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CN104383162A - Ointment for infantile eczema - Google Patents

Ointment for infantile eczema Download PDF

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Publication number
CN104383162A
CN104383162A CN201410669775.8A CN201410669775A CN104383162A CN 104383162 A CN104383162 A CN 104383162A CN 201410669775 A CN201410669775 A CN 201410669775A CN 104383162 A CN104383162 A CN 104383162A
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Prior art keywords
ointment
radix
skin
infantile eczema
eczema
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CN201410669775.8A
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王正琦
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Insects & Arthropods (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses an ointment for infantile eczema. The ointment is prepared from the following medicinal raw materials by weight: 20-40 of sophora flavescens ait, 10-25 of densefruit pittany root-bark, 5-10 of angelica dahurica, 10-20 of galla chinensis, 20-40 of aloe, 5-15 of angelica sinensis, 5-10 of panpax notoginseng, 5-10 of poria locos, 20-40 of glycyrrhiza and 5-15 of rose flower. The ointment is prepared by adopting pure natural traditional Chinese medicines, has the advantages of good effect in treating eczema, rapidness in cure and safety without side effect and also has the functions of nourishing and whitening skin, promoting metabolism of the skin and the like.

Description

A kind of ointment for infantile eczema
technical field:
The present invention relates to field of medicaments, particularly a kind of ointment for infantile eczema.
technical background:
Eczema is the modal dermatosis of baby.Baby suffers from eczema and can rise with hoary hair's small red dot on the face, on skin, and eczema also can be suppurated, be seeped water.The hidden danger that eczema is very large to the healthy and safe formation of baby.At present, more weak being not suitable for of the body constitution due to baby is taken medicine, and at treatment infantile eczema, we generally can with smearing some ointment to treat.But these ointment mostly have that therapeutic effect is not good, drug side effect is large, injure infant skin, be unfavorable for the defect that infantile health is grown up.
summary of the invention:
Object of the present invention is exactly defect in order to overcome above-mentioned prior art deficiency and a kind of ointment for infantile eczema provided.
the technical solution used in the present invention is as follows:
For an ointment for infantile eczema, be made up of the raw material of following weight proportion: Radix Sophorae Flavescentis 20-40, Cortex Dictamni 10-25, Radix Angelicae Dahuricae 5-10, Galla Chinensis 10-20, Aloe 20-40, Radix Angelicae Sinensis 5-15, Radix Notoginseng 5-10, Poria 5-10, Radix Glycyrrhizae 20-40, Flos Rosae Rugosae 5-15;
On the basis of such scheme, following further technical scheme can be had: described a kind of ointment for infantile eczema, it is characterized in that the consumption of wherein each crude drug is: Radix Sophorae Flavescentis 30, Cortex Dictamni 15, the Radix Angelicae Dahuricae 8, Galla Chinensis 15, Aloe 25, Radix Angelicae Sinensis 8, Radix Notoginseng 8, Poria 6, Radix Glycyrrhizae 20, Flos Rosae Rugosae 12;
Described ointment can also add Cortex Phellodendri, Borneolum Syntheticum, Folium Artemisiae Argyi;
Described medical ointment prescription can also take orally, can be made into electuary, pill, oral liquid.
Radix Sophorae Flavescentis is bitter, cold.GUIXIN, liver, stomach, large intestine, urinary bladder channel.Inhibitory action is had to dermatophytes and multiple virus.Cure mainly damp and hot dysentery, jaundice, skin eczema, the erosion of vulva wet overworked, the disease such as skin ringworm anthema pruritus, malignant boil, scrofula.
Cortex Dictamni is bitter, cold.Return spleen, stomach warp.There is heat clearing and damp drying, the effect of removing toxic substances of dispeling the wind.Cortex Dictamni has can treat scabies, itchy skin eruption, rheumatic arthralgia, the effects such as mange, aversion to wind, scabies.
Galla Chinensis, sour, puckery, cold in nature, return lung, large intestine, kidney channel.Effect: astringe the lung; Hidroschesis; Astringing intestine to stop diarrhea; Controlling nocturnal emission with astringent drugs; Hemostasis; Removing toxic substances.Be suitable for skin ulcer tinea toxic swelling, the disease such as Skin wet and rotten, eczema.
Radix Notoginseng, warm in nature, sweet and slightly bitter taste, returns liver, stomach.Warp can reducing swelling and alleviating pain, hemostasia and dissipation blood stasis, antiinflammatory action.
The Radix Angelicae Dahuricae, pungent, warm.Attach to the lung and stomach meridians.There is the effects such as antipyretic, analgesia, antiinflammatory.There is certain inhibitory action to body skin bacterium, and have the metabolism promoting skin, delay skin aging, effect of maintaining skin.
Poria, sweet in the mouth, light, property is put down, can dispelling speckles and whitening face, moist skin, can also strengthen immunologic function, blood vessel dilating.
Aloe, bitter, cold.Return lung, large intestine channel.It has the performance making skin contraction, softnessization, moisturizing, antiinflammatory, bleaching.Remove sclerosis, keratinization in addition, improve the effect of scar, little wrinkle, eye pouch, cutis laxa can not only be prevented, skin wet, tender and lovely can also be kept.
Flos Rosae Rugosae, sweet, the micro-hardship of nature and flavor, gas fragrance temperature.Effect: Glycerin, blood circulation promoting, improves the colour of skin, skin quality.
Radix Angelicae Sinensis, nature and flavor, warm in nature, hide sweet, pungent.External has the effect such as skin moistening, maintaining skin, skin nutrition, promotion capillary of skin blood circulation.
Radix Glycyrrhizae, sweet, flat.GUIXIN, lung, spleen, stomach warp.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, carbuncle sore tumefacting virus, cushion toxicity, strong, coordinating the actions of various ingredients in a prescription.
Described Radix Sophorae Flavescentis, Cortex Dictamni have very good curative effect for treatment eczema, are the key medicines for the treatment of eczema.Therefore Radix Sophorae Flavescentis, Cortex Dictamni are the ministerial drug of ointment of the present invention.
Described Galla Chinensis, the Radix Angelicae Dahuricae, Galla Chinensis, Aloe, Radix Angelicae Sinensis, Radix Notoginseng, Flos Rosae Rugosae and monarch drug compatibility have synergism, the curative effect for the treatment of infantile eczema can be made further to strengthen, also have the effect such as skin nutrition, skin whitening, promotion skin metabolism simultaneously.Therefore they are the ministerial drug of Chinese medicine of the present invention.
The effects such as described Radix Glycyrrhizae, Semen Ginkgo can cushion toxicity, strong, blood circulation promoting, the formation of prevention blood clot.Therefore they are the adjuvant of ointment of the present invention.
Described Poria, Radix Glycyrrhizae can be in harmonious proportion the drug side effect of monarch drug, ministerial drug, make herbal nature of the present invention mild, the side effect of cushion, make this ointment be applicable to treat infantile eczema.Therefore they are the adjuvant of ointment of the present invention.
the beneficial effect of this:
The present invention adopts natural Chinese medicines to make, and not only has the advantage that treatment eczema is effective, cure rapidly, have no side effect safely, but also has the effect such as skin nutrition, skin whitening, promotion skin metabolism.
detailed description of the invention one:
For an ointment for infantile eczema, be made up of the raw material of following weight proportion: Radix Sophorae Flavescentis 30 parts, Cortex Dictamni 15 parts, the Radix Angelicae Dahuricae 8 parts, Galla Chinensis 15 parts, Aloe 25, Radix Angelicae Sinensis 8,8 parts, Radix Notoginseng, Poria 6 parts, 20 parts, Radix Glycyrrhizae, 12 parts, Flos Rosae Rugosae;
The ointment preparation method of infantile eczema, is divided into following step:
1, take according to the ratio of weight proportion: Radix Sophorae Flavescentis 30 parts, Cortex Dictamni 15 parts, the Radix Angelicae Dahuricae 8 parts, Galla Chinensis 15 parts, Aloe 25, Radix Angelicae Sinensis 8,8 parts, Radix Notoginseng, Poria 6 parts, 20 parts, Radix Glycyrrhizae, 12 parts, Flos Rosae Rugosae, clean and get ready;
2, the crude drug that step 1 is got ready is put into saucepan, then add 800 parts, clear water, heat 1 hour with high heat until after boiling, then use instead after slow fire decocts 3 hours, stop heating, get ready;
3, the medicinal liquid that step 2 is got ready is filtered, filtering medicinal residues, then add and the moisture in medicinal liquid is evaporated to 45% of medicinal liquid total amount, get ready;
4, step 3 is got ready medicinal liquid to add glycerol, vaseline, adhesion agent etc. and make paste, get ready;
5, step 4 being got ready cream drug is packaged in ointment bottle with 200 grams/bottle, and this ointment being used for infantile eczema has just completed.
During use, only a small amount of ointment uniform application need be suffered from the position of eczema baby.
The present invention adopts natural Chinese medicines to make, not only have treatment eczema effective, cure rapidly, advantage that safety has no side effect, but also can the effectively effect such as nutrition infant skin, whitening infant skin, promotion infant skin metabolism.During use, only a small amount of ointment uniform application need be suffered from the position of eczema baby.

Claims (4)

1., for an ointment for infantile eczema, be made up of the raw material of following weight proportion: Radix Sophorae Flavescentis 20-40, Cortex Dictamni 10-25, Radix Angelicae Dahuricae 5-10, Galla Chinensis 10-20, Aloe 20-40, Radix Angelicae Sinensis 5-15, Radix Notoginseng 5-10, Poria 5-10, Radix Glycyrrhizae 20-40, Flos Rosae Rugosae 5-15.
2. a kind of ointment for infantile eczema according to claim 1, is characterized in that the consumption of wherein each crude drug is: Radix Sophorae Flavescentis 30, Cortex Dictamni 15, the Radix Angelicae Dahuricae 8, Galla Chinensis 15, Aloe 25, Radix Angelicae Sinensis 8, Radix Notoginseng 8, Poria 6, Radix Glycyrrhizae 20, Flos Rosae Rugosae 12.
3. a kind of ointment for infantile eczema according to claim 1, is characterized in that described ointment can also add Cortex Phellodendri, Borneolum Syntheticum, Folium Artemisiae Argyi.
4. a kind of ointment for infantile eczema according to claim 1, is characterized in that described medical ointment prescription can also take orally, can be made into electuary, pill, oral liquid.
CN201410669775.8A 2014-11-21 2014-11-21 Ointment for infantile eczema Pending CN104383162A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104825594A (en) * 2015-04-25 2015-08-12 孙村镇中药材种植技术协会 External use traditional Chinese medicine for treating infantile eczema
CN106806558A (en) * 2015-11-30 2017-06-09 石家庄以岭药业股份有限公司 A kind of beautifying face and moistering lotion health-care medicine pillow
CN107041860A (en) * 2017-03-02 2017-08-15 广东省阳春市信德生物科技发展有限公司 A kind of infant skin care cream
CN113318048A (en) * 2021-06-16 2021-08-31 广东快女生物技术有限公司 Female private mask formula with skin moisturizing effect
CN115282168A (en) * 2022-08-30 2022-11-04 马应龙大健康有限公司 Soothing moisturizer for relieving infantile eczema symptom and preparation method and application thereof

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WO1999024577A1 (en) * 1997-11-10 1999-05-20 Statens Serum Institut NUCLEIC ACID FRAGMENTS AND POLYPEPTIDE FRAGMENTS DERIVED FROM $i(M. TUBERCULOSIS)
CN101721594A (en) * 2008-10-27 2010-06-09 成都永康制药有限公司 Chinese medicinal ointment with antibacterial and antipruritic effects and preparation method thereof
CN101564420A (en) * 2009-06-04 2009-10-28 成都拜特尔药业有限公司 Chinese medicinal herb composition for treating skin disease

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104825594A (en) * 2015-04-25 2015-08-12 孙村镇中药材种植技术协会 External use traditional Chinese medicine for treating infantile eczema
CN106806558A (en) * 2015-11-30 2017-06-09 石家庄以岭药业股份有限公司 A kind of beautifying face and moistering lotion health-care medicine pillow
CN107041860A (en) * 2017-03-02 2017-08-15 广东省阳春市信德生物科技发展有限公司 A kind of infant skin care cream
CN113318048A (en) * 2021-06-16 2021-08-31 广东快女生物技术有限公司 Female private mask formula with skin moisturizing effect
CN115282168A (en) * 2022-08-30 2022-11-04 马应龙大健康有限公司 Soothing moisturizer for relieving infantile eczema symptom and preparation method and application thereof
CN115282168B (en) * 2022-08-30 2024-05-31 马应龙大健康有限公司 Soothing skin cream for relieving infant eczema symptoms and preparation method and application thereof

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Application publication date: 20150304