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CN104430355A - Pesticide composition containing spinosad and application of the composition - Google Patents

Pesticide composition containing spinosad and application of the composition Download PDF

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Publication number
CN104430355A
CN104430355A CN201410687003.7A CN201410687003A CN104430355A CN 104430355 A CN104430355 A CN 104430355A CN 201410687003 A CN201410687003 A CN 201410687003A CN 104430355 A CN104430355 A CN 104430355A
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CN
China
Prior art keywords
agent
composition
pleocidin
suspending agent
composition according
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Pending
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CN201410687003.7A
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Chinese (zh)
Inventor
孙素一
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Individual
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Individual
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Priority to CN201410687003.7A priority Critical patent/CN104430355A/en
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Abstract

The invention discloses a pesticide composition containing spinosad and application of the composition. The composition comprises spinosad (A) and furan tebufenozide (B), wherein the weight ratio of spinosad to furan tebufenozide is (1-50) to (50-1). The composition is prepared into various pesticide formulations by adding components such as an emulsifier, a cosolvent, an antifreezer, a defoamer, a thickener, a stabilizer and a pH regulator, but preferably the composition is prepared into an environment-friendly water-based suspending agent preparation; the composition has a synergistic pesticide effect and can delay pesticide resistance of pests and prevent and control various pests such as delphacidae, aleyrodidae, aphides, thrips, diamondback moths, beet armyworms and mites on crops.

Description

A kind of Pesticidal combination containing pleocidin and uses thereof
Technical field
The present invention relates to technical field of pesticide preparations, be specifically related to a kind of Pesticidal combination containing pleocidin and uses thereof.
Background technology
It is a kind of macrolides Nuisanceless high-efficient biological insecticides extracted in sugared many born of the same parents bacterium (Saccharopolysporaspinosa) zymotic fluid of thorn that pleocidin has another name called multiple killing teichomycin (Spinosad).
Pleocidin is light gray-white crystal, with a kind of smell being similar to slight old earth., 84 DEG C ~ 99.5 DEG C, fusing point A type, 161.5 DEG C ~ 170 DEG C, D type, density 0512g/cm3 (20 DEG C).Solvability in water: be respectively when A type pH is 5,7,9 270,235 and 16mg/], be respectively 28.7,0.332 and 0.053mg/L when D type pH is 5,7,9.In the water aqueous solution, pH is 7.74, to metal and metal ion relatively stable in 28 days.The mode combined by number of ways is in the environment explained, and is mainly photodissociation and microbial degradation.
The mechanism of action of pleocidin is very novel and unique, is different from general macrolides compound, and the chemical constitution of its uniqueness determines the insecticidal mechanism of its uniqueness.Pleocidin exists insect tags and toxicity of ingesting fast, it has the distinctive poisoning symptom of never poison, its mechanism of action is the nervous system by stimulating insect, increase its constitutive activity, cause that the flesh of non-functional shrinks, exhaustion, and with trembling and benumbing, demonstrate nAChR (nChR) and caused acetylcholine (Ach) to extend release reaction by sustained activation.Pleocidin also acts on γ mono-aminobutyric acid (GAGB) acceptor simultaneously, changes the function of GABA gate chloride channel, promotes the raising of its insecticidal activity further.
Pleocidin is a kind of biopesticide of wide spectrum, insecticidal activity is considerably beyond organic phosphor, carbamate, cyclopentadiene and other insecticide, the insect that can effectively control comprises Lepidoptera, diptera and Thysanoptera, also has certain toxic action to the insect of coleoptera, orthoptera, Hymenoptera, Isoptera, Siphonaptera, Dermaptera and some particular types psocopteran simultaneously.
Furan tebufenozide, the insecticide that China has independent intellectual property right, chemistry N mono-(2,3-_7-hydrogen 1 by name, 7-dimethyl. benzofuran .6 mono-formoxyl) a N ' tertiary butyl .N '. (3,5 dimethylbenzoyls) hydrazine, Chinese name furan tebufenozide is a kind of white powdery solids, fusing point: 146.0-148.00C, molten-in organic solvent, water insoluble low toxicity is to fish, honeybee, bird, to the high poison of silkworm; To honeybee low-risk, extremely malicious to silkworm.
Furan tebufenozide, as the N mono-tertiary butyl bishydrazide compounds containing benzofuran ring, has the moulting hormone regulating and controlling effect that bishydrazide compounds generally has.After pests official loyal to his sovereign, there is abnormal reaction of casting off a skin very soon, stop taking food, cast off a skin ahead of time, but cannot complete due to abnormal casting off a skin and cast off a skin, cause larva to dewater and hungry and dead.Stop damage to crops in a few hours after pests official loyal to his sovereign, although the death rate of insect differs, furan tebufenozide to the protected effect of crop both fast and sound! Equally also show higher biologically active.
Summary of the invention
The technical problem to be solved in the present invention is, for existing preparation technique Problems existing, proposes a kind of Pesticidal combination containing pleocidin and uses thereof, improves original preparation technique, improve preventive effect.
Technical solution of the present invention is as follows:
The invention provides one group of Pesticidal combination containing pleocidin, said composition comprises pleocidin and furan tebufenozide, can prevent and treat simultaneously, have synergistic function to the multiple insect pest of crops.
The present invention also additionally provides a kind of suspending agent comprising above-mentioned composition, and percentage by weight consists of:
Above-mentioned all components sum is absolutely
Described wetting dispersing agent can select nonionic surface active agent or anionic surfactant, described non-ionic surface active agent is phenethyl phenol polyethenoxy ether, the rare ether of phenethyl phenol polyethenoxy polyoxy third, alkylphenol polyoxyethylene, alkylphenol polyoxyethylene formaldehyde condensation products, fatty alcohol-polyoxyethylene ether, castor oil polyoxyethylene ether, polystyrene-based phenol formaldehyde resin APEO, phenethyl phenol polyethenoxy ether phosphate, alkylphenol polyoxyethylene phosphate etc., and described anion surfactant is alkyl benzene calcium sulfonate, sodium alkyl benzene sulfonate, C 8~ C 20sodium alkyl sulfate etc.
The optional spent glycol of described antifreezing agent, propane diols, glycerine, polyethylene glycol, sorbierite, urea one of them.
Described defoamer can select organic silicone oil, isooctanol etc.
Described thickener can select xanthans, gum Arabic, carboxymethyl cellulose, CMC, polyvinyl alcohol etc.
Described stabilizing agent can select epoxychloropropane, MPD, tributyl phosphate, sulfonic acid ammonium salt, phosphate, epoxidized vegetable oil etc.
Described PH conditioning agent can select the one in citric acid, lactic acid, glacial acetic acid, hydrochloric acid, phosphoric acid, polyphosphoric acids.
Water of the present invention is running water or ionized water, preferred running water.
Another technical solution of the present invention is, described composition aqueous chemical preparation preparation method comprises the following steps:
Pleocidin and the former medicine of furan tebufenozide and dispersion wetting agent, antifreeze, defoamer, antimicrobial are carried out high speed dispersion according to the ratio of described each component, through sand mill, mixed material is ground to below particle diameter 5um, to rear mixing kettle, add thickener, pH value regulator etc. stir, finished product.
Embodiment
In order to understand essence of the present invention better, describe in detail with instantiation below, but the present invention is not limited thereto.
Embodiment 1
30% pleocidin furan tebufenozide suspending agent preparation, each component proportion by weight:
Its preparation process is as follows: pleocidin and the former medicine of furan tebufenozide and point phenethyl phenol polyethenoxy ether, alkylphenol polyoxyethylene, part water are carried out high speed dispersion 30min according to described ratio, through sand mill, mixed material is ground to below particle diameter 5um, to rear mixing kettle, add ethylene glycol, citric acid, xanthans etc. to stir, finished product.
Experimental example 1
The process taking pleocidin and furan tebufenozide employing embodiment 1 is mixed with by different proportion the pleocidin furan tebufenozide suspending agent that total active ingredient weight percentage is 30%.Concrete ratio sees the following form.
Leaf dipping method is adopted to carry out indoor synergy biologicall test, resistance diamond-back moth is selected to be target pest, often process repetition 3 times, every concentration process 60, calculates virulence regression equation and the lethal concentration of 50 of each medicament antagonism diamond-back moth by probability value method, press the abundant method of Sun Yun calculate co-toxicity coefficient by LC50 value, evaluate mixed effect, usually show three kinds of type of action, i.e. synergy, addition and antagonism, when co-toxicity coefficient (CTC) is greater than 120, there is synergistic effect.
The EC50*100 of the EC50/AB of actual toxicity index ATI (AB)=A; Theoretical toxicity index TTI (AB)=percentage+TI (B) the * B percentage in mixture of TI (A) * A in mixture; Co-toxicity coefficient CTC=ATI (AB)/TTI (AB) * 100, the results are shown in following table:
The toxicity test result of table 1 pleocidin and the composite and single dose antagonism diamond-back moth of furan tebufenozide
As can be seen from Table 1, pleocidin and furan tebufenozide co-toxicity coefficient in ratio range is all greater than 120, illustrates that both all have synergistic function within the scope of this.
Experimental example 2
Leaf dipping method is adopted to carry out indoor synergy biologicall test, selection resistant bollworm is target pest, often process repetition 3 times, every concentration process 60, virulence regression equation and the lethal concentration of 50 of each medicament antagonism diamond-back moth is calculated by probability value method, press the abundant method of Sun Yun by LC50 value and calculate co-toxicity coefficient, the results are shown in following table: table 2 pleocidin and furan tebufenozide is composite and the toxicity test result of single dose antagonism cotton bollworm.
As can be seen from Table 2, pleocidin and furan tebufenozide co-toxicity coefficient in ratio range is all greater than 120, illustrates that both all have synergistic function within the scope of this.
Embodiment 2
20% pleocidin furan tebufenozide suspending agent preparation, each component proportion by weight:
Preparation method is with reference to embodiment 1
Experimental example 3
Control vegetable aphid field control effectiveness test is carried out to embodiment 2, with 20% pleocidin can wet-milling and 20% furan tebufenozide missible oil for contrast medicament, be blank with clear water, after medicine, look into 7 days, 14 days results.Result sees the following form:
Table 3 pleocidin furan tebufenozide compound drug is to the field test results of vegetable aphid.
As shown in Table 3, the invention composition suspending agent of the present embodiment 2 gained all shows good insecticidal activity under dilution 2400 times and 1200 times of concentration, and higher than the insecticidal activity of single dose.Illustrate that the suspending agent antagonism aphid of gained of the present invention has good preventive effect.
Experimental example 4
Carry out preventing and treating the field control effectiveness test of cotton bollworm to embodiment 2, with 20% pleocidin can wet-milling and 20% furan tebufenozide missible oil for contrast medicament, be blank with clear water, after medicine, look into 7 days, 14 days results.Result sees the following form:
Table 4 pleocidin furan tebufenozide compound drug is to the field test results of cotton bollworm.
As shown in Table 4, the invention composition suspending agent of the present embodiment 2 gained all shows good insecticidal activity under dilution 1500 times and 800 times of concentration, and higher than the insecticidal activity of single dose.Illustrate that the suspending agent of gained of the present invention has good preventive effect to cotton bollworm.
Comprehensive above experimental result shows, the composition of pleocidin of the present invention and furan tebufenozide all has good control efficiency to various pests, decrease spraying times and improve control efficiency, and adopt the water base agent type of safety, be the new formulation of environment-friendly high-efficiency, be conducive to applying.

Claims (10)

1., containing a Pesticidal combination for pleocidin, it is characterized in that, described composition comprises pleocidin and furan tebufenozide two kinds of components, and its weight proportion is 1-50:50-1.
2., containing a Pesticidal combination for pleocidin, it is characterized in that, described composition can prevent and treat the various insects such as plant hopper on crops, aleyrodid, aphid, thrips, diamond-back moth, beet armyworm, mite class.
3., containing a Pesticidal combination for pleocidin, it is characterized in that described composition adds the components such as emulsifier, cosolvent, antifreezing agent, defoamer, thickener, stabilizing agent, PH conditioning agent, water and makes the various formulations of pesticide, preferably suspending agent.
4. the suspending agent of composition according to claim 3, it is characterized in that, described emulsifier can select nonionic surface active agent or anionic surfactant, described non-ionic surface active agent is phenethyl phenol polyethenoxy ether, the rare ether of phenethyl phenol polyethenoxy polyoxy third, alkylphenol polyoxyethylene, alkylphenol polyoxyethylene formaldehyde condensation products, fatty alcohol-polyoxyethylene ether, castor oil polyoxyethylene ether, polystyrene-based phenol formaldehyde resin APEO, phenethyl phenol polyethenoxy ether phosphate, alkylphenol polyoxyethylene phosphate etc., described anion surfactant is alkyl benzene calcium sulfonate, sodium alkyl benzene sulfonate, C 8~ C 20sodium alkyl sulfate etc.
5. the suspending agent of composition according to claim 3, is characterized in that, the optional spent glycol of described antifreezing agent, propane diols, glycerine, polyethylene glycol, sorbierite, urea one of them.
6. the suspending agent of composition according to claim 3, is characterized in that, described defoamer can select organic silicone oil, isooctanol etc.
7. the suspending agent of composition according to claim 3, is characterized in that, described thickener can select xanthans, gum Arabic, carboxymethyl cellulose, CMC, polyvinyl alcohol etc.
8. the suspending agent of composition according to claim 3, is characterized in that, described stabilizing agent can select epoxychloropropane, MPD, tributyl phosphate, sulfonic acid ammonium salt, phosphate, epoxidized vegetable oil etc.
9. the suspending agent of composition according to claim 3, is characterized in that, described PH conditioning agent can select the one in citric acid, lactic acid, glacial acetic acid, hydrochloric acid, phosphoric acid, polyphosphoric acids.
10. the suspending agent preparation method of the composition according to claim 3-9, it is characterized in that, pleocidin and the former medicine of furan tebufenozide and dispersion wetting agent, antifreeze, defoamer, antimicrobial are carried out high speed dispersion according to the ratio of described each component, through sand mill, mixed material is ground to below particle diameter 5um, to rear mixing kettle, add thickener, pH value regulator etc. stir, finished product.
CN201410687003.7A 2014-11-25 2014-11-25 Pesticide composition containing spinosad and application of the composition Pending CN104430355A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410687003.7A CN104430355A (en) 2014-11-25 2014-11-25 Pesticide composition containing spinosad and application of the composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410687003.7A CN104430355A (en) 2014-11-25 2014-11-25 Pesticide composition containing spinosad and application of the composition

Publications (1)

Publication Number Publication Date
CN104430355A true CN104430355A (en) 2015-03-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410687003.7A Pending CN104430355A (en) 2014-11-25 2014-11-25 Pesticide composition containing spinosad and application of the composition

Country Status (1)

Country Link
CN (1) CN104430355A (en)

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