Wikstroemae weight), stir gently, frying to rice is that coke yellow takes out, remove rice, Radix Wikstroemae is cooled, be ground into fine powder;
(2) Radix Cayratiae trifoliae is put into marmite, add water, amount of water is 3.5-6.5 times (preferred amount of water is 5 times of Radix Cayratiae trifoliae weight) of Radix Cayratiae trifoliae weight, first decoct with high heat to boiling, after turn slow fire boiling 55-70 minute (preferably then turn slow fire boiling 60 minutes), leach medicinal liquid, leave standstill 7-9 hour (preferably leaving standstill 8 hours), get supernatant heating and be condensed into the paste medicine (preferably get supernatant heating and be condensed into the paste medicine that relative density is 1.35) that relative density is 1.32-1.38;
(3) by all the other the 10 taste medical materials pulverization respectively except Radix Wikstroemae and Radix Cayratiae trifoliae;
(4) add ethanol and step (2) gained paste medicine grinds altogether, then add step (1) and step (3) gained fine powder grinds well, be drying to obtain.
The preparation method of described decoction is:
(1) all the other except Flos Lonicerae 11 taste Chinese crude drug is poured in medicine pot shakeout, then soak 50-80 minute (preferably then soaking 65 minutes), during light pressing material, water height drug plane is about 1.8-2.5 centimetre (preferably about 2.3 centimetres, water height drug plane during light pressing material);
(2) medical material step (1) soaked first decocts with high heat to boiling, after turn slow fire boiling 30-45 minute (preferably then turn slow fire boiling 40 minutes), after leaching medicinal liquid, again add water to high drug plane to be about 0.8-1.5 centimetre (preferably again adding water to about 1.3 centimetres, high drug plane), continue to change slow fire boiling 20-30 minute into after intense fire decocts extremely boiling (preferably continuing to change slow fire boiling into 25 minutes after intense fire decocts extremely boiling), add Flos Lonicerae, be fried boiling 8-14 minute (being preferably fried boiling 12 minutes), after while hot medicinal liquid being leached, medicinal residues double gauze is wrapped, strand is got it filled, and slag is interior remains medicinal liquid,
(3) merge three medicinal liquids and get final product.
The Chinese medicine for the treatment of cat fever provided by the invention selects Chinese herbal medicine cheap and easy to get to be primary raw material, and compatibility is scientific and reasonable.In addition, excellent results of the present invention also shows:
1, induce sweat eliminating evil, allow pathogen exit body, then do not control and burn and burn from moving back, treating both the principal and the secondary aspects of a disease at the same time, therefore can speed more flu;
, have no side effect 2, safely;
3, there is heat-clearing and toxic substances removing, lower expectorant antitussive, expelling pathogenic factors from muscles for reducing heat, effects such as wind heat, dissipating blood stasis for subsidence of swelling, invigorating the spleen and replenishing QI of should faling apart,
For treatment cat fever Be very effective;
4, preparation method is simple, taking convenience.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Alternantherae sessilis: base is former: be the herb of amaranthaceous plant Alternanthera sessilis (L.) DC..The property of medicine: sweet, cold.GUIXIN, stomach, small intestine meridian.Function cures mainly: cool the blood dissipate blood stasis, heat-clearing and toxic substances removing, dehumidifies treating stranguria.Main hemoptysis, spit blood, have blood in stool, jaundice due to damp-heat, dysentery, has loose bowels, gingival swelling and pain, laryngopharynx swelling and pain, acute appendicitis, acute mastitis, the cheek of itching, swollen ulcer drug, eczema, stranguria, traumatic injury, venom.
Rhizoma Cynanchi Stauntonii: base is former: be the root and rhizome of asclepiadaceae plant rhizoma et radix cynanchi stauntoni or leaves of Daphne genkwa Rhizoma Cynanchi Stauntonii.Chemical analysis: containing triterpenoid saponin, extra large opium poppy glycoside unit A, B, extra large Semen Papaveris glycoside A and extra large Semen Papaveris glycoside unit C-Semen Thevetiae monosaccharide glycoside etc.Leaves of Daphne genkwa Rhizoma Cynanchi Stauntonii is containing triterpenoid saponin.The property of medicine: pungent, sweet, tepor.Return lung meridian.Function cures mainly: eliminating the pathogens from the lung sending down the abnormal ascending QI, lower expectorant antitussive.Control excess of the lung dyspnea with fullness of the chest, cough, excessive phlegm, gastralgia.
Radix Puerariae: base is former: be the dry root of legume pueraria lobata.Practise and claim Herba Gelsemii Elegantis.Dry.The property of medicine: sweet, pungent, cool.Return spleen, stomach warp.Function cures mainly: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels, hypertension neck pain.
Radix Sanguisorbae: base is former: be the root and rhizome of Flos Rosae Multiflorae kind of plant Radix Sanguisorbae.Chemical analysis: root contains tannin about 17%, triterpenoid saponin 2.5 ~ 4.0%.Isolated Saponin has: ziyu glycoside I, produces pomolic acid, arabinose and glucose after hydrolysis, ziyu glycoside II, and produce pomolic acid and arabinose after hydrolysis, ground Fructus Kaki Saponin B, Preliminary Identification is the triterpenoid saponin of glucuronic acid.Stem and leaf contains the glycoside of Quercetin and nimbecetin, the triterpene substances such as ursolic acid.Leaf is containing vitamin C.Flower is containing Chrysanthemin, the two glycoside pressure effect of Centaurea cyanus.The property of medicine: picric acid, cold.Return liver, large intestine channel.Function cures mainly: cooling blood for hemostasis, heat-clearing and toxic substances removing.Control haematemesis, epistaxis, dysentery, metrorrhagia, hemorrhoidal hamorrhage, anal fistula, carbuncle, eczema, incised wound, burn.
Radix Cayratiae trifoliae: base is former: be the root of vitaceae Caulis et Folium cayratiae trifoliae.The property of medicine: pungent, cool, poisonous.Return lung, spleen channel.Function cures mainly: heat-clearing and toxic substances removing.Main lung abscess, furuncle.
Radix Wikstroemae: base is former: be the stem and leaf of Isolated From Thymelaeaceae Species Radix Wikstroemae.The property of medicine: bitter, acrid, cold, poisonous.GUIXIN, lung, small intestine meridian.Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, pain relieving.Control scrofula, carbuncle, rheumatalgia, pertussis, traumatic injury.
Herba Agerati Conyzoidis: base is former: be the herb of Compositae Ageratum plant Ageratum conyzoides.Composition: herb is containing multiple flavone compound: Herba Agerati Conyzoidis flavone A, B, C, Nobiletin, senensetin, lindera pyrite B etc.Herb is also containing alkaloid: Lycopodium clavatum amine, and thorn insults standby potash and triterpenoid compound: freidelin, sterols: stigmasterol etc.Volatile oil: Herba Agerati Conyzoidis chromene, coumarin etc.Aerial parts contains plurality of color vinyl compound: 7-methoxyl group-2,2-dimethyl chromogen alkene, 7,8-dimethoxy-2,2-dimethyl chromogen alkene etc.The property of medicine: micro-hardship, pungent, cool.Return lung, pericardium channel.Function cures mainly: heat-clearing and toxic substances removing, hemostasis, pain relieving.Cure mainly cold, fever, laryngopharynx swelling and pain, aphtha of the mouth and tongue, spitting of blood, epistaxis, metrorrhagia, epigastric pain, rheumatic arthralgia, traumatic injury, traumatic hemorrhage, thrush, carbuncle furuncle, eczema pruritus.
Herba Andrographis: base is former: be herb or the leaf of acanthaceous plant Herba Andrographis.The property of medicine: " Quanzhou book on Chinese herbal medicine ": " bitter in the mouth, cold in nature, nontoxic." " Quanzhou book on Chinese herbal medicine ": " enter the heart, lung two warp." function cures mainly: heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.Control acute bacillary dysentery, gastroenteritis, flu, epidemic encephalitis, tracheitis, pneumonia, pertussis, pulmonary tuberculosis, lung abscess, cholecystitis, hypertension, epistaxis, oropharynx swells and ache, furuncle carbuncle, burn due to hot liquid or fire, venom.
Herb Pararuelliae delavayanae: base is former: be the herb of acanthaceous plant Herb Pararuelliae delavayanae.The property of medicine: mildly bitter flavor, pungent, cool in nature.Function cures mainly: heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.Main cough due to lung-heat, laryngopharynx swelling and pain, mumps, scrofula, carbuncle sore tumefacting virus, injury and bone fracture, trauma infection contamination.
Flos Lonicerae: base is former: be the alabastrum of caprifoliaceae plant Radix Ophiopogonis.Chemical analysis: flower is containing luteolin, inositol about 1% and Saponin, tannin etc.The property of medicine: sweet, cold.Attach to the lung and stomach meridians.Function cures mainly: heat clearing away, removing toxic substances.Control epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.
Radix Peucedani turgeniifolii: base is former: be the root of Umbelliferae Peucedanum plant Radix Peucedani turgeniifolii.Composition: herb, containing Coumarins, comprises Radix Peucedani turgeniifolii A prime, Radix Peucedani turgeniifolii B prime, Radix Peucedani turgeniifolii C prime, cis racemization triumphant promise lactone, the triumphant promise lactone of trans racemization etc.The property of medicine: cold nature, acrid in the mouth, hardship, nontoxic.Return lung, spleen ear two warp.Function cures mainly: wind heat of should faling apart, eliminating phlegm and relieving cough, the therapeutic method to keep the adverse QI flowing downwards.For cold anemopyretic, cough expectorant thick, dyspnea with fullness of the chest, headache and uncomfortable in chest.
Radix Glycyrrhizae: base is former: be the dry root and rhizome of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..The property of medicine: sweet, flat.GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of institute's abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
embodiment 1the Chinese medicine for the treatment of cat fever, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): Herba Alternantherae sessilis 15 parts, Rhizoma Cynanchi Stauntonii 8 parts, Radix Puerariae 15 parts, Radix Sanguisorbae 9 parts, Radix Cayratiae trifoliae 6 parts, Radix Wikstroemae 5 parts, Herba Agerati Conyzoidis 8 parts, Herba Andrographis 9 parts, Herb Pararuelliae delavayanae 4 parts, Flos Lonicerae 10 parts, Radix Peucedani turgeniifolii 6 parts, 8 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine decoction of above-mentioned treatment cat fever is:
(1) all the other except Flos Lonicerae 11 taste Chinese crude drug is poured in medicine pot shakeout, then soak 50 minutes, about 1.8 centimetres, water height drug plane during light pressing material;
(2) medical material step (1) soaked first decocts with high heat to boiling, after turn slow fire boiling 30 minutes, after leaching medicinal liquid, again add water to about 0.8 centimetre, high drug plane, continue to change slow fire boiling into 20 minutes after intense fire decocts extremely boiling, add Flos Lonicerae, be fried boiling 8 minutes, after being leached by medicinal liquid while hot, wrapped by medicinal residues double gauze, strand is got it filled, and slag is interior remains medicinal liquid;
(3) merge three medicinal liquids and get final product.
The present invention treats the using method of the Chinese medicine decoction of cat fever: oral, and every day twice, each 200mL(is warm).
embodiment 2the Chinese medicine for the treatment of cat fever, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): Herba Alternantherae sessilis 30 parts, Rhizoma Cynanchi Stauntonii 16 parts, Radix Puerariae 20 parts, Radix Sanguisorbae 15 parts, Radix Cayratiae trifoliae 10 parts, Radix Wikstroemae 12 parts, Herba Agerati Conyzoidis 14 parts, Herba Andrographis 15 parts, Herb Pararuelliae delavayanae 8 parts, Flos Lonicerae 20 parts, Radix Peucedani turgeniifolii 9 parts, 12 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine pill of above-mentioned treatment cat fever is:
(1) first pot is burnt heat, sprinkle the rice soaked, make on its smooth pot, be heated to drop into Radix Wikstroemae when rice is smoldered, the weight of rice is 2/5 of Radix Wikstroemae weight, stirs gently, and frying to rice is that coke yellow takes out, and removes rice, Radix Wikstroemae is cooled, is ground into fine powder, cross 130 mesh sieves;
(2) Flos Lonicerae is ground into fine powder, crosses 130 mesh sieves;
(3) Radix Cayratiae trifoliae is put into marmite, add water, amount of water is 4.5 times of Radix Cayratiae trifoliae weight, first decocts with high heat to boiling, after turn slow fire boiling 55 minutes, leach medicinal liquid, leave standstill 8 hours, obtain filtrate;
(4) all the other the 9 taste medical materials except Radix Wikstroemae, Radix Cayratiae trifoliae and Flos Lonicerae are ground to the powder altogether, cross 130 mesh sieves;
(5) step (1), step (2) and step (4) gained fine powder are fully mixed, with the general ball of step (3) gained filtrate, the weight of obtained every ball is 0.2g, dry at the temperature of 68 DEG C, makes pill water content control within 8%, to obtain final product.
model case one:liu XX, man, 28 years old.Main suit: cat fever is lossless, cough, appetite is poor, has tired sense of sleeping, infuses two days, without taking a turn for the better.Look into: T:38.9 DEG C.Take the Chinese medicine pill of the present embodiment gained treatment cat fever, oral, every day three times, each 20 balls.Take 1 day, burning is moved back.Take three days, all diseases disappear, recovery from illness.
embodiment 3the Chinese medicine for the treatment of cat fever, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): Herba Alternantherae sessilis 19 parts, Rhizoma Cynanchi Stauntonii 10 parts, Radix Puerariae 16 parts, Radix Sanguisorbae 10 parts, Radix Cayratiae trifoliae 7 parts, Radix Wikstroemae 7 parts, Herba Agerati Conyzoidis 9 parts, Herba Andrographis 10 parts, Herb Pararuelliae delavayanae 5 parts, Flos Lonicerae 14 parts, Radix Peucedani turgeniifolii 6.5 parts, 9 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine thick paste agent of above-mentioned treatment cat fever is:
(1) all the other except Flos Lonicerae 11 taste Chinese crude drug is poured in medicine pot shakeout, then soak 6 hours, about 9 centimetres, water height drug plane during light pressing material;
(2) medical material step (1) soaked first decocts with high heat to boiling, after turn slow fire boiling 1.8 hours, after leaching medicinal liquid, again add water to about 7 centimetres, high drug plane, continue to change slow fire boiling into 1.3 hours after intense fire decocts extremely boiling, add Flos Lonicerae, be fried boiling 20 minutes, after being leached by medicinal liquid while hot, wrapped by medicinal residues double gauze, strand is got it filled, and slag is interior remains medicinal liquid;
(3) merge three medicinal liquids, leave standstill after 9 hours, get supernatant heating and be condensed into the paste medicine that relative density is 1.32;
(4) refined honey getting step (3) gained paste medicine 2 times amount joins in paste medicine, stirs, is divided in the container of clean dried sterilizing, covered and enclosed after fully cooling.
model case two:woods XX, female, 34 years old.Main suit: headache, cold more than 2 days with it.Logical and the cold capsule of oral cold two days.Just have a fever again after alleviating drug withdrawal after taking medicine.Without nasal obstruction watery nasal discharge since morbidity, without cough medical history.Chest pain during air-breathing of having a medical check-up, night, body temperature was higher.To catch a cold before 4 days medical history.Body temperature 38.5 DEG C, blood pressure 120,80 millimetres of mercury.Tentative diagnosis is caught a cold.Take the Chinese medicine thick paste agent of the present embodiment gained treatment cat fever, oral, every day twice, each 15g.Take twice, temperature recovery is to normal value.Take 3 days, all diseases disappear, recovery from illness.
embodiment 4the Chinese medicine for the treatment of cat fever, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): Herba Alternantherae sessilis 25 parts, Rhizoma Cynanchi Stauntonii 14 parts, Radix Puerariae 19 parts, Radix Sanguisorbae 13 parts, Radix Cayratiae trifoliae 9 parts, Radix Wikstroemae 10 parts, Herba Agerati Conyzoidis 12 parts, Herba Andrographis 13 parts, Herb Pararuelliae delavayanae 7 parts, Flos Lonicerae 18 parts, Radix Peucedani turgeniifolii 8 parts, 11 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine powder of above-mentioned treatment cat fever is:
(1) first pot is burnt heat, sprinkle the rice soaked, make on its smooth pot, be heated to drop into Radix Wikstroemae when rice is smoldered, the weight of rice is 2/5 of Radix Wikstroemae weight, stirs gently, and frying to rice is that coke yellow takes out, and removes rice, is cooled by Radix Wikstroemae, be ground into fine powder;
(2) Radix Cayratiae trifoliae is put into marmite, add water, amount of water is 5 times of Radix Cayratiae trifoliae weight, first decoct with high heat to boiling, after turn slow fire boiling 60 minutes, leach medicinal liquid, leave standstill 8 hours, get supernatant heating and be condensed into the paste medicine that relative density is 1.35;
(3) by all the other the 10 taste medical materials pulverization respectively except Radix Wikstroemae and Radix Cayratiae trifoliae;
(4) add ethanol and step (2) gained paste medicine grinds altogether, then add step (1) and step (3) gained fine powder grinds well, be drying to obtain.
model case three: old XX, female, 48 years old.Main suit: cough, expectoration, high heat, weak 2 days.Have a medical check-up: god is clear, gas is slightly short, rhythm of the heart 95bpm, and rule is neat, body temperature 39.1 DEG C, blood pressure 110/70mmHg.Heart auscultation: two pulmonary respiration sounds are thick, not and obviously rale.Morbidity come stomach poor appetite, spirit not good enough, two just can, night sleep can.Diagnosis: acute upper respiratory tract infection.The traditional Chinese medical science is caught a cold.Take the Chinese medicine powder of the present embodiment gained treatment cat fever, every day twice, each 0.5g, boiled water is taken after mixing it with water.Take twice, body temperature is down to normal value.Take 4 days, all diseases disappear, recovery from illness.
embodiment 5the Chinese medicine for the treatment of cat fever, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): Herba Alternantherae sessilis 22 parts, Rhizoma Cynanchi Stauntonii 13 parts, Radix Puerariae 17 parts, Radix Sanguisorbae 11 parts, Radix Cayratiae trifoliae 8 parts, Radix Wikstroemae 9 parts, Herba Agerati Conyzoidis 10 parts, Herba Andrographis 11 parts, Herb Pararuelliae delavayanae 6 parts, Flos Lonicerae 16 parts, Radix Peucedani turgeniifolii 7 parts, 10 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine decoction of above-mentioned treatment cat fever is:
(1) all the other except Flos Lonicerae 11 taste Chinese crude drug is poured in medicine pot shakeout, then soak 65 minutes, about 2.3 centimetres, water height drug plane during light pressing material;
(2) medical material step (1) soaked first decocts with high heat to boiling, after turn slow fire boiling 40 minutes, after leaching medicinal liquid, again add water to about 1.3 centimetres, high drug plane, continue to change slow fire boiling into 25 minutes after intense fire decocts extremely boiling, add Flos Lonicerae, be fried boiling 12 minutes, after being leached by medicinal liquid while hot, wrapped by medicinal residues double gauze, strand is got it filled, and slag is interior remains medicinal liquid;
(3) merge three medicinal liquids and get final product.
test example:in order to verify the drug effect of the Chinese medicine decoction of embodiment 5 gained treatment cat fever, We conducted contrast test.In May ,-2011 in March, 2009, screen 258 routine cat fever patients in 8 hospitals, wherein male 100 example, women 158 example, age 15-60 year, 30.5 years old mean age, course of disease 1-5d, average course of disease 2.5d.Be divided into two groups at random, experimental group and matched group (often organizing 129 people).Experimental group male 49 example, women 80 example, age 15-60 year, 30.5 years old mean age, course of disease 1-5d, average course of disease 2.5d.Matched group male 51 example, women 78 example, age 15-60 year, 30.5 years old mean age, course of disease 1-5d, average course of disease 2.5d.Experimental group uses the present embodiment 5 products obtained therefrom, using method: oral, and every day twice, each 200mL(is warm).Matched group uses the medicine (as aspirin, GANMAOTONG sheet, LIUSHEN WAN etc.) of conventional therapy cat fever.Curative effect situation criterion: clinical recovery: within treatment 3d, temperature recovery is normal, and cold symptoms all disappears; Effective: within treatment 3d, body temperature is normal, the large all transference cures of flu; Take a turn for the better: within treatment 3d, body temperature reduces than before, the cardinal symptom partial disappearance of flu; Invalid: within treatment 3d, body temperature does not fall or raises, and the cardinal symptom of flu is without improvement.Wherein always effectively comprise clinical recovery and effective.Result is as shown in table 1.
Table 1 table 1: the Chinese medicine decoction compliance test result of embodiment 5 gained treatment cat fever
efficacy analysis:as can be seen from Table 1, use the clinical recovery rate of the experimental group of the Chinese medicine decoction of embodiment 5 gained treatment cat fever up to 80.62%, total effective rate reaches 98.45%, and uses the clinical recovery rate of conventional therapy cat fever medicine to only have 48.84%.Experiment shows, use the Chinese medicine decoction of embodiment 5 gained treatment cat fever compared with use other treatment cat fever medicine, its curative effect increases substantially, and cure rate significantly promotes, and inefficiency significantly reduces.
The present invention selects Herba Alternantherae sessilis, Rhizoma Cynanchi Stauntonii, Radix Puerariae and Radix Sanguisorbae etc. to carry out compatibility, makes the Chinese medicine for the treatment of cat fever.Herba Alternantherae sessilis cool the blood dissipate blood stasis in side, heat-clearing and toxic substances removing, dehumidifies treating stranguria.Rhizoma Cynanchi Stauntonii eliminating the pathogens from the lung sending down the abnormal ascending QI, lower expectorant antitussive.Radix Puerariae expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.Radix Sanguisorbae cooling blood for hemostasis, heat-clearing and toxic substances removing.Radix Cayratiae trifoliae heat-clearing and toxic substances removing.Radix Wikstroemae heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, pain relieving.Herba Agerati Conyzoidis heat-clearing and toxic substances removing, hemostasis, pain relieving.Herba Andrographis heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.Herb Pararuelliae delavayanae heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.Flos Lonicerae heat clearing away, removing toxic substances.Radix Peucedani turgeniifolii should fall apart wind heat, eliminating phlegm and relieving cough, the therapeutic method to keep the adverse QI flowing downwards.Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.All medicines share, and have heat-clearing and toxic substances removing, lower expectorant antitussive, expelling pathogenic factors from muscles for reducing heat, effects such as wind heat, dissipating blood stasis for subsidence of swelling, invigorating the spleen and replenishing QI of should faling apart, induce sweat eliminating evil, allow pathogen exit body, then do not control and burn and burn from moving back, treating both the principal and the secondary aspects of a disease at the same time, therefore can speed more flu.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. treat the Chinese medicine of cat fever, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Herba Alternantherae sessilis 15-30, Rhizoma Cynanchi Stauntonii 8-16, Radix Puerariae 15-20, Radix Sanguisorbae 9-15, Radix Cayratiae trifoliae 6-10, Radix Wikstroemae 5-12, Herba Agerati Conyzoidis 8-14, Herba Andrographis 9-15, Herb Pararuelliae delavayanae 4-8, Flos Lonicerae 10-20, Radix Peucedani turgeniifolii 6-9, Radix Glycyrrhizae 8-12.
2. the Chinese medicine for the treatment of cat fever as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Herba Alternantherae sessilis 19-25, Rhizoma Cynanchi Stauntonii 10-14, Radix Puerariae 16-19, Radix Sanguisorbae 10-13, Radix Cayratiae trifoliae 7-9, Radix Wikstroemae 7-10, Herba Agerati Conyzoidis 9-12, Herba Andrographis 10-13, Herb Pararuelliae delavayanae 5-7, Flos Lonicerae 14-18, Radix Peucedani turgeniifolii 6.5-8, Radix Glycyrrhizae 9-11.
3. the Chinese medicine for the treatment of cat fever as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Herba Alternantherae sessilis 22, Rhizoma Cynanchi Stauntonii 13, Radix Puerariae 17, Radix Sanguisorbae 11, Radix Cayratiae trifoliae 8, Radix Wikstroemae 9, Herba Agerati Conyzoidis 10, Herba Andrographis 11, Herb Pararuelliae delavayanae 6, Flos Lonicerae 16, Radix Peucedani turgeniifolii 7, Radix Glycyrrhizae 10.
4. the Chinese medicine of the treatment cat fever as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine of this treatment cat fever is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) first pot is burnt heat, sprinkle the rice soaked, make on its smooth pot, be heated to drop into Radix Wikstroemae when rice is smoldered, the weight of rice is the weight of the 1/3-1/2(preferably rice of Radix Wikstroemae weight is 2/5 of Radix Wikstroemae weight), stir gently, frying to rice is that coke yellow takes out, and removes rice, is cooled by Radix Wikstroemae, be ground into fine powder, cross 120-140 mesh sieve (preferred mistake 130 mesh sieve);
(2) Flos Lonicerae is ground into fine powder, crosses 120-140 mesh sieve (preferred mistake 130 mesh sieve);
(3) Radix Cayratiae trifoliae is put into marmite, add water, amount of water is 3-6 times (preferred amount of water is 4.5 times of Radix Cayratiae trifoliae weight) of Radix Cayratiae trifoliae weight, first decoct with high heat to boiling, after turn slow fire boiling 50-65 minute (preferably then turn slow fire boiling 55 minutes), leach medicinal liquid, leave standstill 7-9 hour (preferably leaving standstill 8 hours), obtain filtrate;
(4) all the other the 9 taste medical materials except Radix Wikstroemae, Radix Cayratiae trifoliae and Flos Lonicerae are ground to the powder altogether, cross 120-140 mesh sieve (preferred mistake 130 mesh sieve);
(5) step (1), step (2) and step (4) gained fine powder are fully mixed, with the general ball of step (3) gained filtrate, the weight of obtained every ball is the weight of the preferably obtained every ball of 0.15-0.4g(is 0.2g), dry at the temperature of 65-75 DEG C (preferably dry at the temperature of 68 DEG C), make pill water content control within 8%, to obtain final product.
5. the Chinese medicine of the treatment cat fever as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine of this treatment cat fever is made pharmaceutically acceptable thick paste agent, and the preparation method of described thick paste agent is:
(1) all the other except Flos Lonicerae 11 taste Chinese crude drug is poured in medicine pot shakeout, then soak 5-7 hour (preferably then soaking 6 hours), during light pressing material, water height drug plane is about 8-10 centimetre (preferably about 9 centimetres, water height drug plane during light pressing material);
(2) medical material step (1) soaked first decocts with high heat to boiling, after turn slow fire boiling 1.3-2.2 hour (preferably then turn slow fire boiling 1.8 hours), after leaching medicinal liquid, again add water to high drug plane to be about 6-8 centimetre (preferably again adding water to about 7 centimetres, high drug plane), continue to change slow fire boiling 1-1.6 hour into after intense fire decocts extremely boiling (preferably continuing to change slow fire boiling into 1.3 hours after intense fire decocts extremely boiling), add Flos Lonicerae, be fried boiling 15-25 minute (being preferably fried boiling 20 minutes), after while hot medicinal liquid being leached, medicinal residues double gauze is wrapped, strand is got it filled, and slag is interior remains medicinal liquid,
(3) merge three medicinal liquids, leave standstill after 7-10 hour and (preferably leave standstill after 9 hours), get supernatant heating and be condensed into the paste medicine (preferably get supernatant heating and be condensed into the paste medicine that relative density is 1.32) that relative density is 1.28-1.35;
(4) refined honey getting step (3) gained paste medicine 1.5-2.2 times amount joins (refined honey of excellent selecting step (3) gained paste medicine 2 times amount joins in paste medicine) in paste medicine, stir, be divided in the container of clean dried sterilizing, covered and enclosed after fully cooling.
6. the Chinese medicine of the treatment cat fever as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine of this treatment cat fever is made pharmaceutically acceptable powder, and the preparation method of described powder is:
(1) first pot is burnt heat, sprinkle the rice soaked, make on its smooth pot, be heated to drop into Radix Wikstroemae when rice is smoldered, the weight of rice is the weight of the 1/3-1/2(preferably rice of Radix Wikstroemae weight is 2/5 of Radix Wikstroemae weight), stir gently, frying to rice is that coke yellow takes out, remove rice, Radix Wikstroemae is cooled, be ground into fine powder;
(2) Radix Cayratiae trifoliae is put into marmite, add water, amount of water is 3.5-6.5 times (preferred amount of water is 5 times of Radix Cayratiae trifoliae weight) of Radix Cayratiae trifoliae weight, first decoct with high heat to boiling, after turn slow fire boiling 55-70 minute (preferably then turn slow fire boiling 60 minutes), leach medicinal liquid, leave standstill 7-9 hour (preferably leaving standstill 8 hours), get supernatant heating and be condensed into the paste medicine (preferably get supernatant heating and be condensed into the paste medicine that relative density is 1.35) that relative density is 1.32-1.38;
(3) by all the other the 10 taste medical materials pulverization respectively except Radix Wikstroemae and Radix Cayratiae trifoliae;
(4) add ethanol and step (2) gained paste medicine grinds altogether, then add step (1) and step (3) gained fine powder grinds well, be drying to obtain.
7. the Chinese medicine of the treatment cat fever as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine of this treatment cat fever is made pharmaceutically acceptable decoction, and the preparation method of described decoction is:
(1) poured in medicine pot by all the other except Flos Lonicerae 11 taste Chinese crude drug and shakeout, then soak 50-80 minute, during light pressing material, water height drug plane is about 1.8-2.5 centimetre;
(2) medical material step (1) soaked first decocts with high heat to boiling, after turn slow fire boiling 30-45 minute (preferably then turn slow fire boiling 40 minutes), after leaching medicinal liquid, again add water to high drug plane and be about 0.8-1.5 centimetre, continue to change slow fire boiling 20-30 minute into after intense fire decocts extremely boiling (preferably continuing to change slow fire boiling into 25 minutes after intense fire decocts extremely boiling), add Flos Lonicerae, be fried boiling 8-14 minute (being preferably fried boiling 12 minutes), after while hot medicinal liquid being leached, wrapped by medicinal residues double gauze, strand is got it filled, and slag is interior remains medicinal liquid;
(3) merge three medicinal liquids and get final product.
8. the preparation method of the Chinese medicine decoction for the treatment of cat fever as claimed in claim 7, it is characterized in that, then step soaks 65 minutes in (1).
9. the preparation method of the Chinese medicine decoction for the treatment of cat fever as claimed in claim 7, is characterized in that, about 2.3 centimetres, water height drug plane during light pressing material in step (1).
10. the preparation method of the Chinese medicine decoction for the treatment of cat fever as claimed in claim 7, is characterized in that, again add water to about 1.3 centimetres, high drug plane in step (2).
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