CN104352737A - Traditional Chinese medicinal preparation for treating rheumatic low back and leg pain - Google Patents

Abstract

The invention discloses a traditional Chinese medicinal preparation for treating rheumatic low back and leg pain. The traditional Chinese medicinal preparation for treating the rheumatic low back and leg pain is prepared from the following medicinal materials in parts by weight: 60 parts of semen strychni, 7 parts of scorpio, 7 parts of earthworm, 7 parts of ground beetle, 5 parts of deer-horn glue, 3 parts of liquorice, 1 part of cinnabar, 15 parts of eel blood, 5 parts of Japanese peristrophe herb, 6 parts of allium cyaneum regel, 8 parts of rabdosia ternifolia, 4 parts of cleavers and 3 parts of doronicum altaicum pallas. Clinical experiments prove that appropriate medicinal materials and a ratio thereof are selected, the traditional Chinese medicinal preparation for treating the rheumatic low back and leg pain has the effects of dispelling wind and removing cold, activating meridians to stop pain and conditioning functions, and the traditional Chinese medicinal preparation for treating the rheumatic low back and leg pain is high in curative ratio and safe and produces no toxic or side effect when used for treating the rheumatic low back and leg pain.

Description

A kind of Chinese medicine preparation for the treatment of rheumatic lumbago and scelalgia disease

Technical field

The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for the treatment of rheumatic lumbago and scelalgia disease.

Background technology

Moist lumbago and skelalgia disease is commonly encountered diseases, the frequently-occurring disease in the vast rural area of China.Be common with person in middle and old age, develop to Young Patients in recent years.Cardinal symptom drops to main clinical manifestation with the knee joint risen morning, the stiff pain of joint of lumbar vertebra, limitation of activity, work.Clinically to the treatment of this disease, generally based on doctor trained in Western medicine, but most medicament drug effect does not show, and the therapeutic effect for rheumatic lumbago and scelalgia disease is not remarkable.

Summary of the invention

The present invention aims to provide a kind of Chinese medicine preparation for the treatment of rheumatic lumbago and scelalgia disease, it selects medical material compatibility suitable, meet Chinese medicine and modern medicine study theory, there is effect of expelling wind and cold, removing obstruction in the collateral to relieve pain, conditioning function, the high and safe without toxic side effect of the sick cure rate for the treatment of rheumatic lumbago and scelalgia.

In order to achieve the above object, the present invention is by the following technical solutions: a kind of Chinese medicine preparation for the treatment of rheumatic lumbago and scelalgia disease, it is characterized in that, be prepared from by the medical material of following weight proportion: Semen Strychni 60 parts, Scorpio 7 parts, Pheretima 7 parts, eupolyphage sece steleophaga 7 parts, Colla cornus cervi 5 parts, 3 parts, Radix Glycyrrhizae, 1 part, Cinnabaris, Sanguis Monopteri albi 15 parts, Herba Peristrophes 5 parts, white wolf Herba Alii fistulosi 6 parts, SANYE besom 8 parts, Herba Galii Teneri 4 parts, A Ertai doronicum stenoglossum (doronicum) 3 parts.

2. treat the preparation method of the Chinese medicine preparation of rheumatic lumbago and scelalgia disease for one kind, it is characterized in that, comprise the steps: that Semen Strychni, Scorpio, Pheretima, eupolyphage sece steleophaga, Radix Glycyrrhizae, A Ertai doronicum stenoglossum (doronicum), Herba Peristrophes, white wolf Herba Alii fistulosi, SANYE besom, Herba Galii Teneri are put into container by (1), add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) Colla cornus cervi, Cinnabaris, Sanguis Monopteri albi are put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of rheumatic lumbago and scelalgia disease of the present invention.

The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:

Semen Strychni [source] this product is the dry mature seed of loganiaceae plant Semen Strychni.[nature and flavor] are bitter, temperature; Very toxic.[return through] returns liver, spleen channel.[function cures mainly] removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.For rheumatoid arthritis stubborn, paralysis and numbness, injury from falling down, ulcer sore pain; Poliomyelitis sequela, rheumatoid arthritis.

The dry body of Scorpio [source] Buthidae animal Scorpio.[nature and flavor] are pungent, flat; Poisonous.[return through] returns Liver Channel.[function cures mainly] endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.

Pheretima [source] this product is the dry body of Ju Yin section animal Pheretima aspergillum.[nature and flavor] are salty, cold.[return through] returns liver, spleen, urinary bladder channel.[function cures mainly] heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.

The male Scorpio that eupolyphage sece steleophaga [source] is Corydiidae insecticide eupolyphoge sinensis or Ji Lian section insecticide opishoplatia orientalis Brumister.[nature and flavor] are salty, cold, poisonous.[return through] enters the heart, liver, spleen three warp.[function cures mainly] removing blood stasis, removing mass, dredging collateral, reason wound.Control lump in the abdomen, amenorrhea due to stagnation of blood, postnatal blood stasis is suffered from abdominal pain, traumatic injury, swollen and rigid tongue, congenital deformity of the tongue.

Colla cornus cervi [source] for Cornu Cervi endure through decocting, the concentrated solid gum made.[nature and flavor] are sweet, salty, temperature.[return through] returns kidney, Liver Channel.[function cures mainly] temperature compensation Liver and kidney, beneficial intensive culture blood.

Radix Glycyrrhizae [nature and flavor] is sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

Cinnabaris [source] this product is sulfide-based mineral cinnabar race cinnabar, main Containing Sulfur hydrargyrum (HgS).After excavating, choose pure person, with the impurity of Magnet exhaustion iron content, then wash in a pan roguing stone and silt with water.[nature and flavor] are sweet, are slightly cold; Poisonous.[return through] GUIXIN warp.[function cures mainly] clears away heart-fire relieving convulsion, removing toxic substances of calming the nerves.For palpitation and being susceptible to fright, insomnia and dreamful sleep, epilepsy is gone mad, infantile convulsion, blurring of vision, aphtha, sore throat, sore swollen toxin.

The blood that Sanguis Monopteri albi [source] is He Sai section animal Monopterus albus (Zuiew).[nature and flavor] salty in the mouth; Warm in nature.[return through] liver; Kidney channel.[function cures mainly] dispelling wind and removing obstruction in the collateral; Invigorate blood circulation; Tonifying YANG; Removing toxic substances; Improving eyesight.The main export eye oblique; injuries; impotence; Earache; tinea; anal fistula; conjunctivitis.

Herba Peristrophes [source] medical material Ji Yuan: be root or the herb of feverfew chrysanthemum leaf Radix Notoginseng.[nature and flavor] sweet in the mouth; Micro-hardship; Warm in nature.[function cures mainly] stops blooding; Dissipating blood stasis; Reducing swelling and alleviating pain; Heat-clearing and toxic substances removing.Main haematemesis; Epistaxis; Spitting of blood; Have blood in stool; Metrorrhagia; Traumatic hemorrhage; Dysmenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Traumatic injury; Rheumatalgia; Carbuncle sore cellulitis furuncle; Worm venom.

The blue Jacob's ladder of white wolf Herba Alii fistulosi [source] Liliaceae, with all herbal medicine.[nature and flavor] are pungent, temperature.[function cures mainly] dispersing wind-cold, activates yang, stomach invigorating.Cure mainly wind and cold diseases caused by exogenous pathogenic factor, YIN-cold is suffered from abdominal pain, cold extremities faint pulse, traumatic injury.

SANYE besom [source] Labiatae Rabdosia plant wheel blade Herba Rabdosiae glaucocalycis, with all herbal medicine.[nature and flavor] are bitter, micro-pungent, cool.[function cures mainly] clearing away heat-damp and promoting diuresis, removing toxic substances.For flu, bronchitis, tonsillitis, pharyngolaryngitis, toothache, enteritis, dysentery, icterohepatitis, acute nephritis, cystitis; Venom is controlled in external.

The herb of Herba Galii Teneri [source] Maguireothamnus speciosus Herba Galii Teneri.[nature and flavor] bitter in the mouth, property is put down.[function cures mainly] assists day clearly, cures the wound, hemostasis, synthetism, diuresis.Cure mainly jaundice, intestinal acute diseases such as cholera and sunstroke, ache of the spinal column, urethra causalgia, wart, acne, fracture, wound.

A Ertai doronicum stenoglossum (doronicum) [source] Compositae A Ertai doronicum stenoglossum (doronicum), with all herbal medicine.[nature and flavor] are sweet, bitter, temperature.[function cures mainly] expelling phlegm for arresting cough, the chest stuffiness relieving promoting the circulation of QI.Cure mainly phlegm dyspnea cough.The present invention compared with prior art, has following beneficial effect:

1, Chinese medicine preparation of the present invention has effect of expelling wind and cold, removing obstruction in the collateral to relieve pain, conditioning function, the high and safe without toxic side effect of the sick cure rate for the treatment of rheumatic lumbago and scelalgia.Be monarch drug with Semen Strychni in side, it has the effect of removing obstruction in the collateral to relieve pain, then with insects medical herbs for minister, provide its search wind pick heresy can and blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, migratory arthralgia pain relieving; Mutually help benefit with A Ertai doronicum stenoglossum (doronicum), Herba Peristrophes, white wolf Herba Alii fistulosi, SANYE besom, Herba Galii Teneri etc. again, finally share Colla cornus cervi, Sanguis Monopteri albi with dispelling wind and removing obstruction in the collateral, temperature compensation Liver and kidney, both can expelling wind and cold, removing obstruction in the collateral to relieve pain, again can alleviating pain, mitigation symptoms, improves function, is treating both the principal and secondary aspects of a disease.

2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take: Semen Strychni 60 grams, Scorpio 7 grams, Pheretima 7 grams, eupolyphage sece steleophaga 7 grams, Colla cornus cervi 5 grams, 3 grams, Radix Glycyrrhizae, 1 gram, Cinnabaris, Sanguis Monopteri albi 15 grams, Herba Peristrophes 5 grams, white wolf Herba Alii fistulosi 6 grams, SANYE besom 8 grams, Herba Galii Teneri 4 grams, A Ertai doronicum stenoglossum (doronicum) 3 grams, be prepared by following processing step: Semen Strychni, Scorpio, Pheretima, eupolyphage sece steleophaga, Radix Glycyrrhizae, A Ertai doronicum stenoglossum (doronicum), Herba Peristrophes, white wolf Herba Alii fistulosi, SANYE besom, Herba Galii Teneri are put into container by (1), add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) Colla cornus cervi, Cinnabaris, Sanguis Monopteri albi are put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of rheumatic lumbago and scelalgia disease of the present invention.

Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 20 days, be 1 course for the treatment of, take 2 ~ 3 courses for the treatment of continuously.

Clinical data:

1, case selection:

As the Chinese medicine preparation for the treatment of rheumatic lumbago and scelalgia disease, select the routine clinical observation of rheumatic lumbago and scelalgia patient 78 of diagnosis and treatment since 2010.Patient condition contains chronic rheumatic arthritis, rheumatoid arthritis, lumbago and backache, rheumatic myositis etc.Patient is divided into treatment group and matched group two groups at random, treatment group 39 example, matched group 39 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.

2, medicament selection:

Treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 1, oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 20 days, be 1 course for the treatment of, take 1-3 the course for the treatment of continuously.

Matched group ibuprofen 400 mg, 3 times/day, oral meal, 20 days courses for the treatment of, treats 3 courses for the treatment of continuously.

3, efficacy determination:

(1) cure: clinical symptom disappearance, walking freely;

(2) take a turn for the better: clinical symptom relief, but walking fashion has a little pain;

(3) do not heal: before and after treatment, clinical symptoms is without improvement.

4, result:

Select in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, cure 22 examples, take a turn for the better 15 examples, and do not heal 2 examples, cure rate 56.4%, total effective rate 94.9%.

Cure 13 examples in matched group, take a turn for the better 20 examples, and do not heal 6 examples, cure rate 33.3%, total effective rate 84.6%.

Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.

Obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.

Claims (2)

1. treat the Chinese medicine preparation of rheumatic lumbago and scelalgia disease for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: Semen Strychni 60 parts, Scorpio 7 parts, Pheretima 7 parts, eupolyphage sece steleophaga 7 parts, Colla cornus cervi 5 parts, 3 parts, Radix Glycyrrhizae, 1 part, Cinnabaris, Sanguis Monopteri albi 15 parts, Herba Peristrophes 5 parts, white wolf Herba Alii fistulosi 6 parts, SANYE besom 8 parts, Herba Galii Teneri 4 parts, A Ertai doronicum stenoglossum (doronicum) 3 parts.

2. treat the preparation method of the Chinese medicine preparation of rheumatic lumbago and scelalgia disease for one kind, it is characterized in that, comprise the steps: that Semen Strychni, Scorpio, Pheretima, eupolyphage sece steleophaga, Radix Glycyrrhizae, A Ertai doronicum stenoglossum (doronicum), Herba Peristrophes, white wolf Herba Alii fistulosi, SANYE besom, Herba Galii Teneri are put into container by (1), add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) Colla cornus cervi, Cinnabaris, Sanguis Monopteri albi are put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of rheumatic lumbago and scelalgia disease of the present invention.