CN104206919B - A kind of feed for Roman laying hens containing D-ribose feed additive - Google Patents

Abstract

The invention relates to a Roman laying hen feed containing a D-ribose feed additive, which comprises the following main raw material components: corn, bean pulp, cooked millet, tomato seed meal, peanut skin, sunflower seeds, cooked egg yolk, sweet potato powder, calcium hydrogen phosphate, stone powder and salt, wherein the main raw materials are also added with microelement premix, a D-ribose additive and a traditional Chinese medicine additive, the D-ribose additive comprises D-ribose, bran, corn cob meal, medical stone and high calcium stone powder, and the traditional Chinese medicine additive comprises Chinese magnoliavine fruit, medicated leaven, baical skullcap root, indigowoad leaf, heartleaf houttuynia herb, red-rooted salvia root, Chinese angelica, finger citron, wild buckwheat rhizome, white paeony root and malt. By adjusting the formula of the staple food grain, and adding the D-ribose feed additive, the added premix trace elements and the traditional Chinese medicine additive into the staple food grain, the balance of microbial flora in animals is improved, and the proliferation activity of intestinal bifidobacteria is selectively promoted, so that the physique and the production performance of the Roman laying hens are improved.

Description

A kind of feed for Roman laying hens containing D-ribose feed additive

technical field

The invention relates to the technical field of feed for Roman laying hens, in particular to a feed for Roman laying hens containing D-ribose feed additive.

Background technique

Roman laying hens have the advantages of high egg production rate, high feed conversion rate, moderate egg weight, excellent egg quality, and hard shell. Roman laying hens have high production performance, peak egg production and long-lasting egg production after the peak. Roman laying hens have a very docile temperament, strong adaptability, strong disease resistance and easy management. However, Roman laying hens have a large demand for nutrients during the growth and development process, and have relatively high requirements for feed. During the breeding process of laying hens, the cost of feed accounts for about 70% of the cost. Existing feeds for Roman laying hens are generally heavy in protein and light in energy during the preparation process, and there are basically no components that can enhance chicken body skills and improve its disease resistance, resulting in low feed utilization and increased breeding costs. In addition, the unbalanced nutrition of chicken flocks leads to a decrease in egg production rate, short laying cycle, and slow metabolism, resulting in high incidence of chicken flocks. Therefore, according to the physiological characteristics of laying hens, the key to reducing the cost of breeding is to make the nutrition more balanced through scientific proportioning. At the same time, avoid adding some chemical anti-disease drugs in the feed, but add some traditional Chinese medicine ingredients without side effects and harm. , can improve the disease resistance and antibacterial ability of chickens, solve the problem of drug residues, and improve the quality of eggs.

D-ribose (D-ribose) is a natural aldopentose present in all living cells, its molecular formula is C ₅ H ₁₀ O ₅ , its relative molecular weight is 150.13, and its melting point is 86-87°C. Pure D-ribose is white crystalline powder, easy to absorb moisture, soluble in water, slightly soluble in ethanol, insoluble in ether, propiophenone and chloroform, etc. Due to the chiral carbon atom in the ribose structure, there are two types of optical isomerism: D-type and L-type, but in nature, it mainly exists in the state of D-type compound, that is, D-ribose. D-ribose is a component of biological genetic material mRNA, rRNA, 5sRNA and many other RNAs and many coenzymes. It is in a pivotal position in the metabolism of nucleosides, proteins, and fats. It has important physiological functions and broad application prospects. D-ribose, as a natural component present in all cells in organisms, is closely related to the formation of adenosine acid and the regeneration of adenosine triphosphate (ATP), and is one of the most basic energy sources for life metabolism. But before this application, there is no relevant research and report on the D-ribose additive being used in the feed of Roman laying hens.

Contents of the invention

The technical problem to be solved by the present invention is to aim at the deficiencies in the prior art, and provide a kind of feed for Roman laying hens containing D-ribose feed additive, by adjusting the staple food formula, and adding D-ribose feed additive, The premixed trace elements and traditional Chinese medicine additives can improve the balance of microbial flora in animals, selectively promote the proliferation of intestinal bifidobacteria, thereby improving the physique and production performance of Roman layer hens.

Solution of the present invention is realized by following technical measure:

A feed for Roman laying hens containing D-ribose feed additive is characterized in that the feed for Roman laying hens includes the following main raw material components: corn, soybean meal, boiled millet, tomato seed meal, peanut red coat, sunflower seed, boiled Cooked egg yolk, sweet potato powder, potato powder, calcium hydrogen phosphate, stone powder, salt, and trace element premix, D-ribose additive, and traditional Chinese medicine additive are also added to the above main raw materials.

The above-mentioned feed for Roman laying hens includes the following raw materials by weight: 30% to 45% of corn, 10% to 20% of soybean meal, 15% to 20% of cooked millet, 5% to 10% of tomato seed meal, 10%~15% of peanut red coat, 5%~10% of sunflower seed, 5%~10% of cooked egg yolk, 1%~5% of sweet potato powder, 1%~5% of potato powder, 1%~3 calcium hydrogen phosphate %, stone powder 1%~3%, salt 0.3%~0.8%, trace element premix 0.5%~2%, traditional Chinese medicine additive 1%~5%, D-ribose additive 50mg~500mg per kilogram of the above feed.

The trace element premix mentioned above contains vitamin A, vitamin D ₃ , vitamin E, vitamin K ₃ , riboflavin, pantothenic acid, niacin, biotin, vitamin B ₁₂ , manganese, iron, zinc, copper, iodine ,selenium.

The cost contained in the above-mentioned trace element premix contains vitamin A 5000～6000IU, vitamin D ₃ 500～700IU, vitamin E 30.0～40.0mg, vitamin K ₃ 2.0～3.0mg, vitamin B ₁₂ 90.0mg per kilogram of feed ～110.0ug, riboflavin 5.0～8.0mg, pantothenic acid 15.0～20.0mg, niacin 40.0～50.0mg, biotin 0.2～0.4mg, iron 230.0～250.0mg, zinc 110.0～130.0mg, copper 20.0～30.0mg, Manganese 170-190 mg, selenium 0.4-0.6 mg, iodine 0.20-0.40 mg.

The above-mentioned D-ribose additives include D-ribose, bran, corncob powder, medical stone, and high-calcium stone powder.

The ingredients in the above-mentioned D-ribose additive include by weight: 35%-45% of D-ribose, 25%-25% of bran, 8%-18% of corncob powder, 5%-15% of medical stone, High calcium stone powder 10% to 25%.

The dosage forms of the above-mentioned D-ribose additives can be made into tablets, capsules, granules, and oral liquids.

The nutrient level of the feed for Roman layer hens mentioned above is: crude protein 18.00%~22.00%, calcium 0.8%~1.00%, available phosphorus 0.30%~0.50%, lysine 0.7%~5.00%, methionine+cystine 0.70% to 4.00%.

The above-mentioned traditional Chinese medicine additives contain Schisandra chinensis, Divine Comedy, Scutellaria baicalensis, Daqingye, Houttuynia cordata, Salvia miltiorrhiza, Angelica, bergamot, golden buckwheat, white peony root, and malt, and the ingredients include: Schisandra 5% to 10% by weight , Divine Comedy 6%~13%, Scutellaria baicalensis 1%~5%, Daqingye 3%~8%, Houttuynia cordata 10%~20%, Salvia miltiorrhiza 5%~15%, Angelica 5%~10%, Bergamot 10% ~15%, golden buckwheat 10%~15%, white peony root 1%~5%, malt 10%~25%.

The beneficial technical effects of the present invention are: the feed for Roman laying hens described in the present invention can selectively promote the proliferation of intestinal flora, improve the balance of microbial flora in poultry, promote the reproduction of beneficial bacteria in the digestive tract of animals, inhibit the growth of harmful bacteria, reduce Incidence of other diseases, promotion of growth. No pollution, no toxic side effects, no residue, not only can prevent and resist diseases, improve feed utilization efficiency, but also greatly improve the production performance of poultry. Moreover, the raw and auxiliary materials are easy to obtain, and the preparation process is simple, which is beneficial to the expanded production.

D-ribose is a five-carbon sugar that exists in all living cells. It is an important component of genetic material nucleic acid in organisms. It is closely related to the formation of adenosine and the regeneration of ATP, and can enter the remedial synthesis pathway of ATP. , creates conditions for the rapid generation of ATP, is one of the most basic energy sources of life metabolism, plays a key role in the metabolism of the heart and skeletal muscle, can promote the recovery of local tissue ischemia and hypoxia, and supplement the energy in the Roman chicken , Relieve fatigue and shorten the recovery time after exercise.

detailed description

In order to clearly illustrate the technical features of the solution of the present invention, the present invention will be described below in conjunction with specific examples, but the examples are not intended to limit the present invention, and the scope of protection of the present invention is subject to the claims.

(1) Preparation of D-ribose additive

Example 1:

Every 100g of D-ribose feed additive contains: 45g of D-ribose, 15g of bran, 8g of corncob powder, 10g of medical stone, 22g of high-calcium stone powder. Said weight is evenly mixed to make D-ribose feed additive.

Embodiment 2:

Every 100g of D-ribose feed additive contains: 40g of D-ribose, 18g of bran, 15g of corncob powder, 10g of medical stone, 17g of high-calcium stone powder. Said weight is evenly mixed to make D-ribose feed additive.

Example 3:

Every 100g D-ribose feed additive contains: D-ribose 35g, bran 20g, corn cob powder 15g, medical stone: 15g, high calcium stone powder 15g. The above materials are pulverized in a pulverizer, passed through a 60-mesh sieve, and uniformly mixed according to the stated weight to make the D-ribose feed additive.

(2) Preparation of traditional Chinese medicine additives

Example 4:

Every 100g of Chinese medicine additives contains: Schisandra 5g, Divine Comedy 6g, Scutellaria baicalensis 5g, Daqingye 5g, Houttuynia cordata 15g, Salvia miltiorrhiza 10g, Angelica 6g, bergamot 10g, golden buckwheat 15g, white peony root 3g, malt 20g, the above materials in Pulverize in a pulverizer, pass through a 60-mesh sieve, and mix evenly according to the stated weight to make a traditional Chinese medicine feed additive.

Example 5:

Every 100g of traditional Chinese medicine additives contains: Schisandra 10g, Divine Comedy 10g, Scutellaria baicalensis 3g, Daqingye 5g, Houttuynia cordata 10g, Salvia miltiorrhiza 10g, angelica 8g, bergamot 10g, golden buckwheat 10g, white peony root 5g, malt 19g, the above materials in Pulverize in a pulverizer, pass through a 60-mesh sieve, and mix evenly according to the stated weight to make a traditional Chinese medicine feed additive.

Embodiment 6:

Every 100g of Chinese medicine additives contains: Schisandra 5g, Divine Comedy 6g, Scutellaria baicalensis 1g, Daqingye 3g, Houttuynia cordata 15g, Salvia miltiorrhiza 5g, Angelica 5g, bergamot 15g, golden buckwheat 15g, white peony root 5g, malt 25g, the above materials in Pulverize in a pulverizer, pass through a 60-mesh sieve, and mix evenly according to the stated weight to make a traditional Chinese medicine feed additive.

(3) Application of feed described in the present invention on Roman laying hens

1. Purpose of the experiment

512 1-day-old AA Roman laying hens were randomly divided into 4 groups, fed with 0, 100, 150, 200 mg D-ribose additive/kg basal ration and 0, 10, 20, 30 g of traditional Chinese medicine respectively in the basal diet Additives/kg basal rations were used to study the effects of D-ribose additives on production performance and serum-related biochemical indicators of Roman layer hens.

2. Experimental animals and experimental design

Select 512 AA Roman laying hens with an average weight of (46.3 ± 1.8) g at the age of 1 day, randomly divide them into 4 groups, each group has 8 replicates, and each replicate has 16 feathers, and they are fed with 4 kinds of diets: (1) Basic Diet (control group); (2) basal diet + 100 mgD-ribose additive/kg basal ration + 10g traditional Chinese medicine additive/kg basal ration; (3) basal ration + 150mgD-ribose additive/kg basal ration +20g traditional Chinese medicine additive/kg basic diet; (4) basic diet+200mgD-ribose additive/kg basic diet+30g traditional Chinese medicine additive/kg basic diet. The formula and nutritional level of the basic diet for the test are shown in Table 1, and the test material is powder.

Table 1 Basic diet formula and nutritional level

The metabolizable energy of the above diets were 12.56MJ/kg and 12.98 MJ/kg respectively.

Note: The trace element premix (per kilogram of feed) contains: vitamin A 5500IU, vitamin D ₃ 650IU, vitamin E 35mg, vitamin K ₃ 2.5mg, riboflavin 7.5mg, pantothenic acid 18.6mg, niacin 45.0mg, biotin 0.25 mg, vitamin B ₁₂ 100ug, manganese 180mg, iron 240mg, zinc 120mg, copper 25mg, iodine 0.3mg, selenium 0.5mg.

3. Feeding management

The test Roman layer hens were raised in the same chicken house, using stacked cages, automatic drinking and feeding, 24h continuous light, immunization procedures and other feeding and management were carried out as usual.

4. Sample collection

When Roman laying hens were 21 days old and 42 days old, 3 medium-sized cocks were randomly selected for each repetition and slaughtered, the blood was collected in a clean centrifuge tube, and after standing for a period of time, centrifuged in a low-temperature centrifuge at 3000 r/min After 15 min, the supernatant was collected and stored in a -20°C freezer for later use.

5. Index determination

(1) Production performance: Feed intake and number of dead pans were recorded daily, and Romain laying hens were weighed on an empty stomach on the 21d and 42d of the experiment. Calculate the average weight and feed-to-weight ratio.

(2) Serum biochemical indicators: Measured by an automatic biochemical analyzer, the kit used in the determination is provided by Nanjing Jiancheng Bioengineering Co., Ltd. Total protein (TP): colorimetric determination by biuret method; albumin (ALB): determination by bromocresol green colorimetric method; globulin (G) = total protein - albumin; albumin/globulin: ALB/GLO ; Triglyceride (TG) and total cholesterol (TC): Determination of GPO-PAP enzymatic method; Serum glucose (GLU): Determination of glucose oxidase method.

6. Statistical analysis of data

The experimental data was preliminarily processed with Excel, and SPSS 13 software was used for statistics, and one-way analysis of variance was used for significant difference test and multiple comparisons, and the results were expressed as mean ± standard error.

7. Results and analysis

(1) Effect of D-ribose on the production performance of Roman laying hens

Table 2 Effect of D-ribose additive on production performance of AA Roman laying hens

Note: Different lowercase letters after the data in the same column indicate significant differences (P<0.05).

It can be seen from Table 2 that, compared with the control group, the addition of D-ribose feed additive had no significant effect on the production performance (average body weight and feed-to-weight ratio) of Roman laying hens at each stage (P>0.05). Adding D-ribose increased the average body weight of 1-21-day-old Roman laying hens, and decreased the feed-to-weight ratio, but had no obvious effect on the later growth.

(2) Effect of D-ribose additives on serum biochemical indicators of Roman layer hens

Table 3 Effects of D-ribose on serum biochemical indicators of Roman layer hens

Note: Different lowercase letters after the data in the same column indicate significant differences (P<0.05).

As shown in Table 3, the addition of D-ribose feed additive had no significant effect on the early serum TP, ALB, G, ALB/GLO, TG and TC of Roman laying hens (P>0.05), but the serum TG and TC tended to decrease , in which TC in groups 2, 3, and 4 decreased by 7.25%, 8.39%, and 6.19% respectively; adding 150 mg/kg D-ribose in the early stage significantly reduced blood sugar levels (P<0.05).

Compared with the control group, there was no significant difference in G, ALB/GLO, TG and GLU in the late period of Roman laying hens in the D-ribose additive group (P>0.05), but TG in each test group had a tendency to decrease. , 4 groups decreased by 20.2%, 26.5%, 23.8% respectively; the TP of the 3rd group decreased significantly (P<0.05), and the TP of the 2nd and 4th groups tended to decrease, but did not reach a significant level (P>0.05); The ALB of the test groups decreased, among which the 3rd and 4th groups reached a significant level (P<0.05), and the TC of the 2nd, 3rd, and 4th groups decreased by 11.3%, 12.5%, and 10.9% respectively, and the 3rd group reached a significant level (P<0.05). level (P<0.05).

Claims (3)

1. A feed for Roman laying hens containing D-ribose feed additive, characterized in that the feed for Roman laying hens comprises the following raw materials by weight: 30% to 45% of corn, 10% to 20% of soybean meal, cooked 15% to 20% of millet, 5% to 10% of tomato seed meal, 10% to 15% of peanut red coat, 5% to 10% of sunflower seed, 5% to 10% of cooked egg yolk, 1% to 5% of sweet potato powder %, potato powder 1%~5%, calcium hydrogen phosphate 1%~3%, stone powder 1%~3%, salt 0.3%~0.8%, trace element premix 0.5%~2%, traditional Chinese medicine additives 1%~5% %, D-ribose additives are added at a rate of 50mg to 500mg per kilogram of the above-mentioned feed; The trace element premix contains 5000-6000 IU of vitamin A, 500-700 IU of vitamin _D3 , _30.0-40.0 mg of vitamin E, 2.0-3.0 mg of vitamin K3, _90.0-90.0 mg of vitamin B12 per kilogram of feed. 110.0ug, riboflavin 5.0-8.0mg, pantothenic acid 15.0-20.0mg, nicotinic acid 40.0-50.0mg, biotin 0.2-0.4mg, iron 230.0-250.0mg, zinc 110.0-130.0mg, copper 20.0-30.0mg, manganese 170~190mg, selenium 0.4~0.6mg, iodine 0.20~0.40mg; The D-ribose additive includes D-ribose, bran, corncob powder, medical stone, high-calcium stone powder, and the ingredients include: 35% to 45% of D-ribose, 25% to 25% of bran , corn cob powder 8% ~ 18%, medical stone 5% ~ 15%, high calcium stone powder 10% ~ 25%; The traditional Chinese medicine additive contains Schisandra chinensis, Divine Comedy, Scutellaria baicalensis, Daqingye, Houttuynia cordata, Salvia miltiorrhiza, Angelica sinensis, Bergamot, Golden buckwheat, Radix Paeoniae Alba, and malt. Divine Comedy 6%~13%, Scutellaria baicalensis 1%~5%, Daqingye 3%~8%, Houttuynia cordata 10%~20%, Salvia miltiorrhiza 5%~15%, Angelica 5%~10%, Bergamot 10%~ 15%, golden buckwheat 10%~15%, white peony root 1%~5%, malt 10%~25%. 2. A kind of Romanian laying hen feed containing D-ribose feed additive according to claim 1, is characterized in that: the dosage form that described D-ribose additive can be made is tablet, capsule, granule, oral liquid . 3. A kind of feed for Roman laying hens containing D-ribose feed additive according to claim 1, characterized in that the nutritional level of the feed for Roman laying hens is: crude protein 18.00%～22.00%, calcium 0.8%～1.00% , Available phosphorus 0.30% ~ 0.50%, lysine 0.7% ~ 5.00%, methionine + cystine 0.70% ~ 4.00%.