CN104257952A - 一种治疗鸡球虫病的中药组合物 - Google Patents
一种治疗鸡球虫病的中药组合物 Download PDFInfo
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- CN104257952A CN104257952A CN201410563616.XA CN201410563616A CN104257952A CN 104257952 A CN104257952 A CN 104257952A CN 201410563616 A CN201410563616 A CN 201410563616A CN 104257952 A CN104257952 A CN 104257952A
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Abstract
本发明属于兽药技术领域,特别公开了一种治疗鸡球虫病的中药组合物。该中药组合物,其活性成分由以下重量份数的原料制成:鸦胆子25-35份、穿心莲25-35份、凤尾草25-35份、地锦草20-35份、苦参15-20份、柴胡35-40份、地骨皮12-20份、白头翁23-27、苦楝皮10-20份、苍术15-25份、大黄10-15份、雷丸10-15份、海芋15-30份、绞股蓝13-17份、枳壳10-20份、虎杖5-15份、刺五加15-20份、黄连25-30份。该中药组合物能很好的杀灭鸡球虫,临床应用治愈率高,具有针对性强、疗效显著、鸡不易产生耐药性、药物无残留、无刺激性、安全可靠等特点,制备简单,可在养鸡业中广泛应用。
Description
(一)技术领域
本发明属于兽药技术领域,特别涉及一种治疗鸡球虫病的中药组合物。
(二)背景技术
鸡球虫病是鸡常见且危害十分严重的寄生虫病,是由一种或多种球虫引起的急性流行性寄生虫病。它造成的经济损失是惊人的。10~30日龄的雏鸡或35~60日龄的青年鸡的发病率和致死率可高达80%。病愈的雏鸡生长受阻,增重缓慢;成年鸡一般不发病,但为带虫者,增重和产蛋能力降低,是传播球虫病的重要病源。因此,鸡球虫病是造成现代养禽业经济损失最大的寄生虫病之一,为了更好的控制该病的发生,世界各国对鸡球虫病都进行了深入细致的研究。目前,虽然国内外学者对球虫疫苗的研究有了一定的进展,但仍存在诸多问题,短期内还难以推广应用。临床上仍然以化学药物防治为主。然而,化学药物的长期使用容易造成效果不佳的情况,近年开始应用中草药防治鸡球虫病。中草药在该病的防治中相对化学药物治疗具有不易产生耐药性、毒副作用小且能促进机体生长等优点,但是由于当前针对鸡球虫病的中药组合物种类繁多,大多处于摸索研究阶段,治疗效果不尽相同,能够实际广泛应用于畜禽业尤其是养鸡场的则很少。
(三)发明内容
本发明为了弥补现有技术的不足,提供了一种针对性强、配方合理、疗效显著、不产生耐药性、药物无残留且制备简单的治疗鸡球虫病的中药组合物,可广泛用于养鸡业。
本发明是通过如下技术方案实现的:
一种治疗鸡球虫病的中药组合物,其活性成分由以下重量份数的原料制成:
鸦胆子25-35份、穿心莲25-35份、凤尾草25-35份、地锦草20-35份、苦参15-20份、柴胡35-40份、地骨皮12-20份、白头翁23-27、苦楝皮10-20份、苍术15-25份、大黄10-15份、雷丸10-15份、海芋15-30份、绞股蓝13-17份、枳壳10-20份、虎杖5-15份、刺五加15-20份、黄连25-30份。
其优选的各活性成分的重量配比为:
鸦胆子30份、穿心莲30份、凤尾草30份、地锦草28份,苦参18份、柴胡38份、地骨皮16份、白头翁25份、苦楝皮15份、苍术20份、大黄12份、雷丸12份、海芋22份、绞股蓝15份、枳壳15份、虎杖10份,刺五加17份,黄连27份。
制备方法:取上述重量份的原料混合,粉碎研磨为细末,炼蜜为丸,药丸黄豆粒大。
用法用量:每日服用两次,每次服用量为小鸡1粒,大鸡3粒,连服3天为一疗程,一般1-3个疗程即可治愈。
本发明所采用的各活性成分的药用性能如下所示:
鸦胆子:性味:苦,寒。有小毒。功效:清热解毒、止痢截疟,腐蚀赘疣。治痢疾疟疾、外治赘疣、鸡眼。
穿心莲:味苦,性寒。功效:清热解毒,凉血,消肿,燥湿。主治:感冒发热,咽喉肿痛,口舌生疮,顿咳劳嗽,泄泻痢疾,热淋涩痛,痈肿疮疡,急性菌痢,胃肠炎,感冒,流脑,气管炎,肺炎,百日咳,肺结核,肺脓疡,胆囊炎,高血压,鼻衄,水火烫伤,毒蛇咬伤。穿心莲在临床上曾应用于多种感染性疾病,均有不同程度的疗效。
凤尾草:性味:苦、寒。功效:败毒抗癌、清热除湿、凉血止血。其煎剂对金黄色葡萄球菌、溶血性链球菌、福氏痢疾杆菌、伤寒杆菌均有抑制作用。
地锦草:性味:味辛;性平。归经:肺;肝;胃;大肠;膀胱经。功效分类:活血药;止血药;清热解毒药。功能主治:清热解毒,活血,止血,利湿。治菌痢,肠炎,咳血,吐血,便血,崩漏,外伤出血,湿热黄疸,痈肿疔疮,跌打肿痛。
苦参:性味:苦,寒。归经:归心、肝、胃、大肠、膀胱经。功能主治:清热燥湿,杀虫,利尿。用于热痢,便血,黄疸尿闭,赤白带下,阴肿阴痒,湿疹,湿疮,皮肤瘙痒,疥癣麻风。
柴胡:性味:苦平、归经、入肝、胆经。功能:发表、退热、疏肝、解郁、升阳。现代药理研究证明,柴胡具有1、解热、退热作用平稳可靠;2、良好的镇痛作用和较强的止咳作用;3、抗菌,对结核杆菌有抑制作用;4、抗肝损伤作用;5、抗病毒,对流感病毒有强烈的抑制作用。主治:疏散退热,升阳疏肝。用于感冒发热,寒热往来、疟疾,肝郁气滞,胸肋胀痛,脱肛。
地骨皮:性味:甘,寒。归经:归肺、肝、肾经。功能主治:凉血除蒸,清肺降火。用于阴虚潮热,骨蒸盗汗,肺热咳嗽,咯血,衄血,内热消渴。
白头翁:性味:苦,寒。归经:归胃、大肠经。功能主治:清热解毒,凉血止痢。用于热毒血痢,阴痒带下,阿米巴痢。
苦楝皮:性味:苦,寒;有毒。归经:归肝、脾、胃经。功能主治:驱虫,疗癣。用于蛔蛲虫病,虫积腹痛;外治疥癣瘙痒。
苍术:性味:辛、苦,温。归经:归脾、胃、肝经。功能主治:燥湿健脾,祛风散寒,明目。用于脘腹胀满,泄泻,水肿,脚气痿躄,风湿痹痛,风寒感冒,夜盲。
大黄:性味:苦,寒。归经:归脾、胃、大肠、肝、心包经。功能主治:泻热通肠,凉血解毒,逐瘀通经。用于实热便秘,积滞腹痛,泻痢不爽,湿热黄疸,血热吐衄,目赤,咽肿,肠痈腹痛,痈肿疔疮,跌打损伤,外治水火烫伤;上消化道出血。酒大黄善清上焦血分热毒。用于目赤咽肿,齿龈肿痛。熟大黄泻下力缓,泻火解毒。用于火毒疮疡。大黄炭凉血化瘀止血。用于血热有瘀出血症。
雷丸:性味:微苦,寒。归经:归胃、大肠经。功能主治:杀虫消积,用于绦虫、钩虫、蛔虫病,虫积腹痛。
海芋:性味:微辛、涩,寒。有毒。功能主治:清热解毒,消肿。用于感冒,肺结核,肠伤寒。
绞股蓝:性味:苦,寒。功能主治:清热解毒,止咳祛痰。用于慢性支气管炎,传染性肝炎,肾炎炎,胃肠炎。
枳壳:性味:苦、辛、酸,温。归经:归脾、胃经。功能主治:理气宽中,行滞消胀。用于胸胁气滞,胀满疼痛,食积不化,痰饮内停;胃下垂,脱肛。
虎杖:性味:微苦,微寒。归经:归肝、胆、肺经。功能主治:祛风利湿,散瘀定痛,止咳化痰。用于关节痹痛,湿热黄疸,症瘕,水火烫伤,跌扑损伤,痈肿疮毒,咳嗽痰多。
刺五加:性味:辛、微苦,温。归经:归脾、肾、心经。功能主治:益气健脾,补肾安神。用于脾肾阳虚,体虚乏力,食欲不振。
黄连:性味:苦,寒。归经:归心、脾、胃、肝、胆、大肠经。功能主治:清热燥湿,泻火解毒。用于湿热痞满,呕吐吞酸,泻痢,黄疸,高热神昏,心火亢盛,心烦不寐,血热吐衄,目赤,消渴,痈肿疔疮。酒黄连善清上焦火热。用于目赤,口疮。姜黄连清胃和胃止呕。用于寒热互结,湿热中阻,痞满呕吐。萸黄连舒肝和胃止呕。用于肝胃不和,呕吐吞酸。
本发明的中药专门用于治疗鸡球虫病,以鸦胆子、穿心莲、苦参、柴胡、白头翁、大黄、海芋、绞股蓝、黄连等,泻下攻积,清热解毒;以苦楝皮、雷丸等驱虫消积,驱除鸡球虫;以凤尾草、地锦草、地骨皮等凉血止血、补血和血达到收敛解毒的作用;同时配以虎杖祛风利湿,配以苍术、枳壳、虎杖、刺五加、黄连等健脾益气、消除食积不化,提高鸡群食欲。将以上多种药物适当配合,利用其相互间的协同或抵抗作用,发挥药效,提高疗效,不但可以抑制病原球虫的发育或杀灭球虫,而且可以调节动物机体免疫,改善病鸡食欲不振、精神萎靡的状态,并对病变的组织细胞进行修复,以达到清热解毒、杀虫止痢、养血生津的功效,更利于鸡群疾病的消除及鸡群生长和产蛋能力的提升,具有针对性强、疗效显著、鸡不易产生耐药性、药物无残留、无刺激性、安全可靠等特点,治愈率高达92%以上,且制备简单,可以广泛用于养鸡业。
(四)具体实施方式
下面结合实施例对本发明作进一步说明,但本发明并不局限于此,实施例中的制备方法均为常规制备方法,不再详述。
实施例1:
该治疗鸡球虫病的中药组合物,其活性成分由以下重量的原料制成:
鸦胆子30g、穿心莲30g、凤尾草30g、地锦草28g、苦参18g、柴胡38g、地骨皮16g、白头翁25g、苦楝皮15g、苍术20g、大黄12g、雷丸12g、海芋22g、绞股蓝15g、枳壳15g、虎杖10g、刺五加17g、黄连27g。
将上述药物按重量份混合,粉碎研磨为细末,炼蜜为丸,药丸黄豆粒大,制备方法为现有技术,不再详述。
用法用量:每日服用两次,每次服用量为小鸡1粒,大鸡3粒,连服3天为一疗程,一般1-3个疗程即可治愈。
实施例2:
该治疗鸡球虫病的中药组合物,其活性成分由以下重量的原料制成:
鸦胆子25g、穿心莲25g、凤尾草25g、地锦草20g、苦参15g、柴胡35g、地骨皮12g、白头翁23g、苦楝皮10g、苍术15g、大黄10g、雷丸10g、海芋15g、绞股蓝13g、枳壳10g、虎杖5g、刺五加15g、黄连25g。
制备方法与用法用量同实施例1。
实施例3:
该治疗鸡球虫病的中药组合物,其活性成分由以下重量的原料制成:
鸦胆子35g、穿心莲35g、凤尾草35g、地锦草35g、苦参20g、柴胡40g、地骨皮20g、白头翁27g、苦楝皮20g、苍术25g、大黄15g、雷丸15g、海芋30g、绞股蓝17g、枳壳20g、虎杖15g、刺五加20g、黄连30g。
制备方法与用法用量同实施例1。
实施例4:
该治疗鸡球虫病的中药组合物,其活性成分由以下重量的原料制成:
鸦胆子28g、穿心莲28g、凤尾草28g、地锦草24g、苦参16g、柴胡37g、地骨皮14g、白头翁24g、苦楝皮12g、苍术17g、大黄11g、雷丸11g、海芋18g、绞股蓝14g、枳壳12g、虎杖7g、刺五加16g、黄连26g。
制备方法与用法用量同实施例1。
实施例5:
该治疗鸡球虫病的中药组合物,其活性成分由以下重量的原料制成:
鸦胆子32g、穿心莲32g、凤尾草32g、地锦草32g、苦参19g、柴胡39g、地骨皮18g、白头翁26g、苦楝皮18g、苍术22g、大黄14g、雷丸13g、海芋26g、绞股蓝16g、枳壳18g、虎杖12g,刺五加18g、黄连29g。
制备方法与用法用量同实施例1。
临床试验观察:
(1)山东省济南市历城区某养殖场饲养蛋鸡1000只,25日龄时出现下述症状:精神萎靡,拥挤在一起,翅膀下垂,羽毛逆立,闭眼瞌睡,下痢,排出带血液的稀粪,食欲不振,鸡冠苍白,鉴定为鸡球虫病,这种状况3天已有120只鸡死亡,通过及时采用本发明中药组合物,对所有病鸡喂服,采用小鸡1粒、大鸡3粒,每日2次的喂服剂量,3天为一疗程,连服2个疗程后病情得以控制。治疗结束死亡病鸡71只,治愈809只,治愈率92%,未再复发。
(2)山东省济南市商河县某养鸡场的蛋鸡1400只,在60日龄时出现冠苍白,食欲减少,精神萎靡,消瘦,羽毛蓬松,下痢,两脚无力,瘫倒不起,鉴定为鸡球虫病并及时采用本发明的中药治疗,采用小鸡1粒、大鸡3粒,每日2次的喂服剂量,连服9天后病情得以控制。治疗结束死亡病鸡98只,治愈1302只,治愈率93%,未再复发。
Claims (2)
1.一种治疗鸡球虫病的中药组合物,其特征是:其活性成分由以下重量份数的原料制成:
鸦胆子25-35份、穿心莲25-35份、凤尾草25-35份、地锦草20-35份、苦参15-20份、柴胡35-40份、地骨皮12-20份、白头翁23-27、苦楝皮10-20份、苍术15-25份、大黄10-15份、雷丸10-15份、海芋15-30份、绞股蓝13-17份、枳壳10-20份、虎杖5-15份、刺五加15-20份、黄连25-30份。
2.根据权利要求1所述的一种治疗鸡球虫病的中药组合物,其特征是:其活性成分由以下重量份数的原料制成:
鸦胆子30份、穿心莲30份、凤尾草30份、地锦草28份,苦参18份、柴胡38份、地骨皮16份、白头翁25份、苦楝皮15份、苍术20份、大黄12份、雷丸12份、海芋22份、绞股蓝15份、枳壳15份、虎杖10份,刺五加17份,黄连27份。
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