CN104257371A - Research of dynamic blood pressure detection and calibration method of radial artery - Google Patents

Abstract

The invention relates to a dynamic blood pressure detection and calibration method of a radial artery. The method comprises the following steps: measuring a blood pressure value BP1 to perform first calibration by using oscillography; measuring a blood pressure value BP2 to perform second calibration by using correlation of an electrocardiosignal, a pulse wave signal and human arterial pressure; finally performing continuous monitoring of blood pressure by using the linear relation between pulse wave transmission time difference PWT of two different parts on a wrist and the human arterial blood pressure which are measured at the same time.

Description

Research on a Radial Artery Ambulatory Blood Pressure Detection and Calibration Method

technical field

The present invention generally relates to the research of a radial artery dynamic blood pressure detection and calibration method, and in particular to a device for continuous monitoring of blood pressure by using the linear relationship between the pulse wave transit time difference PWT and the human arterial blood pressure after two calibrations. method.

Background technique

Today, hypertension has become the most common chronic disease of the cardiovascular system and one of the global public health problems. Existing families and hospitals commonly used blood pressure measuring devices are mainly based on the Korotkoff sound method and the oscillometric method. Although it can accurately measure the blood pressure value, it needs to use a cuff during the measurement process. There is a process of inflation and deflation of the cuff, so it can only measure the blood pressure value at a certain moment, and because of the "white coat" phenomenon Existence, so commonly used blood pressure measuring devices will have some errors in the process of blood pressure measurement.

At present, because the ECG R wave is easier to be measured, the blood pressure measurement technology combining ECG and PPG has become one of the commonly used non-invasive measurement methods of arterial blood pressure. This method uses the same arterial pulse wave to transmit from the ECG R wave to the pulse wave feature point The time interval between PTT to estimate blood pressure. However, in order to obtain the PPG at the fingertip, a finger clip-type PPG sensor is usually used, and its wires are exposed outside, which brings inconvenience to the measurement.

The blood pressure measurement technology combined with two-channel PPG has also become one of the commonly used non-invasive blood pressure measurement methods. The blood pressure measurement technology combining two-way PPG is to place two PPG sensors on two different parts of the human body, such as fingers and toes, fingers and ears, fingers and upper arms, fingers and wrists, etc. The blood pressure measurement technology combined with two-way PPG can maintain the consistency of the arteries and avoid the influence of the heart and the ejection period. However, since the distance between the two sensors is susceptible to changes in human body movement, it will affect the measurement time interval PTT, thereby causing errors in the estimated blood pressure value.

Using pulse wave transit time PWT to estimate human arterial blood pressure is a non-invasive and continuous blood pressure measurement method. In 1922, someone discovered the relationship between pulse wave transit time PWT and human arterial blood pressure; in 1957, someone proposed the pulse conduction time There is a linear relationship between time PWT and arterial blood pressure, but this relationship is relatively stable only in a certain period of time for an individual, and the proportional coefficient between PWT and BP is different for different individuals, and in previous studies , different individuals are calculated using the same proportional coefficient, there is a certain error.

Contents of the invention

The present invention provides a radial artery ambulatory blood pressure detection and calibration method. The oscillometric method and the method of combining ECG and PPG are used to perform two calibrations, and then use the pulse wave transit time difference PWT and The linear relationship between human arterial blood pressure can be used for continuous monitoring of blood pressure.

In order to achieve the above object, the present invention can use the following scheme:

The invention provides a radial artery dynamic blood pressure detection and calibration method, comprising: a pulse wave signal measurement module; an electrocardiographic signal measurement module; a cuff module; a data storage module; a data analysis and processing module; a display module; Wear it on the wrist, use the microprocessor to control the pump and valve, inflate the cuff, use the principle of oscillometric blood pressure measurement to measure the blood pressure value BP1, and use it as the first calibration blood pressure; then, touch the two pins on the device with your fingers One electrode, and the cuff is inflated at the same time, so that the piezoelectric film is in full contact with the skin, that is, the pulse wave signal and the ECG signal can be measured at the same time, and then the correlation between the pulse wave signal, the ECG signal and the human arterial pressure BP is used. The second calibration blood pressure BP2 is measured; after two blood pressure calibrations, the final blood pressure value is obtained by using the linear relationship between the pulse wave transit time PWT and the human arterial pressure BP.

The present invention relates to a radial artery dynamic blood pressure detection and calibration method, which implements two corrections by two methods before realizing continuous blood pressure measurement, and stores the blood pressure values corrected twice in a data storage module. After two corrections, the pulse waves of different parts of the wrist measured by the 3×2 dot matrix piezoelectric film placed under the display and in contact with the human skin, and then the pulse wave transit time difference is used to finally obtain the human arterial pressure.

Invention effect

The invention relates to a radial artery dynamic blood pressure detection and calibration method, which is characterized in that the continuous measurement of blood pressure is realized at the wrist, the blood pressure measurement at this part is more comfortable, the influence of the change of the receptor position is small, and the measurement error is small; Before realizing the continuous measurement of blood pressure, the commonly used blood pressure measurement method is used to calibrate twice, so that the continuous measurement of blood pressure is more accurate; using 3×2 dot matrix piezoelectric film, because the entire piezoelectric film is relatively small, the measured Different parts of the wrist are closer, so that the measured pulse wave transit time is more accurate, and the obtained continuous blood pressure value is more accurate and the error is small. Compared with the previous continuous blood pressure measurement device, the ambulatory blood pressure continuous measurement and calibration device only needs to be calibrated once before different individuals measure to realize continuous blood pressure measurement. It is easy to operate, can be used anytime and anywhere, has good comfort, and is suitable for long-term wear . At the same time, the technology of combining ECG signal and pulse wave signal is adopted in the second blood pressure calibration, and the monitoring of ECG signal can also be realized by contacting with three electrodes, which is easy to detect cardiovascular and cerebrovascular diseases such as hypertension in time.

Description of drawings

Fig. 1A is a top view of the radial artery ambulatory blood pressure detection and calibration device of the present invention.

Fig. 1B is a side view of the radial artery ambulatory blood pressure detection and calibration device of the present invention.

Fig. 2 is a system block diagram of the radial artery ambulatory blood pressure detection and calibration device of the present invention.

Specific implementation method

The present invention will be described in further detail below in conjunction with the accompanying drawings and specific embodiments, and the implementation scope of the present invention is not limited thereto.

Figure 1A is a top view of the radial artery ambulatory blood pressure detection and calibration device. The device is worn on the left wrist, the display screen is attached to the inner side of the wrist, and the switch is pressed. The microcontroller controls the pump and the valve to inflate and deflate the cuff, thereby obtaining The blood pressure is first calibrated and stored in the data storage module.

Figure 1B is a side view of the radial artery ambulatory blood pressure detection and calibration device. After obtaining the first calibrated blood pressure, the microcontroller controls the pump and valve to deflate the cuff until the pressure sensor fully contacts the human skin, and then 3 The ×2 dot-matrix piezoelectric film can also be fully in contact with the human skin, thereby measuring three pulse wave signals, and storing the obtained three pulse wave signals in the data storage module. Then the fingers of the right hand touch the electrodes 101 and 102 on the side of the device, and the electrodes 103 on the cuff of the device have been in contact with the human body, and the ECG signals are measured by the three-point method. Then analyze and process the ECG signal and the pulse wave signal measured in the second line of the 3×2 dot matrix piezoelectric film in the data analysis and processing module to obtain the second calibrated blood pressure, and store it in the data storage module.

After two blood pressure calibrations, the microcontroller controls to extract the pulse wave signals of the first and third lines of the 3×2 dot matrix piezoelectric film in the data storage module and send them to the data analysis and processing module to obtain the pulse wave transit time difference, In this module, the blood pressure is deduced by using the linear relationship between the pulse wave transit time difference PWT and the human arterial pressure BP, and the blood pressure is displayed on the display screen.

Claims (7)

1. a kind of radial artery ambulatory blood pressure detection and calibration method, it is characterized in that carrying out the continuous measurement of blood pressure after twice calibration, comprises the steps: Using a microcontroller to control the cuff module to obtain the first calibrated blood pressure and store it in the data storage module; After obtaining the first calibrated blood pressure, the microcontroller controls the pump and the valve to deflate the cuff until the pressure sensor fully contacts the human skin, and uses the pulse wave signal measurement module to obtain pulse wave signals from three different parts of the wrist , and store the three pulse wave signals in the data storage module; then use the ECG signal measurement module to obtain the ECG signal, send the obtained ECG signal and one of the pulse wave signals to the data analysis and processing module, and obtain the first 2. Calibrate the blood pressure and store it in the data storage module; After two blood pressure calibrations, send the other two pulse wave data in the data storage module to the data analysis and processing module for analysis and processing based on the linear relationship between the pulse wave transit time PWT and the human arterial blood pressure BP, and then obtain the blood pressure value, and Show it on the display. 2. The wrist type blood pressure continuous measurement calibration device and method according to claim 1, characterized in that: The pulse wave signal measurement module, the ECG signal measurement module, the cuff module, the data storage module, the data analysis and processing module, and the display module are controlled by a microcontroller. 3. radial artery ambulatory blood pressure detection and calibration method according to claim 1, is characterized in that: Its pulse wave signal measurement module is composed of a 3×2 dot matrix piezoelectric film sensor connected to a preamplifier circuit, a bandpass filter circuit, a main amplifier circuit, a 50Hz notch circuit and a level adjustment circuit, and is used to collect and process the pulse. wave signal. 4. radial artery ambulatory blood pressure detection and calibration method according to claim 1, is characterized in that: Its ECG signal measurement module is composed of electrodes 101, 102 and 103 via a preamplifier circuit, a band-pass filter circuit, a main amplifier circuit, a 50Hz notch circuit and a level adjustment circuit, and is used for collecting and processing ECG signals. . 5. radial artery ambulatory blood pressure detection and calibration method according to claim 1, is characterized in that: The cuff module is composed of valve, pump, pressure sensor and cuff; the valve, pump and cuff are controlled by the microprocessor to obtain the first calibration blood pressure; the pressure sensor is to ensure that the gas in the cuff can make 3×2 points The array piezoelectric film can fully contact with the human skin, so that the pulse wave signal can be obtained. 6. radial artery ambulatory blood pressure detection and calibration method according to claim 1, is characterized in that: Its data storage module is used to store the first calibration blood pressure, the second calibration blood pressure, pulse wave signal and electrocardiogram signal, which is convenient for analysis, processing and display of the equipment. 7. radial artery ambulatory blood pressure detection and calibration method according to claim 1, is characterized in that: Its data analysis and processing module is used to process the ECG signal and the pulse wave signal to obtain the second calibration voltage and the final blood pressure value; the principle of obtaining the second calibration blood pressure is based on the relationship between the R wave of the ECG signal and the characteristic point of the pulse wave signal. The correlation between the time difference and the human arterial pressure; the principle of obtaining the final blood pressure value is based on the linear relationship between the pulse wave transit time difference PWT and the human arterial pressure BP.