CN104042701B - Guttural tablets - Google Patents
Guttural tablets Download PDFInfo
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- CN104042701B CN104042701B CN201410194959.3A CN201410194959A CN104042701B CN 104042701 B CN104042701 B CN 104042701B CN 201410194959 A CN201410194959 A CN 201410194959A CN 104042701 B CN104042701 B CN 104042701B
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- radix
- bgreatt
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- buccal tablet
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- 201000007100 Pharyngitis Diseases 0.000 claims abstract description 15
- 239000003814 drug Substances 0.000 claims abstract description 14
- 229940046011 buccal tablet Drugs 0.000 claims abstract description 11
- 239000006189 buccal tablet Substances 0.000 claims abstract description 11
- 239000008517 radix Trichosanthis Substances 0.000 claims abstract description 7
- 241000628997 Flos Species 0.000 claims abstract description 6
- 241000411851 herbal medicine Species 0.000 claims abstract description 6
- 241000903946 Clematidis Species 0.000 claims abstract description 5
- 239000008103 glucose Substances 0.000 claims abstract description 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 4
- 238000010298 pulverizing process Methods 0.000 claims abstract description 3
- 238000003756 stirring Methods 0.000 claims abstract description 3
- 230000000694 effects Effects 0.000 description 10
- 229940079593 drug Drugs 0.000 description 7
- 206010011224 Cough Diseases 0.000 description 6
- 239000008361 herbal raw material Substances 0.000 description 6
- 210000003800 pharynx Anatomy 0.000 description 6
- 230000003203 everyday effect Effects 0.000 description 5
- 206010068319 Oropharyngeal pain Diseases 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 239000003440 toxic substance Substances 0.000 description 3
- 241000251468 Actinopterygii Species 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 230000036760 body temperature Effects 0.000 description 2
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- 238000005516 engineering process Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000035611 feeding Effects 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 210000004877 mucosa Anatomy 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 238000007674 radiofrequency ablation Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 241000321096 Adenoides Species 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 241000186216 Corynebacterium Species 0.000 description 1
- 241000125183 Crithmum maritimum Species 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010013952 Dysphonia Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 208000010473 Hoarseness Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 241000193998 Streptococcus pneumoniae Species 0.000 description 1
- 241001122767 Theaceae Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 210000002534 adenoid Anatomy 0.000 description 1
- 238000003915 air pollution Methods 0.000 description 1
- GZCGUPFRVQAUEE-SLPGGIOYSA-N aldehydo-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O GZCGUPFRVQAUEE-SLPGGIOYSA-N 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
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- 206010013023 diphtheria Diseases 0.000 description 1
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- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
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- 238000009472 formulation Methods 0.000 description 1
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- 230000002949 hemolytic effect Effects 0.000 description 1
- 230000007365 immunoregulation Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 229940079322 interferon Drugs 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
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- 206010044008 tonsillitis Diseases 0.000 description 1
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- 230000001988 toxicity Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
A kind of Chinese herbal medicine buccal tablet for the treatment of pharyngitis, it is characterized in that its one-tenth be grouped into and proportioning as follows: Flos Trollii 20%, Radix Clematidis? 10%, Radix Adenophorae (Radix Glehniae) 8%, <b> Radix Trichosanthis </b><bGreatT.Gre aT.GT8%, </b><bGreatT.Gre aT.GT Herba Rostellulariae </b><bGreatT.Gre aT.GT3%, </b><bGreatT.Gre aT.GT Herba Menthae </b><bGreatT.Gre aT.GT1%, </b><bGreatT.Gre aT.GT glucose </b><bGreatT.Gre aT.GT50%, </b> is by said medicine, stir after pulverizing, make buccal tablet.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of pharyngitis.A kind of specifically take Chinese herbal medicine as the buccal tablet that raw material is prepared from.
Background technology
Pharyngitis is under pharyngeal mucosa, mucosa and adenoid diffuse inflammation, often with other upper respiratory disease, is a kind of disease of pharynx very common in crowd.Show as: pharyngeal discomfort, have foreign body sensation, irritative cough, drying, swell, block, pruritus etc., due to air pollution, with bad living habit, send out the trend that patient has growth in recent years.At present, the Therapeutic Method for pharyngitis has operative treatment, Microendoscopic radiofrequency ablation therapy and Drug therapy.Wherein operative treatment, Microendoscopic radiofrequency ablation therapy has good curative effect to early stage patient, but its treatment cost is expensive, is not easily accepted by patient.Although the medicine kind for the treatment of pharyngitis is in addition many, mostly expensive and poor effect.Some medicines.Dosage is large, but also can bring many side effect.Produce ill effect.
Summary of the invention
For overcoming the deficiencies in the prior art, the invention provides preparation prepared by a kind of Chinese herbal medicine for the treatment of pharyngitis, effectively can treat pharyngitis.And medication is few and facilitate, with low cost for solving the problems of the technologies described above, the present invention by following quality proportioning herbal raw material and
glucosemake: Flos Trollii 20% Radix Clematidis 10% Radix Adenophorae (Radix Glehniae) 8%
radix Trichosanthis 8% Herba Rostellulariae 3% Herba Menthae 1% glucose 50%
the present invention adoptsflos Trollii in herbal raw material is containing alkaloid, flavonoid, nature and flavor: bitter in the mouth, cold in nature, nontoxic, heat-clearing and toxic substances removing, control sense, tonsillitis, pharyngitis, Flos Trollii acid extraction, turn with chloroform the extract carrying gained again after alkalization, inhibitory action is had to gram-positive cocci and negative bacillus, to the antibacterial action of bacillus pyocyaneus, particularly evident, chmice acute experiment shows that its injection toxicity is very low, to liver, renal function and hemogram, all have no significant effect, the pathological examination of pluck, also without obviously changing, conventional Flos Trollii among the people is made tea to control and is had sore throat, Flos Trollii is monarch drug of the present invention.
the present invention adoptsradix Clematidis in herbal raw material belong to its root of medicinal plants and stem be used as medicine there is wind-damp dispelling, effect that the meridian dredging, the bone that disappears are choked.Radix Clematidis is ministerial drug of the present invention.
the present invention adoptsradix Glehniae in herbal raw material is the dry root of samphire Radix Glehniae.Property sweetness and bitterness is lightly seasoned, is slightly cold.Sweet light, cold in nature, nontoxic.Lung yin is supported in clearing away lung-heat to relieve cough heat clearing away, clearing away lung-heat, and expelling phlegm for arresting cough controls deficient fever, and the moon hinders cough caused by dryness, thirsty and dry pharynx, and Radix Glehniae is adjuvant drug of the present invention.
the present invention adoptsradix Trichosanthis in herbal raw material has obvious immunoregulation effect, immunocompetence can be strengthened, Radix Trichosanthis decoct has certain inhibitory action to Hemolytic streptococcus, Diplococcus pneumoniae, diphtheria corynebacterium in vitro, and this inhibitory action may be the another kind of protein with wide spectrum antitoxic action after interferon with Radix Trichosanthis, and Radix Trichosanthis is also adjuvant drug of the present invention.
the present invention adoptsin herbal raw material
herba Rostellulariaenature and flavor are salty flat, heat-clearing and toxic substances removing, treatment cough, and throat is had sore throat, and Herba Menthae acrid in the mouth is cool in nature; Return lung, Liver Channel; Delicate fragrance rises loose; There is wind-dispelling heat-dissipating, refresh oneself, the effect of throat, cure mainly pain dizzy, conjunctival congestion pharyngalgia celostomia.
herba Rostellulariae, Herba Menthaemedicine is made for of the present invention.By said herbal medicine by formula of the present invention and proportioning, stir after pulverizing, add equivalent glucose and correct the buccal tablet treatment pharyngitis that taste makes and have special effect, met Traditional Chinese Medicine heat-clearing and toxic substances removing, the dialectical Therapeutic Principle of YIN nourishing righting.We do the simple animal experiment of leachate also to above Six-element Chinese medicine, with the leachate feeding white mice two weeks of 5% concentration, every day 3 milliliters, divide three feedings, find the white mice zero difference with contrast blank assay group, do not find any toxic reaction, illustrate between Six-element Chinese herbal medicine, to there is not the restriction or checking relation in five elements phenomenon that should not combine such as contrary.
Detailed description of the invention
The present invention presses formulation ratio, makes buccal tablet according to a conventional method, every sheet 1 gram.Through clinical practice, general patient 3-5 days takes effect, and symptom is improved, and pain disappears, and throat is clearly comfortable, reaches therapeutic purposes, implements 80 many cases obvious effective rates more than 90%.
Case one: Zhang, female, 17 years old, private prosecution was had sore throat, and checked and found pharyngitis, and blood count leukocyte raises, 38 degree Celsius of body temperature.Take the buccal tablet that the present invention makes, every day buccal six times, about two hours are once, each 1-2 sheet, second day pain relief, 37.2 degree Celsius of body temperature.After three days, disappearance symptom, things are as usual, withdrawal.
Case two: field, man, 45 years old, private prosecution throat was felt bad, and fish spicule eaten by mistake by lunch, checked pharyngeal red, had no fish spicule and choke with sobs.Take the buccal tablet that the present invention makes, every day buccal six times, about two hours are once, each 1-2 sheet, after two days, disappearance symptom.
Case three: Hu, man, 40 years old, hoarseness, speech was painstaking.Take the buccal tablet that the present invention makes, every day buccal six times, about two hours are once, each 1, second day take a turn for the better, normal after five days.
Case four: land, female, private prosecution in 63 years old is had sore throat with the few expectorant of dry cough.Take the buccal tablet that the present invention makes, every day buccal six times, about two hours are once, each 1, second day take a turn for the better, normal after four days.
Claims (1)
1. treat a Chinese herbal medicine buccal tablet for pharyngitis, it is characterized in that its one-tenth be grouped into and proportioning as follows:
Flos Trollii 20% Radix Clematidis 10% Radix Adenophorae (Radix Glehniae) 8%
radix Trichosanthis 8% Herba Rostellulariae 3% Herba Menthae 1% glucose 50%by said medicine, stir after pulverizing, make buccal tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410194959.3A CN104042701B (en) | 2014-05-11 | 2014-05-11 | Guttural tablets |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410194959.3A CN104042701B (en) | 2014-05-11 | 2014-05-11 | Guttural tablets |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104042701A CN104042701A (en) | 2014-09-17 |
| CN104042701B true CN104042701B (en) | 2016-02-03 |
Family
ID=51496424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410194959.3A Expired - Fee Related CN104042701B (en) | 2014-05-11 | 2014-05-11 | Guttural tablets |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104042701B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927313A (en) * | 2005-09-07 | 2007-03-14 | 梁珍惠 | Pharmaceutical composition for treating pharyngitis |
| EP1977757A2 (en) * | 2006-03-01 | 2008-10-08 | Divapharma Chur AG | Use of Pelargonium in combination with Plantago for the preparation of a medicament for the prevention/treatment of oral inflammation or pharyngitis |
-
2014
- 2014-05-11 CN CN201410194959.3A patent/CN104042701B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927313A (en) * | 2005-09-07 | 2007-03-14 | 梁珍惠 | Pharmaceutical composition for treating pharyngitis |
| EP1977757A2 (en) * | 2006-03-01 | 2008-10-08 | Divapharma Chur AG | Use of Pelargonium in combination with Plantago for the preparation of a medicament for the prevention/treatment of oral inflammation or pharyngitis |
Non-Patent Citations (1)
| Title |
|---|
| 咽喉病的实践与认识（续一）;耿鉴庭;《江苏医药》;19771231(第1期);第24-26页，尤其是第25页左栏第3段，第25页左栏第7段 * |
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| Publication number | Publication date |
|---|---|
| CN104042701A (en) | 2014-09-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Huang Han Inventor after: Huang Dong Inventor after: Li Na Inventor before: Hu Baoshan Inventor before: Lu Peiqun |
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| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160104 Address after: 403, room 1, unit 15, No. 156, Tianqiao Road, Junan County, Shandong, Linyi 276699, China Applicant after: Huang Han Applicant after: Huang Dong Applicant after: Li Na Address before: 201200 Shanghai Pudong New Area Chuansha 54 Lane 4, 502 stone Pirro Applicant before: Shanghai Pudong Gaoxing Biotechnology Research Institute |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP02 | Change in the address of a patent holder |
Address after: No. 026, No. two, Zhi Zhou, Chengguan Town, Xincheng County, the Guangxi Zhuang Autonomous Region Co-patentee after: Huang Dong Patentee after: Huang Han Co-patentee after: Li Na Address before: 403, room 1, unit 15, No. 156, Tianqiao Road, Junan County, Shandong, Linyi 276699, China Co-patentee before: Huang Dong Patentee before: Huang Han Co-patentee before: Li Na |
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| CP02 | Change in the address of a patent holder | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160203 Termination date: 20190511 |