CN104383443A - Traditional Chinese medicine composition for treating arrhythmia - Google Patents
Traditional Chinese medicine composition for treating arrhythmia Download PDFInfo
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- CN104383443A CN104383443A CN201410667561.7A CN201410667561A CN104383443A CN 104383443 A CN104383443 A CN 104383443A CN 201410667561 A CN201410667561 A CN 201410667561A CN 104383443 A CN104383443 A CN 104383443A
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Classifications
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- A—HUMAN NECESSITIES
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Abstract
The invention discloses a traditional Chinese medicine composition for treating arrhythmia. The traditional Chinese medicine composition comprises the following raw materials by weight: 8-12g of red ginseng, 55-65g of astragalus membranaceus, 5-7g of coptis chinensis, 30-40g of radix ophiopogonis, 8-12g of schisandra chinensis, 20-30g of radix sophorae flavescentis, 20-30g of root of kudzu vine, 4-6g of panax notoginseng, 10-20g of angelica sinensis, 25-35g of salviae miltiorrhizae, 10-20g of ligusticum wallichii, 8-12g of earthworm, 4-6g of amber, 5-7g of leech, 8-12g of radix curcumae longae, 0.05-0.5g of borneol and 0.1-0.3g of camphor. A Chinese herbal medicine formula is adopted, so that the traditional Chinese medicine composition is available in raw materials, simple in preparation method, good in taking medication effect, low in price, quick in acting, reliable in curative effect, ready to use and free of adverse reaction or side effect, and has the efficacies of warming yang, nourishing the heart and calming the nerves, clearing away the heart-fire and promoting blood circulation to remove blood stasis, dredging collaterals, tonifying qi and restoring the pulses, and the like.
Description
Technical field
The present invention relates to field of Chinese herbal medicine technology, be specifically related to one and be used for the treatment of ARR Chinese medicine composition.
Background technology
Arrhythmia is the unordered excitement of Atrioventricular Conduction and contraction, is also clinical common coronary syndrome.Mostly occur old people and the patient having organic heart disease.Sickness rate becomes positive correlation with the age.The sick position of arrhythmia at the heart, its cardinal symptom is cardiopalmus, dizziness, uncomfortable in chest, weak, breathe hard kank or generation etc.The factor such as common insufficiency of heart-QI, deficiency of heart-blood, declination of heart-YANG, the delay of heart arteries and veins, obstruction of collaterals by blood stasis.Pathogenesis affects the function of heart governing blood and vessels primarily of the deficiency of YIN-blood of deficiency of heart-QI or the heart, causes heart arteries and veins smooth, the venation stasis of blood is stagnant, the heart is become homeless support caused by, its sick position, mainly at the heart, relates to the five internal organs, is the disease of deficiency in origin and excess in superficiality.
Summary of the invention
The object of the present invention is to provide a kind of safe and reliable, what cure rate was high is used for the treatment of ARR Chinese medicine composition.
Technical problem to be solved by this invention realizes by the following technical solutions:
One is used for the treatment of ARR Chinese medicine composition, the medicament be made up of the crude drug of following weight:
Radix Ginseng Rubra 8-12g Radix Astragali 55-65g Rhizoma Coptidis 5-7g 30-40g Radix Ophiopogonis
Fructus Schisandrae Chinensis 8-12g Radix Sophorae Flavescentis 20-30g Radix Puerariae 20-30g Radix Notoginseng 4-6g
Radix Angelicae Sinensis 10-20g Radix Salviae Miltiorrhizae 25-35g Rhizoma Chuanxiong 10-20g Pheretima 8-12g
Succinum 4-6g Hirudo 5-7g Rhizoma Curcumae Longae 8-12g Borneolum Syntheticum 0.05-0.5g
Camphora 0.1-0.3g.
The preferred weight of each crude drug is:
Radix Ginseng Rubra 10g Radix Astragali 60g Rhizoma Coptidis 6g 35g Radix Ophiopogonis
Fructus Schisandrae Chinensis 10g Radix Sophorae Flavescentis 25g Radix Puerariae 25g Radix Notoginseng 5g
Radix Angelicae Sinensis 15g Radix Salviae Miltiorrhizae 30g Rhizoma Chuanxiong 15g Pheretima 10g
Succinum 5g Hirudo 6g Rhizoma Curcumae Longae 10g Borneolum Syntheticum 0.1g
Camphora 0.15g.
Crude drug used by the present invention can be bought from common Chinese shop and obtain, and its specification meets national Chinese crude drug standard.
Usage and dosage:
Above medicine is ground to the powder, cross 120 mesh sieves, put into container and add Oleum Sesami and Camphora, Borneolum Syntheticum furnishing paste, be placed on gauze piece by ointment, make 20cm × 30cm size, thickness is about cave and heart projecting region in the loose note external application wingceltis of 0.5cm, at any time with heat lamp heating, temperature has slight fever sense for degree with skin, each 2 hours, every day 2 times, course for the treatment of Monday.3-5 course for the treatment of, terminate rear check electrocardiogram the course for the treatment of.
Function:
Warming YANG benefit heart and tranquilizing mind, clear away heart-fire blood circulation promoting and blood stasis dispelling, dredging collateral Yiqi and vein recovery.
Cure mainly:
Arrhythmia (being applicable to the Nonorganic lesion getting rid of serious heart failure).
The gas of we's Radix Ginseng, Radix Astragali strongly invigorating primordial QI, the motive, pectoral qi.Gas helps blood, and action character is similar to cardiotonic glycoside therefore be monarch.Radix Ophiopogonis, Fructus Schisandrae Chinensis, Rhizoma Coptidis, succinum supplementing QI for promoting the production of body fluid, the convergence motive, mind calming sedate is minister.Radix Notoginseng, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Puerariae, Rhizoma Chuanxiong, Rhizoma Curcumae Longae, Hirudo, Pheretima play blood circulation and channel invigorating, QI invigorating warming YANG altogether for helping, the merit of multiple arteries and veins mind calming.It is turbid that Camphora Borneolum Syntheticum letter tongue walks to alter to ward off dirtyization, changes turbidly can lead to the seven apertures, loose stagnated fire, and removing obstruction in the collateral to relieve pain, can improve blood flow, reduces myocardial oxygen consumption, and its feature permeability, by force for making, being taken monarch, minister, assistant, medicine are gone directly disease institute.
Pharmaceutical analysis:
Radix Ginseng Rubra
[property of medicine] is pungent, bitter, heat.Very toxic.GUIXIN Liver and kidney spleen channel.
[effect] wind-damp dispelling, antalgic.
[pharmacological action] Radix Ginseng can take off invigorating the spleen to benefit the lung by the multiple arteries and veins of strongly invigorating primordial QI admittedly containing a large amount of saponin, can alleviate smooth muscle spasm, improve immunologic function, and anoxia enduring and anti-stress ability can be improved, improve arterial partial pressure of oxygen and blood oxygen saturation, reduce Peripheral resistance, improve microcirculation.Containing triol, myocardial cell slow calcium channel can be stoped, have protective effect to myocardial ischemia reperfusion injury, and the refractoriness of cardiac muscle is discretely alleviated, to reach arrhythmia.
The Radix Astragali
[property of medicine] is sweet; Tepor.GUIXIN, spleen, lung meridian.
[effect] tonifying Qi and lifting yang, benefit defends consolidating superficial resistance, inducing diuresis to remove edema, holder skin ulcer life.
[pharmacological action] can yang invigorating QI invigorating; recover cardiomyocyte viability; there is an expansion hat tremulous pulse to have normal heart and strengthen heart contraction effect; to poisoning or tired and to sink into the key role of exhaustion more remarkable; it is a kind of non-Folium Digitalis Purpureae inotropic agent; can significantly improve the heart output of qi-deficiency type patients with heart failure and myocardium index, lacking sugared anoxia to heart has direct protective action.
Rhizoma Coptidis
[property of medicine] is bitter, cold, GUIXIN, spleen, stomach, large intestine channel.
[effect] heat clearing and damp drying, eliminating fire and detoxication.
[pharmacological action] can make myocardial cell prolonged refractory period, is beneficial to interrupt reentrant cycle and makes it not easily to be formed, and can improve atrial fibrillation threshold value, extends atrioventricular node and lie refractory stage, slows down conduction, over reach current potential.
Radix Ophiopogonis
[property of medicine] sweet, micro-hardship, is slightly cold.GUIXIN, lung, stomach warp.
[effect] nourishing YIN and moistening the lung, reinforcing stomach reg fluid, clear away heart-fire relieving restlessness.
[pharmacological action] for lack of lung-YIN, and has that scorching dry cough expectorant is sticky, consumptive fever cough etc.Also can be used for deficiency of stomach-YIN or thermal burn stomach-Yin, thirsty and dry pharynx, constipation due to dry stool etc., for diseases such as deficiency of heart-yin.
Fructus Schisandrae Chinensis
[property of medicine] is sour, sweet, warm.Return lung, the heart, kidney channel.
[effect] astringes the lung nourishing kidney, and promote the production of body fluid arresting sweating, arresting seminal emission antidiarrheal, mind tranquilizing and the heart calming.
[pharmacological action], containing cardiotonic glycoside, has heart tonifying decreasing heart rate that atrioventricular is extended, obviously improves myocardial ischemia, improves oxygen-resistant ability, arrhythmia.
Radix Sophorae Flavescentis
[property of medicine] bitter in the mouth, cold in nature, GUIXIN, spleen, kidney channel.
[effect] heat clearing and damp drying, removing toxic substances of dispeling the wind.
[pharmacological action] arrhythmia principle, can strengthen myocardial cell membrane potassium ion, sodium ion passes to system, make cardiac muscle answer muscular to reduce, extend absolute refractory period, therefore control ectopic pacemaker, reduce disease position irritability, control is turned back conduction, has better and controls rhythm of the heart irritability.
Radix Puerariae
[property of medicine] is sweet, pungent, cool.GUIXIN, spleen, stomach warp.
[effect] expelling pathogenic factors from muscles for reducing heat, treating measles, promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal.
[pharmacological action], containing total flavones and puerarin, has obvious coronary artery dilator blood vessel function, can make to enter ischemic region and the increase of non-ischemic region coronary artery blood flow, obviously reduces myocardial oxygen consumption, improves ischemia, also has the effect of beta receptor retardance sample.
Radix Notoginseng
[property of medicine] sweet, micro-hardship, temperature.GUIXIN, liver, spleen, stomach warp.
[effect] blood-activating analgetic, analgesic therapy of invigorating blood circulation.
[pharmacological action], for various internal and external haemorrhage disease, You Yiyou silt person is advisable.This product can be stopped blooding, again can dissipating blood stasis, and drug effect is distinguished, has hemostasis and does not stay silt, blood stasis dispelling and the feature of just not hindering, and can improve the direct blood vessel dilating of coronary circulation, reduce the effect of myocardial oxygen consumption, anti-platelet aggregation and inhibition thrombosis.
Radix Angelicae Sinensis
[property of medicine] is sweet, pungent, warm.Return liver, the heart, spleen channel.
[effect] benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation
[pharmacological action] energy antithrombus formation, reduce myocardial oxygen consumption, arrhythmia has quinidine effect.
Radix Salviae Miltiorrhizae
[property of medicine] is bitter, is slightly cold.GUIXIN, Liver Channel
[effect] activating blood circulation and dissipating phlegm, nourishing blood to tranquillize the mind, effect of removing heat from blood detumescence.
[pharmacological action] can significantly improve coronary flow, and the isolated rabbit ventricular fibrillation caused by electricity irritation can be made to revert to the strong Rythmic contractions characteristic of energy.Decreasing heart rate, improves cardiac muscle and other internal organs circulatory disturbance, blood vessel dilating, eliminates myocardial cell and platelet aggregation.
Rhizoma Chuanxiong
[property of medicine] is pungent, warm.Return liver and gall, pericardium channel.
[effect] blood-activating and qi-promoting, wind-expelling pain-stopping.
The pungent Wen Xiang of [pharmacological action] Rhizoma Chuanxiong alters, and walks and does not keep, both entering blood system, entering edema caused by disorder of QI again.For the dysmenorrhea of the blood stasis stagnation of QI.This product is pungent loose, can invigorate blood circulation, again can circulation of qi promoting, be " in blood gas medicine ", can " lower regulating menstruation water, in open imperial knot." also can be used for headache, rheumatic arthralgia.The pungent temperature rise of this product is fallen apart, energy " the up head ", wind-expelling pain-stopping.Only headache, no matter wind and cold, wind heat, rheumatism, blood deficiency, blood stasis, all can use it with levying compatibility.
Pheretima
[property of medicine] is salty, cold.Return liver, spleen, urinary bladder channel.
[effect] heat clearing away breath phoenix, dredging collateral, relievings asthma, diuresis.
[pharmacological action] for hyperpyrexia convulsion, epilepsy.Blood stagnancy due to deficiency of QI, hemiplegia.Arthromyodynia.For lung-heat asthma.Accumulation of heat in the urinary bladder, dysuria or urine retention obstructed.
Succinum
[property of medicine] is sweet, flat.GUIXIN, urinary bladder channel.
[effect] tranquillizing the mind by relieving convulsion, promoting blood circulation to remove blood stasis, inducing diuresis for treating stranguria syndrome.
[pharmacological action] tranquilizing mind, blood stasis dispelling analgesic therapy.To cholesterol, triglyceride is improved effect.
Hirudo
[property of medicine] is salty, bitter, flat.There is the Slight Cold.GUIXIN, Liver Channel.
[effect] removing blood stasis Xiao wei.
[pharmacological action] can expel wind to dredge collateral, obvious antithrombus formation, and anti-platelet aggregation, improves microcirculation of the heart, and obviously can promote the stable of Atherosclerotic Vessels: Changes Observed during Coronary and disappear.Also have and improve vascular endothelial function, recover coronary artery endothelial cell to nitric oxide production sensitivity, prevent the generation of coronary vasospasm.And energy benefiting QI for activating blood circulation dredging collateral, warm venation, can suppress blood vessel maincenter blood vessel dilating, reduces blood viscosity.
Rhizoma Curcumae Longae
[property of medicine] acrid, bitter, warm.GUIXIN, liver, spleen channel.
[effect] blood-activating and qi-promoting, removing obstruction in the collateral to relieve pain.
[pharmacological action] is adjustable different angles atherosclerosiss such as fat antioxidation, thromboembolism preventing, suppression endothelium smooth muscle cell proliferation, clinical observation shows can soft pulse speckle removing, improves coronary blood confession, increases myocardium oxygen tolerance, obviously alleviate arrhythmia symptom.
Borneolum Syntheticum
[property of medicine] pungent, bitter, be slightly cold.GUIXIN, spleen, lung meridian.
[effect] has one's ideas straightened out refreshment, clearing away heat to alleviate pain.
[pharmacological action] is for excess syndrome of stroke coma.This product has the effect of refreshment of having one's ideas straightened out, and row is partially cold and cool, is the product of waking up the patient from unconsciousness by clearing away heat, should with controlling calentura coma, conjunctival congestion swelling, sore throat aphtha.Swell and ache for skin infection, do not hold back after bursting.Heat-clearing and toxic substances removing, erosion prevention and muscle growing effect.There are the logical seven apertures to fall apart stagnated fire, analgesic effect, blood flow can be improved and reduce myocardial oxygen consumption.
Camphora
[property of medicine] is pungent, heat.Poisonous.GUIXIN, spleen channel.
[effect] takes orally; Having one's ideas straightened out, it is dirty to ward off; External; Dehumidifying parasite killing, warming and odynolysis.
[pharmacological action], for erputive abdominal disease, vomits and diarrhoea, coma.The pungent perfume (or spice) of Camphora is walked to alter, and has causing resuscitation with aromatic drugs and wards off the turbid effect of dirtyization, and row warm in nature falls apart, again can warming and odynolysis.For Jie Xian eczema, pruritus is festered.For tenderness and traumatic injury pain.
In order to verify clinical efficacy, this prescription is tried out at Jieshou City apoplexy sequela institute, and by random selecting wherein 50 routine patients, the course for the treatment of the shortest 1 course for the treatment of, the longest is the 3-5 course for the treatment of.
3) Therapeutic Method
According to instructions of taking of the present invention.
4) efficacy determination: adopt grade III Standard;
1. cure: clinical symptoms disappears substantially, and electrocardiogram recovers normal substantially.
2. take a turn for the better: clinical symptoms obviously alleviates, and ECG change is obviously improved.
3. invalid: clinical symptoms is not improved, electrocardiogram improves without recovering,
Concrete clinical treatment outcome is see table 1.
Table 1
| Number of cases | Recovery from illness | Effectively | Invalid | Effective percentage (%) |
| 50 | 33 | 16 | 1 | 98 |
Medical treatment result: effective percentage 98%, sums up we's treatment arrhythmia, determined curative effect, and can change pathological symptom.
The invention has the beneficial effects as follows: the present invention adopts Chinese herbal medicine formula, material is easy to get, preparation method is simple, and take therapeutic effect good, price is low, there is warming YANG benefit heart and tranquilizing mind, the effects such as clear away heart-fire blood circulation promoting and blood stasis dispelling, dredging collateral Yiqi and vein recovery, instant effect, curative effect is reliable, with system with without obvious adverse reaction and side effect.
Detailed description of the invention
The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.
Embodiment 1
One is used for the treatment of ARR Chinese medicine composition, the medicament be made up of the crude drug of following weight:
Radix Ginseng Rubra 10g Radix Astragali 60g Rhizoma Coptidis 6g 35g Radix Ophiopogonis
Fructus Schisandrae Chinensis 10g Radix Sophorae Flavescentis 25g Radix Puerariae 25g Radix Notoginseng 5g
Radix Angelicae Sinensis 15g Radix Salviae Miltiorrhizae 30g Rhizoma Chuanxiong 15g Pheretima 10g
Succinum 5g Hirudo 6g Rhizoma Curcumae Longae 10g Borneolum Syntheticum 0.1g
Camphora 0.15g.
Crude drug used by the present invention can be bought from common Chinese shop and obtain, and its specification meets national Chinese crude drug standard.
Usage and dosage:
Above medicine is ground to the powder, cross 120 mesh sieves, put into container and add Oleum Sesami and Camphora, Borneolum Syntheticum furnishing paste, be placed on gauze piece by ointment, make 20cm × 30cm size, thickness is about cave and heart projecting region in the loose note external application wingceltis of 0.5cm, at any time with heat lamp heating, temperature has slight fever sense for degree with skin, each 2 hours, every day 2 times, course for the treatment of Monday.3-5 course for the treatment of, terminate rear check electrocardiogram the course for the treatment of.
Function:
Warming YANG benefit heart and tranquilizing mind, clear away heart-fire blood circulation promoting and blood stasis dispelling, dredging collateral Yiqi and vein recovery.
Cure mainly:
Arrhythmia (being applicable to the Nonorganic lesion getting rid of serious heart failure).
Embodiment 2
One is used for the treatment of ARR Chinese medicine composition, the medicament be made up of the crude drug of following weight:
Radix Ginseng Rubra 12g Radix Astragali 55g Rhizoma Coptidis 7g 30g Radix Ophiopogonis
Fructus Schisandrae Chinensis 12g Radix Sophorae Flavescentis 20g Radix Puerariae 30g Radix Notoginseng 4g
Radix Angelicae Sinensis 20g Radix Salviae Miltiorrhizae 25g Rhizoma Chuanxiong 20g Pheretima 8g
Succinum 6g Hirudo 5g Rhizoma Curcumae Longae 12g Borneolum Syntheticum 0.05g
Camphora 0.3g.
Crude drug used by the present invention can be bought from common Chinese shop and obtain, and its specification meets national Chinese crude drug standard.
Usage and dosage:
Above medicine is ground to the powder, cross 120 mesh sieves, put into container and add Oleum Sesami and Camphora, Borneolum Syntheticum furnishing paste, be placed on gauze piece by ointment, make 20cm × 30cm size, thickness is about cave and heart projecting region in the loose note external application wingceltis of 0.5cm, at any time with heat lamp heating, temperature has slight fever sense for degree with skin, each 2 hours, every day 2 times, course for the treatment of Monday.3-5 course for the treatment of, terminate rear check electrocardiogram the course for the treatment of.
Function:
Warming YANG benefit heart and tranquilizing mind, clear away heart-fire blood circulation promoting and blood stasis dispelling, dredging collateral Yiqi and vein recovery.
Cure mainly:
Arrhythmia (being applicable to the Nonorganic lesion getting rid of serious heart failure).
Embodiment 3
One is used for the treatment of ARR Chinese medicine composition, the medicament be made up of the crude drug of following weight:
Radix Ginseng Rubra 8g Radix Astragali 65g Rhizoma Coptidis 5g 40g Radix Ophiopogonis
Fructus Schisandrae Chinensis 8g Radix Sophorae Flavescentis 30g Radix Puerariae 20g Radix Notoginseng 6g
Radix Angelicae Sinensis 10g Radix Salviae Miltiorrhizae 35g Rhizoma Chuanxiong 10g Pheretima 12g
Succinum 4g Hirudo 7g Rhizoma Curcumae Longae 8g Borneolum Syntheticum 0.5g
Camphora 0.1g.
Crude drug used by the present invention can be bought from common Chinese shop and obtain, and its specification meets national Chinese crude drug standard.
Usage and dosage:
Above medicine is ground to the powder, cross 120 mesh sieves, put into container and add Oleum Sesami and Camphora, Borneolum Syntheticum furnishing paste, be placed on gauze piece by ointment, make 20cm × 30cm size, thickness is about cave and heart projecting region in the loose note external application wingceltis of 0.5cm, at any time with heat lamp heating, temperature has slight fever sense for degree with skin, each 2 hours, every day 2 times, course for the treatment of Monday.3-5 course for the treatment of, terminate rear check electrocardiogram the course for the treatment of.
Function:
Warming YANG benefit heart and tranquilizing mind, clear away heart-fire blood circulation promoting and blood stasis dispelling, dredging collateral Yiqi and vein recovery.
Cure mainly:
Arrhythmia (being applicable to the Nonorganic lesion getting rid of serious heart failure).
Medical record 1:
King so-and-so, man, 81 years old, first visit on March 18 in 2010.Patient has hypertension history 10 years.Oral indapamide Treatment of Hypertension.Examine and see that the heart is tired and breathe hard, fatigue and weak, god is clear, and the micro-cyanosis of lip, two lower limb pneumonedema, the tongue stasis of blood is dim, deep-slow pulse.BP21.9/7.2KPr。Heart rate 51 beats/min, rule is neat, and each valve area is not heard and pathologic murmur.Color Sonography shows: left ventricle is grown up.Western medicine diagnose: hypertension 2 grades, hypertensive heart disease (grow up in left room, sinus bradycardia, cardiac function 2 grades).Chinese medical discrimination: heart-yang virtual loss, the heart is become homeless foster.To sum up use the external application of embodiment 1 powder, twice daily, be used in conjunction two weeks, subjective symptoms takes a turn for the better, and continues with three weeks, transference cure.Check ECG core yield 61 beats/min, above method consolidates diagnosis and treatment three months subsequently, and heart rate maintains 60-68 beat/min.After follow up a case by regular visits to 2 years, all are normal.
Note:
Bradyarrhythmia causes cerebral blood flow and PBF to reduce admittedly, thus produces weak, and dizziness and blurred vision even amaurosis such as to be fainted at the symptom.Modern medicine mainly gives 654-2 or Pacemaker implantation treatment, but this patient mostly is old people, and they can not tolerate anticholinergic negative interaction on the one hand, as constipation is very thirsty, and prostate hyperplasia, lethargy etc.Operation risk is high, not easily accepted by the public on the other hand.Easily letter is convenient to use this method, determined curative effect.Bradyarrhythmia is with cardiopalmus, pain uncomfortable in chest, and kank is on behalf of primary symptom, and common gerontal patient, its blood and essence asthenia Yuanyang gradually exhausts, therefore the gas of our Radix Ginseng, Radix Astragali strongly invigorating primordial QI, the motive, pectoral qi.Gas helps blood, and action character is similar to cardiotonic glycoside therefore be monarch.Radix Ophiopogonis, Fructus Schisandrae Chinensis, Rhizoma Coptidis, succinum supplementing QI for promoting the production of body fluid, the convergence motive, mind calming sedate is minister.Radix Notoginseng, Radix Sophorae Flavescentis, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Puerariae, Rhizoma Chuanxiong, Rhizoma Curcumae Longae, Hirudo, Pheretima play blood circulation and channel invigorating, QI invigorating warming YANG altogether for helping, the merit of multiple arteries and veins mind calming.It is turbid that Camphora Borneolum Syntheticum letter tongue walks to alter to ward off dirtyization, changes turbidly can lead to the seven apertures, loose stagnated fire, and removing obstruction in the collateral to relieve pain, can improve blood flow, reduces myocardial oxygen consumption, and its feature permeability, by force for making, being taken monarch, minister, assistant, medicine are gone directly disease institute.
Medical record 2:
Liu, man, 66 years old, first visit in May, 2011.Patient is because of the hidden disease in discontinuity pareordia before 3 years, and cardiopalmus is coronary heart disease and arrhythmia at certain hospital diagnosis, and Multiple Hospitalization treats still recurrent exerbation, tired production, the full outstanding frequency of attackaftermeals.Examine and see: be uncomfortable in chest, feel suffocated, Mental fatigue is slept less, cardiopalmus palpitation and short breath.Pareordia dull pain, time have sweating, purplish tongue, deep and hesitant pulse and short.Electrocardio illustrates: heart rate 89 beats/min, and restrain uneven, ST section moves down, and T ripple is inverted.Dialectical is that qi depression to blood stasis, hypofunction of YANG QI in chest, the heart is become homeless foster.Comprehensive tool feelings, with this method powder external application regulating qi to disperse stagnation, the chest stuffiness relieving activates yang, and medication one week, sensation of oppression and faint pain in the chest subtracts greatly, and cold sweat stops, still has Mental fatigue, palpitation and sleeplessness.Complex clinical continues with ruling by law treatment 5 weeks, and all diseases of patient are eliminated.ECG ST section is without moving down, and T ripple becomes uprightly, and the rhythm of the heart is neat, and following up a case by regular visits to 3 years, all are normal.
Note:
Qi as the commander of blood, the stagnation of QI is blood stasis then, and the resistance of breast sun numbness is the ARR main pathogenesis of arteria coronaria.Radix Ginseng strongly invigorating primordial QI, to play the effect invigorated vital energy and reinforce the heart, the Radix Astragali rises mends pectoral qi, reinforce functional activities of the heart; Fructus Schisandrae Chinensis promotes the production of body fluid arresting sweating, mind tranquilizing and the heart calming, and Fructus Schisandrae Chinensis, containing cardiotonic glycoside, can make chamber prolonged refractory period.Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, clear away heart-fire relieving restlessness, and Radix Ginseng, the Radix Astragali, Radix Ophiopogonis, Fructus Schisandrae Chinensis are monarch, and four medicines share common reinforcing the heart gas, pectoral qi, vigour, and gas fills Hang Mai, and the prosperous then blood of gas, action character is similar to cardiotonic glycoside.Have normal heart and strengthen myocardial contraction effect.For poisoning or tired and key role that is that be hidden in exhaustion is more remarkable, be a kind of non-Folium Digitalis Purpureae inotropic agent, can significantly improve the heart output of deficiency of vital energy patients with heart failure and myocardium index, lacking sugared anoxia to cardiac muscle has direct protective action.Ministerial drug Radix Notoginseng directly can have anticoagulant inhibition thrombosis by blood vessel dilating simultaneously.Radix Salviae Miltiorrhizae can change myocardial contraction, decreased heart rate improves cardiac microcirculation disturbance, and blood vessel dilating eliminates erythrocyte and platelet aggregation, and Hirudo is the good medicine of removing blood stasis, hirudin is the most effective natural anticoagulant collection, and it acts on heparin and has the effect of anticoagulant thrombus.Rhizoma Chuanxiong, pungent Wen Xiang alters, and walks and does not keep, and both enters blood system, enters edema caused by disorder of QI again.Radix Notoginseng, Radix Salviae Miltiorrhizae, Radix Puerariae, Radix Sophorae Flavescentis, be adjuvant drug, 5 QI and blood are taken into account mutually, nourshing blood and promoting blood circulation circulation of qi promoting dissipating blood stasis, and coronary artery dilating increases coronary flow, and anticoagulant improves hypoxia-bearing capability.In addition Borneolum Syntheticum, Camphora lead to the seven apertures for making.The upper comprehensive fastening pathogenic characteristic of all medicines, strengthening vital QI to eliminate pathogenic factors, indicates double controlling.
Medical record 3:
Liu Hong tinkling of pieces of jade female first visit on November 6 in 71 years old 2011.Patient gets along well in cause man for 8 years, feels suddenly to feel oppressed, nervous, impetuous, and insomnia companion pareordia is uncomfortable, dynamic then dizzy, weak, and rear above-mentioned symptom increases the weight of upstairs, is diagnosed as coronary heart disease, arrhythmia to certain hospital's several.This medical main suit is except above-mentioned symptom increases the weight of, and memory obviously goes down.Examine and see painful sickly complexion, body constitution is not good, obviously weak, and tongue lip is dark, and thin fur is yellowish.Deep-thready pulse.Heart rate 59/ point, restrains uneven, and the conduction block of I degree, each valve area is not heard and pathologic murmur.Be diagnosed as coronary heart disease, arrhythmia.Chinese medical discrimination: thoracic obstruction disease, to sum up use powder external applications every day 2 times, be used in conjunction 2 weeks, conscious muscle power is supported, symptom takes a turn for the better, hypermnesia.Continue with 4 weeks, heart rate maintains 64 beats/min.Follow up a case by regular visits to 2 years 8 months, without special discomfort.
Note:
Coronary heart disease and arrhythmia belongs to impediment syndrome.The pathogenesis of morbidity is void, the stasis of blood, stagnant; Void is suffered from a deficiency of the kidney based on the heart, and the stasis of blood is blood.The cause of disease, stagnant is mechanism of qi retardance; Void is this, and stagnant is mark; Void is the cause of disease, and the stasis of blood is pathological product, and stagnant is stasis of blood reason phenomenon, and total pathogenesis is that heart arteries and veins impatency is obstructed.In this loose side, the oxygen of the large reinforcing the heart sun of Radix Ginseng is capable to play the capable arteries and veins of gas; The Radix Astragali benefit motive, logical heart-yang, obviously improves myocardial contraction, increases coronary flow.Rhizoma Chuanxiong, Xin Wen walks to alter, and both enters blood system, enters edema caused by disorder of QI again.Radix Ginseng, the Radix Astragali, Rhizoma Chuanxiong, common heart-yang, Wen Tongxin arteries and veins, walks and does not keep as monarch.Radix Ophiopogonis, Fructus Schisandrae Chinensis, Radix Sophorae Flavescentis, Rhizoma Coptidis, Radix Puerariae, Rhizoma Curcumae Longae, succinum, all medicines, nourish heart and help the moon, moisten and promote the production of body fluid, Tianjin Wang Mai is from filling for minister.Radix Notoginseng, Radix Angelicae Sinensis, Pheretima, Hirudo, promoting blood circulation to remove blood stasis, clots absorbing intestinal stasis relieving, stagnant promoting blood circulation is helped from behavior.Borneolum Syntheticum, Camphora, for making, can lead to the seven apertures, and loose stagnated fire, improves coronary flow, reduces myocardial oxygen consumption.The monarch and his subjects are leading, and assistant makes to assist, and take in common heart-yang, nourish heart cloudy circulation of qi promoting intestinal stasis relieving, and blood circulation promoting and blood stasis dispelling reaches the stasis of blood nature that falls apart and leads to, and unobstructed numbness disease is removed, and follows rule diagnosis and treatment, self-evident.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.
Claims (2)
1. be used for the treatment of an ARR Chinese medicine composition, it is characterized in that, be made up of the crude drug of following weight:
2. one according to claim 1 is used for the treatment of ARR Chinese medicine composition, it is characterized in that, is made up of the crude drug of following weight:
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104906399A (en) * | 2015-06-16 | 2015-09-16 | 郭前进 | Traditional Chinese medicine pills for treating heart disease and preparation method of traditional Chinese medicine pills |
| CN117379490A (en) * | 2023-12-11 | 2024-01-12 | 南昌大学 | Traditional Chinese medicine composition for improving blood oxygen saturation |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1334121A (en) * | 2001-08-31 | 2002-02-06 | 石家庄以岭药业有限公司 | Medicinal composition for restoring cardiac collaterals and its application |
| CN102349985A (en) * | 2011-10-27 | 2012-02-15 | 荣成市崖头美全口腔诊所 | Traditional Chinese medicine composition for treating chronic arrhythmias |
-
2014
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1334121A (en) * | 2001-08-31 | 2002-02-06 | 石家庄以岭药业有限公司 | Medicinal composition for restoring cardiac collaterals and its application |
| CN102349985A (en) * | 2011-10-27 | 2012-02-15 | 荣成市崖头美全口腔诊所 | Traditional Chinese medicine composition for treating chronic arrhythmias |
Non-Patent Citations (2)
| Title |
|---|
| 尤可: "心律失常辨证治疗十法", 《山东中医杂志》 * |
| 祝丹等: "心律失常的中医用药及组方规律探讨", 《陕西中医学院学报》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104906399A (en) * | 2015-06-16 | 2015-09-16 | 郭前进 | Traditional Chinese medicine pills for treating heart disease and preparation method of traditional Chinese medicine pills |
| CN104906399B (en) * | 2015-06-16 | 2018-05-04 | 郭前进 | One kind treats cardiopathic medicine pill and preparation method thereof |
| CN117379490A (en) * | 2023-12-11 | 2024-01-12 | 南昌大学 | Traditional Chinese medicine composition for improving blood oxygen saturation |
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