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CN104207957A - Fibroin care solution with functions of contracting genitals and whitening, and preparation method thereof - Google Patents

Fibroin care solution with functions of contracting genitals and whitening, and preparation method thereof Download PDF

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Publication number
CN104207957A
CN104207957A CN201410474366.2A CN201410474366A CN104207957A CN 104207957 A CN104207957 A CN 104207957A CN 201410474366 A CN201410474366 A CN 201410474366A CN 104207957 A CN104207957 A CN 104207957A
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fibroin
add
extracting solution
carboxymethyl cellulose
sodium carboxymethyl
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CN201410474366.2A
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CN104207957B (en
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牛锐
万谦
齐胜超
彭玮
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SHENZHEN GANGPINYIJIA INDUSTRIAL Co Ltd
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SHENZHEN GANGPINYIJIA INDUSTRIAL Co Ltd
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Abstract

The invention discloses a fibroin care solution with functions of contracting genitals and whitening, and relates to the field of a disposable hygiene product. The fibroin care solution mainly comprises the following components by weight percent: 0.05-3% of fibroin, 0.1-5% of tightening agent, 0.1-10% of hydrolyzed elastic collagen, 0.2-1% of royal jelly and deionized water. The fibroin care solution can solve the problem that the skin of the private part of a woman is flabby based on the principle of skin aging, and is high in whitening effect due to the synergistic effect of all whitening components; the inhibiting effect for common pathogenic bacteria of plant extract is utilized, so that the potential hazard for the private part of the woman caused by a chemical disinfectant can be reduced, and the drug resistance of the bacteria can be avoided; a mild foaming agent is fed into the fibroin care solution, so that the foam type care solution is prepared; compared with the liquid care solution, the foam type care solution is more convenient to use.

Description

A kind of fibroin conditioning liquid with koro whitening function and preparation method thereof
Technical field
The present invention relates to Disposable Sanitary Accessory field, particularly a kind of conditioning liquid being exclusively used in women's privates.
Background technology
Feminine care solution is Precerving liquid conventional in a kind of daily life, and primary efficacy is to regulate the pH value of vaginal environment, clean and sterilization, the effect of some Feminine care solution also containing " beauty treatment ".The environment of vagina is often subject to the metabolite of host, the product of antibacterial itself and extrinsic factor (sexual intercourse, flushing and other interference) and unstable.Vaginal microbial flora is very complicated, and except protozoon, fungus, still comprise a lot of aerobe and anaerobe, these microorganisms can be divided into commensalism and pathologic, all grows in a common environment, has antagonism between each microorganism; Another factor affecting its growth is hydrogen ion concentration, when pH3.8 ~ 4.2, be conducive to the breeding of commensalism bacterium, especially lactobacillus, this is the main bacteria seed in healthy vagina, density in vaginal secretion can reach 105 ~ 108ml, after vagina is by infected by microbes, if lactobacillus is preponderated, still pH3.8 ~ 4.2 can be maintained, then can not cause a disease, and lactobacillus can also produce H202, vagina self-cleaning and infection can be maintained.Other are as common in vagina lower end in enterobacteria etc., restrict each other between vaginal microbial flora at ordinary times, pathological bacteria can not be acted on to some extent, do not produce symptom, if this balance is destroyed, condition each other event resolves, hydrogen ion concentration declines, lactobacillus is lost ground, and bacterium is bred pathology, just produces symptom.
At present, the conditioning liquid of a variety of women's privates on market, they generally all have clean women's privates, dispel privates abnormal flavour, prevent and treat the effects such as bacteriological infection.But these washing liquids adopt Organic substance as sterilization bacteriostat mostly, if life-time service, antibacterial easily produces drug resistance.The conditioning liquid of women's privates on the market generally all only has above-mentioned effect, some women is because the factors such as sexual intercourse, childbirth or endocrine disturbance easily cause the bad phenomenon such as women's privates skin blackout, privates skin aging and elasticity are not enough, these situations are not only bad for healthy, but also likely cause life quality to decline, even affect family harmony.Therefore develop a not only have clean, antibacterial, eliminate the unusual smell, can also shrink vagina, whitening women privates skin conditioning liquid necessary.
The lax reason of women's privates aging: the collagen protein 1, in skin corium along with the age increase and run off 2, fertility, sexual life cause elastic fibers break, 3, the estrogen decrease of ovarian secretion.
Number of patent application 201310302441 discloses a kind of conditioning liquid being exclusively used in women's privates, employing nanometer silver solution, watermiscible vitamin E, Radix Glycyrrhizae extract, fibroin peptide, procyanidin, water solublity bisabolol, MEIGUI CHUNLU, La-SOD, sodium carboxymethyl cellulose, 1,2-PD, glycerol and deionized water etc. are composite to be formed.Its conditioning liquid can clean women's privates, dispel privates abnormal flavour, also has the functions such as whitening privates skin, delay skin aging and increase privates skin elasticity.But there is following shortcoming in the conditioning liquid of this invention: 1, nanometer silver is toxic, energy is weakened line mitochondria function obviously, increase membrane permeation, damaging cells film, causes necrocytosis, and, nano silver particles can enter human body, to reproductive system have potential hazard (Xue Yuying, Tang Meng. nano-silver biological effect study progress [J]. Southeast China University's journal (natural science edition) 2009.11,39 (6), 1315-1320); 2, bactericidal range is comparatively wide, and sterilizing ability is comparatively strong, may kill intravaginal probiotics, as lactobacillus; 3, just rely on moisturizing, antioxidation two is used for increase privates skin elasticity, does not realize compacting of vagina from solving the basic reason these 2 that ovarian secretion estrogen reduces and women's privates relaxes.
Summary of the invention
For the problems referred to above, the invention provides a kind of fibroin conditioning liquid with koro whitening function and preparation method thereof, concrete scheme is as follows:
There is a fibroin conditioning liquid for koro whitening function, comprise following weight percent composition: fibroin 0.05%-3%, compact agent 0.1%-5%.
Described agent of compacting is one or more in dipalmitoyl hydroxyproline, Herba Centellae extract, Sargassum peptide, and the present invention is preferably dipalmitoyl hydroxyproline.
Further, the described fibroin conditioning liquid with koro whitening function, also comprises following weight percent composition: hydrolyzed elastin collagen protein 0.1%-10%, Lac regis apis 0.2%-1%.
Further, the described fibroin conditioning liquid with koro whitening function, also comprise following weight percent composition: Fructus Schisandrae Sphenantherae extracting solution 0.1%-5%, Radix Glycyrrhizae extract 0.1%-3%, Mel extracting solution 0.1%-0.5%, D-lactic acid 0.01%-0.1%, phytic acid 0.05%-0.5%, water-soluble α-bisabolol 0.1%-0.8%, alkyl androstanediol 1%-5%, sodium carboxymethyl cellulose 0.2%-0.8%, Basil Essential 0.01%-0.04%, orange blossom quintessence oil 0.01%-0.04%, solubilizing agent 0.05%-0.3%, surplus is deionized water.
Preferably, the molecular weight of described hydrolyzed elastin collagen protein is less than 500 dalton.
Preferably, described Fructus Schisandrae Sphenantherae extracting solution solid content is 3%-10%.
Preferably, described Radix Glycyrrhizae extract solid content is 3%-10%.
The extracting method of described Mel extracting solution: add the deionized water that 10 times of volumes are cooled to about 50 DEG C after the high temperature sterilize of Mel in reaction pot, slowly add Mel in reaction pot, and constantly stir; Material temperature controlling in reaction pot is added after 50 ± 3 DEG C 0.05 times amount in the protease of Mel, react 4 hours; Reaction terminates rear stirring and is warming up to 100 DEG C of enzyme denaturing 20 minutes, after being then cooled to 50-60 DEG C, filters with 100 orders; Filtrate is put into cold room freezing 24 hours, then thaw, filter with 100 orders; After filtrate high temperature sterilize, essence is filtered and be get final product.
The extracting method of described Fructus Schisandrae Sphenantherae extracting solution: (1) extracts: the drinking water adding 10 times of weight of being weighed by Fructus Schisandrae Sphenantherae soaks 1 hour, and heat and boil 2 hours, 100 mesh sieves are crossed in discharging; The drinking water adding 8 times amount is again heated and is boiled 1.5 hours, and 100 mesh sieves are crossed in discharging; Merge the 1 times weight of concentration of liquid medicine to Fructus Schisandrae Sphenantherae; (2) alcohol process: concentrated solution add 1.2 times of volumes ethanol stir precipitation, static, filter, reclaim ethanol, add purified water precipitation, leave standstill, 100 orders filter; (3) prepare: become by drug solution preparing solid content to be 3.0-10%, sterilizing, refilters and get final product.
The extracting method of described Radix Glycyrrhizae extract: (1) extracts: drinking water Radix Glycyrrhizae being added 10 times of weight soaks 1 hour, heats and boils 2 hours, and 100 mesh sieves are crossed in discharging; The drinking water adding 8 times amount is again heated and is boiled 1.5 hours, and 100 mesh sieves are crossed in discharging; Merge the 1 times weight of concentration of liquid medicine to Radix Glycyrrhizae; (2) alcohol process: concentrated solution add 1.2 times of volumes ethanol stir precipitation, static, filter, reclaim ethanol, add purified water precipitation, leave standstill, 100 orders filter; (3) prepare: drug solution preparing is become solid content 3.0-10%, sterilizing, refilter and get final product.
The above-mentioned preparation method with the fibroin conditioning liquid of koro whitening function, comprises the following steps:
1), by sodium carboxymethyl cellulose add in deionized water, heated and stirred is until sodium carboxymethyl cellulose dissolves completely;
2), by step 1) solution be cooled to 45 DEG C, add alkyl androstanediol, phytic acid, water-soluble α-bisabolol, fibroin, hydrolyzed elastin collagen protein, Fructus Schisandrae Sphenantherae extracting solution, Radix Glycyrrhizae extract, Lac regis apis, Mel extracting solution, solubilizing agent, Basil Essential, orange blossom quintessence oil, dipalmitoyl hydroxyproline be uniformly mixed;
3), in step 2) solution add D-lactic acid, regulate pH value of solution 3.8-4.2, preferably, regulate pH value of solution to 4.0.
This formula, except adding the fibroin also had in background technology, also added the composition that dipalmitoyl hydroxyproline, hydrolyzed elastin collagen protein, Lac regis apis, Basil Essential, orange blossom quintessence oil etc. sterilize and improve women's privates skin aging.
The efficacy effect of each component of the present invention is as follows:
Fibroin: (1) deep layer whitening, gos deep into skin bottom, fundamentally skin whitening and having no side effect; (2) long-acting moisturizing, nature moisturizing factor decuples conventional plant or chemical wetting agent, continues efficiently to keep the skin wet to skin; (3) nourish conditioning, penetration is strong, for skin provides required nutrient, promotes cellular metabolism, improves skin quality; (4) defying age, energy activating skin cell, improves microcirculation, defying age; (5) antioxidation, effectively resists external contamination, keeps skin pH balance, strengthens skin immunization power.
Dipalmitoyl hydroxyproline: (1) stimulates collagen fiber to reset; (2) elastin laminin is protected to destroy from enzyme; (3) scavenging free radicals, oxidation resistance is better than vitamin E.
Hydrolyzed elastin collagen protein: (1) promotes cell differentiation, propagation, promotes collagen and elastic cell's synthesis, strengthens skin elasticity; (2) nourishes rough skin, keeps cutin moisture, and moisturizing and reparation skin, strengthen skin elasticity; (3) trophism is good, skin care, prevents and delay skin aging, reappears skin gloss.
Lac regis apis: (1), containing trace oestrogen, makes up the deficiency of female estrogen secretion; (2) containing the abundant various active composition useful in the mankind, 2/3rds of protein in Lac regis apis is albumin, 1/3rd is globulin, consistent with human serum, Lac regis apis is also containing the natural organic acids 10-HAD (10-HDA) existed only in wherein, and 10-HDA has enhancing human body immunity function; (3) function of tissue regeneration is promoted, antimicrobial antiphlogistic function and the endocrine function of promotion.
Fructus Schisandrae Sphenantherae extracting solution: (1) bacteriostasis, when pH≤4, has good inhibitory action to staphylococcus aureus, Salmonella etc.; (2) antioxidation; (3) effect of skin-whitening is had.
Radix Glycyrrhizae extract: the activity of restraint of tyrosinase, reduces melanic generation, skin whitening.
Mel extracting solution: maintenance skin care, stablizes Lac regis apis.
D-lactic acid: regulate pH, maintains the acid-base balance of vaginal environment, suppresses noxious bacteria, can not suppress the probiotics of lactobacillus and so on.
Phytic acid: chelating ion, regulates pH.
Water-soluble α-bisabolol: reduce the zest that in formula, other raw materials produce skin, prevent allergy, protection sensitive skin.
Alkyl androstanediol: gentle foaming agent.
Sodium carboxymethyl cellulose: the viscosity regulating product.
Basil Essential: perfumery also improves slack and undisciplined, aging skin, stimulates estrogen secretion, improves menstruation.
Orange blossom quintessence oil: perfumery, and be rich in multiple whitening composition, penetrating power is 70 times of common skin care ingredient, can go deep into skin basal layer, decomposes melanin, strengthens cell viability, helps cell regeneration, increases skin elasticity; Also be effective estrualization agent, contribute to the problem of improvement aspect.
Solubilizing agent: Basil Essential and orange blossom quintessence oil are dissolved in water.
The present invention can solve the problem of women's privates cutis laxa from the principle of skin aging, these have the raw material of whitening function not only used fibroin and Radix Glycyrrhizae extract, also extremely strong containing penetration, skin basal layer can be goed deep into, decompose melanic orange blossom quintessence oil, three kinds of whitening composition synergism, whitening effect is stronger.Utilize this natural component of Fructus Schisandrae Sphenantherae extract to the inhibitory action of common pathogen, decrease the potential hazard that chemical bactericide (as triclosan, hibitane, nanometer silver etc.) brings women's privates, avoid antibacterial to produce drug resistance simultaneously.
With the addition of gentle foaming agent alkyl androstanediol, be configured to foam conditioning liquid, compare liquid use more convenient, and, the harmful bacteria of vaginal environment, if staphylococcus aureus, escherichia coli, Candida albicans are all the antibacterial and the fungus that need oxygen, and probiotics, as lactobacillus, it is anaerobe, the benefit of foam conditioning liquid is exactly by antibacterial and fungus and air insulated, thus only can suppress harmful bacteria, and does not suppress probiotics.
In order to verify that the present invention does not suppress the effect of probiotics to suppressing harmful bacteria, conditioning liquid of the present invention is done microorganism bacteriostatic test by inventor, and examination criteria is with reference to " GB15979-2002 Disposable Sanitary Accessory sanitary standard ".
The interpolation concentration of lactobacillus is 107cfu/ml, and detection method, with reference to " inspection of GB4789.35-2010 food microbiological examination lactobacillus ", requires that lactobacillus concentration is constant.
Result of the test
After sterilization terminates, detect each test group bacterium colony concentration, result is as shown in table 1:
Table 1
Strain Bacteriostasis rate requirement Testing result Evaluate
Total number of bacterial colonies ≤200cfu/ml <10cfu/ml Qualified
Coliform Must not detect Do not detect Qualified
Pathogenic bacterium Must not detect Do not detect Qualified
Fungus colony sum ≤100cfu/ml <10cfu/ml Qualified
Lactobacillus Concentration is constant 107cfu/ml Do not suppress lactobacillus
Can find out from the statistical result of table 1, sample is all very good to the fungistatic effect of three kinds of vaginal pathogenic, does not have inhibitory action for probiotics lactobacillus.
In order to verify koro of the present invention, whitening effect, 30 volunteers are organized to try out, once a day, each use amount 1ml, three months cycles on probation, after end, volunteer's questionnaire survey is filled in the degree easy to use of product, koro effect, whitening effect, cleaning effect, by well, generally, to no effect grade, general above for passing through, statistics effective percentage, is greater than 75% for qualified, wherein, the verification method of whitening effect is: allow volunteer take pictures to privates before use, takes pictures after three months again, the change of contrast site color.Result is as shown in table 2:
Table 2
Can find out from the statistical result of table 2, inventive samples is easy to use, and well can clean privates, koro whitening effect is remarkable.
In order to react trial state of the present invention further, from 30 volunteers, selecting several volunteers, verifying effect of the present invention (be and directly quote) according to their Detailed Feedback situation, adding up as shown in table 3:
Table 3
Detailed description of the invention
In order to more fully understand technology contents of the present invention, below in conjunction with specific embodiment technical scheme of the present invention being introduced further and illustrating.
The conditioning liquid prepared in following examples, each component percentages is weight percentage, the content of deionized water be other component percentages and surplus.
In following examples, the molecular weight of hydrolyzed elastin collagen protein is less than 500 dalton; Fructus Schisandrae Sphenantherae extracting solution is that solid content is 3% with deionized water extraction; Radix Glycyrrhizae extract is that solid content is 3% with deionized water extraction.
Embodiment 1:
Add in deionized water by the sodium carboxymethyl cellulose of 0.2%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 1%, the phytic acid of 0.05%, water-soluble α-bisabolol, the fibroin of 0.05%, hydrolyzed elastin collagen protein, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the Lac regis apis of 0.2%, Mel extracting solution, the solubilizing agent of 0.05%, Basil Essential, the orange blossom quintessence oil of 0.01%, the dipalmitoyl hydroxyproline of 0.1% of 0.01% of 0.1% of 0.1% of 0.1% of 0.1% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 2:
Add in deionized water by the sodium carboxymethyl cellulose of 0.4%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 1%, the phytic acid of 0.05%, water-soluble α-bisabolol, the fibroin of 0.05%, hydrolyzed elastin collagen protein, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the Lac regis apis of 0.2%, Mel extracting solution, the solubilizing agent of 0.05%, Basil Essential, the orange blossom quintessence oil of 0.01%, the dipalmitoyl hydroxyproline of 0.1% of 0.01% of 0.1% of 0.1% of 0.1% of 0.1% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 3:
Add in deionized water by the sodium carboxymethyl cellulose of 0.6%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 1%, the phytic acid of 0.05%, water-soluble α-bisabolol, the fibroin of 0.05%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 0.1% of 0.1% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 4:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 1%, the phytic acid of 0.05%, water-soluble α-bisabolol, the fibroin of 0.05%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 0.1% of 0.1% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 5:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 3%, the phytic acid of 0.05%, water-soluble α-bisabolol, the fibroin of 0.05%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 0.1% of 0.1% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 6:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.05%, water-soluble α-bisabolol, the fibroin of 0.05%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 0.1% of 0.1% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 7:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 0.1% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 8:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.5%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 0.1% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 9:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 0.1% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 10:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 1.5%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 0.1% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 11:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 2%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 0.1% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 12:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 3%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 0.1% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 13:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 1% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 14:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 15:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 4% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 16:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 6% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 17:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 8% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 18:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.2%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 10% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 19:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.4%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 20:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.6%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 21:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.7%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 22:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.8%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 23:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 1%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.6%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 24:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 2%, hydrolyzed elastin collagen protein, the Lac regis apis of 0.8%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 25:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.1% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 26:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.2% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 25:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.3% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 26:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.4% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 27:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 28:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 0.5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 29:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 30:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 31:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 2%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 32:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 2.5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 33:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 3%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 34:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.1% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 35:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 0.5% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 36:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 1% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 37:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 2% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 38:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 3% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 39:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 0.5%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 3% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 40:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 3% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 41:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 1.5%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 3% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 42:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 2%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 3% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 43:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 2.5%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 3% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 44:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 3%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 3% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 45:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 3.5%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 3% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 46:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 4%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 3% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 47:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 4.5%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 3% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 48:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.1%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 5%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 5%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.05% of 3% of 0.5% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 49:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.3%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 2%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.1% of 0.5% of 0.2% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 50:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.3%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 1%, Radix Glycyrrhizae extract, the dipalmitoyl hydroxyproline of 2%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.3% of 0.5% of 0.2% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 51:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.3%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 1%, Radix Glycyrrhizae extract, the Herba Centellae extract of 2%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.3% of 0.5% of 0.2% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 52:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, the phytic acid of 0.1%, water-soluble α-bisabolol, the fibroin of 0.3%, hydrolyzed elastin collagen protein, the Lac regis apis of 1%, Mel extracting solution, the Fructus Schisandrae Sphenantherae extracting solution of 1%, Radix Glycyrrhizae extract, the Sargassum peptide of 2%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.3% of 0.5% of 0.2% of 2% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
Embodiment 53:
Add in deionized water by the sodium carboxymethyl cellulose of 0.8%, heated and stirred is until sodium carboxymethyl cellulose dissolves completely; Be cooled to 45 DEG C, add the alkyl androstanediol of 5%, 0.1% phytic acid, the water-soluble α-bisabolol of 0.3%, fibroin, the hydrolyzed elastin collagen protein of 2%, Lac regis apis, the Mel extracting solution of 0.2%, Fructus Schisandrae Sphenantherae extracting solution, the Radix Glycyrrhizae extract of 0.5%, dipalmitoyl hydroxyproline, the Sargassum peptide of 1%, solubilizing agent, the Basil Essential of 0.01%, the orange blossom quintessence oil of 0.01% of 0.3% of 1% of 1% of 1% of 0.3% be uniformly mixed; The D-lactic acid adding 0.04% regulates pH value of solution, and the pH measuring gained conditioning liquid is 4.0.
The above only further illustrates technology contents of the present invention with embodiment, so that reader is easier to understand, but does not represent embodiments of the present invention and is only limitted to this, and any technology done according to the present invention extends or recreation, all by protection of the present invention.

Claims (9)

1. there is a fibroin conditioning liquid for koro whitening function, it is characterized in that, comprise the agent of compacting of the fibroin of percentage by weight 0.05%-3%, 0.1%-5%.
2. the fibroin conditioning liquid with koro whitening function according to claim 1, is characterized in that, described agent of compacting is one or more in dipalmitoyl hydroxyproline, Herba Centellae extract, Sargassum peptide.
3. the fibroin conditioning liquid with koro whitening function according to claim 2, is characterized in that, also comprise following weight percent composition: hydrolyzed elastin collagen protein 0.1%-10%, Lac regis apis 0.2%-1%.
4. the fibroin conditioning liquid with koro whitening function according to claim 3, is characterized in that: the molecular weight of described hydrolyzed elastin collagen protein is less than 500 dalton.
5. the fibroin conditioning liquid with koro whitening function according to claim 3, it is characterized in that, also comprise following weight percent composition: Fructus Schisandrae Sphenantherae extracting solution 0.1%-5%, Radix Glycyrrhizae extract 0.1%-3%, Mel extracting solution 0.1%-0.5%, D-lactic acid 0.01%-0.1%, phytic acid 0.05%-0.5%, water-soluble α-bisabolol 0.1%-0.8%, alkyl androstanediol 1%-5%, sodium carboxymethyl cellulose 0.2%-0.8%, Basil Essential 0.01%-0.04%, orange blossom quintessence oil 0.01%-0.04%, solubilizing agent 0.05%-0.3%, surplus is deionized water.
6. the fibroin conditioning liquid with koro whitening function according to claim 5, is characterized in that: described Fructus Schisandrae Sphenantherae extracting solution solid content is 3%-10%.
7. the fibroin conditioning liquid with koro whitening function according to claim 5, is characterized in that: described Radix Glycyrrhizae extract solid content is 3%-10%.
8. there is a preparation method for the fibroin conditioning liquid of koro whitening function as described in claim 1-7 any one, it is characterized in that, comprise the following steps:
1), by sodium carboxymethyl cellulose add in deionized water, heated and stirred is until sodium carboxymethyl cellulose dissolves completely;
2), by step 1) solution be cooled to 45 DEG C, add alkyl androstanediol, phytic acid, water-soluble α-bisabolol, fibroin, hydrolyzed elastin collagen protein, Fructus Schisandrae Sphenantherae extracting solution, Radix Glycyrrhizae extract, Lac regis apis, Mel extracting solution, solubilizing agent, Basil Essential, orange blossom quintessence oil, dipalmitoyl hydroxyproline be uniformly mixed;
3), in step 2) solution add D-lactic acid, regulate pH value of solution 3.8-4.2.
9. the preparation method with the fibroin conditioning liquid of koro whitening function according to claim 8, is characterized in that: described step 3) in, add D-lactic acid, regulate pH value of solution to 4.0.
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CN105012078A (en) * 2015-08-03 2015-11-04 彭艳燕 Postpartum convalescence sanitary towel
CN106166133A (en) * 2016-08-14 2016-11-30 湖南蜜蜂哥哥蜂业有限公司 A kind of Lac regis apis beautifying patch and preparation technology thereof
CN108144045A (en) * 2017-12-29 2018-06-12 广州绿人生物科技有限公司 A kind of biological agent for women and its application
CN108743780A (en) * 2018-08-23 2018-11-06 杭州元研细胞生物科技有限公司 A kind of vulva conditioning liquid and preparation method thereof containing plant extracts
CN111529414A (en) * 2020-06-18 2020-08-14 广东景兴健康护理实业股份有限公司 Silk fibroin skin beautifying care solution and preparation method thereof
CN114949351A (en) * 2022-06-10 2022-08-30 孙菲 Preparation method of filler for vaginal filling

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CN102988231A (en) * 2012-11-15 2013-03-27 隋丽梅 Feminine care solution and preparation method thereof
CN103356438A (en) * 2013-07-11 2013-10-23 深圳市宜丽环保科技有限公司 Special-purposed care solution for female private part

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CN1939518A (en) * 2006-10-12 2007-04-04 胡木明 Herbal curing liquid for female monthly period and daily use with vagina contraction, sterilizing and antipruritic functions
CN102988231A (en) * 2012-11-15 2013-03-27 隋丽梅 Feminine care solution and preparation method thereof
CN103356438A (en) * 2013-07-11 2013-10-23 深圳市宜丽环保科技有限公司 Special-purposed care solution for female private part

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Publication number Priority date Publication date Assignee Title
CN105012078A (en) * 2015-08-03 2015-11-04 彭艳燕 Postpartum convalescence sanitary towel
CN106166133A (en) * 2016-08-14 2016-11-30 湖南蜜蜂哥哥蜂业有限公司 A kind of Lac regis apis beautifying patch and preparation technology thereof
CN106166133B (en) * 2016-08-14 2019-05-17 湖南蜜蜂哥哥蜂业有限公司 A kind of royal jelly beautifying patch and its preparation process
CN108144045A (en) * 2017-12-29 2018-06-12 广州绿人生物科技有限公司 A kind of biological agent for women and its application
CN108743780A (en) * 2018-08-23 2018-11-06 杭州元研细胞生物科技有限公司 A kind of vulva conditioning liquid and preparation method thereof containing plant extracts
CN111529414A (en) * 2020-06-18 2020-08-14 广东景兴健康护理实业股份有限公司 Silk fibroin skin beautifying care solution and preparation method thereof
CN114949351A (en) * 2022-06-10 2022-08-30 孙菲 Preparation method of filler for vaginal filling

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