[go: up one dir, main page]

CN104435756A - Pharmaceutical composition capsule containing antrodia camphorata, and preparation method therefor - Google Patents

Pharmaceutical composition capsule containing antrodia camphorata, and preparation method therefor Download PDF

Info

Publication number
CN104435756A
CN104435756A CN201410671577.5A CN201410671577A CN104435756A CN 104435756 A CN104435756 A CN 104435756A CN 201410671577 A CN201410671577 A CN 201410671577A CN 104435756 A CN104435756 A CN 104435756A
Authority
CN
China
Prior art keywords
parts
radix
antrodia camphorata
capsule containing
composition capsule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410671577.5A
Other languages
Chinese (zh)
Inventor
陈财宝
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Liuzhou Tianzi Horticulture Co Ltd
Original Assignee
Liuzhou Tianzi Horticulture Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liuzhou Tianzi Horticulture Co Ltd filed Critical Liuzhou Tianzi Horticulture Co Ltd
Priority to CN201410671577.5A priority Critical patent/CN104435756A/en
Publication of CN104435756A publication Critical patent/CN104435756A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/342Adenophora
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/40Cornaceae (Dogwood family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/77Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965Asparagus, e.g. garden asparagus or asparagus fern
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a pharmaceutical composition capsule containing antrodia camphorata. The pharmaceutical composition capsule containing the antrodia camphorata includes the following components according to parts by weight: 30 to 50 parts of the antrodia camphorata, 30 to 40 parts of adenophora stricta, 28 to 32 parts of radix polygonati officinalis, 25 to 30 parts of radix asparagi, 22 to 26 parts of dendrobium nobile, 20 to 25 parts of Chinese wolfberry fruits, 15 to 20 parts of prepared radix rehmanniae, 12 to 18 parts of dogwood, 10 to 15 parts of moutan barks, 10 to 12 parts of Chinese yams, 8 to 12 parts of poria cocos, 8 to 10 parts of rhizoma alismatis, 6 to 9 parts of bighead atractylodes rhizome, 6 to 9 parts of arillus longan, 3 to 5 parts of Chinese angelica, 3 to 5 parts of ophiopogon roots, 2 to 4 parts of polygonum multiflorum, 1 to 2 parts of cortex cinnamomi, and 1 to 2 parts of radix aconiti carmichaeli. The invention further provides a preparation method for the pharmaceutical composition capsule containing the antrodia camphorata. The pharmaceutical composition capsule containing the antrodia camphorata and the preparation method therefor, provided by the invention, have the following benefits: the preparation is easy to operate; the pharmaceutical effect can be exerted to the largest extent; experiments show that the prepared pharmaceutical composition capsule containing the antrodia camphorata can effectively inhibit the scattering of cancer cells, so as to greatly improve the survival rate of a cancer patient, and enhance the body immunity of the patient.

Description

A kind of medicament composition capsule containing Antrodia Camphorata and preparation method thereof
Technical field
The present invention relates to a kind of medicament composition capsule containing Antrodia Camphorata and preparation method thereof.
Background technology
Antrodia Camphorata has another name called Antrodia camphorata, and belong to Aphyllophorales, Polyporaceae, Antrodia genus, perennial mushroom fungus class, Latin is called Antrodia camphorata, is the novel species just delivered by biochemical boundary nineteen ninety.Its growth district is between the height above sea level 450-2000 rice mountain forest of mountain area, Taiwan, the heartwood inwall that only the Cinnamomum kanahirai hay tree trunk of growth more than the peculiar a century in Taiwan is rotten, or the Cinnamomum kanahirai hay trees material moist surface of withered lodging, because it gathers not easily, add that wild Cinnamomum kanahirai hay wood is classified as national treasure level by government in recent years one of biological, also therefore illegal mining Antrodia Camphorata social events still time have what is heard.
Antrodia Camphorata except be used to prevention, treatment tumor and cancerous cell diffusion, transfer while, cancer ascites can also be eliminated, severe pain, the inappetence common to cancer sufferer in latter stage, and radiotherapy, chemotherapy side effect etc., there is the improvement effect quite shown, many cancer interviewees also represent, oneself life quality after stock cattle Antrodia camphorata obtains and significantly improves, and thus daily life gradually recovers normal.β-D-glucan(callose in Antrodia camphorata polysaccharides) there is anticancer effect, add its a large amount of triterpenoid compound composition, can anticancer effect be increased.The experiment of the large institute of platform confirms that it can suppress liver cancer cell growth.Except preventing, treat the diffusion of tumor and cancerous cell, transfer, Antrodia Camphorata can also eliminate cancer ascites, for cancer sufferer in latter stage common have an intense pain, inappetence etc., more have quite significant improvement result.
Summary of the invention
Object of the present invention is exactly for above-mentioned defect of the prior art, provides a kind of medicament composition capsule containing Antrodia Camphorata.
To achieve these goals, technical scheme provided by the invention is: a kind of medicament composition capsule containing Antrodia Camphorata, be made up of the following component according to parts by weight: Antrodia Camphorata 30-50 part, Radix Adenophorae (Radix Glehniae) 30-40 part, Rhizoma Polygonati Odorati 28-32 part, Radix Asparagi 25-30 part, Herba Dendrobii 22-26 part, Fructus Lycii 20-25 part, Radix Rehmanniae Preparata 15-20 part, Fructus Corni 12-18 part, Cortex Moutan 10-15 part, Rhizoma Dioscoreae 10-12 part, Poria 8-12 part, Rhizoma Alismatis 8-10 part, Rhizoma Atractylodis Macrocephalae 6-9 part, Arillus Longan 6-9 part, Radix Angelicae Sinensis 3-5 part, Radix Ophiopogonis 3-5 part, Radix Polygoni Multiflori 2-4 part, Cortex Cinnamomi 1-2 part, Radix Aconiti Lateralis Preparata 1-2 part.
Further, above-mentioned a kind of medicament composition capsule containing Antrodia Camphorata, is made up of the following component according to parts by weight: Antrodia Camphorata 40 parts, Radix Adenophorae (Radix Glehniae) 35 parts, Rhizoma Polygonati Odorati 30 parts, Radix Asparagi 28 parts, Herba Dendrobii 24 parts, Fructus Lycii 23 parts, Radix Rehmanniae Preparata 18 parts, Fructus Corni 16 parts, Cortex Moutan 12 parts, Rhizoma Dioscoreae 11 parts, 10 parts, Poria, Rhizoma Alismatis 9 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, Arillus Longan 8 parts, Radix Angelicae Sinensis 4 parts, Radix Ophiopogonis 4 parts, Radix Polygoni Multiflori 3 parts, Cortex Cinnamomi 2 parts, Radix Aconiti Lateralis Preparata 2 parts.
Second object of the present invention there is provided the preparation method of above-mentioned a kind of medicament composition capsule containing Antrodia Camphorata, comprises the following steps:
1) each drug component according to said ratio is taken;
2) Antrodia Camphorata of the formula ratio in step 1) is crushed to 80 orders, after mixing with Radix Adenophorae (Radix Glehniae), Radix Rehmanniae Preparata, Poria, Rhizoma Alismatis, Arillus Longan, Radix Ophiopogonis, Radix Polygoni Multiflori and Radix Aconiti Lateralis Preparata, add water soaking steaming and decocting after 20 minutes, amount of water is 2 times of said medicine component weight, steaming and decocting totally three times, respectively with slow fire, each steaming and decocting of intense fire 30 minutes, 3 medicinal liquids obtained merge, and obtain constituent part medicinal liquid;
3) by step 2) the constituent part medicinal liquid that obtains, be placed in room temperature environment to cool, add all the other components of formula ratio in step 1) again, soak after 20 minutes, fill into the water of gross mass 1 times, steaming and decocting again, steaming and decocting totally three times, respectively with slow fire, each steaming and decocting of intense fire 30 minutes, 3 medicinal liquids obtained merge, and obtain compositions medicinal liquid;
4) compositions medicinal liquid vacuum lyophilization step 3) obtained, obtains composition freeze-dried powder, and through the medicament composition capsule obtaining Antrodia Camphorata of granulating, vacuum lyophilization temperature is-20 DEG C ~-30 DEG C, and vacuum is 8-10 handkerchief.
Beneficial effect of the present invention is: a kind of medicament composition capsule containing Antrodia Camphorata provided by the invention and preparation method thereof, preparation manipulation is simple, drug effect can be played to greatest extent, the experiment proved that, prepare compared with can the diffusion of effective anticancer, greatly extend the survival rate of cancer patient, improve sufferer immunity of organisms.
Detailed description of the invention
embodiment 1:
A preparation method for medicament composition capsule containing Antrodia Camphorata, comprises the following steps:
1) the following drug component according to parts by weight is taken: Antrodia Camphorata 30-50 part, Radix Adenophorae (Radix Glehniae) 30-40 part, Rhizoma Polygonati Odorati 28-32 part, Radix Asparagi 25-30 part, Herba Dendrobii 22-26 part, Fructus Lycii 20-25 part, Radix Rehmanniae Preparata 15-20 part, Fructus Corni 12-18 part, Cortex Moutan 10-15 part, Rhizoma Dioscoreae 10-12 part, Poria 8-12 part, Rhizoma Alismatis 8-10 part, Rhizoma Atractylodis Macrocephalae 6-9 part, Arillus Longan 6-9 part, Radix Angelicae Sinensis 3-5 part, Radix Ophiopogonis 3-5 part, Radix Polygoni Multiflori 2-4 part, Cortex Cinnamomi 1-2 part, Radix Aconiti Lateralis Preparata 1-2 part;
2) Antrodia Camphorata of the formula ratio in step 1) is crushed to 80 orders, after mixing with Radix Adenophorae (Radix Glehniae), Radix Rehmanniae Preparata, Poria, Rhizoma Alismatis, Arillus Longan, Radix Ophiopogonis, Radix Polygoni Multiflori and Radix Aconiti Lateralis Preparata, add water soaking steaming and decocting after 20 minutes, amount of water is 2 times of said medicine component weight, steaming and decocting totally three times, respectively with slow fire, each steaming and decocting of intense fire 30 minutes, 3 medicinal liquids obtained merge, and obtain constituent part medicinal liquid;
3) by step 2) the constituent part medicinal liquid that obtains, be placed in room temperature environment to cool, add all the other components of formula ratio in step 1) again, soak after 20 minutes, fill into the water of gross mass 1 times, steaming and decocting again, steaming and decocting totally three times, respectively with slow fire, each steaming and decocting of intense fire 30 minutes, 3 medicinal liquids obtained merge, and obtain compositions medicinal liquid;
4) compositions medicinal liquid vacuum lyophilization step 3) obtained, obtains composition freeze-dried powder, and through the medicament composition capsule obtaining Antrodia Camphorata of granulating, vacuum lyophilization temperature is-20 DEG C ~-30 DEG C, and vacuum is 8-10 handkerchief.
embodiment 2:
A preparation method for medicament composition capsule containing Antrodia Camphorata, comprises the following steps:
1) the following drug component according to parts by weight is taken: Antrodia Camphorata 40 parts, Radix Adenophorae (Radix Glehniae) 35 parts, Rhizoma Polygonati Odorati 30 parts, Radix Asparagi 28 parts, Herba Dendrobii 24 parts, Fructus Lycii 23 parts, Radix Rehmanniae Preparata 18 parts, Fructus Corni 16 parts, Cortex Moutan 12 parts, Rhizoma Dioscoreae 11 parts, 10 parts, Poria, Rhizoma Alismatis 9 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, Arillus Longan 8 parts, Radix Angelicae Sinensis 4 parts, Radix Ophiopogonis 4 parts, Radix Polygoni Multiflori 3 parts, Cortex Cinnamomi 2 parts, Radix Aconiti Lateralis Preparata 2 parts;
2) Antrodia Camphorata of the formula ratio in step 1) is crushed to 80 orders, after mixing with Radix Adenophorae (Radix Glehniae), Radix Rehmanniae Preparata, Poria, Rhizoma Alismatis, Arillus Longan, Radix Ophiopogonis, Radix Polygoni Multiflori and Radix Aconiti Lateralis Preparata, add water soaking steaming and decocting after 20 minutes, amount of water is 2 times of said medicine component weight, steaming and decocting totally three times, respectively with slow fire, each steaming and decocting of intense fire 30 minutes, 3 medicinal liquids obtained merge, and obtain constituent part medicinal liquid;
3) by step 2) the constituent part medicinal liquid that obtains, be placed in room temperature environment to cool, add all the other components of formula ratio in step 1) again, soak after 20 minutes, fill into the water of gross mass 1 times, steaming and decocting again, steaming and decocting totally three times, respectively with slow fire, each steaming and decocting of intense fire 30 minutes, 3 medicinal liquids obtained merge, and obtain compositions medicinal liquid;
4) compositions medicinal liquid vacuum lyophilization step 3) obtained, obtains composition freeze-dried powder, and through the medicament composition capsule obtaining Antrodia Camphorata of granulating, vacuum lyophilization temperature is-20 DEG C ~-30 DEG C, and vacuum is 8-10 handkerchief.
Last it is noted that the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (3)

1. the medicament composition capsule containing Antrodia Camphorata, it is characterized in that, be made up of the following component according to parts by weight: Antrodia Camphorata 30-50 part, Radix Adenophorae (Radix Glehniae) 30-40 part, Rhizoma Polygonati Odorati 28-32 part, Radix Asparagi 25-30 part, Herba Dendrobii 22-26 part, Fructus Lycii 20-25 part, Radix Rehmanniae Preparata 15-20 part, Fructus Corni 12-18 part, Cortex Moutan 10-15 part, Rhizoma Dioscoreae 10-12 part, Poria 8-12 part, Rhizoma Alismatis 8-10 part, Rhizoma Atractylodis Macrocephalae 6-9 part, Arillus Longan 6-9 part, Radix Angelicae Sinensis 3-5 part, Radix Ophiopogonis 3-5 part, Radix Polygoni Multiflori 2-4 part, Cortex Cinnamomi 1-2 part, Radix Aconiti Lateralis Preparata 1-2 part.
2. a kind of medicament composition capsule containing Antrodia Camphorata according to claim 1, it is characterized in that, be made up of the following component according to parts by weight: Antrodia Camphorata 40 parts, Radix Adenophorae (Radix Glehniae) 35 parts, Rhizoma Polygonati Odorati 30 parts, Radix Asparagi 28 parts, Herba Dendrobii 24 parts, Fructus Lycii 23 parts, Radix Rehmanniae Preparata 18 parts, Fructus Corni 16 parts, Cortex Moutan 12 parts, Rhizoma Dioscoreae 11 parts, 10 parts, Poria, Rhizoma Alismatis 9 parts, the Rhizoma Atractylodis Macrocephalae 8 parts, Arillus Longan 8 parts, Radix Angelicae Sinensis 4 parts, Radix Ophiopogonis 4 parts, Radix Polygoni Multiflori 3 parts, Cortex Cinnamomi 2 parts, Radix Aconiti Lateralis Preparata 2 parts.
3. the preparation method of a kind of medicament composition capsule containing Antrodia Camphorata according to claim 1 and 2, is characterized in that, comprise the following steps:
1) each drug component according to proportioning described in claim 1 or 2 is taken;
2) Antrodia Camphorata of the formula ratio in step 1) is crushed to 80 orders, after mixing with Radix Adenophorae (Radix Glehniae), Radix Rehmanniae Preparata, Poria, Rhizoma Alismatis, Arillus Longan, Radix Ophiopogonis, Radix Polygoni Multiflori and Radix Aconiti Lateralis Preparata, add water soaking steaming and decocting after 20 minutes, amount of water is 2 times of said medicine component weight, steaming and decocting totally three times, respectively with slow fire, each steaming and decocting of intense fire 30 minutes, 3 medicinal liquids obtained merge, and obtain constituent part medicinal liquid;
3) by step 2) the constituent part medicinal liquid that obtains, be placed in room temperature environment to cool, add all the other components of formula ratio in step 1) again, soak after 20 minutes, fill into the water of gross mass 1 times, steaming and decocting again, steaming and decocting totally three times, respectively with slow fire, each steaming and decocting of intense fire 30 minutes, 3 medicinal liquids obtained merge, and obtain compositions medicinal liquid;
4) compositions medicinal liquid vacuum lyophilization step 3) obtained, obtains composition freeze-dried powder, and through the medicament composition capsule obtaining Antrodia Camphorata of granulating, vacuum lyophilization temperature is-20 DEG C ~-30 DEG C, and vacuum is 8-10 handkerchief.
CN201410671577.5A 2014-11-21 2014-11-21 Pharmaceutical composition capsule containing antrodia camphorata, and preparation method therefor Pending CN104435756A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410671577.5A CN104435756A (en) 2014-11-21 2014-11-21 Pharmaceutical composition capsule containing antrodia camphorata, and preparation method therefor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410671577.5A CN104435756A (en) 2014-11-21 2014-11-21 Pharmaceutical composition capsule containing antrodia camphorata, and preparation method therefor

Publications (1)

Publication Number Publication Date
CN104435756A true CN104435756A (en) 2015-03-25

Family

ID=52883017

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410671577.5A Pending CN104435756A (en) 2014-11-21 2014-11-21 Pharmaceutical composition capsule containing antrodia camphorata, and preparation method therefor

Country Status (1)

Country Link
CN (1) CN104435756A (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1799560A (en) * 2005-09-28 2006-07-12 莱阳农学院 Liver cancer resistant Antrodia camphorata and preparation method thererof
CN101380346A (en) * 2008-10-10 2009-03-11 深圳市中科海外科技有限公司 Traditional Chinese composition for treating tumor and production method thereof
CN104116762A (en) * 2013-04-25 2014-10-29 中一师生物科技股份有限公司 Compound formula of Antrodia cintrodia and medicinal composition containing the compound formula of Antrodia cintrodia

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1799560A (en) * 2005-09-28 2006-07-12 莱阳农学院 Liver cancer resistant Antrodia camphorata and preparation method thererof
CN101380346A (en) * 2008-10-10 2009-03-11 深圳市中科海外科技有限公司 Traditional Chinese composition for treating tumor and production method thereof
CN104116762A (en) * 2013-04-25 2014-10-29 中一师生物科技股份有限公司 Compound formula of Antrodia cintrodia and medicinal composition containing the compound formula of Antrodia cintrodia

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
听海: ""牛樟芝的抗癌效果"", 《HTTP://WWW.ZJKANGAI.COM/JLNIUZHANGZHI/201210231899656.SHTML》 *
尤民生主编: "《提高农业综合生产能力的理论与实践》", 30 September 2005, 海风出版社 *
张毅红等: ""樟芝抗癌作用的研究进展"", 《肿瘤预防与治疗》 *
徐光星等: ""辨证治癌 扶正为先——何任治疗癌症学术经验探究(上)"", 《浙江中医杂志》 *
陈熠主编: "《肿瘤中医证治精要》", 31 August 2007, 上海科学技术出版社 *

Similar Documents

Publication Publication Date Title
CN101381668B (en) Method for preparing health-care medicinal liquor
CN103393599B (en) Preparation method of traditional Chinese medicine fine powder
WO2017181988A1 (en) Traditional-chinese-medicine composition effective in treating various conditions, and derivative thereof and product thereof
CN102911847B (en) Skin-caring nutritious wine
CN1276216A (en) Process for preparing non-decoction Chinese medicine
CN101983703B (en) Traditional Chinese medicine composition and traditional Chinese medicine preparation
CN104171204A (en) Tea for alleviating colorectal cancer
CN102670666A (en) Preparation method of finest traditional Chinese medicine powder
CN103432339B (en) A kind of Chinese medicine composition and Chinese medicine preparation and uses thereof
CN105998652A (en) Traditional Chinese medicine composition and application and preparation thereof
CN1970063A (en) Tincture series for treating cancer
CN110075247A (en) A kind of herbal mixture fermentation liquid and preparation method thereof
CN104435756A (en) Pharmaceutical composition capsule containing antrodia camphorata, and preparation method therefor
CN104547543A (en) Traditional Chinese medicine composition for treating anemia
CN105273943A (en) Liver-protecting healthcare liquor and preparation method thereof
CN104435755A (en) Preparation method for pharmaceutical composition capsule containing antrodia camphorata
CN104398843A (en) Yam-containing antrodia camphorate medicinal composition capsule
CN102974124B (en) Application of reduced pressure reflux technology in traditional Chinese medicine extraction
CN104474182A (en) Antrodia and tea composition
CN104491465A (en) Pharmaceutical composition capsule containing Antrodia camphorat
CN104398846A (en) Polygonum multiflorum-containing antrodia camphorate medicinal composition capsule
CN104491467A (en) Angelica sinensis-containing antrodia camphorata pharmaceutical composition capsules
CN104491468A (en) Radix ophiopogonis-containing antrodia camphorata pharmaceutical composition capsules
CN104491469A (en) Longan aril-containing antrodia camphorata pharmaceutical composition capsules
CN104398845A (en) Atractylodes-containing antrodia camphorate medicinal composition capsule

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20150325