CN104187634A

CN104187634A - Total nutrient formula food for sarcopenia

Info

Publication number: CN104187634A
Application number: CN201410402199.0A
Authority: CN
Inventors: 胡安然
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-08-15
Filing date: 2014-08-15
Publication date: 2014-12-10

Abstract

The invention discloses total nutrient formula food, specific total nutrient formula food or non-total nutrient formula food for patients with sarcopenia. The formula, as required by Food for Special Medical Purposes (FSMP), is developed in combination with physical characteristics of patients with sarcopenia as well as current research results of Harvard University in the US on advanced physiology, medicine and pharmacology, nutriology, clinical application, and the like in accordance with an essential theory (based on principle of simultaneously regulating liver, spleen and kidney) of traditional Chinese medicine of'elimination for tonifying' and'balanced nourishing'. The finished product is prepared by mixing raw materials mainly including essence of extracts of various medicinal and edible traditional Chinese medicines, a plurality of probiotics and oligopeptide as well as auxiliary materials such as prebiotics, carbohydrate, amino acid, multiple vitamins and mineral substances. The food not only can be as a single nutrient source to meet nutritional requirements of patients with sarcopenia, but also has the effects of invigorating spleen-stomach and benefiting qi, promoting yang to lift qi sinking, nourishing liver and spleen, inducing resuscitation, strengthening bones and muscles, dispelling wind and unblocking the meridian, moistening and promoting skin regeneration, and enhancing immunity.

Description

The full nutrient formulation food of muscle decay syndrome

Technical field

The invention belongs to integration of drinking and medicinal herbs class formula and food technology field, specifically the Traditional Chinese Medicine marrow of " medicine among integration of drinking and medicinal herbs " is theoretical and " multiple probio " combines, and adds the full nutrient formulation food of muscle decay syndrome, specific full nutrient formulation food or the non-full nutrient formulation food made as auxiliary material taking small peptide, prebiotics, amino acid, carbohydrate, B B-complex, composite mineral matter.

Background technology

Muscle decay syndrome (Sarcopenia) is a kind of along with the age increases, reduce with skeletal muscle mass, muscle strength drops to the degeneration syndrome of principal character. and large quantity research shows, muscle decay syndrome has become an outstanding problem that has a strong impact on middle-aged and old normal lifves and self-care ability, in addition, also increase and suffer from diabetes, arthritis, osteoporosis is levied, the danger of the diseases such as heart disease, bring heavy financial burden to society and health delivery system, cause the reason of muscle decay a lot, and one of protein malnutrition hazards that to be it main, enter after the senescence phase, the ability of health synthetic protein reduces, catabolism strengthens, in addition the elderly's sense of taste, hyposphresia, tooth is bad, depressed grade causes senile poor appetite, digestive function goes down, protein utilization declines, also have part the elderly and get fat and suffer from cardiovascular and cerebrovascular disease because worry, adopt taking vegetarian diet as main diet, the quality and quantity that makes to take in protein is all poor, research is recently found, vitamin D deficiency easily causes muscle decay, and the elderly's outdoor activities are few, accept ultraviolet ray irradiation and vitamin D synthesis capability all not enough, muscle decay syndrome is also impotence card in the traditional Chinese medical science, the traditional Chinese medical science had more deep understanding to " impotence card " before 2000, no matter be in "Nei Jing", Systematic Compilation of Internal Classic, " Plain Questions. impotence opinion " or the famous medical book of Jing-Yue Complete Works etc. in, the Etiological that many name doctors prove " impotence card " is always to possess father and mother's deficiency of kidney-QI due to external damage or patient, cause patient's vital essence deficiency, liver-kidney deficiency, lose the day after tomorrow and support, deficiency-weakness of spleen-QI and causing a disease, Huangdi's Internal Classics is established " impotence card " specially section, the etiology and pathogenesis that impotence is demonstrate,proved is as the comparatively detailed description of system, the viewpoint that " scorched lung " is the main interpretation of the cause, onset and process of an illness has been proposed, because lung occupies high-order, for the canopy of the vital organs of the human body, therefore taking " scorched lung " as causing the main cause of impotence, the generation of the five internal organs pathology, the heat due to visceral-qi, or hindered by feelings will, or by old renal failure, or by damp and hot contamination, and the key of pathology, be muscles and bones, it is foster that muscle etc. lose moistening of qi-blood-body fluid, later age doctor on this basis, by practice, further recognize negative and positive, qi and blood, the void of body fluid, wet phlegm, hemostasis, the trouble of dyspepsia, all can make people become impotence, " integration of drinking and medicinal herbs " is one of contribution to mankind's most worthy among Chinese original medical science, the traditional Chinese medical science always emphasize " medication not as dietotherapy ", dietotherapy become modern pursue recover one's original simplicity, the optimal selection of health diet, allow people dispel slight illness in the process of enjoying cuisines, avoided having an injection, taking medicine, even the hardship of operation.

For food of special nutrients, there are corresponding regulation and Application and Development in the developed country such as the U.S., European Union; And wholefood clearly specifies in China GB29922-2013 " special medicine purposes formula food general rule " national food safety standard: the full nutrient formulation food of 2.1.1: the special medicine purposes formula food that can be used as single source of nutrition and meet target group's nutritional need; 2.1.2 specific full nutrient formulation food: the special medicine purposes formula food that can be used as single source of nutrition and meet target group's nutritional need under specified disease or medical condition.

Traditional Chinese medical science traditional medicine is thought: " spleen (being digestive system) is the foundation of acquired constitution ", stomach health is healthy basis, and 99% of human nutrition need to lean on intestinal absorption, and in intestines, disease is also the source of ten thousand diseases; But along with the age is larger, profitable strain in enteron aisle (probio) ratio reduces gradually; As Bifidobacterium Bifidum accounts for 98% period infant, during to the middle age, be down to and only account for 5% in 10%, 65 years old later; People is older, probio is fewer, function of intestinal canal also declines thereupon gradually, old muscle decay syndrome, main is exactly due to energy or protein insufficiency of intake, gastrointestinal dysfunction, and Disorder of Digestion and A orptions etc. cause, more and more studies show that, normal flora has many irreplaceable effects in human body digestion, immunity and the aspect such as disease-resistant; The generation development of change and the various diseases, particularly intestines problem of gut flora composition is closely related, and finds from existing clinical research: probio can play regulating intestinal canal flora, and control enteritis and levy effect, be that one is intervened control method safely and effectively.

Though directly probiotic oral has certain effect, but because probio one cannot field planting in enteron aisle, and stop, occupy-place are little, easily run off, and withdraw rear harmful bacteria and easily recur, and associated patient needs long-term taking, and treatment cycle is long, often uses rear recurrence rate very high, for shortening the treatment cycle of associated patient, recurrence rate after minimizing drug withdrawal, this team is by the key technology research to probio field planting mechanism in enteron aisle over nearly 3 year, make great efforts to seek to improve " medicine among integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, consider several key elements of probio field planting in enteron aisle: the existence of prebiotics can be played field planting effect, the enteron aisle adhesive capacity of the reduction of enteron aisle pH environment and raising probiotic cell etc., based on above-mentioned key element, suitable food materials screen from tens of kinds " medicines among integration of drinking and medicinal herbs " in this seminar, find first interpolation Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, the extract of the traditional Chinese medicine ingredients of the integration of drinking and medicinal herbs such as Gorgon fruit and jerusalem artichoke and stachyose, yeast, after Glu etc., external source probio is had to very strong field planting effect, for the prescription of probio in enteral microecological formulation selects to provide experimental basis.

Favourable is in the market primary raw material in order to eat source property small peptide, add the mushroom of medicine-food two-purpose, dried orange peel, matrimony vine, Chinese yam, Poria cocos, the extract of sealwort etc., B B-complex and mineral matter composition compound prescription, utilize in addition the product that probio is primary raw material, but also do not find the constitutive character in conjunction with muscle decay syndrome patient, according to the marrow theory of Traditional Chinese Medicine, vary with each individual, gold compatibility is with the Chinese medical extract elite of multiple medicine-food two-purpose, small peptide, multiple probio is primary raw material, with amino acid, prebiotics, carbohydrate, multivitamin, several mineral materials is the full nutrient formulation food that auxiliary material is made, specific full nutrient formulation food or similar products.

goal of the invention

The object of the invention is inheriting on the theoretical treatment method of traditional Chinese medical science marrow, the initiative probio by multiple raising muscle decay syndrome patient immunity combines with the extract of " medicine among integration of drinking and medicinal herbs " compound, add with small peptide, amino acid, carbohydrate, multivitamin, several mineral materials is auxiliary material, not only can supplement muscle decay syndrome patient institute essential nutrients, improve body nutrition condition, can also and utilize the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function, probio can play regulating intestinal canal flora, toxic and side effect is little, safe and effective, and the full nutrient formulation food that the acceptable applicable muscle decay syndrome patient of people eats, specific full nutrient formulation food or non-full nutrient formulation food.

summary of the invention:

This R&D team is according to the requirement of " special medicine purposes formula food general rule ", in conjunction with muscle decay syndrome patient's constitutive character, the comprehensively advanced physiology of nowadays American Harvard University, medicine, the achievement in research such as nutrition and clinical practice, according to " the middle residence that disappears is mended ", marrow theory (the liver of the Traditional Chinese Medicine of " equilibrium is taken good care of ", spleen, kidney three is dirty with being adjusted to main principle), adopt the Chinese medical extract elite of more than 4 kinds medicine-food two-purpose, small peptide, multiple probio is primary raw material, with amino acid, prebiotics, carbohydrate, multivitamin and mineral matter auxiliary material, not only can be used as the nutritional need that single source of nutrition meets muscle decay syndrome patient, also has tonifying middle-Jiao and Qi, yang invigorating, nourishing liver and kidney, the inducing resuscitation of having one's ideas straightened out, strong muscles and bones, dispelling wind and removing obstruction in the meridians, moisten the full nutrient formulation food of health flesh and enhancing body immunity, specific full nutrient formulation food or non-full nutrient formulation food (compound prescription being combined into).

1, the main component of the present invention's formula is:

Chinese medical extract is that the liver,spleen,kidney three from theory of traditional Chinese medical science is dirty with being adjusted to main principle according to muscle decay syndrome patient's constitutive character, utilize the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function to build up resistance, and choose following several large class medicine and carry out compatibility; During tonifying spleen is strong, replenishing qi and promoting blood flow, nourishing liver and kidney, strengthening the muscles and bones

Wherein: dendrobium candidum flavor efficacy: taste is sweet, cold nature, the nourishing the stomach of promoting the production of body fluid, nourishing Yin and clearing heat, moistening lung kidney-nourishing, the strong waist of improving eyesight, Cordyceps sinensis is warm in nature, and taste is sweet, has qi-restoratives and damages, benefit vital essence, relieving cough and reducing sputum, anticancer anti-ageing effect, also has antibacterial, relieving asthma, cardiac stimulant, the effects such as step-down, the fruit of Chinese magnoliavine is astringed the lung, and nourshing kidney is promoted the production of body fluid, and receives sweat, puckery essence, the seed of Chinese dodder " Mingyi Bielu " is called it to be had " supports flesh reinforcing yin essence, hard muscles and bones " effect, motherland's medical science is thought, seed of Chinese dodder acrid-sweet flavor, property is flat, enters liver, kidney two warps, have tonifying kidney and benefiting sperm, nourish the liver to improve visual acuity, antiabortive effect, enriches blood and invigorates blood circulation when attribution, swelling and pain relieving, effect of apocenosis myogenic, therefore can be used for traumatic injury, the cards such as ulcer sores, cultivated land taste is sweet, property flat and enter blood system, function nourishing yin and supplementing blood, mend lean marrow, the enriching yin of tortoise version, checking exuberance of yang, kidney tonifying, strong bone, Radix Astragali invigorating qi for strengthening superficies, diuresis holder poison, apocenosis, expelling pus and promoting granulation, the bighead atractylodes rhizome " medicine origin " is recorded: " dehumidifying benefit is dry, and middle beneficial gas, and Wen Zhong goes in taste wet, except stomach energy, and strong taste, enter diet, antiabortive, " plantain seed is sweet in flavor and cold in property, enters kidney, bladder, liver, lung channel, function promoting diuresis for stranguria, excreting dampness antidiarrheal, clear liver and improve vision, clearing heat and eliminating phlegm, Cordyceps militaris, the traditional Chinese medical science thinks, Chinese caterpillar fungus enters lung kidney two warps, can tonifying lung the moon, again can kidney-replenishing, cure mainly and suffer from a deficiency of the kidney, impotence and seminal emission, soreness of waist and knee joint, weak after being ill, chronic cough weakness, phthisical cough phlegm blood, spontaneous sweatings etc., are unique one balances simultaneously, regulate the Chinese medicine of negative and positive,

Medicinal and edible Chinese medicine extract of the present invention and new resource food refer to that dendrobium candidum, Cordyceps sinensis (aweto mycelium), lucidum spore powder (broken wall), glossy ganoderma, Cordyceps militaris, the fruit of Chinese magnoliavine, the seed of Chinese dodder, Radix Angelicae Sinensis, cultivated land, tortoise version, the Radix Astragali, the bighead atractylodes rhizome, plantain seed, the root of herbaceous peony, matrimony vine, raspberry, jujube kernel, honey-fried licorice root, fructus amomi, date, ginseng extract wherein 4 kinds are above or all, adopt biological enzymolysis or prehydrolysis SBE to extract and microencapsulation, the mixture after spray-dried and cryodesiccated extract.

2, multiple probio: make probio arrive enteron aisle by most of strong acid environment by stomach, to promote the propagation of probio, regulate microecological balance in intestines, promote micro-absorption, strengthen taste motor function, accelerate the absorption of drug effect, improve the micropopulation of mucous membrane surface or the balance of enzyme, or stimulate body specificity or nonspecific immunity mechanism, improve body field planting drag or immunity; Xing etc. are with Bifidobacterium and Bacillus acidi lactici pretreatment law during ischemia/reperfusion rat, can obviously reduce level that intestines source property endotoxin blood levies the generation of preventing liver injury; It is also the important measures of adjusting intestinal microecology that selective enteron aisle decontamination is dyed, and has research application enteron aisle not absorb rifamycin antibiotic former times bright (rifaximin), by suppressing urease-producing in enteron aisle and producing the growth of ammonium bacteria, builds up resistance;

Multiple probio of the present invention all adopts the probio after microencapsulation, except streptococcus thermophilus, wherein Bifidobacterium: refer to wherein a kind of, several or all mixing of bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum; Lactobacillus refers to: lactobacillus acidophilus powder, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus be a kind of, several or all mixing wherein.

3, small peptide: be oligopeptide, refer to the small molecule protein that utilizes bio-enzyme engineering technology separation and Extraction from animal or vegetable protein, its mean molecule quantity is below 1000Dalton, soluble in water, to acid, thermally-stabilised, can not need through digestion and directly absorb, bioavailability is high, in absorption and utilization, be better than free amino acid and complete protein, can be applicable in Protein intake food, especially for the low crowd of abilities of digestive and absorption, small peptide is splendid nitrogenous source, except trophic function, small peptide also has a series of physiological active functions: the digestion and absorption function that improves small intestine, strengthen immunity of organisms, anti-oxidant, auxiliary adjustment blood sugar, auxiliary adjustment of blood fat, aided blood pressure-lowering, radioresistance, promote mineral absorption, strengthen the action effect of function factor in medicine-food two-purpose Chinese herbal medicine,

Small peptide of the present invention refers to wherein a kind of, several or all mixing of marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide.

4, prebiotics: to urge the field planting of probio enteron aisle, enteron aisle convergence, to reduce enteron aisle pH environment, also do not utilized by most enteron aisle spoilage organisms, but can promote beneficial bacteria---the growth and breeding of lactobacillus, Bifidobacterium in human body, thereby can suppress spoilage organisms growth, contribute to improve and maintain enteron aisle normal function; Long-term edible can delay senility, defaecation, raising immunity, alleviate burden of liver, improve the absorptivity of nutrient, particularly can improve the absorption of body to metal ions such as calcium, iron, zinc; Optionally promote outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also can metabolism be acid product as organic acids such as lactic acid, pH value in colon is reduced, the growth of inhibition harmful intestinal tract bacterium; Make Water-Electrolyte in small intestine be trapped in enteric cavity, produce the high effect of oozing, stimulate enterocinesia to cause laxative, thereby promote the discharge of intestinal endotoxin and other toxicants, lactulose also directly endotoxin in deactivation enteron aisle, reduce enteron aisle pH value, extensively model is applied to the anti-muscle syndrome of decaying;

Prebiotics of the present invention is 2 classes

A. external source probio is had to very strong field planting effect prebiotics: the extract of Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke, stachyose, yeast several or all mixing wherein;

B. common prebiotics: oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one, several or all mixing wherein;

Originally refer to one, several or all mixing wherein of oligoisomaltose, stachyose, FOS, soyabean oligosaccharides, xylo-oligosaccharide.

5, carbohydrate: carbohydrate is by carbon, three kinds of element compositions of hydrogen and oxygen, it be for human body provide three kinds of heat energy main nutrient in the most cheap nutrient, while taking in abundance, can be oxidized rapidly energy is provided in time in vivo, avoid valuable protein to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the important composition composition of the glycolipid of nerve fiber and the DNA conveying hereditary information (DNA), and the glycogen containing in carbohydrate, in the time that it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin of some poisonous chemical substance and the generation of various pathogenic microorganisms,

Carbohydrate of the present invention refers to one, several or all mixing wherein of glucose, fructose, galactolipin, lactose, glucose, maltose, Arabinose, water-soluble dietary fiber, starch, glycogen.

6. amino acid: being divided into essential amino acid and nonessential amino acid, is the base unit that forms protein, gives protein specific molecular morphosis, makes it have biochemical activity; Absorbing appropriate methionine contributes to the metabolism of various sulfur-containing compounds in human body and its contained methyl to methylate to Toxic or medicine and the effect of playing removing toxic substances; Leucine can be repaired muscle, controls blood sugar, and provides energy to bodily tissue, essential amino acid phenylalanine can suppress the growth of cancer knurl, can reduce again the toxic and side effect of medicine, and lysine can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development; Arginine contributes to the ammonia in blood change urea into and excrete out; Levy for hyperammonemia, liver dysfunction etc. are all powerful; Histidine reduces gastric acidity, relaxes the pain of gastrointestinal procedures, alleviates gestational period vomiting and scorching hot sense, suppresses alimentary canal nervous by vegetative nerve and that cause and festers, to anaphylactia, as also powerful in asthma etc.; Tryptophan can prevent pellagra, depression to levy, and improves sleep and regulates mood;

Amino acid of the present invention refers to one, several or all mixing wherein of Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine.

7. vitamin and mineral matter:

Vitamin and mineral matter are the nutrients of needed by human, and the vitamin adding in the present invention is that vitamin and mineral matter are the nutrients of needed by human;

The vitamin adding in the present invention is one, several or all mixing wherein of vitamin A, vitamin D, vitamin E, vitamin K, phytomenadione, vitamin C, vitamin B1, vitamin B2, pyridoxamine, cobalamin, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin;

The mineral matter adding in the present invention is one, several or all mixing wherein of calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum, and mineral matter of the present invention is added to the organic or inorganic compound of this mineral matter;

In the present invention, the addition of vitamin and minerals is with reference to GB14880 " food enrichment use sanitary standard ", GB2760 " food additives use standard " carries out, now taking 1000g finished product as example, addition is vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.

8. the present invention is dried and freeze drying integrated innovation with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, efficiently solves high temperature and the deactivation of strong acid gastric juice to probio in oral process; Adopt three layers of buried microcapsules technology of protein, extract with through biological enzymolysis or prehydrolysis SBE technology again and microencapsulation Chinese medical extract after treatment mixes, to solve the coexistence problems of " multiple probio " and " medicine among integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and arrive in enteron aisle and stop field planting by gastric juice smoothly by oral, make the anti-muscle of product decay syndromic effect compared with the like product of market significantly improve.

9. adopt above-mentioned integrated innovation technique various batchings to be mixed to solid beverage, the granule of making powdery, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material to make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if making beverage saves spray-dried, add less auxiliary material etc., be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day was respectively drunk 1 bottle, and all operations all carries out in the clean dried environment that meets " the good production specification of special medicine purposes formula food " requirement.

This characteristic of full nutrient formulation food and the effect of body is mainly manifested in to the following aspects of filling a prescription:

1. the present invention is the requirement according to " special medicine purposes formula food general rule ", in conjunction with muscle decay syndrome patient's constitutive character, the achievement in research developments such as advanced physiology, medicine, nutrition and the clinical practice of comprehensive nowadays American Harvard University, vary with each individual, gold compatibility.

2. the present invention is according to the marrow theory (liver,spleen,kidney three is dirty with being adjusted to main principle) of the Traditional Chinese Medicine of " the middle residence that disappears is mended ", " equilibrium is taken good care of ", adopting the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is primary raw material, taking prebiotics, carbohydrate, amino acid, multivitamin and mineral matter as auxiliary material, the organic assembling of various batchings, various functions are merged, and by the synergy between active ingredient, humidification effect.

3. have efficient absorption, utilize formula of the present invention, various components adopt the food of suitable ratio collocation preparation, the state that oozes such as after a certain amount of water-soluble solution, be, can arrive small intestine by stomach fast, absorption fast, completely, can supplement rapidly muscle decay syndrome patient desired nutritional.

4. in the present invention's formula, adopt the extract of various medicine-food two-purpose Chinese herbal medicines, contain several functions active component, not only improve the concentration of function factor, reduce the absorption of various impurity, contribute to alleviate liver kidney burden, there is the effect that strengthens resistance of human body, also has tonifying middle-Jiao and Qi, yang invigorating, nourishing liver and kidney, the inducing resuscitation of having one's ideas straightened out, strong muscles and bones, dispelling wind and removing obstruction in the meridians, moisten health flesh and strengthen body immunity effect.

5. contained probio in the present invention's formula, multiple probio can be safeguarded enteron aisle normal bacteria colony balance, suppress the growth of pathogen, prevent gastrointestinal disorders etc., synthetic vitamin in enteron aisle, amino acid and the absorption of raising body to calcium ion, strengthen human immunologic function, prevent antibiotic side effect, improve the tolerance of host to radioactive ray, lactobacillus significantly increases intestinal mucosa immunoglobulin A (SIgA) content, body intestinal mucosa local immunity is had to regulating action, regulate stomach, the micro-ecology of intestines, can improve calcium, phosphorus, the utilization rate of iron, promote the absorption of iron and vitamin D, produce vitamin K and Cobastab, can also reduce the absorption of cholesterol.

6. formula food of the present invention is taking the food source inhibition biological active small peptide in multiple source as nitrogenous source, because small peptide does not need digestion to absorb, more be conducive to the utilization of body, can effectively improve muscle decay syndrome patient negative nitrogen balance, and food source property small peptide can improve the 26S Proteasome Structure and Function of intestinal epithelial cell, the absorbability of raising intestinal mucosa.

7. this prescription adopts Liao Ben team by the achievement of the key technology research to probio field planting mechanism in enteron aisle over nearly 3 year, improve " medicine among integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, the existence that combines prebiotics can be played the key element such as the reduction of field planting effect, enteron aisle pH environment and the enteron aisle adhesive capacity of raising probiotic cell, and therefore the composition of this food formula has strengthened the field planting effect to external source probio greatly.

8. contained prebiotics in the present invention's formula; by promoting the growth and breeding of probio in intestines; suppress the growth of spoilage organisms; form one protective barrier on intestinal mucosa surface simultaneously; can resist the damage of enteron aisle spoilage organisms to intestinal mucosa; reduce the absorption of intestinal toxic material; can also promote intestines peristalsis; accelerate the discharge of residuals in intestines; can prevent constipation; and also can strengthen immunity of organisms by the growth and breeding that promotes beneficial bacteria of intestinal tract, the bioactivators such as small peptide, carbohydrate and active polysaccharide have synergy.

9, in the present invention formula contained carbohydrate be for human body provide three kinds of heat energy main nutrient, can be oxidized rapidly energy is provided in time in vivo, avoid valuable protein to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the important composition composition of the glycolipid of nerve fiber and the DNA conveying hereditary information (DNA), and the glycogen containing in carbohydrate, in the time that it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin of some poisonous chemical substance and the generation of various pathogenic microorganisms.

10, contained amino acid in the present invention's formula, it is the base unit that forms protein, give protein specific molecular morphosis, make it have biochemical activity, contribute to the metabolism of various sulfur-containing compounds in human body and its contained methyl to methylate to Toxic or medicine and play the effect of removing toxic substances, can repair muscle, control blood sugar, and provide energy to bodily tissue, also can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development.

11, formula food of the present invention is containing multivitamin and mineral matter, can supplement rapidly the muscle required micronutrient of syndrome patient of decaying, small peptide by with the chelating of calcium, iron, zinc etc. after, more increased the absorptivity of mineral matter element.

12, not fatty and cholesterol in the present invention's formula, can, in supplementary protein, micronutrient, can not increase the absorption of fat, cholesterol, has avoided the adverse effect of the high protein diet such as meat, egg.

Detailed description of the invention

Below by following examples, the invention will be further described, and it will contribute to understand the present invention.

Embodiment mono-

Realizing the full nutrient formulation food of the object of the invention muscle decay syndrome is with the constitutive character in conjunction with muscle decay syndrome patient, according to the marrow theory of Traditional Chinese Medicine, vary with each individual, gold compatibility is taking the Chinese medical extract elite of more than 4 kinds medicine-food two-purpose, small peptide, multiple probio as primary raw material, taking amino acid, prebiotics, carbohydrate, multivitamin, several mineral materials as food auxiliary, that material is made;

Fill a prescription by following raw materials according and consumption thereof: the extract of medicine-food two-purpose: dendrobium candidum 14g, Cordyceps sinensis (aweto mycelium) 14gg, lucidum spore powder (broken wall) 14g, glossy ganoderma 12g, Cordyceps militaris 12g, fruit of Chinese magnoliavine 12g, seed of Chinese dodder 10g, Radix Angelicae Sinensis 10g, cultivated land 10g, tortoise version 10g, Radix Astragali 10g, bighead atractylodes rhizome 8g, plantain seed 8g, root of herbaceous peony 8g, matrimony vine 8g, raspberry 8g, jujube kernel 8g, honey-fried licorice root 6g, fructus amomi 6g, date 6g, ginseng 6g, small peptide 280g, Bifidobacterium 75g, lactobacillus 75g, streptococcus thermophilus 20g, several amino acids 150g, prebiotics 100g, carbohydrate 50g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,

First will be to be dendrobium candidum when making, Cordyceps sinensis (aweto mycelium), glossy ganoderma, Cordyceps militaris, the fruit of Chinese magnoliavine, the seed of Chinese dodder, Radix Angelicae Sinensis, cultivated land, tortoise version, the Radix Astragali, the bighead atractylodes rhizome, plantain seed, the root of herbaceous peony, matrimony vine, raspberry, jujube kernel, honey-fried licorice root, fructus amomi, date, ginseng, the membrane of a chicken's gizzard, Chinese yam, heart of a lotus seed benevolence, Gorgon fruit adds cycloheptaamylose after soaking, after extracting by prehydrolysis SBE technology, spray-dried and preparation flour, add again the small peptide that biological enzymolysis extracts, prebiotics, amino acid, lucidum spore powder (broken wall), carbohydrate, after being pulverized and mixed together, multivitamin and mineral matter carry out pasteurization 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage of making powdery, granule, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material to make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if making beverage saves spray-dried, add less auxiliary material etc., be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day was respectively drunk 1 bottle, and all operations all carries out in the clean dried environment that meets " the good production specification of special medicine purposes formula food " requirement.

Embodiment bis-

The full nutrient formulation food of above-mentioned muscle decay syndrome also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 24g, matrimony vine 24g, raspberry 22g, jujube kernel 22g, honey-fried licorice root 20g, fructus amomi 20g, date 20g, ginseng 18g, small peptide 280g, Bifidobacterium 75g, lactobacillus 75g, streptococcus thermophilus 20g, several amino acids 150g, prebiotics 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, phytomenadione 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, pyridoxamine 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.

Embodiment tri-

The full nutrient formulation food of above-mentioned muscle decay syndrome also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 24g, matrimony vine 24g, raspberry 22g, jujube kernel 22g, honey-fried licorice root 20g, fructus amomi 20g, date 20g, ginseng 18g, small peptide 280g, Bifidobacterium 75g, lactobacillus 75g, streptococcus thermophilus 20g, several amino acids 150g, prebiotics 100g, carbohydrate 100g.

The present invention is dried and freeze drying integrated innovation with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, efficiently solves high temperature and the deactivation of strong acid gastric juice to probio in oral process; Adopt three layers of buried microcapsules technology of protein, extract with through biological enzymolysis or prehydrolysis SBE technology again and microencapsulation Chinese medical extract after treatment mixes, to solve the coexistence problems of " multiple probio " and " medicine among integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and arrive in enteron aisle and stop field planting by gastric juice smoothly by oral, make the anti-muscle of product decay syndromic effect compared with the like product of market significantly improve.

Claims

1. the full nutrient formulation food of muscle decay syndrome, it is characterized in that with the constitutive character in conjunction with muscle decay syndrome patient, according to the marrow theory of Traditional Chinese Medicine, vary with each individual, gold compatibility is taking the Chinese medical extract elite of more than 4 kinds medicine-food two-purpose, multiple probio, small peptide as primary raw material, the food of making as auxiliary material taking prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials;

Its preparation method is for first will be to be dendrobium candidum, Cordyceps sinensis (aweto mycelium), glossy ganoderma, Cordyceps militaris, the fruit of Chinese magnoliavine, the seed of Chinese dodder, Radix Angelicae Sinensis, cultivated land, tortoise version, the Radix Astragali, the bighead atractylodes rhizome, plantain seed, the root of herbaceous peony, matrimony vine, raspberry, jujube kernel, honey-fried licorice root, fructus amomi, date, ginseng, the membrane of a chicken's gizzard, Chinese yam, heart of a lotus seed benevolence, Gorgon fruit adds cycloheptaamylose after soaking, after extracting by prehydrolysis SBE technology, spray-dried and preparation flour, add again the small peptide that biological enzymolysis extracts, prebiotics, amino acid, lucidum spore powder (broken wall), carbohydrate, multivitamin and mineral matter carry out pasteurization 1 hour after mixing, then add the Bifidobacterium after microencapsulation, lactobacillus, the various batchings that streptococcus thermophilus also adds appropriate carbohydrate mixing again mix the solid beverage of making powdery, granule, and be distributed into 10g/ bag, after dissolving by about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material to make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if making beverage saves spray-dried, add less auxiliary material etc., be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day was respectively drunk 1 bottle, and all operations all carries out in the clean dried environment that meets " the good production specification of special medicine purposes formula food " requirement.

2. the full nutrient formulation food formula of muscle decay syndrome according to claim 1, is characterized in that described medicine-food two-purpose Chinese herbal medicine extract is: 4 kinds of above or all mixing wherein of dendrobium candidum, Cordyceps sinensis (aweto mycelium), lucidum spore powder (broken wall), glossy ganoderma, Cordyceps militaris, the fruit of Chinese magnoliavine, the seed of Chinese dodder, Radix Angelicae Sinensis, cultivated land, tortoise version, the Radix Astragali, the bighead atractylodes rhizome, plantain seed, the root of herbaceous peony, matrimony vine, raspberry, jujube kernel, honey-fried licorice root, fructus amomi, date, ginseng.

3. the full nutrient formulation food formula of muscle decay syndrome according to claim 1, is characterised in that according to described formula and mixes and can be prepared into powdery, graininess, capsule shape, tablet shape, beverage based food.

4. the full nutrient formulation food formula of muscle according to claim 1 decay syndrome, is characterized in that described prebiotics is. to external source probio, to have very strong field planting effect prebiotics be wherein several of extract, stachyose, yeast and common prebiotics of Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke or all mix.

5. require the full nutrient formulation food formula of muscle decay syndrome described in 1, it is characterized in that described amino acid is one, several or all mixing wherein of Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine.

6. the full nutrient formulation food formula of muscle decay syndrome according to claim 1, is characterized in that described carbohydrate is one, several or all mixing wherein of glucose, fructose, galactolipin, lactose, glucose, maltose, Arabinose, water-soluble dietary fiber, starch, glycogen.

7. the full nutrient formulation food formula of muscle decay syndrome according to claim 1, is characterized in that being dried and freeze drying integrated innovation with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying the key technology that the industrialization of formation is produced; Microencapsulation resist technology, efficiently solves high temperature and the deactivation of strong acid gastric juice to probio in oral process; Adopt three layers of buried microcapsules technology of protein, extract with through biological enzymolysis or prehydrolysis SBE technology again and microencapsulation Chinese medical extract after treatment mixes, to solve the coexistence problems of " multiple probio " and " medicine among integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and arrive in enteron aisle and stop field planting by gastric juice smoothly by oral, product control muscle decay syndrome effect is significantly improved compared with the like product of market.

8. the full nutrient formulation food formula of muscle decay syndrome according to claim 1, is characterized in that described vitamin is one, several or all mixing wherein of vitamin A, vitamin D, vitamin E, vitamin K, phytomenadione, vitamin C, vitamin B1, vitamin B2, pyridoxamine, cobalamin, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin; Described mineral matter is one, several or all mixing wherein of calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum.

9. the full nutrient formulation food formula of muscle decay syndrome according to claim 1, is characterized in that described small peptide is wherein a kind of, several or all mixing of marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide.