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CN104434034A - Hand-held near-infrared wound detection device for cephalophyma - Google Patents

Hand-held near-infrared wound detection device for cephalophyma Download PDF

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Publication number
CN104434034A
CN104434034A CN201410717848.6A CN201410717848A CN104434034A CN 104434034 A CN104434034 A CN 104434034A CN 201410717848 A CN201410717848 A CN 201410717848A CN 104434034 A CN104434034 A CN 104434034A
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probe
light source
mount pad
detector
circuit board
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CN201410717848.6A
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CN104434034B (en
Inventor
张彦军
孙秋明
马军
孙景工
高万玉
胡名玺
王济虎
田涛
孙晓军
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Institute of Medical Equipment Chinese Academy of Military Medical Sciences
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Institute of Medical Equipment Chinese Academy of Military Medical Sciences
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04Constructional details of apparatus
    • A61B2560/0406Constructional details of apparatus specially shaped apparatus housings
    • A61B2560/0425Ergonomically shaped housings

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The invention discloses a hand-held type near-infrared wound detection device for cephalophyma. The device comprises a detecting instrument body containing both a light source probe and a detector probe, and the device further comprises a lens hood capable of moving in a sliding guide column which is at the lower part of the detecting instrument body direction, so that the lens hood covers the light source probe and the detector probe during detection so as to be in contact with a curved surface at the head to form a darkroom. The light source probe and the detector probe used in the detection device are elastic probe mechanisms, the mechanisms comprise shielding hoods, mounting seats, springs, conical seats and fiber optic probes, the mechanisms have independent elastic capacities of moving up and down in use and can be suitable for different curved surfaces of the head. For the device disclosed by the invention, a light source module, a detector module, coupling of an optical fiber/a light source and filtering and the coupling of the optical fiber/a detector are also integrated, so that the consumptive materials are low in cost and convenient to replace.

Description

Device is hindered in the inspection of a kind of hand-held Near-infrared Brain hematoma
Technical field
The invention belongs to Photobiology sniffer, relate to the inspection of a kind of hand-held Near-infrared Brain hematoma and hinder device.
Background technology
On-the-spot in the war such as wartime, training, accident, disaster, inevitably exist due to blast, fall and the mechanics factor such as impact, act on human brain and form bleeding due to trauma, cause forming fatal intracranial hematoma.According to statistics, dead in war soldier has nearly 50% to be because head injuries caused.And at ordinary times, the craniocerebral injury caused because of accident, traffic accident, disaster has become and accounts for second cause the dead cause of disease after tumor, cardiovascular and cerebrovascular disease.
The treatment key of traumatic cerebral hematoma is promptly and accurately to detect, suit the medicine to the illness dispose and fast after give.Especially the prime time section of l hour after wound.But, owing to lacking the objective reliable detection cephalophyma means that can carry out at the scene, can not give treatment to the cephalophyma wounded targetedly and after give, make many wounded lose best treatment opportunity.
At present, that can carry out accurately detecting to cephalophyma is computed tomography (CT), is called as " goldstandard " of diagnosis of intracranial hematoma.But, CT apparatus expensive and be difficult to before institute on-the-spot, and its in rural area, community, little medical institutions from far-off regions also do not popularize, use and be very limited; In addition, CT be not suitable for continuous detecting is carried out to wounded's cerebral hemorrhage situation.In addition, can not detect the frequent of bleeding after the irremovable wounded, Delayed onset cerebral hemorrhage and cerebral operations.Therefore, a kind of Medical Instruments of portable, sustainable detection cephalophyma is needed.
At present, can the tissue such as transdermal, skull and sensitivity principle to intracranial hemorrhage thereof easily based near infrared light, there is the portable brain hematoma detecting instrument adopting near infrared detection Technology design.
American documentation literature US8060189 discloses a kind of Near-infrared Brain hematoma detection system, and its commercially produced product is respectively Inftrascanner1000/2000 type cephalophyma scanner.Wherein 1000 types are split-type design, and be made up of detector and PDA, both are connected by bluetooth.2000 types are a new generation's equipment, for integral type designs.The base of detector is provided with near-infrared light source, near infrared detector and fibre-optical probe, but two fibre-optical probe can not self-movement, or fibre-optical probe is fixed on the larger probe cover of a volume, two probes are nonelastic, can not be applicable to the curved surface 3D shape of human body head, uncontrollable measurement dynamics, causes the increase of measurement error, there is the waste that the probe cover entirety high with cost is abandoned during replacing, and carrying amount is limited; No matter be 1000 types or 2000 types, all design without reliable shading, cannot shield and huge external environment light is affected on measurement result, cause measurement error under outdoor or indoor strong ambient light to increase.Infrascanner Model 1000 major parameter (from FDA authentication document) commercial is at present: fathom: 3.5cm under epidermis; Minimum detectable range measures amount of bleeding 3.5ml; Detection sensitivity 88%, specificity 90.7%; Detection time 3min.
Summary of the invention
For solving the problem, the object of the present invention is to provide and a kind ofly can be characterized in portable before institute and the handheld apparatus of the on-the-spot quick inspection wound without realizing under CT condition wounded's cephalophyma of war, noinvasive, fast, accurate and without any need for reagent.
The present invention is by the following technical solutions:
Device is hindered in the inspection of a kind of hand-held Near-infrared Brain hematoma, comprise the detector body containing light source probe and detector probe, also comprise a shade, wherein, described detector body lower part establishes slide-and-guide post, and shade, by the molding of dark shading soft material, is the cover body to lower open mouth, this is external to be sleeved on detector, and shade inside upper part is provided with the sliding surface matched with slide-and-guide post shapes and size makes shade and detector body realize relative motion to be socketed slide-and-guide post.
The above device, the hollow housing of detector body exterior for ease of gripping, the slide-and-guide post outside dimensions of lower housing section certain length is slightly less than housing epimere peripheral dimension, moves distance to limit on shade; Housing lowermost end is provided with base, and base dimensions moves down size slightly larger than the peripheral dimension of slide-and-guide post with what limit shade; Base is equipped with the light source probe and detector probe that stretch out downwards.
In described device, shade is along when moving up and down in lead movable distance, the Design of length of shade is: make not block light source probe and detector probe during its top at slide-and-guide post, move it simultaneously to slide-and-guide post bottom time well beyond two probes, and darkroom can be formed with head curved face contact.
In described device, detector body interior is equipped with perpendicular to two pieces of base parallel control circuit boards and left control circuit board and right control circuit board, and the battery bin of battery is housed, and battery the two poles of the earth are connected into control circuit board; Light source probe is connected and the downward protuberate basic unit of probe tip with base with detector probe distribution.
In described device, the epimere of left control circuit board, right control circuit board, battery bin and light source probe and detector probe is all closed in the space that housing and base surround, between light source probe and detector probe two tip, optimal distance is 3-5cm, and battery, circuit board and probe epimere are electrically connected.
In described device, described light source probe and detector probe are spring probe mechanism; This spring probe mechanism includes radome, mount pad, spring and conical seat and fibre-optical probe, wherein:
Radome is the cylindrical cavity of band side open surface, and through hole is offered for drawing the electricity supply and control line of the photoelectric cell installed in mount pad in its upper end, and lower end establishes the end of evagination in order to fix with base, and radome bottom and base relative position are equipped with opening;
Mount pad is step-like hollow posts, axially be sleeved on the interior also bottom of cavity of radome through base, mount pad is provided with step convex tendon, and its maximum outside diameter is equal with radome internal diameter, and bottom minimum outer diameter is equal to the opening of base to enable mount pad be fixedly mounted on base;
Mount pad upper end has two certain length elongated holes relatively, and its step convex tendon top is provided with step, sheathed spring on step, and the bottom of spring props up mount pad design step convex tendon, and its drift is greater than elongated hole length;
Conical seat is fixedly mounted on the bottom of mount pad, and it has longitudinal installing hole;
Fibre-optical probe interts in fibre-optical probe installing hole, is arranged on the bottom at mount pad.
In described device, mount pad is the step-like hollow posts that downward size reduces, axially be sleeved on the interior also bottom of cavity of radome through the opening of base, mount pad design step convex tendon, its maximum outside diameter is equal with radome internal diameter, bottom minimum outer diameter is equal with the opening of base, to be fixedly mounted on base by mount pad;
Mount pad has the elongated hole that two longitudinal directions have certain length relatively in upper end, its step convex tendon top is provided with step, sheathed spring on step, and the bottom of spring props up mount pad design step convex tendon, and its drift higher than elongated hole bottom, the relevant position of radome also has screw, spring bottom props up the step convex tendon of mount pad, during installation with instrument or hands temporarily by spring top compression to mount pad elongated hole topmost below, and the space of screw screw-in can be reserved, the screw that can stretch into elongated hole 2-4mm by length screws in mount pad elongated hole from radome screw, the height of radome screw is original design just in time make screw screw in after be positioned at the elongated hole of mount pad topmost, pressuring spring makes spring have certain pre-elasticity by screw, there is a displacement to realize mount pad between mount pad top and the top of radome and flexibly move up and down certain distance.
In described device, for light source probe is installed mount pad in be equiped with LD light source module and collimating lens from top to bottom, the distance of collimating lens and LD light source module lower end is 1-4mm; Or, for detector probe is installed mount pad in be equipped with precise light electric diode and optical filter from top to bottom, upper end and the optical filter of fibre-optical probe are close to installation.
In described device, the inner longitudinal hole of described conical seat is fibre-optical probe installing hole, establishes the centre bore of two laterally inwardly convergents, install steel ball, spring and jackscrew from the inside to the outside respectively in centre bore in its cylinder partial bottom;
Described fibre-optical probe consists of an entirety by fibre-optical probe seat, optical fiber protective tube and optical fiber, and optical fiber is arranged in optical fiber protective tube, and optical fiber front end is hemisphere face and stretches out optical fiber protective tube slightly forward, and fiber termination box optical fiber protective tube is fixed in fiber bench.
In described device, described housing top establishes display module, and battery cabin cap, on and off switch and function button are fixed on the position that housing side is suitable for operating or watching;
In detector body, the electrical connection of the parts such as left control circuit board, right control circuit board, display module, on and off switch, function button, LD light source module, precise light electric diode, battery forms circuit control system, wherein right control circuit board realizes the major control function of system, comprise and the state of on and off switch, function button is detected, LD light source module, display module etc. are controlled; Left control circuit board mainly realize power supply and to precise light electric diode measurement data acquisition, the DC/DC chip of left control circuit board is connected with battery, signal amplification circuit is connected with precise light electric diode, and the amplification of precise light electric diode low current signal is converted into voltage signal; AD sampling A/D chip is connected with signal amplification circuit, and the analogue signal of amplifying circuit is converted to digital signal, and signal is sent to right control circuit board.
Adopt above design, the present invention achieves with relatively simple and reliable design and construction the function that near infrared light detects the cephalophyma wounded; Its main feature is:
1. integrated form fibre-optical probe, can realize following functions simultaneously:
● light source probe and the motion of detector probe standalone elastic, can adapt to head different curve shape;
● design can, to the structure of inner circuit realiration electromagnetic shielding, make detector avoid by external interference.
● be integrated with light source module, detector module and optical fiber/light source couples, optical fiber/detector optical filtering be coupled.
● achieve the little cost convenient changing of probe consumptive material.
2. devise the shade that can slide up and down
During the detection wounded, shade up, testing staff accurately can judge the contact situation of fibre-optical probe and wounded's scalp, after confirming that fibre-optical probe contacts with wounded's scalp, promote shade downwards again, shade and wounded's head Surface forming darkroom, block extraneous light to enter, prevent the extraneous light interferometry such as outdoor or indoor high light.
Accompanying drawing explanation
Figure 1A is that Near-infrared Brain hematoma detector of the present invention is formed and schematic appearance.
Figure 1B is shade motion schematic diagram in the direction of the arrow in Near-infrared Brain hematoma detector.
Fig. 1 C is shading cover structure composition schematic diagram
Fig. 2 A and Fig. 2 B is that the outside of detector body 1 forms schematic diagram.
Fig. 3 A and Fig. 3 B is the Inner Constitution schematic diagram of detector body 1.
Fig. 3 C is detector body 1 base and probe positions and connection layout.
Fig. 4 A is the structure chart of Elastic probe mechanism of the present invention.
Fig. 4 B is structural representation after spring probe mechanism removes radome and spring (further illustrating the schematic diagram of spring probe mechanism structure).
Fig. 4 C is spring probe mechanism kinematic schematic diagram.
Fig. 5 A is the schematic diagram of replaceable fibre-optical probe structure in the present invention.
Fig. 5 B is taper mount pad structural representation.
Fig. 5 C is that in the present invention, fibre-optical probe coordinates mounting structure figure with taper mount pad.
Fig. 5 D is fibre-optical probe structure chart in the present invention.
The photoelectric cell of Fig. 6 A display light source probe.
Fig. 6 B shows the photoelectric cell of detector probe.
Fig. 7 is the circuit controling drawing of Near-infrared Brain hematoma detector of the present invention.
Fig. 8 is Near-infrared Brain hematoma detector measurement procedure figure of the present invention.
Fig. 9 A is light source light power and the graph of a relation of time in usually detecting.
Fig. 9 B is light source light power and the graph of a relation of time during the present invention detects.
Figure 10 A is No. 1 wounded's brain CT photo (left temporal lobe intradural hematoma) that the present invention detects.
Figure 10 B is No. 8 wounded's brain CT photos (right parietal lobe hematoma) that the present invention detects.
Detailed description of the invention
The inspection of near-infrared hand-held cephalophyma hinder instrument be mainly used in institute before, war is on-the-spot etc. without using in CT situation, traumatic cerebral hematoma can be detected fast in early days, comprise in frontal lobe, temporal lobe, top and occipital lobe cranium brain position dura mater, Subdural space, arachnoidea and Cerebral cortex hematoma, the cephalophyma wounded are given treatment to timely.
Its know-why: the near infrared light of wavelength 600-900nm has good penetrance to skin, skull, based on intracranial hematoma and non-Hemorrhagic location to near-infrared absorption difference of coefficients (usually reaching more than 10 times), by comparing wounded's brain antimere to the absorption characteristic of near infrared light, judge intracranial hematoma risk.
ΔOD = log 10 ( I N I H )
Wherein, Δ OD is both sides optical density difference, I nfor normal side optical density, I hfor hematoma sidelight density.
The present invention utilizes the inspection of this principle design novel near-infrared hand-held cephalophyma to hinder instrument.The embodiment provided below in conjunction with accompanying drawing illustrates concrete formation of the present invention, operation principle and testing process.
Figure 1A and Figure 1B shows Near-infrared Brain hematoma detector pie graph of the present invention, it comprises detector body 1 and shade 2 (see Figure 1B) two parts, wherein, the ergonomic designs of detector body 1 outward appearance for ease of gripping, is provided with for the smaller one section of slide-and-guide post 14 (shown in composition graphs 2A) of the descending Outside Dimensions of shade 2 in its lower end, shade 2 by dark shading soft material as silica gel, rubber or other similar material molding, it is sleeved on outside detector body 1 lower slide lead 14, shade 2 inside upper part is provided with the sliding pair matched with slide-and-guide post 14 shape and size, as shown in Figure 1 C, such as, the slide unit 21 matched with slide-and-guide post 14 form factor is designed with inside shade 2, this slide unit 21 is by nylon or the little polymer material molding of other frictional resistance, smooth surface, in the groove that the soft cover body 22 that one end can embed shade 2 designs, the other end is fastened in slide-and-guide post 14 outer rim, contact with slide-and-guide post 14 when sliding and be easy to relative motion, make shade 2 can move a distance along the slide-and-guide post 14 of detector body 1, when shade 2 is moved down into base 15 (shown in Fig. 2 A) place of detector body 1, shown in Figure 1B, because the design of base 15 outer protrudes from slide-and-guide post 14, block shade 2 can not move down again, form certain displacement: when shade 2 moving to the top of distance (slightly larger than slide-and-guide post 14 Outside Dimensions, detector body 1 epimere size stops that shade 2 moves on continuing), make the probe 18 that can expose detector body 1 front end, 19 (shown in composition graphs 2A), the person of being convenient for measuring judges whether contact with the scalp of the wounded when measuring, when shade 2 be displaced downwardly to distance bottom time (base 15 outer design protrude from slide-and-guide post 14, block shade 2 can not move down again), the design of its displacement makes soft cover body 22 times edges of shade 2 exceed probe 18,19, so that while probe with head curved face contact, shade 2 and head form darkroom, local jointly, can stop that extraneous light enters probe, reduce extraneous light to the impact detected.
The outside that Fig. 2 A and Fig. 2 B shows detector body 1 is formed.It comprises one by macromolecular material (as ABS, PVC etc.) material injection forms, shape is convenient to the hollow housing 12 gripped, housing top fixes display module 11, battery cabin cap 13, the funtion parts such as on and off switch 16 and function button 17 are fixed on by buckle and screw thread the position that housing side is suitable for operation or viewing, the slide-and-guide post 14 that peripheral dimension is slightly less than housing 12 is extended in housing 12 bottom, housing 12 lowermost end is provided with base 15, base 15 outside dimensions is slightly larger than the peripheral dimension of slide-and-guide post 14, base 15 is equipped with the light source probe 18 and detector probe 19 that stretch out downwards.
Fig. 3 A and Fig. 3 B shows the Inner Constitution of detector body 1, comprise by grafting be threaded fastening with base 15 and the vertical control circuit board parallel with two pieces of base, i.e. left control circuit board 31 and right control circuit board 32, the side of left control circuit board 31 and right control circuit board 32 parallel edges is vertical establishes battery bin 33, wherein install 2AA battery, by battery cabin cap 13 fetching battery being located at outside correspondence position, battery the two poles of the earth are connected into circuit board, all Circuits System are all connected by the energising of standard connection-peg, by 2AA battery powered, (battery powered forms stable ± 12V by the power management chip on control circuit board, + 5V, + 3V powers to modules respectively).Light source probe 18 and detector probe 19 distributing installation are in the middle of left control circuit board 31 with right control circuit board 32 and be connected with base 15, composition graphs 3C, light source probe 18, detector probe 19 have threaded mounting hole, be fixedly connected with base 15 by screw is fixing, probe tip (see Fig. 3 C) is protuberate basic unit 15 downwards, and between light source probe 18 and detector probe 19 liang of tips, optimal distance is 3-5cm.During assembling, the epimere of left control circuit board 31, right control circuit board 32, battery bin 33 and light source probe 18 and detector probe 19 is all closed in the space that housing 12 and base 15 surround, battery, to be electrically connected between circuit board and probe, so to form detector body 1.
In the present invention, light source probe 18 becomes spring probe mechanism with detector probe 19 optimal design.
Fig. 4 A, 4B, 4C illustrate the formation of this spring probe mechanism for light source probe 18.Light source probe 18 includes radome 181, mount pad 182, spring 183 and conical seat 184 and fibre-optical probe 185, wherein, radome 181 is the cylindrical cavity (see Fig. 3 C and Fig. 4 A) of band side open surface, being made up of metal materials such as aluminum, copper, steel (can to inner circuit realiration electromagnetic shielding, detector is avoided by external interference), through hole is offered for drawing the electricity supply and control line of the photoelectric cell of installing in mount pad 182 in its upper end, lower end establishes the end of evagination in order to fix with base 15, and radome 181 bottom and base 15 relative position all have opening.The step-like hollow posts that mount pad 182 reduces for downward size, axially be sleeved on the interior also bottom of cavity of radome 181 through the opening of base 15, mount pad 182 designs step convex tendon, its maximum outside diameter is equal with radome 181 internal diameter, bottom minimum outer diameter is equal with the opening of base 15, two place's matching design are that mount pad 182 provides motion guide, and mount pad 182 like this can be fixedly mounted on base 15.Mount pad 182 has the elongated hole 1821 that two longitudinal directions have certain length relatively in upper end, its step convex tendon top is provided with step, sheathed spring 183 on step, the bottom of spring 183 props up mount pad 182 and designs step convex tendon, and its drift higher than elongated hole 1821 bottom.The relevant position of radome 181 also has screw 188, first below elongated hole 1821 height spring 183 being compressed to mount pad 182 during installation, use length can penetrate two elongated holes 1821 and the screw 186 stretching into wherein 2-4mm screws in mount pad 182 upper end elongated hole 1821 from radome 181 screw 188, bottom due to spring 183 props up mount pad 182 and designs step convex tendon, upper end screw 186 pressuring spring 183 makes spring 183 have certain pre-elasticity, a distance is had to become " displacement d " (Fig. 4 C) between the top of mount pad 182 top and radome 181, mount pad 182 can be realized and flexibly move up and down certain distance.In addition, the screw 186 using length can stretch into the 2-4mm of two elongated holes 1821 can prevent the rotary motion of mount pad 182 and radome 181 simultaneously, this rotary motion may cause the damage of mount pad 182 inner lead (see Fig. 6 A, to be equiped with LD light source module 186 and collimating lens 188 from top to bottom inside the mount pad for light source device probe 18; Precise light electric diode 191 and optical filter 192 is equipped with from top to bottom, see Fig. 6 B) in the mount pad of detector probe 19.
Equally, detector probe 19 possesses independently elastic movement ability up and down by same mode.
Continue shown in composition graphs 5A, Fig. 5 B, Fig. 5 C and Fig. 5 D, show the present invention's replaceable fibre-optical probe structure: conical seat 184 is arranged in the bottom of mount pad 182 by mode that is bonding or that be threaded, Fig. 5 B shows conical seat 184 inside and is longitudinally provided with through hole, as the fibre-optical probe installing hole 1845 of fibre-optical probe 185, installation direction is from bottom to top (Fig. 5 C shows installation process).Conical seat 184 has two horizontal elongated holes in cylinder partial bottom, the endoporus of elongated hole is the centre bore 1841 of inside convergent, from the inside to the outside steel ball 1843, spring 1844 and jackscrew 1,842 three parts are installed respectively in hole, minimum-value aperture design due to centre bore 1841 is less than the diameter of steel ball 1843, give prominence to by the elasticity in centre bore 1841 of steel ball 1843 after jackscrew 1842 pretension, fibre-optical probe 185 to intert in fibre-optical probe installing hole 1845.The present invention achieves the replacing of fibre-optical probe consumptive material by changing fibre-optical probe structure.When fibre-optical probe 185 inserts, the groove of its upper design can with can coordinate with the steel ball 1843 outstanding to elasticity in installing hole 1845 in the centre bore 1841 of conical seat 184, fibre-optical probe 185 position is made to be fixed in conical seat 184, can not drop out, it is convenient to change, and can complete light conduction function simultaneously.When detection complete wounded after, can conveniently with hands exert a force downwards drawn optical fiber probe 185, the fibre-optical probe 185 more renewed.
Continue shown in composition graphs 5D, fibre-optical probe 185 is made up of three parts, and fibre-optical probe seat 1851 or one-shot forming bonding with optical fiber protective tube 1852 and optical fiber 1853, can entirety change as consumptive material; Optical fiber protective tube 1852 is made for metal or other material, effectively can protect optical fiber 1853, and prevents light from directly propagating between two probes, causes measuring unsuccessfully; Optical fiber 1853 and human body contact portion's (lowermost end) are designed to hemisphere face to reduce and discomfort during head part's contact skin.Fibre-optical probe 185 constructional simplicity of this design can be reliable, and manufacturing cost and technology difficulty are very low, ensure that it becomes droppable low value consumptive material.
The light source probe 18 that the present invention relates to, detector probe 19 all can adopt fibre-optical probe 185 identical as shown in Figure 5 D, and such light source probe 18 and detector probe 19 can facilitate the replacing fibre-optical probe 185 without distinguishing.
In the present invention, Fig. 6 A shows the optical element of light source probe 18.The light source module 186 of installing in mount pad 182 is LD light source module (inside comprises LD laser instrument, module mount pad and control circuit), LD light source module can screw in mount pad 182 (see Fig. 5 A and Fig. 5 B) by screw thread, collimating lens 188 also screws in mount pad 182 by screw thread from below, and the distance of itself and light source module 186 lower end is 1-4mm.The near infrared light of the 808nm that LD light source module 186 sends, by being coupled to fibre-optical probe 185 upper surface after collimating lens 188, being derived (as Fig. 6 A direction of arrow) by the optical fiber 1853 in fibre-optical probe, is realized the function of light source optical path.
Fig. 6 B shows the optical element of detector probe 19.In mount pad 182, precise light electric diode 191 (carrying elementary operational amplification circuit) is arranged at top, installs optical filter 192 immediately below it, and the upper end of fibre-optical probe 185 and optical filter 192 are close to the coupling efficiency installed to ensure light.The light (as Fig. 6 B direction of arrow) that scattering returns from cerebral tissue is imported by the optical fiber 1853 in fibre-optical probe 185, by optical filter 192 filter out wherein most non-808nm infrared light to reduce the interference of extraneous light, be coupled in precise light electric diode 191, realize the function detecting light path.By circuit control system (explained later), the optical signal that precise light electric diode 191 gathers is converted to the signal of telecommunication and from the through hole of radome 181 upper end, leads to display module 11 by lead-in wire.
Circuit control system of the present invention is shown in Fig. 7, comprise the parts such as left control circuit board 31, right control circuit board 32, display module 11, on and off switch 16, function button 17, LD light source module 186, precise light electric diode 191, battery, as shown in Figure 7, in figure, the direction of arrow is that data or signal flow to each parts annexation.Right control circuit board 32 realizes the major control function of system, comprises and detecting the state of on and off switch 16, function button 17, control LD light source module 186, display module 11 etc.; Left control circuit board 31 mainly realizes power supply and to precise light electric diode 191 measurement data acquisition.
Wherein: left control circuit board 31 is formed primarily of known DC/DC chip, signal amplification circuit, AD sampling A/D chip.DC/DC chip is connected with battery, and by stable 3.3V, the 5V of 2-3V voltage transitions needed for the Circuits System, ± 12V voltage of 2 joints No. 5 aneroid battery, to system power supply, all Circuits System elements are all by standard connection-peg energising connection.Signal amplification circuit is connected with precise light electric diode 191, mainly realizes the amplification of precise light electric diode 191 low current signal, is converted into voltage signal; AD sampling A/D chip is connected with signal amplification circuit, and the analogue signal of amplifying circuit is converted to digital signal, and signal is sent to right control circuit board 32.
Here, signal amplification circuit will comprise more than two-stage usually.Under a kind of implementation, design two-stage amplifying circuit, the low current signal of precise light electric diode 191 is transformed to mV magnitude voltage signals by elementary amplifying circuit, and this signal amplifies by second level amplifying circuit more further.Because the measuring-signal of precise light electric diode 191 affects by skull thickness, hair density degree etc., make measuring-signal individual variation huge, for meeting kinetic measurement requirement, design second level amplifying circuit can realize the dynamic conditioning (concrete method of adjustment hereafter describes in detail) of gain amplifier.Under another kind of implementation, can also design third level amplifying circuit, object is the filtering that can realize signal on this grade of amplifying circuit.Elementary amplifying circuit is generally selected specially for the amplifying circuit chip of photodiode signal process, and as OPA128 etc., second, third grade of amplifying circuit can select general amplifier to realize.
AD sampling A/D chip is chosen and should be noted sample frequency (being usually not less than 1MHz), and certainty of measurement is minimum is 10, and a kind of implementation can choose AD7960.
Right control circuit board 32 is formed primarily of Single Chip Microcomputer (SCM) system, a kind of implementation can adopt 51 series monolithics, as C8051F330, its rich interface, UART serial ports is had conveniently to be connected with display module 11, have SPI serial ports to facilitate to be connected with the AD sampling A/D chip of left control circuit board 31, digital I/O mouth is connected with on and off switch 16, function button 17 and LD light source module 186 respectively, can realize the detection of on and off switch and function button and the control of LD light source module.
Be mounted with in single-chip microcomputer: 1) known photo densitometry algorithm, this algorithm is sensitivity according to photodiode 191, the digital-to-analogue corresponding relation of circuit amplification, AD sampling determines the luminous power that measures, then gets denary logarithm to this luminous power and obtains optical density;
2) the test point sequential programme preset, this order is preset as left frontal lobe LF/ right frontal lobe RF, the left temporal lobe of LT/right temporal lobe RT, left parietal lobe LP/ right parietal lobe RP, the order of left occipital lobe LO/ right occipital lobe RO, the order pressing the corresponding measurement point of number of times of function button 17 realizes the optical density under point-to-point measurement each position;
3) switching programme of LD light source module 186, LD light source module is modulated to the pulse that width is 10ms, and the pulse spacing is about 167ms, then in the process of sampling, open light source, light source is in closed condition At All Other Times.
4) output of LD light source and the amplification adjustment programme of circuit: light source power can be set to 2 power shelves, corresponding different luminous powers, such as, can arrange the light source peak power output of power shelves 1,2 difference corresponding 100%, 20%.The amplification of measuring circuit realizes by adopting the amplifier amplifier of adjustable amplification, usually the adjustment of amplification is arranged on the afterbody amplifier of amplifying circuit, adopt 3 gears, the amplification of afterbody can be set to 1,10,100.Luminous power and amplification have 9 to combine, and programme-control these 9 combination detects measurement point one by one according to fixing order, obtains data.The data finally chosen are the data of the 10%-70% in testing circuit measuring range.
Precise light electric diode 191: dark current little (being less than 30pA under normal circumstances) should be chosen and the chip of measurement frequency band wider (band is wider than 1KHz), chip is at the near infrared region measurement sensistivity of about 800nm at 0.5A/W, and a kind of implementation can select the S2386 of the river in Jiangsu Province which flows into the Huangpu River of Shanghai, shore optics.
LD light source module 186: the LD module of strobe pulse modulation, the modulating frequency of LD light source should be greater than 10KHz and (be different from existing continuous light cephalophyma checkout equipment, existing equipment frequency is close to 100Hz), the present invention adopts pulse modulated LD as light source, coordinate the LD light source control mode (by Single-chip Controlling pulse type switch) and precise light electric diode data sampling optimized, the measurement under low light source mean power can be realized, its advantage is ensureing to make the luminous power needed for measurement minimum under same measurement sensistivity, thus greatly reduce the risk of measurement.LD light source module 186 contains the constant-current source circuit driving LD, and can realize controlling Output optical power by adjusting resistance or voltage.Under a kind of implementation, LD constant-current source circuit can take chip TCA62723 to realize.
Display module 11: mainly realize the function such as the prompting of measuring position, the display of measurement result in measuring process.Under a kind of implementation, display module can take LED screen, is characterized in low in energy consumption; Under another kind of implementation, display module can take charactron, is characterized in intuitive display, realizes simply; Under another kind of implementation, display module can take dot matrix LCD screen, is characterized in that displaying contents enriches.
The each parts assembling designed above is obtained Near-infrared Brain hematoma detector of the present invention.
Use this Near-infrared Brain hematoma detector to detect, idiographic flow is see Fig. 8.Process comprises:
(1) tested personnel are checked with sitting posture or prone position, should clear up head dirt before detection;
(2) detector is opened by and off switch 16;
(3) fibre-optical probe 185 of light source probe 18 and detector probe 19 is assembled;
(4) push detection position hair aside with hands, expose scalp, fibre-optical probe 185 is touched scalp (light source probe 18 and detector probe 19 are positioned at and detect in the middle of position), probe orientation is tested skull face normal direction;
(5) downward pressing detection instrument housing, with regard to compressible elastomeric probe, is pressed into total travel (to spring-compressed state) by having springing stroke (in relaxing of spring state); Total travel refers to spring-compressed distance, is the displacement of Fig. 4.
(6) push shade 2 probe is covered completely, stop that extraneous light is to the interference of measuring;
(7) press function button 17 to measure, demonstrate this measuring position optical density value OD (usual Measuring Time is 10s) to display module 11, this detection position measures complete;
(8) upwards push away shade 2, the step repeating (4)-(7) detects next measuring position;
(9) after 8 measurement points have all been measured, Automatic Program start-up simulation, has tested rear display measurement result.
Here: in step (7), for each measurement point, instrument will obtain the optical density value OD of this measurement point by LD light source irradiation gained, if the sensitivity of photoelectric diode is S (unit is A/W), if the gain of elementary amplifying circuit is O 1(unit is V/A), the 2nd, 3rd level overall gain is O 2, amplifying circuit output signal voltage V 0, then
V 0=OD·S·O 1·O 2
Optimize one: for improving measurement data anti-interference, repeated measure will be carried out repeatedly to eliminate the error of single measurement to each measurement point; Simultaneously for eliminate bias light on measure impact, to light source do not open with open after signal measure respectively.If repeated measure number of times is n, light source does not open lower optical density value average out to OD c, the OD average that light source is measured after opening is OD o, then have:
OD c = 1 n Σ i = 1 n OD ci
OD o = 1 n Σ i = 1 n OD oi
The optical density value OD of final current measurement point is the poor OD of the front OD average with unlatching after light source is opened o-OD c, thus effectively eliminate the interference of bias light.
Optimize two: for realizing significantly reducing the target of light source power under the prerequisite not affecting measurement sensistivity, need to be optimized LD light source control mode.Its major measure be only allow sampling process in open light source, light source is in closed condition and (passes through programme-control At All Other Times, select pulse modulated light source, the switch of the type light source is controlled by the level of single-chip microcomputer numeral output pin, thus conveniently can control light source open and close).For the Measuring Time of each measurement point 10s (this is the common Measuring Time of each measurement point of this quasi-instrument), the advantage optimizing LD light source control mode is described.Common way (is pressed to this point from function button and measures end, 10s) in the process of current measurement point measurement, and LD light source is in opening all the time, then the relation of luminous power and time is shown in Fig. 9 A.The present invention sets the AD sampling time as 10ms, each measurement point often plants luminous power and amplification combines repeated measure number of times to be 10, then after optimizing, luminous power and the relation of time are shown in Fig. 9 B, visible, the pulse of LD modulation of source of the present invention to be width be 10ms, the pulse spacing is about 167ms.The relatively radiated light energy (calculated by area under curve in figure and obtain) of LD light source, under measuring method before optimization, the radiated light energy of single measurement point is 0.175J (Fig. 9 A), and after optimizing, the radiated light energy of single measurement point is 0.0105J (Fig. 9 B).After optimizing, radiated light energy greatly declines (for 6% before optimization), effectively reduces the power consumption of instrument, improves the safety of Laser Measurement simultaneously.
Optimize three: for making gauge adapt to huge individual variation, in measurement, answer the output of dynamic conditioning LD light source and the amplification of circuit.Under a kind of implementation, light source power can be set to 2 grades (Output optical power is respectively 30mW and 5mW), the overall gain of amplifying circuit is set to 3 grades and (is respectively ) (adjustment of light source power is by adjustment light source power supply electric current, light source is powered by constant-current source, the supply current adjustment light source output power of adjustable constant-current source), then all can measure according to the combination of different luminous powers and gain amplifier at each measurement point, final optical power value chooses signal amplitude (initial data of optical density computing) numerical value placed in the middle, thus can effectively avoid signal gets too small or exceed the situation of measuring range.Such as circuit measuring scope is 0-5V, then measurement data chooses the data of 0.1V-4.5V usually.
Here, detection ordering in step (8): a kind of order is that testing staff is according to left frontal lobe LF/ right frontal lobe RF, the left temporal lobe of LT/right temporal lobe RT, left parietal lobe LP/ right parietal lobe RP, the order of left occipital lobe LO/ right occipital lobe RO is carried out detecting and (in detector single-chip microcomputer, has been preset measuring sequence, every bit presses a function button 17), when noting detecting, the difference of symmetrical position must not be greater than 3cm.After these 8 measurement points have all been measured, display measurement result on display module.
Another kind of order is, function button 17 is coordinated to realize the selection of measuring position sequencing: the long order that can change current measurement position by function button 17, if think first to measure right temporal lobe, then 3 vice-minister can press function button, first skip the measurement of left frontal lobe, right frontal lobe, left temporal lobe.After required measurement point has all been measured according to the selecting sequence of user, detector display measurement result.Such implementation advantage is to provide convenient (such as determine that position is checked to certain, then detect one by one without the need to carrying out 8 measurement points) to user, makes measuring sequence not be only according to the carrying out of setting in advance.
Here, in step (9), after 8 measurement points have all been measured, single-chip microcomputer has started computation and measurement result.If the optical density of left side volume, temporo, top, pillow is designated as OD respectively lF, OD lT, OD lP, OD lO, the optical density of right side volume, temporo, top, pillow is designated as OD respectively rF, OD rT, OD rP, OD rO, then the optical density difference of volume, temporo, top, pillow 4 groups of antimeres is respectively:
ΔOD F=OD LF-OD RF
ΔOD T=OD LT-OD RT
ΔOD P=OD LP-OD RP
ΔOD O=OD LO-OD RO
As long as the optical density difference of volume, temporo, top, pillow has absolute value to be greater than 0.3, then it is determined that the presence of cephalophyma, optical density difference be canonical on right side, for negative then in left side.If the absolute value of the optical density difference of volume, temporo, top, pillow is greater than 0.2 and be less than or equal to 0.3, then suspect the excessive risk that there is cephalophyma, optical density difference is that canonical is suspected on right side, then suspects in left side for negative.If the absolute value of the optical density difference of volume, temporo, top, pillow is all less than or equal to 0.2, then judge without cephalophyma.For example, if optical density difference data are (frontal lobe F)-0.12, (temporal lobe T) is 0.37, (top P) is-0.25, (occipital lobe O) is 0.06, then be judged to be that right side temporal lobe exists hematoma, left side top suspects the risk having hematoma, and frontal lobe and occipital lobe are without hematoma.
Detection example (clinical trial):
Instrument model machine of the present invention is used to carry out Clinical Laboratory (cooperating with Nao Ke hospital of Affiliated Hospital of People's Armed Police's logistics institute, Tiantan Hospital), interim result shows, detection specificity and the sensitivity of model machine all meet designing requirement, all 9 routine wounded's test results are consistent with CT scan result, the left figure of Figure 10 A is the CT figure of No. 1 wounded's head, right figure is apparatus of the present invention detection figure, equally, the left figure of Figure 10 B is the CT picture of No. 8 wounded's heads, right figure is apparatus of the present invention detection figure, and 9 wounded's testing results of all detections are in table 1.Confirm the effectiveness that near-infrared hand-held cephalophyma detector is applied.
Table 1 clinical test results (age 19-85 year man 6 female 39 wounded)
Sequence number CT testing result This device testing result
1 Left temporo intradural hematoma, about 30ml Left temporal lobe hematoma, frontal lobe is normal
2 Right parietal lobe intradural hematoma, 5ml Right parietal lobe hematoma, temporal lobe is normal
3 Contre coup injury, left top, temporal lobe hematoma 50ml Left top, temporal lobe hematoma, frontal lobe is normal
4 Contre coup injury, left temporal lobe hematoma 10ml Left temporal lobe hematoma, frontal lobe, top are normal
5 Right frontal lobe subdural hematoma is about 40ml Right frontal lobe hematoma, top, temporal lobe are normal
6 Left temporal lobe subdural hematoma 30ml Left temporal lobe hematoma, frontal lobe, top are normal
7 Left pillow, top intradural hematoma 10ml Left occipital lobe, left parietal lobe hematoma volume, temporal lobe are normal
8 Right parietal lobe subdural hematoma 20ml Right parietal lobe hematoma frontal lobe is normal
9 Left frontal lobe contre coup injury hematoma 5ml Left frontal lobe hematoma, top, temporal lobe are normal
For No. 1 wounded, its each location detection data are as table 2:
The detection data of table 2 No. 1 wounded
Frontal lobe F Temporal lobe T Top P Occipital lobe O
Left side measured value OD L 4.11 3.25 3.12 3.65
Right side measured value OD R 3.99 3.67 3.25 3.76
Optical density difference Δ OD 0.12 0.42 0.13 0.11
From table 2 measurement data, have detected the frontal lobe of No. 1 wounded, temporal lobe, top and the symmetrical part of occipital lobe totally 8 data respectively with this detector, wherein, the optical density difference of frontal lobe, top and occipital lobe is all less than 0.3, can judge that No. 1 wounded's frontal lobe, top and occipital lobe are without hematoma.The measurement result of its temporal lobe shows, it is 0.42 that left and right optical density difference is greater than, and is greater than decision content 0.3, therefore, can think that No. 1 wounded's temporal lobe part exists cephalophyma, and due to left side measured value less, therefore, instrument judges that the left temporal lobe of No. 1 wounded exists cephalophyma.The Cranial Computed Tomography scanning result of No. 1 wounded shown in composition graphs 10A, CT scan result also judges that the left temporal lobe of No. 1 wounded exists cephalophyma, and both testing results are consistent.The Cranial Computed Tomography scanning result of No. 8 wounded that Figure 10 B shows also coincide with this detector testing result.
Feature of the present invention:
1. integrated form fibre-optical probe, can realize following functions simultaneously:
● the standalone elastic motion separately of light source probe 18 and detector probe 19, can adapt to head different curve shape.
US Patent No. 8060189 Figure 15 B shows it and realizes the elastic mode of fibre-optical probe, light source probe and detector probe (label 1428) respectively on connect spring (bias elements1560), be arranged on hard planar delta parts (platform 1510), but, this implementation also exists problem, two probe is arranged on hard planar delta parts, and these rigid planar parts (label 1510) are by the restriction of three guide pillars (label 1505), its planar delta parts 1510 and probe 1428 can only move up and down simultaneously, although elasticity that this method for designing has made probe possess, but there is the following shortcoming that cannot overcome:
(1) cannot self-movement between light source probe and detector probe, the motion of two probes is identical, namely the athletic meeting of a probe affects the motion of another probe, cause itself and human body head complex-curved incompatible like this, cause probe well cannot attach with the curved surface of human body head, have impact on the accuracy of measurement.
(2) this design probe and light source or detector direct-coupling, cause the non-exchange of consumptive material of popping one's head in.
(3) complex structure, volume is large, have compressed the layout of other necessary parts.
Therefore, although US Patent No. 8060189 refer to elastic problem in the claims, and the mode claiming to scheme A solves probe elastic problem, due to above three apparent problems, in practice and unrealized.Actually in type cephalophyma scanning ceremony in product 1000 type/2000 disclosed in it have employed in patent the scheme scheming B, that is, do not adopt spring probe to design, achieve the replaceability of probe (Figure 16 E) as consumptive material.
But, but the design of Figure 16 E brings problem: US Patent No. 8060189 also shows that probe has elastic importance, one is well can fit with head curved surface, affect accuracy of measurement, two is that the dynamics that probe contacts with scalp also affects accuracy of measurement, but its uncontrollable contact force can bring discomfort to measured.In Figure 16 E, removable probe cover volume is large, limited as probe consumptive material carrying amount, and waste resource, does not meet the requirement of environmental protection.
● light source probe and detector probe are all designed with electro-magnetic shielding cover, can, to inner circuit realiration electromagnetic shielding, detector be avoided by external interference.
● be integrated with light source module, detector module and optical fiber/light source couples, optical fiber/detector optical filtering be coupled.The present invention is by adopting the probe 18 of integrated morphology, and 19 achieve coupling.
● and two sonde configurations are simple, volume mass is small, conveniently carries in a large number as low price consumptive material; Achieve probe consumptive material convenient changing.
The present invention achieves the replacing of fibre-optical probe consumptive material by the replacing fibre-optical probe structural design that conical seat and fibre-optical probe form, and light source probe is identical with the fibre-optical probe in detector probe, without the need to distinguishing during replacing, can exchange.And the probe cover that US Patent No. 8060189 need be changed at every turn (1600 of Figure 16 D and 16E), this probe cover will complete the functions such as shading, optical fiber mount pad, sealing simultaneously, complex structure, volume are large, as consumptive material, not only carrying amount is limited, and waste resource, do not meet the requirement of environmental protection.
2. devise the shade that can slide up and down
When the present invention detects the wounded, shade up, and testing staff accurately can judge the contact situation of fibre-optical probe and wounded's scalp, after confirming that fibre-optical probe contacts with wounded's scalp, promote shade downwards again, shade and wounded's head form darkroom, block extraneous light and enter, interferometry.
Though US Patent No. 8060189 is also provided with an opaque shade, diaphragm system expressed on its Fig. 4 A is similar to the application, but existing problems: its shade is fixing on base, and in order to prevent extraneous light from entering measuring system, the length of shade is greater than the length of fibre-optical probe, like this when detecting the wounded, due to the stop of shade, cause medical worker cannot judge to pop one's head in whether push down the hair of the wounded, make measurement become unreliable.In order to address this problem, this patent shows to realize shading in the mode under its Fig. 4 B, the i.e. light screening material of direct metal or other material on outer fiber cover, although avoid the upper figure Problems existing of its figure C like this, when ambient light is stronger, due to the near infrared light of environment fibre-optical also containing 808nm, directly or indirectly (from tissue scatter) detector probe may be entered, form interfering signal, affect measurement result, measurement can be made equally to become unreliable.Therefore, in actual use, the product formed with United States Patent (USP) does not adopt the mode of its Fig. 4 A, and requires when measuring to avoid strong ambient light as far as possible, and requires to live measuring point when measurement with stick shift, prevents ambient light from entering measuring system.
Adopt the structure of slidingtype shade and the nested metal tube of outer fiber in the present invention in design, avoid this problem, improve the accuracy of measurement, and be structurally easy to realize.
3.LD light source pulse formula switch designs, (have detector, comprise US Patent No. 8060189) before light source self radiated light energy greatly drops to optimization 6%, effectively reduce the power consumption of instrument, improve the safety of Laser Measurement simultaneously.
4. complete machine height is integrated, global design compact conformation, light and handy, and weight is containing two joint AA battery only 500g, and overall dimensions only has 135 × 65 × 80mm, and consumptive material (fibre-optical probe) is little, can facilitate and carry in a large number.
5. testing process fathoms as 3mm, noinvasive, fast, accurately, and without any need for reagent.Can say that this equipment realizes with simple and reliable structure and reaches state's former advanced level of similar equipment, certain this index is better than same kind of products at abroad.The major parameter of several known detector compares in table 3.
Table 3 equipment technology performance comparison
Crainscan Inftrascanner1000 The present invention equips
The place of production The U.S. The U.S. Domestic development
Design form Hand-held Hand-held Hand-held
Detect position Volume, temporo, occipital lobe Volume, temporo, top, occipital lobe Volume, temporo, top, occipital lobe
Detection sensitivity 88.5% 88% Be greater than 90%
Detection specificity 83.3% 90.7% Be greater than 90%
Blood volume can be detected -- Be not more than 3.5ml Be not more than 3.5ml
Detect the degree of depth Subcutaneous 3cm Subcutaneous 3.5cm Subcutaneous 3.5cm
Detection time 2min 3min 2min

Claims (10)

1. device is hindered in a hand-held Near-infrared Brain hematoma inspection, comprise the detector body containing light source probe and detector probe, also comprise a shade, it is characterized in that, described detector body lower part establishes slide-and-guide post, shade is by the molding of dark shading soft material, for the cover body to lower open mouth, this is external to be sleeved on detector, and shade inside upper part is provided with the sliding surface matched with slide-and-guide post shapes and size makes shade and detector body realize relative motion to be socketed slide-and-guide post.
2. device according to claim 1, is characterized in that, the hollow housing of detector body exterior for ease of gripping, and the slide-and-guide post outside dimensions of lower housing section certain length is slightly less than housing epimere peripheral dimension, moves distance to limit on shade; Housing lowermost end is provided with base, and base dimensions moves down size slightly larger than the peripheral dimension of slide-and-guide post with what limit shade; Base is equipped with the light source probe and detector probe that stretch out downwards.
3. device according to claim 2, it is characterized in that, shade is along when moving up and down in lead movable distance, the Design of length of shade is: make not block light source probe and detector probe during its top at slide-and-guide post, move it simultaneously to slide-and-guide post bottom time well beyond two probes, and darkroom can be formed with head curved face contact.
4. device according to Claims 2 or 3, it is characterized in that, detector body interior is equipped with perpendicular to two pieces of base parallel control circuit boards and left control circuit board and right control circuit board, and the battery bin of battery is housed, and battery the two poles of the earth are connected into control circuit board; Light source probe is connected and the downward protuberate basic unit of probe tip with base with detector probe distribution.
5. device according to claim 4, it is characterized in that, the epimere of left control circuit board, right control circuit board, battery bin and light source probe and detector probe is all closed in the space that housing and base surround, between light source probe and detector probe two tip, optimal distance is 3-5cm, and battery, circuit board and probe epimere are electrically connected.
6. device according to any one of claim 1 to 5, is characterized in that, described light source probe and detector probe are spring probe mechanism; This spring probe mechanism includes radome, mount pad, spring and conical seat and fibre-optical probe, wherein:
Radome is the cylindrical cavity of band side open surface, and through hole is offered for drawing the electricity supply and control line of the photoelectric cell installed in mount pad in its upper end, and lower end establishes the end of evagination in order to fix with base, and radome bottom and base relative position are equipped with opening;
Mount pad is step-like hollow posts, axially be sleeved on the interior also bottom of cavity of radome through base, mount pad is provided with step convex tendon, and its maximum outside diameter is equal with radome internal diameter, and bottom minimum outer diameter is equal to the opening of base to enable mount pad be fixedly mounted on base;
Mount pad upper end has two certain length elongated holes relatively, and its step convex tendon top is provided with step, sheathed spring on step, and the bottom of spring props up mount pad design step convex tendon, and its drift is greater than elongated hole length;
Conical seat is fixedly mounted on the bottom of mount pad, and it has longitudinal installing hole;
Fibre-optical probe interts in fibre-optical probe installing hole, is arranged on the bottom at mount pad.
7. device according to claim 6, it is characterized in that, mount pad is the step-like hollow posts that downward size reduces, axially be sleeved on the interior also bottom of cavity of radome through the opening of base, mount pad design step convex tendon, its maximum outside diameter is equal with radome internal diameter, and bottom minimum outer diameter is equal with the opening of base, to be fixedly mounted on base by mount pad;
Mount pad has the elongated hole that two longitudinal directions have certain length relatively in upper end, its step convex tendon top is provided with step, sheathed spring on step, and the bottom of spring props up mount pad design step convex tendon, and its drift higher than elongated hole bottom, the relevant position of radome also has screw, spring bottom props up the step convex tendon of mount pad, during installation with instrument or hands temporarily by spring top compression to mount pad elongated hole topmost below, and the space of screw screw-in can be reserved, the screw that can stretch into elongated hole 2-4mm by length screws in mount pad elongated hole from radome screw, the height of radome screw is original design just in time make screw screw in after be positioned at the elongated hole of mount pad topmost, pressuring spring makes spring have certain pre-elasticity by screw, there is a displacement to realize mount pad between mount pad top and the top of radome and flexibly move up and down certain distance.
8. device according to claim 7, is characterized in that, for light source probe is installed mount pad in be equiped with LD light source module and collimating lens from top to bottom, the distance of collimating lens and LD light source module lower end is 1-4mm; Or, for detector probe is installed mount pad in be equipped with precise light electric diode and optical filter from top to bottom, upper end and the optical filter of fibre-optical probe are close to installation.
9. device according to claim 6 or 7 or 8, it is characterized in that, the inner longitudinal hole of described conical seat is fibre-optical probe installing hole, establishes the centre bore of two laterally inwardly convergents, install steel ball, spring and jackscrew from the inside to the outside respectively in centre bore in its cylinder partial bottom;
Described fibre-optical probe consists of an entirety by fibre-optical probe seat, optical fiber protective tube and optical fiber, and optical fiber is arranged in optical fiber protective tube, and optical fiber front end is hemisphere face and stretches out optical fiber protective tube slightly forward, and fiber termination box optical fiber protective tube is fixed in fiber bench.
10. device according to any one of claim 1-9, is characterized in that, described housing top establishes display module, and battery cabin cap, on and off switch and function button are fixed on the position that housing side is suitable for operating or watching;
In detector body, the electrical connection of the parts such as left control circuit board, right control circuit board, display module, on and off switch, function button, LD light source module, precise light electric diode, battery forms circuit control system, wherein right control circuit board realizes the major control function of system, comprise and the state of on and off switch, function button is detected, LD light source module, display module etc. are controlled; Left control circuit board mainly realize power supply and to precise light electric diode measurement data acquisition, the DC/DC chip of left control circuit board is connected with battery, signal amplification circuit is connected with precise light electric diode, and the amplification of precise light electric diode low current signal is converted into voltage signal; AD sampling A/D chip is connected with signal amplification circuit, and the analogue signal of amplifying circuit is converted to digital signal, and signal is sent to right control circuit board.
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105011907A (en) * 2015-06-23 2015-11-04 南京航空航天大学 Detection equipment for abdominal bleeding
CN106618493A (en) * 2016-11-28 2017-05-10 武汉资联虹康科技股份有限公司 Probe fixing structure of near-infrared-spectrum brain function imaging device
CN108135474A (en) * 2015-06-24 2018-06-08 加利福尼亚大学董事会 Utilize flexible, the noninvasive real-time hemotoncus monitoring system of near infrared spectroscopy
CN109414193A (en) * 2016-05-17 2019-03-01 回弹治疗公司 Method and apparatus for positioning the color detection of the clot of intracerebral hematoma
CN110022757A (en) * 2016-09-28 2019-07-16 阿齐奥普迪克斯生物医药股份有限公司 Optical imaging apparatus and optical imaging apparatus lid
CN111065331A (en) * 2017-08-25 2020-04-24 红外线工程测试有限公司 Optical probe for blood oxygen measurement
CN118266877A (en) * 2024-05-31 2024-07-02 合肥科光量子科技有限公司 Multi-wavelength quantum detection device and method for detecting intracranial hemorrhage
CN118266876A (en) * 2024-05-31 2024-07-02 合肥科光量子科技有限公司 Preliminary screening tool for craniocerebral trauma

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2607951Y (en) * 2003-04-22 2004-03-31 厦门天众达科技股份有限公司 Painless blood sampler
WO2007038305A2 (en) * 2005-09-23 2007-04-05 Brain Scope Company, Inc. Electrode array
CN101347657A (en) * 2007-07-17 2009-01-21 深圳市蓝韵实业有限公司 Ultrasonic probe fixture mechanism applied to ultrasonic tumor treatment system
US8060189B2 (en) * 2005-05-06 2011-11-15 Infrascan, Inc. System and method for detection of hematoma
CN202078296U (en) * 2010-12-25 2011-12-21 刘军波 Vein observing instrument
CN202437095U (en) * 2012-01-09 2012-09-19 东莞市兴洲电子科技有限公司 Probe for infrared thermometer
CN102755158A (en) * 2011-04-25 2012-10-31 有医科技股份有限公司 Comb electrode
CN203290909U (en) * 2013-06-19 2013-11-20 张英泽 Laser ruler for surgery
CN204379247U (en) * 2014-12-01 2015-06-10 中国人民解放军军事医学科学院卫生装备研究所 Device is hindered in the inspection of a kind of hand-held Near-infrared Brain hematoma

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2607951Y (en) * 2003-04-22 2004-03-31 厦门天众达科技股份有限公司 Painless blood sampler
US8060189B2 (en) * 2005-05-06 2011-11-15 Infrascan, Inc. System and method for detection of hematoma
WO2007038305A2 (en) * 2005-09-23 2007-04-05 Brain Scope Company, Inc. Electrode array
WO2007038305A3 (en) * 2005-09-23 2007-08-09 Brain Scope Company Inc Electrode array
CN101347657A (en) * 2007-07-17 2009-01-21 深圳市蓝韵实业有限公司 Ultrasonic probe fixture mechanism applied to ultrasonic tumor treatment system
CN202078296U (en) * 2010-12-25 2011-12-21 刘军波 Vein observing instrument
CN102755158A (en) * 2011-04-25 2012-10-31 有医科技股份有限公司 Comb electrode
CN202437095U (en) * 2012-01-09 2012-09-19 东莞市兴洲电子科技有限公司 Probe for infrared thermometer
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US11622691B2 (en) 2017-08-25 2023-04-11 Infrascan Inc. Optical probe for oximetry measurements
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