CN104225287A - Traditional Chinese medicine for treating wind-heat type common cold and preparation method of traditional Chinese medicine - Google Patents

Abstract

The invention discloses a traditional Chinese medicine for treating wind-heat type common cold and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine for treating wind-heat type common cold is characterized by being prepared by combining honeysuckle, fructus forsythiae, mint, fructus arctii, liquorice and the like and being prepared into the following dosage forms such as tablets, capsules, granules and the like. The traditional Chinese medicine is used for treating serious fever, head swelling pain, sweating, swelling and pain in the throat, cough, viscous or yellow phlegm, nasal obstruction and yellow nasal discharge as well as thirst with desire to drink. 20 patients are treated in clinic, the total effective rate is up to 90.00%, and the symptoms of the diseases are remarkably relieved.

Description

A kind of Chinese medicine and preparation method being used for the treatment of anemopyretic cold

Technical field

The present invention relates to a kind of Chinese medicine preparation, particularly a kind of Chinese medicine and preparation method being used for the treatment of anemopyretic cold.

Background technology

Caused by wind heat diseases caused by exogenous pathogenic factor are evil criminal tables of wind heat, lung qi is become estranged, be multiplely born in spring, summer.Spring is windy, and weather turns temperature, therefore wind and heterogeneous the holding concurrently of warm heresy are caused a disease; Summer, outdoor was sultry, and indoor are comparatively nice and cool again, and the indoor and outdoor fluctuation of temperature adds the social life of growing tension, often stays up late, also easy anemopyretic cold.The normally constipation of its cause, belongs to Yangming Channel disease time a lot.Normal conditions are such, and constipation is after two days, sore throat a couple of days, then develop signs of a cold, Here it is anemopyretic cold (also can be diseases caused by exogenous pathogenic factor pathogenic heat, attacking the lung first).

There is document announcement, in the U.S., 3,000,000,000 workaday labor efficiencies approximately will be caused every year to decline because catching a cold; In American students, there is the sick leave of 600,000,000 days because of flu; In working clan, then about to lose 500,000,000 working hours, add the tablet, cough syrup, collunarium liquid medicine, patient examination expense etc. for the treatment of flu, about 5,000,000,000 dollars will be lost every year.At U.S.'s common cold that once cost is the most expensive, that is exactly evening on February 7th, 1969, and occur in U.S. Kennedy launching site, rocket launching enters countdown, and conning-tower sends suddenly the order stopping launching.Originally at No. 9, the Apollo Personnel investigation Program being about to lift-off ' ' in spacecraft, all there is nasal obstruction, watery nasal discharge, pharyngalgia, the typical cold symptoms such as tired in 3 spacemans.For this reason, NASA is in a dilemma, finally have to recuperate through isolation by very reluctantly extension transmitting 03 spaceman, returns to one's perfect health after 1 week, again climbed up No. 9, Apollo Personnel investigation Program March 3 the same year " spacecraft.And current common cold, but cause the loss of 5,000,000,000 dollars to NASA, the most expensive flu of cost in history that Here it is.Up to now, flu is still a practical problem of the puzzlement U.S. common people., as Britain, Holland etc., also there is similar statistics report in other countries.

Pass through clinical observation, the present invention obviously can improve heating weight, distending pain in the head, has antiperspirant, red swelling and pain of throat, cough, expectorant are sticky or yellow, the symptoms such as yellow thick nasal discharge, thirst and liking drink, the micro-Huang of white and thin fur of having a stuffy nose, total effective rate reaches 90%, and does not find any obvious untoward reaction, and clinical effectiveness is satisfied.At present, clinically to evident in efficacy, safety good, Chinese medicine preparation easy to use still for be badly in need of.Therefore, exploitation of the present invention is expected to provide a safety, ideal Chinese medicine preparation effective, cheap, easy to use for clinical, is expected to obtain good economical, societal benefits after applying.

Summary of the invention

The invention belongs to the Chinese medicine preparation for the treatment of anemopyretic cold, it is characterized in that by relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, the Chinese prescription of heat-clearing and toxic substances removing forms, and comprises Flos Lonicerae 12 ~ 25%, Fructus Forsythiae 12 ~ 25%, Herba Menthae 2 ~ 13%, Herba Schizonepetae 7 ~ 16%, Fructus Arctii 10 ~ 19%, Radix Platycodonis 6 ~ 17%, Folium Bambusae 10 ~ 19%, Radix Glycyrrhizae 5 ~ 14%.Technical scheme of the present invention is: extract taste Chinese medicine each in the present invention, extracting solution concentrating under reduced pressure becomes concentrated solution; After concentrated solution is dried to extract dry powder by distinct methods, by adding different auxiliary material respectively, can be made into the solid preparations such as granule, capsule, tablet; Also can will add appropriate distilled water in concentrated solution, water precipitating adds adjuvant and the liquid preparation such as oral liquid and syrup made by antiseptic after filtering.The different auxiliary material added in different dosage form of the present invention, does not affect clinical effectiveness of the present invention, and these adjuvants comprise starch, microcrystalline Cellulose, magnesium stearate, dextrin, lactose, sucrose, antiseptic etc.Therefore the present invention can meet heating weight, distending pain in the head, have antiperspirant, red swelling and pain of throat, cough, expectorant glue or yellow, have a stuffy nose yellow thick nasal discharge, thirst and liking drink, the micro-yellow patient of white and thin fur to the requirement of different dosage form.

The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of anemopyretic cold.The Pharmacodynamic test of active extract result of this preparation shows: this preparation obviously can improve heating weight, distending pain in the head, has antiperspirant, red swelling and pain of throat, cough, expectorant are sticky or yellow, have a stuffy nose yellow thick nasal discharge, thirst and liking drink, the micro-Huang of white and thin fur.Acute toxicity test of the present invention and long term toxicity test result show to have no overt toxicity reaction.Clinically by Granules in Treating nasal obstruction yellow thick nasal discharge patient 20 example of the present invention, basic recovery 3 example, accounts for 15.00%; Remarkable recovery 14 example, accounts for 70.00%, total effective rate 85.00%.Tcm symptom improves total effective rate: heating is heavily 82.86 %, nasal obstruction yellow thick nasal discharge is 90.00%, red swelling and pain of throat is 84.36 %, expectorant is sticky or Huang is 84.6%, cough is 67.78 %, thirst and liking drink is 75.00 %, the micro-Huang of white and thin fur is 91.97 %.Illustrate that the present invention obviously can improve nasal obstruction yellow thick nasal discharge symptom, especially heating weight, distending pain in the head, red swelling and pain of throat, expectorant are glued or the improvement of the symptom such as Huang, the micro-Huang of white and thin fur obvious.Also observe the impact of granule of the present invention on safety indexes such as hematuria routine, Liver and kidney function in clinical trial process simultaneously, find Non Apparent Abnormality change before and after treatment.Clinical taking in process has not also reported gastrointestinal tract and other untoward reaction, illustrates that the present invention takes safety.Prescription of the present invention, on the basis of above-mentioned five kinds of Chinese medicine, also can add other and have the Chinese medicine protecting effect in harmonization of the stomach.Using method of the present invention: oral, every day three times, each 1 one 2 bags of granules (or 3 one 6 capsules, or 3-6 tablets of tablets, or 1-2 oral liquids or 10-20 ml syrup).It within 30 days, is a course for the treatment of.

embodiment 1:

Flos Lonicerae, Fructus Forsythiae, Herba Menthae, Herba Schizonepetae, Fructus Arctii, Radix Platycodonis, Folium Bambusae, Radix Glycyrrhizae powder are broken into coarse powder, decoct with water three times, collecting decoction, filter, filtrate is condensed into the concentrated solution that relative density is 1.20-1.22, continues to be condensed into thick paste, differently can do bath, pulverize, sieve, be the dry medicated powder of extraction of the present invention;

embodiment 2:

Flos Lonicerae, Fructus Forsythiae, Herba Menthae, Herba Schizonepetae, Fructus Arctii, Radix Platycodonis, Folium Bambusae, Radix Glycyrrhizae powder are broken into coarse powder, decoct with water three times, collecting decoction, filter, filtrate is condensed into the concentrated solution that relative density is 1.20-1.22, continues to be condensed into thick paste, is extraction medicinal liquid of the present invention;

embodiment 3: tablet

Adding starch, dextrin, magnesium stearate mixing by extracting in above-described embodiment in dry medicated powder, granulating, drying, sieve, be pressed into 1000, be tablet of the present invention.

embodiment 4: capsule

Adding starch, dextrin by extracting in above-described embodiment in dry medicated powder, mixing, granulate, sieving, fill 1000 capsules, be capsule of the present invention. embodiment 5: granuleadding dextrin, microcrystalline Cellulose, magnesium stearate, lactose, sucrose by extracting in above-described embodiment in dry medicated powder, granulation, granulate, to sieve, make granule, granule of the present invention. embodiment 6: oral liquidadd 400ml distilled water by extracting in above-described embodiment in medicinal liquid, sterilization, fill, makes 1000ml oral liquid, oral liquid of the present invention.

There is document announcement, in the U.S., 3,000,000,000 workaday labor efficiencies approximately will be caused every year to decline because catching a cold; In American students, there is the sick leave of 600,000,000 days because of flu; In working clan, then about to lose 500,000,000 working hours, add the tablet, cough syrup, collunarium liquid medicine, patient examination expense etc. for the treatment of flu, about 5,000,000,000 dollars will be lost every year.At U.S.'s common cold that once cost is the most expensive, that is exactly evening on February 7th, 1969, and occur in U.S. Kennedy launching site, rocket launching enters countdown, and conning-tower sends suddenly the order stopping launching.Originally at No. 9, the Apollo Personnel investigation Program being about to lift-off ' ' in spacecraft, all there is nasal obstruction, watery nasal discharge, pharyngalgia, the typical cold symptoms such as tired in 3 spacemans.For this reason, NASA is in a dilemma, finally have to recuperate through isolation by very reluctantly extension transmitting 03 spaceman, returns to one's perfect health after 1 week, again climbed up No. 9, Apollo Personnel investigation Program March 3 the same year " spacecraft.And current common cold, but cause the loss of 5,000,000,000 dollars to NASA, the most expensive flu of cost in history that Here it is.Up to now, flu is still a practical problem of the puzzlement U.S. common people., as Britain, Holland etc., also there is similar statistics report in other countries.

More than fact proved, the harm of flu is never negligible.Especially to specific groups such as old people, infant and anemia of pregnant woman, seem particular importance.So, suffers from the Middle Age and Aged Patients of pneumonopathy, nephropathy, apoplexy, heart disease, diabetes etc., once trouble common cold, also must treat in time, in case aggravation on August 20th, 2004 " Yangzi Evening " report, 4 years old youngest daughter does not treat in time because of once little flu, obtains severe myocarditis, doctors have to " pacemaker ' ' rescue her baby, this is that typical case's flu loses govern-education instruction.The present head of a family thinks little of child's flu, thus the thing delaying child's state of an illness happens occasionally.Child's resistance is poor, and repeated cold does not produce antibody again, and as treated thoroughly not in time, virus probably invades heart, and involves cardiac muscle and suffer from myocarditis.The ready-to-be mother of period of pregnancy should pay much attention to common cold and influenza, and under physician guidance, cures flu in time, exactly, and this has the meaning of particular importance to prenatal and postnatal care.

Therefore development of the present invention is faced with wide market, wherein contains great social benefit and huge economic benefit.

Claims (2)

1. be used for the treatment of a Chinese medicine preparation for anemopyretic cold, it is characterized in that it is made up of the raw material comprising following dosage proportioning: Flos Lonicerae 12 ~ 25%, Fructus Forsythiae 12 ~ 25%, Herba Menthae 2 ~ 13%, Herba Schizonepetae 7 ~ 16%, Fructus Arctii 10 ~ 19%, Radix Platycodonis 6 ~ 17%, Folium Bambusae 10 ~ 19%, Radix Glycyrrhizae 5 ~ 14%.

2. the preparation method of the Chinese medicine preparation for the treatment of anemopyretic cold according to claim 1, it is characterized in that the technological process of described preparation is: Flos Lonicerae, Fructus Forsythiae, Herba Menthae, Herba Schizonepetae, Fructus Arctii, Radix Platycodonis, Folium Bambusae, Radix Glycyrrhizae powder are broken into coarse powder, decoct with water three times, collecting decoction, filter, filtrate is condensed into the concentrated solution that relative density is 1.20-1.22, continue to be condensed into thick paste, differently can do bath, pulverize, sieve, be the dry medicated powder of extraction of the present invention; By adding starch, dextrin, microcrystalline Cellulose, magnesium stearate, lactose, sucrose, xanthan gum adjuvant, make granule, capsule, tablet.