CN104356656B - A kind of dissection cake wax and preparation method thereof - Google Patents

Abstract

The invention provides an anatomical wax dish. The components include: 7-20 microcrystalline wax, 14-31 paraffin wax, 6-17 ozokerite wax, 7-15 polybutene, 14-28 beeswax, and polybutene in parts by mass. Ethylene wax 7-12, calcified rosin 3-11, castor oil 2-8, liquid paraffin 4-11, butyl rubber 2-9, white petrolatum 2-5, white oil 2-6. The surface of the wax plate made according to the formula of the present invention is smooth, the toughness is moderate, and it is not easy to be brittle; after being pierced with an anatomical needle or an insect needle for many times, there is no wax residue and the pinholes are easy to restore; the wax plate has no peculiar smell and is easy to reshape; Under ambient temperature (0℃～50℃), it has low-temperature toughness, impact resistance, and is not easy to be brittle; high temperature is not easy to soften and become sticky, and has no volatile odor. The dissecting wax dish of the present invention has simple manufacturing method, stable performance of the wax dish, and can meet the anatomical needs of biological and medical experiment specimens under different temperature environments.

Description

A kind of dissecting wax plate and its manufacturing method

technical field

The invention relates to the technical fields of biology and medicine, in particular to a wax dish used for biology and medical anatomy and a manufacturing method thereof.

Background technique

Wax disc is a commonly used auxiliary tool in biological and medical anatomy experiments. Its main purpose is to provide a landing matrix for biological and medical tissues so that the tissues or organs can be exposed or present the required shape or orientation, so as to facilitate observation or recording of image data. Finally, it is beneficial to the anatomical operation and collects the best structural characteristics and morphological images of the tested materials. At present, there is no commercialized wax dish or product with the same function. Biomedical anatomy operations still use traditional wax dishes, which are directly poured into the shallow dish enamel after the paraffin wax is melted. Due to the hard and brittle texture of this kind of traditional wax plate, the bulky shape, it is difficult to pierce the anatomical needle. Difficult, easy to break and disintegrate.

Contents of the invention

In order to solve the above problems, the object of the present invention is to provide an anatomical wax dish used in biology and medicine and its manufacturing method. The prepared anatomical wax dish has toughness and will not be brittle under the environment of 10-45°C.

In order to achieve the above object, a kind of dissection wax dish provided by the invention, its component contains by mass parts:

Microcrystalline wax 7-20, paraffin wax 14-31, ozokerite 6-17, polybutene 7-15, beeswax 14-28, polyethylene wax 7-12, calcified rosin 3-11, castor oil 2-8, liquid Paraffin wax 4-11, butyl rubber 2-9, white petrolatum 2-5, white oil 2-6.

The preferred component mass parts contain:

Microcrystalline wax 9~14, paraffin wax 15~23, ozokerite 8~14, polybutene 8~11, beeswax 17~22, polyethylene wax 8~11, calcified rosin 4~7, castor oil 2~4, liquid Paraffin wax 5-8, butyl rubber 3-7, white petrolatum 2-3, white oil 2-4.

A method for making a biomedical dissection wax dish provided by the invention comprises the following steps:

1) Mix microcrystalline wax and paraffin wax according to the proportion, heat slowly to melt, then heat up to 120-140°C, add ozokerite wax and polyethylene wax, and stir continuously to melt all the particles;

2) Lower the temperature of the above melt to 90-100°C, add beeswax to melt at a constant temperature and become liquid, then add polybutene and calcified rosin, and stir slowly; then add white vaseline, white oil, and castor oil in sequence, and stir fully at constant temperature ;

3) Reheat the above-mentioned fully stirred materials to 120-140°C, add butyl rubber and liquid paraffin in turn, and stop heating after stirring evenly;

4) Cool the material obtained in step 3) to 70-90°C, keep it warm for 30-50 minutes, filter it through a 100-mesh copper mesh, put it in a petri dish, and cool it at room temperature to shape it.

The technical solution provided by the invention may also contain one or more of the following nanoscale fillers: 2-5 kaolin, 1-3 diatomite, and 1-3 raw gypsum. The filler has stable chemical properties and does not contain harmful substances. Adding it to the anatomical wax dish can improve adhesion, increase toughness, prevent embrittlement, impact resistance and other performances.

A method for making a biomedical dissection wax dish provided by the invention comprises the following steps:

1) Mix microcrystalline wax and paraffin wax according to the proportion, heat slowly to melt, then heat up to 120-140°C, add ozokerite wax and polyethylene wax, and stir continuously to melt all the particles;

2) Lower the temperature of the above melt to 70-90°C, add beeswax to melt at a constant temperature and become liquid, then add polybutene and calcified rosin, and stir slowly; then add white vaseline, white oil, and castor oil in sequence, and stir fully at constant temperature ;

3) Reheat the above-mentioned fully stirred materials to 120-140°C, add butyl rubber and liquid paraffin in turn, and stop heating after stirring evenly;

4) Cool the material obtained in step 3) to 80-90°C, add nano-scale fillers, and stir fully in the same direction;

5) Slowly cool the material obtained in step 4 to 70-90°C, keep it warm for 30-50 minutes, filter it through a 100-mesh copper mesh, put it in a petri dish, and cool it at room temperature to shape it.

Compared with the prior art, the advantages and effects of the present invention: 1. The surface of the wax plate made according to the formula is smooth, the toughness is moderate and not easy to be brittle; 2. There is no wax residue and the pinholes are easy to restore after repeated pricking with dissecting needles or insect needles ;3 The wax plate has no peculiar smell and is easy to reshape; 4 Under extreme ambient temperature (0 ℃ ~ 50 ℃), it has low temperature toughness, impact resistance, and is not easy to be brittle; high temperature is not easy to soften and become sticky, and has no volatile odor.

detailed description:

Example 1

Component ratio: microcrystalline wax 9g, paraffin wax 19g, ozokerite: 9g, polybutene 8g, beeswax 18g, polyethylene wax 9g, calcified rosin 4g, castor oil 3g, liquid paraffin 6g, butyl rubber 5g, white petrolatum 3g , white oil 2g, kaolin 2g, diatomaceous earth 1.5g, raw gypsum 1.5g.

The preparation method steps are as follows:

1) Mix the microcrystalline wax and paraffin wax according to the proportion, heat slowly to melt, then raise the temperature to 130°C, add ozokerite wax and polyethylene wax, and keep stirring to melt all the particles;

2) Cool the above melt to 90°C, add beeswax to melt at a constant temperature and become liquid, then add polybutene and calcified rosin, and stir slowly; then add white vaseline, white oil, and castor oil in sequence, and stir fully at constant temperature;

3) Reheat the above-mentioned fully stirred materials to 120°C, add butyl rubber and liquid paraffin in turn, and stop heating after stirring evenly;

4) Cool the material obtained in step 3) to 90°C, add diatomaceous earth, kaolin and raw gypsum, and stir fully in the same direction to avoid bubbles in the liquid;

5) Slowly cool the material obtained in step 4 to 80°C, heat it for 40 minutes, filter it through a 100-mesh copper mesh, place it in a petri dish with a diameter of 10-15cm and a height of 1-1.5cm, and cool it at room temperature to shape it.

Low-temperature impact performance test: The wax plate made according to the above formula and preparation technology was placed in the refrigerator at -4°C for 1 hour, then taken out, suspended and released from a distance of 1.5m from the ground, and allowed to fall freely to the ground covered with ordinary floor tiles, and the wax was observed. Plate condition: There are impact marks on the edge of the wax plate, but the wax plate has not been broken or disintegrated, no debris, and no deformation as a whole; use the national standard 3# insect needle to penetrate the wax plate for more than 0.5mm, the wax plate is moderately soft, pull out the insect needle There is no sticky wax shavings on the rear needle body, and no wax shavings on the surface of the wax plate.

High-temperature impact performance test: The wax plate made according to the above formula and preparation technology was baked in a temperature-controlled oven at 48°C for 1 hour and then taken out. The wax plate did not soften or deform; it fell freely to the ground from a distance of 1.5m from the indoor floor. There are impact marks on the edge of the wax plate and local slight deformation, but the wax plate as a whole is not kept flat; there is no liquid exudate on the surface of the wax plate, and there is no volatile odor. The national standard 3# insect is used to pierce the wax plate for more than 0.5mm, and it is soft The degree is moderate, the needle hole is not loose when the end of the insect needle is moved, and there is no sticking wax on the needle body after the insect needle is pulled out.

Wax plate reshaping experiment: The wax plate made by the above formula and preparation technology was tried out at room temperature for 2 months from time to time, during which time the wax plate was used for dissection of animal and plant specimens, and insect needles of different specifications were used to puncture hundreds of times . Heat and melt the used wax dish in a beaker filled with tap water, filter it through an 80-mesh copper mesh and cool it at room temperature, take out the formed wax dish from the beaker, and then perform the above-mentioned high and low temperature impact experiments. The wax discs perform the same.

Example 2

Component ratio: microcrystalline wax 9g, paraffin wax 22g, ozokerite: 8g, polybutene 9g, beeswax 20g, polyethylene wax 9g, calcified rosin 4g, castor oil 2g, liquid paraffin 7g, butyl rubber 4g, white petrolatum 3g , kaolin 2g, diatomaceous earth 1g.

Preparation method and test experiment are the same as embodiment 1.

Example 3

Component ratio: microcrystalline wax 12g, paraffin wax 16g, ozokerite 12g, polybutene 9g, beeswax 22g, polyethylene wax 8g, calcified rosin 3g, castor oil 3g, liquid paraffin 5g, butyl rubber 4g, white petrolatum 3g, Kaolin 2g, raw gypsum 1g.

Preparation method and test experiment are the same as embodiment 1.

Example 4

Component ratio: microcrystalline wax 15g, paraffin wax 15g, ozokerite 10g, polybutene 11g, beeswax 17g, polyethylene wax 7g, calcified rosin 5g, castor oil 4g, liquid paraffin 8g, butyl rubber 4g, white petrolatum 2g, Diatomaceous earth 1g, raw gypsum 1g.

Preparation method and test experiment are the same as embodiment 1.

Example 5

Microcrystalline wax 7g, paraffin wax 30g, ozokerite: 6g, polybutene 7g, beeswax 18g, polyethylene wax 11g, calcified rosin 7g, liquid paraffin 5g, butyl rubber 5g, white petrolatum 2g, kaolin 2g or raw gypsum 2g.

The preparation method and test experiment are the same as in Example 1.

Example 6

Microcrystalline wax 7g, paraffin wax 31g, ozokerite: 6g, polybutene 7g, beeswax 28g, polyethylene wax 7g, calcified rosin 3g, liquid paraffin 4g, butyl rubber 2g, white petrolatum 3g, diatomaceous earth 2g or raw gypsum 2g .

Preparation method and test experiment are the same as embodiment 1.

Example 7

A wax dish for anatomy of biological and medical experiment specimens, the composition ratio: microcrystalline wax 9g, paraffin wax 19g, ozokerite: 9g, polybutene 8g, beeswax 18g, polyethylene wax 9g, calcified rosin 4g, castor oil 3g, Liquid paraffin 6g, butyl rubber 5g, white vaseline 3g, white oil 2g,

Preparation:

1) Mix the microcrystalline wax and paraffin wax according to the proportion, heat slowly to melt, then raise the temperature to 130°C, add ozokerite wax and polyethylene wax, and keep stirring to melt all the particles;

2) Cool the above melt to 90°C, add beeswax to melt at a constant temperature and become liquid, then add polybutene and calcified rosin, and stir slowly; then add white vaseline, white oil, and castor oil in sequence, and stir fully at constant temperature;

3) Reheat the above-mentioned fully stirred materials to 120°C, add butyl rubber and liquid paraffin in turn, and stop heating after stirring evenly;

4) Cool the material obtained in step 3) to 80° C., heat it for 40 minutes, filter it through a 100-mesh copper mesh, place it in a petri dish, and cool it at room temperature to shape it.

Test experiment is the same as embodiment 1.

These tests confirm that: the anatomical wax dish made by the formula and preparation technology of the present invention has good low-temperature toughness and impact resistance at a certain vertical height; it has the advantages of high temperature resistance, no deformation, and stable performance at room temperature in the actual operating environment. ; It is convenient for heating and reshaping after surface deformation caused by multiple punctures, and can better adapt and meet the needs and applications in teaching, scientific research, and production practice.

The specific examples described above have further described the purpose, technical operation scheme, and advantageous effects of the present invention in detail. It should be pointed out that the above performance description is only a specific example of the present invention, and does not limit the scope of protection related to the formulation optimization and production technology of the present invention. Any formulation improvements, equivalent replacements, and sequence adjustments should be included within the protection scope of the present invention.

Claims (1)

1. An anatomical wax dish is characterized in that the composition ratio and the preparation method of the wax dish: The components are counted in parts by mass: 9-14 microcrystalline wax, 15-23 paraffin wax, 8-14 ozokerite wax, 8-11 polybutene, 17-22 beeswax, 8-11 polyethylene wax, and 4 calcified rosin ～7, castor oil 2～4, liquid paraffin 5～8, butyl rubber 3～7, white vaseline 2～3, white oil 2～4, nanoscale filler 2-8; Described nanoscale filler is kaolin, One, two or three of diatomaceous earth and raw gypsum; The manufacturing method of described wax dish, comprises the following steps: 1) Mix microcrystalline wax and paraffin wax according to the proportion, heat slowly to melt, then heat up to 120-140°C, add ozokerite wax and polyethylene wax, and stir continuously to melt all the particles; 2) Lower the temperature of the above melt to 70-90°C, add beeswax to melt at a constant temperature and become liquid, then add polybutene and calcified rosin, and stir slowly; then add white vaseline, white oil, and castor oil in sequence, and stir fully at constant temperature ; 3) Reheat the above-mentioned fully stirred materials to 120-140°C, add butyl rubber and liquid paraffin in turn, and stop heating after stirring evenly; 4) Cool the material obtained in step 3) to 80-90°C, add nano-scale fillers, and stir fully in the same direction; 5) Slowly cool the material obtained in step 4 to 70-90°C, keep it warm for 30-50 minutes, filter it through a 100-mesh copper mesh, put it in a petri dish, and cool it at room temperature to shape it.