CN104258278A - Gushangling (for bone injury) spray - Google Patents
Gushangling (for bone injury) spray Download PDFInfo
- Publication number
- CN104258278A CN104258278A CN201410489241.7A CN201410489241A CN104258278A CN 104258278 A CN104258278 A CN 104258278A CN 201410489241 A CN201410489241 A CN 201410489241A CN 104258278 A CN104258278 A CN 104258278A
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- gushangling
- spray
- rhizoma
- bone wound
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Abstract
The invention discloses a Gushangling (for bone injury) spray for treating soft tissue injury and bone joint injury. The Gushangling spray is mainly prepared from the following bulk drugs in parts by weight: 25-40 parts of peach kernels, 25-40 parts of curcuma longa, 15-30 parts of dragon blood, 80-120 parts of ephedra, 80-120 parts of garden balsam stems, 25-40 parts of Rhizoma Drynariae, 25-40 parts of ground beetles, 30-40 parts of corydalis, 30-40 parts of sappan wood, 30-50 parts of cape jasmine fruits, 30-50 parts of costustoot and 10-30 parts of borneol. The product has the functions of promoting blood circulation and removing blood stasis, clearing and activating the channels and collaterals, promoting qi circulation and relieving pain, and resisting bacterium and diminishing inflammation, can be used for treating soft tissue injuries and bone joint injuries caused by falling, sudden strain, pulling, turning, striking and crushing, and has the significant curative effect on whatever new injury or old injury. The product is a medicine prepared from pure traditional Chinese medicines; moreover, the spray is reasonable in formulas, high in seepage force and high in cure rate, and has no side effects and quick response.
Description
Technical field
The present invention relates to a kind of medicinal herb spray, particularly a kind of can be used for treating flutterring by falling, sprain and contusion, tractive, torsion, clashing into, roll and the bone wound medicine (gushangling) spray of the soft tissue injury that causes and osteoarticular injury disease.
Background technology
Soft tissue injury and osteoarticular injury are sick, and Chang Yin falls and flutters, sprain and contusion, tractive, torsion, clashes into, the External Force Acting such as to roll in human body, and injure meridians and muscles and bones, cause stasis of blood stream, meridians sering is damaged, and local is livid purple swells and ache, joint injury, and muscles and bones is ruptured.Some reverse because work work makes muscle tendon ligament etc. be subject to tractive friction for a long time, can cause the chronic soft tissue injuries of local.Soft tissue injury and osteoarticular injury disease are one of common diseases in people's daily life, and sickness rate is high, has a strong impact on the work of patient, studying and living, all brings great misery to patient and family.For this type of disease, doctor trained in Western medicine adopts for oral administration or external to have the chemical drugs of antiinflammatory, analgesic efficacy, if there is fracture also need additional plaster fixing usually; The traditional Chinese medical science is the Chinese medicine adopting for oral administration or external to have blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, relaxing muscles and tendons and activating QI and blood in the collateral effect then more, and additional clamping plate local is fixing if desired.Because there is untoward reaction and simple antiinflammatory, pain relieving and the defect of joint function recovery can not be promoted to have limited to its use in chemical drugs, Chinese medicine is at antiinflammatory, detumescence, pain relieving and promotion joint function recovery aspect definite effect, but Chinese medicine for oral administration, need through taste, the metabolism of liver, large to injury of human, external application Chinese medicine requires no the metabolism of human body taste liver, medicine can directly act on diseased region to reach the object for the treatment of, rapid-action, but external application Chinese medicine is at prescription, dosage form, curative effect reasonable, feasible, still there is a lot of defect in effective and ease for use aspect, the external application Chinese medicine penetrating power of a lot of conventional dosage forms is weak, skin assimilation effect is poor, also easily cause local skin to stimulate and skin allergy, so need further further investigation badly.
External application Chinese medicine at present about treatment soft tissue injury and osteoarticular injury disease has more patent documentation to report.Such as application number is 02127909.8, name is called " spray agent for treating tendon and bone injury ", which disclose the medicine of a kind of set a broken bone section soft tissue injury disease, main crude drug comprises Herba Polygoni Runcinati, Radix Paeoniae Rubra, Herba Epimedii, Pheretima, Radix Aconiti Kusnezoffii Preparata, Mentholum, this invention product Chinese herbal medicine makes, little to skin damage, detumescence, relieving pain, application number is 201210170987.2, name is called " a kind of swelling-reducing pain-easing ointment and preparation method thereof ", the invention provides and a kind of there is plaster of reducing swelling and alleviating pain effect and preparation method thereof, the method overcome in traditional plaster preparation process and make the shortcoming that in crude drug, active component disappears owing to tempering for a long time, obtained plaster is easy to use, reducing swelling and alleviating pain Be very effective, its Chinese medicine is by Herba Artemisiae Anomalae, Lignum Sappan, Radix Et Rhizoma Rhei, Fructus Gardeniae, Rhizoma Smilacis Glabrae, Olibanum, Myrrha, eupolyphaga, calamitas urinae hominis, Herba speranskiae tuberculatae, Radix Cynanchi Paniculati, Radix Angelicae Pubescentis, Cortex Acanthopancis, the Radix Angelicae Dahuricae, Radix Et Rhizoma Nardostachyos, Rhizoma Chuanxiong, Borneolum Syntheticum and Rhizoma Curcumae Longae 18 taste Chinese medicine are made.With treat the external application Chinese medicine of soft tissue injury with osteoarticular injury disease in prior art and compare, it is reasonable that bone wound medicine (gushangling) spray of the present invention has formula, and formula components is simple, pharmaceutical technology is simple, and cost is low, easy to use, pollution-free, medicinal liquid osmosis power is strong, absorbs rapidly, rapid-action, anti-inflammation, reducing swelling and alleviating pain Be very effective, and can growth of spur be promoted, have effect of reunion of bone concurrently, cure rate is high, has no side effect.
Summary of the invention
The technical problem to be solved in the present invention is problem for treating in currently available technology existing for soft tissue injury and osteoarticular injury disease and defect, a kind of bone wound medicine (gushangling) spray by pure Chinese drug preparation is provided, product pharmaceutical formulation of the present invention is reasonable, and pharmaceutical technology is simple, and cost is low, penetration is strong, absorb rapidly, anti-inflammation, reducing swelling and alleviating pain Be very effective, can promote growth of spur, have effect of reunion of bone concurrently, cure rate is high; And product of the present invention is the pure medicinal herb spray of external type, easy to use, pollution-free, be easy to carry; And medicine requires no the metabolism of human body taste, liver, can direct effect and diseased region, rapid-action, have no side effect.
The technical solution used in the present invention is:
The invention provides a kind of bone wound medicine (gushangling) spray for the treatment of soft tissue injury and osteoarticular injury disease, described bone wound medicine (gushangling) spray makes primarily of the crude drug of following weight portion: 25 ~ 40 parts, Semen Persicae, 25 ~ 40 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 15 ~ 30 parts, 80 ~ 120 parts, Herba Ephedrae, Herba speranskiae tuberculatae 80 ~ 120 parts, Rhizoma Drynariae 25 ~ 40 parts, Eupolyphaga Seu Steleophaga 25 ~ 40 parts, Rhizoma Corydalis 30 ~ 40 parts, Lignum Sappan 30 ~ 40 parts, Fructus Gardeniae 30 ~ 50 parts, the Radix Aucklandiae 30 ~ 50 parts and Borneolum Syntheticum 10 ~ 30 parts.
According to the bone wound medicine (gushangling) spray of above-mentioned treatment soft tissue injury and osteoarticular injury disease, the primary raw material medicine of described bone wound medicine (gushangling) spray is 25.1 ~ 29.9 parts, Semen Persicae, 25.1 ~ 29.9 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 15.1 ~ 19.9 parts, 80.1 ~ 94.9 parts, Herba Ephedrae, Herba speranskiae tuberculatae 80.1 ~ 94.9 parts, Rhizoma Drynariae 25.1 ~ 29.9 parts, Eupolyphaga Seu Steleophaga 25.1 ~ 29.9 parts, Rhizoma Corydalis 30.1 ~ 33 parts, Lignum Sappan 30.1 ~ 33 parts, Fructus Gardeniae 30.1 ~ 37 parts, the Radix Aucklandiae 30.1 ~ 37 parts and Borneolum Syntheticum 10.1 ~ 17 parts.
According to the bone wound medicine (gushangling) spray of above-mentioned treatment soft tissue injury and osteoarticular injury disease, the primary raw material medicine of described bone wound medicine (gushangling) spray is 30.1 ~ 34.9 parts, Semen Persicae, 30.1 ~ 34.9 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 20.1 ~ 24.9 parts, 95.1 ~ 109.9 parts, Herba Ephedrae, Herba speranskiae tuberculatae 95.1 ~ 109.9 parts, Rhizoma Drynariae 30.1 ~ 34.9 parts, Eupolyphaga Seu Steleophaga 30.1 ~ 34.9 parts, Rhizoma Corydalis 33 ~ 36 parts, Lignum Sappan 33 ~ 36 parts, Fructus Gardeniae 37 ~ 43 parts, the Radix Aucklandiae 37 ~ 43 parts and Borneolum Syntheticum 17 ~ 23 parts.
According to the bone wound medicine (gushangling) spray of above-mentioned treatment soft tissue injury and osteoarticular injury disease, the primary raw material medicine of described bone wound medicine (gushangling) spray is 35.1 ~ 40 parts, Semen Persicae, 35.1 ~ 40 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 25.1 ~ 30 parts, 110.1 ~ 120 parts, Herba Ephedrae, Herba speranskiae tuberculatae 110.1 ~ 120 parts, Rhizoma Drynariae 35.1 ~ 40 parts, Eupolyphaga Seu Steleophaga 35.1 ~ 40 parts, Rhizoma Corydalis 36 ~ 40 parts, Lignum Sappan 36 ~ 40 parts, Fructus Gardeniae 43 ~ 50 parts, the Radix Aucklandiae 43 ~ 50 parts and Borneolum Syntheticum 23 ~ 30 parts.
According to the bone wound medicine (gushangling) spray of above-mentioned treatment soft tissue injury and osteoarticular injury disease, the preparation method of described bone wound medicine (gushangling) spray comprises the following steps:
(1) according to the crude drug proportioning of above-mentioned bone wound medicine (gushangling) spray, take various crude drug, various crude drug is put into saucepan, add 2500 ~ 3000ml water, soak 10 ~ 12 hours, be heated to boiling, boil 40 ~ 50 minutes, filter, by medicinal residues elimination, obtain the medicinal liquid 1800 ~ 2200ml boiled; (2) by medicinal liquid 250 mesh screen twice, and then with 300 mesh screen twice, medicinal liquid is collected.
According to the bone wound medicine (gushangling) spray of above-mentioned treatment soft tissue injury and osteoarticular injury disease, the preparation method of described bone wound medicine (gushangling) spray is further comprising the steps of:
After the medicinal liquid cooling of collecting until above-mentioned steps (2), in medicinal liquid weight 1 ‰ ~ 1.5 ‰ ratio add azone, be uniformly mixed.
Using method: general consumption is: once, connecting spray is for four times seance in spray in every three minutes, and carry out four treatments for one day, the person of being in a bad way can increase use amount as one sees fit; Wherein, fracture patient need use after reduction.Note: (swelling pain caused can use this product because fracturing).
Use taboo: skin cut, the person's of festering forbidding.
The pharmacology of various crude drug of the present invention is:
Semen Persicae: sweet-bitter flavor, property is put down, and returns lung, the heart, liver, large intestine four warp.Primary efficacy: blood circulation promoting and blood stasis dispelling, moistening dryness for relaxing bowels, promoting the circulation of blood is dispeled the wind; Can be used for treatment amenorrhea ， WEIJIA, lung abscess, acute appendicitis, traumatic injury, congestion pain, the diseases such as dryness of the intestine constipation.The chemical composition of Semen Persicae has amygdalin, emulsin, volatile oil and fatty wet goods, wherein main containing oleic and a small amount of glyceryl linoleate in oil.
Pharmacological action is: the effect of (1) blood stasis dispelling blood: the water decoction-alcohol sedimentation liquid of Semen Persicae can make isolated rabbit ear vein vascular flow increase, and has vasodilator effect; To anesthetized dog intra-arterial injection, femoral artery blood flow can be increased and reduce vascular resistance, having direct dilating effect to blood vessel wall; And also having suppression blood coagulation and haemolysis, in Semen Persicae extract splenic artery, administration can make blood flow in anesthetized rat liver microcirculation accelerate, and relevant to dosage, points out and has some improvement to liver surface microcirculation; (2) antiinflammatory action: two homogeneous protein ingredients in the protein ingredient of Semen Persicae, intravenous administration, xylol induced mice ear acute inflammatory reaction, all has remarkable inhibitory action; (3) anti-allergic effects: Semen Persicae water extract can suppress the generation of skin-sensitizing antibodies in mice serum and house mouse spleen hemolytic cell; (4) other effect: amygdalin also has antitussive, anthelmintic, bacteriostasis.
Rhizoma Curcumae Longae: acrid in the mouth is bitter, warm in nature, returns liver, spleen two warp.Primary efficacy: removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia, treatment numbness of dispeling the wind, loose three burnt fire stagnation, eliminating carbuncle is loose swollen; Can be used for the treatment thoracic obstruction to love, abdominal distention ， WEIJIA is gathered, traumatic injury, the diseases such as rheumatism shoulder aches.Containing curcumin in the chemical composition of Rhizoma Curcumae Longae, fatty oil and volatilization wet goods, wherein include again turmerone, zingerene, phellandrene, sabinene, Borneolum Syntheticum and deoxidation turmerone etc. in volatile oil.The effects such as modern medicine study confirms that the curcumin in Rhizoma Curcumae Longae has antioxidation, antitumor, blood fat reducing, resists myocardial ischemia, antibacterial, antiinflammatory, antiviral and antifungal.
Rhizoma Curcumae Longae can with Fructus Gardeniae compatibility, Fructus Gardeniae bitter cold, heat-clearing and toxic substances removing, rush down the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels burning hot, enter liver and gall clearing gallbladder jaundice eliminating, Fructus Gardeniae obtains helping of Rhizoma Curcumae Longae circulation of qi promoting blood stasis dispelling, then the power of dredging sharp liver and gall is strengthened, play clearing heat secreting bile altogether, the effect that removing toxic substances relieves the pain, stops up stagnant for liver and gall pyretic toxicity, the heating that blood stasis is depressed, bitter taste, the treatment of the diseases such as the lower pain of the side of body.
Pharmacological action is: (1) choleretic effect: Curcuma and preserved material can increase the bile secretion of dog, makes bile component recover normal; (2) antibacterial, antiinflammatory and analgesic activity: curcumin and volatile oil part have good antibacterial action to staphylococcus aureus, and have significant antiinflammatory action to rat, chmice acute and subacute foot swelling inflammation.Rhizoma Curcumae Longae water logging agent has inhibitory action in various degree to various skin fungus in vitro; Curcuma also has analgesic activity simultaneously; (3) effect for reducing blood fat: curcumol or ether extract, curcumin and volatile oil gavage, have experimental atherosclerosis rats and rabbit and significantly reduce the effect such as serum cholesterol and beta lipoprotein, and can reduce liver cholesterol; (4) anticoagulant and the effect of enhancing fibrinolytic: Rhizoma Curcumae Longae extract and curcumin can increase fibrinolytic, anticoagulant.
Sanguis Draxonis: exhaust also known as black horse Lin, sea wax, dragon's blood, wooden Sanguis Draxonis, sweet in the mouth, salty, property is put down, GUIXIN, liver two warp.Primary efficacy: dissipating blood stasis analgesic therapy, hemostasia and promoting granulation; Can be used for treating traumatic injury, congestion swells and ache, dysmenorrhea, and postpartum stagnation is suffered from abdominal pain, continuous bleeding due to traumatic injury, scrofula, the diseases such as ecthyma unhealed for long time.The main component of Sanguis Draxonis contains resin and volatile oil, also containing vegetalitas dregs, and He Piao phenol etc.Record in " Haiyao Bencao, Oversea Materia Medica " " leadingly traumatic fracture damage, all pain, tonify deficiency and vim and vigour stir thorn, and interior blood trouble is gathered, and should wine clothes "; Record in Tang Materia Medica " main the five internal organs pathogen, leukorrhagia, pain relieving, removing mass blood, gold creation meat "; Record in " detailed outline " " the loose all pains of stagnant blood, married woman's vim and vigour, children's Chi Zong ".
Pharmacological action: (1) antiinflammatory action: experiment shows, Sanguis Draxonis (10%) is to mouse stomach 2g/kg/d, and continuous 7 days, the mice auricle swelling that xylol causes had obvious inhibitory action; Position is scalded in Sanguis Draxonis suspension (20%) coating, and the inflammation at scald position can be made to disappear, and wound obviously reduces, and in incrustation shape, and has the effect promoting wound healing; (2) antibacterial action: the water logging agent (1:2) of Sanguis Draxonis, in vitro to trichophyton, trichophyton gypseum, permitted the dermatophytess such as blue achorion, Du's big belly microspore tinea bacterium difficult to understand, rust microspore tinea bacterium, ulotrichy microspore tinea bacterium, epidermophyton inguinale, epidermophyton rubrum, Candida albicans, star-shaped nocardia and all had inhibitory action in various degree; Also report is had to point out: Sanguis Draxonis has very strong bacteriostasis to staphylococcus aureus, Staphylococcus albus, Staphylococcus citreus, Nai Shi coccus, diphtheria corynebacterium and Bacillus typhi; Stronger bacteriostasis is had to escherichia coli, bacillus pyocyaneus, shigella flexneri etc.; (3) on hemorheological property and the impact on platelet aggregation: Sanguis Draxonis can make blood flow unobstructed, prevent thrombosis, obviously can reduce erythrocyte hematocrit, accelerate the electrophoretic velocity of erythrocyte in DC electric field, suppress hematoblastic gathering and accelerate hematoblastic electrophoretic velocity.
Herba Ephedrae: acrid in the mouth, micro-hardship, warm in nature, return lung, large intestine, pericardium, bladder four warp.Primary efficacy: relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, inducing diuresis to remove edema, expelling cold and freeing bi; Can be used for treating anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema, the diseases such as bronchial asthma.
Pharmacological action: (1) stimulating central nervous system effect: Herba Ephedrae all has excitation to brain, breathing and circulation maincenter; (2) anti-allergic effects: the water extract of Herba Ephedrae has anti-allergic effects, can suppress the release of sensitizer, local action, nasal mucosa vessels can be made to shrink, therefore can treat rhinitis; (3) antiinflammatory action: Herba Ephedrae extract has antiinflammatory action to Experimental Inflammation, the multiple alkaloid in its chemical composition has inhibitory action to toes inflammatory edema; (4) analgesic activity: the ephedrine in Herba Ephedrae extract has central analgesic activity; (5) antibacterial, antivirus action: the water decoction of Herba Ephedrae and Herba Ephedrae volatile oil have antibacterial action in various degree to various bacteria, have inhibitory action to Asia influenza A virus, has therapeutical effect to mouse infection influenza A virus PR8 strain.
Herba speranskiae tuberculatae: sweet in the mouth is pungent, warm in nature, return lung, liver two warp.Primary efficacy: expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation and stopping pain, solution poisons rash; Can be used for treating rheumatic arthralgia, muscles and bones contracture, the disturbance of lower legs due to pathogenic cold and dampness, the diseases such as skin ulcer tinea toxic swelling.
Pharmacological action: (1) analgesia, anti rheumatism action: the water decoction of Herba speranskiae tuberculatae has analgesia, anti rheumatism action, similar to Salicylates; (2) antiinflammatory, sterilization, the effect of convergence wound surface: the external of Herba speranskiae tuberculatae water decoction has antiinflammatory, sterilization, the effect of convergence wound surface, is suitable for general skin ulcer tinea toxic swelling.
Rhizoma Drynariae: bitter in the mouth, warm in nature, return liver, kidney two warp.Primary efficacy: the kidney invigorating bone strengthening, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, continues and hinders pain relieving, reunion of fractured tendons and bones; Can be used for treatment to suffer from a deficiency of the kidney pain in the lumbar region, Hiccough and deaf, toothache, chronic diarrhea, the diseases such as poor vision, be usually used in clinically treating traumatic injury, pain caused by ecchymoma, fracture is traumatology key medicine.
Pharmacological action: (1) osteomiosis complementary energy promotes that bone is to the absorption of calcium, and improves the level of blood calcium and serium inorganic phosphorus, thus is conducive to the healing of fracture; (2) Rhizoma Drynariae has some improvement the function of chondrocyte, has the effect postponing cell regeneration pathological changes; (3) naringenin in Rhizoma Drynariae chemical composition has significantly analgesia and sedation.
Eupolyphaga Seu Steleophaga: also known as eupolyphaga, salty in the mouth, cold in nature, return liver, kidney two warp.Primary efficacy: removing blood stasis, inducing menstruation to relieve menalgia, detumescence is cured the wound, reunion of fractured tendons and bones, kidney tonifying bone strengthening; Can be used for treatment blood stasis amenorrhea ， WEIJIA to gather, puerperal abdonimal pain, the diseases such as traumatic injury; Especially to traumatic injury, the stasis of blood is stagnant to swell and ache, and the fracture pain of injury has obvious curative effects." control injury from falling down, reuniting the fractured tendons and bones has special effect " is recorded in " Bencao Jingshu "; In " hospital's summary ", record is singly got this product and is roasted last taking orally, " can control injured, synthetism "; Record in " explaining abstruseness of the canon of materia medica " " all accumulation of blood broken, traumatic injury severe injury, synthetism ".
Pharmacological action: have inhibitory action to leukaemia.
Rhizoma Corydalis: also known as Rhizoma Corydalis, acrid in the mouth is bitter, warm in nature, GUIXIN, liver, spleen three warp.Primary efficacy: promoting blood circulation to remove blood stasis, promoting the circulation of QI to relieve pain; Can be used for all pains for the treatment of trusted subordinate's waist knee joint, qi depression to blood stasis, dysmenorrhea, amenorrhea, lump in the abdomen, the diseases such as traumatic injury.Record in Compendium of Material Medica " stagnation of QI in the promoting the circulation of blood of Rhizoma Corydalis energy, stasis in gas, therefore cure mainly upper and lower all pains all over the body, with among, simply fantastic.”
Pharmacological action: (1) analgesic activity: the alkaloid in Rhizoma Corydalis chemical composition has analgesic activity; (2) sedative-hypnotic effect: after experiment proves to gavage Rhizoma Corydalis B prime to monkey, visible movable minimizing, drowsiness of bowing, aggressive reaction disappears; (3) on the impact of cardio-cerebrovascular: the observation of the full alkali of use for laboratory Rhizoma Corydalis to guinea pig ECG shows, energy is decreased heart rate significantly, and has antagonism to the ECG change that pituitrin causes, and arrhythmia is disappeared; (4) to gastrointestinal tract effect: experiment proves, this product can suppress gastric secretion in a large number, and has antiulcer action.
Lignum Sappan: sweet-salty, property is put down, and returns liver, stomach, large intestine three warp.Primary efficacy: promoting the circulation of blood removing blood stasis with potent drugs, reducing swelling and alleviating pain; Can be used for treating amenorrhea due to stagnation of blood, dysmenorrhea, prolonged lochia, skin sore, traumatic injury, the disease such as dysentery and tetanus.Lignum Sappan can with Semen Persicae compatibility, two medicines all have promoting blood circulation to restore menstrual flow, effect of eliminating blood stasis to promote regeneration of blood, and the two mutual reinforcement between is use, can promoting blood circulation to disperse blood clots and relieves pain, treatment women amenorrhea, abdominal pain due to blood stasis and various swelling and pain due to blood stasis etc.
Pharmacological action: (1) is to Central nervous depressant: appropriate Lignum Sappan water, with Various medications, all have syngignoscism to mice, rabbit, Cavia porcellus, a large amount of use still has anesthetic action; (2) antibacterial action: Lignum Sappan decoct has stronger antibacterial action to staphylococcus aureus, Bacillus typhi, diphtheria corynebacterium, hemophilus influenza, Hemolytic streptococcus and streptococcus pneumoniae etc.
Fructus Gardeniae: bitter in the mouth, cold in nature, GUIXIN, liver, lung, stomach, kidney, bladder the six channels.Primary efficacy: clearing the stagnated heat, purge heat dampness removing, cooling blood for hemostasis, reducing swelling and alleviating pain, heat-clearing and toxic substances removing; May be used for treatment calentura restlessness of asrhenia type and insomnia, jaundice, aphtha halitosis, pyretic stranguria, stranguria with blood, conjunctival congestion and swelling pain, pathopyretic ulcer, sprains and swells and ache, the diseases such as tendon injury.
Pharmacological action: (1) choleretic effect: zoopery proves, Fructus Gardeniae aqueous extract and alcohol extractum all have choleretic effect, wherein stronger with aqueous extract choleretic effect; (2) sedation: white mice subcutaneous injection Fructus Gardeniae fluid extract, makes spontaneous activity reduce, close order, bow, of flaccid muscles, and the convulsions that the anti-pentetrazole of energy causes; (3) hypotensive effect: zoopery proves, Fructus Gardeniae decoct and alcohol extract, to anesthesia or the cat of not anaesthetizing, rat and rabbit, no matter oral or intraperitoneal injection, all have persistency hypotensive effect; (4) antibacterial action: experiment in vitro proves, Fructus Gardeniae infusion has inhibitory action to various bacteria such as dysentery bacterium, staphylococcus aureus, bacillus pyocyaneus; In vitro, Fructus Gardeniae water decoction has inhibitory action to multiple funguses such as many achorions, epidermophyton inguinale, epidermophyton rubrums; (5) refrigeration function: Fructus Gardeniae decoct can suppress heating maincenter, so there is antipyretic effect; (6) anastalsis: Fructus Gardeniae, Fructus Gardeniae Preparatus, classed FRUCTUS GARDENIAE all have anastalsis, and the anastalsis of Fructus Gardeniae is stronger; (8) healing of soft tissue injury is accelerated: the unguentum that Fructus Gardeniae extract is made can accelerate the healing of soft tissue contusion.
The Radix Aucklandiae: acrid in the mouth is bitter, warm in nature, returns lung, liver, spleen, stomach four warp.Primary efficacy: promoting the circulation of QI to relieve pain, warming middle-JIAO for easing the stomach, inducing diuresis for treating stranguria syndrome, wards off poison and to disappear evil, the Piization that disappears wei; Can be used for treatment gastral cavity abdomen to swell and ache, hypochondriac pain due to stagnation of liverQI, damp-heat dysentery, colic of cold type pain, food stagnation does not disappear, vomiting, the diseases such as diarrhea due to cold pathogen.
Pharmacological action: (1) antibacterial action: Radix Aucklandiae water decoction has inhibitory action to Salmonella paratyphi first in test tube, also has inhibitory action to some pathomycete; (2) spasmolysis: the spasm of the alkaloid in Radix Aucklandiae chemical composition to the guinea pig bronchial intestinal smooth muscle that histamine causes has obvious spasmolysis.
Borneolum Syntheticum: acrid in the mouth is bitter, cool in nature, GUIXIN, lung two warp.Primary efficacy: refreshment of having one's ideas straightened out, clearing away heat to alleviate pain life; May be used for treatment apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, open and close deaf, aphtha, laryngopharynx swelling and pain, carbuncle, the diseases such as conjunctival congestion.
Pharmacological action: (1) pain relieving and anticorrosion: Borneolum Syntheticum is used for local, and it is very little to the zest of sensory nerve ending, experiment proves that this product has the antisepsis of some pain relieving and gentleness; (2) antibacterial action: bacteriostatic experiment proves, this product can suppress the growth of hog cholera vibrio, escherichia coli and staphylococcus aureus in vitro.
Camphora: acrid in the mouth, hot in nature, GUIXIN, spleen two warp.Primary efficacy: sensible, pain relieving, dehumidifying parasite killing, eliminating stasis to stop pain; Can be used for treatment trusted subordinate distending pain, beriberi, skin infection scabies, toothache, the diseases such as traumatic injury." orifice opening, qi stagnation removing, control pathogen, cholera, cardiac and abdominal pain, the disturbance of lower legs due to pathogenic cold and dampness, scabies, parasite killing, in footwear and go beriberi " is recorded in Compendium of Material Medica; Record in " Prescriptions for Universal Relief " " do cream control to put malignant boil and beat flutter damage, the diseases such as rheumatism beriberi ".
Pharmacological action: (1) local action: Camphora is applied to skin gentle stimulation and antisepsis, firmly embrocated and sent out red effect, dab is similar Herba Menthae then, has refrigerant sense, and has pain relieving, antipruritic and locally slight anesthetic action; (2) to the effect of central nervous system: Camphora energy stimulating central nervous system system, promote and breathe and circulation, when central nervous system is in inhibitory state, excitation is particularly evident; (3) to the effect of gastric mucosa: taking Camphora, that stomach can be made to bask is comfortable.
Azone: a kind of oily liquids of colourless or yellowish clarification is a kind of pharmaceutic adjuvant.Purposes: can be used as penetrating agent, for cream frost all kinds of in cosmetics and hair care product; The penetrating agent of smear as external used medicine, massaging; For medical aspect, transdermal helps infiltration, can increase drug effect, thus can be cost-saving; For pesticide, as the penetrating agent of the short vapor of plant growth regulator and sterilization, insecticide; In addition, also can be used for the painted promoter in the field such as leather and printing and dyeing.
Pharmacological action: as dermal osmosis accelerator, can change skin chromaticness layer lipid and protein structure, promotes that drug percutaneous skin absorbs, can strengthen its transdermal effect to hydrophilic and hydrophobic compound; To skin, mucosa nonirritant, in ointment, cream, liniment, add this product all can play Transdermal absorption effect; Can be used as the adjuvant of the medicine for external use such as ointment, cream, liniment.
Positive beneficial effect of the present invention:
In the crude drug of 1, product of the present invention with Herba Ephedrae and Herba speranskiae tuberculatae for monarch drug, with Semen Persicae, Rhizoma Curcumae Longae and Eupolyphaga Seu Steleophaga for ministerial drug, Rhizoma Corydalis, Lignum Sappan and Fructus Gardeniae are adjuvant drug, and Sanguis Draxonis, Rhizoma Drynariae, the Radix Aucklandiae, Borneolum Syntheticum and Camphora are for making medicine, monarch assembly is reasonable, can blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, dredge the meridian passage, reducing swelling and alleviating pain, promote growth of spur, have effect of reunion of fractured tendons and bones concurrently, reach the object of curing the swelling pain disease caused by soft tissue injury and osteoarticular injury.
2, product pharmaceutical technology of the present invention is simple, and cost is low, and medicinal liquid osmosis power is strong, absorbs rapidly, rapid-action, anti-inflammation, reducing swelling and alleviating pain Be very effective, and cure rate is high; And for open fracture and comminuted fracture disease, after the process such as wrapping or Boards wall, due to the local swelling pain that this type of fracture disease causes, use product of the present invention to have significant reducing swelling and alleviating pain effect.
3, product of the present invention is the pure medicinal herb spray of external type, easy to use, pollution-free, is easy to carry; And medicine requires no the metabolism of human body taste, liver, can direct effect and diseased region, rapid-action, have no side effect.
4, therapeutic effect:
(1) efficacy assessment standard:
Cure: for soft tissue injury disease, swelling pain symptom is eliminated completely, and affected site functional rehabilitation is normal; Cause swelling pain disease for fracture, swelling pain symptom is eliminated completely;
Effective: for soft tissue injury disease, local swelling pain symptom has and obviously alleviates, and affected site function has obvious recovery; Cause swelling pain disease for fracture, swelling pain symptom has and obviously alleviates;
Invalid: swelling pain sings and symptoms is without being clearly better.
The bone wound medicine (gushangling) spray that the present invention treats soft tissue injury and osteoarticular injury treated 146 cases altogether from 2008 ~ 2013, wherein had 53 examples by the patient of the swelling pain disease caused of fracturing, and comprised male patient 39 example, female patient 14 example; Soft tissue injury patient has 95 examples, comprises male patient 50 example, female patient 45 example.Minimal ages 22 years old in the middle of all patients, max age 80 years old, 51 years old mean age.
Through statistics, fully recover in 146 routine patients 139 people, accounts for 95.21%; Effective 7 examples, account for 100%; None example is invalid.
5, model case:
(1) grandson, man, 45 years old, Shi Fo people from town, high and new technology industrial development zone, Zhengzhou City Henan Province, because in the middle of work, left index finger, by machine pusher, causes fracture, hospitalization one month, forefinger always swelling pain is severe, does not feel any better, and carrys out this clinics after being introduced, examine and see that forefinger is livid purple, swelling, pain with tenderness, and can not bend; Use bone wound medicine (gushangling) spray, livid purple after five days, swelling has obviously disappears, and to use after ten days forefinger can flexion, uses three weeks afterwards swelling pain symptom disappear completely, healing, follows up a case by regular visits to 2 years without malaise symptoms.
(2) Lee, man, 56 years old, Tang Li people from village, high and new technology industrial development zone, Zhengzhou City Henan Province, because waist is pulled at work, in town, hospitalize first quarter moon is had a surplus, and does not feel any better, and carrys out this clinic upon somebody's introduction, examine and see that turn-over bed for patient works difficulty of being confined, walking needs people to assist in, and waist fourth, fifth saves that vertebra is right outside opens 5 centimetres by being pressed with obvious pain, use bone wound medicine (gushangling) spray after four days pain obviously alleviate, use and can to walk after ten days and not employment is assisted in, after using first quarter moon, swelling pain symptom disappears completely, cures, and follows up a case by regular visits to 2 years health as former times.
(3) Wang, man, 25 years old, Gu Xing town, Huiji District, Zhengzhou City Henan Province Ji Gongmiao people from village, spraining one's ankle because of carelessness during because playing ball, carrying out this clinics, examine and see that there is green grass or young crops of significantly becoming silted up at ankle place, swelling is severe, and pain is unable, use bone wound medicine (gushangling) spray, three days afterwards silt green grass or young crops disappear, distending pain sense obviously alleviates, and uses swelling pain symptom after the Ninth Heaven to disappear completely, cure, follow up a case by regular visits to 2 years without malaise symptoms.
(4) certain is paid, female, 63 years old, Nanyang people from stockaded village of JinShui, Zhengzhou City, Henan Province district, causes wrist to sprain because falling down, and sprains in later six months through multi-treatment, do not feel any better, patient is wrist swelling pain often over the past half year, and hand is unable, aggravation after tired, carrys out this clinics upon somebody's introduction, uses bone wound medicine (gushangling) spray, after one week, swelling pain sense alleviates, after three weeks, swelling pain symptom disappears completely, cures, and follows up a case by regular visits to not recurrence in 3 years.
(5) Zhang, man, 57 years old, Ji Gongmiao people from village, Huiji District, Zhengzhou City Henan Province, because falling down by motorcycle, causes fracture of lower leg, hospitalization is after one month, although fracture site has taked wrapping and Boards wall treatment, whole piece lower limb swelling pain severity, with this clinics afterwards, examine and see that shank swelling is become silted up obviously blue or green, pain with tenderness, not movable, use bone wound medicine (gushangling) spray, swelling after one week, silt green grass or young crops obviously alleviate, after using three weeks, swelling pain symptom disappears completely, cures, follows up a case by regular visits to 2 years without malaise symptoms.
(6) literary composition certain, man, 54 years old, Ji Gongmiao people from village, Huiji District, Zhengzhou City Henan Province, because traumatic injury causes fracture of lower leg, undergoes various treatments over one year, but patient's shank swelling pain always, unable, carry out this clinics after being introduced, examine and see shank swelling, use bone wound medicine (gushangling) spray, after five days, swelling pain has and obviously alleviates, uses three weeks afterwards swelling pain symptom disappear completely, cure, follow up a case by regular visits to 2 years without malaise symptoms.
(7) in 4.20 Yaan earthquakes in 2013, the present inventor carries 20 jin of products of the present invention---and bone wound medicine (gushangling) spray hurries to disaster area, participate in the masses suffering from disaster for the treatment of soft tissue injury and osteoarticular injury, all achieve remarkable result, wherein Shao, man, 42 years old, Chengdu, Sichuan Province Xiaojin County Military Affairs Office officers and men, the horizontal slotting shank of reinforcing bar is met with in earthquake relief work process, although wound is through wrapping process, but the heating of whole piece lower limb swelling pain is severe, stiffly cannot to bend, night, pain cannot be fallen asleep, use bone wound medicine (gushangling) spray after three days patient's pain obviously alleviate, can to fall asleep rest, use swelling pain after six days to have obviously to disappear, after using two weeks, patient's leg swelling pain symptom is eliminated completely.
concrete embodiment:
Set forth the present invention further below in conjunction with embodiment, but do not limit content of the present invention.
Embodiment 1:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 25 parts, Semen Persicae, 25 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 15 parts, 80 parts, Herba Ephedrae, Herba speranskiae tuberculatae 80 parts, Rhizoma Drynariae 25 parts, Eupolyphaga Seu Steleophaga 25 parts, Rhizoma Corydalis 30 parts, Lignum Sappan 30 parts, Fructus Gardeniae 30 parts, the Radix Aucklandiae 30 parts and Borneolum Syntheticum 10 parts.
According to the crude drug proportioning of above-mentioned bone wound medicine (gushangling) spray, take various crude drug, various crude drug is put into saucepan, add 2500 ~ 3000ml water, soak 10 ~ 12 hours, be heated to boiling, boil 40 ~ 50 minutes, filter, by medicinal residues elimination, obtain the medicinal liquid 1800 ~ 2200ml boiled; By medicinal liquid 250 mesh screen twice, and then with 300 mesh screen twice, collect medicinal liquid.
Embodiment 2:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 25.1 parts, Semen Persicae, 25.1 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 15.1 parts, 80.1 parts, Herba Ephedrae, Herba speranskiae tuberculatae 80.1 parts, Rhizoma Drynariae 25.1 parts, Eupolyphaga Seu Steleophaga 25.1 parts, Rhizoma Corydalis 30.1 parts, Lignum Sappan 30.1 parts, Fructus Gardeniae 30.1 parts, the Radix Aucklandiae 30.1 parts, Borneolum Syntheticum 10.1 parts and Camphora 10.
Preparation method is identical with embodiment 1.
Embodiment 3:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 27 parts, Semen Persicae, 27 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 17 parts, 85 parts, Herba Ephedrae, Herba speranskiae tuberculatae 85 parts, Rhizoma Drynariae 27 parts, Eupolyphaga Seu Steleophaga 27 parts, Rhizoma Corydalis 32 parts, Lignum Sappan 32 parts, Fructus Gardeniae 33 parts, the Radix Aucklandiae 33 parts, Borneolum Syntheticum 13 parts and Camphora 12.
Preparation method is identical with embodiment 1.
Embodiment 4:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 29.9 parts, Semen Persicae, 29.9 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 19.9 parts, 90 parts, Herba Ephedrae, Herba speranskiae tuberculatae 90 parts, Rhizoma Drynariae 29.9 parts, Eupolyphaga Seu Steleophaga 29.9 parts, Rhizoma Corydalis 33 parts, Lignum Sappan 33 parts, Fructus Gardeniae 35 parts, the Radix Aucklandiae 35 parts and Borneolum Syntheticum 15 parts.
According to the crude drug proportioning of above-mentioned bone wound medicine (gushangling) spray, take various crude drug, various crude drug is put into saucepan, add 2500 ~ 3000ml water, soak 10 ~ 12 hours, be heated to boiling, boil 40 ~ 50 minutes, filter, by medicinal residues elimination, obtain the medicinal liquid 1800 ~ 2200ml boiled; By medicinal liquid 250 mesh screen twice, and then with 300 mesh screen twice, collect medicinal liquid; Until medicinal liquid cooling after, in medicinal liquid weight 1 ‰ ~ 1.5 ‰ ratio add azone, be uniformly mixed.
Embodiment 5:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 30 parts, Semen Persicae, 30 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 20 parts, 94.9 parts, Herba Ephedrae, Herba speranskiae tuberculatae 94.9 parts, Rhizoma Drynariae 30 parts, Eupolyphaga Seu Steleophaga 30 parts, Rhizoma Corydalis 35 parts, Lignum Sappan 35 parts, Fructus Gardeniae 34.9 parts, the Radix Aucklandiae 34.9 parts and Borneolum Syntheticum 14.9 parts.
Preparation method is identical with embodiment 4.
Embodiment 6:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 30.1 parts, Semen Persicae, 30.1 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 20.1 parts, 95 parts, Herba Ephedrae, Herba speranskiae tuberculatae 95 parts, Rhizoma Drynariae 30.1 parts, Eupolyphaga Seu Steleophaga 30.1 parts, Rhizoma Corydalis 35.1 parts, Lignum Sappan 35.1 parts, Fructus Gardeniae 35.1 parts, the Radix Aucklandiae 35.1 parts, Borneolum Syntheticum 15.1 parts and Camphora 11.
Preparation method is identical with embodiment 1.
Embodiment 7:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 32 parts, Semen Persicae, 32 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 22 parts, 95.1 parts, Herba Ephedrae, Herba speranskiae tuberculatae 95.1 parts, Rhizoma Drynariae 32 parts, Eupolyphaga Seu Steleophaga 32 parts, Rhizoma Corydalis 36 parts, Lignum Sappan 36 parts, Fructus Gardeniae 37 parts, the Radix Aucklandiae 37 parts and Borneolum Syntheticum 17 parts.
Preparation method is identical with embodiment 4.
Embodiment 8:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 34.9 parts, Semen Persicae, 34.9 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 24.9 parts, 100 parts, Herba Ephedrae, Herba speranskiae tuberculatae 100 parts, Rhizoma Drynariae 34.9 parts, Eupolyphaga Seu Steleophaga 34.9 parts, Rhizoma Corydalis 38 parts, Lignum Sappan 38 parts, Fructus Gardeniae 39.9 parts, the Radix Aucklandiae 39.9 parts, Borneolum Syntheticum 19.9 parts and Camphora 18.
Preparation method is identical with embodiment 1.
Embodiment 9:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 35 parts, Semen Persicae, 35 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 25 parts, 105 parts, Herba Ephedrae, Herba speranskiae tuberculatae 105 parts, Rhizoma Drynariae 35 parts, Eupolyphaga Seu Steleophaga 35 parts, Rhizoma Corydalis 39.9 parts, Lignum Sappan 39.9 parts, Fructus Gardeniae 40 parts, the Radix Aucklandiae 40 parts and Borneolum Syntheticum 20 parts.
Preparation method is identical with embodiment 1.
Embodiment 10:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 35.1 parts, Semen Persicae, 35.1 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 25.1 parts, 109.9 parts, Herba Ephedrae, Herba speranskiae tuberculatae 109.9 parts, Rhizoma Drynariae 35.1 parts, Eupolyphaga Seu Steleophaga 35.1 parts, Rhizoma Corydalis 40 parts, Lignum Sappan 40 parts, Fructus Gardeniae 43 parts, the Radix Aucklandiae 43 parts, Borneolum Syntheticum 22 parts and Camphora 20.
Preparation method is identical with embodiment 4.
Embodiment 11:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 37 parts, Semen Persicae, 37 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 28 parts, 110 parts, Herba Ephedrae, Herba speranskiae tuberculatae 110 parts, Rhizoma Drynariae 37 parts, Eupolyphaga Seu Steleophaga 37 parts, Rhizoma Corydalis 31 parts, Lignum Sappan 31 parts, Fructus Gardeniae 45 parts, the Radix Aucklandiae 45 parts and Borneolum Syntheticum 25 parts.
Preparation method is identical with embodiment 4
Embodiment 12:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 39.9 parts, Semen Persicae, 39.9 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 29.9 parts, 110.1 parts, Herba Ephedrae, Herba speranskiae tuberculatae 110.1 parts, Rhizoma Drynariae 39.9 parts, Eupolyphaga Seu Steleophaga 39.9 parts, Rhizoma Corydalis 34 parts, Lignum Sappan 34 parts, Fructus Gardeniae 48 parts, the Radix Aucklandiae 48 parts and Borneolum Syntheticum 27 parts.
Preparation method is identical with embodiment 1
Embodiment 13:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 40 parts, Semen Persicae, 40 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 30 parts, 115 parts, Herba Ephedrae, Herba speranskiae tuberculatae 115 parts, Rhizoma Drynariae 40 parts, Eupolyphaga Seu Steleophaga 40 parts, Rhizoma Corydalis 31 parts, Lignum Sappan 31 parts, Fructus Gardeniae 49.9 parts, the Radix Aucklandiae 49.9 parts, Borneolum Syntheticum 29.9 parts and Camphora 11.
Preparation method is identical with embodiment 4.
Embodiment 14:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 28 parts, Semen Persicae, 26 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 18 parts, 119.9 parts, Herba Ephedrae, Herba speranskiae tuberculatae 119.9 parts, Rhizoma Drynariae 28 parts, Eupolyphaga Seu Steleophaga 30 parts, Rhizoma Corydalis 37 parts, Lignum Sappan 35 parts, Fructus Gardeniae 50 parts, the Radix Aucklandiae 50 parts, Borneolum Syntheticum 30 parts and Camphora 14.
Preparation method is identical with embodiment 4.
Embodiment 15:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 26 parts, Semen Persicae, 28 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 20 parts, 120 parts, Herba Ephedrae, Herba speranskiae tuberculatae 120 parts, Rhizoma Drynariae 28 parts, Eupolyphaga Seu Steleophaga 36 parts, Rhizoma Corydalis 32 parts, Lignum Sappan 34 parts, Fructus Gardeniae 32 parts, the Radix Aucklandiae 38 parts and Borneolum Syntheticum 18 parts.
Preparation method is identical with embodiment 1.
Embodiment 16:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 27 parts, Semen Persicae, 35 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 25 parts, 83 parts, Herba Ephedrae, Herba speranskiae tuberculatae 83 parts, Rhizoma Drynariae 26 parts, Eupolyphaga Seu Steleophaga 32 parts, Rhizoma Corydalis 39 parts, Lignum Sappan 35 parts, Fructus Gardeniae 36 parts, the Radix Aucklandiae 34 parts, Borneolum Syntheticum 20 parts and Camphora 13.
Preparation method is identical with embodiment 1.
Embodiment 17:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 30 parts, Semen Persicae, 30 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 30 parts, 88 parts, Herba Ephedrae, Herba speranskiae tuberculatae 88 parts, Rhizoma Drynariae 5 parts, Eupolyphaga Seu Steleophaga 40 parts, Rhizoma Corydalis 38 parts, Lignum Sappan 30 parts, Fructus Gardeniae 40 parts, the Radix Aucklandiae 45 parts, Borneolum Syntheticum 24 parts and Camphora 14.
Preparation method is identical with embodiment 1.
Embodiment 18:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 35 parts, Semen Persicae, 30 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 18 parts, 92 parts, Herba Ephedrae, Herba speranskiae tuberculatae 92 parts, Rhizoma Drynariae 28 parts, Eupolyphaga Seu Steleophaga 35 parts, Rhizoma Corydalis 32 parts, Lignum Sappan 36 parts, Fructus Gardeniae 42 parts, the Radix Aucklandiae 46 parts and Borneolum Syntheticum 26 parts.
Preparation method is identical with embodiment 4.
Embodiment 19:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 34 parts, Semen Persicae, 31 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 22 parts, 98 parts, Herba Ephedrae, Herba speranskiae tuberculatae 98 parts, Rhizoma Drynariae 36 parts, Eupolyphaga Seu Steleophaga 36 parts, Rhizoma Corydalis 34 parts, Lignum Sappan 30 parts, Fructus Gardeniae 44 parts, the Radix Aucklandiae 42 parts and Borneolum Syntheticum 28 parts.
Preparation method is identical with embodiment 4.
Embodiment 20:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 28 parts, Semen Persicae, 36 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 26 parts, 100 parts, Herba Ephedrae, Herba speranskiae tuberculatae 100 parts, Rhizoma Drynariae 32 parts, Eupolyphaga Seu Steleophaga 28 parts, Rhizoma Corydalis 33 parts, Lignum Sappan 31 parts, Fructus Gardeniae 46 parts, the Radix Aucklandiae 49 parts, Borneolum Syntheticum 12 parts and Camphora 16.
Preparation method is identical with embodiment 1.
Embodiment 21:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 38 parts, Semen Persicae, 32 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 26 parts, 104 parts, Herba Ephedrae, Herba speranskiae tuberculatae 102 parts, Rhizoma Drynariae 36 parts, Eupolyphaga Seu Steleophaga 33 parts, Rhizoma Corydalis 30 parts, Lignum Sappan 35 parts, Fructus Gardeniae 47 parts, the Radix Aucklandiae 50 parts, Borneolum Syntheticum 21 parts and Camphora 19.
Preparation method is identical with embodiment 1.
Embodiment 22:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 26 parts, Semen Persicae, 26 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 28 parts, 105 parts, Herba Ephedrae, Herba speranskiae tuberculatae 105 parts, Rhizoma Drynariae 30 parts, Eupolyphaga Seu Steleophaga 35 parts, Rhizoma Corydalis 38 parts, Lignum Sappan 34 parts, Fructus Gardeniae 50 parts, the Radix Aucklandiae 45 parts and Borneolum Syntheticum 26 parts.
Preparation method is identical with embodiment 4.
Embodiment 23:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 36 parts, Semen Persicae, 30 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 26 parts, 108 parts, Herba Ephedrae, Herba speranskiae tuberculatae 108 parts, Rhizoma Drynariae 29 parts, Eupolyphaga Seu Steleophaga 29 parts, Rhizoma Corydalis 32 parts, Lignum Sappan 35 parts, Fructus Gardeniae 42 parts, the Radix Aucklandiae 45 parts and Borneolum Syntheticum 29 parts.
Preparation method is identical with embodiment 4.
Embodiment 24:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 25 parts, Semen Persicae, 32 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 30 parts, 110 parts, Herba Ephedrae, Herba speranskiae tuberculatae 110 parts, Rhizoma Drynariae 28 parts, Eupolyphaga Seu Steleophaga 30 parts, Rhizoma Corydalis 30 parts, Lignum Sappan 36 parts, Fructus Gardeniae 35 parts, the Radix Aucklandiae 38 parts, Borneolum Syntheticum 30 parts and Camphora 19.
Preparation method is identical with embodiment 1.
Embodiment 25:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 25 parts, Semen Persicae, 25 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 15 parts, 114 parts, Herba Ephedrae, Herba speranskiae tuberculatae 112 parts, Rhizoma Drynariae 34 parts, Eupolyphaga Seu Steleophaga 37 parts, Rhizoma Corydalis 36 parts, Lignum Sappan 32 parts, Fructus Gardeniae 36 parts, the Radix Aucklandiae 32 parts, Borneolum Syntheticum 18 parts and Camphora 20.
Preparation method is identical with embodiment 4.
Embodiment 26:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 35 parts, Semen Persicae, 30 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 18 parts, 118 parts, Herba Ephedrae, Herba speranskiae tuberculatae 118 parts, Rhizoma Drynariae 40 parts, Eupolyphaga Seu Steleophaga 40 parts, Rhizoma Corydalis 37 parts, Lignum Sappan 35 parts, Fructus Gardeniae 46 parts, the Radix Aucklandiae 48 parts and Borneolum Syntheticum 26 parts.
Preparation method is identical with embodiment 4.
Embodiment 27:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 31 parts, Semen Persicae, 34 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 25 parts, 120 parts, Herba Ephedrae, Herba speranskiae tuberculatae 120 parts, Rhizoma Drynariae 26 parts, Eupolyphaga Seu Steleophaga 32 parts, Rhizoma Corydalis 37 parts, Lignum Sappan 35 parts, Fructus Gardeniae 35 parts, the Radix Aucklandiae 35 parts and Borneolum Syntheticum 20 parts.
Preparation method is identical with embodiment 1.
Embodiment 28:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 35 parts, Semen Persicae, 34 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 28 parts, 80 parts, Herba Ephedrae, Herba speranskiae tuberculatae 85 parts, Rhizoma Drynariae 28 parts, Eupolyphaga Seu Steleophaga 28 parts, Rhizoma Corydalis 31 parts, Lignum Sappan 31 parts, Fructus Gardeniae 44 parts, the Radix Aucklandiae 44 parts, Borneolum Syntheticum 16 parts and Camphora 15.
Preparation method is identical with embodiment 4.
Embodiment 29:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 36 parts, Semen Persicae, 30 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 26 parts, 85 parts, Herba Ephedrae, Herba speranskiae tuberculatae 86 parts, Rhizoma Drynariae 28 parts, Eupolyphaga Seu Steleophaga 34 parts, Rhizoma Corydalis 33 parts, Lignum Sappan 34 parts, Fructus Gardeniae 32 parts, the Radix Aucklandiae 30 parts, Borneolum Syntheticum 21 parts and Camphora 17.
Preparation method is identical with embodiment 4.
Embodiment 30:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 28 parts, Semen Persicae, 28 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 28 parts, 90 parts, Herba Ephedrae, Herba speranskiae tuberculatae 85 parts, Rhizoma Drynariae 26 parts, Eupolyphaga Seu Steleophaga 26 parts, Rhizoma Corydalis 36 parts, Lignum Sappan 36 parts, Fructus Gardeniae 35 parts, the Radix Aucklandiae 35 parts and Borneolum Syntheticum 20 parts.
Preparation method is identical with embodiment 4.
Embodiment 31:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 30 parts, Semen Persicae, 28 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 30 parts, 82 parts, Herba Ephedrae, Herba speranskiae tuberculatae 95 parts, Rhizoma Drynariae 33 parts, Eupolyphaga Seu Steleophaga 37 parts, Rhizoma Corydalis 32 parts, Lignum Sappan 39 parts, Fructus Gardeniae 47 parts, the Radix Aucklandiae 39 parts and Borneolum Syntheticum 19 parts.
Preparation method is identical with embodiment 1.
Embodiment 32:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 27 parts, Semen Persicae, 33 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 26 parts, 95 parts, Herba Ephedrae, Herba speranskiae tuberculatae 88 parts, Rhizoma Drynariae 27 parts, Eupolyphaga Seu Steleophaga 33 parts, Rhizoma Corydalis 37 parts, Lignum Sappan 32 parts, Fructus Gardeniae 36 parts, the Radix Aucklandiae 40 parts, Borneolum Syntheticum 22 parts and Camphora 10.
Preparation method is identical with embodiment 1.
Embodiment 33:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 29 parts, Semen Persicae, 29 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 30 parts, 98 parts, Herba Ephedrae, Herba speranskiae tuberculatae 96 parts, Rhizoma Drynariae 37 parts, Eupolyphaga Seu Steleophaga 39 parts, Rhizoma Corydalis 31 parts, Lignum Sappan 34 parts, Fructus Gardeniae 39 parts, the Radix Aucklandiae 34 parts, Borneolum Syntheticum 27 parts and Camphora 10.
Preparation method is identical with embodiment 4.
Embodiment 34:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 32 parts, Semen Persicae, 28 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 22 parts, 92 parts, Herba Ephedrae, Herba speranskiae tuberculatae 90 parts, Rhizoma Drynariae 30 parts, Eupolyphaga Seu Steleophaga 30 parts, Rhizoma Corydalis 35 parts, Lignum Sappan 38 parts, Fructus Gardeniae 43 parts, the Radix Aucklandiae 46 parts, Borneolum Syntheticum 15 parts and Camphora 12.
Preparation method is identical with embodiment 4.
Embodiment 35:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 40 parts, Semen Persicae, 40 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 30 parts, 110 parts, Herba Ephedrae, Herba speranskiae tuberculatae 100 parts, Rhizoma Drynariae 38 parts, Eupolyphaga Seu Steleophaga 40 parts, Rhizoma Corydalis 30 parts, Lignum Sappan 35 parts, Fructus Gardeniae 40 parts, the Radix Aucklandiae 40 parts, Borneolum Syntheticum 19 parts and Camphora 18.
Preparation method is identical with embodiment 4.
Embodiment 36:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 35 parts, Semen Persicae, 40 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 25 parts, 120 parts, Herba Ephedrae, Herba speranskiae tuberculatae 118 parts, Rhizoma Drynariae 30 parts, Eupolyphaga Seu Steleophaga 28 parts, Rhizoma Corydalis 40 parts, Lignum Sappan 40 parts, Fructus Gardeniae 38 parts, the Radix Aucklandiae 47 parts and Borneolum Syntheticum 30 parts.
Preparation method is identical with embodiment 1.
Embodiment 37:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 37 parts, Semen Persicae, 38 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 24 parts, 105 parts, Herba Ephedrae, Herba speranskiae tuberculatae 100 parts, Rhizoma Drynariae 26 parts, Eupolyphaga Seu Steleophaga 25 parts, Rhizoma Corydalis 30 parts, Lignum Sappan 33 parts, Fructus Gardeniae 39 parts, the Radix Aucklandiae 45 parts and Borneolum Syntheticum 25 parts.
Preparation method is identical with embodiment 1.
Embodiment 38:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 35 parts, Semen Persicae, 35 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 15 parts, 106 parts, Herba Ephedrae, Herba speranskiae tuberculatae 102 parts, Rhizoma Drynariae 25 parts, Eupolyphaga Seu Steleophaga 25 parts, Rhizoma Corydalis 32 parts, Lignum Sappan 30 parts, Fructus Gardeniae 32 parts, the Radix Aucklandiae 43 parts and Borneolum Syntheticum 17 parts.
Preparation method is identical with embodiment 4.
Embodiment 39:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 36 parts, Semen Persicae, 37 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 27 parts, 116 parts, Herba Ephedrae, Herba speranskiae tuberculatae 116 parts, Rhizoma Drynariae 31 parts, Eupolyphaga Seu Steleophaga 31 parts, Rhizoma Corydalis 31 parts, Lignum Sappan 35 parts, Fructus Gardeniae 36 parts, the Radix Aucklandiae 37 parts, Borneolum Syntheticum 24 parts and Camphora 20.
Preparation method is identical with embodiment 4.
Embodiment 40:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 25 parts, Semen Persicae, 25 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 30 parts, 90 parts, Herba Ephedrae, Herba speranskiae tuberculatae 98 parts, Rhizoma Drynariae 30 parts, Eupolyphaga Seu Steleophaga 30 parts, Rhizoma Corydalis 30 parts, Lignum Sappan 35 parts, Fructus Gardeniae 45 parts, the Radix Aucklandiae 45 parts, Borneolum Syntheticum 20 parts and Camphora 16.
Preparation method is identical with embodiment 4.
Embodiment 41:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 30 parts, Semen Persicae, 30 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 22 parts, 100 parts, Herba Ephedrae, Herba speranskiae tuberculatae 100 parts, Rhizoma Drynariae 25 parts, Eupolyphaga Seu Steleophaga 25 parts, Rhizoma Corydalis 35 parts, Lignum Sappan 35 parts, Fructus Gardeniae 50 parts, the Radix Aucklandiae 50 parts and Borneolum Syntheticum 25 parts.
Preparation method is identical with embodiment 4.
Embodiment 42:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 35 parts, Semen Persicae, 30 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 25 parts, 115 parts, Herba Ephedrae, Herba speranskiae tuberculatae 100 parts, Rhizoma Drynariae 35 parts, Eupolyphaga Seu Steleophaga 35 parts, Rhizoma Corydalis 36 parts, Lignum Sappan 36 parts, Fructus Gardeniae 45 parts, the Radix Aucklandiae 40 parts and Borneolum Syntheticum 25 parts.
Preparation method is identical with embodiment 1.
Embodiment 43:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 40 parts, Semen Persicae, 40 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 30 parts, 120 parts, Herba Ephedrae, Herba speranskiae tuberculatae 120 parts, Rhizoma Drynariae 35 parts, Eupolyphaga Seu Steleophaga 40 parts, Rhizoma Corydalis 35 parts, Lignum Sappan 40 parts, Fructus Gardeniae 50 parts, the Radix Aucklandiae 50 parts, Borneolum Syntheticum 28 parts and Camphora 16.
Preparation method is identical with embodiment 1.
Embodiment 44:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 25 parts, Semen Persicae, 35 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 20 parts, 107 parts, Herba Ephedrae, Herba speranskiae tuberculatae 112 parts, Rhizoma Drynariae 32 parts, Eupolyphaga Seu Steleophaga 32 parts, Rhizoma Corydalis 30 parts, Lignum Sappan 30 parts, Fructus Gardeniae 36 parts, the Radix Aucklandiae 34 parts and Borneolum Syntheticum 22 parts.
Preparation method is identical with embodiment 1.
Embodiment 45:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 30 parts, Semen Persicae, 30 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 25 parts, 95 parts, Herba Ephedrae, Herba speranskiae tuberculatae 95 parts, Rhizoma Drynariae 36 parts, Eupolyphaga Seu Steleophaga 35 parts, Rhizoma Corydalis 32 parts, Lignum Sappan 32 parts, Fructus Gardeniae 40 parts, the Radix Aucklandiae 40 parts, Borneolum Syntheticum 15 parts and Camphora 14.
Preparation method is identical with embodiment 4.
Embodiment 46:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 35 parts, Semen Persicae, 35 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 20 parts, 100 parts, Herba Ephedrae, Herba speranskiae tuberculatae 100 parts, Rhizoma Drynariae 30 parts, Eupolyphaga Seu Steleophaga 30 parts, Rhizoma Corydalis 30 parts, Lignum Sappan 30 parts, Fructus Gardeniae 38 parts, the Radix Aucklandiae 42 parts and Borneolum Syntheticum 21 parts.
Preparation method is identical with embodiment 4.
Embodiment 47:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 35 parts, Semen Persicae, 30 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 15 parts, 105 parts, Herba Ephedrae, Herba speranskiae tuberculatae 105 parts, Rhizoma Drynariae 35 parts, Eupolyphaga Seu Steleophaga 35 parts, Rhizoma Corydalis 31 parts, Lignum Sappan 31 parts, Fructus Gardeniae 45 parts, the Radix Aucklandiae 45 parts, Borneolum Syntheticum 28 parts and Camphora 10.
Preparation method is identical with embodiment 4.
Embodiment 48:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 26 parts, Semen Persicae, 26 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 18 parts, 82 parts, Herba Ephedrae, Herba speranskiae tuberculatae 85 parts, Rhizoma Drynariae 25 parts, Eupolyphaga Seu Steleophaga 25 parts, Rhizoma Corydalis 30 parts, Lignum Sappan 30 parts, Fructus Gardeniae 40 parts, the Radix Aucklandiae 40 parts, Borneolum Syntheticum 18 parts and Camphora 15.
Preparation method is identical with embodiment 4.
Embodiment 49:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 30 parts, Semen Persicae, 35 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 20 parts, 88 parts, Herba Ephedrae, Herba speranskiae tuberculatae 92 parts, Rhizoma Drynariae 32 parts, Eupolyphaga Seu Steleophaga 32 parts, Rhizoma Corydalis 33 parts, Lignum Sappan 33 parts, Fructus Gardeniae 38 parts, the Radix Aucklandiae 38 parts, Borneolum Syntheticum 20 parts and Camphora 13.
Preparation method is identical with embodiment 4.
Embodiment 50:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 37 parts, Semen Persicae, 37 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 26 parts, 96 parts, Herba Ephedrae, Herba speranskiae tuberculatae 92 parts, Rhizoma Drynariae 34 parts, Eupolyphaga Seu Steleophaga 35 parts, Rhizoma Corydalis 34 parts, Lignum Sappan 34 parts, Fructus Gardeniae 42 parts, the Radix Aucklandiae 42 parts and Borneolum Syntheticum 19 parts.
Preparation method is identical with embodiment 1.
Embodiment 51:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 38 parts, Semen Persicae, 30 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 25 parts, 98 parts, Herba Ephedrae, Herba speranskiae tuberculatae 114 parts, Rhizoma Drynariae 35 parts, Eupolyphaga Seu Steleophaga 35 parts, Rhizoma Corydalis 36 parts, Lignum Sappan 36 parts, Fructus Gardeniae 45 parts, the Radix Aucklandiae 45 parts, Borneolum Syntheticum 15 parts and Camphora 15.
Preparation method is identical with embodiment 1.
Embodiment 52:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 32 parts, Semen Persicae, 32 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 26 parts, 102 parts, Herba Ephedrae, Herba speranskiae tuberculatae 102 parts, Rhizoma Drynariae 35 parts, Eupolyphaga Seu Steleophaga 35 parts, Rhizoma Corydalis 31 parts, Lignum Sappan 31 parts, Fructus Gardeniae 45 parts, the Radix Aucklandiae 45 parts and Borneolum Syntheticum 28 parts.
Preparation method is identical with embodiment 1.
Embodiment 53:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 34 parts, Semen Persicae, 38 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 30 parts, 100 parts, Herba Ephedrae, Herba speranskiae tuberculatae 106 parts, Rhizoma Drynariae 36 parts, Eupolyphaga Seu Steleophaga 38 parts, Rhizoma Corydalis 39 parts, Lignum Sappan 39 parts, Fructus Gardeniae 35 parts, the Radix Aucklandiae 35 parts, Borneolum Syntheticum 23 parts and Camphora 13.
Preparation method is identical with embodiment 4.
Embodiment 54:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 31 parts, Semen Persicae, 32 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 20 parts, 110 parts, Herba Ephedrae, Herba speranskiae tuberculatae 108 parts, Rhizoma Drynariae 37 parts, Eupolyphaga Seu Steleophaga 37 parts, Rhizoma Corydalis 40 parts, Lignum Sappan 40 parts, Fructus Gardeniae 30 parts, the Radix Aucklandiae 30 parts and Borneolum Syntheticum 26 parts.
Preparation method is identical with embodiment 4.
Embodiment 55:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, be made up of the crude drug of following weight portion: 34 parts, Semen Persicae, 36 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 22 parts, 110 parts, Herba Ephedrae, Herba speranskiae tuberculatae 118 parts, Rhizoma Drynariae 30 parts, Eupolyphaga Seu Steleophaga 32 parts, Rhizoma Corydalis 32 parts, Lignum Sappan 35 parts, Fructus Gardeniae 38 parts, the Radix Aucklandiae 38 parts and Borneolum Syntheticum 20 parts.
Preparation method is identical with embodiment 4.
Embodiment 56:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 25 parts, Semen Persicae, 33 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 17 parts, 115 parts, Herba Ephedrae, Herba speranskiae tuberculatae 116 parts, Rhizoma Drynariae 27 parts, Eupolyphaga Seu Steleophaga 27 parts, Rhizoma Corydalis 36 parts, Lignum Sappan 36 parts, Fructus Gardeniae 33 parts, the Radix Aucklandiae 33 parts, Borneolum Syntheticum 16 parts and Camphora 17.
Preparation method is identical with embodiment 4.
Embodiment 57:
The present invention treats the bone wound medicine (gushangling) spray of soft tissue injury and osteoarticular injury disease, is made up of the crude drug of following weight portion: 28 parts, Semen Persicae, 33 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 17 parts, 102 parts, Herba Ephedrae, Herba speranskiae tuberculatae 118 parts, Rhizoma Drynariae 27 parts, Eupolyphaga Seu Steleophaga 27 parts, Rhizoma Corydalis 36 parts, Lignum Sappan 36 parts, Fructus Gardeniae 33 parts, the Radix Aucklandiae 33 parts, Borneolum Syntheticum 16 parts and Camphora 19.
Preparation method is identical with embodiment 4.
The present invention is not limited to above-mentioned detailed description of the invention, and those skilled in the art also can make multiple change accordingly, but to be anyly equal to the present invention or similar change all should be encompassed in the scope of the claims in the present invention.
Claims (6)
1. a bone wound medicine (gushangling) spray, is characterized in that, described bone wound medicine (gushangling) spray is made primarily of the crude drug of following weight portion: 25 ~ 40 parts, Semen Persicae, 25 ~ 40 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 15 ~ 30 parts, 80 ~ 120 parts, Herba Ephedrae, Herba speranskiae tuberculatae 80 ~ 120 parts, Rhizoma Drynariae 25 ~ 40 parts, Eupolyphaga Seu Steleophaga 25 ~ 40 parts, Rhizoma Corydalis 30 ~ 40 parts, Lignum Sappan 30 ~ 40 parts, Fructus Gardeniae 30 ~ 50 parts, the Radix Aucklandiae 30 ~ 50 parts and Borneolum Syntheticum 10 ~ 30 parts.
2. bone wound medicine (gushangling) spray according to claim 1, is characterized in that, the primary raw material medicine of described bone wound medicine (gushangling) spray is 25.1 ~ 29.9 parts, Semen Persicae, 25.1 ~ 29.9 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 15.1 ~ 19.9 parts, 80.1 ~ 94.9 parts, Herba Ephedrae, Herba speranskiae tuberculatae 80.1 ~ 94.9 parts, Rhizoma Drynariae 25.1 ~ 29.9 parts, Eupolyphaga Seu Steleophaga 25.1 ~ 29.9 parts, Rhizoma Corydalis 30.1 ~ 33 parts, Lignum Sappan 30.1 ~ 33 parts, Fructus Gardeniae 30.1 ~ 37 parts, the Radix Aucklandiae 30.1 ~ 37 parts and Borneolum Syntheticum 10.1 ~ 17 parts.
3. bone wound medicine (gushangling) spray according to claim 1, is characterized in that, the primary raw material medicine of described bone wound medicine (gushangling) spray is 30.1 ~ 34.9 parts, Semen Persicae, 30.1 ~ 34.9 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 20.1 ~ 24.9 parts, 95.1 ~ 109.9 parts, Herba Ephedrae, Herba speranskiae tuberculatae 95.1 ~ 109.9 parts, Rhizoma Drynariae 30.1 ~ 34.9 parts, Eupolyphaga Seu Steleophaga 30.1 ~ 34.9 parts, Rhizoma Corydalis 33 ~ 36 parts, Lignum Sappan 33 ~ 36 parts, Fructus Gardeniae 37 ~ 43 parts, the Radix Aucklandiae 37 ~ 43 parts and Borneolum Syntheticum 17 ~ 23 parts.
4. bone wound medicine (gushangling) spray according to claim 1, is characterized in that, the primary raw material medicine of described bone wound medicine (gushangling) spray is 35.1 ~ 40 parts, Semen Persicae, 35.1 ~ 40 parts, Rhizoma Curcumae Longae, Sanguis Draxonis 25.1 ~ 30 parts, 110.1 ~ 120 parts, Herba Ephedrae, Herba speranskiae tuberculatae 110.1 ~ 120 parts, Rhizoma Drynariae 35.1 ~ 40 parts, Eupolyphaga Seu Steleophaga 35.1 ~ 40 parts, Rhizoma Corydalis 36 ~ 40 parts, Lignum Sappan 36 ~ 40 parts, Fructus Gardeniae 43 ~ 50 parts, the Radix Aucklandiae 43 ~ 50 parts and Borneolum Syntheticum 23 ~ 30 parts.
5. the bone wound medicine (gushangling) spray according to any one of Claims 1 to 4, is characterized in that, the preparation method of described bone wound medicine (gushangling) spray comprises the following steps:
(1) according to the crude drug proportioning of the bone wound medicine (gushangling) spray described in any one of Claims 1 to 4, take various crude drug, various crude drug is put into saucepan, add 2500 ~ 3000ml water, soak 10 ~ 12 hours, be heated to boiling, boil 40 ~ 50 minutes, filter, by medicinal residues elimination, obtain the medicinal liquid 1800 ~ 2200ml boiled;
(2) medicinal liquid is first used 250 mesh screen twice, and then with 300 mesh screen twice, collect medicinal liquid, be bone wound medicine (gushangling) spray.
6. bone wound medicine (gushangling) spray according to claim 5, is characterized in that, the preparation method of described bone wound medicine (gushangling) spray is further comprising the steps of:
The medicinal liquid of collection is cooled to room temperature, in medicinal liquid weight 1 ‰ ~ 1.5 ‰ ratio add azone, obtain bone wound medicine (gushangling) spray after being uniformly mixed.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105396052A (en) * | 2015-11-30 | 2016-03-16 | 济南舜祥医药科技有限公司 | Spray for treating bone fracture and preparation method thereof |
| CN105663549A (en) * | 2016-03-14 | 2016-06-15 | 冯翠军 | Traditional Chinese medicinal composition for treating bone injuries and preparation method of traditional Chinese medicinal composition |
| CN107126542A (en) * | 2017-05-23 | 2017-09-05 | 汪建军 | A kind of bone fracture spray and preparation method thereof |
| CN107951970A (en) * | 2017-12-08 | 2018-04-24 | 蔡联英 | Treat the preparation method of acute injury of tendon and muscle external application Traditional Chinese ointments |
| CN114699363A (en) * | 2022-06-08 | 2022-07-05 | 江西中医药大学附属医院 | Traditional Chinese medicine wax mud for osteoarthritis and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1583062A (en) * | 2004-05-28 | 2005-02-23 | 徐玉成 | Medicinal ointment for bone injury |
| CN100998799A (en) * | 2006-12-27 | 2007-07-18 | 陈玉龙 | Chinese medicinal preparation for treating fracture, traumatic injury |
| CN102988657A (en) * | 2012-11-26 | 2013-03-27 | 高彦龙 | Plaster for treating fracture and traumatic injury and preparation method of plaster |
-
2014
- 2014-09-23 CN CN201410489241.7A patent/CN104258278B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1583062A (en) * | 2004-05-28 | 2005-02-23 | 徐玉成 | Medicinal ointment for bone injury |
| CN100998799A (en) * | 2006-12-27 | 2007-07-18 | 陈玉龙 | Chinese medicinal preparation for treating fracture, traumatic injury |
| CN102988657A (en) * | 2012-11-26 | 2013-03-27 | 高彦龙 | Plaster for treating fracture and traumatic injury and preparation method of plaster |
Non-Patent Citations (2)
| Title |
|---|
| 李国柱: "灵仙伤痛膏贴敷治疗跌打损伤158例分析", 《中国民间疗法》 * |
| 郭秀红: "中药薰洗治疗骨折康复病人的效果评价", 《河北中医药学报》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105396052A (en) * | 2015-11-30 | 2016-03-16 | 济南舜祥医药科技有限公司 | Spray for treating bone fracture and preparation method thereof |
| CN105663549A (en) * | 2016-03-14 | 2016-06-15 | 冯翠军 | Traditional Chinese medicinal composition for treating bone injuries and preparation method of traditional Chinese medicinal composition |
| CN107126542A (en) * | 2017-05-23 | 2017-09-05 | 汪建军 | A kind of bone fracture spray and preparation method thereof |
| CN107951970A (en) * | 2017-12-08 | 2018-04-24 | 蔡联英 | Treat the preparation method of acute injury of tendon and muscle external application Traditional Chinese ointments |
| CN114699363A (en) * | 2022-06-08 | 2022-07-05 | 江西中医药大学附属医院 | Traditional Chinese medicine wax mud for osteoarthritis and preparation method thereof |
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| CN104258278B (en) | 2017-05-03 |
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